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Gary M. Glazer, M.D. 2005 LUCAS ANNUAL REPORT on May 21

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Gary M. Glazer, M.D. 2005 LUCAS ANNUAL REPORT on May 21 Gary M. Glazer, M.D. Emma Pfeiffer Merner Professor in the Medical Sciences Professor and Chairman Department of Radiology 2005 Lucas annuaL RepoRt septembeR 20, 2005 On May 21, 2005 the Stanford University Department of Radiology celebrated one hundred years of making ra- diology history. The centennial celebration began with historical and scientific exhibits presented by the faculty. A symposium was held to explore the potential of biomedical imaging and targeted therapies to lead the way in making personalized medicine a reality. Looking back over the past century, we feel immense pride in the stunning achievements of our Department. These legacies include harnessing the power of the linear accelerator to treat cancer, developing a cure for Hodgkin’s disease, and advancing non-invasive imaging using x-ray and magnetic resonance methods to better understand the structure and function of living systems. Our second century began on a high note with the opening of the expansion of the Lucas Center for Imaging. Together with the original Lucas Center, completed in 1992, both buildings constitute one of the world’s largest centers for imaging located on a University campus. The expansion involved the addition of two underground stories: the approximately 20,000 square feet of new space more than doubled the size of the Lucas Center. The expansion houses faculty and equipment associated with the Radiological Sciences Laboratory and Radiology’s Molecular Imaging Program. Major new installations include a 7T whole body magnet, a cyclotron and associ- ated radiochemistry facilities, wet labs for biology and chemistry and a unique education center with the latest technology for fully interactive learning. These exceptional facilities have facilitated recruitments of key scien- tists representing a variety of disciplines. We are delighted that our current work is well recognized. Our investigations have graced the covers of three major scientific publications this year and our faculty are competing very effectively for federal funding. I am particularly proud that we have NIH-funded Centers for both MR Technology development and for in-vivo Cellular and Molecular Imaging. These Center grants are important because they support a core infrastructure as well as provide recognition for our excellence in these key areas. We intend to develop more national centers in the years ahead. I believe we now have the team in place at Stanford to create the quality of advances that our faculty created in the past century. Recognizing that today diseases are detected late in their natural history, we have a tremendous opportunity to improve human health through earlier diagnosis thereby enhancing therapy. Indeed some even dream that disease, once better understood, can be prevented by appropriate methods before it becomes macro- scopic or clinically evident. We could not ask for better supporters and partners as we begin our second century. 1201 Welch Road, Room P263 • Palo Alto, CA 94304 Telephone: 650.723.7863 • Fax: 650.723.7159 • E-Mail: [email protected] Acknowledgements With the 2005 LUCAS REPORT we celebrate and reflect on another year of remarkable achievements and gratefully acknowledge the continued support of all our sponsors and collaborators. Special Thanks to: The Richard M. Lucas Cancer Foundation and The National Institutes of Health NCRR P41 RR09784 and NCI P50 CA114747 And many thanks to Kevin Murphy for the many hours of hard work and dedication in preparing this Annual Report for Publication. Lucas Annual Report 2005 Lucas Annual Report 2005 Table of Contents Chairman’s Letter .....................................................................................................................................................................i Acknowledgements .................................................................................................................................................................v Table of Contents ..................................................................................................................................................................vii Stanford Radiology 2005 ........................................................................................................................................................1 Collaborators ...........................................................................................................................................................................2 Lucas Annual Report ...............................................................................................................................................................3 Overview: Radiological Science Laboratory and Center for Advanced MR Technology ......................................................5 Overview: Molecular Imaging Program at Stanford ..............................................................................................................7 Overview: Strategic Research Development ..........................................................................................................................9 Sponsored Research ..............................................................................................................................................................10 2005 Group Photo of the Radiology Research Faculty, Staff and Students .........................................................................12 Radiology Scientific Research Personnel .............................................................................................................................13 Awards and Honors ...............................................................................................................................................................15 Group Summaries .................................................................................................................................................................17 RSL Group Updates .......................................................................................................................................................19 Functional Imaging - Technology Development ......................................................................................................19 Funtional “Microvascular” Neuroimaging .............................................................................................................20 Magnetic Resonance Spectroscopy ..........................................................................................................................20 Interventional and Open MRI ..................................................................................................................................21 Cardiovascular Imaging ..........................................................................................................................................21 X-ray Guidance of Interventional Procedures .........................................................................................................22 Inverse Geometry CT and Conventionl CT ..............................................................................................................22 Imaging Analysis ......................................................................................................................................................23 Statistical Modeling and Outcomes Analysis ...........................................................................................................23 Proteomics, Biomarkers, and Nonoparticle Platforms for Imaging and Therapeutics ...........................................24 MIPS Group Updates .....................................................................................................................................................25 Multimodality Molecular Imaging ...........................................................................................................................25 Molecular Imaging Instrumentation Lab .................................................................................................................25 Cellular and Molecular Imaging Lab ......................................................................................................................26 Molecular Imaging Probe Laboratory .....................................................................................................................26 Molecular Imaging of Musculoskeletal Illnesses .....................................................................................................27 Nuclear Medicine Research Lab ..............................................................................................................................27 Cardiovascular Molecular Imaging ........................................................................................................................27 Education and Research Facilities ........................................................................................................................................29 Postgraduate Education ..................................................................................................................................................31 NCI Training Program ....................................................................................................................................................32 MIPS Training Program .................................................................................................................................................33
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