Autumn 2013 ChemLetter Volume XXXI • No. 4 Dear Friend of , Greetings from UW Chemistry! I hope this edition of the ChemLetter finds you and yours well. It is my pleasure to provide this update on our activities. In this era of rising student demand for science coursework, each successive year brings record-breaking enrollment levels in our courses. To provide a sense of scale, a few more than 6,000 students started as freshmen this year at the UW; our fall quarter enrollment in freshman-level chemistry classes was over 3,000! Nearly 2,000 students are presently enrolled in just one course, CHEM 142, first quarter chemistry for those

Nancy Wade Nancy who enter with a high school-level chemistry background. When I began as department chair, enrollment in this course was just half this number. I am glad no one told me Paul Hopkins, Chair Wade Nancy that on my watch enrollment in this resource-intensive course, which was already our largest, would double. At the other end of this “student pipeline” are the many students who complete bachelor’s degrees in chemistry or biochemistry, or both. The size of this program has now stabilized at about 400 degrees per year, an unusually large number even for a large public university. In this issue I am pleased to report a landmark event. Longtime readers will know that it has been an institutional goal for a great many years to renovate to modern standards the Letter from the Chair 1 rooms in which our freshmen do their laboratory work. We have four large rooms on the second floor of Bagley Hall dedicated to this purpose. About a decade ago, Focus on Research 3 we received funding to renovate the first of these four rooms. This past summer, we Faculty Awards & learned that funding has been approved to renovate the fourth and final lab. Our quest Honors 6 to modernize these spaces, called “something out of Dickens” by a former dean of Undergraduate Education, thus appears to have come to a successful close. This leaves 63rd Lindau Nobel just one final undergraduate laboratory space in Bagley Hall (for students beyond the Laureate Meeting 7 freshman year) in need of renovation. Before leaving this subject, I will note a longer Graduate Fellowships term goal concerning our facilities, the construction of a new building to replace the & Awards 8 now outdated research space in Bagley Hall. Pursuing this goal will no doubt provide a healthy challenge to one or more future chairs. Undergraduate Fellowships & Another new development of the past few months has its origin in the state budget Awards 10 that began on July 1, 2013. At the urging of Governor Inslee, whose interest in and support for affordable clean energy is longstanding, our state legislature allocated funds Doctoral Degrees earmarked for the creation of a Clean Energy Institute at the UW. The center will focus Awarded 12 on advancing the science and engineering of the capture and storage of solar energy. Giving Profile 13 Many of our current chemistry faculty members are expected to contribute to and benefit from the existence of this new institute. I presume that articles on this subject Our Donors 14 will appear in future editions of this publication. New Chemistry Earlier this year, it was our sad duty to report to you the December 2012 passing Endowment 16 of Professor Emeritus Bruce R. Kowalski. Bruce was a luminary, who served for many years on our analytical faculty. He was a pioneer in the field of chemometrics, and a person of great vision, energy, and creativity. We were all saddened to see his life cut autumn 2013 autumn

short. Bruce was to me more than an outstanding analytical chemist and a friend; he was also a valued advisor. Long after his retirement from our faculty, I would call him

—continued on next page ChemLetter 1 Letter from the Chair, continued from page 1

at his new home in Durango to seek his advice on difficult issues. To honor Bruce’s life, and to further his lifelong goal of excellence and innovation, I am pleased to announce that in October the Department established an endow- ment bearing his name, the Bruce R. Kowalski Endowed Fund in Chemistry. Like all other endowed funds, this one will exist in perpetuity. The proceeds of this fund can be spent flexibly by the Department to support students, faculty, or staff. As a founding leader of the Center for Process Analytical Chemistry, Spotlight on Bruce understood the extraordinary value to leaders of funds like this one that Chemical Sciences can be spent flexibly. To encourage you to consider giving to this fund, I am committing the Department to match dollar-for-dollar gifts to this fund during • Professors David Ginger 2013 and 2014, up to a total match of $25,000. Gifts to this fund can be sent to and Alex Jen, along my attention. If you were among the many that knew and admired Bruce, with other researchers, I hope you will consider making a gift. recently reported on the It is my very great pleasure to thank Duane and Barbara LaViolette, who role of electron spin have pledged an extremely generous planned gift to the Department. An article in creating efficient about them and their gift is included in this edition. Duane and Barbara have organic solar cells. been regular attendees of department events, especially our annual awards Their findings were dinner at which we honor student awardees, among others, and at occasional published in the scientific lectures. Their friendship and support have been exemplary; their gift journal Nature. will have great impact. • Professor Sarah Keller As this calendar year draws to a close, I feel that I can in good conscience and Affiliate Professor report to you that the state of the Department of Chemistry at the UW remains of Bioengineering Roy strong. We are fortunate to have an outstanding current group of both faculty Black have helped to and students, and to receive applications every year from those who aspire to unravel some of the be the next generation of faculty and students. We have weathered a stunning mystery surrounding the period in which we witnessed breathtaking declines in the level of state- origin of cells in Earth’s provided financial support that funds the core of our instructional programs, ancient oceans. Their and perhaps turned a corner in the current fiscal year with about 20% of the work describes the lost state funding restored. The latter made possible—for the first time in many unexpected selectivity years—not one, but two years in which we do not need to raise tuition levels of interaction of the for undergraduate students who are state residents. That said, we live in a chemical components competitive world, nationally and even internationally, and the pressure is high of RNA with fatty acids, to be at the top of our game. Your gifts help us to be outstanding in both our which may play a educational and research programs. If you are not already a regular contributor, role in stabilizing the please consider joining the many friends of Chemistry who value what we do, precursors to cellular and help to keep us strong. membranes. As always, I hope you enjoy this edition of the ChemLetter. Please accept my best wishes and please stay in touch. Sincerely, autumn 2013 autumn

Paul B. Hopkins Professor and Chair ChemLetter 2 f o c u s o n r e s e a r c h

New Directions in Energy Research

Earlier this year, Governor Jay Inslee and the State of lyst photoelectrodes for solar water splitting. This pro- Washington announced the creation of the Clean Energy cess bypasses photovoltaic energy conversion by storing

Institute at the . The Clean Energy solar energy directly in the form of hydrogen (H2). Institute “aims to accelerate the creation of a scalable clean • In Professor James Mayer’s lab, researchers explore the energy future by advancing the next generation solar energy fundamental science behind the interconversion of and electrical energy storage materials and devices, and their electrical and chemical energies as well as the integration with systems and the grid. The Institute is an of the production and utilization of chemical fuels. The interdisciplinary initiative focused on developing innovative efficient and inexpensive interconversion of chemical people and programs in the areas of Advanced Materials and electrical energies is one of the great challenges of for Energy and Energy Systems & Integration.” A number our century. This would enable, for instance, much more of Chemistry faculty members at the UW are engaged efficient fuel cell vehicles and the storage of energy from in energy research to further these goals. Here are some intermittent sources such as solar or wind. The materials highlights: for these processes need to be “earth-abundant” (not • Professor Daniel Gamelin’s group is involved in the rare) in order to meet the high demand. They must also development of new inorganic nanocrystal-based be non-toxic, benign materials. Research in the Mayer luminescent solar concentrators (LSCs). LSCs are inex- group is approaching this challenge in a variety of ways. pensive and flexible plastic waveguides that collect solar Simple new catalysts have been discovered for the oxi- ➔ + - energy and concentrate it onto photovoltaics. Made by dation of water to O2, 2 H2O O2 + 4 H + 4 e . These inexpensive solution processing, they can lower the cost are the first examples using copper. This reaction is key of solar energy conversion by reducing the photovoltaic to the formation of chemical fuels, since it provides

cell areas needed and by increasing cell efficiencies. the electrons (reducing equivalents) to make H2 from + Gamelin says, “Luminescent solar concentrators are H or organic fuels from CO2. The Mayer group is also basically just big sheets of plastic that funnel photons developing new electrochemical iron catalysts for the

to solar cells—they are cheap, robust, and work equally reduction of O2 to water, which is the cathode reaction well under diffuse or direct sunlight, qualitatively in a fuel cell. These studies indicate that it will be valu-

expanding the possibilities for solar deployment.” The able to control the proton flow to the O2 as well as the group is also developing composite semiconductor/cata- electron addition. In parallel with these molecular —continued on next page

Wide-band gap (ZnS, ZnSe) Mn2+-doped semiconductor nanocrystals can exhibit sensitized Mn2+ photoluminescence due to rapid energy transfer from excitonic to Mn2+ excited states. When these excited states are closer in energy (ZnCdMnSe, ZnMnTe), thermal repopulation of the excitonic states from the Mn2+ excited state can occur, resulting in luminescence from both states. This phenomenon, first discovered in the Gamelin lab, results in the photo-luminescence spectra pictured here. Complete 2013 population transfer between the excitonic and Mn2+ excited states results in a dramatic change in peak intensities that is highly selective and sensitive to temperature. Below the graph, a photograph of a sample illustrates the transition from excitonic luminescence autumn 2013 autumn 2+ (left) to Mn luminescence (right) as temperature decreases.

Courtesy of Daniel Gamelin ChemLetter 3 e s e a r c h c o n t i n u e d s o n r f o c u

New Directions in Energy Research continued from page 3

studies, students in the Mayer group are also pensive, highly efficient organic solar panels a reality. developing the fundamental proton/electron The polymer, created at the University of Washington transfer chemistry of metal oxide materials such and tested at the University of Cambridge, appears as titanium dioxide, which are used in a variety to improve efficiency by wringing electrical current of energy applications. from pathways that, in other materials, cause a loss of electrical charge. • Professor David Ginger’s group is developing the next generation of solar cells which are inexpensive, • In Assistant Professor Brandi Cossairt’s lab, solar flexible, and efficient. On the materials science and energy research is focused on the development of new engineering side of research, Professor Alex Jen’s light-harvesting materials and on solar energy storage group develops low-cost and efficient polymer solar in the form of energy-dense molecules such as hydro- cells and highly efficient white-light polymer LEDs. gen. The first focus area hopes to maximize the energy These researchers recently reported their collabora- output from cheap materials such as nanocrystalline tive findings in the journal Nature. Organic solar zinc phosphide. The research is challenging, however, cells that convert light to electricity using carbon- because traditional methods for making these based molecules have shown promise as a versatile materials do not work well; new methods will need to energy source but have not been able to match be developed. the efficiency of their silicon-based counterparts. Other members of the Department of Chemistry faculty These researchers have discovered a synthetic, explore areas of catalysis for fuel conversion, hydrogen high-performance polymer that behaves differently storage methods, novel materials for solar cells, and from other tested materials and could make inex- conversion of biomass to chemicals and fuels. n

The images on the left show UV-Vis traces monitoring zinc phosphide formation over time showing growth in absorption across 2013 the visible spectrum along with inset images showing the resulting particles by transmission electron microscopy and their bright luminescence. The images on the right show our general approach to designing hybrid photoelectrochemical systems for the hydrogen evolution reaction that focuses on the construction of inorganic interfaces between the molecular and semiconductor

autumn 2013 autumn components.

Courtesy of Brandi Cossairt ChemLetter 4 Understanding Malaria Mutagenesis

Malaria infects more than 250 million people and kills It is now clear how parasite populations “direct” more than 500,000 per year. Eradication of this disease mutagenesis to the correct locus in their single-copy will be greatly assisted by an understanding of how the genome, how they set the stage for further mutagenesis malaria parasite mutates at extraordinary rates and thus by creating multiple copies of genes at that high value presents a “moving target.” It is of particular interest location, and avoid collateral damage at distant genomic to learn how the parasite mutates rapidly and acquires sites that are not relevant. The findings bring together beneficial traits in a given gene (i) without destroying many scattered known facts about malaria genomics and the function of that gene in parasites that have only one make some strong predictions about how the parasites copy of most genes or (ii) without accidentally damaging may use such mechanisms for evolutionary advantages other parts of their single-copy genome. Professor Pradip beyond drug resistance. In the future, these insights will Rathod and co-workers have shown that malaria parasites lead to identification and blocking of enzymes promoting can acquire localized beneficial traits via a population- malaria mutagenesis and will help prioritize global control based two-step strategy. strategies against malaria. This work was published in Using novel organic molecules with antimalarial PLoS Pathogens and cited as editor’s choice in Science. activity as tools, Rathod’s research group captured The lead author, Dr. Jennifer Güler, began an independent Plasmodium falciparum cells in the act of altering their faculty position at the University of Virginia this fall. DNA at the position in their genome necessary to confer Further Reading drug resistance. Individual parasite cells in a large popula- Guler, J. L.; Freeman, D. L.; Ahyong, V.; Patrapuvich, R.; tion of infected red blood cells, first, randomly duplicated White, J.; Gujjar, R.; Phillips, M. A.; DeRisi, J.; Rathod, 0.1-0.5% of their genome. Most cells amplified irrelevant P. K. Asexual Populations of the Human Malaria Para- parts of the genome and died under drug pressure. One site, Plasmodium falciparum, Use a Two-Step Genomic in a million lucky parasite cells fortuitously duplicated the Strategy to Acquire Accurate, Beneficial DNA Amplifi- gene for the drug target and inherited partial resistance. cations. PLoS Pathog, 2013, 9 (5), e1003375. In a second step, at higher drug pressures, the initial DNA Ash, C. Editor’s Choice: Tuning Haploid Happenstance. duplication at the beneficial locus was further amplified, Science, 2013, 340 (6139), 1377. this time with exquisite precision and favorable kinetics. Since each cell was performing such acts at only one For More Information on the Rathod Laboratory place in the genome of that particular cell, the rest of the Please visit: http://depts.washington.edu/chem/people/ genome in the surviving parasites remained undisturbed. faculty/rathod.html n

Mitochondrion Microneme Golgi cissterna Microtubule Apicoplast

Schematic diagram of the 1 μM long Polar rings deadly merozoite form of the malaria Attachment stalk 2 parasite, Plasmodium falciparum, carrying a mere 5,000 genes in a small 1 25Mb genome. 3 L. H. Bannister et al., Journal of Cell

Science, 2003, 116, 3825–3834. 2013 Micronemes

Rhoptry

Dense granule Nucleus autumn 2013 autumn

Rough endoplasmic Nuclear coated vesicles reticulum ChemLetter 5 6 3 R D L I N D A U N O B E L L A U R E A D S & H O N O R S T E M E E T I N G T Y A W A R F A C U L

Matthew Bush Research Award, American Society for Mass Spectrometry

Charles Campbell B. Seymour Rabinovitch Endowed Chair in Chemistry Elected Member, Washington State Academy of Sciences Gerhard Ertl Lecture Award, Fritz Haber Institute, Max Planck Society Robert Burwell Lectureship in Catalysis, North American Catalysis Society

Michael Gelb Gustavus John Esselen Award for Chemistry in the Public Interest, Northeastern Section of the American Chemical Society

Karen Goldberg Paul B. Hopkins Faculty Award

Presidential Entrepreneurial Faculty Fellow, Chemistry of Department the of Courtesy UW Center for Commercialization top row, l to r: David Masiello, Charles Campbell Samson Jenekhe bottom row, l to r: František Tureček, Sarah Keller Elected Member, Washington State Academy of Sciences

Sarah Keller William Reinhardt Thomas E. Thompson Award, Biophysical Society, Outstanding Referee, American Physical Society Membrane Structure & Assembly Subgroup Bruce Robinson Visiting Scholar, Phi Beta Kappa Society Larry R. Dalton Endowed Professor of Chemistry Mentor Award, UW Postdoctoral Association Jaromir Ruzicka Munira Khalil Miegunyah Distinguished Visiting Fellow, University Camille Dreyfus Teacher-Scholar Award, Camille of Melbourne & Henry Dreyfus Foundation Robert Synovec Gojko Lalic GC×GC Scientific Achievement Award, California CAREER Award, National Science Foundation Separation Science Society

David Masiello František Tureček CAREER Award, National Science Foundation Gustavus John Esselen Award for Chemistry in the OpenEye Outstanding Junior Faculty Award, American Public Interest, Northeastern Section of the American Chemical Society, Computers in Chemistry Division Chemical Society

James Mayer Klaus and Mary Ann Saegebarth Endowed Professor Dow Lecturer in , University of of Chemistry California, Berkeley autumn 2013 autumn Bo Zhang

Distinguished Lecturer in Inorganic Chemistry, Young Investigator Award, Society for Electroanalytical Northwestern University Chemistry ChemLetter 6 6 3 R D L I N D A U N O B E L L A U R E A D S & H O N O R S T E M E E T I N G T Y A W A R F A C U L Chemistry graduate students Alisha Jones and Joan Bleecker were selected to represent the UW last July at the 63rd annual meeting of Nobel Laureates in Lindau, Germany. This year’s meeting featured recipients of the Nobel Prize in Chemistry.

The Lindau Nobel Laureate Meeting is Words of wisdom from Nobel “science Disneyland”; there is always Laureate Edmond Fischer something to do or see and it’s a lot of (Courtesy of Alisha Jones) “ fun. I attended small discussion sections, lunches, dinners, and evening events with I was one of the approximately 625 young Nobel Laureates including Steven Chu, researchers from 78 countries selected to Nobel Prize winning physicist and former attend the 63rd Lindau Nobel Laureate secretary of energy for the Obama adminis- “ Meeting in southwestern Germany. While tration. Chu talked about how difficult it is the application process was a bit onerous for scientists to effect changes in Congress (there were three rounds of the application because “all they wanted was a sound bite process, each one requiring essays, letters and video footage of an angry physicist.” I of intent, etc.), it was most certainly asked him if he ever felt hopeless interacting worth it. with Congress, to which he replied, “No, I’m The week-long meeting consisted of too feisty!” He stressed that more professors formal lectures and informal discussions at the top of their fields need to leave the lab with the Nobel Laureate scientists, as well and serve in the government. There is a real as with fellow students from around the need for scientists who can serve as the “go world. I had the opportunity to get to know between” of research and the public. some of the most important people in our I left the meeting more hopeful and field on both a professional and personal excited than I ever have been about science. level. The Laureates were impressive people Courtesy of Joan Bleecker Joan of Courtesy I would recommend this meeting to any to be around and gave us this advice: If you top to bottom: Joan UW graduate student who wants to meet want a Nobel Prize, don’t seek it. Just do Bleecker with Nobel his/her science heroes and see the impacts what you love, and if what you love turns Laureate Steven Chu of science on the greater community. I am out to be Nobel Prize worthy, you haven’t and Nobel Laureate incredibly grateful to several organizations lost friends or family in the process. I Edmond Fischer at the UW, including the Dean’s Office, recommend that any student who has the the Department of Chemistry, and the opportunity should apply. Meeting young Molecular Biophysics Training Grant for researchers from so many different back- left to right: Alisha funding my travel after the sequester caused grounds definitely enhances one culturally. Jones at the 63rd the NIH to cancel my funding. I made quite a few new friends. Lindau Nobel ­—Joan Bleecker —Alisha “Jonesy” Jones Laureate Meeting: attending a lecture, dancing at Bavarian ” Christian Flemming © Lindau Nobel Laureate Meetings and Courtesy” of Alisha Jones evening, and

“throwing dukes” 2013 autumn with Nobel Laureate Richard Ernst ChemLetter 7 a w a r d s l l o w s h i p s & u a t e f e g r a d

Shoshanna Barnett Yunshan Fan Alisha Jones Martin P. Gouterman Endowed Gary and Sue Christian Graduate Irving and Mildred Shain Endowed Fellowship in Chemistry Fellowship in Chemistry Fellowship in Chemistry

Joan Bleecker Hannah Feldman Troy Kilburn Paul H. and Karen S. Gudiksen Endowed Rowland Endowed Fellowship in Basil G. and Gretchen F. Anex Endowed Fellowship in Chemistry Chemistry Fellowship in Chemistry Early Bird Research Assistantship funded Advanced Materials for Energy Liam Bradshaw by the Mickey and Karen Schurr Distinguished Energy Fellowship Arthur G. Anderson Endowed Fellowship Endowed Graduate Fellowship in in Chemistry Travis Lekich Chemistry Natt-Lingafelter Endowed Fellowship Stephen Carlin Brian Fitz in Chemistry Arthur G. Anderson Endowed Fellowship Amy Scott and Stephen C. Alley in Chemistry Patrick Lestrange Endowed Fellowship in Chemistry Honorable Mention, National Science Andrew Chanez Jonathan Goldberg Foundation Graduate Research Lewis R. and Joan M. Honnen Endowed Honorable Mention, National Science Fellowship Fellowship in Chemistry Foundation Graduate Research Advanced Materials for Energy Jonathan Litz Fellowship Distinguished Energy Fellowship Leon J. Slutsky Endowed Fellowship Joshua Guerrette in Chemistry Tyler Chozinski Basil G. and Gretchen F. Anex Endowed Mary K. Simeon and Goldie Simeon Sophia Masi Fellowship in Chemistry Read Endowed Fellowship in Chemistry Achievement Rewards for College Early Bird Research Assistantship funded Kimberly Hartstein Scientists Seattle Chapter Fellowship by the Gary and Sue Christian Graduate National Science Foundation Graduate Laura Murphy Fellowship in Chemistry Research Fellowship Alvin L. Kwiram/Council for Chemical Samantha Connelly Shushan He Research Endowed Fellowship in 2012-13 Outstanding Teaching Assistant Howard J. Ringold Endowed Fellowship Chemistry in Chemistry Advanced Materials for Energy Jonathan Cox Distinguished Energy Fellowship S. P. Pavlou & D. E. Strayer Endowed Stephanie Hemmingson Fellowship in Chemistry Honorable Mention, National Science Heidi Nelson

2013 Foundation Graduate Research 2012-13 Outstanding Teaching Assistant National Science Foundation Graduate Fellowship Research Fellowship Abhinav Dhall Chelsea Hess Marilyn Werby Rabinovitch Memorial Huong (Ivy) Nguyen Brian R. Reid Endowed Fellowship Eugene S. Mindlin Endowed Fellowship autumn 2013 autumn Fellowship in Chemistry

in Chemistry in Chemistry ChemLetter 8 a w a r d s l l o w s h i p s & u a t e f e g r a d left to right: Andrew Chanez, Abhinav Dhall, Shushan He, Ivy Nguyen, Scott Rayermann, Jennifer Stein, Lauren Wugalter, Yunqi Yan Courtesy of Department of Chemistry of Department of Courtesy

2012–13 Alma Mater Travel Awards Gregory Peterson Sarah Vorpahl Norman and Lillian Gregory Endowed Honorable Mention, National Science Recipients of these travel awards receive Fellowship in Chemistry Foundation Graduate Research funds to present a seminar on their Ph.D. Fellowship research at their undergraduate alma Timothy Pollock mater. David M. Ritter Endowed Fellowship Caroline Weller in Chemistry National Science Foundation Samantha Connelly Graduate Research Fellowship University of Iowa (Iowa City, IA) Scott Rayermann George and Agnes Irene Cady Aaron Whittaker Joshua Guerrette Endowed Fellowship in Chemistry Gary and Sue Christian Graduate University of Hawaii at Manoa (Honolulu, HI) Lloyd E. and Florence M. West Fellowship in Chemistry Sanjay Hari Endowed Fellowship in Chemistry David Williams-Young The (Columbus, OH) Martin Roskoff Benton Seymour Rabinovitch Yue Huang Klaus and Mary Ann Saegebarth Endowed Fellowship in Chemistry Beijing Institute of Technology Endowed Fellowship in Chemistry Early Bird Research Assistantship (Beijing, China) funded by the Basil G. and Gretchen Margaret Scheuermann F. Anex Endowed Fellowship in Erica Ingalls Mickey and Karen Schurr Endowed Chemistry Gordon College (Wenham, MA) Graduate Fellowship in Chemistry Lauren Wugalter Michael Lynch Nicholas Senger Irving and Mildred Shain Endowed University of British Columbia Paul H. and Karen S. Gudiksen Fellowship in Chemistry (Vancouver, Canada) Endowed Fellowship in Chemistry Bernard and Claudine Nist Endowed Erin Riley Jennifer Stein Fellowship in Chemistry University of New Mexico George Hitchings Endowed Early Bird Research Assistantship (Albuquerque, NM) Fellowship in Chemistry funded by the Arthur G. Anderson Advanced Materials for Energy Endowed Fellowship in Chemistry Margaret Scheuermann Distinguished Energy Fellowship Scripps College (Claremont, CA) Yunqi Yan Dana Sulas Reinhardt Family Endowed Guozheng Shao National Science Foundation Fellowship in Chemistry Peking University (Beijing, China) Graduate Research Fellowship Mengxia Zhao Andreas Tillack 2013 Niket Thakkar Larry R. Dalton Fellowship in Humboldt University of Berlin National Science Foundation Chemistry (Berlin, Germany) Graduate Research Fellowship Jessica Wittman

Benjamin Van Kuiken Montana State University 2013 autumn

Klaus and Mary Ann Saegebarth (Bozeman, MT) Endowed Fellowship in Chemistry ChemLetter 9

o w s h i p s & a w a r d s u a t e f e l l r g r a d u n d e

Nicholas H. Aldredge Angela R. Hess Anand Kaul Rex J. and Ruth C. Robinson Endowed Earl W. Davie Endowed Scholarship Mary Gates Research Scholar Scholarship in Chemistry in Chemistry Mitchell Krawczyk Yasaman Azodi Sean Higgins CRC Freshman Achievement Award Zalia Jencks Rowe Scholarship Mary Gates Research Scholar Calvin Le Michael Bocek Benjamin G. Horst Hyp Dauben Award Distinguished Scholarship in Hypercube Scholar Timothy Livingston Large Biochemistry Distinguished Scholarship in Chemistry Distinguished Achievement in Evan A. Boyle Earl W. Davie Endowed Scholarship in Chemistry Research Washington Research Foundation Chemistry Kelly L. MacWhorter Fellowship Levinson Emerging Scholar Donald J. Hanahan Endowed Distinguished Scholarship in Emily Hsieh Scholarship in Biochemistry Biochemistry Levinson Emerging Scholar Mathinia Mohanachandran Margaret E. Bruce Bonderman Travel Fellowship Distinguished Scholarship in Zalia Jencks Rowe Scholarship Wei Huang Biochemistry Jon Chu P. C. Cross Award Alyssa K. Mueller Mary Gates Research Scholar Eric Janke Berkelhammer Book Award Natacha Lou Comandante Distinguished Achievement in Marvin E. Nayan CRC Freshman Achievement Award Chemistry Research H. K. Benson Undergraduate Tuition Michelle Drews Ismail Jatta Scholarship Distinguished Scholarship in Mary Gates Research Scholar Washington Research Foundation Biochemistry Marilyn Werby Rabinovitch Memorial Fellowship President’s Medal Fund in Chemistry Award Derek T. Nhan Marissa Fletcher Washington Research Foundation Mary Gates Research Scholar Fellowship

Kenji Fujitani Marilyn Werby Rabinovitch Memorial Fund in Chemistry Award left: Matthew Sonnett in the Gelb group lab; right: Marvin Nayan Carolyn Gunthardt presents a poster. ACS Outstanding Student in Inorganic Chemistry Distinguished Achievement in Chemistry Research

Caroline Hassan Marilyn Werby Rabinovitch Memorial Fund in Chemistry Award

Vicky Herrera Zalia Jencks Rowe Scholarship autumn 2013 autumn

Courtesy of Matthew Sonnett & Marvin Nayan & Marvin Sonnett Matthew of Courtesy ChemLetter 10 o w s h i p s & a w a r d s u a t e f e l l r g r a d u n d e

Adam D. Officer Sreetha Sidharthan Jeremy Tran H. K. Benson Undergraduate Tuition Mary Gates Research Scholar Hyp Dauben Award Scholarship Denis Smirnov Sally Turner ACS Outstanding Student in Analytical Rex J. and Ruth C. Robinson Endowed P. C. Cross Award Chemistry Scholarship in Chemistry Alex Vaschillo Chinonso C. Opara Matthew M. Sonnett Rex J. and Ruth C. Robinson Endowed Rex J. and Ruth C. Robinson Endowed Washington Research Foundation Scholarship in Chemistry Scholarship in Chemistry Fellowship Mary Gates Research Scholar UNCF-Merck Undergraduate Science Distinguished Achievement in Research Scholarship Award Sean Wu Chemistry Research Mary Gates Research Scholar Michelle N. Parks Carla M. Stapleton Rex J. and Ruth C. Robinson Endowed Anna Zemke Berkelhammer Senior Book Award Scholarship in Chemistry Dean’s Medal in the Arts Mary Gates Research Scholar Jack Phillips Jenny Zhou Alex Su Mary Gates Research Scholar Mary Gates Research Scholar Mary Gates Research Scholar Margaux Pinney Aaron Zomback Alexandra Taipale Amgen Scholar Mary Gates Research Scholar Bonderman Travel Fellowship Guillermo S. Romano Amgen Scholar

top row, l to r: Ally Mueller, Emily Hsieh; bottom row, l to r: Michelle Drews, biology & biochemistry double major George Ueda and chemistry & biochemistry double major Amanda Tanadinata proudly don their graduation regalia, Kelly MacWhorter (B.S. Biochemistry) with UW alumna Amanda Evans. ourtesy of Ally Mueller & Emily Hsieh & Emily Mueller Ally of C ourtesy autumn 2013 autumn

Courtesy of Michelle Drews & Kelly MacWhorter & Kelly Drews Michelle of Courtesy ChemLetter 11 d e d g i v i n g p r o f i l e g r e e s a w a r r a l d e d o c t o

Noel Fitzgerald, Ph.D. Chemistry September 2012– Measurement of Dissolved Oxygen in Courtesy of Maxwell Zeigler Zeigler Maxwell of Courtesy Highly Restricted (Picoliter) Volumes O’Malley Kevin of Courtesy Utilizing Thin Film Luminescent Sensors August 2013 l to r: Maxwell Zeigler, Kevin O’Malley (Research Professor Emeritus Lloyd Burgess)

Kate Allen, Ph.D. Chemistry Jennifer Gadd, Ph.D. Chemistry Kevin O’Malley, Ph.D. Chemistry Exploration of Iridium and Rhodium for Single-Molecule Studies for the Investigating Device Physics in Bulk-Hetero- C-H Functionalization Characterization of Synaptic Vesicles junction Organic Solar Cells through Materi- (Professor Karen Goldberg) (Professor Daniel Chiu) als Engineering of Interfaces (Professor Alex Jen, Materials Science Shoshanna Barnett, Ph.D. Chemistry Morgan Gleaves, Ph.D. Chemistry & Engineering) The Discovery and Mechanistic Study of Thiolate Containing, N-heterocyclic Copper-Based Water Oxidation Catalysts Amine Ligands; Investigation Into Theran Riedel, Ph.D. Chemistry (Professor James Mayer) - Intermediates of O 2 and O2 Reactivity, Constraints on Reactivity and Components Application Toward New Ligands for of Nocturnal Nitrogen Oxides James Bollinger, Ph.D. Chemistry Modeling the Active Site of Superoxide (Associate Professor Joel Thornton, Development and Application of Novel Reductase Atmospheric Sciences) Methodologies for the Characterization of (Professor Julia Kovacs) Phospholipase A2 Activity: Targeted Lipidomic Erin Riley, Ph.D. Chemistry Profiling and Interfacial Binding Analysis Joshua Guerrette, Ph.D. Chemistry Single Molecule Photoluminescence (Professor Michael Gelb) Fluorescence-Enabled Electrochemical Micro- Intermittency: The Role of the Host scopy and Nanoscale Electrochemical Analysis (Professor Philip Reid) Jennifer Brigham, Ph.D. Chemistry (Assistant Professor Bo Zhang) Novel Protein Enrichment Strategies for Margaret Scheuermann, Ph.D. Chemistry Proteomic Studies Sanjay Hari, Ph.D. Chemistry Investigations of the Reactivity of Pd and Pt (Associate Professor Dustin Maly) Investigating Inactive Conformations of Complexes with Molecular Oxygen and Char- acterization of a Gold(III)-Alkene Complex Aimee Byrne, Ph.D. Chemistry Protein Kinases (Professor Karen Goldberg) NMR Studies of Polypeptide Structuring (Associate Professor Dustin Maly) and Aggregation David Lao, Ph.D. Chemistry Thomas Schneider, Ph.D. Chemistry (Professor Niels Andersen) Development of Catalytic Processes for the Studies of Sample Compartmentalization by Microfluidic Methods John Choiniere, Ph.D. Chemistry Transformation of Low Value Chemical (Professor Daniel Chiu) The Clinical Diagnosis of Porphyrias by Feedstocks to Value Added Chemicals Tandem Mass Spectrometry (Professor James Mayer) Aaron Whittaker, Ph.D. Chemistry (Professor František Tureček) New Copper-Catalyzed Reactions of Michael Lynch, Ph.D. Chemistry Organoboron and Organosilicon Compounds Michael Coggins, Ph.D. Chemistry Correlating Electronic and Nuclear Motions (Assistant Professor Gojko Lalic) Small Molecule Activation Studies Involving in Ultrafast Photoinduced Charge Transfer Biomimetic Thiolate-Ligated Manganese(II) Reactions with Femtosecond Multi- Ariel Zane, Ph.D. Chemistry Complexes dimensional Spectroscopies Solid-State NMR Characterization of (Professor Julia Kovacs) (Assistant Professor Munira Khalil) Biosilicification Peptides (Professor Gary Drobny) Jonathan Cox, Ph.D. Chemistry Luke Marney, Ph.D. Chemistry New Electrochemical Methods for Studying Metabolomics and the Development of Maxwell Zeigler, Ph.D. Chemistry Nanoparticle Electrocatalysis and Neuronal Nontarget Discovery Analysis Methods for Highly Sensitive Quantitative Microscopy Exocytosis Two-dimensional Gas Chromatography for Cellular and Subcellular Analysis (Assistant Professor Bo Zhang) Time-of-Flight Mass Spectrometry (Professor Daniel Chiu) (Professor Robert Synovec) Sean Fischer, Ph.D. Chemistry Mengxia Zhao, Ph.D. Chemistry autumn 2013 autumn

Hopping Around: Development of Methods Thomas Oates, Ph.D. Chemistry Sensitive and High-throughput Detection, for the Simulation of Non-Adiabatic A Broadband Optical Ring Resonator for Separation and Analysis of Circulating Dynamics in Large Molecular Systems Absorption and Refractive Index Detection Tumor Cells (Associate Professor Xiaosong Li) (Research Professor Emeritus Lloyd Burgess) (Professor Daniel Chiu) ChemLetter 12 d e d g i v i n g p r o f i l e g r e e s a w a r r a l d e d o c t o Leaving a Legacy through UW Chemistry: Duane & Barbara LaViolette Endowed Fund in Chemistry

We are pleased to announce that Duane and Barbara LaViolette have committed a major estate gift to the Department of Chemistry, to establish the Duane & Barbara LaViolette Endowed Fund in Chemistry. This fund will be used to provide student scholarships, as well as to support excellence throughout our department. Duane LaViolette was an undergraduate student in chemistry at the UW, earning his bachelor’s degree in 1947. Duane recounts that though his passion was the LaViolette Barbara and Duane of Courtesy Barbara and Duane LaViolette study of chemistry, he was urged by a family member to attend medical school, which he did for a brief period in the Midwest. But in the end, he was drawn back to chemistry, returning to Seattle, where he took a research LaViolettes have been among our department’s most position in the UW School of Medicine. devoted friends. When asked why they have chosen to In his younger years, Duane was a man of considerable make such a generous planned gift to the Department, athletic ability, avidly pursuing the opportunities afforded composed of almost all of their estate including their by the Northwest for mountain climbing, bicycling, and home, Duane says, “The Department of Chemistry was boating. He met his future spouse Barbara while docking very good to me after I returned from the war, so now I his boat in Portage Bay when she was working in the UW just want to help the Department.” oceanography laboratories through a U.S. naval program. We thank the LaViolettes for their gift and for making The LaViolettes have been regular participants in the choice to give back to the UW to help others. We hope Department of Chemistry activities for many years, their gift highlights the huge impact higher education can attending colloquia and the annual awards dinner. have on an individual, and in turn on how an individual Department Chair Paul Hopkins believes that the can have huge impact on higher education. n

g h t s F R O M O U R p u b l i s h e d r e s e a r c h h i g h l i Surface Structure of a Biomineralization Protein The extracellular matrix proteins found in mineralized tissues are Nature’s crystal engineers, controlling the growth of inorganic composites such as hydroxyapatite (Hap), the mineral component of bones and tissues. Statherin, the 43 amino acid phosphoprotein that regulates both the primary and secondary nucleation of Hap, is disordered in solution but folds into a well-defined structure on mineral surfaces. This figure shows the structure of statherin adsorbed onto the 001 facet of Hap, obtained using distances and torsion angles (from Professor Gary Drobny’s group), to constrain a molecular modeling algorithm. Structures of proteins adsorbed onto biomaterial surfaces will be useful in the development

of calcification inhibitors and promoters of potential use in human medicine. A better 2013 autumn

understanding of how these proteins recognize and assemble in bioactive fashion on inor- ganic mineral phases could also aid in the development of surface coatings to improve the Courtesy of Gary Drobny biocompatibility of implantable biomaterials and tissue engineering scaffolds. ChemLetter 13 g u s t 2 0 1 3 J u l y 2 0 1 2 – a u O N O R S , o u r D

During the past decade, we have seen a remarkable transition in publicly funded higher education. A decade ago, gift-derived funds played a small role in our programs, funding the occasional student fellowship or lecture. A decade later, we and other public institutions of higher education are heavily reliant upon gift funds for support of our baseline program. Today, annual gifts and endowment-derived funds are critical to every aspect of our teaching and research. Students, faculty, and staff are the beneficiaries of your gifts. The UW Department of Chemistry is extraordinarily fortunate to have literally thousands of friends and alumni, a large fraction of whom contribute generously to our programs. We are deeply indebted to the donors named below. With your help, we are providing state of the art education to the current generation of students. Thank you! If you are among our chemistry or biochemistry alumni who have not given back to the Department of Chemistry, we hope you will reconsider that choice. Our ability to help the current generation of students to achieve their dreams depends upon your gift. Thank you in advance for thinking of our students. If your name is missing or misspelled, we apologize and hope you will let us know.

$10,000 and above $1,000–$4,999 Mr. Gary Schwartz American Cancer Society Dr. Stephen Alley & Ms. Amy Scott Dr. Irving & Mrs. Mildred Shain American Chemical Society Dr. Yola Antipas Dr. Regan & Mrs. Kathy Shea American Society for Mass Spectrometry Mr. Arvid Berg & Ms. Sophia Zervas-Berg Dr. Jean’ne Shreeve ARCS Foundation Mrs. Sheila & Dr. Gerald Berkelhammer Strem Chemicals, Inc. Bill & Melinda Gates Foundation Mr. Paul & Mrs. Susan Bombardt Dr. Daniel Syrdal Burroughs Wellcome Fund BP P.L.C. Mr. Homer Twedt Camille and Henry Dreyfus Foundation Dr. John Brottem Jr. & Ms. Chia Wu Professor Larry Dalton & Dr. Nicole Boand Ms. Susan Hettinger Mr. Lyman Young & Ms. Marion So ExxonMobil Corporation Mr. Donald & Mrs. Patricia Carlberg Gary & Irene Masada Foundation Colonial Metals, Inc. $500 to $999 Gaussian, Inc. Dr. Fred & Ms. Marilyn Dorer Dr. George & Mrs. Gerry Blomgren Drs. Karen & Paul Gudiksen Mrs. Vera Eggers Cascade Internal Medicine, P.S. JNC Corporation Professor Bruce Eichinger & Chevron Corporation Mr. Mark Jones Mrs. Sandra Jackson-Eichinger Dr. Ronald Diesen Drs. R. Irene & Gary Masada ExxonMobil Corporation Mr. James & Ms. Christine Eldridge Ms. Kay Montana RDML Linda & Mr. John Fagan Mr. Robert Frey Jr. M. J. Murdock Charitable Trust Mr. Norm Gregory Dr. Filon & Mrs. Concetta Gadecki Mr. Herbert Smith (D) Mr. Howard & Mrs. Connie Harris Jr. Professor David & Dr. Van Ginger Jr. Drs. Usha & S. Rao Varanasi Ms. Jeanne Hsu Dr. Jackson & Mrs. Rosemary Harrar Washington Research Foundation KinDex Therapeutics, LLC Mr. Larry & Ms. Lani Johnson Professor Alvin & Mrs. Verla Kwiram Mr. Jonathan & Mrs. Allison Joss $5,000–$9,999 Matheson Tri-Gas Dr. James Kirchner & Ms. Jan Kang Dr. Basil & Mrs. Gretchen Anex Mr. Richard Mathies Dr. David & Mrs. Franki Kohler Susan Blake Mrs. Sandra & Mr. John Matsen Mr. Duane & Mrs. Barbara LaViolette The Boeing Company Mrs. Karen & Dr. James Mhyre Dr. Helen & Mr. Gerald Morrow Bridgestone Firestone North American Dr. A. Bruce & Mrs. Joanne Montgomery Dr. Bruce & Mrs. Alice Ronald Tire, LLC Novartis International AG Royal Society of Chemistry Dow Chemical Company Mrs. Marne & Dr. Joseph Osborne Professor Carol Stoel-Gammon & Dr. David & Mrs. Suzanne Dreyer Dr. Raymond & Mrs. Sally Paxton Dr. Richard Gammon DuPont Pfizer, Inc. Mr. David Sunderland Eastman Chemical Company Professor William & Drs. Susanne & Robert Vandenbosch autumn 2013 autumn

Emerald Sky Foundation Mrs. Katrina Reinhardt Dr. J. Daniel Wanwig Ms. Martha Ipsen Dr. Klaus & Mrs. Mary Ann Saegebarth Dr. Edward & Mrs. Judy Zahnow Mr. John & Mrs. Cathy Natt Professor J. Michael & Mrs. Karen Schurr Procter & Gamble ChemLetter 14 g u s t 2 0 1 3 J u l y 2 0 1 2 – a u O N O R S , o u r D Up to $499 Drs. David & Lois Hinman Professor Charlotte & Mr. Norman Otto Abbott Laboratories Dr. Peter & Mrs. Catherine Hodder Mr. Benjamin Paulson Mr. Ronald Aley & Mrs. Joy Jackson Ms. Marilyn Hoekstra Mr. Ralph & Dr. Mary Peak Ms. Carolyn Allen Mr. Tom Hom & Ms. Mae Rosok Dr. Douglas & Mrs. Joyrene Perkins American International Group Mr. Benjamin Horst Mr. David & Mrs. Jean Plummer Miss Serine Avagyan Mr. William & Mrs. Carole Howald Dr. Herbert & Mrs. Letitia Portelance Dr. James & Mrs. Diane Baker Dr. Heman & Mrs. Rhea Hunt Mr. Thomas & Dr. Marybeth Porter Jr. Mr. Jack & Mrs. Carol Baush Mr. John Hunter Dr. John & Mrs. Margaret Powell Mrs. Ruth & Dr. Theodore Beck Mr. John & Ms. Barbra Hyman Professor Philip & Mrs. Diane Proteau Dr. Roy & Mrs. Ione Behm Dr. Arthur & Mrs. Glenda Israel Dr. Catherine Radzewich Mrs. Ruby & Dr. Alvin Beilby Professor Judith Jaehning & Dr. David Reichgott Mr. Simon Bennett Mr. Barry Solisky Dr. Stacia & Mr. Robert Rink Dr. James & Ms. Debra Billigmeier Drs. Natarajan Janarthanan & Mr. Daniel Ritter Mr. Cornelius & Mrs. Catherine Borman Ponni Rajagopal Dr. Janis & Mrs. Brigita Robins Professor Wendy & Mr. Charles Boss Dr. Lewis Johnson Mr. David & Mrs. Marti Robinson Mr. George Bouchard Ms. Elizabeth Kim Mrs. Judith & Mr. Richard Robinson Brookside East Apartments Mr. Fred & Mrs. Terri Krick Mr. Harry & Mrs. Inge Roegner Dr. Bruce Brown Dr. Gary & Ms. Marian Lampman Dr. Fuqiang Ruan & Ms. Qinxiao Zhou Ms. Margaret Brown Dr. Lynn & Mrs. Bette Larsen Dr. Mark & Mrs. Jill Rueber Dr. Bruce & Mrs. Aimee Buchanan Dr. George & Mrs. Jeanne LeClercq Dr. Arnold & Mrs. Susan Schaffer Mrs. Ann & Mr. Carl Cady Dr. Gregory Lee Drs. Paul & Beth Schomber Dr. Howard & Mrs. Joyce Cady Ms. Linda Leinicke Mr. Brett Schrom Mr. Bernard Carlsen Mr. Jameson Leong Dr. Pamela Seaton Mr. Kenneth Clark & Dr. Paul & Mrs. Jean Lepse The Seattle Foundation Mrs. Hasmig Seropian Dr. Yueh-Neu Lin Dr. David & Mrs. Aruni Shapiro ConocoPhillips Company Dr. Wesley & Mrs. Merrilyn Lingren Drs. Barbara & Robert Shaw Jr. Dr. Roy & Mrs. Mabelan Correa Jr. Lockheed Martin Corporation Dr. John & Mrs. Celeste Shibata Mr. David Cullen Dr. Franklin Looney Jr. Dr. Rodney & Mrs. Ruth Sime Professor Douglas & Mrs. Christine Davis Ms. Janet Lund Ms. Amanda & Dr. Parikhit Sinha Dr. Alan & Ms. Esther Denniston Dr. Max Lustig Mr. James & Mrs. Judy Sonnett Dr. Thomas & Mrs. Sara Dorn Professor James Mayer & Ms. Faith Katkin Dr. Kenneth & Mrs. Nancy Spitzer Dow Chemical Company Ms. Theresa McBride Dr. John & Mrs. Christie Stein Mrs. Allyson & Mr. Jesse Eichner Dr. Layton & Mrs. Elizabeth McCoy Dr. Bernice Stewart Mr. Tuck Eng Mr. William & Mrs. Nancy McDonald Dr. Virginia Stout & Drs. Jurgen & Mary Exner Microsoft Corporation Mr. P. William Sieverling Jr. Dr. Edmond & Mrs. Cathy Fey Drs. Theodore & Janice Mill Mr. Lowell Thomson Dr. John Freeman Drs. Cindy Mitch-Gomez & Mrs. Carolyn & Dr. Louis Torre Professor Cameon & Mr. William Geyer Alvaro Gomez Mr. Thomas Van Zandt Dr. Milton & Mrs. Marion Goheen Dr. Jovan & Mrs. Anne Moacanin Dr. Mark Voges & Dr. Elizabeth & Mr. David Goldberg Drs. Alexander & Ann Motten Ms. Mary Huggins-Voges Professor Martin Gouterman Mrs. Cynthia & Mr. Darryl Nakamura Dr. William & Mrs. Margaret Wacholtz Mrs. Shirley & Dr. John Gray Dr. Jeffrey & Mrs. Melissa Nelson Dr. Kenneth & Mrs. Lynn Ward Dr. Edmond & Mrs. Rebecca Green Dr. Jerry Nelson Dr. John & Mrs. Rosana Warren Mr. Larry & Mrs. Shirley Grossman Drs. Richard Norman & Anne True Mr. Grant Webster Mrs. Melody & Mr. Thomas Haff Dr. James & Mrs. Marcia Nusz Mr. Donald & Mrs. Marilyn Whitford Dr. Louis & Ms. Arlene Hahn Dr. Kent & Mrs. Susan Oakes Dr. Richard & Mrs. Sophia Wilde Mr. Robert Hall Mr. Carl & Mrs. Cynthia Oda Mr. Drew & Mrs. Susan Williams Dr. Robert Hammer Mr. Emery & Mrs. Sonja Ojala Dr. Jean Woller Dr. Edward & Mrs. Arlene Hardwidge Dr. Warren & Ms. Susan Oldham Jr. Dr. Robert & Mrs. Patsy Woodley Dr. William Harrison Mrs. Elizabeth & Mr. Roger Olleman Dr. Glen & Ms. Nancy Wurden 2013 autumn

Mr. Cecil Harsh Ms. A. Zin Oo Mr. Arthur Yoshimura Dr. Gary & Ms. Barbara Hickernell Dr. Donna Oswald Dr. George Zakrzewski ChemLetter 15 Nonprofit Org. University of Washington U.S. Postage Department of Chemistry PAID Seattle, WA Box 351700 Permit No. 62 Seattle, WA 98195-1700

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ChemLetter new chemistry Endowment Endowed Fund established in memory published by Department of Chemistry of Bruce Kowalski University of Washington The Department of Chemistry is pleased to Courtesy of Sandy Torgeson Paul B. Hopkins, Chair announce the establishment of the Bruce R. Bruce Kowalski Robert E. Synovec, Associate Chair Kowalski Endowed Fund in Chemistry. The fund for Graduate Studies will be used to foster innovations in research or Gary Drobny, Associate Chair for Undergraduate Studies educational programs in the chemical sciences. In honor of its namesake, the Department will match Deborah Wiegand, Director of Make a gift to Entry-Level Programs gifts made to the fund until December 31, 2014, this fund in one totaling up to $25,000 of matching funds. Contributors Bruce R. Kowalski was a luminary in the field of two ways: Jasmine Bryant, Lecturer of analytical chemistry. He served on the faculty 1. Complete the Diana Knight, Assistant to the Chair of the Department of Chemistry at the University form on the enclosed Cathy Schwartz, Graphic Designer of Washington, Seattle, from 1974 until his retire- envelope with your ment in 1999. Kowalski is best known for his credit or debit card contributions as a pioneer in the field of chemo- Printed on recycled paper using number. Write metrics, a technique that uses multivariate analysis vegetable-based inks. “Kowalski Endowed for the characterization of chemical processes. He Photo in masthead: Jupiterimages/ Fund” anywhere on photos.com was the founding Director of the National Science the form. Printed on recycled paper Foundation-funded Center for Process Analytical using vegetable-based inks. Chemistry, a highly successful university–industry 2. Mail a check or cooperative venture. money order in the Become our fan! You may recall reading of Kowalski’s passing in www.facebook.com/UWChem enclosed envelope. the Spring ChemLetter. Kowalski is deeply missed Write “Kowalski autumn 2013 autumn

We want to know what you’ve by his faculty colleagues in the Department of Endowed Fund” on been up to! Chemistry. He is remembered as a person of great the memo line. Please send your comments ability, creativity, and enthusiasm. and updates to: The fund launched on October 1, 2013. [email protected] ChemLetter 16