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PG Course Syllabus – FINAL

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PG Course Syllabus – FINAL postgraduate course Atlanta,Georgia october 23, 2014 1 2 Table of Contents MODULE 1: LIVER PRIMARY SCLEROSING CHOLANGITIS – Dennis Black MD ................................................................. 13 THE JAUNDICED INFANT ‐ Saul Karpen MD ....................................................................................... 25 ACUTE LIVER FAILURE – Estella Alonso MD ....................................................................................... 43 MODULE 2: ENDOSCOPY THE DREADED WAKE‐UP CALL (PART A) – Mercedes Martinez MD .................................................. 55 THE DREADED WAKE‐UP CALL (PART B) – Lee Bass MD .................................................................... 67 ENDOSCOPIC INTERVENTIONS FOR BILIARY TRACT DISEASE – Victor Fox MD .................................. 75 MODULE 3: GI POTPOURRI EXTRAESOPHAGEAL MANIFESTATIONS OF GER – Benjamin Gold MD .............................................. 86 EoE: PPI, EGD AND WHAT TO EAT: ALPHABET DISTRESS – Sandeep Gupta MD ............................... 105 SNEW TRICK AND TREATMENTS FOR MOTILITY DISORDERS – Carlo Di Lorenzo MD ........................ 116 DIAGNOSIS AND MANAGEMENT OF CONSTIPATION – Manu Sood MD ........................................... 130 MODULE 4: NUTRITION DIET AND THE MICROBIOME – Robert Baldassano MD .................................................................... 141 FODMAP: NAVIGATING THIS NOVEL DIET – Bruno Chumpitazi MD .................................................. 152 NUTRITION EIN TH CHILD WITH NEUROLOGICAL DISABILITIES – Kathleen Motil MD ...................... 162 MODULE 5: INTESTINAL INFLAMMATION EARLY ONSET INFLAMMATORY BOWEL DISEASE ‐ Scott Snapper MD .............................................. 170 “LUMINITIS”: WHEN INFLAMMATION IS NOT IBD – Robbyn Sockolow MD ..................................... 181 BEYOND ANTI‐TNF THERAPY: NEW MEDICATIONS IN THE PIPELINE – Athos Bousvaros MD ........... 190 NASPGHAN assumes no responsibility for any use or operation of any method, product, instruction, concept or idea contained in the material herein or for any injury or damage to persons or property (whether products liability, negligence or otherwise) resulting from such use or operation. The discussion, views, and recommendations as to medical procedures, choice of drugs and drug dosages herein are the sole responsibility of the authors. Because of rapid advances in the medical sciences, the Society cautions that independent verification should be made of diagnosis and drug dosages. The reader is solely responsible for the conduct of any suggested test or procedure. Some of the slides reproduced in this syllabus contain animation in the power point version. This cannot be seen in the printed version. 4 Faculty NASPGHAN POSTGRADUATE COURSE Course Directors: Melanie Greifer MD Assistant Professor of Pediatrics Hofstra North Shore‐LIJ School of Medicine Pediatric Gastroenterology and Nutrition Cohen Children's Medical Center of New York New Hyde Park, New York Jennifer Strople MD Assistant Professor of Pediatrics Northwestern University Feinberg School of Medicine Clinical Director, Inflammatory Bowel Disease Program Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL Faculty: Estella M Alonso MD Dennis D Black MD Professor of Pediatrics J. D. Buckman Professor of Pediatrics Northwestern University Feinberg School of Professor of Physiology Medicine University of Tennessee Health Science Center Medical Director of Hepatology and Liver Director, Children’s Foundation Research Institute Transplantation Le Bonheur Children’s Hospital Ann & Robert H. Lurie Children’s Hospital of Chicago Memphis, TN Chicago, IL Athos Bousvaros MD, MPH Robert N Baldassano MD Associate Professor of Pediatrics Professor of Pediatrics, University of Associate Director, IBD Center Pennsylvania, Perelman School of Medicine Boston Children's Hospital Colman Family Chair in Pediatric Inflammatory Bowel Boston, MA Disease Director, Center for Pediatric Inflammatory Bowel Bruno P Chumpitazi MD, MPH Disease Director, Neurogastroenterology and Motility Children's Hospital of Philadelphia Program Philadelphia, PA Texas Children’s Hospital Assistant Professor of Pediatrics Lee Bass MD Baylor College of Medicine Assistant Professor of Pediatrics Houston, TX Director of Endoscopy/Clinical Practice Director Division of Gastroenterology, Hepatology and Carlo Di Lorenzo MD Nutrition Chief, Division of Pediatric Gastroenterology, Ann & Robert H. Lurie Children's Hospital of Chicago Hepatology and Nutrition Northwestern University Feinberg School of Nationwide Children's Hospital Medicine Professor of Clinical Pediatrics Chicago, IL The Ohio State University College of Medicine Columbus, OH 5 Victor L Fox MD Kathleen J Motil MD PhD Associate Professor of Pediatrics Professor of Pediatrics Harvard Medical School USDA/ARS Children’s Nutrition Research Center Director, GI Procedure and Endoscopy Unit, Baylor College of Medicine and Pediatric Polyposis Program Pediatric Gastroenterology, Hepatology, and Division of Gastroenterology, Hepatology, and Nutrition Nutrition Texas Children’s Hospital Boston Children's Hospital Houston, Texas Boston, MA Scott B Snapper MD, PhD Jason Frischer MD Wolpow Family Chair in IBD Treatment and Research Director, Peña Colorectal Center Director, Inflammatory Bowel Disease Center and Director, Extracorporeal Membrane Oxygenation Basic & Translational Research (Gastroenterology, (ECMO) Program Children’s Hospital) Division of Pediatric General and Thoracic Surgery Director, Inflammatory Bowel Disease Research Assistant Professor, UC Department of Surgery (Gastroenterology, Brigham and Women’s Hospital) Cincinnati Children's Hospital Medical Center Associate Professor of Medicine, Harvard Medical Cincinnati, OH School Boston, MA Benjamin D Gold MD Children’s Center for Digestive Healthcare LLC Robbyn Sockolow MD GI Care for Kids, LLC Associate Professor of Clinical Pediatrics Staff Physician, Gastroenterology Weill Cornell Medical College Children’s Healthcare of Atlanta Director of Pediatric Gastroenterology and Nutrition Adjunct Professor, Emory University School of New York‐Presbyterian Hospital Medicine New York, NY Atlanta, GA Manu Raj Sood MD Sandeep Gupta MD Chief, Division of Pediatric Gastroenterology, Professor of Clinical Pediatrics and Clinical Medicine Hepatology and Nutrition Pediatric Gastroenterology, Hepatology and Children's Hospital of Wisconsin Nutrition Professor of Pediatrics Riley Hospital for Children, Indiana University Medical College of Wisconsin Indianapolis, IN Milwaukee, WI Saul Karpen MD PhD Raymond F. Schinazi Distinguished Biomedical Chair Professor of Pediatrics Division Chief, Pediatric Gastroenterology, Hepatology and Nutrition Emory University School of Medicine Children's Healthcare of Atlanta Atlanta, GA Mercedes Martinez MD Assistant Professor of Pediatrics Center for Liver Disease and Transplantation New York Presbyterian Hospital Columbia University New York, NY 6 Continuing Medical Education NASPGHAN CME Mission Statement The education mission of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition is to: 1) Advance understanding of normal development, physiology and pathophysiology of diseases of the gastrointestinal tract, liver and nutrition in children 2) Improve professional competence, quality of care, and patient outcomes by disseminating knowledge through scientific meetings, professional and public education. Our activities, education, and interventions will strive to use Adult Learning Methods (ALM) designed to improve competence, practice performance, and patient outcomes in measurable ways. These educational activities will be targeted to board certified or board eligible pediatric gastroenterologists, physicians with an expertise in pediatric gastroenterology, hepatology and nutrition, subspecialty fellows in pediatric gastroenterology, and nurses specializing in pediatric gastroenterology, hepatology and nutrition." Physicians The North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. AMA PRA Statement NASPGHAN designates this educational activity for a maximum of 8.25 AMA PRA Category 1 Credit(s)TM Physicians should only claim credit commensurate with the extent of their participation in the activity. 7 NASPGHAN POSTGRADUATE COURSE THURSDAY OCTOBER 23, 2014 Grand Ballroom, Atlanta Hilton 7:55 AM ‐ 8:00 AM WELCOME AND INTRODUCTION 8:00 AM – 9:15 AM MODULE 1: LIVER Moderators: Henry Lin MD and Jennifer Strople MD PRIMARY SCLEROSING CHOLANGITIS Dennis Black MD, Le Bonheur Children’s Hospital Learning objectives: Learn the etiology and progression of the condition Understand how to appropriately screen Review the treatment controversies, including ursodiol and vancomycin THE JAUNDICED INFANT Saul J Karpen MD, PhD, Emory University School of Medicine Learning objectives: • Learn the differential diagnosis and most common etiologies • Understand the impact of genetic testing and other diagnostic modalities • Know the available treatments and what is being developed ACUTE LIVER FAILURE Estella Alonso MD, Ann and Robert H Lurie Children’s Hospital of Chicago Learning objectives: Learn the differential diagnosis and most common etiologies Know the treatment options and algorithms Understand the time frame of referral for transplantation 9:00 AM – 9:15 AM
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