Flavored Tobacco Products, Effective As of January 1, 2021
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Snus: the Original Reduced-Harm Tobacco Product
* Snus: the original reduced-harm tobacco product Although not risk-free independent evidence1,2 less harmful than cigarettes suggests it’s 95-99% Consumed orally by Used for centuries in placing under the lip Scandinavia* Smokeless, so lacks the Gentle heating during harmful toxicants and manufacture reduces the number carcinogens associated with of cancer-causing chemicals cigarette combustion that form in the tobacco Snus is currently banned across the EU, except in Sweden where it originates This is preventing millions of smokers from experiencing its potential harm reduction benefits NORWAY SWEDEN EU Average Thanks to the popularity of Sweden snus as a cigarette substitute, SWEDEN 24% 5% Sweden enjoys the lowest smoking rate in Europe (5%)3,4 Achieving a smoking rate of >5% is the goal of multiple European states by 2040.5 5% Thanks to snus, Sweden is decades ahead of the majority of its fellow members NORWAY Only 10% of Swedish snus 6 users also smoke cigarettes Snus is legal in More adults in Norway suggesting its potential ability Norway as it isn’t an use snus than smoke to fully ‘off-ramp’ adult smokers EU member state 12% vs. 11%10 Snus is typically used by more UK Royal College of men than women, although Physicians it’s becoming increasingly “In Norway, snus is popular with both genders7 Similar to Sweden, dual use of snus and associated with smoking cigarettes is low11 cessation”4 Primarily owing to snus, Sweden Average EU Sweden’s male adult tobacco consumption is actually slightly *Contemporary snus has evolved from an early precursor product, first used in Sweden over 300 years ago 26% 25% 3 1 higher than the EU average .. -
Preparation of Aspirin, Methyl Salicylate and Nylon Experiment #6
Preparation of Aspirin, Methyl Salicylate and Nylon Experiment #6 Objective: To observe the contrasts in appearance and odor of two different esters of salicylic acid, namely aspirin and methyl salicylate. The preparation of nylon will be demonstrated. Introduction Salicylic acid is a phenolic acid, indicating it has two functional groups on the benzene ring, an -OH group and a -COOH group. Aspirin and oil of wintergreen are esters of salicylic acid. Aspirin is the ester of salicylic acid and acetic acid (acetyl salicylic acid), whereas oil of wintergreen is the ester of salicylic acid and methanol (methyl salicylate). The chemical name for aspirin, acetyl salicylic acid, is not easily recognized as the name of an ester. However, the chemical name for oil of wintergreen, methyl salicylate, should readily be recognized as the name of an ester. In the preparation of aspirin the -OH group of salicylic acid reacts with the acetyl group of acetic acid or acetic anhydride to form acetyl salicylic acid. The formation of aspirin will proceed faster if acetic anhydride is used in place of acetic acid. However, acetic anhydride will hydrolyze in the presence of water to form acetic acid, slowing down the reaction. Hence, the reaction vessel must be very DRY to ensure a complete reaction. Sulfuric acid, H2SO4, is used as a dehydrating agent. The aspirin will be isolated by filtration and washed several times with ice cold deionized water to remove the water soluble impurities (acetic acid and sulfuric acid). Aspirin is quite insoluble in ice cold water, but is relatively soluble in warm water (1 g dissolves in 100 mL water at 37EC). -
Other Tobacco Products (OTP) Are Products Including Smokeless and “Non-Cigarette” Materials
Other tobacco products (OTP) are products including smokeless and “non-cigarette” materials. For more information on smoking and how to quit using tobacco products, check out our page on tobacco. A tobacco user may actually absorb more nicotine from chewing tobacco or snuff than they do from a cigarette (Mayo Clinic). The health consequences of smokeless tobacco use include oral, throat and pancreatic cancer, tooth loss, gum disease and increased risk of heart disease, heart attack and stroke. (American Cancer Society, “Smokeless Tobacco” 2010) Smokeless tobacco products contain at least 28 cancer-causing agents. The risk of certain types of cancer increases with smokeless tobacco: Esophageal cancer, oral cancer (cancer of the mouth, throat, cheek, gums, lips, tongue). Other Tobacco Products (OTP) Include: Chewing/Spit Tobacco A smokeless tobacco product consumed by placing a portion of the tobacco between the cheek and gum or upper lip teeth and chewing. Must be manually crushed with the teeth to release flavor and nicotine. Spitting is required to get rid of the unwanted juices. Loose Tobacco Loose (pipe) tobacco is made of cured and dried leaves; often a mix of various types of leaves (including spiced leaves), with sweeteners and flavorings added to create an "aromatic" flavor. The tobacco used resembles cigarette tobacco, but is more moist and cut more coarsely. Pipe smoke is usually held in the mouth and then exhaled without inhaling into the lungs. Blunt Wraps Blunt wraps are hollowed out tobacco leaf to be filled by the consumer with tobacco (or other drugs) and comes in different flavors. Flavors are added to create aromas and flavors. -
Snus: a Compelling Harm Reduction Alternative to Cigarettes Elizabeth Clarke1* , Keith Thompson2, Sarah Weaver1, Joseph Thompson1 and Grant O’Connell1
Clarke et al. Harm Reduction Journal (2019) 16:62 https://doi.org/10.1186/s12954-019-0335-1 REVIEW Open Access Snus: a compelling harm reduction alternative to cigarettes Elizabeth Clarke1* , Keith Thompson2, Sarah Weaver1, Joseph Thompson1 and Grant O’Connell1 Abstract Snus is an oral smokeless tobacco product which is usually placed behind the upper lip, either in a loose form or in portioned sachets, and is primarily used in Sweden and Norway. The purpose of this review is to examine the reported effects of snus use in relation to specified health effects, namely lung cancer, cardiovascular disease, pancreatic cancer, diabetes, oral cancer and non-neoplastic oral disease. The review also examines the harm reduction potential of snus as an alternative to cigarettes by comparing the prevalence of snus use and cigarette smoking, and the reported incidence of tobacco-related diseases across European Union countries. The scientific literature generally indicates that the use of snus is not a significant risk factor for developing lung cancer, cardiovascular disease, pancreatic cancer or oral cancer. Studies investigating snus use and diabetes have reported that high consumption of snus (estimated as being four or more cans per week) may be associated with a higher risk of developing diabetes or components of metabolic syndrome; however, overall results are not conclusive. Snus use is associated with the presence of non-neoplastic oral mucosal lesions which are reported to heal rapidly once use has stopped. The most recent Eurobarometer data from 2017 reported that Sweden had thelowestprevalenceofdailycigaretteuseintheEuropeanUnionat5%whilstdaily“oral tobacco” use was reported to be 20%. -
Focuson MOUTHRINSES
v16F_mouthrinsetable_Layout 1 3/28/14 11:04 AM Page 30 FOCUSonMOUTHRINSES This informative table provides details about the therapeutic and cosmetic mouthrinses currently available. Do patients truly understand how mouthrinses work? Some may think of them as “magic bullets” that will cure their dental ailments with just a swish and spit. Oral health professionals, however, know that this is not the case. Patients still need advice on the proper usage and selection of mouthrinses, and the best resource for mouthrinse information is you—their dental hygienist. As the dental team member whose focus is prevention, your knowledge of mouthrinses is paramount to providing excellent patient care. With so many different mouthrinses on the market today, keeping up to date on the prod- ucts available is challenging. This Dimensions of Dental Hygiene mouthrinse guide is intended to help you sort through both the therapeutic and cosmetic mouthrinse options. When consider- ing over-the-counter therapeutic mouthrinses, noting which products have received the American Dental Association’s Seal of Acceptance is also helpful, as they have been evaluated for safety and efficacy. We hope you find this guide useful when making product recommen- dations to patients who wish to add rinsing to their daily oral care regimens. —Jill Rethman, RDH, BA Editor in Chief Note: Mouthrinse manufacturers in the United States were invited to submit information for this table. This list includes those companies that responded to our request for information. There may be inadvertent -
Experiment 22 Synthesis of Aspirin and Oil of Wintergreen
Experiment 22 Synthesis of Aspirin and Oil of Wintergreen GOALS: In this two-week experiment the important area of organic chemistry will be illustrated by the preparation and characterization of two compounds. The usefulness of functional groups will be illustrated as well as the use of NMR, IR, and melting point in characterizing a product. The analysis will be done next week in Experiment 23. INTRODUCTION: Synthesis and use of organic compounds is an extremely important area of modern chemistry. Approximately half of all chemists work with organic chemicals. In everyday life, many if not most of the chemicals you come in contact with are organic chemicals. Examples include drugs, synthetic fabrics, paints, plastics, etc. Synthesis of Aspirin and Methyl Salicylate. The two compounds we will be preparing, aspirin (acetylsalicylic acid) and oil of wintergreen (methyl salicylate), are both organic esters. An ester is a compound that is formed when an acid (containing the –COOH group) reacts with an alcohol (a compound containing an –OH group). O O + C O C + O Eqn 1 R O H 1 H R2 R O R H H 1 2 ester water acid alcohol Here R1 and R2 represent groups such as CH3– or CH3CH2–. The reaction type shown above may be called a condensation reaction because the small molecule H2O is eliminated from the reactants while the remaining bits of the reactants condense together to give the main product. This reaction may also be called an esterification, since the product of the reaction is an ester, a compound containing the CO2R group (see chapter 20 for definitions of acids, esters, and alcohols). -
Invasive Plants Why They Must Go
Make informed choices at the nursery Instead of planting non-native rhododendrons, choose mountain laurel (Kalmia latifolia). Each of Periwinkle Pachysandra many delightful varieties has evergreen foliage and INVASIVE flowers in June. Lowbush blueberry Wintergreen Get rid of those privet hedges. Consider planting inkberry holly (Ilex glabra). It is evergreen, grows Groundcovers: know your friends in sandy soil and takes pruning well. If you would WHY THEY MUST GO and foes like your plants to produce berries for birds, then PLANTS you will need to Periwinkle (Vinca minor) plant both Still found in nurseries, this groundcover remains a female and popular choice. Unfortunately, it is not as innocent male shrubs as it looks. The aggressive plant can easily escape (one male for from your yard to a nearby forest and quickly take five female). over the forest floor. Remove those invasive burning bushes! Instead use Pachysandra (Pachysandra terminalis) huckleberries (Gaylussacia baccata). This small or Another common groundcover—and another medium-sized native shrub produces stunning hazard to the natural world. Has been found autumn color. growing in a few reservations on its own. Even In addition, you though it is less aggressive in our climate than (and local periwinkle, this is still an alien plant that does not birds) will add, but only subtracts from the environment. munch on the Instead of these aliens, consider the berries. † Sheep’s-Bit ¢ following lovely native plants for your groundcover: Aka Jasione montana looks pretty! However, this Instead of barberries, try winterberry holly (Ilex alien annual is rapidly invading southeastern Lowbush blueberries (Vaccinium angustifolium) verticillata). -
Aspirin a Curriculum Resource for Post-16 Chemistry and Science Courses
Aspirin A curriculum resource for post-16 chemistry and science courses 1 Aspirin (2nd edition) Compiled by David Lewis Edited by Colin Osborne and Maria Pack Designed by Imogen Bertin and Sara Roberts First published by the Royal Society of Chemistry in 1998 Second edition published by the Royal Society of Chemistry in 2003 Printed by the Royal Society of Chemistry Copyright © Royal Society of Chemistry 2003 Registered charity No. 207890 Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the UK Copyright Designs and Patents Act, 1988, this publication may not be reproduced, stored, or transmitted, in any form or by any means, without the prior permission in writing of the publishers, or in the case of reprographic reproduction, only in accordance with the terms of the licences issued by the Copyright Licensing Agency in the UK, or in accordance with the terms of licences issued by the appropriate Reproduction Rights Organisation outside the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the Royal Society of Chemistry at the London address printed on this page. Notice to all UK Educational Institutions. The material in this book may be reproduced by photocopying for distribution and use by students within the purchasing institution providing no more than 50% of the work is reproduced in this way for any one purpose. Tutors wishing to reproduce material beyond this limit or to reproduce the work by other means such as electronic should first seek the permission of the Society. -
Taking Herbal Medications Before Surgery
Taking Herbal Medications before Surgery The American Society of Anaesthesiologists (ASA) is cautioning those who use herbal medications to stop taking these “natural” products 1 week prior to having a surgery. Recent findings disclose that seven out of 10 herbal medicine users never tell their physicians about the herbal products they are taking. Most believe that since the products are “natural” they must be safe. Just because a medicine is called “natural” or “herbal” does not mean it is harmless or completely safe. Many of these products are quite potent and can be dangerous, especially if the patient’s anaesthetist or surgeon does not know that the patient is taking them. A number of anaesthetists have reported significant changes in heart rate or blood pressure in some patients who have been taking herbal medications. These herbal products include: Baikal skullcap root (Scutellaria baicalensis) Herb or dietary supplement Bilberry fruit (Vaccinium myrtillus) Ginkgo leaves (Ginkgo biloba) Black currant seed oil (Ribes nigrum) Ginseng root (Panax ginseng) Bladderwrack (Fucus vesiculosus) Green tea (Camellia sinensis) Borage seed oil (Borago officinalis) Hawthorn leaf and flower (Crataegus oxyacantha, Crataegus monogyna) Bromelain from pineapple fruit and stem (Ananas comosus) Horse chestnut bark (Aesculus hippocastanum) Cayenne fruit (Capsicum frutescens) Huang qi (Astragalus membranaceus) Celery plant (Apium graveolens) Kava kava root (Piper methysticum) Chamomile, German flowers (Matricaria recutita) Licorice root (Glycyrrhiza glabra) Clove oil (Syzygium aromaticum) Omega 3 Coleus roots (Coleus forskohlii) Papain from papaya leaves and unripe fruit (Carica papaya) Da huang, Chinese rhubarb root (Rheum palmatum) Pau d’arco bark (Tabebuia avellanedae) Dan shen root (Salvia miltiorrhiza) Reishi mushrooms (Ganoderma lucidum) Dandelion root (Taraxacum officinale) St. -
Chemistry Education Experiment Manual Carbon
Spins lveTM Benchtop NMR Spectrometer Chemistry Education Experiment Manual Carbon Contents Chapter 1: Introduction to NMR Chapter 2: How to interpret an NMR spectrum Chapter 3: How to operate the Spinsolve Experiment 1: Isomers Identification of isomers Distinguishing between isomers Experiment 2: Composition of some common household products Experiment 3: Separation of acidic, basic and neutral compounds Experiment 4: Measuring lipophilicity with NMR Experiment 5: Quantitative NMR Experiment 6: Preparation and characterisation of metal acetylacetonate complexes Experiment 7: Synthesis of aspirin Experiment 8: Synthesis of p-nitroaniline via a multistep sequence Experiment 9: Synthesis and reactions of Ferrocene Experiment 10: Reaction monitoring With a software upgrade to 2D capability Experiment 11: Aldol condensation Experiment 12: Reactions of Ferrocene derivatives With a hardware upgrade to 13C capability Experiment 13: Identification of an alcohol using 13C NMR and DEPT Experiment 7: Synthesis of Aspirin Introduction Salicylic acid is contained in the extract of willow bark trees and was used for hundreds of years to relieve pain and treat fevers. Unfortunately, salicylic acid has two acidic functional groups – the phenol group and the carboxylic acid group. This gives salicylic acid some unpleasant side effects such as irritation to the mouth, oesophagus and stomach and can cause haemorrhaging of the stomach lining. Fortunately, in 1890, Hoffman of the Bayer Company in Germany found a way to mask the irritating phenol group with an ester to produce aspirin. Aspirin is the common name for acetylsalicylic acid, which is widely used as an effective pain killer and fever reducer. About 35,000 metric tonnes of aspirin, enough for 100 billion tablets, is produced and consumed every year. -
Tobacco Use Behaviors for Swedish Snus and US Smokeless Tobacco
Tobacco Use Behaviors for Swedish Snus and US Smokeless Tobacco Prepared for: Swedish Match, Stockholm, Sweden and Swedish Match North America, Richmond, Virginia Prepared by: ENVIRON International Corporation Arlington, Virginia Date: May 2013 Project Number: 2418132C Snus and US Smokeless Tobacco Contents Page Executive Summary 1 1 Introduction 6 1.1 Background 6 1.2 Literature search and methods 8 2 Temporal, Geographic and Demographic Patterns of Smokeless Tobacco Use. 10 2.1 Scandinavia 10 2.1.1 Current and Historical Temporal Trends of Swedish Snus 10 2.1.2 Geographic variations in snus use 12 2.1.3 Age and gender 12 2.1.4 Socioeconomic and occupational variations in snus 14 2.1.5 Other individual level characteristics related to snus 15 2.1.6 Exposure estimates: frequency, amount and duration of snus 15 2.2 United States 17 2.2.1 Temporal trends 18 2.2.2 Geographic variations in smokeless tobacco use 19 2.2.3 Age and gender 20 2.2.4 Race/ethnicity 21 2.2.5 Socioeconomic and occupational variations in smokeless tobacco use 22 2.2.6 Other individual level characteristics related to smokeless tobacco use 23 2.2.7 Exposure estimates: frequency, amount and duration of smokeless tobacco use 23 2.3 Summary and Conclusions 23 3 Relationship of Smokeless Tobacco to Smoking 25 3.1 Population-level transitioning between tobacco products 26 3.1.1 Scandinavia 26 3.1.2 United States 27 3.2 Individual-level transitioning between tobacco products: Gateway and transitioning from smokeless tobacco to cigarettes 27 3.2.1 Scandinavia 28 3.2.2 United States 31 3.3 Transitioning from cigarettes to smokeless tobacco and smoking cessation 35 3.3.1 Scandinavia 36 3.3.2 United States 41 3.4 Snus/Smokeless Tobacco Initiation 45 3.4.1 Scandinavia 45 3.4.2 United States 46 3.5 Dual Use 47 3.5.1 Scandinavia 47 3.5.2 United States 52 4 Summary and Conclusions 57 Contents i ENVIRON Snus and US Smokeless Tobacco 5 References 60 List of Tables Table 1: Recent Patterns of Snus Use in Sweden (Digard et al. -
Surveillance and Characterisation of Online Tobacco and E-Cigarette Advertising Amanda Richardson,1,2 Ollie Ganz,1 Donna Vallone1,2
Research paper Tob Control: first published as 10.1136/tobaccocontrol-2013-051246 on 14 February 2014. Downloaded from Tobacco on the web: surveillance and characterisation of online tobacco and e-cigarette advertising Amanda Richardson,1,2 Ollie Ganz,1 Donna Vallone1,2 ▸ Additional material is ABSTRACT Advertising influences the initiation and contin- published online only. To view Background Despite the internet’s broad reach and ued use of tobacco products among both youth and please visit the journal online fl 9–12 (http://dx.doi.org/10.1136/ potential to in uence consumer behaviour, there has adults. Given the restrictions on tobacco adver- tobaccocontrol-2013-051246). been little examination of the volume, characteristics, tising in the USA arising from the Master and target audience of online tobacco and e-cigarette Settlement Agreement,13 14 which banned tobacco 1Department of Research, Legacy, Washington, DC, USA advertisements. advertising from broadcast media, and the restric- 2Department of Health, Methods A full-service advertising firm was used to tions set forth restricting advertising to youth in Behavior and Society, Johns collect all online banner/video advertisements occurring the Family Smoking Prevention and Tobacco Hopkins Bloomberg School of in the USA and Canada between 1 April 2012 and 1 Control Act15 16 as well as the almost complete Public Health, Baltimore, April 2013. The advertisement and associated meta-data restrictions on advertising set forth in Tobacco Act Maryland, USA – on brand, date range observed, first market, and spend of Canada and its 2009 Amendment,17 19 online Correspondence to were downloaded and summarised. Characteristics and advertising has allowed the tobacco industry to Dr Amanda Richardson, themes of advertisements, as well as topic area and promote their products in a space that has broad Department of Research, target demographics of websites on which reach and is largely unregulated.20 This may, in Legacy, 660 Pennsylvania Avenue SE, Washington, DC advertisements appeared, were also examined.