May 26, 2010 Sincerely, Cynthia J. Burrows Distinguished Professor Chair, 2010 COV For
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The Case for Convergence [Entire Talk]
Stanford eCorner The Case for Convergence [Entire Talk] Joseph DeSimone, Carbon 01-07-2020 URL: https://ecorner.stanford.edu/videos/the-case-for-convergence-entire-talk/ Joe DeSimone is the founder and executive chairman of Carbon, a global company that is driving the evolution of 3D printing from a prototyping tool into a scalable manufacturing technology. As a professor at the University of North Carolina, DeSimone made scientific breakthroughs in areas including green chemistry, medical devices, and nanotechnology, also co-founding several companies based on his research. In 2016 President Obama awarded him the National Medal of Technology and Innovation, the highest honor in the U.S. for achievement and leadership in advancing technological progress. In this talk, he explores how diverse teams, perspectives and specialties can drive innovations in both technologies and business models. Transcript Presenter Who you are, defines how you built.. 00:00:08,890 - We're welcoming back, Joe.. 00:00:13,330 Who was here, of just, almost four years ago in 2016.. He co-founded Carbon three years before that.. Previously, he was professor at university of North Carolina, but while you were there, you were also, you do these scientific breakthroughs like I mentioned, in co- founding several companies, all before launching Carbon.. So can you share a little bit more about that path and how you balance those two? - Well, sure.. 00:00:40,840 It's great to connect with a Dukie here, as a Tar Heel but, in fact my first PhD student, Valerie Ashby is now Dean of Trinity college at Duke university. -
Preparation and Characterization of Iridium Hydride and Dihydrogen Complexes Relevant to Biomass Deoxygenation
Preparation and Characterization of Iridium Hydride and Dihydrogen Complexes Relevant to Biomass Deoxygenation Jonathan M. Goldberg A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy University of Washington 2017 Reading Committee: D. Michael Heinekey, Chair Karen I. Goldberg, Chair Brandi M. Cossairt Program Authorized to Offer Degree: Department of Chemistry © Copyright 2017 Jonathan M. Goldberg University of Washington Abstract Preparation and Characterization of Iridium Hydride and Dihydrogen Complexes Relevant to Biomass Deoxygenation Jonathan M. Goldberg Chairs of the Supervisory Committee: Professor D. Michael Heinekey Professor Karen I. Goldberg Department of Chemistry This thesis describes the fundamental organometallic reactivity of iridium pincer complexes and their applications to glycerol deoxygenation catalysis. These investigations provide support for each step of a previously proposed glycerol deoxygenation mechanism. Chapter 1 outlines the motivations for this work, specifically the goal of using biomass as a chemical feedstock over more common petroleum-based sources. A discussion of the importance of transforming glycerol to higher value products, such as 1,3-propanediol, is discussed. Chapter 2 describes investigations into the importance of pincer ligand steric factors on the coordination chemistry of the iridium metal center. Full characterization of a five-coordinate iridium-hydride complex is presented; this species was previously proposed to be a catalyst resting state for glycerol deoxygenation. Chapter 3 investigates hydrogen addition to R4(POCOP)Ir(CO) R4 3 t i R4 R4 3 [ POCOP = κ -C6H3-2,6-(OPR2)2 for R = Bu, Pr] and (PCP)Ir(CO) [ (PCP) = κ -C6H3-2,6- t i (CH2PR2)2 for R = Bu, Pr] to give cis- and/or trans-dihydride complexes. -
Examining the Technology for a Sustainable Environment Grant Program
Examining the Technology for a Sustainable Environment Grant Program An Interactive Qualifying Project Report Submitted to the Faculty of WORCESTER POLYTECHNIC INSTIUTE In partial fulfillment of the requirements for the Degree of Bachelor of Science Submitted to: Professor James Demetry Professor Joseph Petruccelli Worcester Polytechnic Institute: Washington, D.C. Project Center By: Eddie Diaz _____________________ Melissa Hinton _____________________ Mark Stevenson _____________________ December 13, 2004 In Cooperation with the Environmental Protection Agency Diana Bauer, Ph.D April Richards, PE National Center of National Center of Environmental Research Environmental Research Environmental Protection Environmental Protection Agency Agency Washington, DC 20005 Washington, DC 20005 This report is submitted in partial fulfillment of the degree requirements of Worcester Polytechnic Institute. The views and opinions expressed herein are those of the authors and do not necessarily reflect the positions or opinions of the Environmental Protection Agency or Worcester Polytechnic Institute. Abstract This project was performed with the support of the Environmental Protection Agency and involved the examination of the Technology for a Sustainable Environment (TSE) grants program. We selected ten researchers funded by the TSE program, interviewed them, and reviewed their research in terms of qualitative and quantitative academic, industrial, and potential environmental impacts. For each of the ten researchers, we wove this information together -
Melanie S. Sanford
Melanie S. Sanford Department of Chemistry University of Michigan Ann Arbor, MI 48109 Tel. (734) 615-0451 Fax (734) 647-4865 [email protected] Research Group: http://www.umich.edu/~mssgroup/ EDUCATION: Ph.D., Chemistry June 2001 California Institute of Technology, Pasadena, CA Thesis Title: Synthetic and Mechanistic Investigations of Ruthenium Olefin Metathesis Catalysts B.S.; M.S. cum laude with Distinction in Chemistry June 1996 Yale University, New Haven, CT CURRENT POSITION: University of Michigan, Ann Arbor, MI Moses Gomberg Distinguished University Professor of Chemistry September 2016 – present Arthur F. Thurnau Professor of Chemistry July 2011 – present PREVIOUS POSITIONS: University of Michigan, Ann Arbor, MI Moses Gomberg Collegiate Professor of Chemistry January 2012 – Sept 2016 Professor of Chemistry September 2010 – June 2011 Associate Professor of Chemistry May 2007 – August 2010 William R. Roush Assistant Professor of Chemistry October 2006 – May 2007 Assistant Professor of Chemistry July 2003 – October 2006 Princeton University, Princeton, NJ NIH NRSA Postdoctoral Fellow August 2001 – June 2003 Advisor: Professor John T. Groves California Institute of Technology, Pasadena, CA Graduate Student August 1997 – July 2001 Advisor: Professor Robert H. Grubbs Yale University, New Haven, CT Undergraduate Student September 1994 – June 1996 Advisor: Professor Robert H. Crabtree Naval Research Laboratory, Washington, DC Summer Intern Summer 2003, 2004, 2005 Advisor: Dr. David W. Conrad AWARDS: Honorary Doctorate, University of South -
Letter from the Chair
CHEMLETTERSPRING 2017 / VOLUME XXXV NO. 1 LETTER FROM THE CHAIR Dear Friend of Chemistry, Greetings from the chair’s office to all of our alumni and friends. We do not yet know the As you read this, Spring Quarter is drawing to a close and we are details of our state budget, preparing our graduation ceremonies for the Class of 2017. Our but we anticipate continued students have made us proud again this year. Our department modest support. Thus we is strongly represented in the second cohort of the Husky 100, depend more than ever on by five students who have been recognized for their passion and the generosity of our donors leadership in applying what they learn on campus in ways that to provide the funds which make a difference in their communities and for the future. make excellence feasible. I am deeply gratified to report This is the time of year when we are working hard to recruit that Larry Dalton and Nicole graduate students to join us in September. I am pleased to report Boand have made a very that we will welcome 45 new students in the fall. This class of 21 generous commitment to the Department. This transformative gift women and 24 men comes from top universities in the U.S. (39) is described in greater detail on page 4. and abroad (6). We are always energized by the arrival of a new cohort of bright young people who bring great enthusiasm to their Thank you to all of our supporters; your annual gift of even $10 research and teaching. -
In This Issue I Am Pleased to Report a Landmark Event
Autumn 2013 ChemLetter Volume XXXI • No. 4 Dear Friend of Chemistry, Greetings from UW Chemistry! I hope this edition of the ChemLetter finds you and yours well. It is my pleasure to provide this update on our activities. In this era of rising student demand for science coursework, each successive year brings record-breaking enrollment levels in our courses. To provide a sense of scale, a few more than 6,000 students started as freshmen this year at the UW; our fall quarter enrollment in freshman-level chemistry classes was over 3,000! Nearly 2,000 students are presently enrolled in just one course, CHEM 142, first quarter chemistry for those Nancy Wade Nancy who enter with a high school-level chemistry background. When I began as department chair, enrollment in this course was just half this number. I am glad no one told me Paul Hopkins, Chair Wade Nancy that on my watch enrollment in this resource-intensive course, which was already our largest, would double. At the other end of this “student pipeline” are the many students who complete bachelor’s degrees in chemistry or biochemistry, or both. The size of this program has now stabilized at about 400 degrees per year, an unusually large number even for a large public university. In this issue I am pleased to report a landmark event. Longtime readers will know that it has been an institutional goal for a great many years to renovate to modern standards the Letter from the Chair 1 rooms in which our freshmen do their laboratory work. -
THE ASSIST CENTER NC State Is Now the Nation’S Only University Leading Two Active NSF Engineering Research Centers
FALL/WINTER 2012 THE ASSIST CENTER NC State is now the nation’s only university leading two active NSF Engineering Research Centers RISING FACULTY STARS PROBLEM-SOLVING SENIOR PROJECTS ADVICE FROM AMELIA Katharine Stinson’s barrier-breaking engineering career Just one year and a whopping 48 credit hours later, she started in 1932 on the dusty runway of her hometown marched back to NC State. She graduated in 1941 with a airstrip. BS in mechanical engineering with an aeronautics option, becoming the first woman to leave the university with an Legendary flyer Amelia Earhart (above right) had engineering degree. touched down at the old Raleigh Municipal Airport, and the 15-year-old Stinson stole a moment with her idol to Stinson spent the next 32 years with the US Civil share her dream of becoming a pilot. But pilots didn’t Aeronautics Administration (now the Federal Aviation make much money in those days, and Earhart suggested Administration) making key contributions to aircraft another occupation. safety. She even served on an advisory committee under President Lyndon Johnson. “Don’t become a pilot, become an engineer,” Stinson recalled her saying. But Stinson never forgot her NC State roots, and the university never forgot her. She became the first woman Stinson (above left) took the advice. But when she to serve on the Alumni Association Board of Directors and applied to NC State a few years later, she hit a roadblock: earn recognition as a Distinguished Engineering Alumna. Women weren’t allowed to study engineering at the university. To give other women similar opportunities, she established the Katharine Stinson Scholarships for Stinson persisted, convincing the dean of engineering to Women in Engineering in 1987. -
Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses Jason E
Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses Jason E. Coffman,† Stefan W. Metz,‡ Alex Brackbill,§ Molly Paul,∥ Michael J. Miley,§ Joseph DeSimone,†,∥,⊥ J. Christopher Luft,# Aravinda de Silva,‡ and Shaomin Tian*,‡ † Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27607, United States ‡ § ∥ ⊥ Department of Microbiology and Immunology, Department of Pharmacology, Department of Chemistry, Lineberger # Comprehensive Center, and Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States ABSTRACT: The dengue virus (DENV) causes over 350 million infections, resulting in ∼25,000 deaths per year globally. An effective dengue vaccine requires generation of strong and balanced neutralizing antibodies against all four antigenically distinct serotypes of DENV. The leading live- attenuated tetravalent dengue virus vaccine platform has shown partial efficacy, with an unbalanced response across the four serotypes in clinical trials. DENV subunit vaccine platforms are being developed because they provide a strong safety profile and are expected to avoid the unbalanced immunization issues associated with live multivalent vaccines. Subunit vaccines often lack immunogenicity, requiring either a particulate or adjuvanted formulation. Particulate formulations adsorbing monomeric DENV-E antigen to the particle surface incite a strong immune response, but have no control of antigen presentation. Highly neutralizing epitopes are displayed by DENV-E quaternary structures. To control the display of DENV-E and produce quaternary structures, particulate formulations that covalently attach DENV-E to the particle surface are needed. Here we develop a surface attached DENV2-E particulate formulation, as well as analysis tools, using PEG hydrogel nanoparticles created with particle replication in nonwetting templates (PRINT) technology. -
Chemistry Biochemistry
Chemistry & Biochemistry VOLUME 4 NUMBER 1 LAFAYETTE Spirng 2008 hospital to develop cheaper, less toxic antiretroviral treatments to Freedman ’08 and Vasta ’10 ease the suffering and extend the lives of HIV-positive patients. He did research on gamma-hydroxy butenolides as an EXCEL Scholar with Awarded Goldwater Professor William Miles and an honors thesis under the direction of Scholarships Assistant Professor Yvonne Gindt. He also was a standout performer on the varsity swim team for four years. Jaryd Freedman ’08 and James Vasta ’10 are the latest biochemistry Vasta, awarded the Goldwater this year, majors to receive the Goldwater Scholarship, the nation’s premier plans to obtain a doctorate in biochemistry. The Goldwater is undergraduate award in math, science, and engineering. He would like to conduct research in the nation’s premier Freedman, a 2007 Goldwater recipient, plans to obtain an M.D. and biochemistry and metabonomics and teach Ph.D. in biochemistry. He would like to conduct research at a university at the university level. Last summer, he did undergraduate EXCEL research using high performance thin award in math, layer chromatography under the guidance of science, and Joseph Sherma, Larkin Professor Emeritus engineering. With of Chemistry, and Bernard Fried, Kreider 16 recipients in Professor Emeritus of Biology. the last seven Vasta’s essay on the significance of Grignard years, Lafayette is reagents in organic chemistry was the winner unmatched by any of a $1,000 scholarship competition sponsored other exclusively by the Lehigh Valley Section of the American undergraduate Chemical Society. liberal arts and In the last seven years, five biochemistry engineering college. -
Table of Contents University of Rochester Department of Chemistry 404 Hutchison Hall RC Box 270216 Chemistry Department Faculty and Staff Rochester, NY 14627-0216 3
CONTACT ADDRESS Table of Contents University of Rochester Department of Chemistry 404 Hutchison Hall RC Box 270216 Chemistry Department Faculty and Staff Rochester, NY 14627-0216 3 PHONE 4 Letter from the Chair (585) 275-4231 6 Donors to the Chemistry Department EMAIL 10 Alumni News [email protected] Esther M. Conwell receives National Medal of Science WEBSITE 14 http://www.chem.rochester.edu 16 A Celebration in Honor of Richard Eisenberg 18 Department Mourns the Loss of Jack Kampmeier CREDITS 20 Xiaowei Zhuang receives the 2010 Magomedov- EDITOR Shcherbinina Award Lory Hedges 21 Joseph DeSimone receives for 2011 Harrison Howe LAYOUT & DESIGN EDITOR John Bertola (B.A. ’09, M.S. ’10W) Award Lory Hedges 22 Chemistry Welcomes Michael Neidig REVIEWING EDITORS Kirstin Campbell 23 New Organic Chemistry Lab Lynda McGarry Terrell Samoriski 24 The 2011 Biological Chemistry Cluster Retreat Barb Snaith 26 Student Awards and Accolades COVER ART AND LOGOS Faculty News Breanna Eng (’13) 28 Sheridan Vincent 60 Faculty Publications WRITING CONTRIBUTIONS 66 Commencement 2011 Department Faculty Lory Hedges 68 Commencement Awards Breanna Eng (’13) Terri Clark 69 Postdoctoral Fellows and Research Associates Select Alumni 70 Seminars and Colloquia PHOTOGRAPHS UR Communications 74 Staff News National Science & Technology Departmental Funds Medals Foundation 79 John Bertola (B.A. ’09, M.S. ’10W) 80 Alumni Update Form Karen Chiang Ria Casartelli Sheridan Vincent Thomas Krugh 1 2 Faculty and Staff FACULTY RESEARCH PROFESSORS BUSINESS OFFICE Esther M. Conwell Anna Kuitems PROFESSORS OF Samir Farid Randi Shaw CHEMISTRY Diane Visiko Robert K. Boeckman, Jr. SENIOR SCIENTISTS Doris Wheeler Kara L. -
The Michael Baird Lecture Series Was Established Zeitler, H
The Michael Baird SELECTED RECENT Lecture Series PUBLICATIONS The Michael Baird Lecture Series was established Zeitler, H. E.; Kaminsky, W. A.; Goldberg, K. in 2017, the Golden Anniversary of Mike’s arrival I. “Insertion of Molecular Oxygen into the Metal– at Queen’s, through generous donations from Methyl Bonds of Platinum(II) and Palladium(II) 1,3- former students. Bis(2-pyridylimino)isoindolate Complexes.” Organometallics 2018, 37, 3644-3648. Mike was raised in Dundas, Ontario, and obtained The Department of Chemistry, an Hon. B.Sc. in Chemistry from McMaster Stevens, T. E.; Smoll, K. A.; Goldberg, K. I. “Direct Queen’s University 3 University (where he also won several OUAA and Formation of Carbon(sp )-Heteroatom Bonds from CIS intercollegiate sprint championships). He RhIII to Produce Methyl Iodide, Thioethers, and is honoured to host the completed his Ph.D. within three years at the Alkylamines.” J. Am. Chem. Soc. 2017, 139, 7725- 2018 Baird Lecture: University of Toronto, and then spent two 7728. extremely productive postdoctoral years with Sir Geoffrey Wilkinson (1973 Nobel Prize) at Imperial Gao, Y.; Guan, C.; Zhou, M.; Kumar, A.; Emge, T.; Wright, A. M.; Goldberg, K. I.; Krogh-Jespersen, Karen I. Goldberg College, London. He joined the faculty at Queen’s University of Pennsylvania in 1967. K; Goldman, A. S. “ β-Hydride Elimination and C-H Activation by an Iridium Acetate Complex, Mike has carried out research on many aspects of Catalyzed by Lewis Acids. Alkane “Molecular Oxygen as a organometallic chemistry and catalysis, publishing Dehydrogenation Co Catalyzed by Lewis Acids Reagent in Late Transition over 275 papers and ten patents. -
Letter from the Chair
CHEMLETTERAUTUMN 2017 / VOLUME XXXV NO.3 LETTER FROM THE CHAIR Dear Friend of Chemistry, Since my last message to you, we have begun the new academic year, with continuing increases in undergraduate enrollment. To help us to teach these large numbers of undergraduates, we rely on the contributions of our graduate students, who serve as teaching assistants. The incoming cohort of graduate students for the 2017- 18 academic year consists of 44 students: 22 women and 22 men from top universities in the U.S. (39) and abroad (5). To recruit this group, our faculty carefully reviewed more than 600 applications from all over the world. Students are attracted to our program by the caliber of the faculty with whom they would study, the UW’s tradition of excellence, and the quality of life in the Seattle area. We have implemented a new rotation system for our first-year graduate students to get acquainted with the work and culture of research groups they may be interested in joining. The rotation at the level of $2.6 million per year for six years. This initiative will is meant to facilitate students finding a good fit with their Ph.D. enhance the strong presence of the UW in the field of materials advisor, for which the selection process will take place next quarter. science, with an emphasis on the development of nanoscale electronic materials for numerous applications, from spectral The research program to which these students will contribute conversion to spintronics. Adjunct Associate Professor Christine continues to prosper. Our faculty have been very successful in Luscombe is the co-PI and Professors David Ginger, Xiaosong Li, winning highly competitive grants to support this work from a and Assistant Professor Brandi Cossairt are participants.