Public Comment on Synthetic Cathinones, Tetrahydrocannabinol (THC), and Synthetic Cannabinoids Dear Judge Pryor
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Drug and Alcohol Prevention Programs Annual Notification
MCCCD DRUG AND ALCOHOL PREVENTION PROGRAMS ANNUAL NOTIFICATION STATEMENT ON DRUG-FREE CAMPUSES In accordance with the Drug-Free Schools and Communities Act Amendments of 1989 (Act), the Maricopa County Community College District (MCCCD) is distributing this notification to all students and employees to inform them of MCCCD’s comprehensive program to prevent the use of illicit drugs and the abuse of alcohol. This notification summarizes MCCCD’s programs, resources, policies, and standards of conduct; discusses health risks; highlights treatment options; and provides an overview of sanctions. STANDARDS OF CONDUCT It is the goal and policy of Maricopa County Community College District to provide a drug-free environment for all college students and employees. To achieve this goal and to comply with federal law, MCCCD prohibits the unlawful sale, distribution, dispensation, possession, and use of controlled substances on MCCCD property or as part of any of its programs and/or activities. Students, faculty, staff and visitors of any MCCCD campus are advised to become familiar with federal, state and local laws regarding alcohol and other drugs in accordance with the campus location. Students, faculty, staff, and visitors on any MCCCD campus must: 1) abide by MCCCD policies regarding alcohol abuse and illicit drugs; 2) abide by local, state and federal laws regarding alcohol, drugs, and controlled substances; and 3) act to reduce the risks associated with the use and abuse of these substances. MCCCD students and employees are subject to all applicable drug and alcohol policies including, but not limited to: AR 2.4.7 – Abuse-Free Environment AR 4.13 – Use of Alcoholic Beverages See also the Auxiliary Services section for Tobacco-Free Environment and the Appendices/Student Section Medical Marijuana Act of the Administrative Regulations. -
House Bill No. 2191
SECOND REGULAR SESSION HOUSE BILL NO. 2191 99TH GENERAL ASSEMBLY INTRODUCED BY REPRESENTATIVE QUADE. 5582H.01I D. ADAM CRUMBLISS, Chief Clerk AN ACT To repeal section 579.060, RSMo, and to enact in lieu thereof one new section relating to controlled substances, with penalty provisions. Be it enacted by the General Assembly of the state of Missouri, as follows: Section A. Section 579.060, RSMo, is repealed and one new section enacted in lieu 2 thereof, to be known as section 579.060, to read as follows: 579.060. 1. A person commits the offense of unlawful sale, distribution, or purchase of 2 over-the-counter methamphetamine precursor drugs if he or she knowingly: 3 (1) Sells, distributes, dispenses, or otherwise provides any number of packages of any 4 drug product containing detectable amounts of ephedrine, levomethamphetamine, 5 phenylpropanolamine, propylhexedrine, or pseudoephedrine, or any of their salts, optical 6 isomers, or salts of optical isomers, in a total amount greater than nine grams to the same 7 individual within a thirty-day period, unless the amount is dispensed, sold, or distributed 8 pursuant to a valid prescription; or 9 (2) Purchases, receives, or otherwise acquires within a thirty-day period any number of 10 packages of any drug product containing any detectable amount of ephedrine, 11 levomethamphetamine, phenylpropanolamine, propylhexedrine, or pseudoephedrine, or any 12 of their salts or optical isomers, or salts of optical isomers in a total amount greater than nine 13 grams, without regard to the number of transactions, unless the amount is purchased, received, 14 or acquired pursuant to a valid prescription; or 15 (3) Purchases, receives, or otherwise acquires within a twenty-four-hour period any 16 number of packages of any drug product containing any detectable amount of ephedrine, 17 levomethamphetamine, phenylpropanolamine, propylhexedrine, or pseudoephedrine, or any EXPLANATION — Matter enclosed in bold-faced brackets [thus] in the above bill is not enacted and is intended to be omitted from the law. -
Bath Salts and Synthetic Marijuana: an Emerging Threat by Rommie L
Continuing Education Course Bath Salts and Synthetic Marijuana: An Emerging Threat BY ROMMIE L. DUCKWORTH TRAINING THE FIRE SERVICE FOR 135 YEARS To earn continuing education credits, you must successfully complete the course examination. The cost for this CE exam is $25.00. For group rates, call (973) 251-5055. Bath Salts and Synthetic Marijuana: An Emerging Threat Educational Objectives On completion of this course, students will 1) Define the term “Designer Drug”. 3) Determine what constitutes Bath Salts, and their effects. 2) Learn how regulation is not inhibiting the production of 4) Determine what constitutes Synthetic Marijuana, and its designer drugs. effects BY ROMMIE L. DUCKWORTH emergency responders, and healthcare providers. Designer drugs are chemical compounds that are newly created, modi- April 5, 2011. Spanaway, Washington: Medic and Army Ser- fied, or repurposed to provide abusers with effects similar to geant Dave Stewart, high on bath salts bought at a local pipe currently illegal recreational drugs. They are often relatively shop, killed himself and his wife during a police pursuit. Their five-year-old son was also found dead in the car. easy to make and, because of their ever-changing ingredient list, are also extremely difficult to regulate. August 21, 2011. Bowling Green, Kentucky: Teenager Ashley The term “designer drugs” originated in the 1980s, but Stillwell became paralyzed while smoking 7H, a form of syn- the idea of marketing legal chemical combinations related thetic marijuana, with her friends. She lay on the floor, helpless, to regulated or banned drugs dates back to the 1920s. Such as her friends discussed what to do, including how to dispose of her body. -
The Stimulants and Hallucinogens Under Consideration: a Brief Overview of Their Chemistry and Pharmacology
Drug and Alcohol Dependence, 17 (1986) 107-118 107 Elsevier Scientific Publishers Ireland Ltd. THE STIMULANTS AND HALLUCINOGENS UNDER CONSIDERATION: A BRIEF OVERVIEW OF THEIR CHEMISTRY AND PHARMACOLOGY LOUIS S. HARRIS Dcparlmcnl of Pharmacology, Medical College of Virginia, Virginia Commonwealth Unwersity, Richmond, VA 23298 (U.S.A.) SUMMARY The substances under review are a heterogenous set of compounds from a pharmacological point of view, though many have a common phenylethyl- amine structure. Variations in structure lead to marked changes in potency and characteristic action. The introductory material presented here is meant to provide a set of chemical and pharmacological highlights of the 28 substances under con- sideration. The most commonly used names or INN names, Chemical Abstract (CA) names and numbers, and elemental formulae are provided in the accompanying figures. This provides both some basic information on the substances and a starting point for the more detailed information that follows in the individual papers by contributors to the symposium. Key words: Stimulants, their chemistry and pharmacology - Hallucinogens, their chemistry and pharmacology INTRODUCTION Cathine (Fig. 1) is one of the active principles of khat (Catha edulis). The structure has two asymmetric centers and exists as two geometric isomers, each of which has been resolved into its optical isomers. In the plant it exists as d-nor-pseudoephedrine. It is a typical sympathomimetic amine with a strong component of amphetamine-like activity. The racemic mixture is known generically in this country and others as phenylpropanolamine (dl- norephedrine). It is widely available as an over-the-counter (OTC) anti- appetite agent and nasal decongestant. -
3,4-Methylenedioxymethcathinone (Methylone) [“Bath Salt,” Bk-MDMA, MDMC, MDMCAT, “Explosion,” “Ease,” “Molly”] December 2019
Drug Enforcement Administration Diversion Control Division Drug & Chemical Evaluation Section 3,4-Methylenedioxymethcathinone (Methylone) [“Bath salt,” bk-MDMA, MDMC, MDMCAT, “Explosion,” “Ease,” “Molly”] December 2019 Introduction: discriminate DOM from saline. 3,4-Methylenedioxymethcathinone (methylone) is a Because of the structural and pharmacological similarities designer drug of the phenethylamine class. Methylone is a between methylone and MDMA, the psychoactive effects, adverse synthetic cathinone with substantial chemical, structural, and health risks, and signs of intoxication resulting from methylone pharmacological similarities to 3,4-methylenedioxymeth- abuse are likely to be similar to those of MDMA. Several chat amphetamine (MDMA, ecstasy). Animal studies indicate that rooms discussed pleasant and positive effects of methylone when methylone has MDMA-like and (+)-amphetamine-like used for recreational purpose. behavioral effects. When combined with mephedrone, a controlled schedule I substance, the combination is called User Population: “bubbles.” Other names are given in the above title. Methylone, like other synthetic cathinones, is a recreational drug that emerged on the United States’ illicit drug market in 2009. It is perceived as being a ‘legal’ alternative to drugs of Licit Uses: Methylone is not approved for medical use in the United abuse like MDMA, methamphetamine, and cocaine. Evidence States. indicates that youths and young adults are the primary users of synthetic cathinone substances which include methylone. However, older adults also have been identified as users of these Chemistry: substances. O H O N CH3 Illicit Distribution: CH O 3 Law enforcement has encountered methylone in the United States as well as in several countries including the Netherlands, Methylone United Kingdom, Japan, and Sweden. -
(19) United States (12) Patent Application Publication (10) Pub
US 20130289061A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2013/0289061 A1 Bhide et al. (43) Pub. Date: Oct. 31, 2013 (54) METHODS AND COMPOSITIONS TO Publication Classi?cation PREVENT ADDICTION (51) Int. Cl. (71) Applicant: The General Hospital Corporation, A61K 31/485 (2006-01) Boston’ MA (Us) A61K 31/4458 (2006.01) (52) U.S. Cl. (72) Inventors: Pradeep G. Bhide; Peabody, MA (US); CPC """"" " A61K31/485 (201301); ‘4161223011? Jmm‘“ Zhu’ Ansm’ MA. (Us); USPC ......... .. 514/282; 514/317; 514/654; 514/618; Thomas J. Spencer; Carhsle; MA (US); 514/279 Joseph Biederman; Brookline; MA (Us) (57) ABSTRACT Disclosed herein is a method of reducing or preventing the development of aversion to a CNS stimulant in a subject (21) App1_ NO_; 13/924,815 comprising; administering a therapeutic amount of the neu rological stimulant and administering an antagonist of the kappa opioid receptor; to thereby reduce or prevent the devel - . opment of aversion to the CNS stimulant in the subject. Also (22) Flled' Jun‘ 24’ 2013 disclosed is a method of reducing or preventing the develop ment of addiction to a CNS stimulant in a subj ect; comprising; _ _ administering the CNS stimulant and administering a mu Related U‘s‘ Apphcatlon Data opioid receptor antagonist to thereby reduce or prevent the (63) Continuation of application NO 13/389,959, ?led on development of addiction to the CNS stimulant in the subject. Apt 27’ 2012’ ?led as application NO_ PCT/US2010/ Also disclosed are pharmaceutical compositions comprising 045486 on Aug' 13 2010' a central nervous system stimulant and an opioid receptor ’ antagonist. -
Synthetic Cathinones ("Bath Salts")
Synthetic Cathinones ("Bath Salts") What are synthetic cathinones? Synthetic cathinones, more commonly known as "bath salts," are synthetic (human- made) drugs chemically related to cathinone, a stimulant found in the khat plant. Khat is a shrub grown in East Africa and southern Arabia, and people sometimes chew its leaves for their mild stimulant effects. Synthetic variants of cathinone can be much stronger than the natural product and, in some cases, very dangerous (Baumann, 2014). In Name Only Synthetic cathinone products Synthetic cathinones are marketed as cheap marketed as "bath salts" should substitutes for other stimulants such as not be confused with products methamphetamine and cocaine, and products such as Epsom salts that people sold as Molly (MDMA) often contain synthetic use during bathing. These cathinones instead (s ee "Synthetic Cathinones bathing products have no mind- and Molly" on page 3). altering ingredients. Synthetic cathinones usually take the form of a white or brown crystal-like powder and are sold in small plastic or foil packages labeled "not for human consumption." Also sometimes labeled as "plant food," "jewelry cleaner," or "phone screen cleaner," people can buy them online and in drug paraphernalia stores under a variety of brand names, which include: Flakka Bloom Cloud Nine Lunar Wave Vanilla Sky White Lightning Scarface Image courtesy of www.dea.gov/pr/multimedia- library/image-gallery/bath-salts/bath-salts04.jpg Synthetic Cathinones • January 2016 • Page 1 How do people use synthetic cathinones? People typically swallow, snort, smoke, or inject synthetic cathinones. How do synthetic cathinones affect the brain? Much is still unknown about how synthetic cathinones affect the human brain. -
Alcohol Consuming Energy Drinks Mixed with Alcohol Results in an Increase in the Number of Alcohol-Related Injuries Because the Perception of Impairment Is Diminished
® DRUG FACT SHEET Alcohol Consuming energy drinks mixed with alcohol results in an increase in the number of alcohol-related injuries because the perception of impairment is diminished. Class of drug: Depressant Main active ingredient: Ethanol/Ethyl alcohol, which is made by fermenting or distilling grains, fruit and vegetables, is the main ingredient. Alcohol is found in beverages like beer, wine, coolers and hard liquor like rum and vodka. What it looks like: Liquid, either clear or colored A standard drink is equal to .6 oz of pure alcohol, which is equal to 12 oz of beer, Street names: Booze, Juice, Spirits, Brew, Sauce 8 oz of malt liquor, 5 oz of wine and 1.5 oz or a “shot” of 80-proof liquor (e.g. gin, How it is used: Taken orally rum, vodka). Duration of high: Effects of high can last from one to four hours. The effect of alcohol on the body by volume is the same. It is the amount of ethanol consumed that affects a person most, not the type of alcoholic drink. Withdrawal symptoms: Restlessness, sweating, tremors, insomnia, anxiety, c onvulsions, death Detected in the body: With a healthy liver, an average person can New York information eliminate one drink (.6 oz of alcohol) per hour. In 2011, 19 percent of high Detection time in urine is one to two days. school students in New York re - Effects: Physical —small amounts can produce relaxed ported that they drank alcohol muscles, headache, nausea; somewhat large for the first time before the age amounts can cause slurred speech, double vision; very large amounts can cause respiratory of 13. -
10.30.19 Didactic
STIMULANTS PART II Michael H. Baumann, Ph.D. Designer Drug Research Unit (DDRU), Intramural Research Program, NIDA, NIH Baltimore, MD 21224 Chronology of Stimulant Misuse 1. 2000s: Methamphetamine 2. 2010s: Bath Salts 3. Summary 2 Topics Covered for Each Substance Chemistry Formulations and Methods of Use Pharmacokinetics and Metabolism Desired and Adverse Effects Chronic and Withdrawal Effects Neurobiology Treatments 2000s: Methamphetamine Methamphetamine, a synthetic stimulant 5 Formulations and Methods of Use Methamphetamine (i.e., Ice or Crystal) Smoking using pipes Methamphetamine HCl Intravenous injection of solutions using needle and syringe Intranasal snorting of crystals Pharmacokinetics and Metabolism Pharmacokinetics Smoked and intravenous drugs reach brain within seconds Intranasal drug reaches brain within minutes Much longer half-life than cocaine Metabolism N-demethylation to form amphetamine (bioactive) Hydroxylation to form inactive metabolites Desired Effects Enhanced Mood and Euphoria Increased Attention and Alertness Decreased Need for Sleep Appetite Suppression Sexual Arousal Adverse Effects Psychosis Arrhythmias, Palpitations, Heart Attack Hypertension, Stroke Hyperthermia, Rhabdomyolysis Multisystem Organ Failure 11 www.facesofmeth.us. “METH Mouth” 12 Molecular Sites of Action SLC6 Monoamine Transporters Dopamine transporter (DAT) Norepinephrine transporter (NET) 5-HT transporter (SERT) Other sites Vesicular Monoamine Transporter 2 (VMAT2) Trace amine-associated receptors (TAAR1) -
Getting Through Amphetamine Withdrawal – a Guide for People
Amphetamine_wdl_220404.qxd 28/04/2004 12:19 PM Page i GETTING THROUGH AMPHETAMINE WITHDRAWAL A guide for people trying to stop amphetamine use Amphetamine_wdl_220404.qxd 28/04/2004 12:19 PM Page ii GETTING THROUGH AMPHETAMINE WITHDRAWAL CONTENTS About this book x Making the decision to stop using amphetamines x Amphetamine withdrawal x What is withdrawal? x How long will the symptoms last? What kinds of symptoms will I have? x Getting started x Organise a safe environment x Organise support x Structure your day x The role of medication x Getting through withdrawal x Cravings x Sleep x September 1996 Relaxing x Revised May 2004 Mood swings x © Turning Point Alcohol and Drug Centre Inc. Strange thoughts x 54-62 Gertrude Street, Fitzroy VIC 3065 Eating again x T: 03 8413 8413 Aches and pains x F: 03 9416 3420 High-risk situations x Counselling x E: [email protected] It’s all too much x www.turningpoint.org.au Sex and withdrawal x Original edition by Dr Nik Lintzeris, Dr Adrian Dunlop and After withdrawal x David Thornton What next? x Updated (2004) by Dr Adrian Dunlop, Sandra Hocking, Dr Getting back on track if you ‘slip up’ x Nicole Lee and Peter Muhleisen Notes for supporters x Cartoonist: Mal Doreian Useful contact numbers x ISBN 0_958 6979_1_4 1 Amphetamine_wdl_220404.qxd 28/04/2004 12:19 PM Page 2 GETTING THROUGH AMPHETAMINE WITHDRAWAL MAKING THE DECISION TO STOP USING AMPHEATMINES ABOUT THIS BOOK This book is written for people who are thinking about You may find it helpful to make a list of the positives and the or trying to stop using amphetamines, even if just for a negatives about using amphetamines. -
What Is Cocaine?
WHAT IS COCAINE? AN EDUCATIONAL FACT SHEET FROM THE FLORIDA ALCOHOL & DRUG ABUSE ASSOCIATION Cocaine is a powerful central nervous sys- OTHER WAYS OF USING COCAINE tem stimulant that comes from the South Ameri- The most dangerous form of smokable cocaine can coca bush. The cocaine (cocaine hydrochlo- is coca paste made by using gasoline or sulfuric acid ride) most commonly used in the U.S. is a white to extract a smokable paste. The paste is dried and crystalline powder extracted from coca leaves. smoked in a pipe or crushed into a cigarette. The cocaine bought on the street is a mixture of pure cocaine and other substances such as talc, Cocaine may be used with other drugs to pro- flour, laxatives, sugar, local anesthetics and other duce a variety of effects. “Speedballing” is the com- stimulants or powders that are added to stretch bination of cocaine and heroin in a syringe for in- the supply and increase the seller’s profit. jection. “Spaceballing” is the sprinkling of liquid Users buy powdered cocaine in grams (1/ PCP (Phencyclidine) on crack cocaine before smok- 28 of an ounce) or in fractions of a gram called ing. “Champagne” is the combination of cocaine and “quarters” or “eighths.” Often, cocaine is snorted marijuana. through the nose. Razor blades are used to crush any large rocks or particles of cocaine and to form “lines” that make snorting easier. Some SHORT-TERM EFFECTS users inject cocaine into a muscle or vein; others When cocaine is snorted, the effects begin convert it into a smokable form called freebase. -
Dangerous New Street Drug Cocktail
Ashly Custer City of Rio Grande City Public Relations Cell: (956)257-1027 Email: [email protected] PUBLIC NOTICE/WARNING: DANGEROUS NEW STREET DRUG COCKTAIL The Rio Grande City Police Department has received information that street level drug dealers are mixing crack cocaine with methamphetamine and passing it off as regular crack cocaine. This is a deadly mix for any user since most of the time have no idea what they are smoking. We encourage our community to get involved in the fight against drugs and report any location they believe is selling narcotics. METHAMPHETAMINE Meth, or methamphetamine, is an intense and highly addictive stimulant that is commonly snorted, smoked, or injected directly into one’s veins. Those taking meth typically want a fast or even instant high, the effects peak in 1-15 minutes and generally last 4-8 hours. Unfortunately, ingesting any kind of drugs via these methods is both dangerous and damaging to one’s health. Considering how devastating meth is in any form, these risks are very serious for meth users and have resulted in many deaths. According to new research from Toronto's Centre for Addiction and Mental Health (CAMH), researchers found that people who regularly abuse meth are an average of 4.67 times more likely to die than those who do not use drugs. CRACK COCAINE In addition to the usual risks associated with cocaine use, crack users may experience severe respiratory problems, including coughing, shortness of breath, lung damage and bleeding. Long-term effects from use of crack cocaine include severe damage to the heart, liver and kidneys.