A Powerful Force U Researchers Push the Limits of Medicine’S Strongest Magnets

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A powerful force U researchers push the limits of medicine’s strongest magnets

Winter 2009 Invention thrives where medicine and engineering intersect Dynamic duo combats health disparities Public health leader puts environmental toxins on his hit list WINTER 2009 Contents

DEAR FRIENDS,

Medical advances don’t happen state-of-the-art imaging technology, in tidy compartments like special- and the CMRR, in turn, can benefit ties or academic divisions. They from their expertise. cross boundaries, occurring, for Collaboration also is fueling inven- example, where physicists connect tion in the Institute for Engineering with oncologists, neurologists, in Medicine (IEM), established in and engineers. 2007 by the Medical School and the At the University’s Center for Mag- Institute of Technology. As you’ll netic Resonance Research (CMRR), read in our story on page 8, the IEM’s recognized as one of the world’s best 118 faculty members represent more imaging labs, scientists are making than 30 academic disciplines. important discoveries in diseases as Meanwhile, medical students diverse as diabetes, breast cancer, Suzanne Garber and Ngozika Okoye, ataxia, and schizophrenia. And, led profiled on page 14, are working to by Kamil Ugurbil, Ph.D., a chemical eliminate boundaries that result in physicist and professor in the Depart- 2 8 14 lower medical standards for people ments of Radiology, Neuroscience, of color and underserved communi- and Medicine, they’re expanding the ties. As copresidents of our Student boundaries of imaging science itself National Medical Association chapter, (see our cover story). they are building alliances that benefit DEPARTMENTS Now undergoing a major expansion our patients and communities. Features in the University’s emerging Bio- Medical School News In today’s economic climate, 18 medical Discovery District, the 2 A POWERFUL FORCE such collaboration is more crucial CMRR will be obtaining a 16.4 Tesla The Center for Magnetic Resonance Research, soon to house the world’s 2 3 Alumni Connections than ever, and you will find it at the magnet, the world’s strongest. And strongest magnet, is pushing the technology’s limits heart of our Medical School’s 2 4 Alumni Spotlight: it will be linked to neighboring labs success stories. Creating a healthier in such fields as neuroscience, 8 BODY MECHANICS world for children cardiovascular medicine, and stem Deborah E. Powell, M.D. Biomedical invention thrives at the University’s Institute for Engineering cell research so scientists in those Dean, University of Minnesota Medical School in Medicine, where scientists are fi nding better ways to tune up the 30 A Look Back: MMF turns 70 areas have easy access to the McKnight Presidential Leadership Chair ultimate machine ON THE WEB 14 ‘COMPLEMENTARY’ MEDICINE A yin-yang dynamic makes the University’s Student National Medical Find Web-exclusive content Association copresidents more effective as they combat health disparities in the online version of the The mission of the Minnesota Medical Foundation is to improve the quality of life for Medical Bulletin. Go to: the people of Minnesota, the nation, and the world by supporting the advancement www.mmf.umn.edu/bulletin. of health-related education, research, and service at the University of Minnesota. ON THE COVER RESOLVING TO GO GREEN THIS YEAR? E-mail us at [email protected] to receive the Photo of Center for Magnetic Medical Bulletin by e-mail instead of as a paper copy. Resonance Research director Kamil Ugurbil, Ph.D., by Tim Rummelhoff A powerful force The Center for Magnetic Resonance Research, soon to house the world’s strongest magnet, is pushing the technology’s limits ome scientists make strides in biomedical research by acquiring state-of-the-art S equipment and then using it to answer questions about living systems. “Good research can be done in that fashion,” says Kamil Ugurbil, Ph.D., director of the University of Minnesota’s Center for Magnetic Resonance Research (CMRR).

But Ugurbil takes a different approach. A chemical physicist by training, he has always veered away from using new machines straight out of the box. Instead, he likes to develop novel technologies and pushes them beyond what anyone ever imagined they could do. Even at points when other experts in the ﬁeld believed magnetic resonance tools had reached their limits, Ugurbil and his colleagues have persisted, extending the capabilities of the magnets and ﬁnding new applications for them.

He puts it this way: “We’re excited when we can get information that is beyond the bread and butter of the technology.” That desire to test the untapped potential of new high-ﬁeld magnets has placed the CMRR among world leaders in imaging. It’s also stretched every parameter of the discipline.

Today the burgeoning center, which Ugurbil has led since 1991, has 21 faculty members and six high-ﬁeld magnets, with an additional “ultra-high-ﬁeld” magnet on the way. As the latest construction project in the University’s developing research park, called the Biomedical Discovery District, the CMRR building is undergoing a renovation and large-scale expansion expected to be completed by fall 2010. A $53 million budget, provided in part by the state, will add approximately 65,000 square feet for new research and clinical studies.

2 MEDICAL BULLETIN WINTER 2009 M EDICAL BULLETIN WINTER 2009 3 The expanded building will house a magnet with a bore capable of holding Acquiring that magnet involved a leap

ELHOFF new magnet that will be the highest small animals. Ugurbil’s group began of faith, Ugurbil acknowledges today. MM

RU ﬁeld ever attained for human studies. to think about studying intact living Even industry members had aban- M (The magnets are referred to by the organisms with the high-ﬁeld magnet. doned the idea of developing a 4 Tesla O: TI T

PHO strength of their magnetic ﬁelds; magnet to study humans; the images it “We had the basis to believe we could typical magnetic resonance imaging produced were less clear than a stan- succeed in that area,” Ugurbil says. The [MRI] machines used for hospital dard magnetic resonance image. But magnet was so new that the group had diagnoses have a 1.5 Tesla magnet.) Ugurbil believed the magnet’s higher to develop its own software applications And an astounding 16.4 Tesla magnet sensitivity offered an opportunity to to use it. But as they succeeded in currently being installed in the reno- map brain activity, and his group attaining useful images of rat organs, vated section of the building will be developed strategies to address some they became intrigued by a bigger the largest magnet in the country; the of the confounding factors. challenge: applying the technology only other one of its kind is in Europe. to humans. He and his team forged ahead with These technologies are so new that plans to use the magnet to study even Ugurbil isn’t certain what they’ll It turns out that humans are compli- increased oxygenation in areas of the be capable of revealing, although his cated subjects for MR studies. Both

brain. In collaboration with Bell Labo- ELHOFF team’s track record with new tools building the high-ﬁeld magnet to

ratories, they mapped active neuronal UMM suggests that remarkable discoveries R accommodate a person and creating M I

regions of the brain in living subjects, T Brain scans performed by cancer researcher are on the horizon. an image as the magnetic fields Michael Garwood, Ph.D., in the late 1980s a technique known as functional increase become more difficult. In the PHOTO: showed the advantage of high-resolution A paradigm shift imaging or fMRI. At the same time, late 1980s, no groups anywhere were 4 Tesla images over 1 or 1.5 Tesla, then Garwood demonstrated that, contrary Center for Magnetic Resonance Research director Kamil Ugurbil, Ph.D., develops novel imaging The changing geographic location of having success with increased field thought to be the optimal magnetic field technologies and pushes the boundaries of what they can do. magnetic resonance (MR) research on to expectations at the time, it was for research and clinical use. strength for human imaging. the University campus tells the story feasible to obtain beautiful anatomical images of the human brain at 4 Tesla. about the rising promise and promi- “It was accepted at the time that 1 to The 7 Tesla magnet the group acquired For University 1.5 [Tesla] would be the optimal mag- nence of Ugurbil’s group. When Ugurbil “The very first experiments we did on in 1999 was the world’s first of its kind netic field for doing MR research and researchers from a arrived at the University of Minnesota the 4 Tesla were great successes,” developed for human studies. A recent- for clinical diagnoses,” says Michael in 1978 after working at Bell Laboratories recalls Ugurbil. They offered a para- ly acquired 9.4 Tesla brain imaging variety of disciplines, and then at Columbia University, his Garwood, Ph.D., associate director of system — another world first — is now digm shift in how MR could be used. the collection of lab was housed with the Gray Fresh- the CMRR, who was then a postdoc in place as well. water Biological Institute, located at the University. At the time, along with the 4 Tesla magnets and the machine, the group had two magnets Focused on the brain on the St. Paul campus, far from the Higher and higher University’s medical center. (The insti- for in vivo animal studies and continued For University researchers from a in-house expertise But keen on improving the magnets’ tute is no longer part of the University.) to advance MR spectroscopy. But with variety of disciplines, the collection of at the Center for resolution and sensitivity, Ugurbil little room to expand, and with an magnets and the in-house expertise at At Bell Labs, Ugurbil had written papers linked his group with the Medical interest in attaining new magnets, in the Center for Magnetic Resonance Magnetic Resonance about applying MR spectroscopy to School’s radiology department. Bill 1998 the CMRR moved into its current Research offer unparalleled opportuni- Research offer cellular metabolism that would shortly Thompson, M.D., the department chair building, a low, brightly lit structure ties to study diseases. With funding become classics. At the University, he at the time and an ardent supporter of that helps anchor the emerging from the National Institute of Mental unparalleled intended to continue exploring what advancing MR research — aided by research park on the north side of the Health, University psychiatry professor opportunities to magnetic resonance technology could David Brown, M.D., who was dean of University’s new TCF Bank Stadium. Kelvin Lim, M.D., for example, has do with cells and even intact organs. the Medical School — enabled Ugurbil collected magnetic resonance images study diseases. to acquire one of the first industry- Over the next decade, the group But then, with a program project grant of anatomical differences in the brains To view high-resolution built 4 Tesla systems. The instrument acquired an array of new magnets for from the National Institutes of Health of people with schizophrenia. In body scans and hear experts was set up in the CMRR’s first home, a both animal and human research, and and matching funds from the Univer- particular, he’s looking at the gray describe the technology and its building near the University’s medical the building underwent three separate applications, go to www.mmf. sity’s administration, the Freshwater matter deficit that occurs early during center on East River Road. renovations to accommodate them. edu/mb/powerful.cfm. Biological Institute obtained a 4.7 Tesla the disease course.

4 MEDICAL BULLETIN WINTER 2009 MEDICAL BULLETIN WINTER 2009 5 At the same time, he’s been able to “It’s been shown that if you can inter- measure changes in brain activity vene early on in the disease, you can using fMRI. The studies so far have reverse the changes and rescue the looked at humans in the CMRR’s cells before they die,” Öz explains. 3 Tesla magnet, but Lim hopes to What’s more, better understanding develop techniques to use the center’s of the neurochemistry may reveal even higher-resolution 9.4 Tesla magnet commonalities among a range of to do magnetic resonance spectros- neurodegenerative disorders, providing copy, which will offer a glimpse information about other diseases like of specific neurochemical changes in Alzheimer’s and Parkinson’s. schizophrenic patients. A new tool for evaluating Other projects delve into different breast tumors “Access to this type of hardware gives aspects of various disease processes, us a tremendous advantage here,” he from a study taking place with the Biochemist Gülin Öz, Ph.D., is using magnetic resonance spectroscopy to track chemical precursors to MAGNETIC RESONANCE IMAGING has long been studied as a noninva- says. Ultimately, these refined views Mayo Clinic that looks at the amyloid spinocerebellar ataxia with the hopes of disrupting of the brain may reveal subcategories plaques that form in people with sive tool for detecting breast tumors, and in fact, has nearly 100 percent the process before the condition causes irreversible sensitivity for detecting breast cancer. But the technology, which offers of schizophrenia, each with its own Alzheimer’s disease (researchers at the damage to the brain. telling views of a tumor’s morphology, margins, and associated blood unique characteristics. “One of my CMRR were the first ever to visualize vessels, still can’t always discern whether the lump is benign or malignant. goals is to get to the point,” Lim says, those plaques in living organisms) to A decade ago, some groups began looking at lumps using magnetic “where we have important biomarkers a collaboration with University of What’s clear is that the work Ugurbil Better understanding resonance spectroscopy, which can detect choline, a chemical that [for each subcategory] that can help us Minnesota diabetes researcher Elizabeth began 25 years ago has created an increases in the presence of a cancerous tumor. Then, in 1999, oncologist guide treatment.” “Betsy” Seaquist, M.D., who is investi- unprecedented resource. “There’s no of the neurochemistry Douglas Yee, M.D., director of the Masonic Cancer Center, University of gating how diabetic “sugar crashes” setup quite like the one we have here, may reveal commonal- Down the hall, CMRR biochemist Gülin Minnesota, and Center for Magnetic Resonance Research (CMRR) associ- affect metabolism in the brain. in scope of instrumentation and Öz, Ph.D., is studying the effects on the ities among a range of ate director Michael Garwood, Ph.D., became curious about using MR quality of leadership,” states Charles brain of a mutant gene that causes a A $7.9 million grant from the National spectroscopy from another angle: Could it be used to quantify the Moldow, M.D., vice dean for research neurodegenerative neurodegenerative disease known as Institutes of Health in 2006 helps presence of choline and could the amount it revealed determine whether and operations in the Medical School. a therapy was working? spinocerebellar ataxia. In humans, ensure that the CMRR’s state-of-the- disorders, providing where her MR investigations began, the art equipment is available to these The construction planned for the What the researchers found using a 4 Tesla research magnet was that information about spectroscopy could pinpoint the choline levels, says Patrick Bolan, Ph.D., genetic condition eventually results in and other neurosciences researchers research park around the CMRR will who joined the project as a graduate student a decade ago and continues irreversible damage to the cerebellum, across the University. situate the building among other other diseases like to advance this line of research as a CMRR faculty member today. Even causing movement problems like loss medical research as it’s never been An unprecedented resource Alzheimer’s and further, their experiments determined, a tumor that was responding to an of balance and coordination as well as positioned before, notes Kevin Ross, effective drug would show a drop in choline within a single day, and the awkward gait. But as she sought more Now, with sights set on bringing in new capital planning project manager for the Parkinson’s. technology was sensitive enough to detect the decrease. specific and controlled biochemical ultra-high-field magnets, the CMRR expansion. New skyways linking the That pilot study, published in 2004 in the journal Radiology, has led to information about what was happening faces new research possibilities — building to its neighbors will connect it a multicenter trial now under way using MR spectroscopy to get a glimpse to the cells, Öz redirected her MR and new challenges. Even though the with labs in such fields as neuroscience, of how tumors are responding to chemotherapy one day after it’s given. spectroscopy studies to look at the 16.4 Tesla magnet for studying animals immunology, and stem cell research. One long-term challenge will be whether the highly technical spectroscopy brains of mice that have the mutation. is powerful enough to visualize a Until now, the building has “stood very can be implemented with standard magnets for easy, widespread use in a process as minute as the development much isolated from campus, kind of on In collaboration with ataxia expert clinical setting, but the potential benefits of the technology seem clear. of a rat embryo, it may take years to the outskirts,” says Ross. “Now, when Harry Orr, Ph.D., in the Department “If you can actually determine whether a drug works after a day, you develop the methodologies that can the CMRR expansion is completed, it can switch drugs or try new ones without exposing a patient to a long- of Laboratory Medicine and Pathology, take full advantage of the magnet’s will be in the heart of a state-of-the-art term course [of chemotherapy]. There are no other tools like this one in who provided a mouse model for the capabilities. In typical style, Ugurbil research community.” M|B oncology right now,” Bolan says. “It could have a very big impact.” disease, Öz is conducting research to pushed to acquire the tools to get that By KATE LEDGER, a free-lance writer living in the pinpoint chemical precursors to the work started. (The project received devastating structural changes that Twin Cities who specializes in topics related to University support as well as $2 mil- medicine and research. the neurons undergo. lion from the NIH.)

6 MEDICAL BULLETIN WINTER 2009 MEDICAL BULLETIN WINTER 2009 7 Biomedical invention thrives at the University’s Institute for Engineering in Medicine, where scientists are ﬁ nding better ways to tune up the ultimate machine

Body mechanics

constant hum fills the air at the University of Minnesota’s Medical Devices Center. It’s not the whir of high-tech equipment, but the talk of the three engineers and one medical student taking part in the 2008–09 Medical Devices Fellows Program, and the energy they’re generating makes it clear why the University is gaining renown as a fertile ground for collaborations between physicians and engineers.

MEDICAL BULLETIN WINTER 2009 9 STREBLE SCOT T

PHOTO: voice communication with surgical have the local industry to tap as Feet in two worlds suites during medical procedures. One our research gets to the point of WEWERK A of the center’s goals, according to its commercialization.” WHEN BRYAN ARMITAGE enrolled in director, Art Erdman, Ph.D., is to make the University of Minnesota Medical School, STEVE The IEM’s mission focuses on interdis-

it easier for engineers and physicians to his background made him stand out. As PHOTO: ciplinary research that applies engi- collaborate in creating innovative an undergraduate at Cornell University in neering to medical problems and the medical solutions. Ithaca, New York, he earned a dual degree in improvement of medical care. Bolstered chemical engineering and biology, and soon “I’ve been impressed by the interest by donations from individuals and corp- after graduation, he interned for a medical in this program from the medical orations, it supports centers devoted to the device manufacturer. Later, he spent five device industry and the University,” study of medical devices and cardiovascular years working as an engineer for a company Jeffrey McCullough, M.D., director of the Institute for Engineering in Medicine, is bringing says Bryan Rolfes, the medical student repair, and it funds a wide variety of that made orthopaedic medical devices. together engineers and physicians to solve complex medical problems. among the fellows, who previously research that crosses traditional “When I had conversations with the worked for a product innovation fi rm academic boundaries. doctors involved with the company as well and has been building and fi xing as the machinists on the floor, I felt like I “Minnesota is uniquely positioned, There’s still a lot In the early weeks of their program — things since his childhood on a could speak multiple languages,” he says. with major strengths in biomedical one of many under the umbrella of the Nebraska farm. “The human body As a medical student, he continued his of mystery in the engineering research and develop- University’s Institute for Engineering is the ultimate machine,” he says. involvement with medical devices, assisting Bryan Armitage will graduate ment,” says John Bischof, Ph.D., the mechanics of the in Medicine — f e l l o w s Benjamin “There’s still a lot of mystery in the a start-up company that produces in May after completing IEM’s associate director of research. the University’s 5-year Arcand, Ph.D., Joseph Hale, Ph.D., Nikhil mechanics of the body, and it is fasci- knee braces. body, and it is “We have talent, resources, and a M.D./M.S. Dual Degree Murdeshwar, Ph.D., and Bryan Rolfes Armitage hoped not to abandon these nating to try to go where nobody’s ever Program in Medicine and unique environment that includes interests as his medical studies grew more fascinating to try to bulldozed through a crash course on gone before.” Biomedical Engineering. not only strong schools of engineering intellectual property, entrepreneur- demanding. “For me, the what of medicine go where nobody’s Interdisciplinary research and medicine and an academic ship, creativity, fund-raising, and isn’t as interesting as the why,” he says. health center, but also local industry ever gone before. coaching in business networking. That thrill of discovery, accompanied “Some medical students may be content simply knowing that athero- unmatched in the medical device area.” Affectionately called Boot Camp, it was by medical and engineering rigor and sclerotic plaques happen in arteries, for instance, but I want to know – Bryan Rolfes, medical student why. The answer is related to how rivers flow and other issues of a nonstop parade of lectures, demon- a disciplined approach to commercial In fact, medical technology businesses and medical devices fellow fluid dynamics.” strations, tours, trips to the operating possibilities, infuses the collaborations play a big part in advancing the IEM. His background and way of thinking made Armitage a perfect candidate room, and discussions. that thrive in the Institute for Engi- Businesspeople lead workshops and for the University of Minnesota’s M.D./M.S. Dual Degree Program in neering in Medicine (IEM). Established events, mentor students who make up Next, they began documenting Medicine and Biomedical Engineering, offered in cooperation with the in the summer of 2007 on the founda- the next generation of device engineers hundreds of medical needs that new Biomedical Engineering Department. Launched by a $1 million endow- tions of the Medical School’s former and inventor-clinicians, and ultimately medical devices and technology might ment gift from Medical School alumnus Scott Augustine, M.D., and his Biomedical Engineering Institute, the hire them. Much of the equipment in satisfy. And fi nally, by the end of the wife, Susan, the program lets students complete both an M.D. and M.S. IEM is jointly sponsored by the Medical the Medical Devices Center arrives academic year, the fellows will have in biomedical engineering in five years. Armitage completed his M.S. in School and the Institute of Technology. through corporate donations. identifi ed about 20 needs with the most fall 2008 and will earn his M.D. in May. Its 118 faculty members represent attainable and commercially attractive His biomedical engineering and medical studies have frequently illu- more than 30 academic disciplines. In turn, the IEM participates in educa- minated one another. When he studied clinical problems with bones in solutions, created prototypes of the tional opportunities offered by the medical school, he could refer to what he had learned about artificial devices that would meet those needs, “We’re capitalizing on the synergies Department of Integrative Biology and bones as a biomedical engineer. In turn, his clinical experiences helped and applied for provisional patents. and applications of engineering to Physiology aimed at people working in him understand why medical devices do or don’t work. “I could see things medical problems to help patients,” the medical device industry, including They accomplish most of this work a little differently than my fellow medical students,” says Armitage, who says IEM director Jeffrey McCullough, a cardiac physiology and anatomy in the Medical Devices Center, which hopes to go into orthopaedics after completing medical school. M.D. “You need this institute to have class and a cadaver lab available for houses laboratories for mechanical feet in both engineering and medicine. dissections. Because many engineers prototyping, computer-aided design At the University, the Institute of in the medical industry have never and precision instruments, electronics Technology and the Medical School thoroughly studied anatomy — much fabrication, assembly and molding, are right across Washington Avenue less worked with cadavers — these and SimPortal technology that allows from each other. We can bring together courses allow them to pick up crucial direct three-dimensional viewing and engineers and physicians, and we

10 MEDICAL BULLETIN WINTER 2009 MEDICAL BULLETIN WINTER 2009 11 STREBLE SCOT T

knowledge as they gain an under- using new technology that offers a PHOTO: It’s possible to look standing of the University and its solution, What If? funds provide seed JOHNSON strengths in engineering and medicine. money of $5,000 to $15,000 to get the into the future of the NANCY project going. It often allows the medical industry by What if?

PHOTO: researchers to accumulate enough data examining the projects It’s possible to look into the future of to fi le provisional patent applications the medical industry by examining the and attract interest from the NIH, that the IEM funds. projects that the IEM funds: a diverse NASA, and other major funders. range of multidisciplinary collaborations, most involving engineering “We support the ‘eureka’ of the idea students and medical staff and faculty. itself,” Bischoff says. “A clinician and Interest group grants of $5,000, for an engineer may need to explore example, are designed to get research- how a prospective medical device ers talking and hatching collaborations. would change medicine and affect the These nascent discussions might lead special need they have identifi ed. It’s to a concrete project, or they might speculative — a forward-thinking and Medical Devices Fellows Program director Marie Johnson, Ph.D., says she’s looking for “tinkerers.” fl icker out. progressive way of funding ideas.”

Larger grants of $100,000 or more go In the What If? program’s fi rst two years, the IEM awarded $170,000 to projects already carrying signifi cant Collaborators After their selection, this year’s four To watch a video about the momentum, such as those close to to 18 project teams. Three of those intersection of medicine, engi- Marie Johnson, Ph.D., director of the fellows took the Myers-Briggs Type projects progressed to NIH grant neering, and business, go to obtaining major support from the Indicator assessment, and three applications for more research, two Medical Devices Fellows Program, www.mmf.umn.edu/mb/body.cfm. National Institutes of Health (NIH) or emerged as INTJs, an uncommon produced medical device prototypes, knows exactly the kind of person who other funding sources in such areas personality type distinctive for its two (an absorbable nasal stapler and thrives in the interdisciplinary devel- Medical devices fellow Benjamin as multimodal biomedical imaging drive to make sense of the world, a bioartifi cial arachnoid shunt to opment of medical devices at the IEM. Arcand, Ph.D., shapes a piece of (combining various brain imaging design systems, and fi nd out why prevent swelling and fl uid buildup in That type herself, she invented a material for a new device while techniques to enhance their results), things work. That sounds like a perfect the brain) resulted in provisional computerized stethoscope to noninva- Joseph Hale, Ph.D. (foreground), cell-based cardiac regeneration and summary of the University’s medical looks on. Bryan Rolfes and Nikhil patents, and one sparked a clinical sively detect coronary disease, and she repair, and medical device design. inventors. Murdeshwar, Ph.D. (background), trial now under way. Currently funded improved her tiny offi ce in the Shep- make a model of another mechan- In addition, the Medical Devices Center projects include: herd Labs by building a platform that Erdman, the Medical Devices Center ical part. gives its own grants to member groups supports her desk and equipment director, believes medical-engineering An implantable electrical sensing that are conducting research on new while providing ingeniously designed inventors have other qualities that and stimulating catheter that also medical devices. Its recently funded storage space underneath. contribute to the success of such projects include efforts to develop delivers drugs, being developed by “Tinkerers, that’s who we’re looking collaborations at the University: “They computer-assisted screening for retinal a team of surgeons and a biomedi- for,” she declares. “They identify usually have a combination of a desire disease, to facilitate the design of cal engineer; unmet medical needs and fi nd solu- to improve health care — t h e y don’t medical devices in virtual reality, to A system to monitor hand disinfec- tions. But they don’t rogue-invent say the status quo is fi ne — w i t h an create new magnetic heating devices tion compliance, in development by devices that no one wants or will pay entrepreneurial spirit that says, ‘Let’s for cancer therapy and drug and investigators from the departments M|B for. They hear the clear voice of the make this work.’” stem-cell delivery, and to produce a of Electrical and Computer Engi- customer.” Johnson, who has com- robotic scrub nurse that surgeons can neering, and Medicine, including the By JACK EL-HAI, author of The Lobotomist: A Maverick Medical pleted three postdoctoral-level fellow- use to retrieve tools and supplies in Division of Infectious Diseases; and Genius and His Tragic Quest to Rid the World of Mental Illness. ships, scrutinizes the many applicants the operating room. A cooling device to aid in the for the fellows program by putting top The IEM also supports innovative treatment of head and neck inju- contenders through an eight-hour investigations with What If? grants. ries, under investigation by a interview that includes mock brain- When IEM members pinpoint a medi- neurologist and a mechanical storming sessions. cal need and settle upon an approach engineer.

12 MEDICAL BULLETIN WINTER 2009 MEDICAL BULLETIN WINTER 2009 13 T T STREBLE O : SC O T O PH

‘Complementary’ medicine

A yin-yang dynamic makes the Student National Medical Association copresidents more effective as they combat health disparities

One was born in Rochester, Minnesota, the other in Nsukka, Nigeria. One is 39; the other is 24. One is passionate, maybe even a bit of a hothead; the other is analytical and judicious. Both are deeply committed to medicine and to combating health disparities —locally and globally. Together, as copresidents

of the University of Minnesota’s chapter of the Office of Minority Affairs and public, about health-care disparities Complementary strengths Vastly different backgrounds of the Student National Medical Associa- Diversity. The group meets monthly inform medical students Suzanne here and around the world,” she says. There’s a definite yin-yang dynamic in tion (SNMA), Suzanne Garber and and sponsors a wide array of lectures Garber and Ngozika Okoye, their Garber’s and Okoye’s collaboration. “We attitudes toward health care, Ngozika Okoye make a formidable team. and events. Garber’s upbringing informs her commitment to the SNMA, too. “One feed off of each other very well,” Okoye and their coleadership of the The SNMA’s mission is “to achieve University chapter of the Student Choosing to dedicate their scarce free of the important [issues] to me has says. “I’m like the calm for her fire sign. better medical standards for people of National Medical Association. time to the SNMA wasn’t a hard call always been health-care disparities. I’m the water sign — I throw water on color and underserved communities” for Okoye or Garber. Okoye, whose My mom, who is Mexican, worked as a her and cool her down,” she laughs. (see sidebar, page 17). Among its goals family moved from Nigeria to Missis- migrant health nurse for 20 years, and Garber agrees. “I try to be [diplomatic], are increasing the number of culturally sippi when she was 2, knows firsthand it’s just horrendous, the health care but when I get mad about something, competent physicians through volun- of the need the SNMA attempts to fill. these people get. she’s the first one I go to. She makes it teer work in underserved areas and “When I grew up, we were poor immi- so easy for me to ask for help.” helping to educate and encourage grants. We didn’t have health care; “The SNMA became the group that pre-medical and medical students of we used free clinics. My brother had best fit my needs,” Garber continues. Garber’s path to medicine was longer color. About 60 of the 964 medical asthma, and when he had his attacks, “Plus, the people in it are fantastic. I and a bit more circuitous than the students at the University of Minne- where did we go? The ER. That’s where spend 15 hours a day on this campus, average medical student’s. An MIT sota are active SNMA members, says we got most of our care,” she recalls. and it’s nice to know that almost graduate, she began her career as an Mary Tate, SNMA adviser and director “We need to educate people, including everywhere I turn there’s going to be aerospace engineer. After her second providers, would-be providers, and the somebody from the SNMA whom I’ve layoff, Garber was an IT consultant for gotten to know. I have a family here.”

14 M EDICAL BULLETIN WINTER 2009 MEDICAL BULLETIN WINTER 2009 15 The SNMA has really helped put the U of M Medical School on the Okoye says. “We’re hoping that by Another highlight of the year is SNMA’s sending a delegation of people who annual health fair at the Mall of America map. It’s won regional and national awards. The students who join may look like those students, they (MOA). The largest health fair in Min- SNMA, serving is at their core. They just have a heart to serve. may say, ‘Hey, if she was able to do nesota, it served 300 people last year. SNMA at a glance it, there’s no reason I can’t do it.’” Sponsored by the SNMA with support – Mary Tate, SNMA adviser and director of the Office of Minority Affairs and Diversity from the University of Minnesota FOUNDED IN 1964, the Student National Medical To that end, they’ve been working with Medical Center, Fairview, the Medical Association (SNMA) is the nation’s oldest and largest students at Higher Ground Academy, a student organization for students of color and minority School’s Department of Ophthalmology, K–12 St. Paul charter school composed communities. It aims to achieve better medical stan- and the MOA, the all-day event offers mostly of immigrant Somali students. dards for people of color and underserved communities. free screening and information on a The SNMA’s intent is not simply to FF 12 years, working part of that time in wide range of health topics. The University of Minnesota’s SNMA chapter — which HO

L groom future physicians, but to let E England, Germany, and Luxembourg. earned the Region II Chapter of the Year Award in students know about opportunities “It’s direct outreach to the community,” UMM

R She returned to Minnesota, primarily 2007 — is open to all U of M medical students.

IM in health care generally. “Not just Garber says. “We get to talk to people to be with family, and started medical It offers a mentoring program, hosts lectures and O: T T doctors, but also nurses, pharmacists, who have so many different questions. workshops, participates in regional conferences,

PHO school at the University last fall. dentists,” Okoye says. One guy came in with a glucose level and coordinates the largest health fair in Minnesota. Okoye took a more direct route, that was way too high. We have people “Some students have this great apti- The 2009 health fair is slated for March 14 at the completing her undergraduate degree wanting information about pregnancy, tude, but they don’t have support at Mall of America. in biology at the University of Minne- heart attack, substance abuse.” home,” she continues. “Maybe their sota in 2006 and starting medical LEARN MORE AT: parents aren’t educated, or maybe Okoye is buoyed by how the Univer- school in 2007. www.student.med.umn.edu/snma they’re busy with other things. And sity’s health professional students — “Ngozika comes in from the new side, unfortunately, some students, from not just SNMA members — donate The organization works with undergraduates interested and I’m coming from the nontradi- a very young age, are in the company their time and support the cause. in medicine as well. In 2007, the University’s SNMA tional side,” Garber says, so both of people who tell them that this is “The energy is just incredible,” she chapter hosted its first annual Pre-Medical Forum. Interested undergraduates are encouraged to contact younger and older students can relate out of reach. And they start thinking, says. That collaborative spirit shows the SNMA’s affiliated MAPS (Minority Association of to SNMA’s leadership. ‘College is not for me — it’s too hard, in other alliances, too. The SNMA Pre-Health Students) chapter. we can’t afford it,’ not knowing recently cohosted a lecture with the Tate agrees that the pair’s symbiotic that there are all these possibilities Women in Medicine group and is LEARN MORE AT: relationship brings tremendous value out there.” talking with students in the School [email protected] to SNMA. And that, in turn, benefits Mary Tate, director of the Office of Dentistry about collaborating on a www.tc.umn.edu/~maps the Medical School and the University College and medical school are more of Minority Affairs and Diversity, national bone marrow registration drive. advises the University’s award- as a whole. “The SNMA has really accessible than many young people winning chapter of the Student helped put the U of M Medical School realize, Garber adds. “A lot of students Garber and Okoye say their SNMA National Medical Association. on the map,” Tate says. “It’s won aren’t aware of how many [financial experiences will have a lasting impact regional and national awards. People aid] resources are available. That’s part on their lives and will influence their I’ve run into — parents, faculty, people of our mission — explaining to them career choices. Garber is currently outside of the school — know about the how you can do it.” leaning toward surgery and community group’s efforts. The students who join health, while Okoye is intrigued by Outreach with impact SNMA, serving is at their core. They pediatrics and a global focus. Both just have a heart to serve.” Each year, Midwestern members of women are certain that wherever they SNMA and of the Minority Association end up, the service ethic that the SNMA Inspiring future providers of Pre-Health Students (MAPS) gather promotes will remain paramount. The SNMA emphasizes pipeline for a regional conference. The week- programs designed to spark an interest end-long event includes workshops, “I have to give,” Okoye says. “If I don’t M|B in health professions among young lectures, panels, and service and give, I just won’t be happy.”

people of color. “We’re letting the networking opportunities. By SUSAN MAAS, a Minneapolis-based free-lance writer. youth know, ‘There’s a need for you,’”

16 M EDICAL BULLETIN WINTER 2009 MEDICAL BULLETIN WINTER 2009 17 MEDICAL SCHOOL NEW S 18 18 H Bernhard says worries,” and fears stant con and diabetes by constrained longer no life productive and happy a enjoy people help and disease devastating Schulze Schulze from Michigan State State Michigan from Ph. Boivin, Michael expert neuropsychology with worked sota, the at pediatrics of professor associate and investigator pal ( Transplantation and nology the on capitalize will gift The research. diabetes for Minnesota of the to pledge million $40 ate the cognitive function of children children of function cognitive the ate diabetes research in the the in research diabetes to foundation family or individual an by largest second the and history versity diabetes. 1 type with people for cure a into research translating for timeline the shorten to aims and field this in strength children per year. per children 750,000 than more affects disease, the of forms deadly most the of one children. among death A impairment. cognitive long-term shows malaria cerebral of vors survi child four in one that discovered U C its rename the research, diabetes of I in Foundation RICHA THE 1diabetesfor research type U of million Mreceives $40 n recognition of the gift and the future future the and gift the of recognition n frica, malaria is the leading cause of of cause leading the is malaria frica, niversity of Minnesota researchers researchers Minnesota of niversity ering, M. ering, “We have the capacity to cure this this cure to capacity the have “We The gift is the second largest in in largest second the is gift The C erebral malaria may be a majorerebrala malariamaybe cause braininjuryofin handy John, M. John, handy MEDICAL BULLETIN WINTER 2009 D iabetes iabetes D R D ., an internationally recog internationally an ., D M. SCHULZE FA SCHULZE M. D iabetes iabetes D ecember made a made ecember I nstitute. D U ., the study’s princi study’s the ., I U niversity of Minne of niversity nstitute for for nstitute niversity to evalu to niversity I C n Sub-Saharan Sub-Saharan n erebral malaria, malaria, erebral U U U nited States. States. nited D niversity will will niversity niversity niversity ., M.P. ., DII U niversity’s niversity’s M T) the the T) ILY I

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PHOTO: PATRICK O’LEARY inflammation and infection. infection. and inflammation to related exchanges student and opportunities, education graduate posia, sym- joint in resulting Minnesota of University the and institute the between initiated he collaboration the of recognition in Sweden in Institute Karolinska ceremony. award the at remarked M.D., Powell, Deborah Dean School,” Medical the in us of all to mentors and colleagues inspirational are men two these borders, scends programs. international and education global to butions 2008 its Program, Research and Paul Quie, M.D., codirectors of the International Medical Medical International the of codirectors M.D., Quie, Paul and blocked. is the how progress. can cancer treatments for men with advanced prostate cancer. cancer. prostate advanced with men for treatments new of development the to lead potentially and progresses cancer prostate The University of Minnesota in in Minnesota of University The Physiciansforrecognizedglobal engagement growth. cancer ( tor recep- androgen the inhibits therapy This survival. and growth cancer’s the stop to therapy deprivation androgen often is step next the ineffective, are treatments those If cancer. prostate for treatments treatments. conventional to resistant is that cancer prostate recurrent of progression the block to how on H award. this receive to Kingdom United the and Canada, CancerFoundation. Prostate Investigator Young a received has Minnesota, of University Center, Cancer Masonic the at researcher cancer prostate a Ph.D., Dehm, Scott Award YoungInvestigator Prostatecancerresearcher receives e will use his $225,000 award to continue his research research his continue to award $225,000 his use will e Last May, Peterson also received an honorary medical degree from the the from degree medical honorary an received also Peterson May, Last tran that cultural and scientific both knowledge to commitment their “In contri- outstanding for staff and faculty University recognizes award The With his research award, Dehm will create laboratory models that show show that models laboratory create will Dehm award, research his With Surgery and radiation therapy are the most common common most the are therapy radiation and Surgery States, United the in researchers 19 of one is Dehm A R), a type of hormone receptor in the prostate that promotes prostate prostate promotes that prostate the in receptor hormone of type a R), A R continues to cause prostate cancer growth even after after even growth cancer prostate cause to continues R H e hopes these models will provide better understanding of how how of understanding better provide will models these hopes e H owever, this treatment is not curative, and over time the the time over and curative, not is treatment this owever, A M ward for Global Global for ward A | B N ward for 2008 from the the from 2008 for ward

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- M EDICAL S CHOOL N E W S 20 20 when I would do my research for free.” for research my do would I when Center, University of Minnesota, was was Minnesota, of University Center, Cancer Masonic the with researcher to receive this prize money from from money prize this receive to bonus a also is “It says. to,”Gottesman life your dedicated have you research for peers your by recognized being investigators. der, and paranoia and der, disor bipolar schizophrenia, including illnesses mental serious research who individuals exceptional recognizes ( Foundation the from Prize 2008 the received Psychology, of Department the in fellowship senior a and Psychiatry in Professorship Bernstein the efforts. education his for and research illness mental severe to contributions his for honored being is professor A Psychiatryprofessor honoredAPF by non- than higher percent 39 rate cancer colorectal a have Plains surrounding the and sota that found IN of Minnesota, Northern Plains Cancer rates high among American Indians compared with non- with compared cancer gallbladder of rate higher cent per 148 a and cancer, stomach of rate higher percent 135 a cancer, liver of rate higher percent 197 a has also group this that indicate studies Related whites. Indians and and Indians among rates cancer of study University of Minnesota psychiatry psychiatry Minnesota of University David Perdue, M.D., a physician- a M.D., Perdue, David “There is no higher honor than than honor higher no is “There M holds who Ph.D., Gottesman, I. Irving T HE HE EDICAL BULLETIN A lexander Gralnick Investigator Investigator Gralnick lexander FIRST A A merican Indians in Minne in Indians merican A NA laska laska PF) in in PF) A merican Psychological Psychological merican TI

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PHOTO: PATRICK O’LEARY comply with the law, he said he law, the with comply simply than better do to strive should service.” of kind any to indispensible is trust public that learned “I medicine: to applies also it but said, Mondale career, serving. they’re whom those with trust build all above to professionals health-care other and faculty School Medical largely of ence audi his encouraged Mondale Walter President Vice U.S. former fall, last sota Minne of University the at lecture a In foremost,andFirst establish trust Mondalemedicine:on will continue to be challenging,” he said. he challenging,” be to continue will practice your accomplished, is reform if even politics, like is medicine if course, multilayered, complex environment. “ environment. complex multilayered, a in working from stress and challenge constant the with deal to how on crowd the to advice offered Mondale service, roles. leadership future for participants prepare and skills build to designed curriculum three-year a Program, David annual first the of presenter the Mayo Memorial Memorial Mayo the ethical. be to strive should School’s School’s system. health-care evolving today’s regarding large at community the and professionals health-care between dialogue late stimu to meant is and researcher and mentor, surgeon, leader, a as Surgery, of Department the of chair deputy and professor M.D., Rothenberger, David of work the honors series lecture The on Lecture Rothenberger Leaders in both medicine and politics politics and medicine both in Leaders political his in learned he lesson a It’s Drawing from his many years in public public in years many his from Drawing Mondale addressed a full crowd in crowd full a addressed Mondale The lecture also launched the Medical Medical the launched also lecture The E merging Physician Leaders Leaders Physician merging A uditorium as the as uditorium O ctober 2. 2. ctober

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A - - products such as mattresses and com and mattresses as such products to added are PBDEs retardants, flame brominated as known Also (PBDEs). ethers diphenyl polybrominated annually. billion $300 to billion $100 of benefit economic estimated an produced step simple This remained. questions scientific of plenty although gasoline, of out lead phase to moved EPA The potential. earning lifetime to related was turn in which IQ, lower to linked was age young a at lead to Exposure says. Wallinga development, intellectual children’s harming be might gasoline in lead that showed research because example, for smarter, and healthier lot a make.” can we investments public best the of some are these that argue to is work our of “Part says. he disease,” chronic disease, especially those affecting children. David Wallinga, M.D. (Class of 1989), M.P.A., is working to eliminate environmental causes of Topping Wallinga’s hit list today: today: list hit Wallinga’s Topping are today Kids before. done been It’s

production can be a complicated complicated a be can production says. he them,” use environment. larger the and food into seep can and wrapping, food and boxes, lunch toys, bottles, baby as such kids, for products vinyl to added often are phthalates and lead like compounds Toxic groups. environmental some by plastic” poison “the labeled been has which (PVC), chloride vinyl babies. breastfeeding for dangerous be potentially could which humans, in milk breast in prevalent more tially exponen becoming they’re today and studies, animal in development brain disturbed to linked been has that icals chem of class a to belong they But says. Wallinga intent,” good “with puters Eliminating even one chemical from from chemical one even Eliminating let’s so alternatives, safer are “There poly- targets: Wallinga’s of Another

- PHOTO: SCOTT STREBLE BY N BY implications.” big really have they steps, forward those take do we when “And says. he it,” do we but easy, never is jobs our in make we progress the think “I health. community long-term improve icantly - signif can it believes Wallinga but process, Alumni Connections Alumni MEDICAL BULLETIN WINTER 2009 ICOLE E ICOLE recommends these Web resources: Web these recommends Wallinga chemicals, toxic from ronment envi the protecting and foods safer eating about more learn to want who those For RECOMMENDED

noharm.org keepantibioticsworking.org iatp.org healthylegacy.org healthyfoodinhealthcare.org eatwellguide.org NDRES M | B R ESOU

CES - 25 A LUMNI C ONNECTIONS 26 office, 612-625-0336 or 800-922-1663. 800-922-1663. or 612-625-0336 office, alumni the at Roth Katrina call please reunion, your plan help to like would you If classmates. their with reunite will 1999 and 1989, 1984, 1979, 1969, 1959, 1949, 1954, of classes School’s Medical the year This Center. City Marriott Minneapolis the and Minnesota of University the at 12 and 11 September held be will which 2009, Weekend Reunion for calendars your Mark S during classmates N schoolconnections medical Renewing umn.edu/mb/reunion.cfm. www.mmf. visit festivities, the of show slide a Toview activities. weekend’s the attended guests and alumni 258 total, In 26–27,2008. September on Weekend alumni/awards. www.mmf.umn.edu/ visit please winners, past of list a see to and awards these N The Medical Medical The School. Medical Minnesota of University H outstandingalumniachievements forawardCall nominations: celebrating to be presented September 11 during the 2009 2009 the during 11 September presented be to early 150 alumni reconnected with their their with reconnected alumni 150 early ave the date the ave elp us recognize exceptional accomplishments by those affiliated with the the with affiliated those by accomplishments exceptional recognize us elp ominations must be received by March 13, 2009. For more information about about information more For 2009. 13, March by received be must ominations

Invitations will be sent to members of reunion classes as the date approaches. approaches. date the as classes reunion of members to sent be will Invitations plishments within 15 years of medical school graduation. school medical of years 15 within plishments Medical the is This careers. their throughout community and University, School, Medical the to contributions sional The The Distinguished The The through medical practice, teaching, research, or other humanitarian activities. activities. humanitarian other or research, teaching, practice, medical through community national or regional, local, their to contributions outstanding made M EDICAL BULLETIN H E arly Distinguished Career Career Distinguished arly arold S. Diehl Diehl S. arold A lumni Society is now accepting nominations for three alumni awards, awards, alumni three for nominations accepting now is Society lumni A lumni Reunion Reunion lumni A A lumni lumni ward honors individuals who have made outstanding profes outstanding made have who individuals honors ward A WINTER 2009 ward recognizes Medical School alumni who have have who alumni School Medical recognizes ward A

A ward honors physicians for exceptional accom exceptional for physicians honors ward lumni Society’s most prestigious award. prestigious most Society’s lumni

- M | B 10-year reunion. 10-year and Katie Layon, M.D., catch up at their Classmates Christine Sarkinen, M.D. (left), A lumni Reunion Weekend: Reunion lumni

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PHOTO: TIM RUMMELHOFF had even offered cash to students when when students to cash offered even had school. medical of pressures financial the with deal them helping for especially students, to ment commit his for known was Gault 1984, to 1972 from School Medical the of dean life.” of walks all from patients healed and students; medical for tirelessly advocated world; the across schools medical with partnerships established students; and colleagues, classmates, countless inspired he member, faculty “During his time as a student and M.D. Powell, Deborah Dean School Medical says retirement,” his into well and dean as tenure his throughout students its and School Medical our for advocate devoted a was who Gault, home. Paul St. his at cancer pancreatic of 11 December died School, Medical Minnesota of eristy Univ the of alumnus and dean former N Former dean was PHOTO: COURTESY OF CHARLES HORWITZ, M.D. Former dean was . L. (“ L. . member of the Class of 1950 and and 1950 of Class the of member A of loss the at saddened are “We students in need. in students H H A scholarship fund established by by established fund scholarship orwitz, M.D.,orwitz, will support medical Ph.D.,orwitz, and her husband, Charles N EA L ”) GA ”) O n a few occasions, he he occasions, few a n ULT H J e was 88. was e r ., M.D. ., , beloved, H

elene

eal eal - - committed to students, international collaboration committed to students, international collaboration whom she found to be bright, giving, giving, bright, be to found she whom students, medical with working enjoyed at the Minnesota Medical Foundation. Medical Minnesota the at programs related and aid student of tor direcas students shethat,Before served times. emotional and financial, academic, difficult through get students medical Minnesota of University helped she years, 19 last the for School Medical the A students. helping and mentoring career thereafter. years many for research and scholarships for support philanthropic raise to continued he and 1992, 1959to from trustees of board its on serving Foundation, cal Medi Minnesota the to leadership and today. flourish to continues that partnership a collaboration, international first School’s Medical the sparked visit Medical Medical H Rememberingadvisertrusted a Seoul at while system education medical the rebuild to helped he where Seoul, in lived family his and Gault War, Korean the of wake the In collaborations. international ing facilitat about passionate was also Gault education. their finance students medical help to funds several create to 1994, in died who physician and alumna sity Univer a Sarah, wife, his and Gault led commitment This broke. flat were they dents long after his retirement in 1996. in retirement his after long dents stu medical for mentor a as and 1991 to s associate dean for student affairs at at affairs student for dean associate s elene During her career, career, her During service exemplary provided Gault In addition to his devotion to students, students, to devotion his to addition In H A orwitz, Ph.D., spent her entire entire her spent Ph.D., orwitz, lumni Society Board from 1973 1973 from Board Society lumni N ational University. This This University. ational H e also served on the the on served also e H orwitz always always orwitz

- - - financial burdens. financial students’ relieve help to established earlier had they fund scholarship a to requested that memorials be directed directed be memorials that requested pathology and medicine tory M.D., a University professor of labora of professor University a M.D., Charles husband, her with she that surprising wasn’t it a brain tumor. To many who knew her, for treatment following 66 age at died her to be wise and approachable. and wise be to her found students turn, In committed. and the Minnesota Medical Foundation. Foundation. Medical Minnesota the through Fund Study International Student Drs. the to directed be memorials that requested A Mayo Minnesota’s of University the at 16 1994. in Medicine of College Seoul of alumnus ary 1992. in Japan N O standing standing A Medical the by given award highest the Program in in Program the for council advisory leadership the on served and University the at health sexual in chair endowed first world’s the 2008; the the 2008; A Minnesota of University uditorium. In lieu of flowers, Gault Gault flowers, of lieu In uditorium. ward, presented to him in in him to presented ward, lumni Society; the University’s University’s the Society; lumni eck Ribbon, given by the emperor of of emperor the by given Ribbon, eck rder of the Rising Sun, Gold Rays with with Rays Gold Sun, Rising the of rder Sadly, on on Sadly, memorial service was held January January held was service memorial A A A dditionally, Gault helped establish establish helped Gault dditionally, mong his many awards were the the were awards many his mong N A eal and Sarah Gault Medical Medical Gault Sarah and eal H chievement chievement H arold S. Diehl Diehl S. arold O uman Sexuality. uman ctober 24, 2008, 2008, 24, ctober H e was also made honor made also was e N A ational University University ational ward; and the the and ward; A lumni Service Service lumni A H ward, ward, A — orwitz, orwitz, ugust of of ugust —

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- the Medical School. School. Medical the recognizes the the recognizes H Gold the of members to given erence pref with need, financial demonstrated a have who students School Medical to scholarships provide will Students for Fund Scholarship mmf.umn.edu/giveto/horwitz. www. visit Students, Medical Altruistic for Fund Scholarship Horwitz Charles and Helene Drs. the to gift a Tomake www.mmf.umn.edu/giveto/gault. visit Fund, Study International Student Medical Gault Sarah and Neal Drs. the to gift a Tomake visit www.ahc.umn.edu/news/gault. visit Gault and learn more about his life, umanism umanism The Drs. Drs. The A M

To view a brief slideshow on slideshow brief a view To EDICAL BULLETIN lumni Connections lumni H H elene and Charles Charles and elene onor Society. The fund also also fund The Society. onor H orwitzes’ dedication to dedication orwitzes’ A M | ltruistic Medical Medical ltruistic B WINTER 2009 H orwitz orwitz - 27 PHOTO: RICHARD ANDERSON A LUMNI C ONNECTIONS 28 Life Insurance. Insurance. Life sonnel, Control Data, and United Capital per Schools MinneapolisPublic for director 85. Dr. Fox, an internist, served as medical age at 2007, 18, December died Minnesota, JAMES husband, Tom Crook, and 2 children. vived by his wife, Susan; 4 children; 4 grand- 4 children; 4 Susan; wife, his by vived sur is Boman Dr. surgery. replacement hip in pioneer a and Center, Medical Mary’s St. at and gynecology. gynecology. and obstetrics in specialized Cope Dr. 85. age at 2007, 2, December died Minnesota, Virginia, H Giese. Judy wife, former and children; by 1 son and is survived by his wife, Molly; Molly; wife, his by survived is and son 1 by N grandchildren. great- 11 and grandchildren; 19 children; 6 N died Minnesota, Duluth, P great-grandchild. 1 and children; wife, his Medical Group. Dr. Bjornson is survived by School. Medical Minnesota of University the at professor ate Paul-Ramsey St. at radiology of chief as Minnesota, Paul, St. Benedictine Benedictine years. 20 than more for Clinic Duluth the at worked 70. age died Minnesota, Duluth, Memorial Maui dency, and adult protection at the the at protection adult and dency, depen chemical living, transitional health, She also helped programs start in public Center. Medical Mary’s St. at committee tive and as a member of the medical staffexecu Luke’s St. at staff of chief as served Dr. M R In Memoriam chief of radiology at Bethesda Bethesda at radiology of chief as served Bjornson Dr. 87. age at 2008, 31, Maui, Ma’alaea, 1944, ETER ursing ursing O ERSHEL ANCY EDICAL BULLETIN B E nglish practiced in Duluth, where she she where Duluth, in practiced nglish ERT L. L. R. F A H I. E A n orthopaedic surgeon, Dr. Boman Boman Dr. surgeon, orthopaedic n G. G. H ome. Dr. ome. nn-Marie; 6 children; 11 grand- 11 children; 6 nn-Marie;

BOMAN e was president of the board of of board the of president was e B H O . C . B NGLISH ealth Systems, chief of staff staff of chief Systems, ealth X, M.D. X, J H H ORNSON OPE H e founded the the founded e H H ospital and with the Maui Maui the with and ospital e also practiced at the the at practiced also e ospital, and as an associ e was preceded in death E nglish is survived by her her by survived is nglish , M.D. , , M.D. , , M.D. , H , Class of 1945, 1945, of Class , awaii, died January January died awaii, A N , M.D. , ugust 8 at age 57. age at 8 ugust ovember 12 at at 12 ovember , Class of 1965, 1965, of Class , , Class of 1946, 1946, of Class , WINTER 2009 , Class of 1992, 1992, of Class , H A ospital in ospital cademy of of cademy , Class of of Class , E benezer benezer H ospital ospital E dina, dina,

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JAMES 26–27. pages manycontributions onDr. Horwitz’s Jeanette; 3 children; and 4 grandchildren. grandchildren. 4 and children; 3 Jeanette; wife, his by survived is Janecek Dr. years. many for Minneapolis in Center Medical tion H sitional housing to mentally ill individuals. in St. Paul, Minnesota, which provided tran husband, Charles husband, her by 3 children; 4 grandchildren; and former former and grandchildren; 4 children; 3 KENT Cynthia. wife, his by Family Practice. Dr. Gutekunst is survived was a charter member of the the of member charter a was H diseases. pulmonary and surgery thoracic Phoenix, in medicine practiced Gutekunst Dr. 91. age at 6 February died Texas, Plano, 1945, of R 26–27. pages on legacy remarkable Britt-Marie friend, special and great-grandchild, 1 dren, and is survived by his 3 children, 4 grandchil Sarah, wife, his by death in preceded was Gault Dr. 88. age at 11 December died 1950, wife, Shirley Leidl. Leidl. Shirley wife, his by death in preceded was Fox Dr. tion. N. L. (“N L. N. grandchildren. 16 and stepchildren; 2 wife, mer the O In the 1980s, he acquired Familystyle War. Vietnam the in serve to psychiatrists first the of one was Janecek Dr. 75. age at N O H is survived by 3 children and 4 grandchildren. died died establishing a private practice in Phoenix. Phoenix. in practice private a establishing Flagstaff, in practitioner family a as serving years, 52 for medicine ticed e later worked as a general practitioner and e also worked at the Veterans Veterans the at worked also e ew Brighton, Minnesota, died September 14 14 September died Minnesota, Brighton, ew OSCOE ccupational Medicine and was a leader in ctober 24 at age 66. Dr. 66. age at 24 ctober ELENE H A ennepin County Tuberculosis County ennepin ugust 13 at age 80. Dr. 80. age at 13 ugust O. H

JANECE M. H A. G E H EAL lizabeth Webster Curtin; 4 children; children; 4 Curtin; Webster lizabeth N ans Rudnick. Rudnick. ans A ANSON yman. yman. rizona, where he specialized in in specialized he where rizona, ”) G ”) UTE OR K, M.D. K, H W AULT Read about Dr. Gault’s Dr.Gault’s about Read K e is survived by his for , M.D. , IT UNST Z, P Read more about about more Read H

H , Class of 1959, 1959, of Class , J orwitz, M.D.; M.D.; orwitz, orwitz isorwitz survived r ., M.D. ., , Class of 1954, 1954, of Class , h , M.D. , A H .D., cademy of of cademy anson prac anson A A rizona, and rizona, dministra died A , Class Class , , Class of of Class ,

ssocia H omes omes

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- - e - fellow of the the of fellow the of diplomat charter fellow, Bush a was and of University A JAMES great-grandchildren. 5 and grandchildren, 3 children, 3 by survived is and Muriel, wife, his vices. Dr. Kaliher was preceded in death by A Federal and guard coast the to support medical provided initiatives, health public numerous for volunteered School, Tillamook at physician a as served Tillamook, in years 36 for hospital. a owned also he Foley and Pelican Rapids, Minnesota, where in medicine practiced Kaliher Dr. 90. age Portland, 1944, H grandchildren. 6 and children; 3 Jeannine; wife, his by survived is Johnson Dr. Practice. Minnesota. Minnesota. Minneapolis, and Rapids, Pelican Windom, in medicine practiced Johnson Dr. 74. age died Minnesota, Moorhead, A G great-grandchild. 1 and grandchildren; 14 children; 8 June; wife, his by ceded in death by 2 children. children. 2 by death in ceded Laureate Laureate received the the received the of president chapter Minnesota and Center, Community Senior Benedict’s St. of director of the Minnesota Minnesota the of the boards of the St. Cloud Cloud St. the of boards the on served and 1958 in Medicine Internal of Clinic Cloud St. the founded Kelly Dr. 84. age at 18 September died Minnesota, Cloud, St. Duluth, Minnesota, died died Minnesota, Duluth, Minnesota Medical School. School. Medical Minnesota was a clinical professor at the University logic Physicians in in Physicians logic in practice medical a establish helped Koos Dr. dministration, and performed coroner ser llina llina ERALD O LAN H W A A eron Lake, Minnesota, worked for Uro merican Board of Family Practice, and and Practice, Family of Board merican merican College of Physicians. Physicians. of College merican ARD H R. R. H. H. ealth Care System. System. Care ealth A

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H KELLY K A A . N e also taught residents at the the at residents taught also e . merican College of Physician’s Physician’s of College merican merican merican KOOS orth Dakota Medical School School Medical Dakota orth KALIHER O regon, died died regon, H eart eart E , M.D. , dina, Minnesota, and and Minnesota, dina, , M.D. , , M.D. , A A cademy of Family A ssociation, medical medical ssociation, O , M.D. , H , Class of 1947, of Class , ugust 10 at age 78. 78. age at 10 ugust H regon,where he H e later practiced practiced later e H , Class of 1956, 1956, of Class , N e was president president was e ospital and the the and ospital A e also served served also e , Class of 1960, 1960, of Class , H ovember 18 at at 18 ovember ugust 10 at at 10 ugust A e is survived viation viation , Class of of Class , H igh igh H e

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A L O O K B A C K 30

IMAGE COURTESY OF CARL PLATOU, M.H.A. MEDICAL BULLETIN School’s apolis Erling served the mb/MMF70.cfm. milestones, Minnesota

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—

BY KRISTINE MORTENSEN KRISTINE BY beginnings. promising but humble its from reach far a benefactors 66,000 than more from gifts through million $516 raised tion founda the 2003, in concluding nesota, Min Campaign seven-year University’s the During strides. giant making was cancer. and disease heart Stone of St. Paul to support research in Olive and Royal of estate the 1967from in bequest million $4 a and research medical for farmer Dakota North a from 1961 in bequest $200,000 By the turn of the 21st century, MMF MMF century, 21st the of turn the By Medical School and spawns new industry.” new spawns and School Medical the from emanates that research the from about comes it “and says, he have,” we industry strongest the is industry “ state. the and University the both of well-being nomic eco and health the to ever than important more is research and education medical for support cial finan raise to work MMF’s that believes fervently Platou Carl School, Medical the of advocate wall. his on hangs Platou Erling of picture is a key player in the effort to raise the the raise to effort the in player key a is In his advisory roles today, Platou Platou today, roles advisory his In eloquent and tireless A M | B

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T Carl N. Platou, M.H.A. he medical medical he — - -

www.mmf.umn.edu. visit gift, a make to or more learn To Minnesota. atservice the University of research, education, and support for health-related private in annually dollars of Today raises MMF millions MEDICAL BULLETIN WINTER 2009 get this far? It’s thrilling!’” It’s far? this get ever we did world the in ‘How say, would “He declares. nephew his enthralled,” be would “He today? here were he if think staff. support and scientists with ings What might MMF founder Erling Platou Platou Erling founder MMF might What A Look BackLook A ulate the four new build new four the ulate pop and equip to needed funding additional the raise to MMF to up largely be will it but ities, facil the build to bonding in million $292 rized T park. research biomedical new University’s the into life breathe to needed be will that money private he state in 2008 autho 2008 in state he

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A L O O K B A CK MMF board selects new officers, welcomes new members Minnesota Medical Foundation

The Minnesota Medical Foundation NEW OFFICERS The Minnesota Medical Foundation is a 2008 – 2009 BOARD OF TRUSTEES AFFILIATES nonprofit organization that provides support (MMF) elected four new officers, includ- Mary K. Stern, CFA CHAIR Bob Allison Ataxia Research Center for health-related research, education, ing one who is new to the board, and Thomas G. Olson VICE CHAIR International Hearing Foundation and service at the University of Minnesota five other new members to its board of Susan Gunderson SECRETARY University Pediatrics Foundation Medical School and School of Public Health. trustees at the foundation’s annual Eric J. Neetenbeek TREASURER STAFF LEADERSHIP meeting on October 27. For more information or to update your Catherine L. Agee The newly elected officers, who will address, please contact us at: Honorable Clyde E. Allen Jr.* Becky Malkerson Mark R. Allison* PRESIDENT AND CEO serve two-year terms, are: Minnesota Medical Foundation DeWalt H. “Pete” Ankeny Jr. Cindy J. Kaiser Chair: Mary K. Stern, CFA, CEO of MKS McNamara Alumni Center CHIEF FINANCIAL OFFICER AND Associates and the former president of Mary K. Stern Thomas Olson Susan Gunderson Eric Neetenbeek Macaran A. Baird, M.D., M.S.* University of Minnesota VICE PRESIDENT, OPERATIONS CHAIR VICE CHAIR SECRETARY TREASURER Robert H. Bruininks, Ph.D.* Sit Mutual Funds. Stern joined the MMF 200 Oak Street SE, Suite 300 Patricia K. Porter CEO, MKS Associates Executive vice president, CEO, LifeSource President and CEO, David S. Cannom, M.D. board in 2001 and most recently served Minneapolis, MN 55455-2030 VICE PRESIDENT, DEVELOPMENT Business Bank Minnesota Masonic Charities Richard A. Carlson, M.D., F.A.C.R. on the executive committee and chaired 612-625-1440 Frank B. Cerra, M.D.* Sarah E. Youngerman the investment committee. She replaces In addition to Neetenbeek, the follow- establish the N. Bud Grossman Center VICE PRESIDENT, COMMUNICATIONS 800-922-1663 James L. Craig, M.D., M.P.H. John M. Murphy Jr. ing trustees were elected to serve four- for Memory Research and Care at the AND MARKETING [email protected] Gary L. Davis, Ph.D.* Vice chair: Thomas Olson, executive year terms on the MMF board: University in honor of her husband. www.mmf.umn.edu Wendy W. Dayton MEDICAL BULLETIN vice president of the Business Bank and David Cannom, M.D., who previously Selwyn Vickers, M.D., a surgeon and a Timothy J. Ebner, M.D., Ph.D.* Meredith McNab co-managing director of Prime Mort- served on the board from 1999 to 2007. nationally recognized leader in pancre- The University of Minnesota is committed to Mark A. Eustis EDITOR gage, a division of the Business Bank. Cannom founded Los Angeles Cardiology atic cancer research. Vickers joined the the policy that all persons shall have equal John R. Finnegan Jr., Ph.D.* Nicole Endres access to its programs, facilities, and employ- Barbara L. Forster A certified public accountant, Olson Associates and is a clinical professor of University in 2006 as the Jay Phillips ASSOCIATE EDITOR joined the MMF board in 2007. ment without regard to race, color, creed, Stanley M. Goldberg, M.D., F.A.C.S. medicine at the UCLA School of Medicine Professor and Chair of the Department of Jack El-Hai religion, national origin, sex, age, marital sta- Alison B. Good Secretary: Susan Gunderson, CEO and medical director of cardiology at Surgery. Previously, he was chief of the Nicole Endres tus, disability, public assistance status, vet- Peter M. Grant II of LifeSource, a nonprofit organization Good Samaritan Hospital in Los Angeles. gastrointestinal surgery section at the Kate Ledger eran status, or sexual orientation. Beverly N. Grossman that coordinates organ and tissue dona- Mark Eustis, president and CEO of University of Alabama in Birmingham. Susan Maas Sidney Kaplan tion in Minnesota, the Dakotas, and Fairview Health Services, a large non- Winston Wallin, chief executive emeri- Kristine Mortensen Richard E. Kuntz, M.D. portions of western Wisconsin. Gunder- profit health system that includes the tus of Medtronic, Inc. He established the Lesley Schack Richard L. Lindstrom, M.D. son has been an MMF board member Robyn White University of Minnesota Medical Center, Winston R. and Maxine H. Wallin Land- George E. Maas WRITERS since 2006. Fairview. He was formerly president of Grant Chair in Cancer Prevention with his John M. Murphy Jr. Nancy Johnson Treasurer: Eric Neetenbeek, president Regional Ministry Operations at Ascen- wife, Maxine, and played leadership Philip W. Ordway Tim Rummelhoff and CEO of Minnesota Masonic Chari- sion Health in St. Louis, Missouri. roles in establishing the Masonic Cancer Richard T. Ostlund* Scott Streble ties, the philanthropic arm of Minnesota Beverly Grossman, who is a member Center and the John H. Kersey Chair in Treva R. Paparella* Steve Wewerka Masonry. Grand Master of the Masons of Susan B. Plimpton of the University of Minnesota Medical Cancer Research at the University. He cur- FEATURE PHOTOGRAPHERS Minnesota in 1996–97, he is a new rently chairs the Dean’s Board of Visitors. Deborah E. Powell, M.D.* School Dean’s Board of Visitors, a group Woychick Design Robert N. Schulenberg, M.D. trustee as well. of community leaders that advises Medi- For a complete roster, please see the DESIGN AND PRODUCTION James P. Steiner cal School Dean Deborah Powell, M.D. In following page. Sexton Printing James P. Stephenson 2007 she made a significant gift to PRINTING AND DISTRIBUTION Martin J. Stillman, M.D., J.D.* NEW TRUSTEES Selwyn M. Vickers, M.D. Winston R. Wallin Charles F. Wiser Jr.

*Ex officio members

David Cannom, M.D. Mark Eustis Beverly Grossman Selwyn Vickers, M.D. Winston Wallin

Professor of medicine, President and CEO, Member, Medical School Chair, Department of Chief executive emeritus, UCLA School of Medicine Fairview Health Services Dean’s Board of Visitors Surgery Medtronic, Inc.

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Dr. Jakub Tolar is on the front lines—putting everything he knows into making bone marrow transplants safer and better for children battling cancer and other diseases. We’re proud to have Dr. Tolar—one of the premier children’s health researchers in the world—at University of Minnesota Children’s Hospital.

Find out how you can help support children’s health research and care at the University of Minnesota. Go to childrenshealth.umn.edu, or call 612-273-8643.

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