Electronic Supplementary Material (ESI) for Physical Chemistry Chemical Physics This journal is © The Owner Societies 2013
Supplimentary Information Figure Legends:
S1: Raman spectra of RNA building blocks and related compounds. All spectra are the average of 3 Raman spectra and have been baseline corrected, buffer subtracted and scaled to an effective
5 concentration of 50 mM. (a) Adenine related molecules: adenine (black), adenosine (red) and adenosine monophosphate (blue). The measured concentrations were 47.81 mM, 46.40 mM and 56.75 mM, respectively. (b) Cytosine related molecules: cytosine (black), cytidine (red) and cytidine monophosphate (blue). The measured concentrations were 47.70 mM, 56.74 mM and 55.38 mM, respectively. (c) Guanine related molecules: guanine (black), guanosine (red) and guanosine
10 monophosphate (blue). The measured concentrations were 46.19 mM, 63.90 mM and 46.67 mM, respectively. (d) Uracil related molecules: uracil (black), uridine (red) and uridine monophosphate (blue). The measured concentrations were 48.09 mM, 48.32 mM and 67.64 mM, respectively. (e) Ribose and phosphate molecules: ribose (black), ribose phosphate (red) and sodium phosphate (blue). The measured concentrations were 287.08 mM, 434.58 mM and 47.75 mM, respectively.
15 S2: Second derivative spectra of the measured RNA Raman spectra; SL-HIV1 (black), SL-APTR (red) and SL-SARS (blue). The positions of peaks discussed in the text are noted.
Electronic Supplementary Material (ESI) for Physical Chemistry Chemical Physics This journal is © The Owner Societies 2013
S1:
a
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Electronic Supplementary Material (ESI) for Physical Chemistry Chemical Physics This journal is © The Owner Societies 2013
8000 c GMP Guanosine Guanine 6000
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12000 UMP d Uridine 10000 Uracil
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Electronic Supplementary Material (ESI) for Physical Chemistry Chemical Physics This journal is © The Owner Societies 2013
e Sodium phosphate D-Ribose 5-Phosphate D-Ribose 1800
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Electronic Supplementary Material (ESI) for Physical Chemistry Chemical Physics This journal is © The Owner Societies 2013
Figure S2.
SL-SARS SL-APTR SL-HIV1
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