Manuscript CRC-Aspirin

Use of Aspirin postdiagnosis improves survival for colon cancer patients

Supplement 1: Aspirin and type of non-aspirin NSAIDs prescribed

Name Code Doses Users prediagnosis Users postdiagnosis

n=2086 n=1219 Acetylsalicyzuur B01AC06 30 mg/day (5.0%) 741 1095

80 mg/day (95%) Acetylsalicylzuur NO2BA01 300-500 mg 7 8 Indometacine M01AB01 25-100 mg 71 70 Sulindac M01AB02 100-200 mg 5 15 Diclofenac M01AB05 25-100 mg 1004 1628 Biofenac M01AB16 100 mg 14 6 Arthrotec M01AB55 50-75 mg 215 363 Piroxicam M01AC01 10-20 mg 71 24 Tilcotil M01AC02 20 mg 1 0 Meloxicam M01AC06 7.5-15 mg 247 338 Ibuprofen M01AE01 200-600 mg 627 633 Naproxen M01AE02 250-500 mg 675 947 Ketoprofen M01AE03 100-200 mg 12 5 Froben M01AE09 50-200 mg 4 4 Surgam M01AE11 200-300 mg 8 5 Seractil M01AE14 200-400 mg 8 5 Celebrex M01AH01 100-200 mg 84 229 Vioxx M01AH02 12.5-25 mg 216 259 Bextra M01AH03 20-40 mg 4 11 Arcoxia M01AH05 30-120 mg 39 132 Nabumeton M01AX01 500 mg 81 33 Prolixan M01AX04 300-600 mg 8 0 Carbasal NO2BA15 600 mg 99 58 ACCod NO2BA51 400/50/9.6 mg 24 6 Novalgin NO2BB02 500 mg 0 2

The total number adds up to more than 100% as some patients had 2 or more NSAIDs prescribed.