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REVI EW ARTICLES t The usefulness of biomarkers of airway inflammation in managing asthma Patil and Long ORIGINAL ARTICLES t Efficacy and safety of mometasone furoate/formoterol 200/10 mcg combination treatment in patients with persistent asthrna previously on mediurn-dose ICSs Nathan el al t Efficacy and safety of mometasone furoate/formoterol 200/10 mcg and 400/10 mcg combination treatments in patients with persistent asthma previously on high-dose ICSs Weinstein et al t Levocetirizine dihydrochloride in pedía trie allergic rhinitis or chronic urticaria Hampel et al t Oral olopatadine hydrochloride for the treatment of SAR Yamamoto et al t Epinephrine auto-injector use in a V.A. population Amirzadeh et al t Repeat epinephrine treatment for food-related allergic reactions Banerji et al t Reduced clinic, ER and hospital utilization after home environmental assessment Barnes et al t Immunotherapy for treatment of allergic asthma in children Alzakar nnd Alsamarai t Acetaminophen for preventing rnood and rnemory effects of prednisone Brown et al t Irnportant Florida botanical aeroallergens Pl1illips et al , t Atmospheric pollen count in Monterrey, Mexico Gonzalez-Diaz et al t DNA repair gene XRCCl polymorphisms and the risk of asthma Batar et nl t POPS Case: A 41-year-old male with cough, wheeze, and dyspnea poorly responsive to asthma therapy Ricketti et al ALLERGY and ASTHMA PROCEEDINGS Editor-in-Chief: Joseph A. Bellanti, MD Associate Editor: Russell A. Settipane, MD Executive Editorial Board American Board Members: Sami L. Bahna, MD Lawrence D. Frenkel, MD Kevin McGrath, MD Shreveport, LA Rockford, IL Fairfield, CT William Berger, MD Marianne Frieri, MD Christopher C. Randolph, MD Mission Viejo, CA East Meadow, NY Waterbury, CT Michael Blaiss, MD Sandra Gawchik, DO Diane E. Schuller, MD Memphis, TN Chester, PA Hershey, PA Malcolm Blumenthal, MD StanJey Goldstein, MD Robert J. Settipane, MD Minneapolis, MN Rockville Centre, NY Providence, RI Wamer W. Carr, MD Daniel Hamilos, MD Charles J. Siegel, MD Glenwood, MD Boston, MA Kansas City, MO Bradley Chipps, MD Bettina C. Bilman, MD Ronald Simon, MD Sacramento, CA Tyler, TX LaJolla, CA Linda S. Cox, MD Richard Honsinger, MD Raymond G. Slavin, MD Fort Lauderdale, FL Los Alamos, NM St. Louis, MO Timothy Craig, DO Donald E. Klein, MD Ricardo U. Sorenson, MD Hershey, PA Providence, RI New Orleans, LA Andrew Davidson, MD David M. 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Pohunek, MD PhD San Juan, Philipines Sweden Czech Republic Ale¡andro Escobar, PhD Matti Korppi, MD PhD Kostas Priftis, MD PhD Mexico City, Mexico Koupio, Finland Alhens, Greece Alessandro Fiocchi, MD PhD Marek L. Kowalski, MD Johannes Ring, MD PhD Milano, Italy Lodz, Poland Germany S.rndra N. Gonzalez Diaz, MD Mario LaRosa, PhD J. Rosado-Pinto PhD Monterrey, Mexico Catania, Italy Lisbon, Portugal Scction Editors Cli11ical Pearls and Pitfalls "POPS" Case Reports W.1m1:r W Carr, MD )o<:eph A. Bellantí, MO Editorial/Publishing Staff: Sus.rn Colucci, Ginny Loiselle, and Diane Zerba. Advertising Rep: Jim Brady, James T. Brady, lnc. (516-742-7960), [email protected]. Comrnercial Reprints: Contact Mrnna Burgess, Sales Director, Cadmus Communications, 443-527-3855 or email [email protected]. Participating Societies Arizona Allergy and Asthma Massachusetts Allergy & Asthma Oregon Society of Allergy, Asthma, Society Society and Immunology President: Miriam Anand, MD President: James A. Maclean, MD President: Jason Friesen, MD Allen Cazort Allergy Society of Pennsylvania Allergy and Asthma Arkansas Michigan Allergy and Asthma Society President: Gail Cookingham, MD Association President: Blake G. Scheer, MD President: Janet L. Beausoleil, MD Buffalo Allergy Society President: Mark Sands, MD Mid-South Allergy Forum Rhode Island Society of Allergy President: Joseph S. Fahhoum, MD President: Russell A. Settipane, MD Eastem Allergy Conference Director: Russell A. Settipane, MD Missouri State Allergy Association South Carolina Allergy, Florida Allergy, Asthma, & President: Mark L. Vandewalker, MD Asthma, and Imrnunology Society Immunology Society President: Emmanuel D. Sarmiento, M President: Frank J. Eidelman, MD Nebraska Allergy, Asthma and Immunology Society South Dakota Allergy Society Allergy / Asthma/Immunology Society President: Againdra Bewtra, MD President: Mark Bubak, MD of Georgia President: Caro! A. Wiggins, MD Southwest Allergy Forum New England Society of Allergy Director: Agile Redmon, MD Greater Washington Asthma Allergy President: Mitchell R. Lester, MD and Immunology Society President: Richard R. Rosenthal, MD Tennessee Allergy, Asthma, and New Hampshire Allergy Society lmmunology Society Illinois Society of Allergy, Asthma and President: Ashok Shah, MD President: John P. Overholt, MD Immunology President: Giselle Mosnairn, MD New Jersey Society of Allergy, Texas Allergy, Asthma, & Asthma, and Immunology Immunology Society lowa Society of Allergy and President: Stuart L. Abramson, MD Immunology President: Michael B. Sherman, MD President: Francisco G. Peralta, MD Asthma and Allergy Society of Kentucky Society of Allergy, Asthma New Mexico Allergy Society Virginia and Clinical Immunology President: James H. Sussman, 00 President: Craig Koenig, MD President: Tao Le, MD New York State Society of Allergy, Washington State Society of Allergy. Long Island Allergy and Asthma Asthma & Immunology Asthma, and Immunology Society President: Robert N. Corriel, MD President: Mary Farrington, MD President: Muataz Jaber, MD Oklahoma Allergy Society Western Society of Allergy, Asthma, Louisiana Allergy, Asthma, and President: Suzanne Olive, MD Immunology Society and Immunology President: Laurianne G. Wild, MD President: William E. Berger, MD Orange County (CA) Allergy, Asthma & Maine Society of Allergy Immunology Society Wisconsin Allergy Society President: Matthew Aresery, MD President: Geeta Venkat, MD President: Susan Higgins-Larkey, M Copyright Disclosure & onlin~) NDICA Allergy Asthma Proceedings (ISSN 1088-5412 Erint, ISSN 1539-§3__94 is owned and published bi-monthly by OceanSide Publications, Inc., 95 Pitman Street, Prov1aeñee,ltr 02906. Single copies: $25 (add $5 shipping within the USA, S 'ATANfl for outside USA address); 2010 Subscriptions: $189 per year domestic, see complete price options in reader services. Email MPOR [email protected]. Copyright© 2010, OceanSide Publications, Inc. (401-331-2510; Fax 401-331-0223). Printed in the USA. All rights reserved. t Vamir part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical photocopying, recording, or otherwise, without prior written permission from the publisher. Statements and opinions expressed in articles and communications herein are those of the author(s) and not necessarily those of the Editor(s), publisher, the American Association of Certified Allergists (AACA), or the affiliated regional, state, and local allergy societies. The Editor(s), publisher, the American Association of Certified Allergists (AACA), and the affiliated regional, state, and local allergy societies disclaim any responsibility or liability for such material and do not losing guarantee, warrant, or endorse any productor service in this publication, nor do they guarantee any claim made by the manufacturer of such productor service. Allergy and Asthma Proceedings is registered with Copyright Clearance Center, Inc 222 Rosewood Drive, Danvers, MA 01923. To get permission to use copyrighted material from this publication, go to www.copyright.coro. tdvers 1fectic Al TABLE OF CONTENTS Vol. 31, No. 4 July-August 2010 Review Article 259 The usefulness of biomarkers of airway inflammation in managing asthma S. U. Patil ~d A. A. Long Original Articles 269 Twenty-six-week efficacy and safety study of mometasone furoate/formoterol 200/10 µg combination treatment in persistent asthmatic patients previously receiving medium-dose inhaled corticosteroids R. A. Nathan, H. Nolte, and D. S. Pearlman, on Behalf of the P04334 Study Investigators 280 Twelve-week efficacy and safety study of mometasone furoate/formoterol 200/100 µg and 400/10 µg combination treatments in patients with persistent asthma previously receiving high-dose inhaled corticosteroids S. F. Weinstein, J. Corren, K. Murphy, H. Nolte, and M. White, on Behalf of the Study Investigators of P04431 290 Safety and tolerability of levocetirizine dihydrochloride in infants and children with allergic rhinitis or chronic urticaria F. Hampel, P. Ratner, and J.-M. C. Haeusler 296 Efficacy of oral olopatadine hydrochloride for the treatment of seasonal