August 2011 In this issue: Molecular Diagnostics CC Teen Retreat and Sibling Day Heart valve exhibit Clinical Center

CC chosen as 2011 Works, Inc. Employer of the Year The Clinical Center was chosen as the 2011 Employer of the Year by Maryland Works, Inc., for its pilot NIH- Project SEARCH program. Maryland Works, Inc., is a statewide member- ship association that advocates for increasing employment and business ownership opportunities for people with disabilities or other barriers to employment. The NIH-Project SEARCH program graduated 12 young adults with disabilities from a 30-week unpaid internship at the CC in June. Project SEARCH works with and businesses in the United States, the United Kingdom, and Australia to provide opportunities for young adults Clinical Center Director Dr. John I. Gallin (center) connected with Dr. Seunghye Han (left), a clinical fellow in the Critical Care Department; and Dr. Henry Masur, Critical Care Medicine Department chief, with disabilities to learn employability at the reception for new clinical fellows hosted by the OCRTME on July 27. skills and gain work experience. “The success of this program is New NIH fellows receive warm reception both in the tangible work these indi- viduals have delivered and in the im- More than 70 clinical fellows were invited to welcome newcomers to the NIH team. pact they have had on the culture of to network with graduate medical educa- “Individuals are coming to the NIH the ,” said Denise Ford, chief tion training program directors, other NIH because they know that the value added of CC Hospitality Services, who led staff, institute and center scientifi c and to their training is in the area of research the pilot program. “They have opened clinical directors, and NIH leadership at a training and research methodology,” Lem- people’s minds to the possibility and reception in the Clinical Center on July 27. bo said. “They have opportunities to have benefi t of employment of people with NIH attracts diverse talent from medical support in conducting their own research disabilities.” schools and academic institutions across projects, and they have the ability then to The CC partnered with The Ivy- the United States, offering the opportu- have a portfolio to take with them, should mount School in Rockville, and SEEC, nity to train at the CC’s 240-bed facility, they decide to leave the NIH, that allows a Montgomery County Adult Service the world’s largest hospital dedicated to them to be highly competitive relative to Provider, to welcome the interns clinical research. NIH clinical fellows col- academic positions.” to various roles in 13 departments. laborate with world-renowned physicians Dr. Jacqueline Mays, a new clinical fel- Eight of the 12 interns were offered to conduct cutting-edge investigational low at the National Institute for Dental and permanent employment upon gradu- protocols. Eighteen medical specialty or Craniofacial Research who will be provid- ation. The NIH plans to continue this subspecialty training programs accredited ing care to patients in the CC, attended partnership with a 2011-2012 class of by the Accreditation Council for Graduate the reception and said it was a great 10 interns at nine NIH institutes and Medical Education are available on cam- opportunity to talk with senior fellows, as centers. pus, as well as numerous one-of-a-kind well as NIH leadership. Ford accepted the 2011 Employer translational medicine fellowship training “Being a clinical fellow is brand new to of the Year award on behalf of the CC programs within the 27 NIH institutes and me,” said Mays. “I am just sort of getting at the Maryland Works, Inc., Fourth centers. my feet wet and fi guring out how the Annual Employment Awards Lun- Dr. Robert Lembo, executive director wide world of clinical research works.” cheon on June 22 at The Westin in of graduate medical education in the CC For more information on graduate Lithicum Heights. The awards honor Offi ce of Clinical Research Training and medical education at NIH, visit the OCRT- individuals with a disability who have Medical Education, said the reception aims ME website, clincialcenter.nih.gov/training. continued on page 3 Patients rock out with U2 and NIH Director Dr. Francis Collins Three young Clinical Center patients rocked out with NIH Director Dr. Francis S. Collins at the U2 concert in Baltimore on June 22. U2 guitarist and vocalist David Howell Evans, known better as The Edge, invited the group on stage before the concert for a few practice guitar licks and photo ops. The rock star had visited Collins last Octo- ber to talk about cancer research. When the U2360° tour came to the area, the NIH director, himself an avid guitarist, invited patients Lauren Weller, 26; Nachiketa Bhatnagar, 17; and An- drew Windland, 12, to the concert. “The whole show was about more than just the music,” said Weller. “You could tell they cared about important issues. It was very personal.” Indeed, The Edge has a personal connection to health issues—he sits on the Angiogenesis Foundation board, and his daughter, Sian, is a cancer survivor. The NIH group spent about an hour pre-con- cert with The Edge, chatting and generally just hanging out. He also hand-delivered souvenir On stage with The Edge (fourth, from right) before the U2 concert are (from left) Dr. William Li sunglasses from U2 lead singer Bono. of the Angiogenesis Foundation; CC patients Lauren Weller, Andrew Windland, and Nachiketa “It was pretty cool,” concluded Bhatnagar. Bhatnagar accompanied by family members; and Dr. Francis S. Collins, NIH director. CC Nutrition Department’s 19th class of dietetic interns graduate The Clinical Center Nutri- tion Department celebrated the graduation of the 19th dietetic internship class on July 1. Graduates, their families and friends, and Nutrition Department staff gathered for a celebratory luncheon and ceremony to honor the achievement of the four graduates—Emily Brown, Katrina Butner, Emily Cook, and Valerie Darcey. LCDR Merel Kozlosky, program director, com- mended the interns on their accomplishments throughout the 45-week program. “Our four interns this year are so Nutrition Department dietitians helped to honor the graduates including (from left) CAPT Madeline Michael, chief of very accomplished, and I Clinical Nutrition Services; internship graduates Valerie Darcey, Emily Cook, Katrina Butner, and Emily Brown; LCDR know they will go far in their Merel Kozlosky, dietetic internship program director; and Dr. Kirsten Zambell, clinical research dietitian. careers,” she said.

Clinical Center News Nicole Martino, editor Published monthly for Clinical Center employees online: by the Offi ce of Communications, Patient Recruit- Clinical Center News ment, and Public Liaison, Sara Byars, chief. National Institutes of Health www.cc.nih.gov/about/news/newsletter.html Department of Health and Human Services News, article ideas, calendar events, letters, and Building 10, 10 Center Drive, Room 12C440 photos are welcome. Bethesda, MD 20892-1504 Submissions may be edited. Tel: 301-496-6787 Fax: 301-480-2984

2 Clinical Center news August 2011 Sibling Day acknowledges important role of support system Brothers and sisters share a certain con- CC Recreation Therapy Section chief nection and protective spirit that bonds Donna Gregory, Wiener, and pediatric on- them in a unique way. When one is suf- cology fellow Dr. Sima Zadeh led therapeu- fering from a serious illness, the others tic events in the afternoon where siblings also suffer from feelings of helplessness could share their fears and hopes about and from the challenge to the fam- their brothers and sisters’ conditions and ily unit. The NIH realizes that pediatric treatments, and what the experience is patient siblings are an important popula- like for them. CC art therapist Tosha Davis tion, both in the care of a sick child and helped the children make worry dolls out in their own right, and has devoted a of fabric and yarn. day to celebrating and supporting these Sibling Day concluded with an awards “super sibs.” ceremony at The Inn where each sibling “It’s been very clear over the years was presented with a certifi cate commem- that the pain the brother or sister experi- orating their participation and role as a ences is pretty invisible compared to “Super Sib, Super Star.” Parents, patients, what they witness going on in the fam- and staff gathered to applaud this vital role ily, which is why we have created one in the family system. day a year where siblings can be recog- Arthur Knopfmacher, who has attended nized for their role in the family,” said Sibling Day three times over the last four Dr. Lori Wiener, head of the National years, said, “It’s really fun. I suggest if CC art therapist Tosha Davis (second, from left) helped some of the super siblings make worry Cancer Institute’s Pediatric Psychosocial people are sick, come here. This building dolls out of fabric and yarn. Support and Research Program and a is fun.” founder of The Children’s Inn at NIH. Sibling Day is a collaboration be- tween Wiener’s program, the Clinical Center Rehabilitation Medicine Depart- ment Recreation Therapy Section, and The Children’s Inn. These groups support siblings of pediatric patients year-round through on-going programs and events but unite for one day that is focused just on the siblings. The annual event started off on July 19 at The Inn with some icebreakers. The kids answered questions like “What do you want to be when you grow up?” and “If you could have any super power, which would you pick?” More than one child said that he or she would choose the power to cure. “It’s kind of a hard thing to go Supervisory health technologist Belinda Avila (right) lead the siblings in a tour of the operating room. through for her, and it’s kind of a hard thing to go through for us,” said Eric Downey, 18, from Massachusetts of one CC chosen as 2011 Employer of the Year of his sister’s illness. continued from page 1 The 13 Sibling Day participants visited achieved career goals; NIH Medical Arts where they learned workforce professionals about patient photography and took who have made a signifi - photos in front of a green screen—then cant contribution to the printed as them posing with the Holly- employment of people wood sign or Justin Beiber, among other with disabilities; and tran- options. They dressed as medical tech- sition teachers, employers, nologists and learned about laboratory public policy champions, tests in the CC Department of Labora- and community service tory Medicine. providers who advocate Each was given the chance to try out and expand skills training Denise Ford (second, from right) accepted the award from Su- the mock scanner to feel what it is like and employment opportu- zanne Page (left), assistant state superintendent in the Maryland for their sibling to get an MRI and suited nities for people with dis- Division of Rehabilitation Services; Pamela Kumar, chair of the up for a trip to the operating room to abilities or other barriers Maryland Works, Inc., board of directors; and Bob Hofmann, learn about procedures and work on a to employment. Maryland Works, Inc., president and CEO. dummy patient.

August 2011 Clinical Center news 3 Registration for pharmacology course open The Principles of Clinical Pharmacology course, sponsored by the Clinical Center, will begin in Lipsett Amphitheater on September 1. The course will be held Thursdays from 6:30 pm to approxi- mately 7:45 pm and will run through April 26, 2012. The registration deadline is August 31. “Many medical schools don’t offer formal courses in clinical pharmacology,” said Dr. John I. Gallin, CC director. “This course covers what researchers need to know concerning the clinical pharmaco- logic aspects of drug development and use.” At the ribbon cutting ceremony for the new “Innovation & Invention: NIH and Prosthetic Heart Valves” Topics such as pharmacokinetics, exhibit July 11 were (left to right) Dr. Michael Gottesman, director, Offi ce of Intramural Research; Dr. drug metabolism and transport, assess- Eugene Braunwald, professor, (former NHLBI cardiology chief and clinical di- ment of drug effects, drug therapy in rector); Dr. Susan B. Shurin, acting director, NHLBI; Walter Lingenfelter, former CC patient; Dr. Theodor special populations, and drug discovery Kolobow, former physician, Pulmonary and Critical Care Medicine Branch, NHLBI; Dr. Keith Horvath, chief, Cardiothoracic Surgery Research Program, NHLBI, and chief of cardiothoracic surgery, NIH Heart and development are taught. “We have Center, Suburban Hospital; and Dr. Robert Martensen, director, Offi ce of NIH History. assembled an outstanding faculty for this course, drawing from the scientifi c staff at the NIH, the FDA, the pharma- Prosthetic heart valve exhibit opens ceutical industry, and many prestigious The past and present united July 11 at when Lingenfelter received a second academic institutions in the United the opening of the new “Innovation heart surgery that he said he hopes States,” said course director Dr. Juan & Invention: NIH and Prosthetic Heart keeps him going another 50 years. Lertora, CC director of clinical pharma- Valves” exhibit in the Clinical Center’s “They told my parents that if I cology, and member of the Offi ce of south lobby. made it to age 18 that would be Clinical Research Training and Medical Current and former researchers, good, because all of this was pretty Education. patients, leadership, and staff gathered much brand new. When they went Since the course was fi rst offered to tell their stories of early open-heart in, I was a bit more messed up than 14 years ago, it has expanded beyond surgery and amazing survivals, and how they had thought,” Lingenfelter said. the CC to include a number of off-site NIH played a critical role in revolutioniz- “Of course, they never told me how partners. Last year 757 students from ing cardiac care. they felt. But I know how I felt, and 23 long-distance sites registered for the “This exhibit describes the birth of a I wasn’t going to celebrate yet. I was course, in addition to the 444 enrollees fi eld that has transformed medical prac- going to do the best that I could and at the NIH. This was a record number of tice throughout the world and people’s do what they tell me. And now I’m 63, registrants. lives,” said Dr. Susan B. Shurin, acting and I’m still moving.” “We have been very pleased with the director of the National Heart, Lung, Future Offi ce on NIH History proj- great interest generated by this course,” and Blood Institute. “This is built upon a ects include a documentary fi lm on added Dr. Frederick P. Ognibene, deputy strong bedrock of biomedical science ... prosthetic heart valves and a web- director for educational affairs and stra- bolstered by spectacular engineering.” based version of the exhibit. tegic partnerships at the CC and director The exhibit was produced by the Of- “Most people think of the museum of the OCRTME. fi ce of NIH History’s DeWitt Stetten, Jr., as a bone yard for old technologies. Registration is open to all interested Museum of Medical Research, in collab- Our true mission is to be a reliquary individuals without charge, unless the oration with the FDA’s Offi ce of History. for honored traditions and memories. course is being taken for graduate For many visitors, the exhibit will We think of this as social and cultural credit. This course may be taken for serve as a lesson in history. For Walter T. history, looking at the community graduate credit through The Foundation (formerly “Little Tommy”) Lingenfelter, of NIH,” said Hank Grasso, exhibi- for Advanced Education in the Sciences, it is a walk down memory lane. In 1958, tion content developer at the Dewitt Inc. (FAES) as PHAR 500 I and PHAR 500 when Lingenfelter was 10, NIH surgeon Stetten, Jr., Museum of Medical Re- II. Contact the FAES directly at 301-496- Dr. Andrew “Glenn” Morrow repaired search. “The things that we fi nd fasci- 7976 before August 20. two damaged heart valves and sewed nating are the things that are never in For more information, including up a partition in Lingenfelter’s heart. the records ... the interesting happen- online registration, visit clinicalcenter.nih. Lingenfelter’s parents were told that stances, the surprises, the disappoint- gov/training/training/principles.html or he might live to age 18. Nevertheless, ments. Those kinds of things fi ll in the call 301-496-9425. the repairs to his heart held until 2006, gaps and tell the real story.”

4 Clinical Center news August 2011 Molecular diagnostics, unlocking DNA code to detect disease

By Ellen Crown States, such as malaria. PCR also makes it possible to crack the Rapidly diagnosing disease is an enor- tough cases, such as non-cultivatable or mous advantage offered by the Molecu- slow-growing microorganisms. lar Diagnostics Service at the Clinical Fahle said this ability was extremely Center. And it all starts with a strand of valuable in one case where a patient’s lung DNA. biopsy showed visible signs of fungus on There are no petri dishes growing the smear, yet the tissue sample was not cells in their labs. Instead, the team uses growing the fungus. The PCR test was able sophisticated processes and equipment to isolate and replicate the specifi c DNA to test samples of blood, fl uid, or tissue. strand, and identify the pathogen. Using a method called polymerase chain Yet Fahle said it isn’t all about the reaction (PCR), they selectively amplify technology. The key is the staff. “There is and replicate DNA, looking for a virus, always a new stream of people coming in bacteria, fungus, or other disease-caus- with new ideas. It’s about bringing in the ing organism. new technology, bringing in those new “So if you are looking to see if some- ideas, and fi guring out how to adapt that one has some kind of viral infection, into our clinical world,” he said. you determine that there is a particular Connecting what they do to the clinical region in their DNA that is unique to just setting is essential, added medical technol- that pathogen,” explains Gary Fahle, di- ogist Jennifer Boyer. The team may work rector of the Molecular Diagnostics Ser- in a controlled setting, visually removed vice in the CC Department of Laboratory from the patient-care fl oors. However, they Medicine. “Then you focus on just that never forget that what they do is essential piece of DNA, and you amplify it billions to the CC’s mission and to each individual of times in a small tube in your reaction. patient. Once you have created so many copies “You always think: that is someone’s of that DNA, it is then relatively easy to mom or that is someone’s child. And it hits detect if it is there.” home a little bit because you want to get The benefi t to CC researchers and an answer and you want to help them as Jennifer Boyer, a DLM Molecular Diagnostics patients is rapid diagnosis, a comple- fast as possible,” said Boyer. Service technologist, pipettes into DNA. ment to the many services offered by the Department of Laboratory Medicine. “Some people get very confused and think it is very complicated—PCR and amplifying DNA. It seems like something that is a very complex concept, but it’s really not. It’s really an elegantly simple thing to do,” Fahle said. PCR is not a new scientifi c technique, though traditionally it is most often used in research. At the CC, PCR is used throughout the research process, from the bench to the bedside. “It has always been a research tool and what we are doing in the Clinical Center is taking that research technol- ogy and bringing it into the clinical lab,” said Fahle. Fahle said the patient population of the CC is one aspect that makes the use of molecular diagnostics so important. Compared to other research hospitals, the CC’s patients tend to have more ill- nesses, rare diseases, and compromised immune systems. This means that the molecular diagnostics team runs a high volume of tests and also develops new CC Department of Laboratory Medicine staff member Jeff Brocious uncaps blood samples as he tests, known as assays, for conditions prepares to enter them into a DNA extractor. The extractor selectively amplifi es and replicates DNA to that may be less common in the United search for viruses, bacteria, or other disease-causing organisms.

August 2011 Clinical Center news 5 Former pediatric patient gives back to CC community Former Clinical Center pediatric patient and current AIDS activist Joey DiPaolo returned to the CC and The Children’s Inn at NIH July 11. DiPaolo was one of the fi rst pediatric HIV-positive patients at the CC and one of The Inn’s fi rst residents. This month’s visit, his fi rst in 19 years, was inspired by his foundation’s contribution to The Children’s Inn’s annual summer program, Camp INNcredible. The Joey DiPaolo AIDS Foundation brought its own camp on wheels, Camp TLC (Together Living a Challenge), to Inn residents for the entire week. Camp TLC is a mobile performing and creative arts Present to celebrate the fi rst day of Camp TLC were (from left) Benjamin Banks, DiPaolo’s longtime camp that visits shelters and hospitals friend and fellow CC patient; Joey DiPaolo, AIDS activist and former CC patient; Caroline Baumis, across the country where children are Camp TLC director; and Carol DiPaolo, Joey’s mom. living in isolated situations. After learning that her son was Benjamin Banks were thrilled to tour The to the staff and kids here,” DiPaolo said. infected with the HIV virus at the age Inn and the CC’s new facilities. “The Clini- “I was once in their shoes, and it was of 4 from a blood transfusion during cal Center was a huge hole in the ground always great when people rolled up their open-heart surgery, DiPaolo’s mother the last time I was here,” he said, marvel- sleeves and gave back to the kids and Carol searched for clinical trials all over ing at the new space. “It was always really the community.” the country. After being turned away comfortable here, but this is amazing.” DiPaolo and his mother started the from many research institutions that DiPaolo was impressed with all the Joey DiPaolo AIDS Foundation in 1996. were not yet doing pediatric research, changes and additions at The Inn. He and Inspired after attending the fi rst and only she found hope at the CC. Doctors in Banks were kids again in The Children’s Inn AIDS-related summer camp program in their hometown had said DiPaolo had game room and reminisced about explor- the country at the time. only one year to live. Now, at the age ing the CC and causing trouble through Together, the DiPaolos have imple- of 31, DiPaolo, his mother, and fellow the building as young inpatients. mented more than 500 AIDS prevention former CC patient and long-time friend “I am looking forward to giving back and education programs nationwide.

NEW CLINICAL RESEARCH PROTOCOLS

The following new clinical research protocols were approved in June:

A Pilot Study to Evaluate the A Phase II Trial In Which Patients With A Phase 1b Open-Label, Effect of Acupuncture on Epigenetic Metastatic Alveolar Soft Part Sarcoma Randomized Clinical Trial to Evaluate Regulation of Infl ammatory Mediators Are Randomized to Either Sunitinib or Early Innate and Adaptive Immune in Participants with Chronic Low Cediranib Monotherapy, With Cross-Over Responses to the Investigational HIV- Back Pain; 11-AT-0188; Dr. Lai Wei; at Disease Progression; 11-C-0200; Dr. 1 Vaccines: VRC-HIVADV014-00-VP NCCAM Shivaani Kummar; NCI and VRC-HIVDNA016-00-VP in Ad5 Seronegative Healthy Adults; 11-I- A Phase II Study of TRC105 An Extended Phase II Study of 0197; Dr. Julie E. Ledgerwood; NIAID in Patients with Hepatocellular Decitabine in Subjects with High Risk Sickle Carcinoma (HCC) Who Have Cell Disease; 11-H-0184; Dr. Matthew M. Smith-Lemli-Opitz Syndrome: Progressed on Sorafenib; 11-C-0181; Hsieh; NHLBI A Longitudinal Clinical Study of Dr. Tim F. Greten; NCI Patients Receiving Cholesterol The Natural History, Immunologic Supplementation; 11-CH-0179; Dr. Phase I Trial of Escalating Doses Correlates and Genetic Defects in Patients Forbes D. Porter; NICHD of CT-011 in Combination with p53 with Mucocutaneous and Invasive Fungal Vaccine in Adults with Advanced Infections; 11-I-0187; Dr. Michail S. Biochemical and Genetic Solid Tumors; 11-C-0198; Dr. Samir N. Lionakis; NIAID Mechanisms for Etiology of Sickle Khleif; NCI Cell Pain; 11-NR-0189; Dr. Alan N. Screening of Volunteers for Infl uenza Schechter; NINR A Phase I Trial of Peptide-Based Human Challenge Studies; 11-I-0183; Dr. Glioma Vaccine IMA950 in Patients Matthew J. Memoli; NIAID with Glioblastoma (GBM); 11-C-0191; Dr. Katherine E. Warren; NCI

6 Clinical Center news August 2011 Teen Retreat reminds patients of identity beyond illness Over hot pizza and to the tune of Top 40 Tuesday night it’s as if they’ve known each surgeries—I wouldn’t be who I am to- jams, teenagers laughed at their shared other their whole lives and connected day. I wouldn’t be as strong as I am. But quirks and chatted about favorite video at a level we can’t really quite get,” said what I’ve gained from this is strength games. A scene out of any shopping Recreation Therapy Section Chief Donna and a better, positive attitude,” said mall or high school cafeteria, this inter- Gregory, who has been with the retreat Tristan Hanson, 14-year-old CC patient. action took place in the Clinical Center since it began fi ve years ago. One of the highlights of the Teen Re- main playroom on June 27 at the annual During two days of a pancake break- treat is a panel of survivors of an illness Teen Retreat. fast, fi eld day games, and a collective art or condition they suffered from while A collaboration between the Clinical project, teens meet others who are going a teenager. “We have one young adult Center Rehabilitation Medicine Depart- through similar challenges. “It just shows who is an amputee, and he shares his ment Recreation Therapy Section and the teens that they are a part of something story of being diagnosed at 18. And he’s The Children’s Inn at NIH, the Teen bigger and they are not their illness,” said now in medical school,” said Gregory. Retreat unites young adult patients over Bridget Kuzma, The Children’s Inn family “So it sends the message to these teen- good times and therapeutic events. program and community outreach coordi- agers, who are wise beyond their years, “One of the most rewarding things nator. that there is life after treatment.” for me is to watch them meet for the “If I hadn’t been through what I have fi rst time on Monday morning and by been through—I’ve been through tons of

Recreation Therapy Section Chief Donna Gregory dances with patient Sofi a Silva at the Teen Retreat while recreation therapist Drew Robin- Recreation Therapy section intern Brandon Fitts (center) plays a game son goofs behind her. with Michael Ortiz (left) and Juan Carlos Guerrero Lira. Summer medical and dental training program students visit CC A group of undergraduate students enrolled in the Robert Wood Johnson Foundation Summer Medical and Dental Education Program at Howard University visited the Clinical Center on June 28. This program is designed to strengthen the overall academic preparation of un- derrepresented minority, disadvantaged, and low-income students who are interested in pursuing medical or dental school later in their careers. The group heard a presentation about the NIH and available training opportunities from the CC Offi ce of Clinical Research Training and Medical Education. Students also toured key CC research facilities, including the National Heart, Lung, and Blood Institute’s Vascu- lar Biology Branch where they recieved a presentation from Dr. Gregory Kato head Dr. Gregory Kato (second, from left) explained to some of the visiting Robert Wood Johnson Founda- of the Sickle Cell Vascular Disease Unit in tion students how a normal volunteer’s blood fl ow is evaluated and how it compares to the blood circulation in patients with sickle cell disease. the NHLBI.

August 2011 Clinical Center news 7 Clinical Center Hospitality lends more than a smiling face By: Kacey Ford Grand Rounds The smiling faces and helpful directions Lipsett Amphitheater, 12 noon from the Clinical Center Hospitality Lectures will be videocast at Services staff are more than a welcom- http://videocast.nih.gov. ing greeting to new and returning patients, they are vital to the every- August 3 day functions and operations of the hospital. The Role of NIH in Ensuring a Bright On July 27, CAPT Denise Ford, de- Future for Physician-Scientists partment chief, held a Hospitality Ap- preciation Day to recognize and thank Leon Rosenberg, MD the employees for their dedication and Professor, Department of Molecular Biology, exemplary service to the CC mission. Princeton University Hospitality staff are designated to front line service areas in Radiology, Phar- macy, Admissions, and the West Drive August 10 Patient Entrance, as well as stationed The CC celebrated Hospitality Appreciation Day at dedicated CC hospitality desks. At a and the the exemplary commitment and service Collaborative/Team Science: Impact and luncheon, Ford told the hospitality staff of the Hospitality Services staff on July 27. Implementation that they are more than people who stand behind an information desk and answer questions. They play an extremely Ann Bonham, PhD important role throughout the hospital to create a special experience for our pa- Chief Scientifi c Offi cer, Association of tients and family members. American Medical Colleges “I love helping the patients and guiding them to wherever they need to go,” said Tish Johnson, who works at the West Drive patient entrance and the CC north entrance hospitality desk. “Knowing that they go through so much pain and suf- August 17 fering motivates me to make their experience here special. When I see a smile on their face, it gives me the best feeling.” Safeguarding Sound Science: Avoiding the Common Pitfalls of Clinical Research Misconduct Sino-American symposium focuses on translational research Kristen Grace, MD, PhD Scientist-Investigator, Offi ce of Research Dr. John I. Gallin, Clinical Center health, delivered the keynote address. Integrity, Division of Investigative Oversight, director, and Dr. Shengli Yang, a Organizers for the event were the CC, Department of Health and Human Services member the Chinese Academy of the Chinese Academy of Engineering, Engineering’s governing board, the Chinese Academy of Medical Sci- co-chaired the 2nd Sino-American ences, and GlobalMD. August 24 Symposium on Clinical and Transla- In the last two years, the CC has tional Medicine in Shanghai, China, introduced to China two courses from A Long and Winding Road: National in June. the NIH intramural clinical research Health Reform and the Future of Gallin noted that the goal of the curriculum, Principles and Practice of American Health Care assembly was to offer scientifi c lead- Clinical Research and Clinical Phar- ers from the United States and from macology. The NIH faculty have made Sara Rosenbaum, JD China opportunities to discuss how four teaching visits to China and have Harold & Jane Hirsh Professor, Department to stimulate translational science provided training to 3,000 physicians of Health Policy, School of Public Health and and sustain a robust clinical research and nurses in more than 500 hospitals Health Services, The George Washington program. and research institutes in China using University Medical Center “In China, there is acute aware- both live courses and long-distance ness of the importance of transla- learning tools. tional research,” said Gallin, “from Two of the courses’ textbooks have August 31 bench to bedside and back to the been translated into Chinese, and the bench. Improving health for everyone Chinese are now beginning to teach The Therapeutic Misconception and in China is an important national the courses on their own. An outcome Informed Consent agenda there. Medical and scientifi c of these training efforts was the 1st leaders understand that exploring Sino-American Clinical Research Sum- Franklin G. Miller, PhD opportunities for innovations in the mit, held June 16-18, 2010, which Senior Staff Bioethicist, Department of conduct of clinical research can help Gallin co-chaired with Dr. Depei Liu, Bioethics, Clinical Center, NIH fulfi ll that agenda.” president of the Chinese Academy of Dr. Zhu Chen, China’s minister of Medical Sciences.

8 Clinical Center news August 2011