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IX Updating Course of Antimicrobials and Infectious Diseases REVISTA ESPAÑOLA DE QQuimioterapiauimioterapia SPANISH JOURNAL OF CHEMOTHERAPY ISSN: 0214-3429 Volume 32 Supplement number 2 September 2019 Pages: 01-79 IX Updating Course of Antimicrobials and Infectious Diseases Coordination: Dr. FJ. Candel González Servicio de Microbiologia Clínica Hospital Clínico San Carlos Madrid. Spain. 18 y 19 de febrero de 2019 Auditorio San Carlos. Pabellón Docente Publicación Oficial Hospital Clínico San Carlos de la Sociedad Española de Quimioterapia REVISTA ESPAÑOLA DE Quimioterapia Revista Española de Quimioterapia tiene un carácter multidisciplinar y está dirigida a todos aquellos profesionales involucrados en la epidemiología, diagnóstico, clínica y tratamiento de las enfermedades infecciosas Fundada en 1988 por la Sociedad Española de Quimioterapia Sociedad Española de Quimioterapia Indexada en Publicidad y Suscripciones Publicación que cumple los requisitos de Science Citation Index Sociedad Española de Quimioterapia soporte válido Expanded (SCI), Dpto. de Microbiología Index Medicus (MEDLINE), Facultad de Medicina ISSN Excerpta Medica/EMBASE, Avda. Complutense, s/n 0214-3429 Índice Médico Español (IME), 28040 Madrid Índice Bibliográfico en Ciencias e-ISSN de la Salud (IBECS) 1988-9518 Atención al cliente Depósito Legal Secretaría técnica Teléfono 91 394 15 12 M-32320-2012 Dpto. de Microbiología Correo electrónico Facultad de Medicina [email protected] Maquetación Avda. Complutense, s/n Kumisai 28040 Madrid [email protected] Consulte nuestra página web Impresión Disponible en Internet: www.seq.es España www.seq.es Esta publicación se imprime en papel no ácido. This publication is printed in acid free paper. LOPD Informamos a los lectores que, según lo previsto © Copyright 2019 en el Reglamento General de Protección Sociedad Española de de Datos (RGPD) 2016/679 del Parlamento Quimioterapia Europeo, sus datos personales forman parte de la base de datos de la Sociedad Española de Reservados todos los derechos. Quimioterapia (si es usted socio) Queda rigurosamente prohibida, sin la autorización escrita del Si desea realizar cualquier rectificación o editor, la reproducción parcial cancelación de los mismos, deberá enviar una o total de esta publicación solicitud por e-mail a la Sociedad Española de por cualquier medio o Quimioterapia ([email protected]) procedimiento, comprendidos la reprografía y el tratamiento informático, y la distribución de ejemplares mediante alquiler o préstamo públicos, bajo las sanciones establecidas por la ley REVISTA ESPAÑOLA DE Quimioterapia Director Secretario de Redacción J. Barberán López Luis Alou Cervera Comité Editorial F. Álvarez Lerma (Barcelona) J. Mensa Pueyo (Barcelona) F. Baquero Mochales (Madrid) J. J. Picazo de la Garza (Madrid) E. Bouza Santiago (Madrid) J. Prieto Prieto (Madrid) J. A. García Rodríguez (Salamanca) B. Regueiro García (Santiago de Compostela) M. Gobernado Serrano (Valencia) A. Torres Martí (Barcelona) Consejo Editorial L. Aguilar (Madrid) J. Fortún (Madrid) M. Ortega (Barcelona) J. I. Alós (Madrid) J. J. Gamazo (Vizcaya) J. Oteo (Madrid) J. R. Azanza (Pamplona) E. García Sánchez (Salamanca) J. A. Oteo (Logroño) J. Aragón (Las Palmas de Gran Canaria) I. García García (Salamanca) E. Palencia Herrejón (Madrid) A. Artero (Valencia) J. E. García Sánchez (Salamanca) A. Pascual Hernández (Sevilla) V. Asensi (Oviedo) E. García Vázquez (Murcia) J. Pasquau (Sevilla) G. Barbeito (Santiago de Compostela) J. Gómez Gómez (Murcia) J. Pemán (Valencia) J. M. Barbero (Madrid) M. L. Gómez-Lus (Madrid) J. L Pérez-Arellano (Las Palmas) J. Campos (Madrid) J. González del Castillo (Madrid) B. Pérez-Gorricho (Madrid) F.J. Candel (Madrid) F. González Romo (Madrid) A. Ramos (Madrid) E. Cantón (Valencia) J. J. Granizo (Madrid) J. M. Ramos (Alicante) R. Cantón (Madrid) S. Grau (Barcelona) J. Reina (Palma de Mallorca) J. A. Capdevila Morell J.M. Guardiola (Barcelona) M. A. Ripoll (Ávila) (Barcelona) J. Guinea (Madrid) I. Rodriguez-Avial (Madrid) M. Casal (Córdoba) X. Guirao (Barcelona) M. Ruiz (Alicante) J. Castillo (Zaragoza) J. Gutiérrez (Granada) F. Cobo (Granada) J. B. Gutiérrez (Córdoba) M. Sabriá (Barcelona) J. Cobo Reinoso (Madrid) B. Isidoro (Madrid) M. Salavert (Valencia) N. Cobos (Madrid) P. Llinares (La Coruña) B. Sánchez Artola (Madrid) J. L. del Pozo (Navarra) J. E. Losa Garcia (Madrid) M. Segovia (Murcia) R. De la Cámara (Madrid) J. R. Maestre Vera (Madrid) R. Serrano (Madrid) C. De la Calle (Barcelona) L. Martínez Martínez (Córdoba) D. Sevillano (Madrid) M. Dominguez-Gil (Valladolid) E. Maseda (Madrid) A. Suárez (Madrid) J. Eiros (Valladolid) R. Menéndez (Valencia) A. Tenorio (Huelva) P. Escribano (Madrid) P. Merino (Madrid)) A. Torres (Murcia) A. Estella (Cádiz) P. Muñoz (Madrid) C. Vallejo (Oviedo) M. C. Fariñas Álvarez (Santander) J. L. Muñoz Bellido (Salamanca) J. Vila (Barcelona) C. Fariñas (Santander) V. Navarro (Alicante) J. Yuste (Madrid) Contents REVISTA ESPAÑOLA DE uimioterapia Volume 32 Supplement number 2 Q September 2019 Introduction Update in Infectious Diseases 2019 01 Francisco Javier Candel, Carla Margarita Rico, Irene Díaz De La Torre, Berta Laguna, Jorge Martínez- Jordán, Sara Medrano, Mauricio César Escobar-Porcel, Angel López-Delgado, Laura López-González, Jose Manuel Viñuela-Prieto, Mayra Matesanz, Juan González Del Castillo, Ana Arribi Update in Highlights at the ASM Microbe 2018, Atlanta (USA) 10 infection related Emilia Cercenado meetings 2018 Highlights at the 28th Congress of the European Society of 16 Clinical Microbiology and Infectious Diseases (ESCMID), 2018 Sandra Nabal, Saray Mormeneo, Juan M. García-Lechuz Some highlights of the content of the San Francisco ID-Week, 22 in the area of bacterial infection Emilio Bouza Highlights from 22nd International AIDS Conference 24 María José Núñez-Orantos, Noemí Cabello Clotet, Jorge Vergas García, María Jesús Téllez Molina, Vicente Estrada Pérez Update in Current status of ESKAPE microorganisms in Spain: Epidemiology and 27 resistance phenotypes nosocomial Javier Sánchez-López, Rafael Cantón infection Antibiotic selection in the treatment of acute invasive infections 32 by Pseudomonas aeruginosa Celia Cardozo, Verónica Rico, Daiana Agüero, Alex Soriano The pharmacodynamic bases of the prescription of antimicrobials 35 José Ramón Azanza Perea Practical approach to the management of catheter-related 38 bloodstream infection Mª Luisa Cantón-Bulnes, José Garnacho-Montero Stewardship in sepsis 42 Jose L. del Pozo Doctor, my patient has CDI and should continue to receive antibiotics. 47 The (unresolved) risk of recurrent CDI Iván Castro, Mariona Tasias, Eva Calabuig, Miguel Salavert Update on the Update on the management of febrile neutropenia in hematologic patients 55 Francesc Escrihuela-Vidal. Júlia Laporte, Adaia Albasanz-Puig, Carlota Gudiol infection of the immunocompromised Prophylaxis of mould infections 59 Estela Moreno-García, Mariana Chumbita, Pedro Puerta-Alcalde, Celia Cardozo, Carolina Garcia- patient Vidal Contents REVISTA ESPAÑOLA DE uimioterapia Volume 32 Supplement number 2 Q September 2019 Update on the Assessment of latent infections in patients receiving 63 biological therapies infection of the Mario Fernández-Ruiz immunocompromised patient Infection in the process of organ donation 69 Oscar Len Abad Evaluation 73 questionnaire ©The Author 2019. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/). Introduction Francisco Javier Candel1 Carla Margarita Rico1 Update in Infectious Diseases 2019 Irene Díaz de la Torre1 Berta Laguna1 Jorge Martínez-Jordán1 Sara Medrano1 Mauricio César Escobar- 1 Porcel 1 2 Clinical Microbiology and Infectious Diseases Department. Hospital Clínico San Carlos. IdISSC and IML Institutes. Angel López-Delgado 2Clinical Analysis Department. Hospital Clínico San Carlos. IML Institute. Laura López-González1 3Internal Medicine Department. Hospital Clínico San Carlos. Jose Manuel Viñuela-Prieto1 4Emergency Department. Hospital Clínico San Carlos. IdISSC Institute. Mayra Matesanz3 Juan González del Castillo4 Ana Arribi1 ABSTRACT Current supplement of the magazine includes summa- ries of the lectures given in the presential course. It also in- The IX Updating Course of Antimicrobials and Infectious cludes the questionnaire with the evaluations made by the Diseases included a review of the main issues in clinical mi- students and a sheet of correct answers to be able to contrast crobiology, epidemiology and clinical aspects for a current the results. Revisions have been grouped under 3 headings to approach of infectious pathology. The present introduction guarantee a greater educational character. First of them was summarizes about the most important meetings related to an update in infection related meetings during 2018, and we infectious diseases during 2018 (ECCMID, IAS, ASM and ID have selected the European Congress of Clinical Microbiology Week). In addition, the course provides a practical information and Infectious Diseases or ECCMID, the American Society of to focus on nosocomial infection models, with immunosup- Microbiology Microbe or ASM Microbe 2018, the International pressed patients or complex multidrug-resistant pathogens. AIDS Society meeting or IAS 2018 and the Infectious Diseases The closing lecture of this year reviewed the infection during Week or ID Week 2018. For the second section, a practice ap- proach of epidemiology and clinical management of nosoco- donation
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