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Open Access Publishing Series in PROJECT | Essays and Researches 2 PRO-INNOVATION PROCESS PRODUCTION PRODUCT Edited by Giuseppe De Giovanni Francesca Scalisi Open Access Publishing Series in PROJECT | Essays and Researches Editor in Chief Cesare Sposito (University of Palermo) International Scientific Committee Carlo Atzeni (University of Cagliari), Mario Bisson ( Polytechnic of Milano) , Tiziana Campisi (University of Palermo), Maurizio Carta (University of Palermo), Xavier Casanovas (Polytechnic of Catalunya), Giuseppe De Giovanni (University of Palermo), Clice de Toledo Sanjar Mazzilli (University of São Paulo), Giuseppe Di Benedetto (University of Palermo), Pedro António Janeiro (University of Lisbon), Massimo Lauria (University of Reggio Calabria), Francesco Maggio (University of Palermo), Renato Teofilo Giuseppe Morganti (University of L’Aquila), Frida Pashako (Epoka University of Tirana), Alexander Pellnitz (THM University of Giessen), Dario Russo (University of Palermo), Francesca Scalisi (DEMETRA Ce.Ri.Med.), Andrea Sciascia (University of Palermo), Paolo Tamborrini (Polytechnic of Torino), Marco Trisciuoglio (Polytechnic of Torino) Each book in the publishing series is subject to a double-blind peer review process In the case of an edited collection, only the papers of the Editors are not subject to the afore - mentioned process since they are experts in their field of study Volume 2 Edited by Giuseppe De Giovanni and Francesca Scalisi PRO-INNOVATION: PROCESS, PRODUCTION, PRODUCT Palermo University Press | Palermo (Italy) ISBN (print): 978-88-5509-052-0 ISBN (online): 978-88-5509-055-1 ISSN (print): 2704-6087 ISSN (online): 2704-615X Printed in August 2019 by Fotograph srl | Palermo Editing and typesetting by DEMETRA CE.R I.M ED .. on behalf of NDF Book cover and graphic design by Cesare Sposito Promoter DEMETRA CE.R I.M ED . -
Fibrous Tissue Ring: an Uncommon Cause of Severe Prosthetic Valve Stenosis
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector The Journal of Thoracic and Cardiovascular Surgery Brief communications 12 5 3 Volume 109, Number 6 FIBROUS TISSUE RING: AN UNCOMMON CAUSE OF SEVERE PROSTHETIC VALVE STENOSIS Paolo Masiello, MD, Vincenzo Cassano, MD, and Giuseppe Di Benedetto, MD, Salerno, Italy We describe here the case of a patient in whom severe mitral stenosis and periprosthetic leak developed 5 years after mitral valve replacement with a Medtronic Hall prosthesis (Medtronic, Inc., Minrie.apolis, Minn.). Mitral valve stenosis was attributed to the~formation of concen- tric dense fibrous tissue around the atrial side of the anulus. A 45-year-old woman underwent open mitral commis- surotomy in 1979 for rheumatic mitral stenosis. Ten years later she underwent mitral valve replacement with a Medtronic Hall 27 mm prosthesis. In 1993 she had a fever of unknown origin. Subsequently her clinical status pro- gressively worsened, with the onset of exertional dyspnea and fatigue. In March 1994 she was referred to us. On admission severe peripheral edema and jugular vein dis- tention were present. The liver was palpable 6 cm below the costal border. A 2/6 to 3/6 soft holosystolic murmur was audible on the apex radiating to the axilla. Blood pressure was 130/80 mm Hg. The electrocardiogram showed sinus rhythm with a heart rate of 96 beats/min and signs of moderate right ventricular hypertrophy. The chest x-ray film revealed a slightly enlarged cardiac shadow and pulmonary congestion. A transthoracic two-dimensional and Doppler echocardiogram showed left atrial dilatation, normal opening of the prosthesis, reduction of diastolic flow through the prosthesis, and a mild periprosthetic leak. -
PRELIMINARY PROGRAM Nov. 7Th,2016
PRELIMINARY PROGRAM Nov. 7th,2016 XXVIII° Congresso Nazionale Società Italiana di Cardiochirurgia Roma, 25-27Novembre, 2016 Ergife Palace Hotel TRANSLATIONAL CARDIOVASCULAR SCIENCE MEETS STANDARD AND INNOVATIVE THERAPIES PAROLE CHIAVE: Cardiochirurgia, educational, training, tecnica chirurgica. - Il congresso è destinato a professionisti medici chirurghi nel settore della Chirurgia cardiaca - Le ore formative previste sono: 31 Segreteria organizzativa G.C. Srl Via della Camilluccia 535 00135 - ROMA Tel + 39.06.85305059 E-mail: [email protected] 2 FRIDAY, NOV. 25TH TECHNO-GRADUATE: ADULT CARDIAC MAIN ROOM TECHNO-GRADUATE: ADULT CARDIAC SESSION 1 THE GREAT EVERLASTING DEBATE: STANDARD VS. LESS INVASIVE SURGERY CHAIR MICHELE DI MAURO (CHIETI) PIERSILVIO GEROMETTA (BERGAMO) 8.00 WHY I PREFER STANDARD CABG LORENZO MENICANTI (SAN DONATO M) 8.15 WHY I PREFER LESS INVASIVE CABG CLAUDIO MUNERETTO (BRESCIA) 8.30 FIVE MINUTES REBUTTAL MENICANTI - MUNERETTO 8.40 WHY I PREFER STANDARD AVR ROBERTO DI BARTOLOMEO (BOLOGNA) 8.55 WHY I PREFER LESS INVASIVE AVR MATTIA GLAUBER (MILANO) 9.10 FIVE MINUTES REBUTTAL DI BARTOLOMEO - GLAUBER 9.20 WHY I PREFER STANDARD MV PROCEDURES OTTAVIO ALFIERI (MILANO) 9.35 WHY I PREFER LESS INVASIVE MV PROCEDURES FRANCESCO MUSUMECI (ROMA) 9.50 FIVE MINUTES REBUTTAL ALFIERI - MUSUMECI 10.00-10.30 STANDS VISIT MAIN ROOM TECHNO-GRADUATE: ADULT CARDIAC SESSION 2 VALVES, VALVES, AND AGAIN VALVES! CHAIR MAURO RINALDI (TORINO) UGOLINO LIVI (UDINE) 10.30 PERCEVAL VALVE: FROM SELECTIVE TO ROUTINE USE GIOVANNI TROISE (BRESCIA) AVR WITH EDWARDS INTUITY ELITE: A REAL MINIMALLY INVASIVE 10.45 MARCO DI EUSANIO (ANCONA) APPROACH NEXT GENERATION OF SURGICAL AORTIC PERICARDIAL VALVE: AVALUS. 11.00 A. -
PASS Information Title Cilostazol Drug Utilisation Study
PASS Information Title Cilostazol drug utilisation study Protocol version Version 2 identifier Date of last version of February 28, 2013 protocol EU PAS register number Registration is planned prior to study initiation once the protocol is final and has received regulatory endorsement by the Committee for Medicinal Products for Human Use (CHMP) Active substance Cilostazol, ATC code B01AC23, Platelet aggregation inhibitors excluding heparin Medicinal product Pletal, Ekistol Product reference UK/H/0291/001 and 002 Procedure number EMEA/H/A-31/1306 Marketing authorisation Otsuka Pharmaceutical Europe Ltd. holder(s) (MAH) Lacer S.A. Joint PASS No Research question and This study protocol was developed in the context of the European objectives Medicines Agency (EMA) referral (article 31 of Council Directive 2001/83/EC) on the risks and benefits of the use of cilostazol. The study objectives are to characterise patients using cilostazol according to demographics, comorbidity, comedications, and duration of treatment. In addition, the study will describe the dosing of cilostazol, the prescribing physician specialties, and the potential off-label prescribing. Country(-ies) of study Spain, United Kingdom, Germany, Sweden Author Jordi Castellsague, MD, MPH; Cristina Varas-Lorenzo, MD, MPH, PhD; Susana Perez-Gutthann, MD, MPH, PhD RTI Health Solutions Trav. Gracia 56 Atico 1 08006 Barcelona, Spain Telephone: +34.93.241.7766 Fax: +34.93.414.2610 E-mail: [email protected] CONFIDENTIAL 1 of 56 Marketing Authorisation Holder(s) Marketing authorisation -
Bref Historique De La Faculté De Médecine De L'université Mcgill
HISTOIRE DE MÉDECINE ET DES SCIENCES LA médecine/sciences 1997; 13: 568-74 ---�� det4 Bref historique � de la Faculté de Médecine et de4 de l'Université McGill s� 'histoire de la médecine à Mont cliniques. L'Hôpital général de Mont L réal est intimement liée à l'his réal (figure 4) accueillait les étudiants, toire de l'Université McGill. Au une attitude assez novatrice à l'époque début du XJXe siècle, l'Hôtel-Dieu de en Amérique du Nord. Montréal, créé dès 1644, deux ans Dès le début, on attacha beaucoup après la fondation de la ville, ne pou d'importance à la recherche. En vait accueillir que trente patients [1] 1848, on expérimenta l'administra et ne suffisait pas à recevoir tous les tion de l'éther et l'année suivante on malades qui se présentaient à lui. Par l'utilisa en clinique à l'Hôpital géné ailleurs, aucun hôpital ne desservait la ral de Montréal. Depuis lors, cet hô population anglophone. En 1801, le pital soutient des activités de re Figure 1. Burnside Place, la propriété parlement de Québec institua, en ré cherche. En 1855, Sir William de campagne de James McGi/1, dessi ponse aux pressions de la communau Dawson, géologue de renom, devint, née par W.D. Lambe en 1842. La mai té anglophone de Montréal, la Royal son, située près d'un ruisseau (burn en à l'âge de 35 ans, recteur de l'Univer Institution for the Advancernent of Lear anglais) se trouvait au sud de Roddick sité McGill (figure 5). Durant son rec ning, une institution protestante des Gates, l'entrée principale actuelle de torat qui dura jusqu'en 1893, il tinée à promouvoir l'éducation l'Université (Archives photographiques transforma une petite institution victo secondaire et supérieure dans la pro Notman, Musée McCord, Montréal). -
Calendar Is Brought to You By…
A Celebration of Canadian Healthcare Research Healthcare Canadian of Celebration A A Celebration of Canadian Healthcare Research Healthcare Canadian of Celebration A ea 000 0 20 ar Ye ea 00 0 2 ar Ye present . present present . present The Alumni and Friends of the Medical Research Council (MRC) Canada and Partners in Research in Partners and Canada (MRC) Council Research Medical the of Friends and Alumni The The Alumni and Friends of the Medical Research Council (MRC) Canada and Partners in Research in Partners and Canada (MRC) Council Research Medical the of Friends and Alumni The The Association of Canadian Medical Colleges, The Association of Canadian Teaching Hospitals, Teaching Canadian of Association The Colleges, Medical Canadian of Association The The Association of Canadian Medical Colleges, The Association of Canadian Teaching Hospitals, Teaching Canadian of Association The Colleges, Medical Canadian of Association The For further information please contact: The Dean of Medicine at any of Canada’s 16 medical schools (see list on inside front cover) and/or the Vice-President, Research at any of Canada’s 34 teaching hospitals (see list on inside front cover). • Dr. A. Angel, President • Alumni and Friends of MRC Canada e-mail address: [email protected] • Phone: (204) 787-3381 • Ron Calhoun, Executive Director • Partners in Research e-mail address: [email protected] • Phone: (519) 433-7866 Produced by: Linda Bartz, Health Research Awareness Week Project Director, Vancouver Hospital MPA Communication Design Inc.: Elizabeth Phillips, Creative Director • Spencer MacGillivray, Production Manager Forwords Communication Inc.: Jennifer Wah, ABC, Editorial Director A.K.A. Rhino Prepress & Print PS French Translation Services: Patrice Schmidt, French Translation Manager Photographs used in this publication were derived from the private collections of various medical researchers across Canada, The Canadian Medical Hall of Fame (London, Ontario), and First Light Photography (BC and Ontario). -
·Osler·Lbrary·Newsl Tter
THE ·OSLER·LI BRARY·NEWSLE TTER· NUMBER 103 · 2005 Osler Library of the History of Medicine, McGill University, Montréal (Québec) Canada • IN THIS ISSUE THE CUSHING – CAMAC CORRESPONDENCE THIS SPRING THE AMERICAN OSLER SOCIETY n 1980 Jack McGovern and I held its thirty-fifth annual meeting in Pasadena, published a book we called Student California, to honour the career of Dr. Earl Nation, I and Chief; the Osler-Camac Corres- pondence. In the introduction it was urologist, medical historian, Charter Member of the explained that C.N.B. Camac’s American Osler Society, and a dynamic Oslerian who papers, collected in three large this year celebrates his 95th birthday. Long familiar to the scrapbooks, are in the Huntington Osler staff, Dr. Nation has published four books about Library. In addition to the Osler William Osler, including the two volume An Annotated letters, and many other things, there are several letters from Harvey Checklist of Osleriana, plus about 300 articles on the topics Cushing. These reflect a friendship of urology, chemistry, history and humanism. To underline going back to their days in training his publications, Dr. John Carson recently compiled An at Johns Hopkins. Unfortunately, Annotated Checklist of Nationiana. In our newsletter Dr. Nation Camac kept few copies of his own turns his attention to a series of letters, (which narrowly letters. escaped destruction) between Osler’s biographer Dr. One charming note from Cushing to Camac is not there but is found in Harvey Cushing, (1869-1939) and Dr. Charles Camac, John Fulton’s biography of Cushing (1868-1940) who in 1896 became Osler’s Assistant (p. -
Spring 2007 (PDF)
UNIVERSITY OF TORONTO THE surgical spotlight ON ALUMNI, FACULTY, RESIDENTS & FRIENDS OF THE DEPARTMENT O F S U R G E R Y SPRING 2007 Lee Errett Receives the i n s i d e Norman Bethune Prize From the CHAIR’S COLUMN 3 Chinese Medical Association TRAUMA AS A COMPONENT OF CRITICAL CARE 5 PROGRESS ON WAIT TIMES 6 HOW ISCHEMIA HELPS THE HEART 8 “ALL SURGERY SHOULD BE DONE THROUGH MINIMAL ACCESS INCISIONS” KERGIN LECTURE 10 SCIENTISTS IN SURGERY 11 Dr. Norman Bethune performing surgery in an unused Buddhist temple in central Hopei, China, Spring NEW STAFF 12 1939. Source: Library and Archives Canada/Credit: National Film Board/Canadian Government Motion Picture Bureau/PA-114795 Norman Bethune, born in Gravenhurst, Ontario in 1890 and a graduate of the LEADERSHIP IN NEUROSURGERY 14 University of Toronto medical school, was a “restless, reckless, driven, energetic, enthusiastic and widely-sung hero” of thoracic surgery. He was a gifted muralist, EDITOR’S COLUMN 15 poet and romantic adventurer, who tried to cure tuberculosis using surgical treat- ment and radical reform of the social conditions responsible for its spread. Lloyd McLean, formerly Chair of Surgery at McGill, describes him vividly, including his HONOURS / AWARDS 16 scandalizing decision to join the Communist Party in Montreal, his development of the first mobile blood transfusions service during volunteer service in the Spanish GRANTS / FELLOWSHIPS 18 Civil War, and his heroic contributions in China. Here is a quote from that descrip- tion and a picture of Bethune operating in an unused Buddhist temple in 1939. continued on page 2 SURGICAL SPOTLIGHT S P R I N G 2 0 0 7 “During his 19 months in China, Bethune taught the Chinese skills and gave them hope. -
Bethune Foundation Fonds
The Osler Library of the History of Medicine McGill University, Montreal, Canada Osler Library Archive Collections P132 BETHUNE FOUNDATION FONDS COMPLETE INVENTORY LIST This is a guide to one of the collections held by the Osler Library of the History of Medicine, McGill University. Visit the Osler Library Archive Collections homepage for more information Bethune Foundation Fonds – P132 – Complete Inventory List P132: BETHUNE FONDATION FONDS TITLE: The Bethune Foundation Fonds DATES: 1967? - 1995 EXTENT: 60 cm of textual records. – 104 photographs. – 23 photographic negatives. – 2 audio cassettes. – 6 video cassettes. Biographical Sketch: The Bethune Foundation, first known as the Bethune Memorial Committee, was established at a meeting of Dr. Norman Bethune’s former friends, colleagues and admirers held at McGill University. The objectives were to perpetuate and expand his memory among Canadians by drawing attention to his humanitarian contributions in Canada, Spain and China. The first Chairman was Hazen Sise who was with Dr. Bethune in Spain where he organized the first successful mobile blood transfusion service during the Spanish Civil War. The Honorary Chairman was Dr. Wilder Penfield, Director of the Montreal Neurological Institute. Custodial History: Old accession number 869, plus other material donated by Andree Levesque. Scope and Content: The collection consists of documents such as meeting minutes, correspondence, speeches and financial records, photographs, and audio and video recordings generated by the official activities of the Bethune Foundation. Also included are items relating to Dr. Norman Bethune and to China, or Chinese medicine, such as newspaper clippings, printed material from China, photographs, and biographical sketches of Dr. Bethune. -
Downloaded 09/26/21 02:12 PM UTC 2015 AANS Annual Scientific Meeting: Oral Presentations
Oral Presentations 2015 AANS Annual Scientific Meeting Washington, DC • May 2–6, 2015 (DOI: 10.3171/2015.8.JNS.AANS2015abstracts) 500. Pre‑ and Postoperative Skin Preparation Using past decade. Diagnosis related group‑associated variables assessed Chlorhexidine‑Alcohol in Patients Undergoing Lumbar within our analysis included for traumatic stupor and coma 1) total Instrumented Fusion: Results of a Novel Antisepsis Protocol number of discharges, 2) length of stay, 3) charges, and 4) hospital type. Peter C. Gerszten, MD, MPH, FAANS; Erin Paschel; Ramesh Results: In 1997, there were a recorded 18,891 discharges Grandhi, MD; David Okonkwo, MD, PhD; Adam Kanter, MD; for the treatment of traumatic stupor and coma nationally (2:1, Yue‑Fang Chang, PhD (Pittsburgh, PA) male:female ratio). The majority of children treated were at teaching institutions (60.0%) in large metropolitan centers (92.6%). 52.6% Introduction: Wound infection following lumbar instrumented of cases received care at a designated children’s hospital. Median fusion surgery is a potentially preventable complication that is length‑of‑stay was 1.0 days and median charges totaled $3,919. associated with major morbidity and cost. The purpose of this In comparison, 14,778 pediatric patients were treated for the same investigation was to demonstrate that the postoperative application presentation in 2012 (2.2:1, male:female ratio). Similar trends were of a skin antiseptic agent in addition to standard preoperative skin noted in the presentation to predominantly large, metropolitan preparation reduces surgical site infection. The study was also teaching institutions. However, only one‑quarter of such cases designed to identify risk factors for the development of infection in received care at a designated children’s hospital. -
Aortic Valves WORKSHOP PRELIMINARY PROGRAMME
13th - 15th JUNE 2013 The ‘Less’ Aortic Valves WORKSHOP PRELIMINARY PROGRAMME Forum Guido Monzani • Centro di Formazione e Cultura • Via Aristotele, 33 • Modena • Italy THE ‘LESS’ AORTIC VALVES WORKSHOP Hesperia Hospital Davide Gabbieri Modena, Italy Hesperia Hospital Modena, Italy Filippo Benassi Azienda Ospedaliero Universitaria di Parma Parma, Italy Clorinda Labia Hesperia Hospital Modena, Italy Guglielmo Stefanelli Emanuela Angeli Hesperia Hospital University of Bologna Modena, Italy Bologna, Italy Guglielmo Stefanelli ESCVS - European Society for Hesperia Hospital Cardiovascular and Endovascular Surgery Modena, Italy SICCH - Italian Society for Cardiac Surgery Josè Luis Pomar EACTS - European Association Hospital Clínico for Cardio-Thoracic Surgery University of Barcelona Barcelona, Spain University of Bologna Regione Emilia-Romagna Roberto Di Bartolomeo Policlinico S.Orsola-Malpighi Comune di Modena University of Bologna Bologna, Italy UNDER REQUEST * 2 13th > 15th JUNE 2013 The ‘Less’ Aortic Valves WORKSHOP ‘Less’ aortic valve symposium is a two-days interactive workshop focused on stentless aortic prostheses, sutureless aortic valves and stentless aortic valved conduits. During the course a faculty of world leaders in the field will discuss and analyze with you the outcomes and problems related to the 1st generation porcine stentless aortic valves and the advantages of the pericardial stentless prostheses, along with the more appropriate techniques of implant. Theoretical and practical benefits of sutureless aortic implants will be reported, particularly in minimally-invasive approaches. The final topic concern the results reported by different experiences with the use of biological materials in surgery of the aortic root and Bentall operations with stentless conduits. During a two- hours lunch video session, twelve 5’ videos followed by 5’ discussion, collected by the scientific committee will be chosen, illustrating interesting case-reports or details of innovative surgical techniques. -
Human Respiratory Epithelium: Control of Ciliary
iiiiii mi i ii m i n i m m i i l l i n i u m iiiii 2807400791 HUMAN RESPIRATORY EPITHELIUM: CONTROL OF CILIARY ACTIVITY AND TECHNIQUES OF INVESTIGATION by Giuseppe Di Benedetto MEDICAL LIBRARY. ROYAL FREE HOSPITAL HAMPSTEAD. A thesis submitted for the degree of Doctor of Philosophy in the University of London Department of Thoracic Medicine Royal Free Hospital and School of Medicine September 1990 1 ProQuest Number: 10631083 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a com plete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest ProQuest 10631083 Published by ProQuest LLC(2017). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States C ode Microform Edition © ProQuest LLC. ProQuest LLC. 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106- 1346 ^OS 1 ^ ABSTRACT In man, most of the upper airways and the tracheo-bronchial tree down to the non alveolar walls of the respiratory bronchioles are covered by ciliated epithelium. Mucociliary clearance is the most important clearing mechanism of the respiratory tract and is the result of beating cilia propelling the overlying secretions, carrying both trapped inhaled material and locally produced biological debris, toward the oropharynx. The rate of mucus transport is determined by the power produced by each cilium and the number of cilia in contact with the mucus.