Lysosomal Membrane Permeabilization and Cathepsin
Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes Christoph Borner, Carolin Oberle, Thomas Reinheckel, Marlene Tacke, Jan Buellesbach, Paul G Ekert, Jisen Huai, Mark Rassner To cite this version: Christoph Borner, Carolin Oberle, Thomas Reinheckel, Marlene Tacke, Jan Buellesbach, et al.. Lyso- somal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes. Cell Death and Differentiation, Nature Publishing Group, 2010, n/a (n/a), pp.n/a-n/a. 10.1038/cdd.2009.214. hal-00504935 HAL Id: hal-00504935 https://hal.archives-ouvertes.fr/hal-00504935 Submitted on 22 Jul 2010 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes Carolin Oberle1,6, Jisen Huai1, Thomas Reinheckel1, Marlene Tacke1, Mark Rassner1,4, Paul G. Ekert2, Jan Buellesbach3,4, and Christoph 1,3,5§ Borner 1Institute of Molecular Medicine and Cell Research, Center for Biochemistry and Molecular Cell Research, Albert Ludwigs University Freiburg, Stefan Meier Str. 17, D-79104 Freiburg, Germany 2Children’ Cancer Centre, Murdoch Children’s Research Institute, Royal Children’s Hospital, Flemington Rd., Parkville, Victoria, 3052 Australia 3Graduate School of Biology and Medicine (SGBM), Albert Ludwigs University Freiburg, Albertstr.
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