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Descargar Descargar Comisión Editorial Ana Ruth Vílchez Rodriguez. Directora. Instituto Tecnológico de Costa Rica Juan Antonio Aguilar Garib Facultad de Ingeniería Mecánica y Eléctrica Universidad Autónoma de Nuevo León. La Editorial Tecnológica de Costa Rica es una México dependencia especializada del Instituto Tecnológico de Carlos Andrés Arredondo Orozco Costa Rica. Desde su creación, en 1978, se ha dedicado a Facultad de Ingenierías la edición y publicación de obras en ciencia y tecnología. Universidad de Medellín. Colombia Las obras que se han editado abarcan distintos ámbitos Lars Köhler respondiendo a la orientación general de la Institución. Experimenteller Botanischer Garten Georg-August-Universität Göttingen. Alemania Hasta el momento se han editado obras que abarcan distintos campos del conocimiento científico-tecnológico Jorge Solano Jiménez Instituto Costarricense del Cemento y han constituido aportes para los diferentes sectores de y del Concreto la comunidad nacional e internacional. Edición técnica La principal motivación de la Editorial es recoger Alexa Ramírez Vega y difundir los conocimientos relevantes en ciencia y Revisión filológica tecnología, llevándolos a los sectores de la comunidad Esperanza Buitrago Poveda que los requieren. Diseño gráfico Felipe Abarca Fedullo La revista Tecnología en Marcha es publicada por la Editorial Tecnológica de Costa Rica, con periodicidad Diagramación Asesoría en Ediciones gráficas trimestral. Su principal temática es la difusión de resultados de investigación en áreas de Ingeniería. El contenido de Diseño de cubierta la revista está dirigido a investigadores, especialistas, Felipe Abarca Fedullo docentes y estudiantes universitarios de todo el mundo. Imagen de cubierta M.Sc. Andrea Ulloa Fernández Datos de catalogación en publicación Tecnología en Marcha / Editorial Tecnológica de Costa Rica. - Vol. 32. Especial setiembre Publicación y directorio en catálogos (2019) –Cartago: la Editorial, 2019 – Trimestral ISSN-E 2215-3241 1. Ciencia y TecnologÍa – Publicaciones periódicas CDD:600 www.latindex.unam.mx http://www.scielo.org/ dialnet.unirioja.es Apdo 159-7050 Cartago, Costa Rica Tel.:(506) 2550-2297, 2550-2618 Correo electrónico: [email protected] Web: editorial.tec.ac.cr http://revistas.tec.ac.cr/tec_marcha http://www.doaj.org/ https://redib.org Revista trimestral. Especial 2019. 25 Aniversario del Centro de Investigación en Biotecnología ISSN 0379-3982 / ISSN-E 2215-3241 Contenido Presentación ................................................................................................................................................. 3 Proceso Visionario hacia el Desarrollo Biotecnológico Visionary Process towards Biotechnological Development Elizabeth Arnáez-Serrano, Ileana Moreira-González, Silvana Alvarenga-Venutolo, Ana Abdelnour-Esquivel, Dora Flores-Mora, Miguel Rojas-Chaves ........................................................... 6 Investigaciones en plantas con potencial bioactivo Investigations on plants with bioactive potential Catalina Rosales-López, Elizabeth Arnáez-Serrano, Ileana Moreira-González, Giovanni Garro-Monge, Ana Laura Agüero-Hernández, Karol Jiménez-Quesada, Ana Abdelnour-Esquivel, Laura Calvo-Castro. ............................................................................................................................... 12 Investigaciones en Cultivos Frutícolas No Tradicionales en el Centro de Investigación en Biotecnología del Instituto Tecnológico de Costa Rica Research in No Traditional Fruit Crops at the Biotechnology Research Center of Costa Rica Institute of Technology Alexander Schmidt-Durán, Carlos Alvarado-Ulloa, Randall Chacón-Cerdas, Dora Flores-Mora ............... 22 Publicación y directorio en catálogos Optimización de un protocolo de cultivo in vitro de embriones de Coyol (Acrocomia aculeata) Optimization of an in vitro culture protocol of Coyol embryos (Acrocomia aculeata) Katherine Sánchez-Zúñiga, Elizabeth Arnáez-Serrano, Ileana Moreira-González, Guillermo Vargas-Hernández .................................................................................................................. 30 Contribuciones al Desarrollo Forestal de Costa Rica Contributions to Forest Development of Costa Rica Elizabeth Arnáez-Serrano, Ileana Moreira-González .................................................................................... 36 Los bioprocesos en la biotecnología: uso de biorreactores para la producción y el escalamiento de productos de interés comercial Bioprocesses in biotechnology: use of bioreactors for the production and scaling of products of commercial interest Catalina Rosales-López ......................................................................................................................... 41 Tecnología en Marcha, Vol. 32 Especial. Setiembre 2019 2 25 Aniversario del Centro de Investigación en Biotecnología Implementación de las técnicas de RMN y cristalografía de macromoléculas para la caracterización estructural de proteínas de interés biomédico Implementation of NMR and macromolecular crystallography techniques for structural characterization of proteins of biomedical interest Silvia Arce-Solano, Erick Hernández-Carvajal ......................................................................................... 47 Cultivo Celular e Ingeniería de Tejidos: Aplicaciones en Biomedicina Cell Culture and Tissue Engineering: Biomedical Applications Johan Morales-Sánchez, Andrea Ulloa-Fernández, Silvia Castro-Piedra, Carolina Centeno-Cerdas, Laura A. Calvo-Castro ............................................................................................................................................... 56 Biotecnología para el estudio de enfermedades neuropsiquiátricas y la búsqueda de nuevos tratamientos: caso de las neuregulinas Biotechnology for the study of neuropsychiatric diseases and the search for new treatments: case of neuregulins María Clara Soto-Bernardini ........................................................................................................................ 66 Proyectos interuniversitarios y multidisciplinarios relacionados con el patógeno zoonótico Brucella abortus realizados en el CIB Interuniversity and multidisciplinary research projects about the zoonotic pathogen Brucella abortus developed in the CIB Olga Rivas-Solano ....................................................................................................................................... 77 Biotecnología microalgal en Costa Rica: Oportunidades de negocio para el sector productivo nacional Microalgal biotechnology in Costa Rica: Business opportunities to the national productive sector Fabián Villalta-Romero, Francinie Murillo-Vega, Bernal Martínez-Gutiérrez, Johnny Valverde-Cerdas, Andrés Sánchez-Kopper, Maritza Guerrero-Barrantes ............................................................................................ 85 Helicobacter pylori en Costa Rica, más de una década de investigaciones Helicobacter pylori in Costa Rica, more than a decade of research Virginia Montero-Campos ........................................................................................................................... 94 Proyectos relacionados con diversidad, ecología, desplazamiento, virulencia y potencial biotecnológico de cepas de Listeria spp. aisladas en Costa Rica a partir de muestras alimentarias, clínicas y ambientales Research projects about diversity, ecology, movement, virulence and biotechnological potential of Listeria spp. isolated in Costa Rica from food, clinic and environmental samples Kattia Núñez-Montero, Rossy Guillén-Watson, Olga Rivas-Solano, Johnny Peraza-Moraga ................... 104 Los insectos y la biotecnología: avispas sociales como fuente de nuevos compuestos antibióticos Insects and biotechnology: social wasps as a source for novel antibiotic compounds Laura Chavarría-Pizarro ............................................................................................................................. 114 Laboratorio de Biocontrol: Investigación vinculada con la producción agrícola Biocontrol Laboratory: Research linked to agricultural production William Rivera-Méndez, Jaime Brenes-Madriz, Claudia Zúñiga-Vega ....................................................... 121 Tecnología en Marcha, Vol. 32 Especial. Setiembre 2019 25 Aniversario del Centro de Investigación en Biotecnología 3 Presentación Miguel Rojas-Chaves1, Mauricio Chicas-Romero2, Laura A. Calvo-Castro3 El Centro de Investigación en Biotecnología (CIB), adscrito a la Escuela de Biología del Instituto Tecnológico de Costa Rica (TEC), se localiza en la zona este del Campus Central del TEC, en el Cantón Central de la provincia de Cartago, Costa Rica. Actualmente cuenta con 14 laboratorios especializados en tres áreas generales de Biotecnología (cuadro 1), un campo experimental frutícola, un invernadero y dos estanques para cultivo de microalgas a gran escala (20.000 L), ocupando una superficie de 15 mil metros cuadrados (figura 1). Figura 1. Fotografía área del Centro de Investigación en Biotecnología. Detrás del edificio principal se encuentra la zona de microalgas y a la derecha el campo frutícola. 1 Microbiólogo. Centro de Investigación en Biotecnología, Escuela de Biología, Insti- tuto Tecnológico de Costa Rica. Costa Rica. Correo electrónico: [email protected]. https://orcid.org/0000-0002-4770-5003 2 Ingeniero en Biotecnología. Centro de Investigación en Biotecnología, Escuela de Biología, Instituto Tecnológico de Costa Rica. Costa Rica.
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