ECDC/EFSA Joint Report: Avian Influenza Overview October
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SCIENTIFIC REPORT APPROVED: 29 September 2017 doi: 10.2903/j.efsa.2017.5018 Avian influenza overview October 2016–August 2017 European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian influenza, Ian Brown, Paolo Mulatti, Krzysztof Smietanka, Christoph Staubach, Preben Willeberg, Cornelia Adlhoch, Denise Candiani, Chiara Fabris, Gabriele Zancanaro, Joana Morgado and Frank Verdonck Abstract The A(H5N8) highly pathogenic avian influenza (HPAI) epidemic occurred in 29 European countries in 2016/2017 and has been the largest ever recorded in the EU in terms of number of poultry outbreaks, geographical extent and number of dead wild birds. Multiple primary incursions temporally related with all major poultry sectors affected but secondary spread was most commonly associated with domestic waterfowl species. A massive effort of all the affected EU Member States (MSs) allowed a descriptive epidemiological overview of the cases in poultry, captive birds and wild birds, providing also information on measures applied at the individual MS level. Data on poultry population structure are required to facilitate data and risk factor analysis, hence to strengthen science-based advice to risk managers. It is suggested to promote common understanding and application of definitions related to control activities and their reporting across MSs. Despite a large number of human exposures to infected poultry occurred during the ongoing outbreaks, no transmission to humans has been identified. Monitoring the avian influenza (AI) situation in other continents indicated a potential risk of long-distance spread of HPAI virus (HPAIV) A(H5N6) from Asia to wintering grounds towards Western Europe, similarly to what happened with HPAIV A(H5N8) and HPAIV A(H5N1) in previous years. Furthermore, the HPAI situation in Africa with A(H5N8) and A(H5N1) is rapidly evolving. Strengthening collaborations at National, EU and Global levels would allow close monitoring of the AI situation, ultimately helping to increase preparedness. No human case was reported in the EU due to AIVs subtypes A(H5N1), A(H5N6), A(H7N9) and A(H9N2). Direct transmission of these viruses to humans has only been reported in areas, mainly in Asia and Egypt, with a substantial involvement of wild bird and/or poultry populations. It is suggested to improve the collection and reporting of exposure events of people to AI. © 2017 European Food Safety Authority, © European Centre for Disease Prevention and Control, and © European Union Reference Laboratory for Avian influenza EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. Keywords: avian influenza, HPAI/LPAI, monitoring, poultry, captive birds, wild birds, humans Requestor: European Commission Question number: EFSA-Q-2017-00229 Correspondence: [email protected] www.efsa.europa.eu/efsajournal EFSA Journal 2017;15(10):5018 Avian influenza overview October 2016–August 2017 Competing interests: In line with EFSA’s policy on declarations of interest, the following working group (WG) experts: Ian Brown, Paolo Mulatti, Krzysztof Smietanka and Christoph Staubach, have declared that they have current involvement in risk assessment activities at national level related to avian influenza, which constitutes a conflict of interest (with the mandate of the EFSA WG in hand. The CoIs have been waived and the waivers were adopted in accordance with Article 16(5) of the Decision of the Executive Director on Declarations of Interest of 31 July 2017 EFSA/LRA/DEC/02/2014, available at http://www.efsa.europa.eu/sites/default/files/corporate_publications/files/independencerule s2014.pdf. Pursuant to Article 16(7) of the above mentioned Decision, the concerned experts were allowed to take part in the discussions and in the drafting phase of the EFSA Scientific report on Avian influenza monitoring (Art. 31) - overview October 2016 – August 2017, and have not been allowed to be, or act as, a chairman, a vice-chairman or rapporteur of the WG. Acknowledgements: In addition to the listed authors, EFSA, ECDC and the EURL wish to thank the following: the hearing expert Thijs Kuiken for his support provided to this scientific output; Kaja Kaasik Aaslav, Epidemic Intelligence team at ECDC and Pasi Penttinen, Head of the Disease Programme Influenza and other Respiratory Viruses for the support provided to this scientific output; Members States representatives that provided the data on AI outbreaks and/or animal population for this scientificoutput: Austria (Andrea Hoeflechner-Poeltl, Eveline Wodak), Belgium (Philippe Houdart, Katie Vermeersch), Bulgaria (Aleksandra Miteva, Anna Zdravkova), Croatia (Zlatko Krovina, Tihana Miskic) Cyprus (Giorgos Krasias), the Czech Republic (Marie Vagnerov a), Denmark (Thorkild Bastholm, Torben Grubbe), Estonia (Kart€ Jaarma, Helen Prommik), Finland (Tiia Tuupanen), France (Lo€ıc Evain, Isabelle Guerry, Alexandra Troyano-Groux), Germany (Franz Conraths, Andrea Coßmann), Greece (Sokratis Perdikaris), Hungary (Zsofia Szepesine Kok any, Zsolt Terjek, Gabor Wyszoczky), Ireland (Stephanie Ronan, Eoin Ryan), Italy (Anna Sorgente), Latvia (Rudıte Varna), Lithuania (Paulius Busauskas), Luxembourg (Roger Gindt), Malta (Joseph Caruana), the Netherlands (Nina Berendsen, Dennis Bol, Geert Eleveld, Marcel Spierenburg), Poland (Edyta Swieton), Portugal (Yolanda Vaz), Romania (Ioana Neghirla, Alexandru Supeanu, Claudiu Stroe), Slovakia (Vilem Kopriva, Barbora Pavlikova), Slovenia (Aleksandra Hari), Spain (Ana Fernandez Martın, Ines Moreno), Sweden (Annica Wallen Norell), the United Kingdom (Adam Brouwer, Helen Roberts); Members States representatives that wrote the case reports on the AI secondary outbreaks and on the AI applied prevention and control measures, as reported in the Annex: Austria (Andrea Hoeflechner-Poeltl, Eveline Wodak), Belgium (Philippe Houdart, Ben edicte Lambrecht, Marjorie Piret, Mieke Steensels), Bulgaria (Aleksandra Miteva, Anna Zdravkova), the Czech Republic (Milada Dubska, Petr Satran, Marie Vagnerov a), Denmark (Pernille Dahl Nielsen, Stig Mellergaard), France (Mohamed Boukottaya, Anne Bronner, Alexandre Fediaevsky, Claire Guinat, Adeline Huneau-Salaun,€ Mathilde Paul), Greece (Sokratis Perdikaris), Hungary (Zsofia SzepesineK ok any, Gerda Pallai, Anna Luca Vecsei, Gabor Wyszoczky), Ireland (Eoin Ryan), Italy (Tiziano Dorotea, Lebana Bonfanti, Stefano Marangon, Paolo Mulatti), the Netherlands (Marcel Spierenburg), Romania (Nicolae Dragan, Ioana Neghirla, Alexandru Supeanu, Claudiu Stroe), the United Kingdom (Adam Brouwer, Ian Brown, Helen Roberts); Dominique Bicout and Arjan Stegeman for reviewing the document. Suggested citation: European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian influenza, Brown I, Mulatti P, Smietanka K, Staubach C, Willeberg P, Adlhoch C, Candiani D, Fabris C, Zancanaro G, Morgado J and Verdonck F, 2017. Scientific report on the avian influenza overview October 2016–August 2017. EFSA Journal 2017;15(10):5018, 101 pp. https://doi.org/10.2903/j.efsa.2017.5018 ISSN: 1831-4732 © 2017 European Food Safety Authority, © European Centre for Disease Prevention and Control, and © European Union Reference Laboratory for Avian influenza EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the Creative Commons Attribution-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. Figures from 1 to 16 © EURL; Figures 17, 19, 20, 22, 23 © Friedrich-Loeffler-Institut (FLI); Figures 18, 21, 26, 27, 28 © ECDC; Figures from C1 to C6 © EFSA The EFSA Journal is a publication of the European Food Safety Authority, an agency of the European Union. www.efsa.europa.eu/efsajournal 2 EFSA Journal 2017;15(10):5018 Avian influenza overview October 2016–August 2017 Table of contents Abstract................................................................................................................................................. 1 1. Introduction............................................................................................................................... 5 1.1. Background and Terms of Reference as provided by the requestor................................................. 5 1.2. Interpretation of the Terms of Reference...................................................................................... 6 2. Data.......................................................................................................................................... 6 2.1. Data on animals ......................................................................................................................... 6 2.1.1. Epidemiological data................................................................................................................... 6 2.1.2. AI prevention and control measures ............................................................................................ 7 2.2. Data on humans ........................................................................................................................ 7 3. Results ...................................................................................................................................... 8 3.1. Overview of HPAI and LPAI outbreaks in Europe between October 2016 and August 2017 (TOR 1 and TOR 2)...............................................................................................................................