Corman-Drosten Review Report
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Compendium of the Findings of the OPCAST Pandemic Subgroup 12
1 A Compendium of the Findings of the Obama PCAST Ad Hoc Subgroup on Pandemic Preparedness and Response December 23, 2020 Introduction A subset of the former members of President Obama’s Council of Advisors on Science and Technology (here OPCAST)—ten individuals who played particularly important roles in producing the six OPCAST reports between 2009 and 2016 that dealt with issues related to pandemic preparedness and response1—came together starting in March of this year to consider how insights from those studies might be combined with more recent research and current observations to develop suggestions about how the U.S. response to the COVID-19 pandemic could be improved. The Subgroup has produced six reports, addressing • the national strategic pandemic-response stockpile (May 20) • the role of contact tracing (June 18) • the role of public health data in controlling the spread of COVID-19 (July 28) • testing for the pathogen (August 18) • recommendations for the coming COVID-19 commission (September 21) • needs for improved epidemiological modeling (September 28) Each report was distributed, upon completion, to selected members of the Trump COVID-19 team and the Biden campaign staff, selected governors and members of Congress, selected public health experts outside government, and the media. The reports have also been posted on the OPCAST team’s website, http://opcast.org, together with a few opinion pieces based on them. In the current volume, we have assembled all six reports in full, preceded by a set of brief summaries. Four of the reports are followed by short updates taking account of developments since the reports first came out. -
Principais Vozes Da Ciência No Twitter
Principais vozes da ciência no Twitter: Mapeando a conversa de cientistas e especialistas sobre a COVID-19 UMA ANÁLISE DA REDE DE INTERAÇÕES NO TWITTER 1 O Science Pulse é uma ferramenta gratuita de social O Instituto Brasileiro de Pesquisa e Análise de Dados é um listening criada para preencher a lacuna entre jornalistas e centro independente de pesquisa e formação de analistas e cientistas. O objetivo é ajudar jornalistas a encontrar pesquisadores nas áreas de Pesquisa, Opinião Pública e conteúdos científicos que são tendência nas redes sociais e Comunicação Digital. a conhecer novos especialistas. O foco do Instituto é a aplicação e o ensino de técnicas e Com um algoritmo próprio, facilita a descoberta das metodologias de análise de dados com sólida formação publicações com maior popularidade dentro da comunidade científica para atuação no mercado. científica, das principais hashtags utilizadas e de perfis interessantes com menor engajamento. Conheça a nossa formação em Data Intelligence com curso exclusivo sobre Análise de Redes! O projeto foi criado pelo Volt Data Lab, agência do ICFJ Knight Fellow Sérgio Spagnuolo, e conta com apoio institucional da Agência Bori. 2 EXPEDIENTE Pesquisador Responsável Pedro Meirelles Coleta dos dados Science Pulse Tratamento dos dados IBPAD - Instituto Brasileiro de Pesquisa e Análise de Dados COMO CITAR? MEIRELLES, Pedro. Principais vozes da ciência no Twitter: Mapeando a conversa de cientistas e especialistas sobre a COVID-19. Relatório. Instituto Brasileiro de Pesquisa e Análise de Dados (IBPAD): Brasília, 2020. 3 METODOLOGIA A rede de interações foi desenvolvida a partir da base de dados do Science Pulse, que reuniu 213.469 publicações de cientistas, especialistas e organizações da comunidade científica sobre a SOBRE O RELATÓRIO COVID-19 entre junho e outubro de 2020. -
Legal-Graphics' 2-19-21 COVID Timeline
Number of days Overview: Year 2 of COVID since first sign of virus Nov. 23, 2020 Dec. 3, 2020 Dec. 11, 2020 Dec. 21, 2020 Dec. 30, 2020 Worldwide Worldwide Worldwide Worldwide Worldwide Coronavirus Deaths Coronavirus Deaths Coronavirus Deaths Coronavirus Deaths Coronavirus Deaths Link to Source over 1,400,000 over 1,500,000 over 1,600,000 over 1,700,000 over 1,800,000 Signs of Virus 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 Key Events Nov. 16, 2020 Nov. 18, 2020 Nov. 21, 2020 Nov. 25, 2020 Nov. 27, 2020 Nov. 30, 2020 Dec. 3, 2020 Dec. 6, 2020 Dec. 8, 2020 Dec. 11, 2020 Dec. 14, 2020 Dec. 17, 2020 Dec. 21, 2020 Dec. 22, 2020 Dec. 26, 2020 Dec. 29, 2020 Dec. 31, 2020 Jan. 3, 2021 Good News! Moderna says data FDA allows US cases top Picture of US Demand for live Moderna to request Map showing US UK gears up for Chart of cumulative Pfizer vaccine to be How do the Pfizer Vaccinations reach How the Pfizer Vaccines across Could AZD7442 Map showing How vaccinations Interactive US Map shows its vaccine 1st rapid virus test 12 million ... spread economy is Christmas trees emergency states with the huge vaccination number of deaths OK’d in days - and Moderna US nursing homes and Moderna the world prevent COVID-19 which countries were developed by county showing Legal Matters is more than that gives results 'faster' and 'broader' worrisome skyrockets amid authorization their highest number plan watched by country (by “normal” next fall vaccines work? vaccines compare infection have rolled out so quickly risk for COVID 94% effective at home than ever as virus toll of virus coronavirus vaccine of virus deaths by the world number of days in those exposed? a COVID-19 vaccine inflicts damage since 100 deaths Dec. -
Emerging Leaders in Biosecurity Initiative
Emerging Leaders in Biosecurity Initiative Class of 2017 A competitive fellowship program created to identify, develop, and provide networking opportunities Yearbook for the next generation of leaders in biosecurity. Emerging Leaders in Biosecurity Initiative Contents Letter: 3 Thomas V. Inglesby, Director; Anita Cicero, Deputy Director, Johns Hopkins Center for Health Security Executive Steering Committee 5 Class of 2017 Fellows 9-35 ELBI 2017 Year in Review 36-37 ELBI Program Staff 41 ELBI Alumni 42 Cover and Inside Cover Photo Overlay: Swine Flu Strain Virus Particles. Col- orized transmission electron micrograph of negatively stained SW31 (swine strain) influenza virus particles. Credit: NIAID Emerging Leaders in Biosecurity Initiative The ELBI Fellowship program is made possible through financial support from the Open Philanthropy Project, under management by the Johns Hopkins Center for Health Security, and with the leadership of the ELBI Executive Steering Committee. For more information, please visit the ELBI website: http://www.centerforhealthsecurity.org/our-work/emergingbioleaders Center for Health Security “Modern conditions make the scenario of a global pandemic more likely. Humans are encroaching on animal environments, raising chances for pathogens to adapt from animals to people. An increasing share of the planet lives in megacities, heightening the likelihood of person-to-person transmission of pathogens. The movement of people and microbes around the globe is more efficient than ever. The recent outbreaks of SARS, MERS, and Ebola are only small glimpses of how quickly a deadly virus can spread.” Tom Inglesby and Benjamin Haas Foreign Affairs November 21, 2017 Middle East Respiratory Syndrome Coronavirus particle envelope proteins immunolabeled with Rabbit HCoV-EMC/2012 primary antibody and Goat an- 1 ti-Rabbit 10 nm gold particles. -
Questions & Answers on Influenza
101 Questions & Answers on Influenza101 101 Questions & Answers Prof. Dr. A.D.M.E. (Ab) Osterhaus is David De Pooter is working at Link Inc on professor of virology at Erasmus Medical since 2003, the Antwerp (Belgium) based Centre Rotterdam, and professor of communication consultancy agency, Environmental Virology at the Utrecht specialised in strategic communication University. Fascinated by the ingenious and social marketing. Link Inc is working ways viruses circumvent the immune with the European Scientific working Influenza system of their hosts to multiply and Group on Influenza (ESWI) since 1998 and spread, Osterhaus started his quest at the is taking care of the positioning of the interface of virology and immunology. He group, the strategy and the implementa Ab Osterhaus quickly translated new insights in this tion of the strategy by developing complex field to applications in animal and targeted communication tools. In this human vaccinology. In addition, he started capacity, David De Pooter is a professional David De Pooter his work on virus discovery, not only writer on medical topics and a communi focussing on the identification of a series cation manager of ESWI. As such he has of animal viruses, but also of new human established a fruitful and long standing viruses. collaboration with Prof Ab Osterhaus. (www.linkinc.be) 101 Questions & Answers on Influenza 101 101 Questions & Answers on Influenza Ab Osterhaus David De Pooter Elsevier, Maarssen © Elsevier, Maarssen 2009 Design: Studio Bassa, Culemborg Elsevier is an imprint of Reed Business bv, PO Box 1110, 3600 BC Maarssen, The Netherlands. To order: Elsevier Gezondheidszorg, Marketing dept., Antwoordnummer 2594 (freepost), 3600 VB Maarssen, The Netherlands. -
"Pandemieën Bij Mens En Dier: Zijn We Er Op Voorbereid?" Prof. Ab Osterhaus DVM
"Pandemieën bij mens en dier: zijn we er op voorbereid?" Prof. Ab Osterhaus DVM PhD Director Research Center for Emerging Infections and Zoonoses (RIZ) University of Veterinary Medicine Hannover, Germany MSD Webinar, januari 22 2021 Rinderpest 1745: The Netherlands 2003: Last case in Mauretania 2011: Eradicated 1980 1990 2000 2010 2020 Past decades: zoonoses at the origin of major human disease outbreaks pandemics Adapted from: Reperant LA, Cornaglia G, Osterhaus AD Curr Top Microbiol Immunol.2013 The importance of understanding the human-animal interface: from early hominins to global citizens Most recent outbreaks of avian influenza as reported to the OIE in the last 6 months. African swine fever African swine fever Crucial elements for pandemic preparedness to be established in ‘peacetime’ • Early warning systems • Pathogen discovery and characterization platforms • Diagnostic platforms • Mathematical models • Animal models in BSL3 facilities • Clinical trial platforms • Non-pharmaceutical intervention and treatment strategies • Pharmaceutical intervention strategies •antiviral platforms •vaccine platforms •BRM platforms • Communication 8 25.01.2021 Last four influenza pandemics Credit: US National Museum of Health and Medicine 1918 1957 1968 2009 “Spanish Flu” “Asian Flu” “Hong Kong Flu” “Mexican flu” >40 million deaths 1-4 million deaths 1-4million deaths 0.2-0.6 million deaths A(H1N1) A(H2N2) A(H3N2) A(H1N1) Within a few weeks, the 2009 H1N1 pandemic spread around the world affecting all countries April 2009 May 2009 START June 2009 March 2009 July 6 2009 Cumulative cases 1–10 11–50 51–500 500–5000 Air traffic from Mexico >5000 De Jong et al., Nature 1997 Claas & Osterhaus, Nat.Med 1998 Fouchier et al., J Virol., 2005 Munster et al., EID., 2005 Aquatic wild birds Olsen et al., Science., 2006 Influenza A virus reservoir BF Koel et al, Science. -
National Covid-19 Testing & Tracing Action Plan
National Covid-19 Update Report Testing & Tracing Time to Redouble Our Efforts on Action Plan Covid-19 Testing Embargoed until 12:01am EDT, Thursday, July 16, 2020 THE ROCKEFELLER FOUNDATION NATIONAL COVID-19 TESTING & TRACING ACTION PLAN 1 This terrifying tragedy was not and is not inevi- Foreword table. America can function safely, even as we fight Covid-19. Other countries have shown that a better alternative is possible. But as we said in America faces an impending disaster. April – when we first released The Rockefeller Foundation’s National Covid-19 Testing Action The extraordinary scale of the Plan – testing is the only way out of our present disaster, and it will remain the case until a vaccine Covid-19 crisis is evident in the or effective therapeutics are widely available. growing deaths and economic losses When we were barely a month into this pan- the pandemic has wrought in every demic, we brought together scientists, industry, technologists, economists, and Republicans state. Devastated minority and and Democrats alike to formulate an action plan low-income families bore the brunt of to expedite the development of our nation’s widespread testing and tracing system. We those costs. As the virus tore across called for rapidly expanded diagnostic test- ing capacity from 1 million tests per week to 3 the country, it exposed the structural million tests per week by June, and to 30 million inequities that have underpinned tests per week by October. Today we’re at 4.5 million tests per week, but unfortunately it’s and undermined our economy taking far too long to get to 30 million tests per week, and communities that most need them – for decades. -
Taking Organs-On-A-Chip to the Next Level
#1 Volume 11 October 2020 Medicines is the news magazine of Figon Regenerative pharmacology Taking organs-on-a-chip to the next level In this issue Clémence Ross-van Dorp Towards humans-on-a-chip The FIGON Dutch Medicines Days This former Dutch State Secretary, and Regenerative pharmacology allows an (DMD) are held online this year, throughout keynote speaker at the DMD, was entirely new perspective on human the fall of 2020. Check out the webinars at appointed Ambassador for the Dutch life physiology, health and disease. ‘These figondmd.nl. Keynote speakers are sciences and health sector. She is new methods are more closely related to presenting their topics in this issue. strengthening national networks. the intact human body.’ XXPage 10-27 XXPage 10 XXPage 20 Register via single-use.nu/ event/register Single-Use Event 2020 CORPUS | Leiden | November 10 On November 10th at location CORPUS in Leiden suppliers and users will meet at the ultimate networking event in the world of bioprocessing, biotechnology and (bio)pharmaceutical manufacturing. You are welcome to view and test new products, network with key suppliers in the single-use industry, and attend presentations about the latest developments in single-use. Editorial It takes an entire team he battle against COVID-19 is like the Olympics: a gargantuan international ef- fort with high personal, economic and emotional stakes. In fact, since the Olym- Tpics were cancelled this year, COVID-19 seems to have taken their place. It keeps us addicted to our news sour- ces. It is the talk of the day. And it brings together science, policy, business and societal organisations. -
Curriculum Vitae Ralph S. Baric
Curriculum Vitae Ralph S. Baric I. CONTACT INFORMATION: Department of Epidemiology School of Public Health University of North Carolina at Chapel Hill 2105-D McGaveran-Greenberg Hall, CB# 7400 Chapel Hill, North Carolina 27599-7400 Phone: 919-966-3895 II. EDUCATION: A. North Carolina State University, Raleigh, North Carolina, B.S., Zoology, 1977 B. North Carolina State University, Raleigh, North Carolina, Ph.D., Microbiology, 1983 C. University of Southern California, School of Medicine, Department of Microbiology and Neurology, Post-doctoral Fellow, 1982-1986 III. PROFESSIONAL EXPERIENCE: A. Assistant Professor, Department of Parasitology and Laboratory Practice, University of North Carolina at Chapel Hill, March 1986-June 1990 B. Assistant Professor, Department of Epidemiology, University of North Carolina at Chapel Hill, July 1990-June 1993. C. Associate Professor, Department of Epidemiology, University of North Carolina at Chapel Hill, July 1993-2001. D. Associate Professor, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, July 1993-2001 E. Professor, Department of Epidemiology, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, July 2002-current IV. HONORS AND AWARDS: A. Full Athletic Scholarship, Swimming, North Carolina State University, 1973-1976 B. Atlantic Coast Conference Champion and record holder: 500 yard Freestyle, 1000 yard Freestyle, 1650 yard Freestyle, 400 yard Individual Medley, 800 yard Freestyle Relay C. Teaching Assistantship, North Carolina State University, 1977-1978 D. Agricultural Foundation Pre-doctoral Research Assistantship, 1978-1981 E. Teaching Assistantship, North Carolina State University, 1981-1982 F. NIH Postdoctoral Fellowship, Neurology Training Grant, 1982-1984 G. Harvey Weaver Scholar, National Multiple Sclerosis Society Fellowship, 1984-86 H. -
May 13 Federal Update
Congressional and Federal Agency Responses and Opportunities Regarding the COVID-19 Outbreak Lewis-Burke Associates LLC May 13, 2020 Table of Contents Introduction ................................................................................................................................................. 3 Congressional and Federal Updates ............................................................................................................. 3 Update: Democrats Unveil Proposed $3 Trillion Response Package ........................................................ 3 Update: House, Senate Committees Hold Hearings on COVID-19 Response ........................................... 9 Federal Guidance Related to Research and Higher Education ................................................................... 10 Office of Management and Budget (OMB) ............................................................................................ 10 Update: Department of Education (ED) ................................................................................................. 12 National Institutes of HealtH (NIH) ......................................................................................................... 15 Department of HealtH and Human Services (HHS) ................................................................................. 16 Centers for Medicare and Medicaid Services (CMS) .............................................................................. 16 Food and Drug Administration (FDA) .................................................................................................... -
IHP News 559 : “Public Enemy Number One”
IHP news 559 : “Public enemy number one” ( 14 February 2020) The weekly International Health Policies (IHP) newsletter is an initiative of the Health Policy unit at the Institute of Tropical Medicine in Antwerp, Belgium. Dear Colleagues, I know, I know, it’s Valentine today, so I probably shouldn’t talk about the eerily sounding “Covid- 19” in this short intro, let alone about the even more dreaded “P word” but WHO and dr. Tedros were clearly in no mood for Valentine earlier this week, when describing the virus as “a global threat, potentially worse than terrorism”. “The world must wake up and consider this enemy virus as public enemy number one,” Tedros said. With world media and public opinion going berserk all around the world for a few weeks now, I think that shouldn’t be too much of a problem. The other part of his message, however, that it’s about "solidarity, solidarity and solidarity", might prove much harder in the weeks and months to come, given how Sapiens is wired. When thinking of pandemics, in this visual culture of ours, we probably all have (subconsciously or not) a particular movie in mind when considering some of the most dire scenarios. For some of you, that might be “Contagion”, for me, it’s no doubt “Twelve Monkeys” (1995), with among others, Bruce Willis, a stunning Madeleine Stowe and a young Brad Pitt. Back in the innocent ‘90s, it all felt a bit surreal, even the obligatory rogue scientist popping up towards the end. But what a great movie! Now in the year 2020, with the scary ongoing public health experiment (aka ‘the coronavirus cruise ship quarantines’), occasionally I get the feeling that “Twelve Monkeys” is being mixed up with “the Poseidon Adventure” . -
The Diocese of Southeast Florida's Reopening
On Being Faithful Guidelines for a Shared Discernment on the Way Ahead in this Season of COVID-19 But now thus says the Lord, he who created you, O Jacob, he who formed you, O Israel: Do not fear, for I have redeemed you; I have called you by name, you are mine. For I am the Lord your God, the Holy One of Israel, your Savior. Do not remember the former things, or consider the things of old. I am about to do a new thing; now it springs forth, do you not perceive it? I will make a way in the wilderness and rivers in the desert. [Isaiah 43:1,3,18-19] Preface Little did we know when the forty days of Lent began, that we would end the season in quarantine, either self-imposed, as if in a kind of strict Lenten fast, or enforced by guidelines promoted to protect public health and safety. From the forty (Latin: quaranta) days of Lent we have passed through the remembrance of Christ’s saving death and glorious resurrection into the fifty days of the Easter season, sure that Jesus Christ is risen, but still wondering when it might be safe for us to emerge from our own ‘tombs’ into the light of a new day. The new day has come, but we would do well to acknowledge that it is of a different kind and order, and one which no longer holds any certainty in this COVID-19 world. In this unwelcome season of the COVID-19 virus, we find ourselves living through a period of volatility, uncertainty, complexity, and ambiguity, or, for short, a VUCA season.