2015-2016 annual report

Howard University College of Pharmacy

2300 Fourth Street, NW Washington, DC 20059 (202) 806-6530 / Fax: (202) 806-4636 http://healthsciences.howard.edu/education/colleges/pharmacy/

Howard University College of Pharmacy 2016 annual report 2015 – 2016 Annual Report | College Leadership Toyin Tofade, MS, PharmD, BCPS, CPCC Dean

Muhammad Habib, Ph.D. Interim Associate Dean for Academic Affairs and Assessment and Chair, Department of Pharmaceutical Sciences

Youness Karodeh, PharmD Assistant Dean for Student Affairs and Director of the Non-Traditional Doctor of Pharmacy Program Howard University College of Pharmacy Olu Olusanya, PharmD 2 Chair, Department of Clinical & Administrative Pharmacy Sciences

Monika N. Daftary, PharmD, BCPS-AQ ID, AAHIVP Vice Chair, Department of Clinical & Administrative Pharmacy Sciences

Oluwaranti Akiyode, PharmD, BCPS, CDE Director of Professionalism and Professional Development

Tamara McCants, PharmD Executive Director, Experiential Program

Centers Center of Excellence Toyin Tofade, MS, PharmD, BCPS, CPCC, Director Soon Park, PharmD, Co-Program Director Celia Williams-Fowlkes, MEd, Program Manager and Director of Admissions and Recruitment

Center for Minority Health Services Research Toyin Tofade, MS, PharmD, BCPS, CPCC, Center Director Mary Maneno, PhD, Co-Program Director

Center for Drug Research and Development Emmanuel Akala, Ph.D., Director

Alumni Association Wallene Bullard, PharmD, President Frederick Munford, MS, DMin, Alumni Liaison

Giving Please continue to support the College of Pharmacy. Our funding priorities for the coming year include; increased scholarship support for students, support of academic programs, and planning for a new building. Please visit our website for additional information. http://healthsciences.howard.edu/education/colleges/pharmacy Thank you! contents

4 Message from the Dean

6 Facts & Statistics

7 Letter from a Student

8 Research Efforts

10 Why I Chose Howard

11 Student Quotes

12 Howard Alumnus Receives 2016 Chauncy I. Cooper Award

13 Faculty Effort

14 Publications

20 Community Service Efforts

22 Funded Grants

24 College of Pharmacy Donors VISION

Howard University College of Pharmacy strives to be a premier College in teaching, learning, research, leadership and service locally and globally.

MISSION

Consistent with the mission of Howard University, the mission of the College of Pharmacy is to provide pharmaceutical education of excellent quality to students with high academic, scholarship and leadership potential, with particular emphasis upon the recruitment, retention and graduation of promising African-American and other ethnically diverse minority students. WE ARE 2015 – 2016 Annual Report

| L.E.A.D.E.R.S. Leadership | Excellence | Accountability | Diversity | Engagement | Relationship | Service

MESSAGE FROM THE DEAN

he College of Pharmacy had another successful year in 2015-2016. This was largely due to the effort made by the faculty, staff students and alumni. After completing a presentation to the Health sciences Howard University College of Pharmacy T board of trustees yesterday. I was told that we are doing a good job. We 4 had 6 patents confirmed, numerous publications and invitations to speak by our faculty. I truly agree with our students who say that HUCOP is one of the best kept secrets. The secret is out and I am very proud to show- case the great work that our faculty and students have accomplished during the past year in this report.

This year I begin my tenure as dean of the college and it is with great joy I join this presti- gious institution. The convocation ceremony on September 23, 2016 brought back memories of commitment and resolve to do what it takes to serve humanity and move the profession forward. Most importantly, I look forward to serving the students, staff, faculty and alumni in any way I can. The work has begun and we are excited for 2016-2017.

In the town hall on September 14, 2016, my vision for the College was clearly stated. We must build upon the successes of our great predecessors, Interim Dean Daphne Bernard and Dean Anthony Wutoh and carry the torch making sure the world knows we are here to serve, we are here to learn, and we are here to lead. Since we are raising leaders to change our world, it is imperative that we model the way as well. We must strive to 1. Improve College pride 2. Increase US presence and reputation 3. Increase funding streams/revenue 4. Increase collaboration

To accomplish this we must: • Have a successful COP accreditation, strong academic program, strong research enterprise, strong and consistent clinical practices • Improve efficiency and effectiveness-implement structures and systems that work and improve the environment of learning and work • Engage faculty and staff and ensure that “The right people are in the right seats on the bus”-Good to great

Students continue to have a variety of opportunities to participate in research, clinical train- ing, and community pharmacy initiatives to enhance the educational opportunities provided through the curriculum. Students are gaining real-world experience in international pharmacy through an international rotations. New partnerships were developed with Lilly and Pfizer. Three of our graduates were selected for the Lilly Fellowship and relocated to Indiana as part Howard University College of Pharmacy

of the first phase. Of special note is that they began with 1 fellow and we were able to con- vert that into 3 fellows because of the quality of the candidates. As a result of the fellowship engagement with Pfizer, an unprecedented number of summer 2016 interns (7) were taken from HU and they all excelled. Quoting from the Provosts newsletter: “Pfizer Pharmaceuticals has committed to providing the initial seed funding of $40,000 per year over two years to de- velop the fellowship in regulatory affairs. The program is designed to help doctoral students | from the Pharmaceutical and Medical Sciences become expert investigators globally.” 2015 – 2016 Annual Report

During the board of trustees meeting on September 22, 2016, I was asked to highlight key points that make HUCOP stand out, our leaders came up with this list:

1. We are situated in the nation’s capital; a. Giving us access to big hospitals, NIH, FDA, USP and pharmaceutical companies where students can have excellent experiential education. 5 b. Student access to government and federal agencies that impact pharmacy law and practice

2. We have a. 150 years of pharmaceutical education experience b. A dynamic Integrated curriculum complete with Inter professional education, cutting edge research opportunities and experiences c. A diverse and multicultural environment that facilitates the delivery of culturally competent care d. Opportunities for students to participate in International Rotations in Ethiopia, Ghana, India, Qatar, South Africa, South Korea, Zambia, and other global sites. e. A competitive tuition among private schools f. Engaged alumni who give back by serving the institution as preceptors, instructors, faculty, mentors, and contributions g. Ambitious students who are intelligent, inquisitive, conscientious, possess leadership qualities, culturally sensitive and compassionate h. Competent and nurturing faculty with national and international reputation(1:10 ratio) i. Caring staff who support the students throughout their tenure (Pharmily) j. Several pharmacists have graduated from our programs, and serve as leaders in academia, industry, community Pharmacy, and entrepreneurial efforts.

3. We are Leaders! You are not JUST another number, we know your name and face. You will experience the personal touch here. Join us!

Please feel free to use this as you talk about HUCOP. There is a lot going on at the College as you will see in the pages below. We look forward to your continued support.

Thank you for all you do to make Howard University College of Pharmacy Proud!

Toyin Tofade, MS, PharmD, BCPS, CPCC. Dean and Professor Facts & Statistics 2015 – 2016 Annual Report |

PharmD Program Scholarships 313...... Total enrollment (Including NTDP) (PharmD) 97...... Graduated (2016, including NTDP) $627,457....Total Dollars Awarded 46...... Entering class (Class of 2020)

Howard University College of Pharmacy Ph.D. Program 9...... Total number of awards 6 (3 foreign government scholarships, 2 Edward Bouchet Scholarships, 1 Graduate School Assistantship and 2 COP Teaching Assistantships) 15...... Total enrollment 1...... Graduates (2016) 0...... Entering class

Academic Training 3...... Postdoctoral fellows 3...... Graduate fellows

Faculty New Faculty 29...... Full Time Clinical & Administrative 2...... Part Time Jacqueise Unonu, PharmD, AAHIVP 300..... Preceptor Faculty New Promotions Oluwaranti Akiyode-Full Professor

Staff. 21 Howard University College of Pharmacy

LETTER FROM A STUDENT Greetings Dean Tofade,

| 2015 – 2016 Annual Report My name is Ginika Ezeude, a P2! I hope this email finds you well. Ms. Trudy

mbarrassingly so, this email is actually long overdo! I meant to email you soon after it happened: what I’m referring to is my encounter with Ms. Trudy later that day of the Town Hall Meeting. What a coincidence. E 7 Her face is flashing through my mind as I type this because I vividly remember your story at the end of your presentation about how Ms. Trudy provided you with a pin on the day of your interview at 7 o’clock in the morning! I remember you saying that her positive energy, willingness to help and her smile made your day that day and that she was and is a Leader in your eyes.

Well, I did what you suggested we students do should we ever bump into her: I thanked her sincerely for her hard work and diligence in all that she does here at HUCOP.

And can you imagine what her reply was to me?

She said, “You know I consider you all to be my children and I just try my best to make this place accommodating for you all so that you all can do well and succeed. Yes, I have children of my own, but when I’m here, you all are my children.”

I was so touched by what she said that I continued to thank her even more profusely because I’d never seen a complete stranger, so-to-speak, express that much genuine concern over my welfare. Though she spoke in plural, it dawned on me that I too was included in her refrain “you all are my children”. I was glad to have gotten the opportunity - as random as it was - to engage with her.

Anyways, I just wanted to share that encounter with you and let you know that I’m very pleased that you highlighted her in your presentation. Honestly, had you not, it is possible that I would have gone through HUCOP not having ever recognized her not to talk of having the chance to interact with her beautiful spirit.

Thank you, Ginika Ezeude :)

Ginikannwa Ezeude B.A. Biochemistry | Barnard College of Columbia University Doctor of Pharmacy Candidate, 2019

Published with permission Thank you Gertrude Batista “Ms. Trudy” for all you do for the college. Research Efforts 2015 – 2016 Annual Report |

The Graduate Program in Pharmaceutical Sciences is offered by the Department of Pharmaceutical Sciences, in conjunction with the Department of Clinical and Administrative Pharmacy Sciences (Pharmacy Administration section), in the College of Pharmacy, Howard University. Due to its location in Washington, DC, the program is able to seek collaborations with governmental agencies as well as other research institutions for training its students. Specifically, the research focus is onPharmaceutics Howard University College of Pharmacy with emphasis on drug delivery (pharmaceutical dosage form design) and nanotechnology 8 (biopharmaceutical applications of nanotechnology), Pharmacokinetics with emphasis in Clinical Pharmacokinetic/pharmacodynamic modeling, preclinical simulation, drug metabolism and disposition studies, modeling methodology for analysis of combined pharmacokinetic/pharmacodynamic data to improve clinical drug development and trial design, Pharmaceutical Chemistry with emphasis on with emphasis on medicinal chemistry, computational modeling and natural products.

Within the Department of Clinical & Administrative Pharmacy Sciences, we have a wealth of research activities and experience. The clinical faculty research activities include the areas of diabetes, HIV/AIDS, infectious diseases, bone health, cardiovascular diseases. Research activities include collaborating with other institutions, teaching grants, and research grants. Pharmacy administration faculty research activities have been in the areas of health services research, patient reported outcomes, pharmacoeconomics, and workforce diversity in STEM/health care professions. Specific research areas in health services research, patient reported outcomes include knowledge and acceptability of new anticoagulation therapies, perceptions and knowledge of HCV testing among older adults, medication adherence among Amharic speaking persons, knowledge and acceptability of generic medications among minority patients, and medication use patterns during pregnancy. Within the area of pharmacogenomics, research has focused on the implementation of pharmacogenomics testing in the area of diabetes and mental health and assessing its impact on improving outcomes patient outcomes. Pharmacoeconomic research areas include cost-effectiveness of nivolumab and ixekizumab, economic evaluation of the herpes zoster vaccine. Workforce diversity related research has revolved around developing educational interventions to promote STEM/healthcare interest, preparation and pursuit. Howard University College of Pharmacy

Grant Productivity COP | 2015 – 2016 Annual Report

9

The College of Pharmacy faculty continue to be very productive with

• 53 publications • 17 posters presentations • 8 abstracts • 15 invited speaking engagements • 5 patents issued for the 2015-2016 acadenic year • 1 clinical invention • Awards Processed $7.4 million WHY I CHOSE HOWARD 2015 – 2016 Annual Report | Johnny Yoko-Uzomah

Awards: Professionalism Recognition Award (2015-2016) GSA Recognized Pharmacy Student of the Year (2015-2016)

Why I chose Howard: chose to come to Howard University College of Pharmacy Howard University College of Pharmacy 10 because of the vast diversity that makes up the college Iand the surrounding community. Being the only pharmacy school in D.C. the opportunities and networking are endless. We are surrounded by the headquarters of many of the organizations that play integral roles in the field of pharmacy such as the FDA and APhA. By having student chapters in almost every pharmacy organization, the College of Pharmacy also gives students the ability to build on their leadership skills. Finally, Howard University College of Pharmacy is a family. By being a smaller school, we have the opportunity to get know each other better, and faculty/staff are always willing to assist students in all their endeavors. I have thoroughly enjoyed my two years thus far in the pharmacy program, and look forward to my remaining time here.

Graduation 2016 Howard University College of Pharmacy Student Quotes

Howard University Howard University Howard College of | College of Pharmacy College of Pharmacy Pharmacy is definitely 2015 – 2016 Annual Report “affords you opportunities“ is probably one of the “one of the best decisions that I can almost DMVs best kept secrets, I have made, they helped guarantee you won’t often times you will find reignite my passion to get anywhere else, the out that we are the first not only want to learn but smaller class size and pharmacy school to do to thrive.” dedicated faculty will or have done a lot.” 11 almost certainly write a hard working student a ticket to success.”

Student Scholarly Efforts

• Christine Tran (Class of 2017) May 2016 Awards - Chapter President of Publications 1) “Overview of Ocular the year nomination (SNPhA national), Anti-VEGF Therapy in the Management Ed and Sandra Ruffin Endowment of Diabetes Complications” scholarship recipient. (Diabetes Spectrum). Co-author with Dr. Akiyode. Pharmacovigilance education module for health professional students in South • Bryanna Gray (Class of 2018) Africa. Patient Information Leaflets for all Publication: “GSA: Stay Connected” HIV treatment regimens in Mozambique (Black Apothecary, Spring 2016) Health system. Award: Graduate Student Assembly Distinguished Chair Award (April 2016) • Annabelle T. Dorion (Class of 2017) Washington Pharmacists Association • Shannon Fitzgerald (Class of 2017) Winner of OTC Competition (Team); Bio metals, poster in med, accepted to International rotation in Livingstone, middle bury Russian school, volunteer for Zambia naloxone trainings regional • Bryandt Douglas (Class of 2017) • Jateh Major (Class of 2017) NCPA Foundation Scholarship, Aflibercept: A Review of Its Use in International rotation in South Africa, the Management of Diabetic Eye Dr. Michael Kim Entrepreneurial Complications. J Pharm Pract., Scholarship recipient, Howard University March 2016 School of pharmacy scholarship recipient. HU Research day-Examining the Role • Alemayehu Akalu (Class of 2017) of Historically Black Colleges and Universities (HBCUs) in Promoting NIH Endowment Scholarship recipient, Diversity in the Pharmacy Workforce Black Lion Tertiary level referral hospital Professional Student Poster Presentation rotation, ADDIS ABABA, Ethiopia (Winning poster) April 2016 A Cost-Effectiveness Evaluation of A Multifaceted Community Pharmacy Intervention to Increase Rates Of Herpes Zoster Vaccination ISPOR Conference (Poster Presentation) Howard Alumnus Receives 2016 CHAUNCEY I. COOPER AWARD 2015 – 2016 Annual Report |

Leonard L. Edloe, B.S.Pharm., M.Div., PharmD, alumnus and vice chairman of the Board of Visitors at Howard University College of Pharmacy, was recently named the 2016 recipient of the Chauncey I. Cooper Award by the National Pharmaceutical Association (NPhA). Howard University College of Pharmacy 12 hauncey I. Copper was the first African American Dean of the College of Pharmacy. Dr. Edloe was Cofficially recognized during the NPhA Annual Meeting and Exposition in Atlanta, held July, 2016.

Dr. Edloe is the retired CEO and former pharmacist at Edloe’s Professional Pharmacies in Richmond, VA, and is the pastor of New Hope Fellowship in Hartfield, VA. He sold his pharmacies a few years ago but stays busy on a lot of boards, as pastor of church, talk show host, a professor of Christian Ethics and doing additional study

Dr. Edloe with Erica Hanesworth in theology and ethics.

While working as a community pharmacist and pharmacy owner for over 40 years, Edloe re- mained committed to the profession and his patients through dedicated service to the APhA Board of Trustees, the APhA Foundation Board of Directors, the mid-Atlantic affiliate of the American Heart Association and the board of the Virginia Commonwealth University Health System Authority. He has received numerous awards, including the Bowl of Hygeia Award, the Terrence Burroughs Leadership Award, the Virginia Retailer of the Year Award and the Pharmacy Excellence Award.

A proud alumnus, Dr. Edloe received his B.S.Pharm. from Howard University, his M.Div. from Virginia Union University, and his PharmD from the University of Florida. Howard University College of Pharmacy Faculty Effort PATENTS AND CLINICAL INVENTION | 2015 – 2016 Annual Report

13 Simeon Adesina Emmanuel Akala Monika Daftary Pradeep Karla

1. Adesina Simeon K. “Composition, Method of 5. Karla Pradeep, European Patent has been Manufacture, and Use of Site-Specific Delivery approved and issued for one of my patent of Bruceolides for Treatment of Cancer and disclosures on May 16, 2016. The full patent Other Diseases”. US Patent Application Number disclosure is now published. The title of 62/257,633. Filing date: 11/19/2015. the patent is “Compositions and method for 2. Akala Emmanuel O. and Adesina Simeon. treatment of ischemic neuronal reperfusion Biodegradable stealth polymeric particles injury” (Patent Number EP20140794763) fabricated using the macromonomer approach (Publication Number EP2994132 A1) by free radical dispersion polymerization: US 6. Karla Pradeep, Patent disclosure published Patent Application No. 12/952843. Granted on December 10, 2015. The title of the patent and Issued by the Patent Office in 2016 US is “Method Of Treating An Ocular Disease 8921429 B2 And Compositions Effective For Treating An 3. Akala Emmanuel O. and Okunola Oluyomi: Ocular Disease” (Patent Publication number: US Patent Application No. 12/952856 “Stealth 20150352177) polymeric nanoparticles for the delivery 7. Karla Pradeep, United States Patent was of bioactive or diagnostic agents”). Patent approved and granted on Feb 2nd, 2016 for published and granted by the patent office the disclosure, “Compositions and method for (United States Patent # 8,772,355 Issued on treatment of ischemic neuronal reperfusion July 8, 2014). injury” (US Patent Number: 9248118). 4. Daftary Monika, A professional practice site with the Infectious Diseases within the Department of Internal Medicine with a primary focus in HIV, HCV, HBV and TB established by Dr. Monika Daftary continues to serve the inner city District of Columbia population with HIV/AIDS. At the site, Dr. Daftary provides the treatment adherence program and other pharmacy related support. Publications 2015 – 2016 Annual Report |

1. Adesina, S. K. and Akala, E. O. 10. Akiyode O. Managing Adverse Effects Related Nanotechnology Approaches for the Delivery to Newer Type 2 Diabetes Medications. of Exogenous siRNA for HIV Therapy. Mol. American Association of Diabetes Educators in Pharmaceutics, (2015),12 (12), 4175–4187,. Practice. 2015;3(6): 38-42 (doi: 0.1021/acs.molpharmaceut.5b00335) 11. Akiyode O. Teaching Professionalism: A 2. Adesina, S. K., Uchechukwu Ezeonyebuchi, Faculty’s Perspective Currents in Pharmacy U., and Akala, E. O. The effect of formulation Teaching and Learning. 2016; DOI:htpp:// variables on drug loading of antitubercular dx.doi.org/10.1016/j.cpt1.2016.03.11

Howard University College of Pharmacy drugs in nanoparticle formulations. 12. Akiyode O, Major J, Ojo A. Aflibercept: Materials Research Express, (2015) 2(9), 14 A Review of its Use in the Management 095403, (http://dx.doi.org/10.1088/2053- of Diabetic Eye Complications. Journal 1591/2/9/095403) of Pharmacy Practice. 2016; DOI: 3. Adesina Simeon K., Ezeonyebuchi 10.1177/0987190016647232 Uchechukwu, Akala Emmanuel O. (2015): 13. Baek JS, Kim BS, Puri A, Kumar K, The Effect of Formulation Variables on Drug Cho CW Stability of paclitaxel-loaded Loding of Antitubercular Drugs in Nanoparticle solid lipid nanoparticles in the presence of Formulations. Materials Research Express 2: 2-hydoxypropyl-β-cyclodextrin. Arch Pharm 095403. Res. 2016; 39(6):785-93. doi: 10.1007/s12272- 4. Adesina S.K., Abadejos B, Ako-Adounvo 016-0753-5. Epub 2016 May 5. AM (2016) Nanoparticle Characteristics 14. Basant N, Lin X, Reid TE, Karla PK, Wang Affecting Efficacy. Journal of Pharmaceutics XS. Discovery of a Novel HDAC2 Inhibitor by and Drug Delivery Research 5:1. a Scaffold-Merging Hybrid Query. Comb Chem doi:10.4172/2325-9604.1000145. High Throughput Screen. 2015;18(7):693-700 5. Adesina, Simeon K. and Akala, Emmanuel 15. Basant, N.; Lin, X-H.; Reid, T-E.; Karla, P. K.; (2015): Nanotechnology Approaches for the Wang, X. S.* Discovery of a novel HDAC2 Delivery of Exogenous siRNA for HIV Therapy. inhibitors by a scaffold-merging hybrid query. Molecular Pharmaceutics 12(12):4175-87. Combinatorial Chemistry and High Throughput 6. Akala Emmanuel O., Adesina Simeon, Screening: Chemoinformatics for Virtual Ogunwuyi Oluwaseun (2016): Computer Screening Special Issue 2015, 18, 693-700 Optimization of Biodegradable Nanoparticles (Invited article) Fabricated by Dispersion Polymerization. 16 Chanie T, Hailemeskel B, ekonnen N., et al. International Journal of Environmental Adverse Drug Events in Hospitalized Children Research and Public Health 13, 0047; doi: at Ethiopian University Hospital: A Prospective 10.3390/ijerph13010047. Observational Study. BMC Pediatrics, 7. Akala, E.O., Adesina S., Ogunwuyi O. (2016). 15;83:2015 Computer Optimization of Biodegradable 1 7. Choi Min, Bisrat Hailemeskel and Panvwa Nanoparticles Fabricated by Dispersion Pansiri. A Survey of Preference and Utilization Polymerization. International Journal of of Drug Information Resources by Senior Environmental Research and Public Health 13, Pharmacy Participants. International Journal of 0047; doi: 10.3390/ijerph13010047 Pharmacy Practice. IJPP-15-0110 8. Akiyode O, Dunkelly-Allen N. 18. Ettienne E, Ofoegbu A, Wingate L, Dunston Ranibizumab: A Review of its Use in G, Augusto J. Pharmaceutical Care Coordination the Treatment of Diabetic Retinopathy in and Genomics in Emerging Markets: A Patients with Diabetic Macular Edema. Business Case for Ghana. International Journal of Pharmacy Technology. 2015. Academy of Business Review 2015;1(1) DOI:10.1177/8755122515599 19. Fortunak, J., “The Business Case for Green 9. Akiyode O, Tran C. Overview of Ocular Anti- Chemistry in Drug Discovery,” in: Green VEGF Therapy in the Management of Diabetic Chemistry Strategies for Drug Discovery. Book Eye Complications. Diabetes Spectrum. 2016; Chapter in the Royal Society of Chemistry 2a(1):44-49. DOI:10.2337/diaspect.29.1.44 Drug Discovery Series, published July, 2015. Howard University College of Pharmacy

20. Fortunak, J., “Raising the Technological Level: 30. Lee S, Teschemaker A, Daniel M, Maneno The Scope for API, Excipient, and Biologicals MK, Johnson AA, Wutoh AK, Lee E. Manufacturing in Africa,” Book Chapter in Calcium, Vitamin D Use among Older Adults Making Medicines in Africa, published by in the U.S.: Results from National Surveys Palgrave Macmillan, September, 2015. 2000 to 2009. Journal of Nutrition and Aging. 2 1. Hailemeskel B and Fullas F. The Use of Urica 2016;20(3): 300-305 Doica (Stinging Needle) as a Blood Sugar 3 1. Lee S, Teschemaker A, Daniel M, Maneno | Lowering Herb: A Case Study and Review of MK, Johnson AA, Wutoh, AK, Lee E. 2015 – 2016 Annual Report the Literature, Diabetes Res. Open J. 2015; Predictive Factors of Vitamin D Inadequacy 1(5): 123-127 Among Older Adults in the U.S. International 22. Hill A, Gotham D, Fortunak J, Meldrum J., Journal for Vitamin and Nutrition Research. Erbacher I, Martin M, Shoman H, Levi, J, 2016 (In Press) Powderly WG, Bowe M “Target prices for 32. Luo, M.; Reid, T-E.; Wang, X. S.* Discovery mass production of tyrosine kinase inhibitors of natural product-derived 5HT-1A receptor for global cancer treatment” Brit. Med. J. binders by cheminfomatics modeling of (Open-Access), 2016(6); e009586, doi:10.1136/ known inhibitors, high throughput screening bmjopen-2015-009586. and experimental validation. Combinatorial 15 23. Hill Andrew, Gotham Dzintars Cooke Chemistry and High Throughput Screening: Graham, Pozniak Anton, Khoo Saye, Chemoinformatics for Virtual Screening Fortunak Joseph., “Target generic prices for Special Issue (2015), 18, 685-692 (Invited novel treatments for drug-resistant tuberculosis,” article) (EACS2015 PS2/4) Conference, Barcelona, 33. Luo, M.; Wang, X. S.; Tropsha, A.* Spain; October 22, 2015 (oral presentation). Comparative analysis of QSAR-based vs. 24. Hill Andrew, Simmons Bryony, Gotham chemical similarity based predictors of GPCRs Dzintars, Fortunak Joseph “Significant binding affinity. Molecular Informatics (2016), reductions in costs of generic production of 35, 36-41. sofosbuvir and daclatasvir for treatment of 34. Mims BC, Curry CE. Constipation, diarrhea, hepatitis C.” (EASL2016 SAT-114). and irritable bowel syndrome. In: Chisolm- 25. Hill Andrew, Simmons Bryony, Gotham Burns, MA, Wells, BG, Schwinghammer, Dzintars, Fortunak Joseph “Significant TL, et.al. eds. Pharmacotherapy principles reductions in generic production costs of and practice. 4th ed. New York: McGraw-Hill; sofosbuvir and daclatasvir for Hepatitis C 2016:333-348. treatment in low- and middle-income countries,” 35. Ogunjirin AE, Fortunak JM, Brown LL, ILC Conference, (ILC2015 RS-1445. ). Xiao Y, Davila-Garcia MI, “Competition, 26. Hill Andrew, Simmons Bryony, Gotham efficacy, and selectivity of analogs of Dzintars, Fortunak Joseph. “Rapid reductions A-84543 for nicotinic acetylcholine receptors in prices for generic sofosbuvir and daclatasvir with repositioning of pyridyl nitrogen” to treat hepatitis C” J. Virus Eradication, 2016; Neurochemical Research, 2015, 40:2131-2141. 2: 28-31. 36. Ogunwuyi Oluwaseun, Adesina Simeon 2 7. Kamal, N., Karla, P., Zidan, A. S. and Habib, and Akala Emmanuel O. D-optimal M.J., “BBB GLUT-Transporter Targeting with mixture experimental design for stealth N-acetyl Glucosamine Coated Pegylated biodegradable crosslinked docetaxel-loaded Multilamellar Liposomes”, Trends in Drug poly-ε-caprolactone nanoparticles fabricated Delivery, submitted, 2016. by dispersion polymerization. Pharmazie (2015)70: 165–176 28. Kamal, Nahid; Cutie, Anthony; Habib, Muhammad J; Zidan, Ahmed S, “QbD 3 7. Ogunwuyi Oluwaseun, Kumari Namita, approach to investigate product and process Smith Kahli A., Bolshakov Oleg, Adesina variabilities for brain targeting liposomes” Journal Simeon, Gugssa Ayele, Anderson Winston of Liposome Research, 25 (3):175-190, 2015. A., Nekhai Sergei and Akala Emmanuel O (2016) “Antiretroviral Drugs-Loaded 29. Kumari Namita, Kulkarni Amol A, Lin Nanoparticles Fabricated by Dispersion Xionghao, McLean Charlee, Ammosova Polymerization with Potential for HIV/AIDS Tatiana, Ivanov Andrey, Hipolito Maria, Treatment” Infectious Diseases: Research and Nekhai Sergei, Nwulia Evaristus, “Inhibition Treatment 2016, 9:21-32 of HIV-1 by Curcumin A, a novel curcumin analog” Drug Design Development and Therapy (2015), 9, 5051-5160. 38. Pansiri P., Hailemeskel B, and Min C. 4 7. Ven N van de, Fortunak J, Simmons B, Preferences and Utilization of Drug Information Ford N, Cooke GS, Khoo S, Hill A. “Analysis Resources by Practicing Pharmacists. of minimum target prices for production of Submitted to International Journal of Pharmacy entecavir to treat hepatitis B in high- and low- 2015 – 2016 Annual Report | Practice. IJPP-(2015)-0109. income countries” J. Virus Eradication, (2015), 39. Rashrash M, Maneno MK, Ettienne E, 1:103-110. Daftary MN. (2016) An Evaluation of Hepatitis 48. Wingate L, Hurst C, Semple M, Coleman C Knowledge and Correlations with Health MS, Navin T, Painter J. Cost-Effectiveness Belief Model Constricts among African Analysis of Screening and Treating U.S. Bound American “Baby Boomers”. Journal of Infection Refugees for Latent Tuberculosis Prior to and Public Health Volume 9, Issue 4, Pages U.S. Arrival. BMC Public Health (2015) Dec 436–442 1;15:1201 40. Rashrash M, Maneno MK, Wutoh AK. The 49. Xia, J.; Tilahun, E. L.; Kebede, E. H.; Reid, Psychometric Testing of a Health Believe T-E.; Zhang, L-R.; Wang, X. S.* Comparative

Howard University College of Pharmacy Model and Theory of Reasoned Action Based modeling and benchmarking data set for Questionnaire on Hepatitis C Perception, human histone deacetylases and sirtuin 16 Testing Among Age Wave Group. Journal of families. J. Chem. Inf. Model. (2015), 55, 374- Epidemiology and Public Health Reviews. 2016 388. (In press) 50. Xia, J.; Tilahun, E. L.; Reid, T-E.; Zhang, L-R.*; 4 1. Reid TE, Fortunak JM, Wutoh A, Wang XS. Wang, X. S.* Benchmarking methods and “Chemo-Informatic Based Drug Discovery of data sets for ligand enrichment assessment in Human Tyrosine Kinase Inhibitors” Curr. Top. virtual screening. Methods (2015), 71, 146–157. Med. Chem., 2016, 16(13): 1452-1462. (Invited article) 42. Reid, T-E.; Fortunak, J.; Wutoh, A.; Wang, X. S.* Cheminfomatic-based drug discovery of human tyrosine kinase inhibitors. Current Topics in Medicinal Chemistry 15 Sep 2015 ABSTRACTS [Epub ahead of print; DOI: 10.2174/156802661 5666150915120814] 1. Aftav, S.; Areda, S.; Atefvahid, S.; Bedada, A.; 43. Sackey B, Akiyode O, Lee E, Frazier R. Chen, F.; Hakeem, S.; Shami, S.; Tanashian, Adverse Effects Associated with Newer Type G.; Teferra, H.; Thompson, A.; Wang, X. S. 2 Diabetes Anti-Hyperglycemic Agents. U.S. A crowdsourced, comprehensive database of Pharmacists. 2015; 40(10): 8-11 rare diseases prevalent predominant in people of African descent: The case study of Lassa 44. Shariat A, Ariyo O, Daftary MN. Therapeutic fever. Howard University Research Week (2016). Management of Autoimmune Hepatitis, U.S. Washington, DC (Apr. 2016) Pharmacists 2016; 41(6) 35-39 2. Bazemore, K.; Bededa, A.; Chen, F.; 45. Smith, K. A., Lin, X., Bolshakov, O., Johnson, A.; McCollum, B.; Quach, P.; Griffin, J., Niu, X., Kovalskyy, D., Ivanov, Shami, S.; Tang, K.; Teferra, H.; Wang, X. S. A., Jerebtsova, M., Taylor, R. E. Akala, A crowdsourced comprehensive database of rare E., Nekhai, S. Activation of HIV-1 with diseases prevalent in African American. Howard Nanoparticle-Packaged Small Molecule Protein University Research Week (2016). Washington, Phosphatase-1-Targeting Compound Scientia DC (Award for Professional Student, Apr. 2016) Pharmaceutica. (2015) 83, 535–548,. (doi: 10.3797/scipharm.1502-01) 3. Hecht Keith A., Healy Regan Fan Jingyang, Kumar, Krishna Development 46. Spinks Crystal B., Zidan Ahmed, Khan and Implementation of a Clinical Oncology Mansoor A., Habib Muhammad, and Pharmacy Learning Module in India, AACP Faustino Patrick J., “Pharmaceutical Annual Meeting, Pharmacy Education (2016), characterization of novel tenofovir liposomal Anaheim, CA. formulations for enhanced oral drug delivery: in vitro pharmaceutics and Caco-2 permeability 4. Martin Michelle, Pharm. D., See Sharon, investigations”, J. of Drug Design, Development Pharm. D., Kumar Krishna, PhD, MPS; and Therapy, submitted, 2016. Advancing pharmacy practice in India through a unique clinical pharmacy learning series; Pharmacotherapy Volume35, Number11, (2015) e217(174) Howard University College of Pharmacy

5. Reid, T-E.; Smith, R.; Zubais, A.; Wang, X. S. Incorporating cheminformatic predictive POSTER tools into structure-based discovery of CCR5 antagonists. Structural Biology Related to HIV/ PRESENTATIONS AIDS (2015). Bethesda, Maryland (Jun. 2015)

6. Reid, T-E.; Xia, J.; Wu, Y-T.; Wang, X. S. 1. - Adouno A. A., Moldthan H., Nagawal R., Cheminfomatic modeling of CXC chemokine |

Marabesi, B. Lemos, R. Karla P. K. (2015) 2015 – 2016 Annual Report receptors. Howard University Research Week Thermo Reversible Buffered Tenofovir Nano (2016). Washington, DC (Award for Post Doc Gel for Vaginal Delivery (AAPS Presentation Fellow, Apr. 2016) Number 3215) 7. Shami, S.; Bazemore, K.; Bededa, A.; Chen, 2. - Adouno A. A., Moldthan H., Nagawal R., F.; Johnson, A.; McCollum, B.; Quach, P.; Marabesi, B. Lemos, R. Karla P. K (2015) Tang, K.; Teferra, H.; Aftab, S.; Areda, S.; (AAPS Presentation Number 3231) Expression Hakeem, S.; Tanashia, G.; Thomas, A.; Atef- of ABC Drug Efflux Transporters in Corneal Vahid, S.; Abadejaos, B.; Addo, E.; Anador, S.; Epithelial Cells Qualitative, Quantitative and Wang, X. S. A crowdsourced, comprehensive Functional Screening database of rare diseases prevalent in people of 17 African descent: The case study of Sarcoidosis. 3. Abbey Yvonne, Puri Reema and Akala Howard University Research Week (2016). Emmanuel O.: “Synthesis and characterization Washington, DC (Apr. 2016) of pH-sensitive crosslinker suitable for fabrication of nanoparticles”. Presented at the 8. Xia, J.; Hsieh, J-H.; Wang, X. S.; Wu, S. 2015 AAPS Annual Meeting & Exposition, Development of knowledge-based pose October 25-29, 2015, Orlando, Florida. (6). filter ensemble to boost ligand enrichment for structure-based virtual screening. The 4. Adesina Simeon, Combination 13th National Symposium of Computer& Nanotherapeutics for Tuberculosis Therapy. Computational Chemistry. (2015) Guangzhou, Invited presentation at the School of Pharmacy China and Health Professions, University of Maryland Eastern Shore on Thursday November 5, 2015. 9. Brown D, Maneno M, Daftary M, Ahmed S, Gajjala J. Risk Factors for 30-day Readmission 5. Akala Emmanuel O Novel Nanotechnology among Patients with Human Immunodeficiency Platforms for Breast Cancer Treatment. (b). Virus Infection in an Urban Teaching Hospital. Novel Nanotechnology Platform for HIV/ APhA 2016 abstract of contributed papers. AIDS Treatment. Presented at the Institute Journal of the American Pharmacists of Pharmaceutics and Biopharmaceutics Association. May 2016, Vol. 56 Heinrich-Heine-University Duesseldorf, 2016 (Host: Prof. Dr. Joerg Breitkreutz ) 10. Dayo Y, Daftary M, Maneno M, Akiyode O, Hailemeskel B, Karodeh Y. Student 6. Akala Emmanuel O. “Evaluating Science Intervention on International Pharmacy Writing Assignments” Presented at 2015- Rotations. APhA 2016 abstract of contributed 2016 Howard University Teaching Assistant/ papers. Journal of the American Pharmacists Associate (TA) Training Institute Organized by Association. May 2016, Vol. 56, issue 3, e42 Howard University Graduate School January 8, (SP-126) 2016 11. Liu L, Daftary M, Maneno M, Gajjala J. 7. Akala Emmanuel O., Nekhai Sergei and Estimation of Fracture Risk in a Human Winston Anderson. Antiretroviral Drugs-Loaded Immunodeficiency Virus positive population Nanoparticles Fabricated by Dispersion in Washington, DC. APhA (2016) abstract of Polymerization for GALT Targetable Drug contributed papers. Journal of the American Delivery System. Oral Presentation by Pharmacists Association. May 2016, Vol. 56 Emmanuel O. Akala at Howard University Research Symposium April 14, 2016. 12. Morrison C, Daftary M, Dayo Y, Maneno M. Comparison of Cardiovascular Risk 8. Akala Emmanuel O.: “Research Grant Assessments from the American Heart Writing and Review” Presented at The Higher Association/American College of Cardiology, Education Technical Assistance Project and the Adult Treatment Panel Human (HE-TAP) Workshop Organized by the U.S. Immodeficiency Virus-infected Population Department of Health and Human Resources- and Appropriateness of Lipid Lowering Office of Minority Health, September 14-16, Treatment. APhA (2016) abstract of contributed 2015 at Howard University Health Sciences papers. Journal of the American Pharmacists Library. Association. May 2016, Vol. 56 9. Akala, Emmanuel O. “Breast Cancer” An 1 7. Kulkarni, A. A., Aguilera, J., Hodges, T., Invited Paper Presented on October 18, 2015 Pietzsch, C. A., Lin, X., Jerebtsova, M., Kont, to Howard University College of Pharmacy, Y. S., Ammosova, T., Ivanov, A., Bukreyev, Kappa Epsilon Kappa Epsilon, Alpha Pi A., Uren, A., and Nekhai, S. “Improving 2015 – 2016 Annual Report | Chapter during breast cancer awareness antiviral activity of 1E7-03, an Ebola virus Brunch. inhibitory small molecule, that targets protein 10. Alem G, Maneno MK, Ettienne E, Wingate phosphatase 1” Howard University Research L. (2016). Serum Vitamin D Deficiency among day, April 2016. The above poster received 1st African American Women in the United States. Prize in “Overall” and “Translational and Clinical International Society for Pharmacoeconomics Sciences” category. (http://researchweek. and Outcomes Research Annual Meeting, howard.edu/public/documents/Research- Washington, DC Symposium-Winners-2016.pdf) 11. Alzahrani MS, Maneno MK, Daftary M, 18. Kulkarni, A. A., Nwulia, E. A., Nekhai, S. Wingate L, Ettienne, E. (2016). Factors N. Pacifichem Conference, December 2015. “Development of curcumin-inspired hybrid Howard University College of Pharmacy Associated with Prescribing Broad-spectrum Antibiotics for Children with Upper Respiratory molecules for the treatment of Alzheimer’s 18 Tract Infections in Ambulatory Care Settings, Disease” 2006-2010. International Society for 19. Derrick Anderson, Samantha Green, Nikkina Pharmacoeconomics and Outcomes Research Hankins and Tamara McCants, PharmD - Annual Meeting, Washington, DC The Student’s Perception on Supplemental 12. Daphne Bernard, PharmD, Tamara McCants, Health Screenings and Outreach Trainings. PharmD, Obi Okafor, PharmD Candidate, American Pharmacist Association, Baltimore, Chijioke Onejeme. PharmD Candidate “Pils”: MD (March 2015) A Peer-To-Peer Mentoring Program To Improve 20. Uzoma Obi, Detron Brown, Onyekachi Academic Progression. American Academy of Nwosu, Ryan Frazier, Ikechukwu Oji, Colleges of Pharmacy, San Diego, CA (July Tamara McCants, PharmD - Effectiveness of 2016) a University-Based Pharmacy Medical Reserve 13. Kumar Krishna, Globalization of Pharmacy Corps in Increasing the Number of Pharmacy Education: Implementation and Delivery of Personnel Trained to Respond During an International Pharmacy Modules. Facilitator Emergency Event. American Pharmacist Round table session, College of Pharmacy, Association, Baltimore, MD (March 2015) Howard university, (presented at AACP 2 1. Chelsie Morrison, PharmD Candidate, meeting 2015 July 15 from 10:00 a.m. to Ahmed Ayodeji, PharmD Candidate, 11:00 a.m. at the Gaylord National Resort and Tamara McCants, PharmD - Innovative Convention Center. pharmacy student-managed care organization 14. Brown Wendy, Mcbane Sarah, Kumar collaborative practice model: impact of Krishna, Cernusca Dan, Decerbo Mark, pharmacy student coordinated asthma Babu Niranjan, Krishnakumar, K. Suresh, education on patient and health system B., Teig Nicole Globalization of Pharmacy outcomes. American Society of Health Education: Everything Starts with Assessing Systems Pharmacists, New Orleans., LA Prior Knowledge; Describe assessment (December 2015) strategies that measure student’s perceptions, 22. Tamara McCants, PharmD, Ashley Crumitie, confidence, and knowledge. Facilitator Round PharmD Candidate, Ryan Frazier, PharmD table session, presented at AACP meeting Candidate, Daphne Bernard, PharmD - Being July (2015), National Harbor, Washington DC, Safe About Male Virility - The “Safeguard 15. Kamal N., Karla P., Zidan A. S. and Habib Your Mojo” Campaign. National Association of M. J. “BBB GLUT-Transporter Targeting with Boards of Pharmacy, San Francisco, CA (May N-acetyl Glucosamine Coated Pegylated 2016) Multilamellar Liposomes” 30th Annual Meeting 23. Detron Brown, MPH PharmD Candidate, of AAPS, Orlando, FL, October 2015. Ryan Frazier PharmD Candidate, Onyekachi 16. Kamal Nahid, Cutie Anthony J, Habib Nwosu PharmD Candidate, Tamara Muhammad and Zidan Ahmed, “ QbD McCants, PharmD Effectiveness of a Approach to Investigate Product and Process University-Based Pharmacy Medical Reserve Variabilities for Brain Targeted Liposomes” 3rd Corps in Increasing the Number of Pharmacy Annual convention of AABPS, August 8, 2015. Personnel Trained to Increase Community Resilience and Respond to an Emergency. National Pharmaceutical Association, Atlanta, GA (July 2016) Howard University College of Pharmacy

24. Major J, Ettienne E, Maneno M, Wingate 7. Fortunak, J, Invited Presentation at UN L (2016). Examining the Role of Historically ANDI (African Initiative for New Drugs and Black Colleges and Universities (HBCUs) Diagnostics); in Promoting Diversity in the Pharmacy 8. Fortunak, J, Keynote presentation at the Workforce. Howard University Research Day, OMICS Green Chemistry International Washington, DC. Awarded outstanding poster Symposium in Orlando, FL, September 14, presentation amongst a professional student in 2015 | biology and biomedical sciences 2015 – 2016 Annual Report 9. Fortunak, J, May 4 and 5, 2016: “WHO/ 25. Major J, Oishi TS, Wingate LT. (2016). UNAIDS technical consultation on alternative Cost Effectiveness of Community drug options for pre-exposure prophylaxis.” Pharmacy Interventions to Promote Herpes This is a two-day training session on treatment Zoster Vaccine. International Society for options, regulatory pathways for approval, Pharmacoeconomics and Outcomes Research intellectual property and licensing selection, Annual Meeting, Washington, DC quality-assurance, procurement, and pricing for 26. Malhani M, Maneno MK, Ettienne E, Wingate initiation of mass treatment programs in Sub- L. (2016). Factors Affecting Adoption of a Saharan Africa for Pre-Exposure Prophylaxis Computerized Physician Order Entry System. for HIV-discordant partners. I will be training 19 International Society for Pharmacoeconomics representatives of country treatment programs and Outcomes Research Annual Meeting, and non-Governmental Organizations along Washington, DC with UNAIDS. 2 7. Oishi T, Major J, Wingate L. (2016). A 10. Fortunak, J, November 25, 2015. Presentation Comparison of the Cost-Effectiveness of to approximately 300 delegates at the UN Community Pharmacy Based Promotion of ANDI meeting in Nairobi, Kenya. Host of ACS Herpes Zoster Vaccine in 60 year olds and 70 Green Chemistry Webinars given 4 times in the year olds. Howard University Research Day, past year to present new innovations in Green Washington, DC Chemistry for sustainability and advances in the global chemistry enterprise. About 1,000 listeners register for each presentation. 11. Fortunak, J, “Green Chemistry and Global INVITED SPEAKER Access to Medicines,” presentation to Chemistry and Biochemistry Department at 1. Fortunak, J, “Antivirals for Treating HIV/AIDS,” Andrews University, MI, February 18, 2016 Presented in a half-day workshop with USAID 12. Habib, M.J., University of Dhaka, Bangladesh. in Arlington, VA, January 18, 2016 Topic: “Discovering More Opportunities than 2. Fortunak, J, “Pharmaceutical Agents for we see for our Pharmacists in Bangladesh”, Hepatitis C,” Presented in a half-day workshop July 23, 2016 with USAID in Arlington, VA, March 24, 2016. 13. Kumar Krishna, Indian Congress of Pharmacy 3. Fortunak, J, “The Role of Chemistry in Global Practice 2016 and 2nd convention of Indian Medicines Access,” presentation to Division of Association of Colleges of Pharmacy, Plenary Natural Sciences, Montgomery College, MD, Speaker Curriculum Mapping and Assessment, November 12, 2015. April 3rd, 2016, Coimbatore, India 4. Fortunak, J, August 16-29, 2015: Two- 14. Kumar Krishna, Indian Pharmaceutical week training course in “Pharmaceutical Congress, December 20, 2015 Minimum Manufacturing,” Course 3 in a Master’s Degree Practice Standards – Global Perspectives, Curriculum at the Kilimanjaro School of Mysuru, India, Pharmacy, Moshi, TZ. 15. McCants, Tamara, Million Hearts Campaigns 5. Fortunak, J, December 2-16, 2015: Two-week Symposium, October 2015 - Community training course in “Current Good Manufacturing Pharmacy Based Enhanced Management of Practice Guidelines for Drug Production,” as Hypertensive Patients, Washington DC Course 2 in a Master’s Degree Curriculum at 16. Wang, X. S., DC CFAR Basic Sciences Core the University of Ibadan, School of Pharmacy. (BSC) Providers’ Day, Washington, DC (May 6. Fortunak, J, December 2-16, 2015: Two-week 2016) “Introduction to Molecular Modeling and training course in “Regulatory Documentation Drug Discovery Core Laboratory” and Marketing Submissions,” as Course 4 in a Master’s Degree Curriculum at the University of Ibadan School of Pharmacy. Community 2015 – 2016 Annual Report | Service Efforts

• Akala, Member of the U.S. Pharmacopeia • Akala, Member USP Dosage Form General Advisory Board for Center for Pharmaceutical Chapter- 788 Particulate Matters in Injection Howard University College of Pharmacy Advancement and Training (20 13-2014-2015- subcommittee 20 2016- to date) • Akala, Grant Review Consultancy • Akala, July 1. 2015 to Date: Appointed (a) NIGMS Review of SCORE Grant a member of a USP (United States Applications ZGM 1 RCB-3 (SC), Pharmacopeia) Expert Committee (the November 2015 General Chapters-Dosage Forms USP’s Expert Committee). USP Expert Committees (b) EXITO Pilot Project Grant Program (follows are responsible for developing and revising format of NIH R03): Oregon Portland State USP standards that comprise its compendia: University 2016 the USP and the NF, USP Compounding (c) National Cancer Institute (NCI) Center Compendium, Herbal Medicines Compendium, to Reduce Cancer Health Disparities Dietary Supplements Compendium, and Food (CRCHD), 2015 Mock Review Session Chemicals Codex (as a. part of 2015 Professional • Akala, Member lJSP Dosage Form Chapter- Development Workshop) at NCI, (Shady 1151 Pharmaceutical Dosage Forms Grove) in Rockville, Maryland Subcommittee 2015-2016 (4). Member USP Joint Subcommittee on nanotechnology 2015- 2016

McKinley High outreach Howard University College of Pharmacy | 2015 – 2016 Annual Report 21 y the Provost and Chief y the Provost Appointed b Appointed Advanced 4 modules of Taught to Served and preceptor as an advisor Academic Officer to serve as Assistant Assistant serve as to Officer Academic International Programs for Director of Pharmacy) (College (each a 4 Pharmacotherapeutics courses as part hour course) credit of the Howard University Ababa – Addis University International Project. at 5 students on international rotations in Ethiopia. sites various

1. 2. 3. of Pharmaceutics the Institute Visit to Akala, and Biopharmaceutics Heinrich-Heine- Dr. Prof. (Host: 2016 Dusseldorf, University Two of the Institute): Director Breitkreutz: Joerg students with Ph.D. interaction presentations, collaborative and discussion on research efforts Dr. Bisrat Hailemeskel Bisrat Dr.

• INTERNATIONAL INTERNATIONAL OUTREACH/EFFORT • Graduation 2016 Graduation Dr. Park with visiting students from Korea with visiting students from Park Dr. le ed with the nal Review Consultancy nal Review pH-sensiti ve biocompatib pH-sensiti ve Pediatric Obesity: Pharmacokinetics Obesity: Pediatric Ex vi vo ski n permeation and Ex vi vo Gulp1 Is Associat Gulp1 Is Real-time monitoring of the monitoring Real-time Hyaluronic Acid-Based Acid-Based Biocompatible Hyaluronic Development of PEGylated cysteine- of PEGylated Development Fabrication of Influencing the Factors Design and optimization of Design and nanoparticles of paclitaxel conjugated conjugated nanoparticles of paclitaxel maleic acid} for poly(styrene-co- Pharmaceutics, Molecular anticancer. 2015 and lmplications for Drug Dosing. Drug Dosing. and lmplications for Clinical Therapeutics 2015 retention studies on chitosan- i studies on chitosan- retention ternary nanogel buprofen-gellan in situ ionic gelation by prepared controlled for a tool technique- transderrnal delivery of ibuprofen International journal of Pharmaceutics 2015 Pharmacokinetics of PEGylated Pharmacokinetics of PEGylated (PLD) in Liposomal Doxorubicin Nanomedicine: Mouse Strains Inbred and Biology, Nanotechnology, Medicine mechanism of ibuprofen-cationic mechanism of ibuprofen-cationic using formation crystanule dextran informatics crystallization process (Cry PRINS) International system journal 2016 of Phanna ceutics, 6 Albumin-Bound Drug NanoparticlesAlbumin-Bound 6 IL Journal Part of (ABDns): 2016 Microencapsulation Assembly Supramolecular for Antiret:roviral of Release Sustained Pharmaceutical Sciences, Drug.]. 2016 modified lysine dendrirners with lysine modified prevention tbiols for reduced multiple injury. freperfusion of hepatic ischemia Molecular Pharmaceutics, 2016 thermosensitive PLGA-PEG-PLGA PLGA-PEG-PLGA thermosensitive bone for BMP-2 containing hyclrogels Journal of applications. regeneration Pharmaceutical 2016 Sciences,

Scientific Jour Scientific ix. viii. vii. vi. v. iv. ii. iii. i.

, Pharmacy Day at the Wilson Wilson at the McCants, Pharmacy Day – Status Provider for Building –Advocacy 2015 DC – October Washington, – 2015 Year McCants, Pharmacist of the Association DC Pharmacy Washington, (d)

• • Funded Grants 2015 – 2016 Annual Report |

• Akala, E.O., Biodegradable Nanoparticles for • Kulkarni, A. “Development of small molecule the Co-delivery of siRNA and Anti-HIV Drugs. HIV Nef inhibitors” District of Columbia Center (E. O. Akala: Mentor; Simeon K. Adesina – PI). for AIDS Research 03.01.2014 – 02.28.2016. DC Developmental (DC D-CFAR) Center for AIDS Research Awards Program. • Kulkarni, A. “Small molecule inhibitors $50,000 of filoviral interferon antagonist assay • Akala, E.O., Howard University Small development” U19 Research Award, National Equipment Grant Award: Institute of Allergy and Infectious Diseases, ®

Howard University College of Pharmacy Role: Akala PI: $39,000 (CLARIOSTAR : High NIH (Co-investigator) Performance Microplate Reader with Advanced 22 • Wang Simon, Alzheimer’s Drug Discovery LVF Monochromators”. Installed in May 2016) Foundation (20130503; Jun. 1, 2013 – May 31, • Akala, E.O., NIH/NCI: 1SC1CA199810-01 2017) Role: Principal Investigator (20% Effort), ($1,132,500:00) Akala (PI) 05/01/15-04/30/18: Total direct costs: $110,000 Title of Project: Novel Nanotechnology Platform Project title: Highly Selective HDAC2 Inhibitors for Breast Cancer Treatment. to Treat Alzheimer’s Disease • Akala, E.O., NIH/NIAID: P30AI087714 (PI) • McCants Tamara, Walgreens Community 09/16/2011 – 05/31/2016: Pharmacy Residency Program ($50,000) Title of Project: The District of Columbia “Establishment of A Community Pharmacy Developmental Center for AIDS Research Residency Program” (DC-CFAR) (Targeting Drug (ARV)-Loaded Submitted July 2015 Multifunctional Nanoparticles to M Cells Funded: November 2015 Overlaying GALT (HIV-1 Reservoir). Project: July 1, 2016 - June 30, 2016 $600,000:00 • McCants Tamara, District of Columbia • Akala, E.O., U.S. - Russian University Department of Health ($50,000) Research Competition (CRDF Global - Peace “MRC Recruitment, Training and Response – and Prosperity Through Science Collaboration) Community Resilience” (Akala PI). Project OISE-15-61155-0 $110,000 Refunded: April 2015 March 2015 – Feb. 2017. Collaborator is my Project: April 1, 2015 – June 30, 2016 former postdoc (Dr. Oleg Bol’shakov now in • McCants Tamara, National Association of South Ural State University in Russia). The County and City Health Officials Agreement money will be shared by the two laboratories NACCHO ($15,000) • Fortunak, Cooperative Development Award; “Prepare DC - Pharmacists Promoting Egyptian Government. Time = 36 months. Total Community Resilience” Award = $9,965,000 of which approximately Submitted February 2016 $2.5 million is allocated as equipment and Funded: April 2016 direct expense for Howard University. Project: April 1, 2016 – July 31, 2016 • Fortunak, Strategic Market Analysis for HIV/ • McCants Tamara, Trusted Health Plan AIDS and Hepatitis C: $56,000 (USAID). ($75,000) • Fortunak, Structured Research Award from “Health Outcomes Research Academic the Clinton Health Access Initiative: $87,200 Fellowship” for personnel and $30,000 for lab supplies Submitted May 2016 ($117,200) Funded: June 2016 HIV/AIDS and Hepatitis C Market Evaluation Project: July 1, 2016 – June 30, 2018 (UNITAID): $803,000 for 3 years. • Wang Simon, Chem Axon Ltd. • Karla, BRIDGE Innovation Funding Grant Educational Grant of Provision of Academic (Karla PK – PI) 08/15-2014 – 06/30/2016 License (Jan. 7, 2011 – present) 20% Effort $50,000 (Award Notification Email Role: Principal Investigator (0% Effort) Received on 06/19/2014. The no cost extension Total annual costs: $44,700 approval till 06/30/2016 was received on Project title: Managing Chemical and Related May 29, 2015) Data via Powerful Cheminformatics Tools Howard University College of Pharmacy

• Wang Simon, China Scholarship Council • Wang Simon, Open Eye Scientific Software, (CSC) of the Ministry of Education Special Inc. Research Grant of Provision of Academic Programs to Training Regional Professional in License (Sep. 5, 2014 – present) West of China (201408615090; Aug. 1, 2016 – Role: Principal Investigator (0% Effort) Jul. 31, 2017) Total annual costs: $10,000 Role: U.S. Mentor (0% Effort) Project title: Structure-based Design of Total direct costs: $21,600, Selective HDAC2 Inhibitors to Treat Alzheimer’s | Project title: Drug Design for HDAC2 Inhibitor Disease 2015 – 2016 Annual Report to Treat Alzheimer’s Disease • National Workforce Diversity • Wang Simon, National Institutes of Health Pipeline Grant HRSA Centers for AIDS Research and Developmental Principal Investigator: Anthony Wutoh Centers for AIDS Research (P30AI087714, Project Co-Director; Co-Investigator: Jun. 1, 2015 – May 31, 2020), Mary Maneno Role: Core Laboratory Director (6.25% Effort) Grant Amount: $500,000 Total direct costs: $3,514,680 • Evaluation of Community-based HIV Project title: The District Of Columbia Center Tests and Treatment Models for Men as a for Aids Research (DC CFAR) Population Difficult to Reach and Retain in 23 • Wang Simon, National Institutes of Health Health Facilities in South Africa. RCMI (G12MD007597; Jul. 1, 2014 – Submitted to CDC Mar. 31, 2019) Grant Amount: $1,028,524.23 Role: Module Coordinator (8.3% Effort) Principal Investigator: Anthony Wutoh Total direct costs: $1,504,213, Co-Principal Investigator: Bisrat Hailemeskel Project title: Biomedical Infrastructure for Health Disparities Research: The Cheminformatics and Drug Discovery Module College of Pharmacy Donors — July 1, 2015 - June 30, 2016

Adams, Roscoe Dinerman Little, Ellen Mapis, Gachomo Joanne Stewart, Chanell

2015 – 2016 Annual Report Adekuoye, Olabampe Dixon Carrington, Karen McCants, Tamara Stewart, Norma | Akala, Emmanuel Douthard, Yolanda McCarthy, Jason Stolpe, Samuel Aladejebi, Rufus Doyle, Wade McDonough, Hasan Taylor, Roberta Allen Meadows, Pamela Drame, Imbi Mims, Beverly Thompson, Faith Blount Anana, Commie Duke, Dolores Mobley, Stacey Toyer McKan, Denise Anderson, Crystal Dutta, Samarendra Monkam, Julius Tucker, Gale Anderson, Janice Edloe, Jr., Leonard Montalvo, Lucy Tyson, Anne Anderson, Kenneth Edwards, Keli Moseley, Kim Tyson, James Anozie, Emmanuel Evbuomwan, Faustian Munford, Fred Utley, Astrid Areh, Samuel Finch, Earl Myles, Cheryl Walker, Jr., Isaac Aryee-Mingle, Agnes Fleming, Gayle Ray Myles, Lewis Warrick, Cynthia Asuncion, Robert Fleming, Stanley Nanton, Robert Watkins, Edwards Asuncion, Zenaida Ford Jefferson, Raneesha Neal, Tricia Watkins, Sr., Richard

Howard University College of Pharmacy Ayuk, Sophie Foster-Dotson, Donna Nguyen, Trinh Watson, Jr., David Barclay, Robin Freeman, Cheryl Norman, Denise Watts, Terry 24 Barkwell III, Sheffield Fulcher, Howard Noumedem, Patricia Weather, Jr. Leonard Barnes, Sharon Gaines, Robert Ohakweh, Bethrand Whetstone Wilson, Kimberly Barnes-Greene, Patty Garland, Douglas Okoro, Chibuzor Whittaker, Alana Beech Siler, Valerie Guess, Jr., Mckinley Olajide, Ifedapo Rosemary Whittico, Mathew Bennett, Allen Guthrie, Pauline Olaleye, Cecilia Williams, Audrey Bernard, Daphne Hale-Holman, Nurlean Olufotobi, Remi Williams, Patricia Betsuamlac, Semereab Hamed, Aundrella Olusanya, Olu Wilson, Jr., Talmage Birch, Postelle Hamilton-Palmer, Debora Opaigbeogu, Chinyere Wineglass, Henry Blount-Thompson, Faith Hardy, Vance Osadolor, Emmanuel Witherspoon, Lauren Boaders-Hemphill, Vicky Harris, James Osun, Babatunde Wright, Marc Bockai, Sahr Harrison, Frances Oyeneyin, Felix Wutoh, Anthony Borders-Hemphill, Brenda Harrison, Thomas Perry, Jr., Sidney Bovell, Howard Henderson, Francis Peters, Terri Corporate and Boyd Whittico, Rebecca Hill, Marcella Phillips, Lenita institutional Donors Bradley, Leroy Hinds-Kinney, Yolanne Phillips, William Albertsons Bradley, Leroy Holder, Hyacinth Pinkett, Martin Astellas Bradley-Baker, Lynette Holland, Anthony Raddick, Hazel Bosons Pharmaceutical CORP. Bradley-Cooper, Pansy Howell, Pamela Raines, Kimberly DBA The Medicine Shoppe Bradshaw, Jr., James Ilora, Ngozi Randall, Jeremy Cardinal Health Brady, Ashanta Jackson, Javier LaShun Ray Fleming, Gayle Clinical Pharmacy Associates Inc. Braynon Brassfield, Eleanor Jackson, Sylvia Reid, Berty CHIMYKE CORPCVS Charitable Trust, Breakenridge, Ann Jacques, Janice Robertson, Joshua Inc. Brice, Lizbeth Jefferson, Raneesha Robinson, Jr., Lester Deloitte Foundation Briscoe, Andria Jenkins Stewart, Norma Rodgers, Nathaniel Dr. C. Uchendu & Associates Inc. Broadnax, Carol Jenkins, Emmanuel Rogers, Tracey East End Community Pharmacy Brown, Frank Johns, Cantorial Roseman, Judith East Pines Pharmacy & Medical Brown, Shantelle Johnson, Chrys Ryan, Alan Equipment Bullard, Wallene Johnson, Hausa Safo, Nana Genentech Burgess, Patricia Johnson-Thompson, Marian Sampson, Robert George Washington University Burwell, Alvin Jones, Elaine Saunders, Frederick Pharmacists Mutual Insurance Buxton, Velmer Jones, Rhonda Scott, David Company Carnegie, Lavern Kapadia, Govind Scott, Elizabeth H & M Specialty RX Inc. Charles May, Caroline Kasimu-Graham, Jawara Sebakijje, Justin DBA Brookville Pharmacy 2 Charles, Duclas Keeys, Christopher Shello, Ruby Rite Aid Chen, Charlene Kelly, Carmen Siler, Valerie Safeway Inc. Clarke, Donna Kim, Michael Sims, Bernard Sanofi Foundation for North America Colquhoune, Tanya King, Rosalyn Sise, Sankung SUPERVALU Pharmacies, Inc. Cooper Williams, Kim Kwende, Jane Skillman, Brenda The Metropolitan Cardiovascular Cooper, Samuel Lawson, Aston Smith Moore, Terri Foundation Crandon-Enyi, Merlyn Leftridge, Zetta Smith, Joan Walgreen Co. Cullors, Jr., Arlen Little, Robert Smith, John G. Wal-Mart Stores Inc. Curry, Jr., Clarence Lomb, Odette Smith, Paul Washington D.C. Pharmaceutical Dallas, Constance Lombardo, Frederic Smith, Tara Associates Davidson, Barbara Lopez, Janice Spencer-Kea, Karen Dieudonne, Jean Lovett, Kenya Azizi Stanley Batipps, Joyce

This list includes donors who provided contributions directly to the College of Pharmacy, as well as donors who contributed to the College through the HU Pharmacy Alumni Association. We apologize for any omissions. Please also contact the College of Pharmacy with any corrections. Thank you.

2015-2016 annual report

Howard University College of Pharmacy

2300 Fourth Street, NW Washington, DC 20059 (202) 806-6530 / Fax: (202) 806-4636 http://www.pharmacy.howard.edu