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Rabbit Anti-ALF/FITC Conjugated antibody

SL5139R-FITC

Product Name: Anti-ALF/FITC Chinese Name: FITC标记的通用转录因子IIA样因子抗体 General transcription factor II A 1 like factor; GTF2A1LF; SALF; Stonin 1; TFIIA Alias: alpha and beta like factor; TF2AY_HUMAN; 1-like factor; General transcription factor II A; Gtf2a1l; TFIIA-alpha and beta-like factor. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat,Dog,Cow,Rabbit, IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 44kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human ALF Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01Mwww.sunlongbiotech.com TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involves the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. ALF is a germ cell-specific Product Detail: counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Function: May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.

Subcellular Location: Nucleus.

Tissue Specificity: Testis specific.

Similarity: Belongs to the TFIIA subunit 1 family.

Database links:

Entrez Gene: 11036 Human

Entrez Gene: 316711 Rat

Omim: 605358 Human

SwissProt: Q9UNN4 Human

Unigene: 44385 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

通用转录因子IIA样因子抗体又称TFIIAα/β样因子抗体。 www.sunlongbiotech.com