Copy of Experience

Total Page：16

File Type：pdf, Size：1020Kb

PROLACTIN & DLS Science Cafe ANGIOGENESIS: SPECIAL LECTURE SIGNIFICANCE OF SERIES MICROHETEROGENEITY Prof. Muralidhar has contributed significantly to biomedical sciences in the area of Biochemical Endocrinology. He has received numerous recognitions including fellowships from three major science academies. He is an outstanding and innovative teacher and has contributed to strengthening of all levels of biology education Prof. Muralidhar Kambadur from schools to universities. Prof. Muralidhar has assisted NCERT in bringing out new text JN Chair Professor books in biology for Class XI and XII, which University of Hyderabad have have been adopted by the CBSE for use across schools in the country. At the UG level, he has assisted the University of Delhi in formulating and piloting the academic bodies Organized by and is the Co-Chairman of SRF program Department of Life Sciences initiated by IASc, Bengaluru. At the PG level he Central University of Tamil Nadu has been the Chairman of the Curriculam Development Committee of UGC. He has also Thiruvarur, India been a member of Examination Board of AIIMS for setting question papers for MBBS and MSc entrance exams. He has guided more than 50 Pro-VC PhD students and 3000 PG students, and also Chamber has 35 years of teaching experience. Prof. CUTN Muralidhar is currently serving many funding 29th Nov agencies and has been promoting science 10am enormously across the country. Prolactin and Angiogenesis-Significance of Micro-heterogeneity Kambadur Muralidhar JN Chair, School of Life sciences University of Hyderabad Email: [email protected] Abstract Prolactin (PRL) or Mammotropic hormone (MH) exhibits structural micro heterogeneity. The native hormone purified from buffalo pituitaries comprises size and charge isoforms. The isoform with higher pI (basic form) was found to possess higher bio potency in Nb2 rat lymphoma cell line growth assay the acidic isoform. The full length 22kDa isoform also had the full bio potency. Prolactin is known to produce more than 300 effects in vertebrates from fish to mammals. In order to understand this further, and to form a frame work for investigations, two hypotheses were proposed. One, that micro heterogeneous forms of prolactin should exhibit differential potency in a given bioassay during ontogeny. Two, that micro heterogeneous forms of Prolactin should exhibit different biological activities during phylogeny. Buffalo pituitary PRL was purified to homogeneity from freshly frozen pituitaries and characterized extensively. The cDNA corresponding to buffalo PRL was cloned and expressed as inclusion bodies in E.coli. The gene product was renatured and purified to homogeneity. It was as active as native hormone, if not more, in cell line based bioassay. It did not exhibit micro heterogeneity. Lower size isoforms of native PRL exhibited antiangiogenic activity in CAM assay. Intact PRL did not possess this activity. When the 22kDa intact PRL monomer was digested with Cathepsin D a number of fragments were obtained. The 14-kDa fragment exhibited anti-angiogenic activity in CAM assay, cell migration inhibition assay and wound healing assay.The amino acid sequence of buPRL monomer was deduced from cDNA nucleotide sequence. .

Copy Link

Recommended publications

Frontier Lectures in Biology
In the year 2012, INSA initiated a program called “INSA-100 Lectures” to enable INSA Fellows to visit remote instiutions, schools, colleges and Universities and deliver popular lectures that will not only deal with contemporary developments in the field but also inspire the students and teachers who are deprived of exposure to higher institutions of learning. Frontier Lectures In Biology By INSA Fellows Editor S. K. Saidapur FNA Table of Contents Section 1: General Biology ........................................................................................................................... 4 Biology: Its Past, Present & Future ........................................................................................................... 5 S. K. Saidapur ......................................................................................................................................... Discoveries leading to Innovations For Mankind ...................................................................................... 8 V P.Kamboj ............................................................................................................................................ Growth in Childhood and Adolescence .................................................................................................. 19 K. N. Agarwal ........................................................................................................................................ Nature of Science and Biology Education ..............................................................................................
[Show full text]
Seminar Disquisition
AIFUCTO XXVII Statutory Conference, 2013 z November 30, December 1 & 2, 2013 z Loyola Hall, St Aloysius College, Mangalore SEMINAR DISQUISITION “CHANGING PARADIGMS OF HIGHER EDUCATION XII FIVE YEAR PLAN INITIATIVES” SPONSORED BY NATIONAL UNIVERSITY OF EDUCATIONAL PLANNING AND ADMINISTRATION (NUEPA) Edited by : Dr. Denis Fernandes ASSOCIATION OF MANGALORE UNIVERSITY COLLEGE TEACHERS (AMUCT) Seminar Disquisition 1 XXVII AIFUCTO STATUTORY CONFERENCE, 2013 ORAGNISING COMMITTEE A: ORAGNISING COMMITTEE 1. Chief Patron: Prof T. C. Shivashankar Murthy, Hon’ble Vice Chancellor, Mangalore University 2. Patron : Rev. Fr. Denzil Lobo, Rector, St. Aloysius Institutions, Mangalore 3. Conference Chairman : Dr A. M. Narahari, Former President AMUCT & FUCTAK 4. Oraganising Secretary : Dr Norbert Lobo, President, AMUCT 5. Conference Treasurer : Mr Charles Pais, Treasurer, AMUCT MEMBERS: 6. Prof.Tarun Kumar Patra : President, AIFUCTO: ( All India Federation of University and College Teachers Organisation) 7. Prof.Ashok Barman : General Secretary, AIFUCTO 8. Prof.Nikhil Desai: Treasurer, AIFUCTO 9. Mr L.R. Angady: Zonal Secretary, SE Zone, AIFUCTO 10. Mr C.H.Murigendrappa: President, FUCTAK (Federation of University and College Teachers University Associations in Karnataka) 11. Mr K.M.Nagaraj: General Secretary, FUCTAK 12. Mr Manjunath T.M: President, KGCTA (Karnataka Government College Teachers Association) 13. Mr Bhagyavan M.: General Secretary, KGCTA 14. Dr N. B. Sangapur : President, KUCTA ( Karnataka University Private College Teachers Association 15.
[Show full text]
NUGGEHALLI RAGHUVEER MOUDGAL (4 March 1931 - 8 May 2011)
NUGGEHALLI RAGHUVEER MOUDGAL (4 March 1931 - 8 May 2011) Biog, Mem. Fell. INSA, New Delhi 40 (2013) 57-74 NUGGEHALLI RAGHUVEER MOUDGAL (1931-2011) Elected Fellow 1978 PERSONAL LIFE UGGEHALLI RAGHUVEER MOUDGAL was born on 4th March, 1931 in N Mysore, Karnataka in an upper middle class family. His father, N Narasimha Moudgal was the Chief Electrical Engineer, Mysore State Electricity Board and was largely responsible for the electrification of the state. His mother, Vaidehi Moudgal was a home maker and had tremendous influence on her children as she was artistic and very tidy and organized in her daily activities. He belonged to a community called 'Hebbar Iyengars' who speak at home a dialect which is a mixture of Kannada and Tamil. NR Moudgal was the youngest of five children-three boys and two girls. He adored his two elder brothers, N Shyam Prasad and N Ram Prasad. His two sisters, Prabha Devi Anantram and Harini Madhava Rao were close to him. The latter got him interested in reading classic English literature at an early age and he completed High School in 1946 in Seshadripuram High School, Bengaluru. He stayed with Prabha Devi's family at Bhavnagar and Kolhapur during his college days. This led to a B.Sc degree in 1950 from the University of Bombay. Moudgal, like other young people of his generation went to Madras to obtain his MSc by research in 1954, working on biochemistry of thyroid hormones. He married Prapulla nee Biligiri Rao on 20th May, 1957. His wife Prapulla passed away on December 10,2008.
[Show full text]
Biology Education, Creativity & Career
International Journal of Applied and Natural Sciences (IJANS) ISSN 2319-4014 Vol. 2, Issue 2, May 2013, 53-64 © IASET BIOLOGY EDUCATION, CREATIVITY & CAREER KAMBADUR MURALIDHAR Hormone Research Laboratory, Department of Zoology, University of Delhi, Delhi, India ABSTRACT The growth of biological thought during the last 500 years has been analyzed conceptually in the context of education at school, undergraduate and post graduate levels. Again in the context of creativity, the near absence of creativity in the Indian scientific enterprise has been explored and the factors which contribute to that have been discussed. The natural goal of biology would be Human Biology which will bring back creativity while it is being pursued. Biology would become the most fascinating frontier of all natural sciences in near future. What does it mean to have a successful career in Biology has been explained. Career opportunities in India for young people having aptitude for Biology have been discussed. KEYWORDS: Biology Education, Creativity, Human Biology, Career in Biology INTRODUCTION Education Education should liberate the young mind from false perceptions and values. It should enable the human mind think for itself. It should bring forth a mind-set of reflective mood. Education should empower each human consciousness to reach its highest level [1]. The goals of higher education were different in the colonial era when compared to those for the post-Independent India These were spelt out clearly by Jawaharlal Nehru and in the reports of both Sir Radhakrishnan and Prof DS Kothari led education commissions. Even these have undergone changes in the post-globalization era.
[Show full text]
Science Education, Research
Ethics in Science Education, ETHICS IN SCIENCE EDUCATION, RESEARCH AND GOVERNANCE RESEARCH ETHICS INSCIENCEEDUCATION, Research and Governance As has been articulated multiple times, Ethics is all about the respect for other person’s rights and a responsibility for one’s own conduct. This book on Ethics in Science Education, Research and Governance is amongst the ﬁ rst attempts in India, to put together, basic tenets and moral principles, that ETHICS may guide the behavior and conduct of anyone connected with science, in a responsible manner. This book builds on several in scholarly articles and thematic publications on Ethical conduct SCIENCE EDUCATION, in Science. This book evolved out of of serious deliberations by RESEARCH AND GOVERNANCE several accomplished and acclaimed professionals and media experts with long experience in their professions. It comprises nine chapters dealing with various aspects, covering a broad spectrum of issues in Science and its practice – science education, ethics, outreach, gender issues and Governance. Edited by The Editors are academicians with a total of over 120 years K Muralidhar of combined experience in the practice of science. They hope that this compilation will provide minimalistic leitsaetze for Amit Ghosh the practitioners of Science. They also hope that this book is AK Singhvi the ﬁ rst step towards the evolution of a more comprehensive compendium. The book is being published by the Indian National Science Academy (INSA), which is designated by the Government of India to represent it in all international fora. This is a part of INSA’s basic vision of nurturing and supporting excellence in L SCIE NA NC IO E T A A C N A science following strict ethical guidelines and is designed to N D A E I M D Y Y N N I inform lay people, practitioners of science and policy makers I about it.
[Show full text]
2016 Organized by INDIAN ACADEMY of SOCIAL SCIENCES
XL INDIAN SOCIAL SCIENCE CONGRESS- 2016 Organized by INDIAN ACADEMY OF SOCIAL SCIENCES & UNIVERSITY OF MYSORE As part of the Centenary Celebrations (1916-2016) Focal Theme PEOPLE’S HEALTH AND QUALITY OF LIFE IN INDIA National Symposium on ‘PERSPECTIVES ON LIFE SCIENCE, SOCIETY AND EMERGING TECHNOLOGIES’ SESSION I: Venue- LINNAEUS HALL, DOS in Botany, Manasagangotri. DAY 1: 19th DECEMBER 2016 TIME: 2.00 PM – 5.00 PM Sl. Time Name & Affiliation of the Speaker Topic No. 01 Invited Talk PRESIDENT’S SPEECH Ethics in Science- A Perspective 02.00PM- 2.40PM Kambadur Muralidhar Professor & Sir JC Bose National Fellow Faculty of Life Sciences & Biotechnology South Asian University, Akbar Bhawan #230 Chanakyapuri, New Delhi-110021 Email: [email protected] 02 Invited Talk R. Raghvendra Rao, Role of ethno-botany in search of newer 02.40PM- 03.20PM INSA Honorary Scientist drug plants & in conservation of biological No.328, B-4, Kendriya Vihar, Yelahanka, Bangalore-560064 diversity : some concerns & issues E-mail: [email protected] TEA BREAK 03 Invited Talk M.N.Bheemesh IP – Challenges in Life sciences 03.40PM- 04.20PM Senior Advisor, ALMT Legal, Advocates & Solicitors, Bengaluru Email: [email protected] 04 Invited Talk Rakesh Prabhu Overview of Patents in Life Sciences in 04.20PM- 05.00PM Intellectual Property Counsel and a Registered Patent Agent (IN). India Partner ALMT Legal in Bangalore. Email: [email protected] XL INDIAN SOCIAL SCIENCE CONGRESS- 2016 Organized by INDIAN ACADEMY OF SOCIAL SCIENCES & UNIVERSITY OF MYSORE As part of the Centenary Celebrations (1916-2016) Focal Theme PEOPLE’S HEALTH AND QUALITY OF LIFE IN INDIA National Symposium on ‘PERSPECTIVES ON LIFE SCIENCE, SOCIETY AND EMERGING TECHNOLOGIES’ DAY 2: 20th DECEMBER 2016 PARALLEL SESSIONS TIME: 2.00 PM – 5.00 PM SESSION I: TIME: 2.00 PM – 5.00 PM SESSION II : TIME: 2.00 PM – 5.00 PM Venue- LINNAEUS HALL, DOS in Botany Venue- SEMINAR HALL, DOS in Zoology Sl.
[Show full text]
Annual Report 2015
Untitled by Israt Farzana Tanni, MA Sociology South Asian University (A University established by SAARC nations) Akbar Bhawan, Chanakyapuri, New Delhi - 110021 (India) Phone: 91-11-24122510,12-14, Fax: (+91-11) 2412 2511 www.sau.int Annual Report 2015 ANNUAL REPORT 2015 CONTENTS From the President's Desk 01 Decision Making Bodies of SAU 03 University Finances 06 Major Highlights of the Year 07 Academic Programmes and Admissions 08 Scholarships & Financial Aid 12 University Events 14-18 Student Activities 19-21 Student Facilities and Services 22 Prof GK Chadha Library 23-24 Introduction to South Asia & English Course 25 Academic Faculties Faculty of Economics 27-33 Faculty of Legal Studies 35-43 Faculty of Life Sciences & Biotechnology 45-55 Faculty of Mathematics & Computer Science – Department of Mathematics 58-65 – Department of Computer Science 67-71 Faculty of Social Sciences – Department of Sociology 74-81 – Department of International Relations 83-89 Campus Construction 90 The theme of SAU Annual Report 2015 is "Festivals in South Asia" VISION The mandate of the South Asian University, as set out in the Agreement of the SAARC member states under which the University is set up, envisages that the choice of the programs of studies to be offered at this University should: • enhance learning in the South Asian community that promotes an understanding of each others' perspectives and strengthens regional consciousness; • provide liberal and humane education to the brightest and the most dedicated students of South Asia so that a new class of quality leadership is nurtured; and • enhance capacity building of the South Asian nations in science, technology and other areas of higher learning vital for improving their quality of life such as information technology, bio-technology and management sciences, etc.
[Show full text]
Proteases in Physiology and Pathology Sajal Chakraborti • Naranjan S
Proteases in Physiology and Pathology Sajal Chakraborti • Naranjan S. Dhalla Editors Proteases in Physiology and Pathology Editors Sajal Chakraborti Naranjan S. Dhalla Department of Biochemistry and Biophysics St. Boniface Hospital Research Centre, University of Kalyani University of Manitoba, Faculty of Kalyani, West Bengal, India Health Sciences, College of Medicine Institute of Cardiovascular Sciences Manitoba, Winnipeg, Canada ISBN 978-981-10-2512-9 ISBN 978-981-10-2513-6 (eBook) DOI 10.1007/978-981-10-2513-6 Library of Congress Control Number: 2017951624 © Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made.
[Show full text]
Medical-Sciences-Ecatalog.Pdf
Section XI: Medical Sciences (Including Physiology) 1 98th Indian Science Congress January 3-7, 2011, Chennai I PRESIDENTIAL ADDRESS President : Prof. Amar K. Chandra PRESIDENTIAL ADDRESS Thyroid Functions in Iodine Deficiency and Region Specific Environmental Goitrogens - their impact in life and society Prof. Amar K Chandra* Distinguish Scientists and Honorable Delegates from the Country and Abroad It is a great privilege and pride of mine to welcome you all in the inaugural session of the Medical Sciences (including Physiology) Section in the 98th Session of Indian Science Congress in about 350 years old city of Chennai, formerly called as Madras, the gateway to South India, and it is rich in the treasures of history from temples and shrines to forts and palaces. It is one of the largest metro cities of the country and is the major trade centre of India. The venue is at SRM University which is about 25 years old that has set outstanding standards in higher education, especially in the field of Science, Technology, Medicine and Management and thus greatly involved in shaping the higher education as dreamt by our great leaders. The topic of today’s presidential address focuses on a micronutrient iodine, one of the important environmental regulator of thyroid gland functions that regulate not only growth, development and maintenance of body functions at the different stages of life of humans and animals but intimately related with the socioeconomic development of a country. Iodine deficiency is the world’s greatest single cause of preventable brain damage and mental retardation manifesting itself as goiter and a range of physical and mental handicap, collectively included the term Iodine Deficiency Disorders (IDD).
[Show full text]
The National Academy of Sciences, India
CONFIDENTIAL (For use of Fellows of the Academy only) The National Academy of Sciences, India NOMINATIONS Valid for Consideration for Election to Fellowship – 2017 Section of Biological Sciences BOOK - II ANIMAL SCIENCES (Structural, Developmental, Functional, Genetical, Ecological, Behavioural, Taxonomical and Evolutionary Aspects) MEDICAL & FORENSIC SCIENCES (Basic and Clinical Medical Sciences, Pharmacology, Anthropology, Psychology and Forensic Sciences, Human genetics, Reproduction Biology, Neurosciences, Molecular Medicine) 5, Lajpatrai Road, Allahabad-211002 The National Academy of Sciences, India NOMINATIONS Valid for Consideration for Election to Fellowship – 2017 Section of Biological Sciences BOOK - II CONTENTS ANIMAL SCIENCES 291 - 339 (Structural, Developmental, Functional, Genetical, Ecological, Behavioural, Taxonomical and Evolutionary Aspects) MEDICAL & FORENSIC SCIENCES 340 - 437 (Basic and Clinical Medical Sciences, Pharmacology, Anthropology, Psychology and Forensic Sciences, Human genetics, Reproduction Biology, Neurosciences, Molecular Medicine) 5, Lajpatrai Road, Allahabad-211002 (I) ANIMAL SCIENCES AGRAWAL, Nirupama 307 MUKHOPADHYAY, Arnab 297 BALASINOR, Nafisa Huseni 308 NALLUR, Ramachandra Basappa 298 BANDYOPADHYAY, Probir Kumar 291 PETER, M.C. Subhash 299 BARAL, Rathindranath 309 PRAKASH, Soam 322 BHADURY, Punyasloke 292 RAISUDDIN, Sheikh 313 CHANDRA, Goutam 324 RAMACHANDRAN, Sundararaj 329 CHAUHAN, Manmohan Singh 293 RAMESH, Saraf Rajagopalaiahsetty 300 CHAUHAN, Ramswaroop Singh 325 ROY, Bishnupada 301 DAS,
[Show full text]