AWH Pregnancy Confirmation Handout
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Pre-Term Pre-Labour Rupture of Membranes and the Role of Amniocentesis
Fetal and Maternal Medicine Review 2010; 21:2 75–88 C Cambridge University Press 2010 doi:10.1017/S096553951000001X First published online 15 March 2010 PRE-TERM PRE-LABOUR RUPTURE OF MEMBRANES AND THE ROLE OF AMNIOCENTESIS 1,2 ANNA P KENYON, 1,2 KHALIL N ABI-NADER AND 2 PRANAV P PANDYA 1Elizabeth Garrett Anderson Institute for Women’s Health, University College London, 86-96 Chenies Mews, London WCIE 6NX. 2Fetal Medicine Unit, University College London Hospitals NHS Foundation Trust, 235 Euston Rd, London NWI 2BU. INTRODUCTION Pre-labour premature rupture of membranes (PPROM) is defined as rupture of membranes more than 1 hour prior to the onset of labour at <37 weeks gestation. PPROM occurs in approximately 3% of pregnancies and is responsible for a third of all preterm births.1 Once membranes are ruptured prolonging the pregnancy has no maternal physical advantage but fetal morbidity and mortality are improved daily at early gestations: 19% of those infants born <25 weeks develop cerebral palsy (CP) and 28% have severe motor disability.2 Those infants born extremely pre term (<28 weeks) cost the public sector £75835 (95% CI £27906–145508) per live birth3 not to mention the emotional cost to the family. To prolong gestation is therefore the suggested goal: however how and why might we delay birth in those at risk? PPROM is one scenario associated with preterm birth and here we discuss the causative mechanisms, sequelae, latency, strategies to prolong gestation (antibiotics) and consider the role of amniocentesis. We will also discuss novel therapies. PATHOPHYSIOLOGY OF MEMBRANE RUPTURE The membranes, which act to protect and isolate the fetus, are composed of two layers. -
Pregnant Body Book
THETHE COMPLETECOMPLETE ILLUSTRATEDILLUSTRATED GUIDEGUIDE FROMFROM CONCEPTIONCONCEPTION TOTO BIRTHBIRTH THE PREGNANT BODY BOOK THE PREGNANT BODY BOOK DR. SARAH BREWER SHAONI BHATTACHARYA DR. JUSTINE DAVIES DR. SHEENA MEREDITH DR. PENNY PRESTON Editorial consultant DR. PAUL MORAN GENETICS 46 THE MOLECULES OF LIFE 48 HOW DNA WORKS 50 PATTERNS OF INHERITANCE 52 GENETIC PROBLEMS AND 54 INVESTIGATIONS THE SCIENCE OF SEX 56 THE EVOLUTION OF SEX 58 ATTRACTIVENESS 62 HUMAN PREGNANCY 6 DESIRE AND AROUSAL 64 THE EVOLUTION OF PREGNANCY 8 THE ACT OF SEX 66 MEDICAL ADVANCES 10 BIRTH CONTROL 68 IMAGING TECHNIQUES 12 GOING INSIDE 14 CONCEPTION TO BIRTH 70 TRIMESTER 1 72 ANATOMY 24 MONTH 1 74 BODY SYSTEMS 26 WEEKS 1–4 74 THE MALE REPRODUCTIVE SYSTEM 28 MOTHER AND EMBRYO 76 THE PROSTATE GLAND, PENIS, 30 AND TESTES KEY DEVELOPMENTS: MOTHER 78 MALE PUBERTY 31 CONCEPTION 80 HOW SPERM IS MADE 32 FERTILIZATION TO IMPLANTATION 84 THE FEMALE REPRODUCTIVE SYSTEM 34 EMBRYONIC DEVELOPMENT 86 THE OVARIES AND FALLOPIAN TUBES 36 SAFETY IN PREGNANCY 88 THE UTERUS, CERVIX, AND VAGINA 40 DIET AND EXERCISE 90 THE BREASTS 42 MONTH 2 92 FEMALE PUBERTY 43 WEEKS 5–8 92 THE FEMALE REPRODUCTIVE CYCLE 44 MOTHER AND EMBRYO 94 CONTENTS london, new york, melbourne, DESIGNERS Riccie Janus, ILLUSTRATORS munich, and dehli Clare Joyce, Duncan Turner DESIGN ASSISTANT Fiona Macdonald SENIOR EDITOR Peter Frances INDEXER Hilary Bird CREATIVE DIRECTOR Rajeev Doshi SENIOR ART EDITOR Maxine Pedliham SENIOR 3D ARTISTS Rajeev Doshi, Arran Lewis PICTURE RESEARCHERS Myriam Mégharbi, 3D ARTIST Gavin Whelan PROJECT EDITORS Joanna Edwards, Nathan Joyce, Karen VanRoss Lara Maiklem, Nikki Sims ADDITIONAL ILLUSTRATORS PRODUCTION CONTROLLER Erika Pepe Peter Bull Art Studio, Antbits Ltd EDITORS Salima Hirani, Janine McCaffrey, PRODUCTION EDITOR Tony Phipps Miezan van Zyl DVD minimum system requirements MANAGING EDITOR Sarah Larter PC: Windows XP with service pack 2, US EDITOR Jill Hamilton MANAGING ART EDITOR Michelle Baxter Windows Vista, or Windows 7: Intel or AMD processor; soundcard; 24-bit color display; US CONSULTANT Dr. -
New Parents' Guide
New Parents’ Guide Created in collaboration with The Childbirth Education Association of Cincinnati 1 Congratulations! Congratulations on your pregnancy! Whether you’ve been planning for years or you received a happy surprise, we’re honored and excited to support you through one of the most unique and exciting chapters in your life. You may feel a range of emotions about becoming a mom (anxious, eager, scared), and you’ll probably have some questions along the way. Together with the Childbirth Education Association, we’ve compiled the information and resources you need to feel confident and prepared when your new baby arrives. We want to help you navigate your pregnancy journey with as little stress as possible, so you can focus on what matters most: welcoming your new baby with Childbirth Education Video joy and love. Series To help families prepare for everything from pregnancy to postpartum, Pampers developed a nine-part Childbirth Education Video Series to help supplement this guide. Visit Pampers.com to learn more. 2 SECTION 1: What to Expect During Pregnancy Your Baby’s Development (by trimester) First Trimester (1-12 Weeks) In the weeks following conception, your baby starts to develop its brain, spinal cord, heart and other organs. • The neural tube along your baby’s back starts to close, forming a C-shape along the spine 1and giving it a curve that your baby will maintain for much of the pregnancy. • Structures in and around your baby’s head and nose form, like the eyes and ears. • The eyelids and external ears continue to develop while your baby’s length increases to First Trimester about 2 ½ inches. -
Symphysio Fundal Height (SFH) Measurement As a Predictor of Birth Weight
Faridpur Med. Coll. J. 2012;7(2):54-58 � Original Article Symphysio Fundal Height (SFH) Measurement as a Predictor of Birth Weight Z Parvin1, S Shafiuddin2, MA Uddin3, F Begum4 Abstract : Fetal weight is a very important factor to make a decision about labor and delivery. Assuming that in large fetuses, dystocia and other complications like cerebral edema, neurological damage, hypoxia and asphyxia may result during or after the delivery. On the other hand, one of the causes of high perinatal mortality in our country is high rate of low birth weight. Rural people may not have access to ultrasonography which is one of the methods to predict birth weight. For these people alternative easy method is necessary. So we can assess fetal birth weight by measuring symphysio-fundal height. Total 100 consecutive pregnant women of gestational age more than 32 weeks admitted for delivery in the Obstetric and Gynaecology department of Faridpur General Hospital were the subject of this study. After selection of cases, a thorough clinical history was taken and elaborate physical examination was done. Common criteria for collection of data were followed in every case. The fetal weight estimated by Johnson's formula was recorded in the predesigned data sheet and then was compared with birth weight following delivery of the fetus. Collected data were compiled and relevant statistical calculations were done using computer based software. Statistical tests (Correlation) were done between actual birth weight (taken as dependant variable) and fetal weight (found by Johnson's Formula), symphysio fundal height (SFH), pre-delivery weight and height of the patients (taken as independent variables) and the tests revealed that actual birth weight was significantly correlated with fetal weight (found by Johnson's Formula), SFH, pre-delivery weight and height of the patients. -
Magnetic Resonance Imaging
Published online: 2021-07-30 OBS/GYNEC Magnetic resonance imaging ‑ A troubleshooter in obstetric emergencies: A pictorial review Rohini Gupta, Sunil Kumar Bajaj, Nishith Kumar, Ranjan Chandra, Ritu Nair Misra, Amita Malik, Brij Bhushan Thukral Department of Radiodiagnosis, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India Correspondence: Dr. Rohini Gupta, Department of Radiodiagnosis, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi ‑ 110 029, India. E‑mail: [email protected] Abstract The application of magnetic resonance imaging (MRI) in pregnancy faced initial skepticism of physicians because of fetal safety concerns. The perceived fetal risk has been found to be unwarranted and of late, the modality has attained acceptability. Its role in diagnosing fetal anomalies is well recognized and following its safety certification in pregnancy, it is finding increasing utilization during pregnancy and puerperium. However, the use of MRI in maternal emergency obstetric conditions is relatively limited as it is still evolving. In early gestation, ectopic implantation is one of the major life‑threatening conditions that are frequently encountered. Although ultrasound (USG) is the accepted mainstay modality, the diagnostic predicament persists in many cases. MRI has a role where USG is indeterminate, particularly in the extratubal ectopic pregnancy. Later in gestation, MRI can be a useful adjunct in placental disorders like previa, abruption, and adhesion. It is a good problem‑solving tool in adnexal masses such as ovarian torsion and degenerated fibroid, which have a higher incidence during pregnancy. Catastrophic conditions like uterine rupture can also be preoperatively and timely diagnosed. MRI has a definite role to play in postpartum and post‑abortion life‑threatening conditions, e.g., retained products of conception, and gestational trophoblastic disease, especially when USG is inconclusive or inadequate. -
International Standards for Symphysis-Fundal Height Based on BMJ: First Published As 10.1136/Bmj.I5662 on 7 November 2016
RESEARCH OPEN ACCESS International standards for symphysis-fundal height based on BMJ: first published as 10.1136/bmj.i5662 on 7 November 2016. Downloaded from serial measurements from the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project: prospective cohort study in eight countries Aris T Papageorghiou,1 Eric O Ohuma,1,2 Michael G Gravett,3,4 Jane Hirst,1 Mariangela F da Silveira,5,6 Ann Lambert,1 Maria Carvalho,7 Yasmin A Jaffer,8 Douglas G Altman,2 Julia A Noble,9 Enrico Bertino,10 Manorama Purwar,11 Ruyan Pang,12 Leila Cheikh Ismail,1 Cesar Victora,6 Zulfiqar A Bhutta,13 Stephen H Kennedy,1 José Villar,1 On behalf of the International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st) For numbered affiliations see ABSTRACT visible during examination. The best fitting curve was end of article. OBJECTIVE selected using second degree fractional polynomials Correspondence to: To create international symphysis-fundal height and further modelled in a multilevel framework to A Papageorghiou, Nuffield standards derived from pregnancies of healthy women account for the longitudinal design of the study. Department of Obstetrics & Gynaecology, University of with good maternal and perinatal outcomes. RESULTS Oxford, John Radcliffe Hospital, DESIGN Of 13 108 women screened in the first trimester, 4607 Headington, Oxford OX3 9DU, UK aris.papageorghiou@obs-gyn. Prospective longitudinal observational study. (35.1%) met the study entry criteria. Of the eligible ox.ac.uk SETTING women, 4321 (93.8%) had pregnancies without major Additional material is published Eight geographically diverse urban regions in Brazil, complications and delivered live singletons without online only. -
Prenatal and Preimplantation Genetic Diagnosis for Mps and Related Diseases
PRENATAL AND PREIMPLANTATION GENETIC DIAGNOSIS FOR MPS AND RELATED DISEASES Donna Bernstein, MS Amy Fisher, MS Joyce Fox, MD Families who are concerned about passing on genetic conditions to their children have several options. Two of those options are using prenatal diagnosis and preimplantation genetic diagnosis. Prenatal diagnosis is a method of testing a pregnancy to learn if it is affected with a genetic condition. Preimplantation genetic diagnosis, also called PGD, is a newer technology used to test a fertilized embryo before a pregnancy is established, utilizing in vitro fertilization (IVF). Both methods provide additional reproductive options to parents who are concerned about having a child with a genetic condition. There are two types of prenatal diagnosis; one is called amniocentesis, and the other is called CVS (chorionic villus sampling). Amniocentesis is usually performed between the fifteenth and eighteenth weeks of pregnancy. Amniocentesis involves inserting a fine needle into the uterus through the mother's abdomen and extracting a few tablespoons of amniotic fluid. Skin cells from the fetus are found in the amniotic fluid. These cells contain DNA, which can be tested to see if the fetus carries the same alterations in the genes (called mutations) that cause a genetic condition in an affected family member. If the specific mutation in the affected individual is unknown, it is possible to test the enzyme activity in the cells of the fetus. Although these methods are effective at determining whether a pregnancy is affected or not, they do not generally give information regarding the severity or the course of the condition. -
Proteomic Biomarkers of Intra-Amniotic Inflammation
0031-3998/07/6103-0318 PEDIATRIC RESEARCH Vol. 61, No. 3, 2007 Copyright © 2007 International Pediatric Research Foundation, Inc. Printed in U.S.A. Proteomic Biomarkers of Intra-amniotic Inflammation: Relationship with Funisitis and Early-onset Sepsis in the Premature Neonate CATALIN S. BUHIMSCHI, IRINA A. BUHIMSCHI, SONYA ABDEL-RAZEQ, VICTOR A. ROSENBERG, STEPHEN F. THUNG, GUOMAO ZHAO, ERICA WANG, AND VINEET BHANDARI Department of Obstetrics, Gynecology and Reproductive Sciences [C.S.B., I.A.B., S.A.-R., V.A.R., S.F.T., G.Z., E.W.], and Department of Pediatrics [V.B.], Division of Perinatal Medicine, Yale University School of Medicine, New Haven, CT 06520 ABSTRACT: Our goal was to determine the relationship between 4 vein inflammatory cytokine levels, but not maternal serum val- amniotic fluid (AF) proteomic biomarkers (human neutrophil de- ues, correlate with the presence and severity of the placental fensins 2 and 1, calgranulins C and A) characteristic of intra-amniotic histologic inflammation and umbilical cord vasculitis (7). inflammation, and funisitis and early-onset sepsis in premature neo- Funisitis is characterized by perivascular infiltrates of in- nates. The mass restricted (MR) score was generated from AF flammatory cells and is considered one of the strongest hall- obtained from women in preterm labor (n ϭ 123). The MR score marks of microbial invasion of the amniotic cavity and fetal ranged from 0–4 (none to all biomarkers present). Funisitis was graded histologically and interpreted in relation to the MR scores. inflammatory syndrome (8,9). While there is some debate with Neonates (n ϭ 97) were evaluated for early-onset sepsis. -
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Massive Subchorionic Haemorrhage: a Rare Case Report Associated with Secondary PPH Due to Uterine Artery Pseudoaneurysm
International Journal of Reproduction, Contraception, Obstetrics and Gynecology Arumaikannu J et al. Int J Reprod Contracept Obstet Gynecol. 2017 Oct;6(10):4723-4726 www.ijrcog.org pISSN 2320-1770 | eISSN 2320-1789 DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20174475 Case Report Massive subchorionic haemorrhage: a rare case report associated with secondary PPH due to uterine artery pseudoaneurysm J. Arumaikannu*, S. Usha Rani, T. S. Aarifa Thasleem Institute of Obstetrics and Gynecology, Egmore, Chennai, Tamil Nadu, India Received: 08 August 2017 Accepted: 04 September 2017 *Correspondence: Dr. J. Arumaikannu, E-mail: [email protected] Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Massive subchorionic hemorrhage is a rare but serious condition in pregnancy in which a large amount of blood, mainly maternal collects between the uterine wall and the chorionic membrane and may leak through the cervical canal. Although many associations have been reported, an underlying etiology has not been elucidated. Association of massive subchorionic hemorrhage with thrombophilias have been reported in few articles. We are reporting a case of massive subchorionic hemorrhage presented at 13 weeks of gestation associated with secondary post-partum hemorrhage due to uterine artery pseudoaneurysm. Keywords: Massive subchorionic haemorrhage, Secondary PPH, Uterine artery pseudoaneurysm INTRODUCTION hemorrhage in the second trimester may also compromise maternal health.2,3 During pregnancy, minor degrees of haemorrhage on the chorionic plate surface of the placenta are commonly A subchorionic hemorrhage can be considered large or identified on ultrasound assessment. -
Preparing for the Birth of Your Baby
Preparing for the birth of your baby The end of your pregnancy journey is in sight The last few weeks of pregnancy may feel the longest and are often the busiest. You might be eager to see your feet and sleep on your stomach again. You’re probably also tired of running to the bathroom in the wee hours of the night to relieve your bladder. Welcome to the end stage of your pregnancy, where time seems to slow down and the waiting seems never ending. Pass the time productively by getting as much done as you can before the big day arrives but also ensure that you get enough rest. Nesting When you are driven by the urge to do things like reorganising the cupboards, alphabetising the spice rack, pairing up all the stray socks that have lost their partners, defrosting the freezer, cleaning the bathroom’s tile grout with a toothbrush and getting rid of dust under the bed, this is part of a pre-labour ritual commonly known as nesting. In nature, expectant mothers prepare their ’nest’ for the soon-to-arrive baby; and the nesting instinct in humans can be as powerful as it is for animals. If and when the nesting instinct hits you, make the most of this productive phase. Here are some suggested things that you might want to tick off your list before labour and delivery: Restock your fridge As you prepare for birth, throw away any outdated items and shop for fresh ones. Stock up on key essentials like milk, yoghurt, cheese, juice, fruits and vegetables, fruit and meat you’ll want to have on hand once you’re home with your baby . -
Maternal Assessment 1
University of Babylon / College of Nursing University of Babylon College of Nursing MATERNAL ASSESSMENT 1 SUPERVISOR BY : - DR.AMEAN STUDEND NAME: - ZAINAB ALI HUSSEIN ROSSUL HAMZA ALYAA NEMIA The aim of maternal assessment 2 1- to identify the high risk of cases 2- to prevent and treat early complication 3- to ensure from contained risk assessment and provide on going to primary health care 4- educate the mother about physiology of pregnancy and labor and care newborn The procedures of the first visit 3 1- Demographic data ( age – occupation- LMP- EDD- P G A- type of labor – blood group + RH) 2- Family history 3- past history 4 -obstetric history 5 -mensterial history Signs of pregnancy 4 - Breast changes - Nausea & vomiting - Amenorrhea - Frequent urination - Fatigue & uterine enlargement - Line anigra - Melasma - Goodell signs - Hegar signs - Braxton contraction First Trimester 5 * (Subjective symptoms) - Amenorrhoea - Morning sickness - Frequent of micturation - Breast discomfort - Fatigue - breast changes Objective signs 6 - breast changes - abdominal enlargment - pelvic changes * ( THE TESTING FOR DIAGNOSIS OF PREGNANCCY IN FIRST TRIMESTER ( BHCG) AND ( U/S) 7 -gestational sac( 29-35) day of gestation - gastational age to determine by the detecting the following structures - cardiac activity in (6 week) and heart rate at (10 weeks) - embryo growth by 7 weeks Second trimester 8 General examination - Breast changes - Enlargment of lower abdomen - abdomenal examination :- included:- a-inspaction:-