Identification of Genomic Regions Associated with Phenotypic Variation Between Dog Breeds Using Selection Mapping
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Dog Breeds of the World
Dog Breeds of the World Get your own copy of this book Visit: www.plexidors.com Call: 800-283-8045 Written by: Maria Sadowski PlexiDor Performance Pet Doors 4523 30th St West #E502 Bradenton, FL 34207 http://www.plexidors.com Dog Breeds of the World is written by Maria Sadowski Copyright @2015 by PlexiDor Performance Pet Doors Published in the United States of America August 2015 All rights reserved. No portion of this book may be reproduced or transmitted in any form or by any electronic or mechanical means, including photocopying, recording, or by any information retrieval and storage system without permission from PlexiDor Performance Pet Doors. Stock images from canstockphoto.com, istockphoto.com, and dreamstime.com Dog Breeds of the World It isn’t possible to put an exact number on the Does breed matter? dog breeds of the world, because many varieties can be recognized by one breed registration The breed matters to a certain extent. Many group but not by another. The World Canine people believe that dog breeds mostly have an Organization is the largest internationally impact on the outside of the dog, but through the accepted registry of dog breeds, and they have ages breeds have been created based on wanted more than 340 breeds. behaviors such as hunting and herding. Dog breeds aren’t scientifical classifications; they’re It is important to pick a dog that fits the family’s groupings based on similar characteristics of lifestyle. If you want a dog with a special look but appearance and behavior. Some breeds have the breed characterics seem difficult to handle you existed for thousands of years, and others are fairly might want to look for a mixed breed dog. -
Ranked by Temperament
Comparing Temperament and Breed temperament was determined using the American 114 DOG BREEDS Popularity in Dog Breeds in Temperament Test Society's (ATTS) cumulative test RANKED BY TEMPERAMENT the United States result data since 1977, and breed popularity was determined using the American Kennel Club's (AKC) 2018 ranking based on total breed registrations. Number Tested <201 201-400 401-600 601-800 801-1000 >1000 American Kennel Club 50% 60% 70% 80% 90% 1. Labrador 100% Popularity Passed 2. German Retriever Passed Shepherd 3. Mixed Breed 7. Beagle Dog 4. Golden Retriever More Popular 8. Poodle 11. Rottweiler 5. French Bulldog 6. Bulldog (Miniature)10. Poodle (Toy) 15. Dachshund (all varieties) 9. Poodle (Standard) 17. Siberian 16. Pembroke 13. Yorkshire 14. Boxer 18. Australian Terrier Husky Welsh Corgi Shepherd More Popular 12. German Shorthaired 21. Cavalier King Pointer Charles Spaniel 29. English 28. Brittany 20. Doberman Spaniel 22. Miniature Pinscher 19. Great Dane Springer Spaniel 24. Boston 27. Shetland Schnauzer Terrier Sheepdog NOTE: We excluded breeds that had fewer 25. Bernese 30. Pug Mountain Dog 33. English than 30 individual dogs tested. 23. Shih Tzu 38. Weimaraner 32. Cocker 35. Cane Corso Cocker Spaniel Spaniel 26. Pomeranian 31. Mastiff 36. Chihuahua 34. Vizsla 40. Basset Hound 37. Border Collie 41. Newfoundland 46. Bichon 39. Collie Frise 42. Rhodesian 44. Belgian 47. Akita Ridgeback Malinois 49. Bloodhound 48. Saint Bernard 45. Chesapeake 51. Bullmastiff Bay Retriever 43. West Highland White Terrier 50. Portuguese 54. Australian Water Dog Cattle Dog 56. Scottish 53. Papillon Terrier 52. Soft Coated 55. Dalmatian Wheaten Terrier 57. -
Rethinking Dog Domestication by Integrating Genetics, Archeology, and Biogeography
Rethinking dog domestication by integrating genetics, archeology, and biogeography Greger Larsona,1, Elinor K. Karlssonb,c, Angela Perria, Matthew T. Webster d,SimonY.W.Hoe, Joris Petersf, Peter W. Stahl g, Philip J. Piperh,i, Frode Lingaasj, Merete Fredholmk, Kenine E. Comstockl, Jaime F. Modianom,n, Claude Schellingo, Alexander I. Agoulnikp, Peter A. Leegwaterq, Keith Dobneyr, Jean-Denis Vignes, Carles Vilàt, Leif Anderssond,u, and Kerstin Lindblad-Tohb,d aDurham Evolution and Ancient DNA, Department of Archaeology, University of Durham, Durham DH1 3LE, United Kingdom; bBroad Institute of MIT and Harvard, Cambridge MA 02142; cFaculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge MA 02138; dScience for Life Laboratory Uppsala, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; eSchool of Biological Sciences, University of Sydney, Sydney NSW 2006, Australia; fVeterinary Sciences Department, Institute of Palaeoanatomy, Domestication Research and the History of Veterinary Medicine, Ludwig-Maximilian University, 80539 Munich, Germany; gDepartment of Anthropology, University of Victoria, Victoria, BC, Canada V8W 2Y2; hSchool of Archaeology and Anthropology, Australian National University, Canberra, Australian Capital Territory 200, Australia; iArchaeological Studies Program, University of the Philippines, Diliman, 1101, Quezon City, Philippines; jDepartment of Basic Sciences and Aquatic Medicine, Division of Genetics, Norwegian School of Veterinary Science, -
Cytogenetic Analysis of a Pseudoangiomatous Pleomorphic/Spindle Cell Lipoma
ANTICANCER RESEARCH 37 : 2219-2223 (2017) doi:10.21873/anticanres.11557 Cytogenetic Analysis of a Pseudoangiomatous Pleomorphic/Spindle Cell Lipoma IOANNIS PANAGOPOULOS 1, LUDMILA GORUNOVA 1, INGVILD LOBMAIER 2, HEGE KILEN ANDERSEN 1, BODIL BJERKEHAGEN 2 and SVERRE HEIM 1,3 1Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; 2Department of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; 3Faculty of Medicine, University of Oslo, Oslo, Norway Abstract. Background: Pseudoangiomatous pleomorphic/ appearance’ (1). To date, only 20 patients have been described spindle cell lipoma is a rare subtype of pleomorphic/spindle in the literature with this diagnosis, 15 of whom were males cell lipoma. Only approximately 20 such tumors have been (1-10). The pseudoangiomatous pleomorphic/spindle cell described. Genetic information on pseudoangiomatous lipomas were mostly found in the neck (seven patients) and pleomorphic/spindle cell lipoma is restricted to a single case shoulders (four patients), but have also been seen in the in which deletion of the forkhead box O1 (FOXO1) gene was cheek, chest, chin, elbow, finger, subscapular region, and found, using fluorescence in situ hybridization (FISH). thumb. Genetic information on pseudoangiomatous Materials and Methods: G-banding and FISH analyses were pleomorphic/ spindle cell lipoma is restricted to one case only performed on a pseudoangiomatous pleomorphic/spindle cell (8) in which fluorescence in situ hybridization (FISH) with a lipoma. Results: G-banding of tumor cells showed complex probe for the forkhead box O1 ( FOXO1 ) gene, which maps karyotypic changes including loss of chromosome 13. FISH to chromosome sub-band 13q14.11, showed a signal pattern analysis revealed that the deleted region contained the RB1 indicating monoallelic loss of the gene in 57% of the gene (13q14.2) and the part of chromosome arm 13q (q14.2- examined cells. -
2017 Horrible Hundred Report
The Horrible Hundred 2017 A sampling of problem puppy mills and puppy dealers in the United States May 2017 For the fifth straight year, The Humane Society of the United States is reporting on problem puppy mills, including some dealers (re-sellers) and transporters. The Horrible Hundred 2017 report is a list of known, problematic puppy breeding and/or puppy brokering facilities. It is not a list of all puppy mills, nor is it a list of the worst puppy mills in the country. The HSUS provides this update annually, not as a comprehensive inventory, but as an effort to inform the public about common, recurring problems at puppy mills. The information in this report demonstrates the scope of the puppy mill problem in America today, with specific examples of the types of violations that researchers have found at such facilities, for the purposes of warning consumers about the inhumane conditions that so many puppy buyers inadvertently support. The year 2017 has been a difficult one for puppy mill watchdogs. Efforts to get updated information from the United States Department of Agriculture (USDA) on federally-inspected puppy mills were severely crippled due to the USDA’s removal on Feb. 3, 2017 of all animal welfare inspection reports and most enforcement records from the USDA website. As of April 20, 2017, the USDA had restored some Puppies at the facility of Alvin Nolt in Thorpe, Wisconsin, were found on unsafe wire flooring, a repeat violation at the facility. Wire flooring animal welfare records on research facilities and is especially dangerous for puppies because their legs can become other types of dealers, but almost no records on entrapped in the gaps, leaving them unable to reach food, water or pet breeding operations were restored. -
ECM Alterations in Fndc3a (Fibronectin Domain Containing
www.nature.com/scientificreports OPEN ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) defcient zebrafsh Received: 22 April 2019 Accepted: 5 September 2019 cause temporal fn development Published: xx xx xxxx and regeneration defects Daniel Liedtke 1, Melanie Orth1, Michelle Meissler1, Sinje Geuer2,3, Sabine Knaup1, Isabell Köblitz1,4 & Eva Klopocki 1 Fin development and regeneration are complex biological processes that are highly relevant in teleost fsh. They share genetic factors, signaling pathways and cellular properties to coordinate formation of regularly shaped extremities. Especially correct tissue structure defned by extracellular matrix (ECM) formation is essential. Gene expression and protein localization studies demonstrated expression of fndc3a (fbronectin domain containing protein 3a) in both developing and regenerating caudal fns of zebrafsh (Danio rerio). We established a hypomorphic fndc3a mutant line (fndc3awue1/wue1) via CRISPR/ Cas9, exhibiting phenotypic malformations and changed gene expression patterns during early stages of median fn fold development. These developmental efects are mostly temporary, but result in a fraction of adults with permanent tail fn deformations. In addition, caudal fn regeneration in adult fndc3awue1/wue1 mutants is hampered by interference with actinotrichia formation and epidermal cell organization. Investigation of the ECM implies that loss of epidermal tissue structure is a common cause for both of the observed defects. Our results thereby provide a molecular link between these developmental processes and foreshadow Fndc3a as a novel temporal regulator of epidermal cell properties during extremity development and regeneration in zebrafsh. A wide number of conserved genetic and structural features have been identifed regulating fn development in ray fnned fsh species, like zebrafsh (Danio rerio), and imply shared mechanisms throughout evolution1. -
Border Collie
SCRAPS Breed Profile SHAR-PEI Stats Country of Origin: China Group: Non-Sporting Use today: Family companion, guarding, and hunting. Life Span: Up to 10 years Color: Coat colors include all solid colors and sables. Coat: There are three coat varieties: horse-coat; rough, extremely prickly & off-standing, brush-coat; has longer hair and a smoother feel and bear-coat; has an undercoat and a topcoat exceeding 1 inch.. Grooming: The Shar-Pei should be brushed regularly. Their coat is never trimmed. This breed does not have an undercoat. The "bush" coat sheds a little year round, but the "horse" coat tends to shed only during molting periods. Molting may leave the dog looking unkempt. Bathing about once a week and brushing the coat daily during this period will remove the old dead hair and allow the new coat to grow in. Some owners are allergic to the harsh coat. Height: 18 – 20 inches Weight: 40 – 55 pounds Profile In Brief: An intelligent and often stubborn breed, coat on either variety can be up to one inch in Shar Pei ownership needs careful consideration. length. Coat colors include all solid colors and They are bright and learn quickly, but early sables. There is also a lowered, spotted, and a training and socialization are important, as is particular colored Shar-Pei coat, which is a daily exercise. Shar-Pei are clean dogs that disqualifying fault in the show ring according to require little more grooming than an occasional AKC standard. The small ears fall forward and bath, regular ear cleaning and toe nail clipping. -
Alphabetic Breedslist 12/08/201 2018 SHOW DOG
Alphabetic Breedslist 12/08/2018 - WORLD DOG SHOW 2018 Count Breed Cat.Nrs. Ring 35 II Affenpinscher 9721-9755 11 128 V Akita 13888-14015 44 Bis 105 V Alaskan Malamute 12845-12949 42 Bis 82 V American Akita 14016-14097 43 b 9 II Anatolian Shepherd Dog 11882-11890 22 b 25 II Appenzell Cattle Dog 12421-12445 26 2 II Austrian Pinscher 9756-9757 32 Bis 95 V Basenji 14508-14602 47 83 II Bernese Mountain Dog - Males 12446-12528 3 91 II Bernese Mountain Dog - Females 12529-12619 4 80 IX Bichon Frise 14894-14973 63 b 42 IX Bolognese 14974-15015 65 8 II Bosnian-Herzegovinian Croation Shepherd Dog 11918-11925 10 153 IX Boston Terrier 17467-17619 54 111 II Boxer 10677-10787 18 24 II Broholmer 10653-10676 51 a 107 II Bulldog - Males 11318-11424 17 97 II Bulldog - Females 11425-11521 20 102 II Bullmastiff 11522-11623 6 4 V Canaan Dog 14294-14297 51 a 7 V CANADIAN ESKIMO DOG 12707-12713 42 3 V Canarian Warren Hound 14603-14605 42 33 II Caucasian Shepherd Dog 12312-12344 8 110 IX Cavalier King Charles Spaniel 16545-16654 74 9 II Central Asia Shepherd Dog 12345-12353 22 b 70 IX Chihuahua long-Haired - Females 16475-16544 56 91 IX Chihuahua long-Haired - Males 16384-16474 55 68 IX Chihuahua Smooth-haired - Males 16240-16307 53 76 IX Chihuahua Smooth-haired - Females 16308-16383 52 78 IX Chinese Crested Dog - Females 15783-15860 50 77 IX Chinese Crested Dog - Males 15706-15782 51 b 65 V Chow Chow 13767-13831 38 7 II Cinmarrón Uruguaya 11891-11897 35 25 V Cirneco dell'Etna 14641-14665 36 a 115 IX Continental Toy Spaniel, Papillon 16799-16913 67 16 IX Continental -
ID AKI Vs Control Fold Change P Value Symbol Entrez Gene Name *In
ID AKI vs control P value Symbol Entrez Gene Name *In case of multiple probesets per gene, one with the highest fold change was selected. Fold Change 208083_s_at 7.88 0.000932 ITGB6 integrin, beta 6 202376_at 6.12 0.000518 SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1553575_at 5.62 0.0033 MT-ND6 NADH dehydrogenase, subunit 6 (complex I) 212768_s_at 5.50 0.000896 OLFM4 olfactomedin 4 206157_at 5.26 0.00177 PTX3 pentraxin 3, long 212531_at 4.26 0.00405 LCN2 lipocalin 2 215646_s_at 4.13 0.00408 VCAN versican 202018_s_at 4.12 0.0318 LTF lactotransferrin 203021_at 4.05 0.0129 SLPI secretory leukocyte peptidase inhibitor 222486_s_at 4.03 0.000329 ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1552439_s_at 3.82 0.000714 MEGF11 multiple EGF-like-domains 11 210602_s_at 3.74 0.000408 CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 229947_at 3.62 0.00843 PI15 peptidase inhibitor 15 204006_s_at 3.39 0.00241 FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 202238_s_at 3.29 0.00492 NNMT nicotinamide N-methyltransferase 202917_s_at 3.20 0.00369 S100A8 S100 calcium binding protein A8 215223_s_at 3.17 0.000516 SOD2 superoxide dismutase 2, mitochondrial 204627_s_at 3.04 0.00619 ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 223217_s_at 2.99 0.00397 NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 231067_s_at 2.97 0.00681 AKAP12 A kinase (PRKA) anchor protein 12 224917_at 2.94 0.00256 VMP1/ mir-21likely ortholog -
Non-Sporting Dogs
GROUP VI NON-SPORTING DOGS n American Eskimo Dog (Miniature & Standard) n Bichon Frise n Boston Terrier n Bulldog n Chinese Shar-Pei n Chow Chow n Dalmatian n French Bulldog n German Pinscher n Japanese Spitz n Keeshond n Lhasa Apso n Lowchen n Poodle (Miniature & Standard) n Schipperke n Shiba Inu n Shih Tzu n Tibetan Spaniel n Tibetan Terrier n Xoloitzcuintli (Miniature & Standard) Listed Breeds n Akita (Japanese) 306-06-05 Canadian Kennel Club Official Breed Standards GROUP VI NON-SPORTING DOGS VI-1 American Eskimo Dog (Miniature & Standard) General Appearance The American Eskimo Dog, a loving companion dog, presents a picture of strength and agility, alertness and beauty. It is a small to medium- size Nordic type dog, always white, or white with biscuit cream. The American Eskimo Dog is compactly built and well balanced, with good substance, and an alert smooth gait. The face is Nordic type with erect triangular shaped ears and distinctive black points (lips. nose. and eye rims). The white double coat consists of a short, dense undercoat, with a longer guard hair growing through it forming the outer coat, which is straight with no curl or wave. The coat is thicker and longer around the neck and chest forming a lion-like ruff, which is more noticeable on dogs than on bitches. The rump and hind legs down to the hocks are also covered with thicker, longer hair forming the characteristic breeches. The richly plumed tail is carried loosely on the back. Temperament The American Eskimo Dog is intelligent, alert, and friendly, although slightly conservative. -
Domestic Dog Breeding Has Been Practiced for Centuries Across the a History of Dog Breeding Entire Globe
ANCESTRY GREY WOLF TAYMYR WOLF OF THE DOMESTIC DOG: Domestic dog breeding has been practiced for centuries across the A history of dog breeding entire globe. Ancestor wolves, primarily the Grey Wolf and Taymyr Wolf, evolved, migrated, and bred into local breeds specific to areas from ancient wolves to of certain countries. Local breeds, differentiated by the process of evolution an migration with little human intervention, bred into basal present pedigrees breeds. Humans then began to focus these breeds into specified BREED Basal breed, no further breeding Relation by selective Relation by selective BREED Basal breed, additional breeding pedigrees, and over time, became the modern breeds you see Direct Relation breeding breeding through BREED Alive migration BREED Subsequent breed, no further breeding Additional Relation BREED Extinct Relation by Migration BREED Subsequent breed, additional breeding around the world today. This ancestral tree charts the structure from wolf to modern breeds showing overlapping connections between Asia Australia Africa Eurasia Europe North America Central/ South Source: www.pbs.org America evolution, wolf migration, and peoples’ migration. WOLVES & CANIDS ANCIENT BREEDS BASAL BREEDS MODERN BREEDS Predate history 3000-1000 BC 1-1900 AD 1901-PRESENT S G O D N A I L A R T S U A L KELPIE Source: sciencemag.org A C Many iterations of dingo-type dogs have been found in the aborigine cave paintings of Australia. However, many O of the uniquely Australian breeds were created by the L migration of European dogs by way of their owners. STUMPY TAIL CATTLE DOG Because of this, many Australian dogs are more closely related to European breeds than any original Australian breeds. -
Loss of PRDM1/BLIMP-1 Function Contributes to Poor Prognosis for Activated B-Cell–Like Diffuse Large B-Cell Lymphoma
HHS Public Access Author manuscript Author ManuscriptAuthor Manuscript Author Leukemia Manuscript Author . Author manuscript; Manuscript Author available in PMC 2018 March 05. Published in final edited form as: Leukemia. 2017 March ; 31(3): 625–636. doi:10.1038/leu.2016.243. Loss of PRDM1/BLIMP-1 function contributes to poor prognosis for activated B-cell–like diffuse large B-cell lymphoma Yi Xia1,2,*, Zijun Y. Xu-Monette1,*, Alexandar Tzankov3,*, Xin Li1, Ganiraju C. Manyam4, Vundavalli Murty5, Govind Bhagat5, Shanxiang Zhang1, Laura Pasqualucci5, Li Zhang4, Carlo Visco6, Karen Dybkaer7, April Chiu8, Attilio Orazi9, Youli Zu10, Kristy L. Richards11, Eric D. Hsi12, William W.L. Choi13, J. Han van Krieken14, Jooryung Huh15, Maurilio Ponzoni16, Andrés J.M. Ferreri16, Michael B. Møller17, Ben M. Parsons18, Jane N. Winter19, Miguel A. Piris20, Jason Westin21, Nathan Fowler21, Roberto N. Miranda1, Chi Young Ok1, Jianyong Li2,¶, L. Jeffrey Medeiros1, and Ken H. Young1,22,¶ 1Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 2The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China 3University Hospital, Basel, Switzerland 4Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA 5Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA 6San Bortolo Hospital, Vicenza, Italy 7Aalborg University Hospital, Aalborg, Denmark 8Memorial Sloan-Kettering Cancer Center, New York, NY, USA 9Weill Medical College of Cornell University, New York, NY, USA 10The Methodist Hospital, Houston, TX, USA 11Cornell University, Ithaca, NY, USA 12Cleveland Clinic, Cleveland, OH, USA 13University of Hong Kong Li Ka Shing Faculty of Medicine, Hong Kong, China 14Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands 15Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea 16San Raffaele H.