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1. What Pethidine Tablets Are and What They Are Used for 2. Before You

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1. What Pethidine Tablets Are and What They Are Used for 2. Before You 148x420 Layout 1/4/08 15:32 Page 1 148x420 Layout 1/4/08 15:32 Page 2 PACKAGE LEAFLET: INFORMATION FOR THE USER D05458 3. How to take Pethidine Tablets Reporting of side effects Always take this medicine exactly as your doctor If you get any side effects, talk to your doctor or Pethidine 50mg Tablets or pharmacist has told you. Check with your pharmacist or nurse. This includes any possible doctor or pharmacist if you are not sure. side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Pethidine Hydrochloride This medicine is for oral use. Scheme. Website: www.mhra.gov.uk/yellowcard Adults: or search for MHRA Yellow Card in the Google Read all of this leaflet carefully before you Other medicines which may interact with 1-3 tablets (50-150mg) as a single dose. This may Play or Apple App Store. By reporting side effects take this medicine because it contains Pethidine Tablets are: be repeated if the doctor decides this is needed you can help provide more information on the important information for you • medicines for sleeping problems (sedatives) but it should not be repeated more often than safety of this medicine. and anxiety, such as chloral, diazepam, and • Keep this leaflet. You may need to read it every four hours. 5. How to store Pethidine Tablets again. barbiturates • CNS depressants (drugs that act on the Elderly and infirm patients: Keep this medicine out of the sight and reach of • If you have any further questions, ask your 1 tablet (50mg). This may be repeated if the doctor or pharmacist. brain and make you feel drowsy or faint). children. These include sleeping pills, anti-histamines doctor decides this is needed but it should not • This medicine has been prescribed for you be repeated more often than every four hours. Do not use this product after the expiry date personally and you must not pass it onto (medicines used to treat allergies) that make you drowsy, medicines used to treat certain Your doctor may increase this to 2 or 3 tablets which is on the carton and blister pack. The others. It may harm them, even if their once your reaction to Pethidine is known. expiry date refers to the last day of that month. symptoms are the same as yours. mental disorders, other pain killers or a general • If you get any side effects, talk to your anaesthetic. Children: Store in the original packaging. Do not store doctor or pharmacist . This includes any • anaesthetics A single dose of 0.5-2mg/kg body weight. This above 25°C. possible side effects not listed in this leaflet. • mood stabilisers (drugs used to treat mental may be repeated if the doctor decides this is Medicines should not be disposed of via See section 4. disorders) e.g. chlorpromazine needed but it should not be repeated more wastewater or household waste. Ask your • mexiletine, a drug used to treat an irregular often than every four hours. pharmacist how to dispose of medicines no heartbeat If you forget to take Pethidine Tablets longer required. These measures will help to What is in this leaflet: • cimetidine, a drug used to treat stomach ulcers If you have missed a dose take it as soon as you protect the environment. • anticonvulsants (drugs used to stop fits), such 1. What Pethidine Tablets are and what they are used remember unless it is nearly time for your next as phenytoin. dose. Then continue your normal dose times. Do 6. Contents of the pack and other for • medicines used to treat feeling or being sick not take a double dose. information 2. Before you take Pethidine Tablets such as domperidone and metoclopramide What Pethidine Tablets contain: 3. How to take Pethidine Tablets • cisapride, a drug used to treat gastric reflux If you have taken more Pethidine Tablets than you should Active substance: Pethidine Hydrochloride 4. Possible side effects • alcohol 50mg per tablet. 5. How to store Pethidine Tablets • antibiotics (medicines used to treat bacterial If you take too much of your medicine seek immediate medical advice from your doctor or Other ingredients: starch, lactose, sucrose, talc, 6. Contents of the pack and other information infections), such as ciprofloxacin magnesium stearate and acacia. • duloxetine, a medicine used to treat your nearest hospital. Symptoms of an overdose 1. What Pethidine Tablets are and include shaking, fits, and sudden or unexpected What Pethidine Tablets look like and contents what they are used for depression • medicines used to treat depression known as difficulty in breathing. of the pack: Pethidine is an opioid analgesic with pain SSRIs, such as citalopram or paroxetine If you stop taking Pethidine Tablets The tablets are white, round and flat with relieving properties. This medicine is used for the • medicines used to treat depression known as You should not stop taking Pethidine Tablets bevelled edges. The have M50 marked on relief of moderate to severe pain including pain tricyclic antidepressants, such as amitriptyline until advised to do so by your doctor. If you stop one face and a break line on the other. They during labour and before and during operations. or clomipramine treatment too suddenly you may experience are supplied in cartons of 5 blister packs each 2. Before you take Pethidine Tablets • medicines used to treat anxiety known as symptoms of withdrawal such as stomach pains, containing 10 tablets. anxiolytics, such as diazepam or lorazepam feeling sick and feeling anxious. Your doctor will Marketing Authorisation Holder: You should not take Pethidine Tablets if: • carbamazepine, a medicine used to treat advise you how to stop your treatment with Martindale Pharma • you are allergic to Pethidine or any of the other epilepsy (fits) and bipolar disorder. Pethidine Tablets. Bampton Road ingredients of this medicine (listed in section Harold Hill 6) Concomitant use of Pethidine Tablets and 4. Possible side effects sedative medicines such as benzodiazepines or Romford Essex • you suffer from asthma, shallow breathing and Like all medicines, this medicine can cause side RM3 8UG other breathing difficulties related drugs increases the risk of drowsiness, effects although not everybody gets them. • you are taking or have taken within the difficulties in breathing (respiratory depression), Manufacturer: coma and may be life-threatening. Because of Tolerance, addiction and withdrawal Macarthys Laboratories Ltd last two weeks a type of drug used to treat Repeated use of pethidine can result in severe depression known as monoamine this, concomitant use should only be considered T/A Martindale Pharma when other treatment options are not possible. tolerance and addiction. Prolonged use of Bampton Road oxidase inhibitors (MAOI’s) (see ‘Taking other this medicine can result in mental and physical medicines’) However, if your doctor does prescribe Pethidine Harold Hill dependence on pethidine which may result Essex • you suffer from alcoholism together with sedative medicines the dose and in withdrawal symptoms if your treatment is • you are suffering from severe headaches or duration of concomitant treatment should be RM3 8UG stopped too quickly. The withdrawal symptoms United Kingdom have suffered a recent head injury (raised limited by your doctor. of Pethidine Tablets include sweating, anxiety, intracranial pressure) Please tell your doctor about all sedative difficulty sleeping, loss of appetite, pain, Product licence number: PL 00156/0031 • you have a tumour of the adrenal gland known medicines you are taking and follow your stomach cramps and diarrhoea. If you are as phaeochromocytoma This leaflet was last revised in: doctor’s dose recommendation closely. It could worried about this possible side effect please December 2020 • you suffer from a convulsive disorder (fits) such be helpful to inform friends or relatives to be talk to your doctor. as epilepsy aware of the signs and symptoms stated above. If you have been given Pethidine Tablets during • you suffer from a problem that could cause Contact your doctor when experiencing such your pregnancy your baby may experience paralysis of the small intestine (paralytic ileus) symptoms. • your kidneys or liver are not working properly withdrawal symptoms shortly after birth. • you are suffering from a condition known as Pregnancy, breast-feeding and fertility These symptoms include restlessness, jerking delirium tremens, caused by withdrawal from If you are pregnant or breast-feeding, think you or shaking, sweating, fever, unusually fast alcohol may be pregnant or are planning to have a baby, breathing, poor feeding and projectile vomiting. • you suffer from diabetes ask your doctor or pharmacist for advice before If you are concerned about the possible side using this medicine. effects this medicine may have on your unborn Pethidine Tablets should not be given to you if Pethidine Tablets should not be taken in the first child please talk to your doctor before being you are unconscious. given this medicine. Warnings and precautions three months of pregnancy unless your doctor Talk to your doctor or pharmacist before being considers their use to be essential. Serious side effects given Pethidine Tablets if Pethidine can pass into your baby either through If any of the following symptoms occur tell • your gall bladder is not working properly your blood (during pregnancy and labour) your doctor or nurse immediately. These are • you have an underactive thyroid gland or through your breast milk. This can cause symptoms of a serious allergic reaction. • you think you may be in shock, as there is a risk breathing problems in newborn babies. Your Not known (frequency cannot be estimated of coma doctor will be aware of this and will correct the from the available data): • you have a rapid heartbeat problem and discuss feeding with you. • sudden wheeziness and tightness of chest • you suffer from problems related to your Driving and using machines • swelling of eyelids, face or lips adrenal gland (the organ responsible for stress This medicine can affect your ability to drive • skin lumps or hives levels), including Addisons disease (an illness and operate machinery.
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