SCI Website Content

SCI website content

1 Colours and general layout

We would like the general layout to be the same as the IHT website but using different colours. This will provide continuity of identity but will be different enough to be viewed as a separate initiative from the IHT Programme. Hopefully it will also mean less work building the site.

To use all of the colours would probably make the site look cluttered so I suggest we choose two and then have two accent colours if needed.

The SCI logo is made up of 6 colours

Purple Pantone 2607 CVC (C70, M100) (R92, G2, B122)

Teal Pantone 3282 CVC (C100, Y45, K10) (R0, G140, B130)

Red Pantone 485 CVC (M100, Y100) (R216, G30, B5)

Orange Pantone 1375 CVC (M40, Y80) (R249, G155, B12)

Lime Pantone 390 CVC (C14, M12, Y100, K10) (R186, G196, B5)

Light Blue Pantone 310 CVC (C45, Y10) (R114, G209, B221)

We would prefer the use of the bolder colours such as the purple with a contrasting colour like the Teal. Then maybe use the red and orange again for contrast in the text or lines. I guess whatever you think works best on the screen. Below is a reminder of what you used on the IHT site.

2 The Menu Bar

 News – Similar to IHT site. On the News page we will have a link to Bulletins (similar to the Newsletters for the IHT Programme ie direct links to pdfs when they become available). Also from the News page we will need a link to another page ‘For the Media’. Bulletins and Media links/buttons will need to be at the top of the page.

 Events – same as the IHT site

 Research – this page will have multiple links leading off to the following

The Research Projects Annex 1 Genomics Centres Annex 2 International Visiting Fellowships Annex 3 Stem Cells and the Media Fellowship Annex 4 Translational Research Fellowships Annex 5

 Activities – this page will have multiple links leading off to the following

National/International Seminar Series Annex 6 Public Engagement Events Annex 7 Innovation Cafes Annex 8 ESRC Social Science Weeks Annex 9 Interdisciplinary Workshops with Stem Cell Scientists Annex 10 Methodology Workshop Annex 11 Genomics Forum 5-Day Training Course Annex 12

 Funding Opportunities – listing all activities funded by SCI office and links to pages of further info about calls once available. Annex 13

 Participants – Same as IHT. I will add to this as we go along. In the mean time please can you set up a page with the alphabet across the top with links to the relevant letter down the page and space between to add info. Thanks.

 Links – same as the IHT page. I will add stuff to this page at I go along – similar setup as IHT site with logos and links.

 Contact – as for IHT but more up to date photos!

 Search – as for IHT

 Text Only Version of Site – self explanatory

3 Introduction/Home Page Text

Please can we have the following text……

The ESRC Social Science Stem Cell Initiative (SCI) was set up in the autumn of 2005 with the broad aim of supporting a range of activities during a three-year period, to the value of £1.7million, to build research capacity and raise awareness within the UK social science community, in regard to the emerging field of Stem Cell science. The ESRC has already invested in a number of research projects (n=6) in the area (see Research link on menu bar), as well as the cross-Council support for Career Development Fellowships. The Initiative also will link to capacity building that the Genomics Centres propose to undertake, both independently, and as a network, the latter in collaboration with the Genomics Forum.

Objectives The principal strategic objective of this initiative is to build research capacity for high quality, independent social science research on Stem Cell technologies, to deepen interdisciplinary links to the biosciences, to foster translational research and activity between social science and industry, and to demonstrate and publicise the important role that ESRC work makes to the field as a whole

In achieving this objective, the Initiative aims to

 encourage a wide range of social science disciplines to engage with the field  generate interdisciplinarity across both social and natural science, especially in light of recommendations made by the current Pattison review of the area  exploit new opportunities for translational research  produce a new cohort of doctoral students and Fellows to strengthen the science base  deploy the expertise of the ESRC’s Genomics Centres in this area  anchor social science in policy-focused stem cell networks  ensure excellent media coverage of social science activity in this area  strengthen links between social science and users including the medical research, clinical, patient, health policy and commercial constituencies and  provide new opportunities to raise the profile of UK social science internationally, to contribute to and take the lead on international debate in the area.

A number of activities will take place related to both awareness raising and profiling the role of the ESRC within the wider Stem Cell field, including a series of workshops and seminars around different aspects of Stem Cell science and technology. These workshops/seminars would take different themes, draw on the wider resources of the Stem Cell Initiative, and engage national and international participants, as appropriate. Beyond the seminar series organised by the Initiative, provision will be made for competitive bids to series proposals made from the wider UK social science field, especially those that include participation from clinicians and industry.

Links to non-social science constituencies The SCI will ensure an ongoing liaison with and dissemination to various users, including the other Research Councils, government, the NHS, private corporations, medical research and patient charities, interest groups and the wider public.

4 Research

Please can we have the following text…… All underlined items to be hot linked to a new page (see Annex for contents of each of those pages)

This page lists all the research funded, or due to be funded by the SCI. Details on dates and how to apply for funding will be posted on these pages when further information becomes available.

The Research Projects Funding now closed Genomics Centres Funding now closed International Visiting Fellowships From Spring 2006 Stem Cells and the Media Fellowship From Autumn 2007 Translational Research Fellowships From Autumn 2006

Activities

Please can we have the following text…… All underlined items to be hot linked to a new page (see Annex for contents of each of those pages)

This page lists all the activities the SCI is due to run. Details on dates will be posted on these pages when further information becomes available. Information can also be found on the ‘Events’ page where non SCI run activities will also be advertised.

National/International Seminar Series From Spring 2007 Public Engagement Events From Spring 2006 Innovation Cafes From Autumn 2006 ESRC Social Science Weeks From 2007 Interdisciplinary Workshops with Stem Cell Scientists Spring 2007 Methodology Workshop Spring 2007 Genomics Forum 5-Day Training Course Spring 2008

5 Annex 1 Research Projects

Titles to be hotlinks to a new page – project pages to have same layout as IHT site ie internal links jumping to the following: Abstract, Contacts, Outputs (just those 3, not news etc). I don’t think we will be putting images on to the page – just want something simple

RES-340-25-0001 Annex 1.1 The Global Politics Of Human Embryonic Stem Cell Regulation Prof Brian Salter University Of East Anglia Dr Catherine Waldby Brunel University Expert Consultancy - Professor Herbert Gottweis University of Vienna Expert Consultancy - Dr Stephen Minger Kings College London

RES-340-25-0002 Annex 1.2 Forgotten Fetuses - A Sociocultural Analysis Of The Use Of Fetal Stem Cells Dr Julie Kent University Of The West Of England, Bristol Prof Naomi Pfeffer London Metropolitan University Prof Wendy Purcell Univ. Of The West Of England Prof Gordon Stamp Imperial College London

RES-340-25-0003 Annex 1.3 Mapping Stem Cell Innovation In Action Dr Clare Williams King's College London, University Of London Prof Alan Cribb King's College London Dr Bobbie Farsides King's College London Mr Nigel Heaton King's College Hospital, London Prof Mike Michael Goldsmiths College, London Mr Steven Wainwright King's College London

RES-340-25-0004 Annex 1.4 Quality Assured Science: The Role Of Standards In Stem Cell Research Prof Andrew Webster University Of York Prof Peter Andrews University Of Sheffield Prof Henry Moore University Of Sheffield Dr Lena Eriksson University Of York

RES-340-25-0007 Annex 1.5 Haematopoietic Stem Cells: The Dynamics Of Expectations In Innovation Dr Paul Martin University Of Nottingham Dr Nik Brown University Of York Dr Alison Kraft University Of Nottingham Prof Philip Bath Univ Nottingham Medical School Professor Joan Fujimura University of Wisconsin Professor Arie Rip University of Twente

RES-340-25-0008 Annex 1.6 The Social Dynamics Of Public Engagement In Stem Cell Research Dr Sarah Parry University Of Edinburgh Dr Sarah Cunningham-Burley University Of Edinburgh Dr Wendy Faulkner University Of Edinburgh Prof Austin Smith University Of Edinburgh Ms Catherine Henderson University Of Edinburgh

6 Annex 1.1

RES-340-25-0001 The Global Politics Of Human Embryonic Stem Cell Regulation Prof Brian Salter University Of East Anglia Dr Catherine Waldby Brunel University Expert Consultancy - Professor Herbert Gottweis University of Vienna Expert Consultancy - Dr Stephen Minger Kings College London

Regulatory policy is a key political site where competition for the social, scientific and industrial future of human embryonic stem cells takes place at the national, regional and international levels. That competition is driven by global political forces which transcend national boundaries as they seek to influence the future shape of regulatory policy. The aim of the project is to develop an analysis of these political forces, to identify their impact on the UK ESC regulatory regime, and explore their implications for UK policy making. Firstly, building on the existing work of the project team, the legislative, organisational and ideological components of the regulatory models currently in use will be mapped in detail and an initial understanding established of the political dynamic at work in this field. Secondly, approximately 100 semi-structured interviews will be used to identify (a) the major pressures for regulatory change from the national and transnational policy networks of civil society, science and industry and (b) further develop the understanding of the political dynamic shaping the likely regulatory response. Finally, the implications for regulatory policy of the analysis thus constructed will be explored with UK policy makers.

7 Annex 1.2

RES-340-25-0002 Forgotten Fetuses - A Sociocultural Analysis Of The Use Of Fetal Stem Cells Dr Julie Kent University Of The West Of England, Bristol Prof Naomi Pfeffer London Metropolitan University Prof Wendy Purcell Univ. Of The West Of England Prof Gordon Stamp Imperial College London

The objective of this research is to contribute to the development of UK policy and practice in relation to fetal stem cells, and to provide some data on which comparisons of the various sources of stem cells may be based. Although UK law and practice around the collection and distribution of aborted fetuses for research are permissive and well- regulated, there are implications for the collection of fetal stem cells, and there is pressure for change. Centred at the MRC [Fetal] Tissue Bank at Hammersmith Hospital, the research will investigate and analyse the social worlds where fetal material is located. In particular, development in regulatory arrangements, especially in relation to tissue banks and tissue engineering, will be observed; and how the use of fetal material as a source of stem cells might affect women's willingness to donate or clinicians' willingness to ask for donations, will be explored.

8 Annex 1.3

RES-340-25-0003 Mapping Stem Cell Innovation In Action Dr Clare Williams King's College London, University Of London Prof Alan Cribb King's College London Dr Bobbie Farsides King's College London Mr Nigel Heaton King's College Hospital, London Prof Mike Michael Goldsmiths College, London Mr Steven Wainwright King's College London

This interdisciplinary collaboration draws together expertise in the sociology of science and technology, medical sociology, medicine/biological science, biomedical ethics and public policy, in a study tracking the development trajectory of innovative stem cell research and clinical treatment. An ethnography of an international centre at the forefront of fetal and adult stem cell research for the treatment of liver disease and diabetes will be contextualised more broadly by interviews with key UK stakeholders. A social science, scientific, medical and ethics literature and policy document analysis will map discourses, debates and shifts in the area of stem cell research. Through early engagement with these important areas in stem cell research and treatment, the study will explore how a new technology might be encouraged or prevented from diffusing from 'bench to bedside', and potentially to market place. It will investigate how discursive and practical procedures and resources are aligned in the process of routinisation of stem cell treatments, and identify how different discourses about stem cells may be mobilised and interpreted by key stakeholders. Theoretically, the study will contribute to sociological literature in the areas of Science and Technology Studies, Time, and the Body. It will also contribute to the development of a more socially embedded account of ethical deliberation and decision making about policies and their effects, as well as to the social and policy contexts of professional and research ethics. This research will produce an insightful social scientific analysis that is commensurate with the pace of contemporary scientific stem cell research. The information gained will be of direct benefit to government and statutory advisory bodies and user groups. It will also contribute to the development of a UK/European legal, regulatory and policy framework, in addition to more general public debate about stem cell research and treatment.

9 Annex 1.4

RES-340-25-0004 Quality Assured Science: The Role Of Standards In Stem Cell Research Prof Andrew Webster University Of York Prof Peter Andrews University Of Sheffield Prof Henry Moore University Of Sheffield Dr Lena Eriksson University Of York

This project examines the socio-technical processes shaping the current development of Embryonic Stem Cells research and innovation, specifically with regard to the establishing of new quality control and safety standards developed and overseen by intermediary institutions. These play a crucial social and scientific role between the science base and end-users, primarily in ensuring the quality of SC lines. This is a key issue on which the future development and stability of the field will depend. Through international and interdisciplinary research including collaboration with other European based social scientists, the project will track the development of standards, their mobilisation across SC socio-technical networks and their stabilisation in the medium term. Five case study sites in the UK and overseas have been identified that play a key intermediary role. This research will have value for policy agencies seeking to operationalise and monitor standards as well as academic and commercial actors entering the field. In addition it will add to the currently limited work in social science on standards and their meaning and mobilisation in contemporary science. This collaborative project brings together researchers in the sociology of science and bioscience to undertake analysis of this process. It adopts a research design where theory building and practice are closely integrated. This is seen as a key ambition of the ESRC's initiative on Stem Cells.

10 Annex 1.5

RES-340-25-0007 Haematopoietic Stem Cells: The Dynamics Of Expectations In Innovation Dr Paul Martin University Of Nottingham Dr Nik Brown University Of York Dr Alison Kraft University Of Nottingham Prof Philip Bath University Nottingham Medical School Professor Joan Fujimura University of Wisconsin Professor Arie Rip University of Twente

The project will focus on haematopoietic stem cells (HSCs) for the treatment of cancer and now other conditions. HSCs reside in the bone marrow and are the immortal progenitors of many tissues in the blood and immune system. Unlike all other stem cell therapies, only a few of which have even been experimentally tested, HSCs have been routinely used as an alternative to bone marrow transplantation since the late 1990s. Novel applications of HSCs are currently being developed for the treatment of other conditions, such as stroke. Their adoption may therefore represent a paradigm for emerging stem cell technologies. Despite the success of HSCs as an important cancer therapy, there has been very little commercial exploitation of this technology. There was an unsuccessful, and now largely forgotten, 'first wave' of industrial interest in HSC technology in the US in the mid 1990s. However, in recent years there has been renewed interest in the commercial potential of the field. The main research question will therefore be: how has haematopoietic stem cell technology been developed as a therapy, to what extent has it been commercially exploited, and what are the prospects for its future development? The project will: 1. Explore how HSC technology has entered the clinic, the creation of research networks, the expectations that shaped clinical development, and the main factors influencing its diffusion; 2. Analyse the industrial development of HSC technology, firm strategies and the expectations that guided them, and the key issues facing attempts to establish commercially viable businesses; 3. Assess the prospects for the future development of HSC technology and identify key barriers to its further diffusion; 4. Recommend public policies to stimulate further clinical development and diffusion, improve the competitiveness of the UK stem cells industry; 5. Examine the utility of using the 'dynamics of expectations' methodology for technology assessment and policy-making.

11 Annex 1.6

RES-340-25-0008 The Social Dynamics Of Public Engagement In Stem Cell Research Dr Sarah Parry University Of Edinburgh Dr Sarah Cunningham-Burley University Of Edinburgh Dr Wendy Faulkner University Of Edinburgh Prof Austin Smith University Of Edinburgh Ms Catherine Henderson University Of Edinburgh

This project aims to (i) to investigate views and concerns of diverse social groups about Stem Cell Research (SCR) and (ii) to explore the scope for increasing public engagement in the developing field. SCR evokes a wide range of social concerns relating both to the development of the technology and its potential application in human medicine. 'Public engagement' seeks to extend the scope and franchise of participation in science, technology and medicine. As a newly emergent technology, SCR is already propelling participants into public debate and raising concerns amongst scientists about the risk of mistrust and hostility. This proposed research will make a practical and analytical contribution to the development and investigation of public engagement techniques, drawing on qualitative research and dialogic techniques, underpinned by conceptual contributions from the sociology of scientific knowledge and public understanding of science. The research team is multi-disciplinary and will act as a mutual learning community through reflexive practice. The research design involves the participation of specialist and non-specialist groups in diverse forms of public engagement, to discuss issues about SCR. We adopt a symmetrical approach to researching scientists and publics, focussing on diversity and convergence. Building on 20 focus groups in the first stage of the study, we will utilise a range of established and experimental forms of public engagement as both topic and resource: 20 follow-up focus groups; 9 dialogic conversations; educational activities and a final public event. Feedback will be through web-based interactions, interviews and questionnaires. Analysis will address themes such as the situated nature of expertise; the construction of social issues in relation to SCR; perceived value of different forms of public engagement; ambivalence in the context of SCR. There will be a wide programme of academic and user dissemination.

12 Annex 2 Genomics Centres

Text to be included…

Page under construction.

Further details to be confirmed

13 Annex 3 International Visiting Fellowships

Up to 10 fellowships, lasting 3 months each, will be available for short visits to recognised UK social science centres to build collaborative links.

Visiting Fellows will be attached to a research centre or project to exchange research results, develop a better understanding of host/visitor research activity in the field, and to establish longer term collaboration beyond the duration of the visit itself.

Further details to follow.

14 Annex 4 Stem Cells and the Media Fellowship

A ‘Stem Cells and the Media’ Fellowship will be offered in the final year to enable an academic working in areas such as media studies, science communication, or public engagement to join the Initiative for a period of up to twelve months, to liaise with those funded by the Initiative and the SCI Co-ordinator and to prepare a specially commissioned report on the field and the findings.

15 Annex 5 Translational Research Fellowships

The recent report by the Health Committee (April 2005) noted that, while there is a history of slow/late adoption of new medical technologies (such as tissue engineering and stem cell therapies) by the NHS, the projected 43% increase in NHS funding between 2003 and 2008 is likely to accelerate this process, but only if there is a more robust and holistic understanding of the problems translating research from the lab to both industry and the clinic. Fellowships would be especially welcomed, therefore, in providing opportunities to explore these problems, especially in regard to:  legal and economic evaluation and review of the field  implementation in clinical settings  business modelling and future options for UK firms (both large and small)  the contrasting socio-economic dynamics of adult and embryonic stem cell research  the role of the media and other information sources in shaping publics’ perceptions of SC and how people decide what information is to be regarded as more valuable and more trusted  the new skills base that will need to be developed (via medical schools, biosciences, bioethics, the social sciences) to meet the needs of SC innovation and implementation

These Fellowships will be encouraged to develop formal links to the UK’s Regional Development Agencies and the centres they have established such as the “Centres of Industrial Collaboration” (e.g., Tissue Engineering and Biomaterials) in Yorkshire and Humberside, ‘BioNow’ in the North West, Health Enterprise East in the Cambridgeshire region, and the Intermediary Technology Institute (ITI Life Sciences) established by Scottish Enterprise.

The fellowships will be awarded with funds direct from the ESRC therefore ESRC application rules will apply.

16 Annex 6 National/International Seminar Series

These events will be run by either the SCI office or The Genomics Forum which will draw on the research strengths of the Genomics Centres to build links to a wider network of social and natural scientists, policy makers and so on. The aim is to raise awareness and profile the role of the ESRC within the wider Stem Cell field.

These workshops/seminars would take different themes, involve the researchers envisaged as being in place in the Centres and elsewhere, draw on the wider resources of SCI, and engage national and international participants, as appropriate. The Genomics Forum workshops will be run early on in Years 2 and 3, while a similar meeting, run by the SCI office will take place at the end of Year 3. The SCI seminar will place particular emphasis on disseminating results of an international nature.

Beyond the seminar series organised by the Forum and SCI, provision will be made for competitive bids to series proposals made from the wider UK social science field, especially those that include participation from clinicians and industry.

Dates and further information will be posted here and on the ‘Events’ page.

17 Annex 7 Public Engagement Events

Further details will be posted here and on the ‘Events’ page.

18 Annex 8 Innovation Cafes

SCI will run a series of ‘Innovation Cafés’, in part based on the Café Scientifique format but in contrast will exclusively focused on SC innovation and translation and more importantly involving presenters from social science, industry and the biosciences, rather than just the social sciences.

19 Annex 9 ESRC Social Science Weeks

20 Annex 10 Interdisciplinary Workshops with Stem Cell Scientists

21 Annex 11 Methodology Workshop

Methodological development in the field will be encouraged through a workshop on methodological innovation in the social science of stem cells focussing on modelling within and between the sciences. This would be hosted by the ESRC National Centre for Research Methods, Manchester which provides support for methodological innovation and excellence in the UK. The workshop will be aimed at post graduate students and research fellows from the social sciences.

22 Annex 12 Genomics Forum 5-Day Training Course

The Genomics Forum proposes to offer a short (5-day) training course in Year 3, for Bioscience postdoctoral students to explore the social sciences and their contribution to the understanding of Stem Cell science and technology. The objective would be to build capacity amongst post doc scientists to appreciate and benefit from engagement with social scientists.

23 Annex 13 Funded Opportunities

Please link each item to the relevant page. Some of this may seem a bit repetitive but it will be useful to have this separate page to direct people more specifically to upcoming funding – other items might yet be added.

The ESRC have so far funded 6 Projects (please link to projects page) and the Genomics Centres (link to Genomics Centres).

Future research and activities are due to be funded. Please visit the link below for further information about when funding will be made available and how to apply.

Research

International Visiting Fellowships From Spring 2006 Stem Cells and the Media Fellowship From Autumn 2007 Translational Research Fellowships From Autumn 2006

Activities

National/International Seminar Series From Spring 2007 Public Engagement Events From Spring 2006 Innovation Cafes From Autumn 2006 ESRC Social Science Weeks From 2007 Interdisciplinary Workshops with Stem Cell Scientists Spring 2007 Methodology Workshop Spring 2007 Genomics Forum 5-Day Training Course Spring 2008