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Otc Research Program OTC Foundation at a Glance Outlook 2015-16 OTC RESEARCH COURSES OTC WORKSHOPS 2011-12 OTC WORKSHOPS 2013-14 BOOKS PUBLICATIONS PRESENTATIONS OTC RESEARCH PROGRAM OTC FOUNDATION AT A GLANCE OUTLOOK 2015-16 OTC RESEARCH PROGRAM 2011 - 2014 OTC RESEARCH PROGRAM 20011-14 RESEARCH PROGRAM HISTORY RESEARCH COMMITTEE MEMBERS SUPPORTING RESEARCHERS WORLDWIDE REVIEW PROCESS YOUNG INVESTIGATOR GRANTS 2011 RESEARCH GRANTS 2011-14 OTC Research Program 2011-14 RESEARCH COMMITTEE INTRODUCTION The Osteosynthesis and Trauma Care Foundation is research supported by the OTC Foundation over an educational and scientific professional organization the last four years. Many of these research projects dedicated to the advancement of musculoskeletal have gone on to garner additional funding from other trauma treatment. private and public agencies, and have resulted in The OTC Foundation recognizes the importance of multiple presentations and publications. We expect scientific discovery and has committed funding to that the results of this research will stimulate future promising research projects since its inception. In discoveries, and we look forward to the further disse- particular, the organization has supported the work of mination of this interesting work. young and less experienced investigators, as well as The OTC Research Committee (RECO) oversees this the scientific studies of established researchers and program which is supported by a grant from Stryker their teams. to the Foundation for this purpose. This book presents highlights of the basic and clinical TABLE OF CONTENTS PETER PATKA ESTHER VAN LIESHOUT THEODORE MICLAU Past President Scientific Coordinator President 2011- 2014 2 OTC RESEARCH COURSES OTC WORKSHOPS 2011-12 OTC WORKSHOPS 2013-14 BOOKS PUBLICATIONS PRESENTATIONS OTC RESEARCH PROGRAM OTC FOUNDATION AT A GLANCE OUTLOOK 2015-16 Research Program History ............................................................................................ 4 Research Committee Members ...................................................................................... 5 Supporting Researchers Worldwide ................................................................................. 6 Grant Application And Review Process ................................................................................ 7 Young Investigator Grants 2011 ..................................................................................... 8 Research Grants 2011 .............................................................................................. 12 Research Grants 2013 ............................................................................................. 22 Research Grants 2014 ............................................................................................. 24 OTC Research Courses 2011-2014 ................................................................................. 30 TABLE OF CONTENTS OTC „Hot Topics“ Workshops 2011-2012 .......................................................................... 32 OTC Workshops 2013-2014 ......................................................................................... 34 OTC RESEARCH PROGRAM Books .................................................................................................................. 36 Publications ........................................................................................................... 39 Presentations ......................................................................................................... 41 OTCF Research Program Outlook 2015-2016 ...................................................................... 48 2011- 2014 OTC Foundation at a glance ....................................................................................... 50 3 OTC RESEARCH PROGRAM 20011-14 RESEARCH PROGRAM HISTORY RESEARCH COMMITTEE MEMBERS SUPPORTING RESEARCHERS WORLDWIDE REVIEW PROCESS YOUNG INVESTIGATOR GRANTS 2011 RESEARCH GRANTS 2011-14 Research Program History The objective of Research Grants is to encourage investigators by providing seed and start-up funding for promising research projects in the field of ortho- paedic trauma surgery through Grants of up to US$ 50,000 for a research project extending over a maxi- mum of two years. The Mission of OTC is to foster evidence-based research that increases knowledge to solve clinical problems and improve orthopaedic trauma care. RESEARCH COMMITTEE 2014 Through the OTC Research Grant Program funding support is provided on topics such as: • Promotion of fracture healing, including treatment The evaluation and selection of grant projects is total grant volume. Therefore the OTC is not able to and enhancement of fracture repair strictly based upon blinded proposals submitted by fund all of the research proposals. The number of • Treatment of fractures in osteoporotic bone applicants, in accordance with OTA criteria. The OTC funded proposals varies from year to year depending • New technologies in fracture fixation, including Research Committee, with currently six members of on the availability of funds. computer-assisted surgery high academic standing, oversees and directs the • Prophylaxis and treatment of infections in fracture program. This committee identifies research topics to During the years 2005, 2006 and 2007 the Research • Prospective clinical trials in fracture care be covered, develops the procedures for reviewing Grants were administered by the AIOD. With the • Numerical methods in trauma surgery proposals, and establishes the criteria for approving transition from AIOD to the OTC Foundation at the • Translational, pre-clinical and experimental proposals and awarding grants. beginning of 2008, such grants are provided as OTC research Research Grants. The essence of the program has • Biomechanical studies Further information on the OTC Research Grant been maintained, including the Research Committee. Program can be obtained under Due to a transitional period for the OTC Foundation The target groups addressed through the program www.otcfoundation.org administration and governance in 2012 there were are senior researchers who are eligible to research by clicking on ‘Research Grants’. no research grants awarded in that year. The grant grants of up to US$ 50,000. Until 2011 also young program resumed in 2013 with the funding of three investigators were eligible who could obtain grants of The budget for OTC Grants is limited and applicant’s research projects per annum, and a streamlined ap- up to US$ 10,000. submissions are often three times higher than the plication and review process. 4 OTC RESEARCH COURSES OTC WORKSHOPS 2011-12 OTC WORKSHOPS 2013-14 BOOKS PUBLICATIONS PRESENTATIONS OTC RESEARCH PROGRAM OTC FOUNDATION AT A GLANCE OUTLOOK 2015-16 Research Committee Members VOLKER ALT, MD PHD, GERMANY Orthopaedic Trauma Surgeon (University Hospital Giessen, Giessen, Germany) PETER AUGAT, PHD, GERMANY Professor of Biomechanics (Institute of Biomechanics, Murnau, Germany) LOUIS WING-HOI CHEUNG, BSC PHD, CHINA (RECO MEMBER UNTIL 2012) Research Associate Professor, Deputy Director of Musculoskeletal Research Laboratory (Department of Orthopaedics&Traumatology, The Chinese University of Hong Kong, Hong Kong, China) SUNE B.A. LARSSON, MD, PHD, SWEDEN (RECO MEMBER AS OF 2014) Professor and Consultant in Orthopedic Surgery, Uppsala University Hospital, Sweden THEODORE MICLAU, III, MD, USA (RECO CHAIR AS OF 2011) Orthopaedic traumatologist, vice Chairman and Director of Orthopaedic Trauma (Dept. of Orthopaedic Surgery, University California San Francisco, San Francisco, USA) PETER PATKA, MD PHD, THE NETHERLANDS (RECO CHAIR UNTIL 2011) Rotterdam University Chair in Trauma Surgery (Dept. of Surgery-Traumatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands) A.H.R.W. SIMPSON, MD PHD, UK Professor of Orthopaedics and Trauma (Dept. of Orthopaedic Surgery, Royal Infirmary, Edinburgh, Scotland) ESTHER M.M. VAN LIESHOUT, PHD, THE NETHERLANDS (RECO SCIENTIFIC COORDINATOR) Research Coordinator in Trauma Surgery (Dept. of Surgery-Traumatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands) 5 OTC RESEARCH PROGRAM 20011-14 RESEARCH PROGRAM HISTORY RESEARCH COMMITTEE MEMBERS SUPPORTING RESEARCHERS WORLDWIDE REVIEW PROCESS YOUNG INVESTIGATOR GRANTS 2011 RESEARCH GRANTS 2011-14 Supporting Researchers Worldwide Through a Young Investigator Grant or a Research PROPOSALS AND GRANTS 2005-2014 Grant, OTC supported researchers active in areas related to trauma care: • For the 2011 grants, 29 Pre-proposal applications Number PRE-PROPOSALS were received and 16 were invited for submitting 60 a Full-length proposal. Of these, eight were FULL-PROPOSALS accepted, following a well-defined review and GRANTS AWARDED selection process. The approval rate was 50% 50 with a total amount of USD 270’722 granted • In 2012 the grant process was suspended for one year, and the pre-proposal step eliminated 40 • For the 2013 grants, 13 full proposals were received. Following the RECO review process, three were accepted. The approval rate was 30 23% with a total amount of USD 150’000 granted • For the 2014 grants, 10 full proposals were received. Of these, three were accepted with 20 a total amount of USD 150’000 representing an approval rate of 30% 10 • Currently, the OTC is following up on 16 unfinished grant projects from 2008 till 2014. Since its inception in 2005, the program awarded a total 0 USD 2’519’709 to research grant projects. Year 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 • Biological research in
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