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Our Creed is what We Believe. It May Seem Like We’ve Been Fighting This We see leading researchers, from all over the Fight Forever. But We Haven’t. world, leave their homes to come here. Because this is where they believe the fight will be There was a time, not long ago, when cancer finished. In our lifetime. was a death sentence. And the treatment was dreaded almost as much as the disease. Yes, we are still losing people to cancer. But We’ve seen that change in our lifetime, at more and more, we are controlling the cancer, The Princess Margaret. instead of the cancer controlling us. We now know that every cancer is as individual as the We’ve seen the entire process of cancer patient. So we’re developing personalized care care forever altered. We’ve seen radical that delivers the right treatment to the right mastectomies become lumpectomies. We’ve patient at the right time. We are pioneering seen the precision of image guided therapies new, innovative treatment options, like using spare more healthy tissue. We’ve seen a patient’s own immune system to fight cancer. undreamed-of advances at the cellular level and This is the future of cancer medicine, and we revolutionary work in healing beyond the body. are on the forefront of that progress, today. All in our lifetime. It may seem like we’ll be fighting this fight All at The Princess Margaret. forever. But we won’t. Because we’re closing in. We have the momentum. We have the talent. We see the things we do give hope to millions, And we have the passion. This is the front line. one person at a time. We’ve transformed We are Canada’s cancer warriors. But we can’t a provincial cancer hospital into one of the do it alone. world’s top five cancer research centres. As a proud partner of the University Health The world needs to hear The Princess Margaret Network, we’ve grown our people into message. So share it at every opportunity with the thousands - each of them dedicated to anyone who will listen. finding more effective ways to care for cancer It’s a simple message, really. But it’s a message patients. We share our research findings of incredible power: we are conquering cancer and clinical expertise globally. Through our at Canada’s cancer research centre, The Princess critical teaching role, we are training the next Margaret. In our lifetime. generation of cancer experts and impacting patient care at The Princess Margaret, across Canada and around the globe. The world needs to hear The Princess Margaret message. So share it at every opportunity with anyone who will listen. *For more information on The Princess Margaret’s global impact, go to www.thepmcf.ca The Princess Margaret Cancer Foundation 1 Marking 20 years on University Avenue, and visualizing the 20 years ahead November 2015 marked the 20th anniversary of in patient care in the future are major Princess Margaret Cancer Centre’s move from its priorities for our healthcare system. original location on Sherbourne Street to its current As part of University Health Network, location in the heart of Toronto’s Medical Discovery The Princess Margaret benefits from District on University Avenue. It was an opportunity to technology development that is pay tribute to the progress made in the past 20 years taking place across the organization. and open a dialogue about our aspirations and ideas New ‘apps’ that help patients manage on how the care of cancer patients will change in the their disease are being readied for next 20 years. prime time. A number of esteemed speakers shared their As for The Princess Margaret’s predictions about the future of cancer research and specific vision to Conquer Cancer healthcare systems in 2035, including Dr. Peter Pisters, in Our Lifetime, we are optimistic. President and CEO of University Health Network, who For example, we are leading in the described his vision: application of new tools that allow us to map the genome of each patient’s tumor and understand the specific “We will facilitate a process where driver mutations that are fueling there will be much more real-time it. The days of treating all patients with lung cancer or with colon cancer in the same way access to clinical decision support, are behind us. We are now in the age of Personalized Cancer Medicine. to data that’s required to manage Virtually every week, we read something in the diseases in real time, and where news about the potential of our immune system to recognize and eradicate cancer. We saw this patients will become partners in opportunity early and have built on historical strength their care in a much different way developed over the past 20 years through additional recruitment and investment. As we translate our than they are engaged now.” research discoveries from the laboratory to the clinic, we are playing an important role on the world stage in developing and evaluating new approaches to utilize Harnessing technology to connect patients and their our own immune system to seek out and target cancer. healthcare team in efficient ways and managing the We foresee the day when cancer will be treated as a overwhelming amount of data that will be produced chronic disease like diabetes is treated today. 2 2016 Report to Our Donors A message from Dr. Bradly Wouters and Dr. Mary Gospodarowicz As part of celebrating the 20-year milestone, we asked our staff and friends to select just one word to describe The Princess Margaret. The word map shown illustrates what came to mind for people. Thank you for supporting our research and innovation as we work to conquer cancer in our lifetime, Dr. Bradly Wouters Dr. Mary Gospodarowicz Research Director Medical Director Princess Margaret Cancer Centre Princess Margaret Cancer Centre The Princess Margaret Cancer Foundation 3 The home stretch of our BILLION DOLLAR CHALLENGE In April 2012, The Princess Margaret Cancer Foundation This is the next chapter in an event that will be 15 years embarked on the largest single fundraising campaign strong next year, and is continuously evolving with in the history of Canadian healthcare. And this year, feedback and great ideas from our dedicated supporters. we completed the fourth year of the BILLION DOLLAR We are delighted that Rexall has signed on as the title CHALLENGE—our five-year initiative to secure $1 billion sponsor for the 2016 event . to lead the way in Personalized Cancer Medicine at The Enbridge Ride to Conquer Cancer had another Princess Margaret Cancer Centre, one of the top 5 cancer incredible year, raising over $19.3 million with 4,853 research centres in the world. riders. We have shared this great event brand to benefit By the time you read this report, we will be very close three other Canadian cancer organizations—B.C. Cancer to reaching our goal. We have raised $870 million, with Foundation, Alberta Cancer Foundation and Montreal’s $443 million coming from philanthropy and $427 million Jewish General Hospital Foundation. In total, over eight from grants secured by our internationally-respected years, the Ride has raised $315 million for cancer research research team. and care across the country. In fiscal 2016, we achieved a new record in our net For the second consecutive year, our Princess Margaret fundraising with a total of $104 million. This includes lotteries raised an all-time record of $24.8 million in $15.5 million raised for our $50 million Research net income through continuous innovation in ticket Campaign which launched in 2015. (See page 18 for more purchase options, prizing and use of social media to information on this campaign). reach new buyers. The continued generosity of donors such as Emmanuelle Thanks to the cancer research enabled through these Gattuso, Allan Slaight and the Slaight family has enabled programs and your generosity, the landscape in cancer us to amplify the expertise of our research team in diagnosis and treatment is changing rapidly. The key areas including epigenetics, bioinformatics, drug Tumor Immunotherapy Program led by Drs. Pamela development, and immunotherapy. Ohashi and Lillian Siu is an excellent example of how This year, we celebrated the formation of the Till & The Princess Margaret is leading the way in testing McCulloch Society, which recognizes our supporters promising new approaches to cancer treatment by who have fuelled work at The Princess Margaret through activating our immune system. The leaders of this cumulative giving that has exceeded $1 million. Several program are highly regarded around the world, and events have already been held for Society members that they are working in collaboration with the top U.S. connect them with clinicians and researchers whose work cancer centres. This is a key area of investment for our is benefitting from their support. Research Campaign. OneWalk to Conquer Cancer made its debut in This report provides further details on our September 2015 with 4,523 participants raising over immunotherapy program and other examples of how $7.7 million. The Princess Margaret is outsmarting cancer thanks to your support. 4 2016 Report to Our Donors A message from the Chair of the Foundation Board and the President and CEO Tom Ehrlich Paul Alofs Chair, Board of Directors President & CEO The Princess Margaret Cancer Foundation 5 Canada’s most comprehensive immunotherapy program It’s not a new idea that our immune system can kill cancer At The Princess Margaret, several drugs are being tested cells. From 60 Minutes to CNN, the popular press is abuzz to take advantage of these ‘gas pedals’ and boost the with stories.

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