University of Southern , , University of Michigan, Ann Arbor, and Odense University Hospital, Master Class in Thyroid Eye Disease Odense, Denmark, Friday 31 May - Saturday 1 June, 2013

Date: Friday 31 May, 9 A.M. - Saturday 1 June, 3 P.M., 2013 Location: Kløvervænget 6, ground floor, Odense University Hospital, DK-5000 Odense, Denmark Fee: 1500 Danish kroner. This fee covers course materials and refreshments (coffee breaks and lunch, both days; dinner on the Friday) Registration: On a first come basis, and limited to 25 participants. Copying the link below into your browser will lead you to the home page with further information on registration and links to a range of hotels. http://www.sdu.dk/Om_SDU/Institutter_centre/Klinisk_institut/Forskning/Kurser/Master+Class+in+Thyroid+ Eye+Disease

Course language: English Faculty: • Professor Laszlo Hegedüs, Dept. Endocrinology, University of Southern Denmark • Professor Terry J. Smith, Dept. Ophthalmology and Visual Sciences, University of Michigan • Associate professor Ray Douglas, Dept. Ophthalmology and Visual Sciences, University of Michigan • Associate professor Thomas H. Brix, Dept. Endocrinology, University of Southern Denmark • Associate professor Steen J. Bonnema, Dept. Endocrinology, University of Southern Denmark • Doctor Nico Gampenrieder Grosen, Dept. Ophthalmology, University of Southern Denmark

Programme: Friday 31 May 2013 09.00-09.15 Introduction of programme, scope, and speakers (LH & TJS) 09.15-09.30 Pre-course questionnaire (LH) 09.30-10.15 Epidemiology, genetic and environmental contributors in Graves’ disease (GD) and thyroid eye Disease (TED) (THB) 10.15-10.30 Coffee break 10.30-11.30 Pathophysiology of GD and TED (TJS) 11.30-12.15 Clinical evaluation of GD, therapy options (SJB) 12.15-13.30 Lunch 13.30-14.00 TED; Clinical characteristics, determination of activity and severity (RD) 14.00-16.00 Interactive clinical case presentations. Small group discussions with an endocrinologist and an ophthalmologist. Training in assessing activity and severity (Faculty) 16.00-16.15 Coffee break 16.15-17.00 Treating GD in the presence of TED (LH) 17.00-17.30 Questions and answers in relation to the day’s topics and the morning questionnaire (Faculty) 19.00-22.00 Dinner

Saturday 1 June 2013 Management of TED 08.30-09.00 Supportive care (NGG) 09.00-09.30 Corticosteroids and cyclosporine (THB) 09.30-10.00 Orbital irradiation (SJB) 10.00-10.15 Coffee break 10.15-10.45 Role of emerging immunotherapy and selenium (TJS) 10.45-11.30 Decompression surgery (RD) 11.30-12.15 Strabismus and eyelid surgery (RD) 12.15-13.00 Lunch 13.00-14.30 Interactive clinical case presentations. Small group discussions with endocrinologist and ophthalmologist. Focus on therapy options (Faculty) 14.30-15.00 Questions and answers. Course evaluation (Faculty) 15.00 End of course. Certificates of attendance