Role of TRPV1 in Colonic Mucin Production and Gut Microbiota Profile
bioRxiv preprint doi: https://doi.org/10.1101/2020.04.17.046011; this version posted April 18, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. 1 Role of TRPV1 in colonic mucin production and gut microbiota profile 2 Vijay Kumar1,2, Neha Mahajan1,3, Pragyanshu Khare1, Kanthi Kiran Kondepudi1, Mahendra 3 Bishnoi 1# 4 1National Agri-Food Biotechnology Institute (NABI), Knowledge City-Sector 81, SAS 5 Nagar, Punjab 140306, India. 6 2Department of Biotechnology, Panjab University, Sector-25, Chandigarh 160014, India. 7 3Regional Centre for Biotechnology, Faridabad-Gurgaon expressway, Faridabad, Haryana 8 121001, India. 9 Running title: TRPV1 and mucin production 10 #Corresponding author 11 Mahendra Bishnoi, PhD 12 Scientist and Group Leader, TR(I)P for Health Laboratory 13 Department of Food and Nutritional Biotechnology 14 National Agri-Food Biotechnology Institute (NABI), 15 Knowledge City-Sector 81, SAS Nagar, Punjab 140306, India. 16 Email: mbishnoi@nabi.res.in; mbishnoi@gmail.com 17 Phone no. +91-172-5220261; +91-9914469090 1 bioRxiv preprint doi: https://doi.org/10.1101/2020.04.17.046011; this version posted April 18, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. 18 ABSTRACT 19 PURPOSE: This study focuses on exploring the role of sensory cation channel Transient 20 Receptor Potential channel subfamily Vanilloid 1 (TRPV1) in gut health, specifically mucus 21 secretion and microflora profile in gut.
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