Product Datasheet

MED26 Antibody

Catalog No: #33633

Package Size: #33633-1 50ul #33633-2 100ul Orders: [email protected] Support: [email protected]

Description

Product Name MED26 Antibody

Host Species Rabbit

Clonality Polyclonal

Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific

immunogen.

Applications WB

Species Reactivity Hu Ms

Specificity The antibody detects endogenous levels of total MED26 .

Immunogen Type Peptide

Immunogen Description Synthesized peptide derived from N-terminal of MED26.

Target Name MED26

Other Names ARC70; CRSP complex 7; CRSP70; MED26; activator-recruited cofactor 70 kDa component

Accession No. Swiss-Prot: O95402NCBI ID: 9441

SDS-PAGE MW 65kd

Concentration 1.0mg/ml

Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide

and 50% glycerol.

Storage Store at -20°C

Application Details

Western blotting: 1:500~1:3000

Images

Western blot analysis of extracts from LOVO cells, using MED26 antibody #33633.

Background

Component of the complex, a coactivator involved in the regulated of nearly all RNA polymerase II-dependent . Mediator

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 functions as a bridge to convey information from gene-specific regulatory to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Ryu S., Nature 397:446-450(1999). Naeaer A.M., Nature 398:828-832(1999). Sato S., Mol. Cell 14:685-691(2004).

Note: This product is for in vitro research use only and is not intended for use in or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2