Private Address: Alberto Aguilera 16, 1º Dcha., Madrid 28015-, Spain
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ABBREVIATED C.V. ENRIQUE GOMEZ-BARRENA National ID: 171599113D DOB: April 25th, 1963. Zaragoza, Spain. Citizenship: Spanish Private address: Alberto Aguilera 16, 1º dcha., Madrid –28015-, Spain. Professional address: Dept. Orthopaedic Surgery. Fundación “Jiménez Díaz” Hospital. Avda. Reyes Católicos 2, Madrid –28040-, Spain. Phone: +34.91.5504826 Fax: +34.91.5431071 E-mails: [email protected] ; [email protected];
Degrees and academic background M.D., 1987, Universidad de Zaragoza, Spain Ph.D., 1992, Universidad Autónoma de Madrid, Spain Internship and Residency in Orthopaedic Surgery, 1987-92, Hospital “La Paz”, Madrid, Spain Orthopaedic Research Fellowship, 1994, Hospital for Special Surgery, New York, NY
Other certificates E.C.F.M.G. (Educational Comission for Foreign Medical Graduates, Philadelphia, Pennsylvania, U.S.A.) Certification, january 1994. T.O.E.F.L. (Test of English as a Foreign Language), april 1993.
Hospital appointments Staff Orthopaedic Surgeon, Hospital “La Paz”, Madrid, Spain, 1993, 1995-1996 Staff Orthopaedic Surgeon, Hospital “Ntra. Sra. De Gracia”, Zaragoza, Spain, 1996-2000. Staff Orthopaedic Surgeon, Fundación “Jiménez Díaz” Hospital, Madrid, Spain, since 2000. Associated Chief, Orthopaedic Surgery, Fundación “Jiménez Díaz” Hospital, Madrid, Spain, since 2007.
Academic Appointments Assistant Professor, Universidad Autónoma de Madrid, 1996 Permanent Professor of Orthopaedic Surgery, Universidad Autónoma de Madrid, since 2000. Chair, Orthopaedic Surgery, Universidad Autónoma de Madrid, since 2007. Vice-Dean, Universidad Autónoma de Madrid Medical School, since 2004
Research Involved in 13 research grants (Spanish National Agencies), Management Committee of 537-EU COST action (European Science Foundation), Member and Steering Board of REMEDIC EU network (ESF). Main interest in total joint replacement and biomaterials (polyethylene) and knee reconstruction (proprioception). Selected papers: - Salvati EA, Gómez Barrena E: "The contribution of metallic debris to osteolysis." Orthopaedics 1994; 17/9: 763-765. - Salvati EA, Gómez Barrena E: "Outcomes of cemented total hip replacement of the first generation" en NIH Consensus Development Conference on Total Hip Replacement. NIH, Bethesda MD, U.S.A. 1994, pp 105- 110. - Ballesteros R, Chacon M, Cimarra A, Ramos L, Gómez-Barrena E: "Traumatic dislocation of the tibialis posterior tendon: A new surgical procedure to obtain a strong reconstruction." J. Trauma 1995; 39/6: 1198- 1200. - Li S, Chang JD, Barrena EG, Furman BS, Wright TM, Salvati EA: "Non-consolidated polyethylene particle defects in Charnley acetabular cups." Clin Orthop Rel Res 1995; 319: 54-63. - Gómez Barrena E, Chang JD, Li S, Rimnac C, Salvati EA: "The role of polyethylene properties in osteolysis after total hip replacement." In Pritchard DJ (ed.): 'Instructional Course Lecture 45', Ed. AAOS, Park Ridge IL, U.S.A., 1996, pp 187-197. - Xu J-W, Konttinen YT, Waris V, Gómez-Barrena E, Sorsa T, Santavirta S. “Granulocyte-macrophage colony stimulating factor (GM-CSF) in the aseptic loosening of total hip arthroplasty.” J Orthop Rheumatol 1996; 9: 128-134. - Gomez-Barrena E, Martinez-Moreno E, Munuera L: “Segmental sensory innervation of the anterior cruciate ligament and the patellar tendon of the knee.” Acta Orthop Scand. 1996; 67 (6): 545-552. - Gomez-Barrena E, Nuñez A, Martinez-Moreno E, Valls J, Munuera L: “Neural and muscular electric activity in the cat’s knee. Changes when the anterior cruciate ligament is transected.” Acta Orthop Scand. 1997; 68 (2):149-155. - Santavirta S, Konttinen YT, Lappalainen R, Anttila A, Goodman SB, Lind M, Smith L, Takagi M, Gómez- Barrena E, Nordsletten L, Xu JW: “Materials in Total Joint Replacement.” Curr Orthop 1998; 12: 51-57. - Gómez-Barrena E, Li S, Furman BS, Masri BA, Wright TM, Salvati EA: "Role of polyethylene oxidation and consolidation defects in the performance of Charnley acetabular cups." Clin. Orthop. Rel. Res. 1998, 352: 105-117. - Gomez-Barrena E, Martinez-Moreno E, Ballesteros R, Martinez D, Munuera L: “Gold chloride technique to study articular innervation. A protocol validated through computer-assisted colorimetry.” Histol. Histopathol. 1999; 14: 69-79. - Santavirta S, Takagi M, Gómez-Barrena E, Lassus J, Salo J, Konttinen Y. “Studies on host response to orthopaedic implants and biomaterials.” Journal of Long-Term Effects of Medical Implants 1999; 9: 1-10. - Gómez-Barrena E, Nuñez A, Ballesteros R, Martínez-Moreno E, Munuera L. “Anterior cruciate ligament reconstruction affects proprioception in the cat’s knee.” Acta Orthop Scand 1999; 70: 185-193. - Puértolas JA, Larrea A, Gómez-Barrena E: “Fracture behavior of UHMWPE in non implanted, shelf aged knee prostheses after gamma irradiation in air”. Biomaterials 2001; 22: 2107-2114. - Konttinen YT, Xu JW, Waris E, Li TF, Gómez-Barrena E, Nordsletten L, Santavirta S. Interleukin-6 in aseptic loosening of total hip replacement prostheses. Clin Exp Rheumatol 2002; 20: 485-490. - De Lucas-Villarrubia JC, Lopez-Franco M, Granizo JJ, De Lucas-Garcia JC, Gomez-Barrena E. Strategy to control methicillin-resistant Staphylococcus aureus post-operative infection in orthopaedic surgery. Int Orthop. (SICOT) 2004, 28:16–20 - Medel F, Gómez-Barrena E, García-Alvarez F, Ríos R, Gracia-Villa L, Puértolas JA: Fractography evolution in UHMWPE accelerated aging after gamma irradiation in air. Biomaterials 2004, 25: 9-21. - Gómez-Barrena E, Sánchez O, Largo R, Calvo E, Esbrit P, Herrero-Beaumont G: Changes in articular cartilage immunostaining for parathyroid hormone-related protein (PTHrP) in two progressive experimental models of antigen-induced arthritis and post-meniscectomy osteoarthritis. Ann Rheum Dis. 2004 Aug;63(8):917-22. - Urriés I, Medel FJ, Ríos R, Gómez-Barrena E, Puértolas JA: Comparative fatigue resistance study of electron beam and gamma irradiated UHMWPE. J Biomed Mater Res. 2004 Jul 15;70B(1):152-60. - Medel FJ, García-Alvarez F, Gómez-Barrena E, Puértolas JA: Microstructure changes of extruded ultra high molecular weight polyethylene after gamma irradiation and shelf-aging. Polym Degrad Stab 2005; 88: 435- 43 - Puértolas JA, Medel FJ, Cegoñino J, Gomez-Barrena E, Ríos R: Influence of the remelting process on the fatigue behavior of electron beam irradiated UHMWPE. J Biomed Mater Res B Appl Biomater. 2006 Feb;76(2):346-53. - Konttinen Y, Wright TM, Trebse R, Takagi M, Silbermann M, Salo J, Rieker C, Pioletti DP, Ogino T, Nordsletten L, Lappalainen R, Jiranke W, Goodman SB, Gomez-Barrena E, Draenert KD, Aspenberg P: Total joint replacement and aseptic loosening. Helix Review Series Rheumatology 2006, 8 (1): 98-102. - Konttinen YT, Tiainen V-M, Gomez-Barrena E, Hukkanen M, Salo J. Innervation of the joint and role of neuropeptides. Ann. N.Y. Acad. Sci.2006, 1069: 149–154. - Gómez-Barrena E, Lindroos L, Čeponis A, López-Franco M, Sanchez-Pernaute O, Mönkkönen J, Herrero- Beaumont G, Konttinen YT. Cartilage oligomeric matrix protein (COMP) is modified by intra-articular liposomal clodronate in an experimental model of arthritis. Clin Exp Rheumatol. 2006 Nov-Dec;24(6):622- 628. - Bonsfills N, Raygoza JJ, Boemo E, Garrido J Nuñez A, Gómez-Barrena E: Time-dependent strain variations are detected in soft-tissues around unstable knees after anterior cruciate ligament injury. An in vivo experimental study on the cat’s knee. The Knee. 2007 Jan;14(1):39-45. - Medel FJ, Peña P, Cegoñino J, Gómez-Barrena E, Puértolas JA. Comparative fatigue behavior and toughness of remelted and annealed highly crosslinked polyethylenes. J Biomed Mater Res B Appl Biomater 2007; 83(2): 380-90. - Lacoste F, Granizo JJ, Gómez-Barrena E: Reliability of a simple fluoroscopic method to study sagittal plane femorotibial contact changes during total knee arthroplasty flexion. The Knee 2007; 14: 289-294. - Gómez-Barrena E, Bonsfills N, Martin G, Ballesteros-Massó R, Foruria A, Nuñez-Molina A: Insufficient recovery of neuromuscular activity around the knee after experimental anterior cruciate ligament reconstruction. Acta Orthop 2008 Feb;79(1):39-47. - Esteban J, Gomez-Barrena E, Cordero J, Zamora N, Kinnari TJ, Fernandez-Roblas R. Evaluation of semiquantitative cultures from sonicated retrieved orthopaedic implants in the diagnosis of orthopaedic infection. J Clin Microbiol. 2008 Feb;46(2):488-92. - Kinnari T, Soininen A, Esteban J, Zamora N, Alakoski E, Kouri VP, Anttila A, Lappalainen R, Konttinen YT, Gomez-Barrena E, Tiainen VM. Adhesion of Staphylococcal and caco-2 cells on diamond-like carbon polymer hybrid coating. J Biomed Mater Res A. 2008 Sep;86(3):760-8. - Virtanen S, Milošev I, Gomez-Barrena E, Trebše R, Salo J, Konttinen YT. Special modes of corrosion under physiological and simulated physiological conditions. Acta Biomater. 2008 May;4(3):468-76. - Garcia-Alvarez F, Castiella T, Guallar E, Grasa JM, Gomez-Barrena E, Lacleriga A. Influence of platelet time activation on articular cartilage growth in the rabbit knee. Preliminary study. The Knee. 2008 Aug;15(4):314-7. - Bonsfills N, Gomez-Barrena E, Nuñez A. Loss of neuromuscular control related to motion in the acutely ACL-injured knee. An experimental study. Eur J Appl Physiol 2008 Oct;104(3):567-77. - Gomez-Barrena E, Puertolas JÁ, Munuera L, Konttinen YT. UHMWPE research update: From the bench to the bedside. Acta Orthop 2008 Dec;79(6):832-40. - Kinnari TJ, Esteban J, Martin-de-Hijas NZ, Sánchez-Muñoz O, Sánchez-Salcedo S, Colilla M, Vallet-Regí M, Gomez-Barrena E. The influence of surface porosity and pH on bacterial adherence to hydroxyapatite and biphasic calcium phosphate bioceramics. J Med Microbiol. 2009 Jan;58(Pt 1):132-7. - Kinnari TJ, Esteban J, Gomez-Barrena E, Zamora N, Fernandez-Roblas R, Nieto A, Doadrio JC, López- Noriega A, Ruiz-Hernández E, Arcos D, Vallet-Regí M. Bacterial Adherence to SiO2 based multifunctional bioceramics. En prensa J Biomed Mater Res A. 2008 Apr 22. [Epub ahead of print] - Goodman SB, Konttinen YT, Takagi M, Gomez-Barrena E. Biocompatibility of joint replacements. En prensa J Biomed Mater Res A. 2008 May 28. [Epub ahead of print] - Bonsfills N, Nuñez A, Gomez-Barrena E. Muscle stimulation controls anterior knee laxity after experimental ACL section. En prensa, Arch Orthop Trauma Surg. 2008 Sep 27. [Epub ahead of print] - Pascau A, Guardia B, Puértolas JA, Gómez-Barrena E: A knee model of hydrodynamic lubrication during the gait cycle and the influence of prosthetic joint conformity. In press. J Orthop Sci (24-9-08). - Lozano D, F de Castro L, Dapia S, Andrade-Zapata I, Manzarbeitia F, Alvarez-Arroyo MV, Gomez-Barrena E, Esbrit P. Role of Parathyroid Hormone-Related Protein in the decreased osteoblast function in diabetes- related osteopenia. In press, Endocrinology (27-1-09). - Martín-de-Hijas N, García-Almeida D, Ayala G, Fernandez-Roblas R, Gadea I, Gómez-Barrena E, Esteban J. Biofilm development by clinical strains of non-pigmented rapidly growing mycobacteria. In press,, Clin Mic Infect (13-03-09). Membership Member, Spanish Society of Orthopaedic Surgery and Traumatology (SECOT), since 1992 (Associate Member, 1988-92). Member, European Orthopaedic Research Society (EORS), since 1991. Member, Spanish Society of the Knee (SEROD) since 1992. International Member, American Academy of Orthopaedic Surgeons (AAOS), since 1997. Member, Iberian Society of Biomechanics and Biomaterials, since 2000. Member, Orthopaedic Research Society (ORS), since 2000. Vice-President, European Orthopaedic Research Society (EORS), since 2008.
Participation in meetings and publications 34 publications in books 77 published papers 130 presentations in National and International Meetings Referee: Revista de Ortopedia y Traumatología. Acta Orthopaedica Scandinavica. Journal of Bone and Joint Surgery [Br] Journal of Biomedical Materials Research B Applied Biomaterials Chemical Engineering Journal Clinical Orthopaedics and Related Research Clinical Anatomy Diamond and related materials Journal of Cellular and Molecular Medicine Journal of Orthopaedic Research Journal of Rheumatology Libertas Academica Seminars in Arthritis and Rheumatism The Knee The Open Orthopaedic Journal Editorial Board Techniques in Knee Surgery, Lippincott Williams and Wilkins, Hagerstown MD, USA, since 2002. Algia Hospital, Ergon, Madrid, since 2006 (Co-editor) The Open Orthopaedic Journal, Bentham, UK, since 2007. Chirurgia degli Organi di Movimento-Musculoskeletal Surgery, Springer, since 2009. Scientific Committee, XXI Congress of SEROD, Madrid (Spain), 2002. Scientific Committee, 13rd Annual Meeting EORS, Helsinki (Finland), 2003. Scientific Committee, 41 Congress of SECOT, Madrid (Spain), 2004. Scientific Committee, 16th Annual Meeting EORS, Bologna (Italy), 2006. Chair, Organizing Committee, 3rd UHMWPE International Meeting, Madrid (Spain), 2007. Chair, Organizing Committee, 17th Annual Meeting EORS, Madrid (Spain), 2008.