Redalyc.Pain Threshold Assessment in Relation to Neural Mobilization Therapy
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The Open Pain Journal, 2017, 10, 44-55 the Open Pain Journal
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Leeds Beckett Repository Send Orders for Reprints to [email protected] 44 The Open Pain Journal, 2017, 10, 44-55 The Open Pain Journal Content list available at: www.benthamopen.com/TOPAINJ/ DOI: 10.2174/1876386301710010044 REVIEW ARTICLE Effect of Age, Sex and Gender on Pain Sensitivity: A Narrative Review Hanan G. Eltumi1,2 and Osama A. Tashani1,2,* 1Centre for Pain Research, School of Clinical and Applied Sciences Leeds Beckett University, Leeds, UK. 2Department of Physiology, Faculty of medicine, University of Benghazi, Libya. Received: February 05, 2017 Revised: May 23, 2017 Accepted: May 26, 2017 Abstract: Introduction: An increasing body of literature on sex and gender differences in pain sensitivity has been accumulated in recent years. There is also evidence from epidemiological research that painful conditions are more prevalent in older people. The aim of this narrative review is to critically appraise the relevant literature investigating the presence of age and sex differences in clinical and experimental pain conditions. Methods: A scoping search of the literature identifying relevant peer reviewed articles was conducted on May 2016. Information and evidence from the key articles were narratively described and data was quantitatively synthesised to identify gaps of knowledge in the research literature concerning age and sex differences in pain responses. Results: This critical appraisal of the literature suggests that the results of the experimental and clinical studies regarding age and sex differences in pain contain some contradictions as far as age differences in pain are concerned. -
Estrogenic Influences in Pain Processing
Estrogenic influences in pain processing Asa Amandusson and Anders Blomqvist Linköping University Post Print N.B.: When citing this work, cite the original article. Original Publication: Asa Amandusson and Anders Blomqvist, Estrogenic influences in pain processing, 2013, Frontiers in neuroendocrinology (Print), (34), 4, 329-349. http://dx.doi.org/10.1016/j.yfrne.2013.06.001 Copyright: Elsevier http://www.elsevier.com/ Postprint available at: Linköping University Electronic Press http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-100488 Estrogenic Influences in Pain Processing Åsa Amandussona and Anders Blomqvistb aDepartment of Clinical Neurophysiology, Uppsala University, 751 85 Uppsala, Sweden, and bDepartment of Clinical and Experimental Medicine, Division of Cell Biology, Faculty of Health Sciences, Linköping University, 581 85 Linköping, Sweden. Correspondence to: Dr. Åsa Amandusson, E-mail: [email protected], or Dr. Anders Blomqvist, E-mail: [email protected] Amandusson & Blomqvist, page #2 Abstract Gonadal hormones not only play a pivotal role in reproductive behavior and sexual differentiation, they also contribute to thermoregulation, feeding, memory, neuronal survival, and the perception of somatosensory stimuli. Numerous studies on both animals and human subjects have also demonstrated the potential effects of gonadal hormones, such as estrogens, on pain transmission. These effects most likely involve multiple neuroanatomical circuits as well as diverse neurochemical systems and they therefore need to be evaluated specifically to determine the localization and intrinsic characteristics of the neurons engaged. The aim of this review is to summarize the morphological as well as biochemical evidence in support for gonadal hormone modulation of nociceptive processing, with particular focus on estrogens and spinal cord mechanisms. -
Pain Management & C.A.R.E.®
Creating Environments that Heal Pain Management & C.A.R.E.® By Susan E. Mazer, Ph.D President & CEO Healing HealthCare Systems, Inc. ABSTRACT Pain management has reached the apex of conflict between what patients have a right to expect and how physicians balance safe pain relief with suffering. With the Opioid Epidemic being attributed in part to the over-prescribing by physicians, the push to find alternatives is greater now than in the past. However, there is little understanding about the experience and mechanisms of pain and its management. This paper provides an overview of the history of pain theories and their relationship to patients’ empowerment in managing their conditions. The dictum that pain is not a disease, but rather a symptom, allows for broader understanding and exploration on a per patient basis. Theories that inform pain management practices, such as Focused Attention, Attention Restoration, and Restorative Environments are also reviewed. In addition, research that points to the patient’s pain beliefs, attitudes, and emotional state informing their capacity to self-regulate pain and the effectiveness of pain management strategies is discussed. The C.A.R.E. Channel and C.A.R.E. with Guided Imagery are discussed in the context of current pain management practices and creating an environment of care that is, itself, a means of mitigating pain. This includes concerns about comfort and self-management of pain that extend beyond hospitalization. CREATING ENVIRONMENTS THAT HEAL | WWW.HEALINGHEALTH.COM Page 1 Pain Management & C.A.R.E. By Susan E. Mazer, Ph.D President & CEO Healing HealthCare Systems, Inc. -
PDF (Thesis Document)
The experience of pain in the context of childbirth for Hong Kong Chinese women: a longitudinal cohort interview study Lee Lai Yin, Irene A thesis submitted in partial fulfillment for the requirements for the degree of Doctor of Philosophy at the University of Central Lancashire. July 2017 1 Student Declaration I declare that while registered as a candidate for the research degree, I have not been a registered candidate or enrolled student for another award of the University or other academic or professional institution. I declare that no material contained in the thesis has been used in any other submission for an academic award and is solely my own work. Signature of Candidate: Type of Award: Doctor of Philosophy School of Community Health and Midwifery 2 Abstract Childbirth, the biggest life event for a woman, is a complicated process. Childbirth pain not only involves physiological sensations, but also psychosocial and cultural factors. In addition, the way the woman handles the pain is affected by the meaning she attributes to it. In order to understand the experience of Hong Kong Chinese women in terms of childbirth in general and childbirth pain in particular, and to learn the meanings attributed, a longitudinal qualitative descriptive study was conducted with the aim of exploring the experience and meaning of pain in the context of childbirth for Hong Kong Chinese women. The study was informed by a systematic review and metasynthesis of existing relevant literature. Since people’s attitudes, beliefs and behaviours may change over a period of time, data were collected from the participants at 4 different time points: around 36 weeks of pregnancy; on postnatal day 3; 6-7 weeks after birth; and 10-12 months after birth. -
Inhibition of Autotaxin Activity Ameliorates Neuropathic Pain
www.nature.com/scientificreports OPEN Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis Baasanjav Uranbileg1, Nobuko Ito2*, Makoto Kurano1, Kuniyuki Kano3, Kanji Uchida2, Masahiko Sumitani4, Junken Aoki3 & Yutaka Yatomi1 Lumbar spinal canal stenosis (LSS) or mechanical compression of dorsal root ganglion (DRG) is one of the causes of low back pain and neuropathic pain (NP). Lysophosphatidic acid (LPA) is a potent bioactive lipid mediator that is produced mainly from lysophosphatidylcholine (LPC) via autotaxin (ATX) and is known to induce NP via LPA1 receptor signaling in mice. Recently, we demonstrated that LPC and LPA were higher in cerebrospinal fuid (CSF) of patients with LSS. Based on the possible potential efcacy of the ATX inhibitor for NP treatment, we used an NP model with compression of DRG (CD model) and investigated LPA dynamics and whether ATX inhibition could ameliorate NP symptoms, using an orally available ATX inhibitor (ONO-8430506) at a dose of 30 mg/kg. In CD model, we observed increased LPC and LPA levels in CSF, and decreased threshold of the pain which were ameliorated by oral administration of the ATX inhibitor with decreased microglia and astrocyte populations at the site of the spinal dorsal horn projecting from injured DRG. These results suggested possible efcacy of ATX inhibitor for the treatment of NP caused by spinal nerve root compression and involvement of the ATX-LPA axis in the mechanism of NP induction. Neuropathic pain (NP) is characterized by abnormal pain symptoms such as hyperalgesia and allodynia and is caused by damage to the peripheral or central nervous system 1,2. -
Therapeutic Guidelines in Chronic Low Back Pain
Pharmacia 68(1): 117–120 DOI 10.3897/pharmacia.68.e50297 Review Article Therapeutic guidelines in chronic low back pain Daniela Taneva1, Angelina Kirkova2, Pеtar Atanasov3 1 Medical University – Plovdiv, Department of Nursing, Faculty of Public Health, 15A Vasil Aprilov Blvd., Plovdiv 4002, Bulgaria 2 Medical University – Plovdiv, Department of Medical Informatics, Biostatistics and E-learning, Faculty of Public Health, 15A Vasil Aprilov Blvd., Plovdiv 4002, Bulgaria 3 Clinic of Internal Diseases, UMHATEM “N. I. Pirogov”, Sofia, Bulgaria Corresponding author: Angelina Kirkova ([email protected]) Received 20 January 2020 ♦ Accepted 27 January 2020 ♦ Published 8 January 2021 Citation: Taneva D, Kirkova A, Atanasov P (2021) Therapeutic guidelines in chronic low back pain. Pharmacia 68(1): 117–120. https://doi.org/10.3897/pharmacia.68.e50297 Abstract Chronic low back pain is a heterogeneous group of disorders with recurrent low back pain over 3 months. The high incidence of lumbago is an important phenomenon in our industrial society. Patients with chronic low back pain often receive multidisciplinary treatment. The bio approach, the psycho-approach, and the social approach optimally reduce the risk of chronicity by providing rehabilitation for patients with persistent pain after the initial acute phase. Damage to the structures of the spinal cord and the occur- rence of low back pain as a result of evolutionary, social and medical causes disrupt the rhythm of life and cause less or greater dis- ability. Recovery of patients with low back pain is not limited only to influencing the pain syndrome but requires the implementation of programs to eliminate the complaints that this pathology generates in personal, family and socio-professional terms. -
The Relation Between Tender Points and Fibromyalgia Symptom Variables
268 Annals of the Rheumatic Diseases 1997;56:268–271 CONCISE REPORTS Ann Rheum Dis: first published as 10.1136/ard.56.4.268 on 1 April 1997. Downloaded from The relation between tender points and fibromyalgia symptom variables: evidence that fibromyalgia is not a discrete disorder in the clinic Frederick Wolfe Abstract Fibromyalgia represents the intersection of a Objective—To investigate the relation considerably abnormal and reduced pain between measures of pain threshold and threshold with a series of clinical distress vari- symptoms of distress to determine if ables, including pain, fatigue, sleep distur- fibromyalgia is a discrete construct/ bance, anxiety, and depression, among others. disorder in the clinic. In the clinic, it is best diagnosed by counting Methods—627 patients seen at an the number of tender points a patient has. In outpatient rheumatology centre from 1993 the presence of 11 or more tender points and to 1996 underwent tender point and dolor- widespread pain, fibromyalgia is diagnosed (classified) according to American College of imetry examinations. All completed the Rheumatology (ACR) Criteria.1 assessment scales for fatigue, sleep The ability to diagnose fibromyalgia with disturbance, anxiety, depression, global commonly agreed upon criteria has stimulated severity, pain, functional disability, and a research into basic and clinic aspects of the composite measure of distress con- syndrome. In general, research has used structed from scores of sleep disturbance, ‘normals’ or patients with other rheumatic dis- fatigue, anxiety, depression, and global eases as control subjects. This comparison, of severity—the rheumatology distress index fibromyalgia with such control subjects, (RDI). implies that fibromyalgia is a discrete entity. -
Florence Hannah Renée Orlik PERSISTENT DENTO ALVEOLAR
Florence Hannah Renée Orlik PERSISTENT DENTO ALVEOLAR PAIN DISORDER : DIAGNOSTIC AND TREATMENT Universidade Fernando Pessoa – Faculdade de Ciências da Saúde Porto - 2017 Florence Hannah Renée Orlik PERSISTENT DENTO ALVEOLAR PAIN DISORDER : DIAGNOSTIC AND TREATMENT Universidade Fernando Pessoa – Faculdade de Ciências da Saúde Porto - 2017 Florence Hannah Renée Orlik PERSISTENT DENTO ALVEOLAR PAIN DISORDER : DIAGNOSTIC AND TREATMENT Monography presented to the University of Fernando Pessoa as part of the requirements for obtaining a Master's Degree in Dental Medicine PERSISTENT DENTO ALVEOLAR PAIN DISORDER : DIAGNOSTIC AND TREATMENT ACKNOWLEDGMENTS : « Travaillez, prenez de la peine : C’est le fonds qui manque le moins. Que le travail est un trésor! » Jean de La Fontaine, Le laboureur et ses enfants Thanks to my grannies for always being models of bravery for me. Thanks to my brother, the light of my life, which illuminates me immutably ; divine spark presents thanks to my exceptional parents. To my dear family, thank you for teaching me the love of hard work, to be always present and enthusiastic for all my projects and to love me as I am. Thanks to my best friend, my crime partner, for these good and studious moments spent together. Give thanks to our Lord, without Him no one is. « I will give thanks to you, Lord, with all my heart; I will tell of all your wonderful deeds. I will be glad and rejoice in you; I will sing the praises of your name, O Most High. » « The Lord reigns forever; he has established his throne for judgment. He rules the world in righteousness and judges the peoples with equity. -
Pain” in the Modern Neurosciences: a Historical Account of the Visualization Technologies Used in the Development of an “Algesiogenic Pathology”, 1850 to 2000
Brain Sci. 2015, 5, 521-545; doi:10.3390/brainsci5040521 OPEN ACCESS brain sciences ISSN 2076-3425 www.mdpi.com/journal/brainsci/ Review Objectifying “Pain” in the Modern Neurosciences: A Historical Account of the Visualization Technologies Used in the Development of an “Algesiogenic Pathology”, 1850 to 2000 Frank W. Stahnisch Department of Community Health Sciences & Department of History, The University of Calgary, 3280 Hospital Drive NW, Calgary T2N 4Z6, AB, Canada; E-Mail: [email protected]; Tel.: +1-403-210-6290. Academic Editor: Patrick W. Stroman Received: 31 August 2015 / Accepted: 9 November 2015 / Published: 17 November 2015 Abstract: Particularly with the fundamental works of the Leipzig school of experimental psychophysiology (between the 1850s and 1880s), the modern neurosciences witnessed an increasing interest in attempts to objectify “pain” as a bodily signal and physiological value. This development has led to refined psychological test repertoires and new clinical measurement techniques, which became progressively paired with imaging approaches and sophisticated theories about neuropathological pain etiology. With the advent of electroencephalography since the middle of the 20th century, and through the use of brain stimulation technologies and modern neuroimaging, the chosen scientific route towards an ever more refined “objectification” of pain phenomena took firm root in Western medicine. This article provides a broad overview of landmark events and key imaging technologies, which represent the long developmental path of a field that could be called “algesiogenic pathology.” Keywords: pain; history of medicine; Leipzig; Montreal; New York; nineteenth century; precursors to functional neuroimaging of pain; twentieth century “The past of a present-day science is not the same thing as that science in the past.” (Georges Canguilhem) [1] 1. -
Comparison of Pain Threshold and Duration of Pain Perception in Men
ISSN 0103-5150 Fisioter. Mov., Curitiba, v. 27, n. 1, p. 77-84, jan./mar. 2014 Licenciado sob uma Licença Creative Commons DOI: http://dx.doi.org.10.1590/0103-5150.027.001.AO08 [T] Comparison of pain threshold and duration of pain perception in men and women of different ages [I] Comparação do limiar de dor e tempo de percepção de dor em homens e mulheres de diferentes faixas etárias [A] Marília Soares Leonel de Nazaré[a], José Adolfo Menezes Garcia Silva[b], Marcelo Tavella Navega[c], Flávia Roberta Fagnello-Navega[d] [a] Physical therapist, graduated from the Faculty of Philosophy and Science, Unesp, Marília, SP - Brazil, e-mail: [email protected] [b] MSc in Human Development and Technology at the Faculty of Philosophy and Sciences, Unesp, Rio Claro, SP - Brazil, e-mail: [email protected] [c] PhD, professor of Physical therapist, Department of Special Education, Faculty of Philosophy and Science, Unesp, Marília, SP - Brazil, e-mail: [email protected] [d] PhD, professor of Physical therapy, Department of Special Education, Faculty of Philosophy and Science, Unesp, Marília, SP - Brazil, e-mail: [email protected] [R] Abstract Introduction: Pain is a sensory and emotional experience that occurs with the presence of tissue injury, actual or potential. Pain is subjective, and its expression is primarily determined by the perceived intensity of the painful sensation, called the pain threshold. Objective: To evaluate whether there are differences in pain threshold (LD) and time to pain perception (TPED) between the gender in different age groups and to analyze the correlation between age and pain threshold in each gender. -
Concentric Electrodes for Producing Acupuncture-Like Anesthetic Effects
Tohoku J. Exp. Med., 1990, 160, 169-175 Concentric Electrodes for Producing Acupuncture-Like Anesthetic Effects HIROHISAODA and YOSHIKOFUJITANI Department of Physiology, Tottori University School of Medicine, Yonago 683 ODA,H. and FUJITANI,Y. Concentric Electrodesfor Produci. Acupuncture- Like Anesthetic Effects. Tohoku J. Exp. Med., 1990, 160 (3), 169-175 We designed concentric electrodes composed of a center electrode and an outer ring electrode. Electrical stimulation with two sets of such electrodes for 15 min as conditioning stimuli was given to the left hand of 35 adult subjects to induce acupuncture-like anesthetic effects. The effects immediately after the condition- ing were compared between stimulation through a pair of center electrodes alone at 3 Hz (conditioning 1) and simultaneous stimulation of 3 Hz through a pair of center electrodes and 100 Hz through a pair of outer ring electrodes (conditioning 2). In conditioning 2, modulating effects of 100 Hz stimuli through a pair of outer ring electrodes made it possible to increase the voltage strength of 3 Hz stimuli through a pair of center electrodes with maintaining the minimum perception of pricking sensation. In both conditioning procedures, muscle twitching was not accompanied. It was found that the respective stimulating current thresholds for faint touch sensation and also for pricking sensation at the right forearm could be elevated significantly more by conditioning 2 (1.54 and 1.40 times) than by conditioning 1 (1.20 and 1.14 times). - acupuncture ; electroanalgesia ; electrodes ; sensory thresholds Low frequency electrical cutaneous stimulation evoking muscle twitch ele- vates the threshold of pain sensation like acupuncture anesthesia (Andersson and Holmgren 1975; Hans and Terenius 1982). -
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ORIGINAL CONTRIBUTION Osteopathic manipulative treatment in conjunction with medication relieves pain associated with fibromyalgia syndrome: Results of a randomized clinical pilot project RUSSELL G. GAMBER, DO; JAY H. SHORES, PHD; DAVID P. RUSSO, BA; CYNTHIA JIMENEZ, RN; BENARD R. RUBIN, DO Osteopathic physicians caring for patients with fibro- treatments for FM incorporate nonpharmacologic ap- myalgia syndrome (FM) often use osteopathic manipu- proaches such as OMT. lative treatment (OMT) in conjunction with other forms of (Key words: osteopathic manipulative treatment, standard medical care. Despite a growing body of evi- orthopedic manipulation, fibromyalgia, clinical trials) dence on the efficacy of manual therapy for the treatment of selected acute musculoskeletal conditions, the role of ibromyalgia (FM) syndrome is a common nonarticular, OMT in treating patients with chronic conditions such Frheumatic musculoskeletal pain disorder for which a as FM remains largely unknown. definite cause has yet to be identified.1 Diffuse muscu- Twenty-four female patients meeting American Col- loskeletal pain and aching, the presence of multiple tender lege of Rheumatology criteria for FM were randomly points (TP), disturbed sleep, fatigue, and morning stiffness assigned to one of four treatment groups: (1) manipulation characterize the syndrome. Central to the American College group, (2) manipulation and teaching group, (3) moist of Rheumatology’s FM diagnostic criteria are the presence of heat group, and (4) control group, which received no addi-