FORMER GRADUATE STUDENTS Name Degree and Thesis Title Postdoc Institution Current Position and Location Contact Information Year Dr. Lee D. Arnold 1987, Ph.D. Serine β-Lactones in Syntheses of Amino Acids None President & CEO of Discovery Elucidations [email protected] Dr. Hanaa Assil 1989, M.Sc. Solid Supports for Azodicarboxylates in Mitsunobu Reactions n/a Unknown Unknown and Synthesis of Amino Acids Dr. Karine Auclair 1999, Ph.D. Biosynthetic Studies on the Polyketide Lovastatin: Enzyme- Prof. P. Ortiz De Montellano, Department Assoc. Professor, Department of Chemistry, McGill University, [email protected] Catalyzed Diels-Alder Reactions of Pharmaceutical Chemistry, University of Montreal, Que., Canada California at San Francisco, USA Dr. Jennifer Blunston (nee Caplan) 2001, Ph.D. Diaminopimelic Acid Analogues as Inhibitors of Enzymes Prof. D. Waisman, Departments of Stay-at-home mom, raising son Rhys. Previously Jennifer [email protected] Involved in Bacterial Lysine Biosynthesis Biochemistry and Oncology, University of Blunston was Assistant Professor of Chemistry, St. Mary's Calgary, Canada University College, Calgary, AB, Canada Dr. Marc Boudreau 2007, Ph.D. Nucleoside Dicarboxylates as Mimics of Diphosphates and Prof. Hagan Bayley, Oxford University Postdoc with Professor Shahriar Mobashery, University of Notre [email protected] Disulfide Bond Replacement in Pediocin PA1 Dame Dr. Doug Burr 2006, Ph.D. Studies of the in vitro Activity of Lovastatin Nonaketide Prof. David Sherman, Dept. Medicinal Research scientist at Perkin Elmer, Boston, Massachusetts [email protected] Synthase Chemistry, University of Michigan, Ann Arbor, MI Dr. Hengmiao (Henry) Cheng 1992, Ph.D. Mechanism and Inhibition of Peptidylglycine α-Hydroxlating Prof. E.J. Corey, Department of Chemistry, Senior Research Investigator, Pfizer Global Research and [email protected] Monooxygenase Harvard University Development, Pfizer Inc., Groton, CT, USA Dr. Jamie Cote 2007, Ph.D. Alcohol Dehydrognase Catalyzed Diels Alder Reactions and Prof. Michel Rohmer, University of Lab Manager, Hunter Group, Aurora, Ontario. [email protected] Synthetic Studies Toward Putative Intermediates in the Post- Strasbourg, France PKS Transformations of Dihydromonacolin L Dr. Darren Derksen 2007, Ph.D. Synthesis and Biological Evaluation of Bacteriocin Analogs Prof. Ian Paterson, Department of Assistant Professor, Chemistry Dept, St. Francis Xavier [email protected] and the Analgesic Peptide Crotalphine Chemistry, Cambridge University University Mr. John Drover 1986, M.Sc. The Synthesis of α-Amino Acids using the Regiospecific n/a Research Technician, Agriculture and Agri-Food Canada, Pacific [email protected] Ring Opening of α-Amino-β-Lactones and the Preparation of Agri-Food Research Centre, Summerland, BC, Canada some Thalidomide Analogs Mr. Mitchel Flegel 2007, M.Sc. Photodecarboxylation of Amino Acids and Synthesis of DAP n/a Intellectual Property Coordinator, Alberta Research Council, [email protected] Analogs to be Tested Against Enzymes Involved in Plant Edmonton, AB Lysine Biosynthesis Dr. Jiasheng Fu 2000, Ph.D. Investigation of Stereoselection by the Mitsunobu Reaction Prof. M. Greenberg, Department of Scientist, Amgen, Thousand Oaks, California, USA [email protected] and Modification of the Hendrickson Reaction Chemistry, Colorado State University, USA Dr. Yong Gao 1998, Ph.D. Synthesis of Diaminopimelic Acid (DAP) and Analogues; Prof. R. Rando, Department of Biological Assoc. Professor, Department of Chemistry and Biochemistry, [email protected] Mechanistic Studies on DAP Aminotransferase, Epimerase Chemistry and Molecular Pharmacology, Southern Illinois University at Carbondale, Carbonadale, IL, and Dehydrogenase Harvard Medical School, USA USA Dr. Sylvie Garneau-Tsodikova 2003, Ph.D. New Antimicrobial Agents Acting on Bacterial Cell Walls Prof. C. Walsh, Department of Biological Assist. Prof., School of Pharmacy, University of Michigan, Ann [email protected] Chemistry and Molecular Pharmacology, Arbor, Michigan Harvard Medical School, USA Dr. Makarand Gore 1987, Ph.D. Studies on Stereocontrolled Syntheses of α-Hydroxy, α-N- Prof. S. Gould, Department of Chemistry, Dierctor ChemicalSciences, Hewlett-Packard Company, Fort [email protected] Hydroxyamino, α-Oxyamino and α-Hydrazino Acids for Oregon State University, USA Collins CO, USA Inhibition of Enzymes Dr. Paul Harrison 1987, Ph.D. Studies on the Biosynthesis and Mechanism of Action of Prof. D. Cane, Department of Chemistry, Professor, Department of Chemistry, McMaster University, [email protected] Polyene Antibiotics Brown Univertsity Hamilton, ON, Canada Ms. Yanting Huang 1997, M.Sc. Design and Synthesis of Potential Inhibitors of HAV-3C n/a Research Scientist, Medicinal Chemistry Division, Bristol Myers [email protected] Proteinase Squibb, Princeton, NJ, USA Dr. James Kapron 1993, Ph.D. Synthesis of Cysteine Derivatives and Hydrazinoserine Prof. M. Mutter, University of Lausanne, Scientist, Bruker, Canada. [email protected] Switzerland Dr. Karen Kawulka 2003, Ph.D. Investigations of Bacteriocins from Carnobacterium Prof. J. Vederas, University of Alberta Chemical Professional Consultant, Edmonton, Alberta, Canada. [email protected] piscicola, Brocothrix campestris and Bacillus subtilis Dr. Janice Kelland 1986, Ph.D. Studies on Inhibition of Diaminopimelic Acid Metabolism Prof. D. Williams. Department of Patent Agent, Moffat & Company, Ottawa, Ontario. [email protected] and Fast Atom Bombardment Mass Spectra of Nucleosides Chemistry, Cambridge University UK and Nucleotides Dr. Manjinder Lall 1999, Ph.D. Hepatitis A Virus 3C Proteinase: Inhibitor Design, Synthesis Prof. D. Boger, Department of Chemistry, Senior Scientist, Chemistry, Pfizer Global Research & [email protected] and Testing Scripps Research Institute, USA Development, Groton CT, USA - 2 - Dr. Patricia Lane-Bell 1991, Ph.D. Synthesis of Diaminopimelic Acid (DAP) and Analogs; Prof. S. Jensen, Department of Biology, Home Address Calgary, Alberta [email protected] Inhibition Studies on DAP Dehydrogenase and DAP University of Alberta, Canada Epimerase Dr. Jesse Li Investigation of Highly-Reducing Polyketide Synthase Prof. Craig Townsend, Department of [email protected] Enzymes that Produce the Fungal Polyketides Lovastatin, Chemistry, Johns Hopkins University, Fumonisin B1, and Hypothemycin Baltimore, Maryland, USA. Dr. Zhe Li 1992, Ph.D. Biosynthetic Studies of the Polyketides, Fungichromin and Prof. G. Kenyon, Department of Associate Professor, Institute Neurodegenerative Diseases, [email protected] Dehydrocurvularin: Incorporation of Advanced Precursors Pharmaceutical Chemistry, University of University of California, San Francisco, California. USA California at San Francisco, USA Dr. Hongqiang (Patrick) Liu 2010, Ph.D. Chemical synthesis and biological evaluation of naturally University of Toronto, Toronto, Ontario. Postdoc with Professor Mark Lautens, Chemistry Department, [email protected] occurring cyclic peptides and their analogues: Lacticin 3147 University of Toronto A2 and Neopetrosiamides Dr. Yaoquan (Gary) Liu 1996, Ph.D. Biosynthetic Studies on Dehydrocurvularin, and Modification Prof. D. Santi, Department of Associate Director, Evolva Inc. Palo Alto, California, USA [email protected] of the Swern Oxidation Pharmaceutical Chemistry, University of California at San Francisco, USA Dr. Nathaniel Martin 2003, Ph.D. Pseudoxazolines as Hepatitis A Virus 3C Proteinase Inhibitors Prof. M. Marletta, Department of Assistant Professor, Department of Medicinal Chemistry and [email protected] and Bacterially Derived Antimicrobial Peptides Chemistry, University of California at Chemical Biology, University of Utrecht, Utrecht, Netherlands Berkeley, USA Dr. Leah Martin-Visscher 2010, Ph.D. Examining the structure, function and mode of action of n/a Assistant Professor of Chemistry, The King's University College, [email protected] bacteriocins from lactic acid bacteria Edmonton, AB (starting July 2011) Mr. Aubrey Mendonca 1989, M.Sc. Development of a Chiral Aminating Reagent and Amination n/a President, ChemRoutes Corporation, Edmonton, AB, Canada [email protected] Studies on Chiral and Achiral Molecules Miyyapuram Venugopal Rao 2010 Synthesis and Investigation of Viral Cysteine Protease n/a Faculty of Pharmacy, University of Alberta [email protected] (Venu) Inhibitors and Biosynthetic Studies on Subtilosin A Dr. Richard Moore 1984, Ph.D. I. The Synthesis of Serine Stereospecifically Labelled at C-3 Prof. C. Walsh, Department of Chemistry, Software developer, Casper, Wyoming, USA. [email protected] II. The Study of Biosynthesis Using Stable Isotope NMR Massachusetts Institute of Technology USA Techniques Dr. Kelly O'Callaghan 1997, Ph.D. Phenylbutenoic Acids as Inhibitors of Peptide Amidation n/a Home address Calgary, Alberta, previously Assist. Professor of [email protected] Chemistry, Red Deer College, Red Deer, Alberta Dr. Sunil Pansare 1989, Ph.D. New Methods for Synthesis of β-Substituted α-Amino Acid Prof. S. Denmark, Department of Associate Professor, Department of Chemistry, Memorial [email protected] Derivatives Chemistry, University of Illinois, USA University of Newfoundland, St. John's, NF, Canada Dr. Vijaya Pattabiraman 2007, Ph.D. Chemical Synthesis of Lantibiotics and Their Analogues Prof. Jeffrey Bode, Department of Prof. Jeffrey Bode, Department of Chemistry, ETH Zürich [email protected] Chemistry, University of Pennsylvania, (Swiss