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84 November 2008 Produced by NHS Tayside Drug and Therapeutics Committee Medicines Advisory Group (MAG)

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84 November 2008 Produced by NHS Tayside Drug and Therapeutics Committee Medicines Advisory Group (MAG) TAYSIDE PRESCRIBER Tayside DTC Supplement No 84 November 2008 Produced by NHS Tayside Drug and Therapeutics Committee Medicines Advisory Group (MAG) SMC Advice issued in November 2008 Medicine Indication Local recommendation Comments and useful category links Ambrisentan tablets Treatment of patients with class Restricted for use within SMC advice (Volibris®) II and III pulmonary arterial national treatment centre SPC link hypertension to improve exercise capacity Anidulafungin powder and Treatment of invasive Pending AMG decision SMC advice solvent (Ecalta®) - candidiasis in adult non- SPC link Resubmission neutropenic patients Bosentan film-coated tablets Class II pulmonary arterial Not recommended SMC advice (Tracleer®) - hypertension Bosentan was previously Non submission accepted in 2003 for restricted use in grade III pulmonary arterial hypertension Icatibant solution for Symptomatic treatment of acute Not recommended SMC advice subcutaneous injection attacks of hereditary (Firazyr®) angioedema in adults Insulin glulisine solution for Treatment of adolescents and Non-formulary SMC advice subcutaneous injection children, 6 years or older with SPC link (Apidra®) - Abbreviated diabetes mellitus where a short Diabetes Handbook submission acting insulin analogue is appropriate Insulin lispro solution for Adults and children with Non-formulary SMC advice injection (Humalog® diabetes mellitus SPC link KwikPen) - Diabetes Handbook Abbreviated submission Insulin lispro (Humalog® Patients with diabetes mellitus, Non-formulary SMC advice Mix25 KwikPen) and for whom treatment with this SPC link insulin lispro (Humalog® biphasic insulin analogue is Diabetes Handbook Mix50 KwikPen) – appropriate. Abbreviated submission Quetiapine prolonged- Treatment of schizophrenia and Formulary (Schizophrenia) SMC advice release tablet (Seroquel manic episodes associated with under the direction of a SPC link XL®) - bipolar disorder specialist Abbreviated submission Rufinamide tablets Adjunctive therapy in the HOSPITAL ONLY SMC advice (Inovelon®) – treatment of seizures associated Paediatric neurology SPC link Resubmission with Lennox-Gastaut syndrome department To be monitored in epilepsy in patients four years and older clinic Click here for November SMC briefing note 1 TAPG Update TAPG section Drug(s)/topic Changes 4 Central Nervous Quetiapine Added for treatment of schizophrenia under the direction of a System prolonged-release psychiatrist to section 4.2. tablets* Antimuscarinic drugs Prescribing information for procyclidine and orphenadrine now listed in section 4.9. Previously in section 4.2. * SMC accepted medicine Forthcoming SMC Advice Local implementation of SMC recommendations is taken forward by the Tayside Medicines Governance Unit This bulletin is based on evidence available to the Tayside Medicines Governance Unit at time of publication and is covered by the Disclaimer and Terms & Conditions of use and access to the NHS Tayside Drug and Therapeutics Committee website (www.nhstaysideadtc.scot.nhs.uk). 2 .
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