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Pharmacy Operations and Drug Scheduling Act DRUG SCHEDULES REGULATION B.C. Reg. 9/98 Deposited and effective January 9, 1998 Last amended June 28, 2018 by B.C. Reg. 137/2018 Consolidated Regulations of British Columbia This is an unofficial consolidation. Point in time from June 28 to December 6, 2018 B.C. Reg. 9/98 (O.C. 35/98), deposited and effective January 9, 1998, is made under the Pharmacy Operations and Drug Scheduling Act, S.B.C. 2003, c. 77, s. 22. This is an unofficial consolidation provided for convenience only. This is not a copy prepared for the purposes of the Evidence Act. This consolidation includes any amendments deposited and in force as of the currency date at the bottom of each page. See the end of this regulation for any amendments deposited but not in force as of the currency date. Any amendments deposited after the currency date are listed in the B.C. Regulations Bulletins. All amendments to this regulation are listed in the Index of B.C. Regulations. Regulations Bulletins and the Index are available online at www.bclaws.ca. See the User Guide for more information about the Consolidated Regulations of British Columbia. The User Guide and the Consolidated Regulations of British Columbia are available online at www.bclaws.ca. Prepared by: Office of Legislative Counsel Ministry of Attorney General Victoria, B.C. Point in time from June 28 to December 6, 2018 Pharmacy Operations and Drug Scheduling Act DRUG SCHEDULES REGULATION B.C. Reg. 9/98 Contents 1 Alphabetical order 2 Sale of drugs 3 [Repealed] SCHEDULES Alphabetical order 1 (1) The drug schedules are printed in an alphabetical format to simplify the process of locating each individual drug entry and determining its status in British Columbia. (2) Each entry is preceded by a code noted as 1, 1A, 2, 3 or 4, in which 1 = Schedule I 1A = Triplicate/Duplicate Prescription Program 2 = Schedule II 3 = Schedule III 4 = Schedule IV. Sale of drugs 2 (1) Drugs listed in Schedules I, IA, II, III and IV must be sold from licensed pharmacies. (2) Unscheduled drugs may be sold from non-pharmacy outlets. (3) The various schedules are differentiated as follows: Schedule I (Prescription): Schedule I drugs require a prescription for sale and are provided to the public by a pharmacist following the diagnosis and professional intervention of a practitioner. The sale is controlled in a regulated environment as defined by provincial pharmacy legislation. Entries followed by a “V” superscript may be sold without having received a prescription if (a) the drug is in a form not suitable for human use, or (b) the main panel of the manufacturer’s inner label and the manufacturer’s outer label carry, in both official languages, the statement “For Veterinary Use Only” or “For Agricultural Use Only” immediately following or preceding the brand name, proper name or common name, in type size not less than one-half as large as the largest type on the label, and the product is sold in the original manufacturer’s container. Schedule IA (Triplicate/Duplicate Prescription Program): Drugs which may be sold by a pharmacist to a practitioner or on the prescription of a practitioner in Last amended June 28, 2018 1 Point in time from June 28 to December 6, 2018 B.C. Reg. 9/98 PHARMACY OPERATIONS AND DRUG SCHEDULING ACT DRUG SCHEDULES REGULATION Schedules accordance with Bylaw 5 (31) (6) of the bylaws to the Pharmacists, Pharmacy Operations and Drug Scheduling Act. Schedule II (Professional Service Area): Drugs which may be sold by a pharmacist on a non-prescription basis and which must be retained within the Professional Service Area of the pharmacy where there is no public access and no opportunity for patient self-selection. Schedule III (Professional Products Area): Drugs which may be sold by a pharmacist to any person from the self-selection Professional Products Area of a licensed pharmacy. Schedule IV (Prescription by Pharmacist): Drugs which may be prescribed by a pharmacist in accordance with guidelines approved by the Council. Unscheduled (Non-pharmacy Sale): Drugs which may be sold by a non- pharmacist to any person. [am. B.C. Regs. 312/2001; 210/2002.] 3 Repealed. [B.C. Reg. 418/98.] SCHEDULES [am. B.C. Regs. 9/98; 141/98; 418/98; 247/99; 31/2000; 355/2000; 377/2000; 378/2000; 132/2001; 211/2001; 312/2001; 21/2002; 210/2002; 232/2002; 233/2002; 288/2002; 19/2003; 303/2003; 142/2006; 169/2006; 137/2007; 200/2008; 45/2009; 46/2009; 286/2009; 2/2011; 64/2011; 189/2011; 190/2011; 192/2012; 180/2015; 181/2015; 83/2016; 160/2016; 230/2016; 279/2016; 6/2017, s. (b); 137/2018.] 1 Abacavir and its salts 1 Abatacept 1Abciximab 1 Acamprosate and its salts 1 Acarbose and its derivatives 1 Acebutolol and its salts 1 Acepromazine and its saltsV 1 Acetaminophen, when recommended for administration by intravenous injection 3 Acetaminophen (in sustained-release formulations containing greater than 650 mg per unit or in package sizes greater than 50 units) 1 AcetanilideV 2Acetarsol 1 Acetazolamide 1 Acetohexamide 1 Acetylcarbromal 1 Acetylcholine Chloride 2 Acetylcysteine 1 Acetylsalicylic acid and its salts (in oral preparations containing 80 mg or less per dosage unit in containers with more than 24 dosage units per container) 2 Acetylsalicylic acid and its salts (in oral preparations containing 80 mg or less per dosage unit in child-resistant containers with 24 or less dosage units per container or rectal preparations containing 150 mg or less per dosage unit) V Prescription not required if sold for veterinary use, provided that the product is labelled by the manufacturer “for agricultural use only” or “for veterinary use only” 2 Last amended June 28, 2018 Point in time from June 28 to December 6, 2018 PHARMACY OPERATIONS AND DRUG SCHEDULING ACT B.C. Reg. 9/98 DRUG SCHEDULES REGULATION Schedules 3 Acetylsalicylic acid and its salts (in products intended for oral use by adults in strengths of 81 mg per dosage unit and 650 mg or greater per dosage unit and in rectal preparations containing more than 150 mg per dosage unit) 1 Acitretin and its salts and derivatives 1 Aconiazide and its salts 1 Acyclovir and its salts 1 Adalimumab 1 Adapalene and its salts and derivatives 1 Adefovir and its salts and derivatives 1 Adenosine or its salts when sold or recommended for administration by intravenous injection 2 Adiphene and its salts for parenteral use 1 Adrenocortical hormones and their salts and derivativesV, including but not limited to betamethasone dipropionate, betamethasone phosphate, betamethasone sodium, betamethasone valerate, budesonide, ciclesonide, clobetasone, cortisone, dexamethasone acetate, dexamethasone phosphate, dexamethasone sodium, difluprednate, fludrocortisone acetate, flunisolide, fluticasone furoate, fluticasone propionate, hydrocortisone aceponate, hydrocortisone acetate, hydrocortisone sodium, methylprednisolone acetate, methylprednisolone, methylprednisolone sodium, methylprednisolone succinate, mometasone furoate, prednisolone acetate, prednisolone phosphate, prednisolone sodium, prednisone, triamcinolone acetonide, triamcinolone hexacetonide (except (a) hydrocortisone or hydrocortisone acetate, when sold as a single medicinal ingredient in a concentration that provides 1% or less hydrocortisone in preparations for topical use on the skin, (b) hydrocortisone or hydrocortisone acetate, when sold in combination with any other non- prescription medicinal ingredient that provides 1% or less hydrocortisone in preparations for topical use on the skin, (c) clobetasone butyrate, when sold in a concentration of 0.05% in cream preparations for topical use on the skin, (d) fluticasone propionate, when sold for the treatment of allergic rhinitis in a nasal spray that delivers 50 mcg per metered spray for individuals 18 years of age and older), (e) mometasone furoate for the treatment of allergic rhinitis in a nasal spray that delivers 50 mcg per spray for those 12 years of age and older, and (f) triamcinolone acetonide in a nasal spray that delivers 55 mcg per spray for adults and children 12 years of age and older 1 Agalsidase alfa 1 Alatrofloxacin and its salts and derivatives 1 Aldesleukin 1Alefacept 1 Alemtuzumab 1 Alendronic acid and its salts 1 Alfacalcidol 1A Alfentanil 1 Alfuzosin and its salts 1 Aliskiren and its salts 1 Alkyl nitrites 1 Allergy serums 2 Allethrins (pyrethrins) V Prescription not required if sold for veterinary use, provided that the product is labelled by the manufacturer “for agricultural use only” or “for veterinary use only” Last amended June 28, 2018 3 Point in time from June 28 to December 6, 2018 B.C. Reg. 9/98 PHARMACY OPERATIONS AND DRUG SCHEDULING ACT DRUG SCHEDULES REGULATION Schedules 1 Allopurinol 1 Allylisopropylacetylurea 1 Almotriptan and its salts 3 Aloe vera latex, its extracts and derivatives (except aloin) (dosage forms for systemic use containing more than 300 mg per dosage unit) 1 Alpha-chloralose 1 Alphadolone and its salts 1 Alphaxalone 1 Alprazolam 1 Alteplase and its salts and derivatives 1 Altrenogest 1 Altretamine 3 Aluminum oxide 1 Alverine and its salts (for parenteral use) 1 Amantadine and its salts 1 Ambenonium chloride 1Ambrisentan 1 Amifostine and its salts 1 Amikacin and its salts and derivatives 1 Amiloride and its salts 1 4-Amino-pteroyl aspartic acid and its salts 1 Amino acid solutions (for parenteral use) 1 Aminocaproic acid 1 Aminoglutethimide 1 Aminolevulinic acid and its salts and derivatives 1 Aminophylline 1 Aminopromazine [proquamezine] and its salts 1 Aminopterin and its salts 1 Aminopyrine and its derivativesV
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  • Phosphodiesterase (PDE)

    Phosphodiesterase (PDE)

    Phosphodiesterase (PDE) Phosphodiesterase (PDE) is any enzyme that breaks a phosphodiester bond. Usually, people speaking of phosphodiesterase are referring to cyclic nucleotide phosphodiesterases, which have great clinical significance and are described below. However, there are many other families of phosphodiesterases, including phospholipases C and D, autotaxin, sphingomyelin phosphodiesterase, DNases, RNases, and restriction endonucleases, as well as numerous less-well-characterized small-molecule phosphodiesterases. The cyclic nucleotide phosphodiesterases comprise a group of enzymes that degrade the phosphodiester bond in the second messenger molecules cAMP and cGMP. They regulate the localization, duration, and amplitude of cyclic nucleotide signaling within subcellular domains. PDEs are therefore important regulators ofsignal transduction mediated by these second messenger molecules. www.MedChemExpress.com 1 Phosphodiesterase (PDE) Inhibitors, Activators & Modulators (+)-Medioresinol Di-O-β-D-glucopyranoside (R)-(-)-Rolipram Cat. No.: HY-N8209 ((R)-Rolipram; (-)-Rolipram) Cat. No.: HY-16900A (+)-Medioresinol Di-O-β-D-glucopyranoside is a (R)-(-)-Rolipram is the R-enantiomer of Rolipram. lignan glucoside with strong inhibitory activity Rolipram is a selective inhibitor of of 3', 5'-cyclic monophosphate (cyclic AMP) phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM phosphodiesterase. and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. Purity: >98% Purity: 99.91% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 10 mg, 50 mg (R)-DNMDP (S)-(+)-Rolipram Cat. No.: HY-122751 ((+)-Rolipram; (S)-Rolipram) Cat. No.: HY-B0392 (R)-DNMDP is a potent and selective cancer cell (S)-(+)-Rolipram ((+)-Rolipram) is a cyclic cytotoxic agent. (R)-DNMDP, the R-form of DNMDP, AMP(cAMP)-specific phosphodiesterase (PDE) binds PDE3A directly.
  • Partial Agreement in the Social and Public Health Field

    Partial Agreement in the Social and Public Health Field

    COUNCIL OF EUROPE COMMITTEE OF MINISTERS (PARTIAL AGREEMENT IN THE SOCIAL AND PUBLIC HEALTH FIELD) RESOLUTION AP (88) 2 ON THE CLASSIFICATION OF MEDICINES WHICH ARE OBTAINABLE ONLY ON MEDICAL PRESCRIPTION (Adopted by the Committee of Ministers on 22 September 1988 at the 419th meeting of the Ministers' Deputies, and superseding Resolution AP (82) 2) AND APPENDIX I Alphabetical list of medicines adopted by the Public Health Committee (Partial Agreement) updated to 1 July 1988 APPENDIX II Pharmaco-therapeutic classification of medicines appearing in the alphabetical list in Appendix I updated to 1 July 1988 RESOLUTION AP (88) 2 ON THE CLASSIFICATION OF MEDICINES WHICH ARE OBTAINABLE ONLY ON MEDICAL PRESCRIPTION (superseding Resolution AP (82) 2) (Adopted by the Committee of Ministers on 22 September 1988 at the 419th meeting of the Ministers' Deputies) The Representatives on the Committee of Ministers of Belgium, France, the Federal Republic of Germany, Italy, Luxembourg, the Netherlands and the United Kingdom of Great Britain and Northern Ireland, these states being parties to the Partial Agreement in the social and public health field, and the Representatives of Austria, Denmark, Ireland, Spain and Switzerland, states which have participated in the public health activities carried out within the above-mentioned Partial Agreement since 1 October 1974, 2 April 1968, 23 September 1969, 21 April 1988 and 5 May 1964, respectively, Considering that the aim of the Council of Europe is to achieve greater unity between its members and that this