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Physiology News PHYSIOLOGY NEWS winter 2009 I number 77 Infant epilepsy in a mouse model A week in the life of ... a neuroscientist comedian How words and rituals change brain circuitry PowerLab : buy or rent Easy to use, easy to acquire PowerLab® Teaching Systems with LabTutor® and LabChart® soft ware have set the benchmarks in quality, ease-of-use, safety and fl exibility for over 20 years. Now, we’re proud to introduce another industry fi rst...the option to either buy or rent this powerful technology! Th e choice of purchase or rental options makes it even easier to get the world’s leading data acquisition system for Buy or Rent life science education. Our new Smart Rent Option off ers brand-new systems, low entry cost and free experiment soft ware upgrades. Talk to us to fi nd out more. Intuitive PowerLab Teaching Systems include experiments for human physiology, exercise physiology, pharmacology, Flexible Tool neurophysiology, psychophysiology, biology and more. Th e fl exibility of PowerLab systems adds to their cost- eff ectiveness – for purchasers and renters. Choose from over 100 experiments and 400 exercises More for introductory through to advanced levels. You can select the software for your courses and use authoring tools to modify/create experiments. Choose from over Experiments 20 Teaching Systems or let us create a customised solution. Contact us for an obligation-free demonstration. Tel: 01865 891 623 Email: [email protected] Web: www.adinstruments.com/buy_rent EQUIPMENT CERTIFIED FOR HUMAN CONNECTION UK • GERMANY • USA • BRAZIL • CHILE • INDIA • JAPAN • CHINA • MALAYSIA • NEW ZEALAND • AUSTRALIA CELEBRATING OVER 20 YEARS OF INNOVATIONS ADI_InstStudent_UK_PhysioNews.indd 1 15/5/09 2:32:20 PM PHYSIOLOGY NEWS Editorial 3 The Society’s dog. ‘Rudolf Magnus Meetings gave me to Charles Sherrington, who The hypothalamic paraventricular nucleus in health and disease gave me to Henry Dale, who gave Julian Paton 4 me to The Physiological Society in Epithelial form, function and environment Andi Werner, October 1942’ Mike Gray 6 Festschrift symposium in honour of Edward J Johns Published quarterly by The Physiological Society John Mackrill 7 Contributions and queries Lighthouses and lobsters in Woods Hole Rachel Ashworth 8 Senior Production Editor Translating ‘omics’ into functional and clinical applications Jill Berriman Thelma Lovick 9 Editorial Administrator Festschrift in honour of John Russell Mike Ludwig 10 Ed Sexton Physiology 2009 – Dublin James FX Jones 11 The Physiological Society Publications Offi ce PO Box 502, Cambridge CB1 0AL, UK IUPS Kyoto 2009 Douglas Bovell, Fiona Randall 12 Tel: +44 (0)1223 400180 A week in the life of... Fax: +44 (0)1223 246858 ... a neuroscientist comedian Dean Burnett 14 Email: [email protected] Interview Website: www.physoc.org Understanding ion channels and their role in brain disorders Magazine Editorial Board Bill Catterall, Angus Brown 15 Letter from Japan 3 Editor Embracing a new culture Fiona Randall 19 Austin Elliott Features University of Manchester, Manchester, UK Excitation-dependent Ca2+ infl ux in vertebrate skeletal muscle Members is in, again Bradley Launikonis, Oliver Friedrich, Angus Brown George Stephenson 20 University of Nottingham, Nottingham, UK Regulation of extracellular pH by purinergic signalling Patricia de Winter Jonathan Kaunitz, Yasutada Akiba 22 University College London, London, UK Fractals in human physiology revisited Can Ozan Tan, Sarah Hall Andrew Taylor 25 Cardiff University, Cardiff, UK Sheet-like tendons are stiffened by bulging muscles Munir Hussain Emanuel Azizi, Thomas Roberts 28 University of Bradford, Bradford, UK The placebo response: how words and rituals change brain John Lee circuitry Fabrizio Benedetti, Michele Lanotte, Leonardo Rotherham General Hospital, Rotherham, UK Lopiano 30 Thelma Lovick Neuromuscular interaction during human walking: how do University of Birmingham, Birmingham, UK changes in muscle–tendon mechanics affect the motor control of walking? Neil Cronin 32 Foreign Correspondents Techniques John Hanrahan Multiple tests correction, false discovery rate and q value McGill University, Montreal, Canada Fumiaki Katagiri 35 John Morley Reports University of Western Sydney, NSW, Australia The Hodgkin–Huxley–Katz Prize Lecture delivered by Eric Fiona Randall Kandel Otto Hutter 39 Okinawa Institute of Science and Technology, Okinawa, WHO does not recommend the use of homeopathy for HIV, Japan malaria, TB, infl uenza and infant diarrhoea Julia Wilson 40 © 2009 The Physiological Society From the archives Austin Elliott 41 ISSN 1476-7996 (Print) Society of Biology 42 ISSN 2041-6512 (Online) Unbelievable! 43 The Physiological Society is registered in England as a Musings from the Chief Executive’s Desk Mike Collis 44 company limited by guarantee: No 323575. The Society’s journals Registered offi ce: PO Box 11319, London WC1X The Journal of Physiology 45 8WQ. Membership Registered Charity: No 211585. Snakes and ladders David Green 47 Printed by The Lavenham Press Ltd XIth Little Brain Big Brain Meeting Christopher Keating 48 Noticeboard 48 Education Coming in from the cold: physiology at the Cheltenham Festival Sarah Hall 49 Young Physiologists’ Symposium, Dublin Karen Griffi n 50 The British Science Festival, Guildford 2009 Freya Hopper 50 New Council and Affi liate Members of Council 51 Obituaries Ron Cook Ann Silver, Peter Stanfi eld, Alan Cattell 54 Cover image: an ‘H-fractal’. From Tan & Jeff Potts Peter Raven, Jere Mitchell, Artin Shoukas, Julian Paton 55 Advancing the science of life Taylor, pp. 25 PHYSIOLOGY NEWS Action points Guidelines for contributors In this issue Grants These guidelines are intended to assist Welcome to the final Physiology News The Society offers funding authors in writing their contributions and to reduce the subsequent editing of 2009. through the following grant process. The Editorial Board of schemes: Travel Grants, Non- Physiology News tries to ensure that all This stage of the year usually Society Symposia Grants, articles are written in a journalistic style brings a round-up of the summer’s Outreach Grants, International so that they will have an immediate conferences, and this year is no Teaching and Research Grants interest value for a wide readership and exception – I think I counted nine and the Vacation Studentship and will be readable and comprehensible to reports – or it might have been ten non-experts. Scientific articles should or eleven! – including reports from Departmental Seminar Schemes. give a good overview of a field rather For full information, please visit: than focus entirely on the authors’ own three continents. www.physoc.org/grants research. An unusual ‘Week in the Life’ this Format of articles issue gives us – the neuroscientist- Membership applications The main message or question posed Applications for membership comedian. Neuroscientist-writers should be introduced in the first are perhaps not all that rare, but to The Physiological Society are paragraph. The background for the comedians are rather scarcer. considered on a rolling basis, topic should then be established, Though, as writer Dean Burnett and a decision is normally made leading up to the final conclusion. points out, there are ex-scientist, within 15 working days. For full Length of articles or ex-doctor, comedians – such as information, please visit: This will be determined by the subject the Irish Dara O’Briain (BSc Maths & www.physoc.org/membership matter and agreed with the Senior Production Editor. Theoretical Physics, UC Dublin) or British comic Harry Hill (MBBS St Submission of articles Is your membership information Georges Hospital Medical School). correct? Authors should submit articles as a Trying to juggle the comedy and the Word document attached to an email. Please check and update your science is even more of a challenge, details at www.physoc.org, under Illustrations should be sent as separate attachments (see below) and not as Dean describes in his diary (p. 14). ‘My Physoc Profile’. embedded in the text. Scientific content is served with six Illustrations and authors’ photographs News and Views articles, as well as Authors are encouraged to submit the latest in what is already proving Physiology News diagrams, drawings, photographs or to be a very popular Techniques Deadlines other artwork with their articles and a photograph of the author(s) should series. Something a bit unusual Letters and articles and all other accompany submissions. llustrations can be found on p. 30, where contributions for inclusion in the and photographs may be colour or black Fabrizio Benedetti et al. discuss the Spring 2010 issue, No. 78, and white, and preferably TIFF, JPEG, physiology, and brain circuitry, of the PNG, PDF or AI files with a minimum placebo response. Placebo therapies should reach the Publications resolution of 300 dpi. Office ([email protected]) also get a look-over in a somewhat References by 14 January 2010. Short news different context on p. 40. Authors are requested to keep the items and letters are encouraged, number of references to a minimum – This issue we are saying hello to a and can usually be included as late preferably no more than two or three. slate of new journal Editors, new copy if space permits. Please cite all references in the style of Society Council Members, and The Journal of Physiology (see new office staff, all of whom tell us Suggestions for articles Information and Guidance for Authors at Suggestions for future articles are http://jp.physoc.org). something about themselves (pp. 45 welcome. Please contact either and 51). The Physiological Society permits the the Editorial Administrator or a single copying of individual articles for Finally, as well as saying hello, the member of the Editorial Board private study or research. For permission issue also features some goodbyes. of Physiology News (see contents to copy or reproduce for any other Goodbyes can be celebrations of page for details). purpose contact [email protected]. the careers of colleagues who are Opinions expressed in articles and letters reaching well-deserved retirements Physiology News online submitted by, or commissioned from, (pp.
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