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Response to the New MCAT Premedical Curriculum Recommendations March 2012 Response to the new MCAT PREMEDICAL CURRICULUM RECOMMENDATIONS American Society for Biochemistry and Molecular Biology USB® ExoSAP-IT® reagent is the Original ExoSAP-IT gold standard for enzymatic PCR cleanup. reagent means Why take chances with imitations? 100% sample recovery of PCR products in one step 100% trusted results. Single-tube convenience Proprietary buffer formulation for superior performance Take a closer look at usb.affymetrix.com/exclusive © 2012 Affymetrix, Inc. All rights reserved. contents MARCH 2012 On the cover: Charles Brenner and Dagmar Ringe offer news premedical curriculum 3 President’s Message recommendations in Branching careers in biochemistry response to the forthcoming revision 5 News from the Hill of the MCAT. Obama’s FY13 budget: a mixed bag 6 Women’s History Month 6 Help us build an online teaching tool 7 New Kirschstein biography 8 Member Update 9 Annual awards We hope you’re planning to tweet 9 ASBMB-Merck award winner Follow @asbmb and toast with 10 DeLano award winner us at the annual 11 Avanti young investigator award winner meeting. 25 12 Response to the new MCAT at #EB2012 features 16 Q&A with Steven P. Briggs, MCP associate editor 18 Q&A with Jerry Hart, MCP and JBC associate editor 20 Q&A with Paul Fraser, JBC associate editor Science writer Rajendrani Mukhopadhyay clarifies departments the record on protein Find out how immunoblotting. 34 22 Journal News students from 22 JBC: Viewing all reactive the University of species in one take Delaware keep 22 MCP: The role of antibody snagging poster glycosylation in vaccine effectiveness awards. 28 23 JLR: Legacy of a lipid pioneer 23 JBC: From butterflies to politicians 25 SciComm Speak, tweet and drink up! 26 Minority Affairs A life of, and for, change: profile of Dave R. Wilson 28 Education Shine at the undergrad poster competition 30 Lipid News Functions of cardiolipin as modifiers of the Barth syndrome phenotype onlineexclusives 32 Career Insights We’re pleased to announce that science writer Taking technology out of the lab and into the world Rajendrani Mukhopadhyay now has a blog. Follow her quips and queries at 34 Open Channels www.asbmb.org/asbmbtoday. 34 The men behind Western blotting 36 What people are reading March 2012 ASBMB Today 1 onlineexclusives A monthly publication of www.asbmb.org/asbmbtoday The American Society for Biochemistry and Molecular Biology Officers Suzanne R. Pfeffer President Jeremy M. Berg President-Elect Mark A. Lemmon Secretary Merle S. Olson Treasurer Treasurer-Elect Why so blue? Toni M. Antalis Council Members If biochemistry and molecular biology were Karen N. Allen Ruma V. Banerjee Benjamin F. Cravatt Michael A. Marletta a color, what would it be? Yes, it might seem David Sabatini John D. Scott Melissa Starovasnik Wesley I. Sundquist like a silly question. But we value your input Jonathan S. Weissman Ex-Officio Members as we begin strategizing about the future look Russell DeBose-Boyd Hongtao Yu of ASBMB Today. We hope you’ll take our Co-chairs, 2012 Annual Meeting Program Committee Peter J. Kennelly poll at http://bit.ly/zaDr77. So far, a majority Chair, Education and Professional Development Committee Joan W. Conaway of readers say blue is best, but there’s still Chair, Meetings Committee Terri Kinzy time to vote. Chair, Membership Committee Squire J. Booker Chair, Minority Affairs Committee Bettie Sue Masters Chair, Public Affairs Advisory Committee Charles Brenner REVIEW: RULE OF 6IX Chair, Publications Committee Martha J. Fedor, Editor-in-chief, JBC Herbert Tabor, Co-editor, JBC Ralph A. Bradshaw A. L. Burlingame Co-editors, MCP Edward A. Dennis Joseph L. Witztum Co-editors, JLR ASBMB Today Editorial Advisory Board Alex Toker (Chair) Mike Bradley Craig E. Cameron A. Stephen Dahms Alex C. Drohat Ben Ellington Irwin Fridovich Richard W. Hanson Gerald Hart Peter Kennelly Carol C. Shoulders ASBMB Today ASBMB Today contributor Aditi Das looks into Connor Bamford’s blog, “Rule Angela Hopp Editor [email protected] of 6ix.” Bamford, a Ph.D. student at Queen’s University in Belfast, takes on all Rajendrani Mukhopadhyay things virology and has a particular interest in the pathogenesis of mumps, Sr. Science Writer / Editor [email protected] which he’s working on at the Centre for Infection and Immunity. Erin Salb Production Coordinator [email protected] Nancy J. Rodnan Director of Publications [email protected] Barbara Gordon Executive Director [email protected] Need clips? For information on advertising, contact ASBMB Today is always seeking self-starting, Capitol Media Solutions at 800-517-0610 volunteer writers to craft news and feature articles or [email protected] for the website. We’re looking for storytellers who can identify trends, fairly analyze issues and identify best-suited sources for the stories at hand. For more www.asbmb.org/asbmbtoday information or to send a submission query, contact Editor Angela Hopp at [email protected]. March 2012 president’smessage Branching careers in biochemistry BY SUZANNE PFEFFER n Jan. 21, the American Society for OBiochemistry and Molecular Biology sponsored a wonderful event: 225 graduate students and postdoctoral fellows gathered in Genentech Hall at the University of California at San Francisco to devote a full day to the discussion of career options. The audience included representatives from Stanford University, UCSF, the University of California at Berkeley, San Jose State Univer- sity, San Francisco State University and Califor- nia State University at Fresno. The event was organized by four graduate students— Whitney Johnson and Siggy Nachtergaele of Stanford and David Pincus and Justin Rettenmeier of UCSF— with guidance from two faculty members, ASBMB Council member Jonathan Weissman of UCSF and me. Graduate students, from left, Whitney Johnson, Siggy Nachtergaele, Justin The program consisted of panel discussions Rettenmeier and David Pincus organized the ASBMB career symposium in on working in biotech; teaching in schools, col- late January at the University of California at San Francisco. leges and museums; starting companies; and practicing patent law. The lunch hour included breakout groups so that students could meet with repre- her colleagues found that the vast majority of students sentatives of the career paths in a more informal setting. (92.3 percent) were strongly considering careers in Reviews of the event were extremely positive, and several scientific research, and 72 percent of those students attendees inquired about organizing similar events at their were strongly considering a traditional academic career own institutions. path. On the other hand, when students were asked to The recipe for organizing this successful career day pick a single career option, only 44.8 percent chose a was really very simple. The organizers identified panel- traditional academic career path (1). Seventy-one percent ists by emailing faculty members and asking for sug- of all students surveyed were strongly considering at least gestions and contact information for recent graduates; one career path not directly involving scientific research. invited panelists suggested additional participants. By The most popular alternatives were business of science, inviting alumni of each of the schools, the program teaching or education, science policy, and writing. offered a layer of connectivity for all involved. Panelists Fuhrmann and colleagues also found that as students were pleased to participate and had fun in the process. got closer to completing of their degrees, they showed a decreased interest in becoming principal investigators A look at the motivating data at research-intensive institutions. The gender difference The program kicked off with a presentation by Cynthia also was striking: 21 percent of women and 39.5 per- Fuhrmann, the program director of academic career cent of men wanted to pursue this track. Students were development at UCSF. Fuhrmann summarized trends in concerned about inadequate quality of life or work-life career choices by recent graduates in biochemistry and balance, competition, stress, and challenges of research molecular biology. funding. Twenty-five percent wrote that they disliked After polling Ph.D. students at UCSF, Fuhrmann and tasks associated with being a PI, such as grant writing March 2012 ASBMB Today 3 president’sfirstsecondmessagecontinuedcontinued and project management. By the steer them toward middle-school later years of graduate school, and high-school teaching. My fully one-third of students stated bias is that they will have a much they would choose nonresearch broader impact as teachers of career paths (1). younger students; they will have With so many of our trainees the potential to interest someone choosing non-PI career paths, we in science for the first time and to need to embrace the branching educate the citizenry about the career pipeline. This is precisely scientific method and evidence- why the ASBMB has begun to LEFT: Cynthia Fuhrmann is the program director based conclusions. Given the support multiple career work- of academic career development within the number of our students who are Office of Career and Professional Development shops across the U.S. each and an assistant professor in biochemistry and interested in teaching, we should year. In addition to future faculty biophysics at the University of California at San all reach out to our schools of seminars, universities need to Francisco. education and design paths for initiate programs that teach skills RIGHT: Jonathan Weissman is a member of the students to earn joint Ph.D.s and that will benefit trainees preparing ASBMB Council and a professor of cellular and K–12 teaching experience and molecular pharmacology and of biochemistry for diverse career paths— skills in and biophysics at the University of California at credentials. oral and written communication, San Francisco. For trainees interested in teamwork, networking, project careers in biotech, more seem to management and leadership. We also need to reward be skipping the option of first completing a postdoctoral mentors for training students and fellows who move into fellowship in an academic lab.
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