WHITE NIGHTS St. Petersburg International Oncology Forum

JUNE, 20-23, 2019 WWW.FORUM-ONCO.RU

PROGRAMME SAINT-PETERSBURG | WWW.FORUM-ONCO.RU | FORUM`S SESSIONS SCHEDULE | JUNE, 20, THURSDAY

зал места 08.00 08.30 09.00 09.30 10.00 10.30 11.00 11.30 12.00 12.30 13.00 13.30 14.00 14.30 15.00 15.30 16.00 16.30 17.00 17.30 18.00 18.30 19.00 19.30 20.00

Lung cancer: multidisciplinary approach Sponsored Lung cancer: multidisciplinary approach Sponsored symposium Blue 1 180 symposium

The Fifth M.L.Gershanovich Conference «Treatment The Fifth M.L.Gershanovich Conference Blue 2 250 «Treatment individualization: from science Sponsored symposium individualization: from science to practice» with interactive to practice» with interactive voting: Key issues voting: Key issues

Blue 3 180 New strategies in gynecology: live surgery 3D, presentations, Discussion

Blue 4 330 Current capabilities of breast cancer reconstructive surgery Break Current capabilities of breast cancer reconstructive surgery

Blue 5 250 Workshop session «Live surgery»: pancreas cancer

Green 5 50 Biology of informal financial relations in oncology Break SPOT: lifehacks for young oncologists

Green Multidisciplinary approach in oncogynecological diseases Multidisciplinary approach in oncogynecological diseases 100 Break 6+7 radiology radiology

Cancer service development perspectives Sponsored symposium Analysis of the KSG Cutaneous melanoma: new approaches to treatment within the framework of Green 8 120 system. Subtotals the «Healthcare» national project

Green 9 170 Workshop session “Live surgery»: head and neck tumors

Green New challenges for fight against cancer Break New challenges for fight against cancer 10 70

Red 8+9 100 Molecular oncourology Sponsored symposium Molecular oncourology

Red 10 120 Outpatient oncology Sponsored symposium Outpatient oncology

Red 11 170 Diagnostic and treatment process safety: contribution of a nurse Break Diagnostic and treatment process safety: contribution of a nurse

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SAINT-PETERSBURG | WWW.FORUM-ONCO.RU | FORUM`S SESSIONS SCHEDULE | JUNE, 21, FRIDAY

зал места 08.00 08.30 09.00 09.30 10.00 10.30 11.00 11.30 12.00 12.30 13.00 13.30 14.00 14.30 15.00 15.30 16.00 16.30 17.00 17.30 18.00 18.30 19.00 19.30 20.00

Workshop Workshop session «Live surgery»: session «Live Blue 1 180 lung cancer surgery»: lung cancer

Blue 2 250 Pancreatic tumours Sponsored symposium Pancreatic tumours

Joint session: ESGO (European Society Joint session: ESGO (European Society of of Gynecological Oncology) - RSGO Break Gynecological Oncology) - RSGO (Russian Blue 3 180 (Russian Society of Gynecological Society of Gynecological Oncology) Oncology)

Blue RAOM session (Russian Association of The Fifth M. L.Gershanovich Conference «Breast cancer - Personalized Cancer 600 Sponsored symposium Sponsored symposium 4+5 Oncological Mammology) Therapy: from science to practice» with interactive voting

Green 5 50 Cardio-oncology MELANOMA.PRO domestic research Cardio-oncology

Green Cancer care in the Russian Federation Break Organizational and legal aspects of cancer care in the Russian Federation 6+7 100

Green 8 120 Smoking and cancer Sponsored symposium Roundtable discussion with the participation of mass media

Green 9 170 «Live surgery» workshop session: endoscopy «Live surgery» workshop session: endoscopy

Green Neuroblastoma in children: current issues of diagnosis and Neuroblastoma in children: current issues of diagnosis and 70 Break 10 management management

«Live surgery 3D» workshop «Live surgery» workshop session: endoscopy Red 8 70 session: oncourology

Clinical research - science, international experience and investment in the medicine of Clinical research - science, international experience and investment in the medicine of future. Sponsored symposium Red 9 70 future. Section in the memory of Mikhail Lichinitser Section in the memory of Mikhail Lichinitser

Red 10 120 Tumors of bones and soft tissues Sponsored symposium Tumors of bones and soft tissues

The Fifth M. L. Gershanovich Conference «Head and RUSSCO session Neck tumours- Personalized Cancer Therapy: from Sponsored symposium Red 11 170 Molecular imaging in oncology science to practice» with interactive voting Official opening of the V St. Petersburg International Oncological Forum «White Nights 2019»- Blue 4+5 2019»- Forum «White Nights Oncological International Petersburg V St. the of Official opening

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зал места 08.00 08.30 09.00 09.30 10.00 10.30 11.00 11.30 12.00 12.30 13.00 13.30 14.00 14.30 15.00 15.30 16.00 16.30 17.00 17.30 18.00 18.30 19.00 19.30 20.00

Sponsored Panel meeting of the Ministry of Healthcare symposium Blue 1 180 Palliative Care of the Russian Federation specializing in palliative medical care

Circulating nano-vesicles: their role in oncological diseases pathogenesis and prospects for Break Current issues of anesthesiology and intensive care Blue 2 250 application in oncology practice

Discussion in cervical cancer treatment Prevention and risk management in an Blue 3 180 State-of-the-art Sponsored symposium oncology clinic. How to protect yourself Clinical case studies and a clinic

Meeting of the European Society of Surgical Oncology Debatable issues of colorectal cancer Break Blue 4 330 (ESSO) during the White Nights Forum 2019

Sponsored symposium Blue 5 250 Fundamental aspects of cancer immunology Fundamental aspects of cancer immunology

Green 5 50 Organization of medical care for children with oncological diseases Break Organization of medical care for children with oncological diseases

Green Roundtable discussion. Multidisciplinary discussion of microbiome role in oncology 100 Break Conference «Automated Information Systems in Medicine 2019» 6+7 «Microcosm in a body’s macrocosmos»

Applied bioethics in medical Training course on radical prostatectomy Break Green 8 120 communication and journalism

Green 9 170 Head and neck tumors Перерыв Sponsored symposium Head and neck tumors

Green Managing cancer care Break Session of young cancer psychology scientists 10 70

Red 8+9 100 Neuroradiology Break Radiation therapy of malignant tumours of various localizations

Red 10 120 Current immunotherapy. What has changed? Sponsored symposium Germ cell tumors in men

Sponsored symposium Session of European School of Oncology: Current The Fifth M. L. Gershanovich Conference «GI tumours treatment Red 11 170 issues of gastrointestinal tumors treatment individualization: from science to practice» with interactive voting

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SAINT-PETERSBURG | WWW.FORUM-ONCO.RU | FORUM`S SESSIONS SCHEDULE | JUNE, 23, SUNDAY

зал места 08.00 08.30 09.00 09.30 10.00 10.30 11.00 11.30 12.00 12.30 13.00 13.30 14.00 14.30 15.00 15.30 16.00 16.30 17.00 17.30 18.00 18.30 19.00 19.30 20.00

Blue 1 180 Symposium «Evolutionary oncology and evolutionary virology» Break Symposium «Evolutionary oncology and evolutionary virology»

Blue 2 250 A school for young oncourology doctors: Prostate cancer diagnosis

Blue 3 180

Blue 4 330 Geriatrics in oncology: diagnosis, treatment, and accompanying therapy Break Geriatrics in oncology: diagnosis, treatment, and accompanying therapy

Blue 5 250 Actual issues of cancer patients rehabilitation Break Actual issues of cancer patients rehabilitation

Role of medical insurance organizations in Business etiquette Green 5 50 protection of the cancer patients rights

Green Current issues of morphological diagnosis in oncology 100 Current issues of morphological diagnosis in oncology practice Break 6+7 practice

Green 8 120 Nuclear medicine in malignant tumors diagnosis and treatment Break Nuclear medicine in malignant tumors diagnosis and treatment

Scientific practical conference of the Problem Commission «Head and neck Scientific practical conference of the Problem Commission «Head and neck tumors» of the tumors» of the Scientific Council on malignant neoplasms of the Russian Scientific Council on malignant neoplasms of the Russian Academy of Sciences and the Academy of Sciences and the Ministry of Health of Russia «Modern methods of Break Green 9 170 Ministry of Health of Russia «Modern methods of diagnosis and treatment of recurrences and diagnosis and treatment of recurrences and distant head and neck malignant distant head and neck malignant neoplasms metastases» neoplasms metastases»

Green Cryosurgery in cancer treatment Break Cryosurgery in cancer treatment 10 70

Perspectives of geroprotectors Red 8 70 Perspectives of geroprotectors as anti-cancer agents Break as anti-cancer agents

Conference on Fundamental Oncology «Petrovskie Conference on Fundamental Oncology «Petrovskie Red 9 70 chtenia» (School of Young Scientists) Supported by the Break chtenia» (School of Young Scientists) Supported by the RSF (Grant №17–75–30027) RSF (Grant №17–75–30027)

Why do patients resort to pseudoscientific cancer Red 10 120 Pharmacoeconomics in oncology Break treatments? Opinion based on scientific communication, sociology and neuropsychology

Red 11 170 Session with European Organization for Trophoblastic Disease (EOTTD)

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Hall Blue 1

JUNE, 20, THURSDAY

09.00–17.00 Issues of surgical and combined lung cancer treatment

09.00–12.00 Session 1. Optimization of early non-small cell lung cancer treatment

Chairs: Vladimir Porkhanov, Scientific Research Institute – Ochapovsky Regional Clinical Hospital № 1, Krasnodar Raja Flores, Mount Sinai Hospital, New York, USA Yukihiro Yoshida, National Cancer Center, Tokyo, Japan 09.00–09.30 Therapeutic strategy for small sized lung cancer in Japan Yukihiro Yoshida, National Cancer Center, Tokyo, Japan 09.30–09.45 Stage I lung cancer - why I will perform a conventional thoracoscopic lobectomy Pavel Kononets, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, 09.45–10.00 Stage I lung cancer - why I will perform a RATS lobectomy Petr Yablonsky, «FSBI «St.Petersburg Research Institute of phthisiopulmonology» of the Ministry of Health of the Russian Federation, St. Petersburg 10.00–10.15 Why I will perform bronchoplastic lobectomy Vitaly Danilov, Scientific Research Institute – Ochapovsky Regional Clinical Hospital № 1, Krasnodar 10.15–10.45 Open versus VATS & RATS lobectomy for early stage lung cancer Raja Flores, Mount Sinai Hospital, New York, USA 10.45–11.00 Open broncho(angio)plastic interventions in case of lung cancer Nikita Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.00–11.15 Stereotactic radiation therapy options for lung cancer Sergey Novikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.15–11.30 The results of the accelerated recovery protocol application in lung tumors surgery Aleksander Kachur, Clinical hospital №1 «Medsi», Moscow 11.30–12.00 Discussion

12.00–12.30 Break

12.30–14.00 Sponsor symposium lunch** ** (Not included in the CME program)

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Hall Blue 1

14.00–17.10 Session 2. Combination therapy of operable locally advanced lung cancer

Chairs: Ivan Stilidi, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Evgeny Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.00–14.15 Role of a pathologist in determining treatment tactics for operable NSCLC Alexander Ivantsov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.15–14.30 Neoadjuvant and adjuvant therapy advantages in operable NSCLC treatment Dinara Sakaeva, Republican сlinical oncology center, Ufa 14.30–14.45 Is chemoradiotherapy of locally advanced lung cancer an alternative to surgical treatment? Natalia Dengina, State healthcare clinical oncology center, Ulyanovsk 14.45–15.00 Angioplastic surgical interventions in lung cancer surgery Dmitry Chichevatov, FSBEI for Additional Professional Education of Russian Medical Academy Continuous Professional Education of the Ministry of Health of the Russian Federation, Penza 15.00–15.15 Combined resections in the surgical management of locally advanced lung cancer Stepan Ergnyan, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.15–15.30 Is there a place for post-surgery radiation treatment in patients with NSCLC? Oleg Pikin, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 15.30–15.45 Local hyperthermia in combined treatment of locally advanced lung cancer Aleksander Zavyalov, Scientific and Practical Center for Clinical Research and Medical Technology Assessment of the Moscow City Healthcare Department, Moscow 15.45–16.00 Role of molecular diagnostics in operable lung cancer treatment Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.00–16.15 Place of immunotherapy in treatment of operable patients with NSCLC Sergey Orlov, Pavlov First St.Petersburg State Medical University, St. Petersburg 16.15–16.30 Role of target therapy in treatment of operable patients with NSCLC Daniil Stroyakovskiy, Moscow city oncology hospital № 62, Moscow 16.30–16.50 Transfer of lung cancer in operable condition, the urgent task of medical treatment Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.50–17.10 Discussion 18.30–20.00 Sponsor symposium lunch** ** (Not included in the CME program)

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Hall Blue 2

10.00–17.35 The Fifth M.L.Gershanovich Conference «Treatment individualization: from science to practice» with interactive voting: Key issues

10.00–12.30 Session 1 Expert panel: Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Avgust Garin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Nicholas Pavlidis, Ioannina University, Ioannina, Greece Nikolay Zhukov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow Inna Zheleznyakova, FSBI «Center for Healthcare Quality Assessment and Control» of the Ministry of Healthcare of the Russian Federation, Moscow Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Evgeny Imyanitov. FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.00–10.25 From empirical search for anticancer medicinal products to creation of targeted drugs Avgust Garin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.25–10.30 Discussion 10.30–10.55 Diagnosis-related group (DRG) - a new model of financing medical care in the CHI channel Inna Zheleznyakova, FSBI «Center for Healthcare Quality Assessment and Control» of the Ministry of Healthcare of the Russian Federation, Moscow 10.55–11.00 Discussion 11.00–11.25 Theoretical and biological aspects of neoadjuvant therapy Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.25–11.30 Discussion 11.30–11.55 Adjuvant and neoadjuvant therapy. All you wanted to know but hesitated to ask... 5 years later Nikolay Zhukov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology , Moscow 11.55–12.00 Discussion 12.00–12.30 Cancer of Unknown Primary: Diagnostic and Therapeutic Dilemmas Nicholas Pavlidis, Ioannina University, Ioannina, Greece 12.30–14.00 Sponsor symposium lunch** ** (Not included in the CME program)

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Hall Blue 2

14.00–15.35 Session 2 Expert panel: Avgust Garin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Aleksey Novik, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Boris Afanasyev, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St. Petersburg Sergey Alekseev, SBHI «Leningrad regional clinical oncology center», St. Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.00–14.25 Immunotherapy in lymphomas treatment Boris Afanasyev, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St. Petersburg 14.25–14.30 Discussion 14.30–15.00 Gene therapy and cell therapy Sergey Alekseev, SBHI «Leningrad regional clinical oncology center», St. Petersburg 15.00–15.05 Discussion 15.05–15.30 Specific responses to immunotherapy: pseudoprogression and hyperprogression Aleksey Novik , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.30–15.35 Discussion 15.35–17.35 Session 3 Expert panel: Avgust Garin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Dilyara Kaydarova, Kazakh Oncology and Radiology Research Institute of the Ministry of Healthcare of the Republic of Kazakhstan, Almaty, Kazakhstan Diana Nevzorova , SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow 15.35–16.00 Definition dictionary for a clinical oncologist Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.00–16.05 Discussion

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Hall Blue 2

16.05–16.30 Path to precision therapy of malignant tumors Dilyara Kaydarova, Kazakh Oncology and Radiology Research Institute of the Ministry of Healthcare of the Republic of Kazakhstan, Almaty, Kazakhstan 16.30–16.35 Discussion 16.35–17.00 Generics and biosimilars Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.00–17.05 Discussion 17.05–17.30 Palliative medical care for cancer patients Diana Nevzorova, SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow 17.30–17.35 Discussion

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Hall Blue 3

09.00–16.00 New strategies in gynecology: live surgery, presentations, Discussion

09.00–14.30 «Live surgery» workshop session: cervical cancer Moderators: Todua Irakli, «Innova» medical center, Tbilisi, Georgia Artem Stepanyan, «Nairi» medical center, Armenia, Yerevan 09.00–12.00 Live surgery. 3D laparascopy. Radical hysterectomy Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.00–12.30 Break 12.30–14.30 Pelvic evisceration in locally advanced cervical cancer Igor Berlev, Kirill Shostka, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.30–16.00 New strategies in gynecologic oncology Chairs: Todua Irakli, «Innova» medical center, Tbilisi, Georgia Artem Stepanyan, «Nairi» medical center, Armenia, Yerevan Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Konstantin Puchkov, SwissClinic, Moscow 14.30–14.45 Capabilities of vaginal access in cervical cancer surgery Todua Irakli, «Innova» medical center, Tbilisi, Georgia 14.45–14.50 Discussion 14.50–15.10 Video presentation: The Laparoscopic Laterally Extended Endopelvic Resection Artem Stepanyan, «Nairi» medical center, Armenia, Yerevan 15.10–15.15 Discussion 15.15–15.30 Role of laparoscopy in gynecology Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.30–15.35 Discussion 15.35–16.00 Conclusion

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Hall Blue 4

08.00–09.30 Current capabilities of breast cancer reconstructive surgery

Chairs: Mark W. Clemens, The University of Texas MD Anderson Cancer Center, Houston, USA Vladimir Sobolevsky, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Petr Krivorotko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.00–08.20 Breast reconstruction. Where are we now? Arthur Ismagilov, «KSMA - branch of FSBEI for Additional Professional Education of Russian Medical Academy Continuous Professional Education of the Ministry of Health of the Russian Federation», Kazan, the Republic of Tatarstan 08.20–08.35 Breast reconstruction planning in combination with CT vascular mapping Konstantin Zernov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.35–08.55 Complications of DIEP breast reconstruction Vladimir Sobolevsky, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.55–09.15 Achieving High Reliability DIEP Flap Breast Reconstruction Mark W. Clemens, The University of Texas MD Anderson Cancer Center, Houston, USA 09.15–09.30 Discussion

09.30–11.25 Joint session - Central-Eastern European Breast Cancer Surgical Consortium. Evolution of breast-conserving surgery

Chairs: Zoltan Matrai, National Institute of Oncology, Budapest, Hungary Baughman Beth, Sedona Breast Care Clinic, Sedona, USA Alexander Bessonov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.30–09.50 Evaluation of the retroglandular oncoplastic technique as a standard Level I oncoplastic breast-conserving surgery. A retrospective clinico- pathological study of 102 breast cancer patients Zoltan Matrai, National Institute of Oncology, Budapest, Hungary 09.50–10.10 Breast-conserving surgery. Standard and outside-of-the-box solutions Azizzhon Zikiryakhodzhayev, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 10.10–10.30 Oncoplastic BCS as surgery of choice. Subjective and objective results evaluation Alexander Bessonov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.30–10.50 Tumor marking and intraoperative localization in breast-conserving surgery Baughman Beth, Sedona Breast Care Clinic, Sedona, USA

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Hall Blue 4

10.50–11.10 Biological and synthetic meshes in implant-based breast reconstruction - more possibilities for our patients in oncology Dawid Murawa, Poland Baptism Monument Hospital, Gniezno, Poland 11.10–11.25 Discussion

11.25–13.00 Partial breast cancer radiation therapy for surgeons

Chairs: Sergey Novikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Jose Luis Guinot , Jefe Clínico de la Unidad de Braquiterapia, Madrid, Spain Alexander Petrovsky, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 11.25–11.45 New trends in multicatheter interstitial breast brachytherapy (MIBT) for accelerated partial breast irradiation (APBI) Jose Luis Guinot, Jefe Clínico de la Unidad de Braquiterapia, Madrid, Spain 11.45–12.05 External beam radiotherapy Oksana Trofimova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.05–12.25 Intraoperative radiation therapy Alexey Manikhas, St. Petersburg City clinical oncology center, St. Petersburg 12.25–12.45 A surgeon’s vision of partial radiation therapy Alexander Petrovsky, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.45–13.00 Discussion 13.00–14.30 Break

14.30–16.05 Neoadjuvant systemic treatment of patients with breast cancer

Chairs: Mona Frolova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation», Moscow Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Petr Krivorotko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.30–14.50 Neoadjuvant systemic treatment of breast cancer - modern view Mona Frolova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.50–15.10 Luminal breast cancer Vladislav Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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Hall Blue 4

15.10–15.30 Triple negative breast cancer Elena Kovalenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.30–15.50 HER2-positive breast cancer Petr Krivorotko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.50–16.05 Discussion

16.05–18.00 Breast cancer surgery following neoadjuvant chemotherapy

Chairs: Elena Slonimskaya, Tomsk National Research Medical Center, Tomsk Vahit Ozmen, İstanbul Üniversites, İstanbul, Turkey Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.05–16.25 Features of surgical management after breast cancer neoadjuvant treatment Vahit Ozmen, İstanbul Üniversitesi İstanbul Tıp Fakültesi Genel Cerrahi A.D, İstanbul, Turkey 16.25–16.45 Surgical staging of axillary region after neoadjuvant chemotherapy Alexander Emelyanov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.45–17.05 Debatable issues of treatment planning for residual breast cancer after neoadjuvant chemotherapy Sergey Ereshchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 17.05–17.25 Optimization of breast cancer surgical management based on tumor genetic landscape Polina Kazantseva, Tomsk National Research Medical Center, Tomsk 17.25–17.45 Training programs and accreditation for oncology centers Ruben Orda, Tel-Aviv University, Tel-Aviv, Israel 17.45–18.00 Discussion

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Hall Blue 5

09.00–17.00 Workshop session «Live surgery»: pancreas cancer

Moderators: Sergey Bagnenko, Pavlov First St.Petersburg State Medical University, St. Petersburg Bogdan Kotiv, S.M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation, St. Petersburg Alexey Karachun, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Martin Kreis, Charité – Universitätsmedizin Berlin, Berlin, Germany 09.00–13.00 Laparoscopic pancreaticoduodenectomy (A.S. Loginov Moscow clinical scientific center) Surgeon: Igor Hatkov 13.00–13.30 Break 13.30–16.30 Open pancreaticoduodenectomy (FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation) Surgeon: Vladimir Zagainov 16.30–17.00 Discussion

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Hall Green 5

08.00–11.30 Biology of informal financial relations in oncology

Chairs: Vadim Gushchin, Mercy Medical Center, Baltimore, USA Taryn Vian, University of San Francisco, San Francisco, USA 08.00–08.10 Session start. Opening 08.10–08.30 The impact of unofficial payments and decision making in oncology Vadim Gushchin, Mercy Medical Center, Baltimore, USA 08.30–08.50 Discussion 08.50–09.10 The unspoken barrier to quality: corruption in the health sector Taryn Vian, University of San Francisco, San Francisco, USA 09.10–09.30 Discussion 09.30–09.50 UInformal patient payments: evidence and dilemmas Tetiana Stepurko, National University of Kyiv-Mohyla Academy, Kyiv, Ukraine 09.50–10.10 Discussion 10.10–10.30 Unofficial payments of medical care in Russia Sergey Shishkin, National Research University Higher School of Economics, Moscow 10.30–10.50 Discussion 10.50–11.10 Managing conflicts of interest in healthcare Sarah Steingrüber, Curbing Corruption, Canada 11.10–11.30 Discussion 12.30–14.00 Break

14.30–18.00 SPOT: lifehacks for young oncologists

Chairs: Gilberto Morgan, University of Texas MD Anderson Cancer Center, Houston, USA Matteo Lambertini, San Martino Hospital, University of Genova, Genoa, Italy Nicholas Pavlidis , Ioannina University, Ioannina, Greece Evgenia Kharchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Saint-Petersburg Galina Kireeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Saint-Petersburg 14.30–14.50 Career development for young oncologists Nicholas Pavlidis, Ioannina University, Ioannina, Greece 14.50–14.55 Discussion

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Hall Green 5

14.55–15.15 Oncology in the era of social media Gilberto Morgan, University of Texas MD Anderson Cancer Center, Houston, USA 15.15–15.20 Discussion 15.20–15.40 Evidence-based surgery vs Practical surgery Aisha Isaeva, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 15.40–15.45 Discussion 15.45–16.05 Doctor-patient communication Anastasia Danilova, Moscow City Oncology Hospital № 62, Moscow 16.05–16.10 Discussion 16.10–16.30 How to initiate Your clinical study Matteo Lambertini, San Martino Hospital, University of Genova, Genoa, Italy 16.30–16.35 Discussion 16.35–16.55 How to make good presentation Evgenia Kharchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Saint-Petersburg 16.55–17.00 Discussion 17.00–17.20 How to write and publish an article Galina Kireeva , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Saint-Petersburg 17.20–17.25 Discussion 17.25–17.45 Cancer prevention Gilberto Morgan, University of Texas MD Anderson Cancer Center, Houston, USA 17.45–18.00 Discussion

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Hall Green 6+7

09.00–17.30 Multidisciplinary approach in oncogynecological diseases radiology

09.00–10.30 Session 1. Cervical cancer Chairs: Andrey Mishchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Anna Sidoruk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.00–09.15 Cervical cancer: pathoanatomy for a radiologist Anna Nuganen, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.15–09.30 Key issues in treatment tactics determination: expectations towards a radiologist Nikolay Bondarev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.30–09.50 Role of MRI in the diagnosis of primary cervical cancer Teresa Margarida Cunha, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal 09.50–10.10 Efficiency forecast and monitoring of treatment for cervical cancer through radiology methods Irina Trofimenko, Scientific and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Healthcare Department of Moscow, Moscow 10.10–10.30 Discussion 10.30–11.00 Break 11.00–12.30 Session 2 Hysterocarcinoma Chairs: Irina Trofimenko, Scientific and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Healthcare Department of Moscow, Moscow Nikolay Bondarev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.00–11.15 Hysterocarcinoma: pathoanatomy for a radiologist Stanislav Tolmachev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.15–11.30 Key issues in treatment tactics determination: how does a radiologist help? Apparent perspectives and global challenges Anna Sidoruk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.30–11.50 MRI staging of Endometrial Cancer: ESUR Guidelines, 2018 Teresa Margarida Cunha, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal 11.50–12.10 Capabilities and perspectives of multiparameter ultrasound imaging in hysterocarcinoma diagnostics Irina Meshkova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.10–12.30 Discussion 12.30–14.00 Break

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Hall Green 6+7

14.00–15.30 Session 3. Ovarian tumors Chairs: Irina Meshkova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Konstantin Guseinov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.00–14.20 Ovarian tumors: pathoanatomy for a radiologist Anna Khokhlova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.20–14.50 Differential diagnosis of ovarian tumors: mpMRI (O-RADS: pros and cons) Lucia Manganaro, Sapienza University of Rome, Rome, Italy 14.50–15.10 Differential diagnostics of ovarian masses: capabilities and perspectives of multiparameter ultrasound imaging Marina Chekalova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.10–15.30 Discussion 15.30–16.00 Break 16.00–17.30 Session 4. Peritoneal carcinomatosis Chairs: Marina Chekalova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Konstantin Guseinov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.00–16.15 Carcinomatosis: pathoanatomy for a radiologist Anna Khokhlova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.15–16.30 Carcinomatosis: key issues in treatment tactics determination Konstantin Guseinov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.30–16.50 CT and MRI in the follow up and recurrence of ovarian cancer Lucia Manganaro, Sapienza University of Rome, Rome, Italy 16.50–17.10 CT and MRI evaluation of lesions: critical areas and severity scales Ksenia Kozyreva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 17.10–17.30 Discussion

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Hall Green 8

08.30–12.30 Cutaneous melanoma: new approaches to treatment

Chairs: Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Lev Demidov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Georgy Gafton, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Daniil Stroyakovskiy, Moscow city oncology hospital № 62, Moscow 08.30–08.50 Problems of medical care provision to patients with skin melanoma in the Russian Federation Igor Samoilenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.50–08.55 Discussion 08.55–09.15 TNM8 and signaling lymph nodes biopsy. Practical value for management in routine clinical practice Grigory Zinoviev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.15–09.20 Discussion 09.20–09.40 What to expect from a morphological examination? Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.40–09.45 Discussion 09.45–10.05 What to expect from a molecular genetic testing? Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.05–10.10 Discussion 10.10–10.30 Early stages adjuvant therapy: is it necessary? Galina Kharkevich, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.30–10.35 Discussion 10.35–10.55 Stage III adjuvant therapy: real opportunities in the Russian Federation Daniil Stroyakovskiy, Moscow city oncology hospital № 62, Moscow 10.55–11.00 Discussion 11.00–11.20 How to treat a metastatic form? Immune therapy: pros and cons Anna Semenova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.20–11.25 Discussion 11.25–11.45 How to treat a metastatic form? Target therapy: pros and cons Irina Koroleva, State Budgetary Healthcare oncology center for Samara region, Samara

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Hall Green 8

11.45–11.50 Discussion 11.50–12.10 Prospects for skin melanoma treatment Aleksey Novik, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.10–12.30 Discussion 12.30–14.00 Sponsor symposium lunch** ** (Not included in the CME program)

14.00–16.00 Cancer service development perspectives within the framework of the «Healthcare» national project

Chairs: Andrey Kaprin, FSBI NMRRC of the Ministry of Health of Russia, Moscow Ivan Stilidi, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation», Moscow Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Moderator: Irina Laricheva, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 14.00–14.15 Indicators monitoring system for the malignant tumors fight federal project Irina Laricheva, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 14.15–14.20 Discussion 14.20–14.40 Digital loop in oncology Inna Ashenbrenner, «AO BARS-Group», Moscow 14.40–14.45 Discussion 14.45–15.05 Provision of a medical organization with qualified personnel Nadezhda Nesvetaylo, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 15.05–15.10 Discussion 15.10–15.40 Medical services export. Existing opportunities for oncology centers Anastasia Radyukina, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 15.40–15.50 Discussion

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Hall Green 8

16.00–18.00 Analysis of the KSG system. Subtotals

Chairs: Irina Laricheva, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow Olga Obukhova, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 16.00–16.15 Analysis of changes in the oncological service performance indicators and activities in Russia during a 10years’ period from 2008 to 2018 Anna Shahzadova, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 16.15–16.20 Discussion 16.20–16.35 Reform of the payment for medical care: conception and results Olga Obukhova, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 16.35–16.40 Discussion 16.40–17.05 Analysis of a medical institution economic benefits evaluation when choosing a treatment regimen Inna Zheleznyakova, FSBI «Center for Healthcare Quality Assessment and Control», Moscow 17.05–17.10 Discussion 17.10–17.30 International experience: a compromise between economics and quality Felicia Marie Knaul, The World Bank, Miami, USA 17.30–17.35 Discussion 17.35–17.55 Current status: audit of regional tariff agreements Natalia Pikovskaya, FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 17.55–18.00 Discussion

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HallЗал Green Blue 1 9

10.00–14.30 Workshop session «Live surgery»: head and neck tumors

Moderators: Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Maxim Kotov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.00–12.30 Transoral laser resection of laryngeal cancer with a CO laser - T1N0M0 (FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation) Surgeon: Ali Mudunov 12.30–13.00 Break 13.00–14.30 Signal LNs biopsy for tongue cancer with the use of a gamma sensor. Cryosurgery of a tongue tumor (FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation) Surgeon: Zamira Radjabova

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Hall Green 10

08.00–16.30 New challenges for fight against cancer

08.00–11.20 Session 1. HPV associated tumors spread control Chairs: Elisabete Weiderpass, International Agency for Research on Cancer, Lyon, France David Zaridze, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Maribel Almonte, International Agency for Research on Cancer, Lyon, France 08.00–08.15 Economic losses due to cancer in Russia (Sponsored by a company*. Not included in the program for NMOs) Anton Barchuk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.15–08.20 Discussion 08.20–08.35 Trends and new challenges for cancer control in Russia (Sponsored by a company*. Not included in the program for NMOs) Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.35–08.40 Discussion 08.40–08.55 HPV burden in Russia (Sponsored by a company*. Not included in the program for NMOs) Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.55–09.00 Discussion 09.00–09.15 Cervical cancer control: history and future directions Ahti Anttila, Finnish Cancer Registry, Helsinki, Finland 09.15–09.20 Discussion 09.20–09.35 Basic facts about HPV and its role in human cancers Vitaly Smelov, International Agency for Research on Cancer, Lyon, France 09.35–09.40 Discussion 09.40–09.55 PAP or HPV for cervical cancer screening? Isabelle Heard, National HPV Reference Laboratory, Institut Pasteur, Paris, France 09.55–10.00 Discussion 10.00–10.20 Break 10.20–10.35 Is it time to implement HPV testing for primary screening in low resource settings? Maribel Almonte, International Agency for Research on Cancer, Lyon, France 10.35–10.40 Discussion

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Hall Green 10

10.40–10.55 Frontline biomarkers for cervical lesions in the era of HPV-based screening Karin Sundström, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden 10.55–11.00 Discussion 11.00–11.15 Initial results of population based cervical cancer screening program using HPV testing in one million Turkish women Murat Gultekin, Hacettepe University, Ankara, Turkey 11.15–11.20 Discussion 11.20–11.40 Break 11.40–13.00 Session 2 Primary prevention of HPV associated tumors Chairs: Ahti Anttila, Finnish Cancer Registry, Helsinki, Finland Karin Sundström , Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden 11.40–12.15 HPV vaccination – summary of current evidence Mark Arbyn, Unit of Cancer Epidemiology, Belgian Cancer Centre, Brussels, Belgium 12.15–12.20 Discussion 12.20–12.35 HPV primary prevention in practice Penelope Gray, Tampere University, Tampere, Finland 12.35–12.40 Discussion 12.40–12.55 Cancer and HIV Isabelle Heard, National HPV Reference Laboratory, Institut Pasteur, Paris, France 12.55–13.00 Discussion 13.00–14.00 Break 14.00–14.30 Session 3. Lecture of a Director of International Cancer Research Agency Chairs: Aleksey Belyaev , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Ahti Anttila, Finnish Cancer Registry, Helsinki, Finland 14.00–14.25 From research to action: global discrepancies in cancer control Elisabete Weiderpass , International Agency for Research on Cancer, Lyon, France 14.25–14.30 Discussion 14.30–14.50 Break

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Hall Green 10

14.50–16.30 Session 4. Nutrition and cancer Chairs: Vitaly Smelov, International Agency for Research on Cancer, Lyon, France David Zaridze, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Malcolm Moore, Khon Kaen University, Khon Kaen, Thailand 14.50–15.15 Prevention of gastric cancer Rolando Herrero, International Agency for Research on Cancer, Lyon, France 15.15–15.20 Discussion 15.20–15.45 Diet, microbiome and cancer Inge Huybrechts, International Agency for Research on Cancer, Lyon, France 15.45–15.50 Discussion 15.50–16.05 Nutrition and cancer mortality in China You-lin Qiao, Chinese Academy of Medical Sciences & Peking Union Medical College, Peking, China 16.05–16.10 Discussion 16.10–16.25 Nutrition and cancer in South Korea Keun-Yong Yoo, Seoul National University, Seoul, South Korea 16.25–16.30 Discussion

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Hall Red 8+9

09.00–16.20 Molecular oncourology

09.00–12.10 Session 1 Chairs: Oleg Karyakin, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk Boris Alekseev, FSBI NMRRC of the Ministry of Health of Russia, Moscow Vsevolod Matveev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.00–09.05 Opening 09.05–09.25 Molecular diagnostic systems in oncourology Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.30–09.50 A new approach tumor metastatic potential suppression: tumor dissemination collective mechanism inhibition Gulnara Tuguzbayeva, FSBEI Bashkir State Medical University of the Ministry of Health of Russia, Ufa 09.55–10.15 Role of intracellular and secreted (extracellular) microRNA in oncourological diseases development Anastasia Malek, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.20–10.40 Capabilities of prostate cancer patients treatment diagnostics/ monitoring through microRNA analysis in circulating prostate-specific exosomes Nadezhda Nikiforova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.45–11.00 Role of microRNA in testicular germ cell tumors Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.05–11.20 Role of microRNA in renal cell carcinomas development Irina Gilyazova, FSBEI Bashkir State Medical University of the Ministry of Health of Russia, Ufa 11.25–11.45 Prospects for tissue microarrays use in molecular genetic analysis on the example of prostate cancer Maria Berkut, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.45–12.00 Discussion 12.00–12.10 Closing remarks 12.30–14.00 Sponsor symposium lunch** ** (Not included in the CME program)

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Hall Red 8+9

14.00–16.40 Session 2 14.00–14.15 Intraoperative detection of sentinel lymph nodes metastases in patients with prostate cancer Boris Alekseev, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 14.20–14.35 Molecular genetic markers for prostate cancer diagnosing and prediction Vladimir Nazarov, Pavlov First St.Petersburg State Medical University, St. Petersburg 14.40–14.55 Autoantibodies to visual arrestin as kidney cancer markers Andrey Zamyatin, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 15.00–15.15 Role of PD-L1 expression in metastatic kidney cancer patients Pavel Borisov, St. Petersburg City clinical oncology center, St. Petersburg 15.20–15.35 Androgen dependent signaling pathway and androgen deficiency Renat Guspanov, First city hospital named after N.I. Pirogov, Moscow 15.40–15.55 Androgen dependent signaling pathwa and prostate cancer (Sponsored by a company*. Not included in the program for NMOs) Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.00–16.15 Aquaporin 3 - AQP3 gene expression in bladder cancer patients Ksenia Danilko, FSBEI Bashkir State Medical University of the Ministry of Health of Russia, Ufa 16.15–16.30 Discussion 16.30–16.40 Closing remarks

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Hall Red 10

09.00–18.00 Outpatient oncology

Chairs: Alfia Khasanova, Tatarstan Republic Cancer Center, Kazan Boris Kasparov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.00–09.10 Outpatient surgery in gynecologic oncology Olga Lavrinovich, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.10–09.20 Peculiarities of examination of patients with testicular masses in outpatient stage Oleg Zaozersky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.20–09.25 Discussion 09.25–09.35 Outpatient therapeutic endoscopy. A private clinic experience Alexey Makushkin, «Medsi» clinic, Moscow 09.35–09.40 Discussion 09.40–09.50 Somatoform disorders psychotherapy in oncological patients in outpatient settings Kristina Kondratieva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.50–09.55 Discussion 09.55–10.05 Creating an outpatient oncology clinic: experience of the federal cancer center Nikita Kozyavin, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.05–10.10 Discussion 10.10–10.20 Telemedicine health care service: experience of FSBI N.N.Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation Anna Malkova , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.20–10.25 Discussion 10.25–10.35 Opportunities of skin tumors diagnostics and outpatient treatment Maria Ebert, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.35–10.40 Discussion 10.40–10.50 Immunotherapy in outpatient settings Anton Krutov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.50–10.55 Discussion

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Hall Red 10

10.55–11.05 International and domestic experience of a multidisciplinary team work Evgenia Kharchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.05–11.10 Discussion 11.10–11.20 Role of nurse in MDT meeting Susan Newton, Daniel Kelly, Banner University of Arizona Medical Center, Royal College of Nursing Chair of Nursing Research, USA, UK 11.20–11.25 Discussion 11.25–11.45 Gastroenterological aspects of cancer patients management in an outpatient stage Polina Zakharova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.45–11.50 Discussion 11.50–12.00 Rehabilitation of rectal carcinoma patients. Experience of FSBI N.N.Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation Anna Alekseenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.00–12.05 Discussion 12.05–12.15 Drug-induced polyneuropathy: diagnosis and treatment Vladislav Andreev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.15–12.20 Discussion 12.20–12.30 Spasticity treatment and rehabilitation for spinal tumours and spinal cord tumours in children Vladislav Andreev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program) 14.00–14.10 Drug antitumor therapy nephrotoxicity Ksenia Molchanova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.10–14.15 Discussion 14.15–14.35 The first RF program of outpatient nutritional support to oncological patients: problems, successes, intermediate results Tatiana Ostrinskaya, St. Petersburg City clinical oncology center, St. Petersburg 14.35–14.40 Discussion 14.40–14.50 Outpatient chemotherapy international experience Aykui Geokchyan-Kzhdryan, Erebuni MC, Yerevan, Armenia 14.50–14.55 Discussion

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Hall Red 10

14.55–15.10 Exercise therapy in the rehabilitation of breast cancer patients at outpatient stage Margarita Zernova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.10–15.15 Discussion 15.15–15.30 Immunotherapy with autologous dendritic cells in cancer patients treatment with the standard treatment options exhausted: 20-years experience of FSBI N.N.Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation Irina Baldueva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.30–15.35 Discussion 15.35–15.45 The use of Duloxetine for polyneuropathy caused by drug antitumor therapy (case report) Elena Tkachenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.45–15.50 Discussion 15.50–16.10 Skin toxicity correction methods for cancer patients Svetlana Klyuchareva, North-western State Medical University named after I.I.Mechnikov, St. Petersburg 16.10–16.15 Discussion 16.15–16.35 Osteomodifying agents and early breast cancer Lyudmila Manzyuk, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Moscow 16.35–16.40 Discussion 16.40–17.00 Osteomodifying agents and metastatic breast cancer Alfia Khasanova, Tatarstan Republic Cancer Center, Kazan, Republic of Tatarstan 17.00–17.05 Discussion 17.05–17.25 What changed in accompanying therapy for cancer patients management Irina Koroleva, State Budgetary Healthcare oncology center for Samara region, Samara 17.25–17.30 Discussion 17.30–17.40 Value of radiotherapy in prostate cancer treatment Roman Novikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 17.40–17.45 Discussion 17.45–17.55 Current radiotherapy methods in breast cancer treatment Zhanna Bryantseva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation St. Petersburg 17.55–18.00 Discussion

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Hall Red 11

09.00–18.00 Diagnostic and treatment process safety: contribution of a nurse

09.00–12.30 Session 1. Organization of nursing: experience of the United States of America and the European Union Chairs: Daniel Kelly, Royal College of Nursing Chair of Nursing Research at Cardiff University, Cardiff, UK Susan Newton, RN, MS, AOCN, AOCNS, Dayton, USA Jane Lacovara, University of Arizona Medical Center, Tucson, USA Johan De Munter, EONS, Brussel, Belgiu Evgenia Kharchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Galina Kireeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Irina Tolmacheva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.00–09.30 Introduction Daniel Kelly, Royal College of Nursing Chair of Nursing Research at Cardiff University, Cardiff, UK Susie Newton, RN, MS, AOCN, AOCNS, Dayton, USA 09.30–10.20 Prevention, control and management of infections in oncology settings Jane Lacovara, University of Arizona Medical Center, Tucson, USA 10.20–10.25 Discussion 10.25–10.45 Break 10.45–11.40 Infusion-related responses to anticancer drugs (what nurses can do for management, evidence-based evaluation and interventions) Johan De Munter, EONS, Brussel, Belgium 11.40–11.45 Discussion 11.45–12.30 Professional development of nursing in oncology Daniel Kelly, Royal College of Nursing Chair of Nursing Research at Cardiff University, Cardiff, Great Britain 12.30–14.00 Break 14.00–18.00 Session 2. Role of a nurse in safety ensuring throughout diagnostic and treatment process Chairs: Valery Samoilenko, Russian Nurses Association, St. Petersburg Galina Solopova, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow Olesya Ignatova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Irina Tolmacheva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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Hall Red 11

14.00–14.10 Prevention of catheter-associated infections in cancer patients with prolonged vascular access Irina Guseva, FSBHI Clinical Hospital № 122 named after L.G. Sokolov under Federal Bio-Medical Agency of Russia, St. Petersburg 14.10–14.15 Discussion 14.15–15.00 Infection control in an oncohematological hospital Galina Solopova, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology , Moscow 15.00–15.05 Discussion 15.05–15.30 Do no harm! Larisa Zueva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.30–15.35 Discussion 15.35–15.55 Safety of a nurse working with cytostatics Elena Larionova, Bugetary Healthcare Institution for Omsk region «CIty clinical oncology center», Omsk 15.55–16.00 Discussion 16.00–16.40 Responsibility of a nurse Valery Samoilenko, Russian Nurses Association, St. Petersburg 16.40–16.45 Discussion 16.45–17.05 Role of nursing staff in the infections epidemiological surveillance system in the field of surgical intervention Elena Myasnikova, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St. Petersburg 17.05–17.10 Discussion 17.10–17.30 Involving parents in the safe process of treating children Ekaterina Muraveva, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation», Moscow 17.30–17.35 Discussion 17.35–17.55 Essentials of conflict-free communication. Aggression management principles. Anna Kan, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.55–18.00 Discussion

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Hall Blue 1

JUNE, 21, FRIDAY

09.30–13.00 Workshop session «Live surgery»: lung cancer

Moderators: Andrey Ryabov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Nikolay Krotov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.30–13.00 Bronchoangioplastic lobectomy / resection of the trachea bifurcation with «Y»-shaped reconstruction of bifurcatio tracheae (FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Surgeon: Evgeny Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.30–13.00 VATS lobectomy (FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation) Surgeon: Pavel Kononets, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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Hall Blue 2

09.00–18.20 Pancreatic tumours

09.00–11.30 Session 1

Chairs: Sergey Bagnenko, Pavlov First St. Petersburg State Medical University, St.Petersburg Alexey Karachun, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Martin E. Kreis, Charité – Universitätsmedizin Berlin, Berlin, Germany Igor Hatkov, A.S. Loginov Moscow clinical scientific center, Moscow

09.00–09.25 Variant anatomy of pancreas Ivan Gaivoronskiy, S.M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation, St.Petersburg

09.25–09.50 Pancreatic tumors: what surgeons may require from a diagnostics radiologist Kirill Petrov, «Medskan» network of medical centers, Moscow

09.50–10.15 Transpapillary interventions for periampullary tumors: arguable points Yulia Kulezneva, A.S. Loginov Moscow clinical scientific center, Moscow

10.15–10.40 Capabilities of endoscopic method in the diagnosis and treatment of pancreatic tumors Lyudmila Marinova, FSBI «A.V. Vishnevskiy NMRC of surgery» of the Ministry of Defense of the Russian Federation, Moscow

10.40–11.05 Complex morphological diagnosis of pancreatic pathology based on materials of endoscopic ultrasonography with FNA Sergey Vorobyov, National Center for Clinical Morphological Diagnosis, St.Petersburg

11.05–11.30 Discussion

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program)

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Hall Blue 2

14.00–16.20 Session 2

Chairs: Bogdan Kotiv, S.M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation, St.Petersburg Vyacheslav Yegorov, Ilinskaya hospital, Moscow Aleksander Pavlovskiy, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg

14.00–14.25 Non-epithelial tumors of pancreas Martin E. Kreis, Charité – Universitätsmedizin Berlin, Berlin, Germany

14.25–14.50 Minimally invasive surgery for pancreatic tumors Igor Hatkov, A.S. Loginov Moscow clinical scientific center, Moscow

14.50–15.15 Important «Tips and Tricks» of pancreaticoduodenectomy, or how to make an operation safe Vladimir Zagainov, FBHI VDMC FMBA of Russia, Nizhny Novgorod

15.15–15.40 Pancreatodigestive anastomosis - an unsolved problem in pancreatic surgery Rodion Rasulov, SBHI «Regional cancer center», Irkutsk

15.40–16.05 Surgical technologies and combined treatment of borderline resectable cancer of the head of the pancreas Denis Kuchin, FBHI VDMC FMBA of Russia, Moscow

16.05–16.20 Break

16.20–18.20 Session 3

Chairs: Rodion Rasulov, SBHI «Regional cancer center», Irkutsk Andrey Pryadko, Leningrad Regional Clinical Hospital, St.Petersburg

16.20–16.45 Oncological, surgical and regional hemodynamic effects of distal pancreatectomy with celiac trunk resection. Lessons of 30 surgeries Vyacheslav Yegorov, Ilinskaya hospital, Moscow

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Hall Blue 2

16.45–17.10 Non-fanction neuroendocrine pancreatic tumors. Sporadic and associated with syndromes. Surgery or monitoring? Roman Petrov, SBHI Bakhrushin brothers City clinical hospital of the Moscow healthcare department, Moscow

17.10–17.35 Hypofractionated ablative radiotherapy improves survival in locally advanced pancreatic cancer Mariya Reyngold, Memorial Sloan Kettering Cancer Center, New York, USA

17.35–18.00 Neoadjuvant therapy of pancreatic cancer. State of the art and perspectives Aleksander Pavlovskiy, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg

18.00–18.20 Discussion

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Hall Blue 3

09.00–17.30 ESGO, RSGO joint session

09.00–09.10 ESGO, RSGO joint session opening remarks Adiliya Urmancheeva , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Christhardt Kohler, Asklepios Hospital, Hamburg, Germany Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Frederic Amant, Center for Gynecological Oncology, Amsterdam, Netherlands Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–11.30 Surgery in cervical cancer Chairs: Murat Gultekin, Ankara Hacettepe University, Ankara,Turkey Frederic Amant, Center for Gynecological Oncology, Amsterdam, Netherlands Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–09.30 Phase III randomized trial of laparoscopic or robotic radical hysterectomy vs. abdominal radical hysterectomy in patients with early- stage cervical cancer: LACC trial a critical interpretation of the results and impact on future surgical practice Pedro Ramirez, The University of Texas MD Anderson Cancer Center, Houston, USA 09.30–09.35 Discussion 09.35–09.55 Unexpected outcome in LACC study - are there any potential alternative explanations for the association with MIS Christhardt Kohler, Asklepios Hospital, Hamburg, Germany 09.55–10.00 Discussion 10.00–10.20 Practice of laparoscopic surgery for cervical cancer: FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.20–10.25 Discussion 10.25–10.45 Practice of cervical cancer laparoscopic surgery: FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Aleksey Shevchuk, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.45–10.50 Discussion 10.50–11.10 Fertility-sparing surgery in cervical cancer (radical trachelectomy) Gloria Salvo, MD Anderson Cancer Center, Houston, USA 11.15–11.25 Discussion

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Hall Blue 3

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Break 14.00–17.30 Combined treatment of cervical cancer Chairs: Elena Novikova, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Dilyara Kaydarova, Kazakh Oncology and Radiology Research Institute, Almaty, Kazakhstan 14.00–14.20 Cancer and pregnancy Frederic Amant, Center for Gynecological Oncology, Amsterdam, Netherlands 14.20–14.25 Discussion 14.25–14.45 Neoadjuvant systemic chemotherapy in the combined treatment of cervical cancer Aleksandra Tyulyandina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.45–14.50 Discussion 14.50–15.05 Neoadjuvant regional chemotherapy in the combined treatment of cervical cancer Anna Kedrova , Federal research and clinical center for specialized types of medical care and medical technologies of the Federal Medical-Biological Agency, Moscow 15.05–15.10 Discussion 15.10–15.25 Surgery in combined treatment of locally advanced cervical cancer Sergey Maхimov, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St.Petersburg 15.25–15.40 Discussion 15.40–16.00 Break 16.00–17.30 Chairs: Dina Kurdiani, Tbilisi Cancer Center, Tbilisi, Georgia Svetlana Khokhlova, FBSI Science Center for obstetrics, gynecology and perinatology named after academician V.I. Kulakov, Moscow Larisa Kolomiets, Cancer Research Institute of Tomsk NRMC, Tomsk 16.00–16.20 The history and development of pelvic exenteration for recurrent cervical cancer Nadeem R. Abu-Rustum, Memorial Sloan Kettering Cancer Center, New- York, USA 16.20–16.25 Discussion

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Hall Blue 3

16.25–16.45 Сhemoradiotherapy for cervical cancer Lyudmila Krikunova, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 16.45–16.50 Discussion 16.50–17:10 Medical treatment of cervical cancer Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.10–17.15 Discussion 17.15–17.30 Conclusion

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Hall Blue 4+5

08.30–11.30 Session of Russian Association of Oncological Mammology

Chairs: Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Ruslan Paltuyev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Georgy Manihas, Pavlov First Saint Petersburg State Medical University, St. Petersburg 08.30–08.50 Research work of Russian Association of Oncological Mammology «Determination research data set (diagnostic methods and biological markers), allowing to refuse lymphadenectomy in case of breast cancer» Petr Krivorotko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.50–09.10 Review and analysis of the most significant recommendations and innovations in the breast cancer immunohistochemical test research Asel Kudaibergenova , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.10–09.30 Review of the most important recommendations and analysis of innovations in the surgical treatment of breast cancer over the past 5 years Vladislav Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.30–09.50 Review and analysis of the most significant recommendations and innovations in the systemic treatment of breast cancer over the past five years Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.50–10.10 Discussion 10.10–10.30 Review of expert reports and voting results Вreast - Gynecological & Immunooncology International Cancer Conference Hesham Elghazaly, Medical research center of Ain Shams University Faculty medicine, Cairo, Egypt 10.30–10.50 16th International Conference on Breast Cancer ( St. Gallen, 2019). Key recommendations for treatment Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.50–11.30 Discussion

Official opening of the V St. Petersburg International Onco- 11.30–12.30 logical Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program)

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Hall Blue 4+5

14.00–18.00 The Fifth M. L.Gershanovich Conference «Breast cancer - Personalized Cancer Therapy: from science to practice» with interactive voting

14.00–15.55 What influences the adjuvant drug therapy choice: age, stage or a tumor biology? Expert panel: Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Lyudmila Zhukova, SBHI A.S. Loginov Moscow clinical scientific center of Moscow Healthcare department, Moscow Petr Krivorotko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Мatteo Lambertini, Azienda Ospedaliera Universitaria San Martino di Genova, Genova, Italy Daniil Stroyakovskiy, SBHI Moscow city oncology hospital №62 of the Moscow Healthcare Department, Moscow 14.00–14.20 Breast cancer adjuvant drug therapy and fertility Мatteo Lambertini, Azienda Ospedaliera Universitaria San Martino di Genova, Genova, Italy 14.20–14.25 Discussion 14.25–14.45 Selection of adjuvant systemic therapy of triple negative breast cancer Lyudmila Zhukova, SBHI A.S. Loginov Moscow clinical scientific center of Moscow Healthcare department, Moscow 14.45–14.50 Discussion 14.50–15.15 Selection of adjuvant systemic therapy of HER2+ breast cancer Irina Kolyadina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation 15.15–15.20 Discussion 15.20–15.40 Selection of adjuvant systemic therapy of luminal breast cancer Daniil Stroyakovskiy, SBHI Moscow city oncology hospital № 62 of the Moscow Healthcare Department, Moscow 15.40–15.55 Discussion 15.55–18.00 Can metastatic breast cancer be cured? Expert panel: Sibylle Loibl, GBG Forschungs GmbH, Neu-Isenburg, Germany Nikolay Zhukov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow Marina Stenina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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Hall Blue 4+5

15.55–16.20 Prospects of HR + HER2-metastatic breast cancer treatment Sibylle Loibl, GBG Forschungs GmbH, Neu-Isenburg, Germany 16.20–16.25 Discussion 16.25–16.45 Prospects in metastatic triple negative breast cancer treatment (Sponsored by a company*. Not included in the program for NMOs) Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.45–16.50 Discussion 16.50–17.10 Present and future of metastatic HER2 + breast cancer therapy Marina Stenina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.10–17.15 Discussion 17.15–17.40 Can metastatic breast cancer be cured? Nikolay Zhukov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 17.40–17.45 Discussion 17.45–18.00 Closing remarks 18.00–19.30 Sponsor symposium lunch** **(Not included in the CME program)

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Hall Green 5

09.00–17.30 Cardio-oncology 09.00–11.30 Session 1 Chairs: Vera Potievskaya, FSBI NMRRC of the Ministry of Health of Russia Moscow Simon Matskeplishvili, M.V. Lomonosov MSU Medical Scientific Educational Center, Moscow Mehman Niyazi Mamedov, FSBI «National Medical Research Center for Preventive Medicine» of the Ministry of Healthcare of the Russian Federation, Moscow Marina Balluzek, St. Petersburg State University, St. Petersburg 09.00–09.20 Cardio-oncology - a new medical discipline Simon Matskeplishvili, M.V. Lomonosov MSU Medical Scientific Educational Center, Moscow 09.20–09.25 Discussion 09.25–09.45 Prospects for the prevention and treatment of cardiac diseases in cancer patients Vera Potievskaya, FSBI NMRRC of the Ministry of Health of Russia, Moscow 09.45–09.50 Discussion 09.50–10.10 Cardiovascular and oncological diseases: common risk factors Mehman Niyazi Mamedov, FSBI «National Medical Research Center for Preventive Medicine» of the Ministry of Healthcare of the Russian Federation, Moscow 10.10–10.15 Discussion 10.15–10.35 Cardiac oncology as a component of oncology rehabilitation: state-of- the-art and development prospects Marina Balluzek, St. Petersburg State University, St. Petersburg 10.35–10.40 Discussion 10.40–11.00 Radiation therapy and heart: complications, prevention and treatment prospects Maria Poltavskaya, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow

11.00–11.30 Discussion

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Hall Green 5

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–13.30 MELANOMA.PRO domestic research *(Not included in the CME program) Chairs: Lev Demidov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.30–12.40 Neoadjuvant intratumoral anti-PD1 therapy in patients with stage III- IVM1a skin melanoma: a pilot study Ekaterina Shakhray, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.40–12.50 4 years’ results of ipilimumab expanded access program in Russia Galina Kharkevich, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.50–13.00 Cell therapy in patients with cutaneous melanoma. Irina Baldueva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.00–13.10 Russian observational practice of targeted therapy in skin melanoma patients (ADMIRE) Kristina Orlova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.10–13.20 In-house experience of triple combination use in patients with metastatic melanoma Natalia Zhukova, St.-Petersburg City Oncology Clinic, St. Petersburg 13.20–13.30 Discussion 14.00–17.30 Cardio-oncology 14.00–17.30 Session 2 Chairs: Vera Potievskaya, FSBI NMRRC of the Ministry of Health of Russia, Moscow Larisa Bolotina, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow David Dundua, Further training institution of Academy for postgraduate education of the federal state budgetary institution «federal research and clinical center for specialized types of medical care and medical technologies of the Federal Medical-Biological Agency, Moscow 14.30–14.45 Percutaneous coronary interventions in cancer patients David Dundua , Further training institution of Academy for postgraduate education of the federal state budgetary institution «federal research and clinical center for specialized types of medical care and medical technologies of the Federal Medical-Biological Agency, Moscow

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Hall Green 5

14.45–14.50 Discussion 14.50–15.05 Endovascular interventions in patients with cancer and cardiac pathology combined Igor Kochanov, Clinic named after Peter the Great, St. Petersburg 15.05–15.10 Discussion 15.10–15.25 Organization of an X-ray surgery department in order to provide cardiologic cardiac care to cancer patients in an oncology facility Valery Kucherov, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 15.25–15.30 Discussion 15.30–15.45 Cardiovascular adverse events in cancer patients treatment Larisa Bolotina, P. A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 15.45–15.50 Discussion 15.50–16.05 Experimental validation of the clinical use of mesenchymal stromal cells in case of cardiotoxic effects in antitumor therapy Olga Popovkina, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 16.05–16.10 Discussion 16.10–16.25 Experimental validation of protective and regenerative action of mesenchymal stem cells in anthracyclines-induced cardiomyopathies Lyudmila Grivtsova, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 16.25–16.30 Discussion 16.30–16.45 Predictive benefits of ST-2 marker in cardiotoxicity assessment Marina Poluektova, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 16.45–16.50 Discussion 16.50–17.05 Monitoring and possibilities of cardiotoxicity correction in breast cancer patients undergoing anthracycline-containing chemotherapy Elena Sycheva, Rostov research institute of oncology of the MoH of Russia, Rostov-on-Don 17.05–17.10 Discussion 17.10–17.25 Features of the venous thromboembolic complications treatment in oncology, anticoagulant therapy selection Oksana Katelnitskaya, Rostov research institute of oncology of the MoH of Russia, Rostov-on-Don 17.25–17.30 Discussion

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08.00–11.00 Organization of cancer care in the Russian Federation Chairs: Andrey Kaprin, FSBI NMRRC of the Ministry of Health of Russia, Moscow Ivan Stilidi, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Andrey Karitskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.00–08.05 Opening speech Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.05–08.20 Fight against cancer diseases: domestic and foreign experience Andrey Kaprin , FSBI NMRRC of the Ministry of Health of Russia, Obninsk 08.20–08.35 Topic to be announced Ivan Stilidi, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.35–08.50 State of cancer care in Russia Valery Starinskiy, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 08.50–09.05 Active detection of malignant tumours in the framework of clinical examination program. Work experience, results, issues Rustem Hasanov, Kazan State Medical Academy - branch of FSBEI for Additional Professional Education of Russian Medical Academy Continuous Professional Education under Ministry of Health of the Russian Federation, Kazan, Republic of Tatarstan 09.05–09.20 Organization of cancer care in the St.Petersburg Georgy Manihas, Pavlov First St.Petersburg State Medical University, St. Petersburg 09.20–09.35 Organization of multidisciplinary patient rehabilitation oncology profile Roman Filatov, JSC «Medicine», Moscow 09.35–09.50 Experience in cancer care service assessment of FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Yuri Komarov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.05–10.20 Optimization of examination and treatment terms for cancer patients in the Tomsk region Sofia Mazeina, RSBHI «Tomsk Regional cancer center», Tomsk 10.20–10.35 The experience of organizing cancer care in the Republic of Belarus Oleg Sukonko, N.N. Alexandrov National Cancer Centre of Belarus, Minsk, Republic of Belarus 10.35–11.00 Discussion

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Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Break 14.00–18.00 Organizational and legal aspects of cancer care in the Russian Federation (Not included in the CME program) Chairs: Andrey Karitskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Olga Zinovieva, Law office «Law bureau ONEGIN», St. Petersburg 14.00–14.05 Opening speech Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.05–14.30 Drug provision for cancer patients at outpatient and inpatient stages. The off-label prescription and use of drugs in oncology: order, peculiarities, risks Aleksey Nikolaev, Law office «Law bureau ONEGIN», St. Petersburg 14.30–14.55 Use of telemedicine services in cancer treatment: «doctor-doctor», «doctor-patient» Anna Medvedskaya, Law office «Law bureau ONEGIN», St. Petersburg 14.55–15.15 Informing patients in oncology Tatiana Zasedateleva , Law office «Law bureau ONEGIN», St. Petersburg 15.15–15.35 Legal regulation of biomedical cell products use Sofia Malakhova, Law office «Law bureau ONEGIN», St. Petersburg 15.35–16.00 Interaction of medical organizations and charitable foundations: features of legal regulation and legally significant document circulation, «gray» law areas Dmitry Bartrenev, Law office «Law bureau ONEGIN», St. Petersburg 16.00–16.25 Minimization of medical care provision risks in excess of the CHI established amounts: legal mechanisms, judicial practice Aleksey Nikolaev, Law office «Law bureau ONEGIN», St. Petersburg 16.25–16.45 Administrative and prosecutor’s inspections: protection of a medical organization and its officials Alena Fomina, Law office «Law bureau ONEGIN», St. Petersburg 16.45–17.05 Current trends in judicial practice in disputes related to the cancer treatment Olga Zinovieva, Law office «Law bureau ONEGIN», St. Petersburg 17.05–17.30 Criminal liability of a doctor, its limits and features: how a doctor can work quietly in a «killer doctors» restless trend Olga Zinovieva, aw office «Law bureau ONEGIN», St. Petersburg 17.30–18.00 Discussion

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08.20–11.25 Smoking and cancer

Chairs: David Zaridze, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Lev Bershtein, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Anton Barchuk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.20–08.35 Smoking and cancer in Russia David Zaridze, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.35–08.40 Discussion 08.40–08.55 Genetics of smoking Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.55–09.00 Discussion 09.00–09.15 Endocrinology and oncoendocrinology of smoking Lev Bershtein, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.15–09.00 Discussion 09.00–09.20 Break 09.20–09.35 Tobacco control and cancer prevention in Asia and the Pacific Region Malcolm Moore, Khon Kaen University, Khon Kaen, Thailand 09.35–09.40 Discussion 09.40–10.00 Smoking and cancer in western Asia Alireza Mosavi, Shahid Beheshti University of Medical Sciences, Tehran, Iran 10.00–10.20 Break 10.20–10.35 Prevention and screening programs launch for lung cancer in resource- poor countries Abhishek Shankar, All India Institute of Medical Sciences, Delhi, India 10.35–11.25 Discussion

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program) 14.00–18.00 Roundtable discussion with the participation of mass media (Not included in the CME program)

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09.00–18.00 «Live surgery» workshop session: endoscopy

Moderator: Mikhail Kuzmin-Krutetskiy, North-Western state Medical University named after I.I. Mechnikov, St. Petersburg 09.50–13.30 Live surgery Endoscopic submucosal dissection (FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation) Surgeon: Ohata Ken Endoscopic tunnel resection (FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation) Surgeon: Oleg Tkachenko 09.00–09.50 Operative bronchoscopy. Endoscopy capabilities in case of anastomotic dehiscence, bronchial fistulas, strictures. Vitaly Kurtukov, RSBHI City hospital № 5, Barnaul 09.50–10.20 Live surgery: broadcast from operating theatre 10.20–10.45 Strictures and gastrointestinal anastomotic dehiscence. Endoscopic treatment Aleksandra Sidorova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.45–11.15 Live surgery: broadcast from operating theatre 11.15–11.40 Position of FNA in difficult-to-verify tumors Evgeny Solonitsyn, FSBI Almazov National Medical research Center of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.40–12.10 Position of echo contrast enhancement in tumour diagnostics Elena Artamonova, A.S. Loginov Moscow clinical scientific center, Moscow 12.10–12.40 Live surgery: broadcast from operating theatre 12.40–13.10 ESD vs EPMR. View from Japan Hiroshi Kashida, Kindai University Faculty of Medicine, Osaka, Japan 13.10–13.30 Live surgery: broadcast from operating theatre 13.30–14.00 Difficult situations for ESD in colon Aleksander Smirnov, Pavlov First St.Petersburg State Medical University, St. Petersburg 14.00–14.30 Break

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14.30–14.50 Endoscopic fullwall resection of premalignant and malignant tumors in colon Armin Küllmer , University of Freiburg, Freiburg, Germany 14.50–15.10 Rules for endoscopic material provision to histological evaluation. Current rules for colorectal lesions evaluation (Mapping. Budding) Ekaterina Krainova, SBHI of the Yaroslavl region «Clinical oncology hospital», Yaroslavl 15.10–15.30 Eligibility of extended Japanese criteria for early gastric cancer endoscopic treatment. Endoscopic signs of deep invasion Ohata Ken, NTT Medical Center Tokyo, Tokio, Japan 15.30–15.50 Role of endoscopic ultrasonography in early gastric cancer treatment determination. Can we further extend the criteria for EGC? Marina Grinkevich, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.50–16.10 Current strategy for diagnosis and treatment of non-epithelial gastric tumors Olga Malihova , FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.10–16.30 Submucosal gastric tumours. Is it all so obvious in the diagnosis? Oleg Tkachenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.30–17.00 Discussion

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Neuroblastoma in children: promising diagnosis and 08.10–17.30 treatment directions

08.10–09.25 Session 1. Molecular genetic studies of primary neuroblastoma and tumor recurrence Chairs: Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Aleksandr Druy, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow Iedan R. Verly, Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands 08.10–08.35 Clinical significance of catecholamine metabolites determination in patients with neuroblastoma Iedan R. Verly, Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands 08.35–09.00 The Genetic Basis of Favorable Outcome and Fatal Tumor Progression in Neuroblastoma Sandra Ackermann, Department of Experimental Pediatric Oncology, University Children’s Hospital of Cologne, Koln, Germany 09.00–09.20 Genomic and expression aberrations as prognostic factors in neuroblastoma Aleksander Druy, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 09.20–09.30 Discussion 09.30–11.30 Session 2. Molecular methods of a tumour treatment efficacy and kinet- ics monitoring Chairs: Godelieve Andrea Maria Tytgat, Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands Aleksander Druy, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 09.30–09.55 Minimal residual disease detection in neuroblastoma: outcome of the German/Dutch NBL 2009 trial Godelieve Andrea Maria Tytgat, Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands 09.55–10.20 Liquid biopsies in pediatric solid tumors Lieke van Zogchel, Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands

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10.20–10.45 Molecular genetic methods in assessing bone marrow damage and minimal residual disease course in patients with neuroblastoma Varvara Brilliantova, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 10.45–11.10 Use of flow cytometry to assess bone marrow damage in case of neuroblastoma Aleksander Drui, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 11.10–11.30 Discussion

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Break 14.00–15.40 Session 3. Current approaches to neuroblastoma treatment in children Chairs: Svetlana Kuleva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Denis Kachanov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 14.00–14.15 Current aspects of neuroblastoma diagnostics and treatment in children Denis Kachanov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 14.15–14.30 Results of the neuroblastoma treatment according to protocol NB 2004 in the Republic of Belarus, optimization of approaches to high-risk groups treatment Inna Propleskovskaya, SI Republic Scientific and Practical Center for pediatric oncology, hematology and immunology, Minsk, Republic of Belarus 14.30–14.45 Clinical and prognostic value of radiation medicine methods in children with neuroblastoma Yuri Likar, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 14.45–15.00 Surgical approaches on case of neuroblastoma with various localization Dmitri Akhaladze, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 15.00–15.15 Minimally invasive surgeries in case of neuroblastoma Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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15.15–15.30 Current approaches to external radiation therapy in neuroblastoma complex treatment Aleksey Nechesnyuk, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 15.30–15.40 Discussion 15.40–17.30 Session 4. Approaches to treatment of patients with poor prognosis group Chairs: Tatiana Shamanskaya, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow Ilya Kazantsev, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St. Petersburg 15.40–15.55 Treatment of patients with primary resistant forms and recurrence of neuroblastoma. Experience of Raisa Gorbacheva Memorial Research Institute of Children Oncology, Hematology and Transplantation Ilya Kazantsev, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St. Petersburg 15.55–16.10 Is stage IV neuroblastoma treatable in children over 18 months? Marina Rubanskaya, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.10–16.25 High-dose polychemotherapy with auto-HSCT in the treatment of high risk patients with neuroblastoma. FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Anton Subora, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.25–16.40 Immunotherapy in neuroblastoma treatment in a poor prognosis group. FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Natalia Faseeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.40–16.55 Peculiarities of treating patients with neuroblastoma progression and recurrence Tatiana Shamanskaya, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 16.55–17.10 Experience of stereotactic irradiation in brain damaging neuroblastoma recurrence Mikhail Girshovich, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 17.10–17.30 Discussion

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09.00–14.00 «Live surgery» workshop session: oncourology Moderators: Sergey Petrov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Vagif Atduev, FBHI VDMC FMBA of Russia, Nizhny Novgorod Laparoscopic 3D radical cystectomy with ICG biopsy of signal lymph nodes, with intracorporeal orthotopic bladder formation

Venue: FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation» Surgical team: Alexander Nosov, Maria Berkut, Aleksey Novik

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Clinical research - science, international experience and investment in the medicine of future. 10.00–19.00 Section in the memory of Mikhail Lichinitser. (Not included in the CME program) 10.00–11.30 Session 1. Cochrane - an academic standard for clinical research Chairs: Andrey Kaprin, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Eevgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Andrey Mescheryakov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.00–10.05 Moderator: Artem Poltoratskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 10.05–10.25 Cochrane - an international organization of the evidence-based medicine gold standard Liliya Ziganshina, Evidence Based Medicine Center «Cochrane Russia», Kazan, Republic of Tatarstan 10.25–10.45 International cooperation in clinical research development: clinical trials registration, Cochrane partnership - WHO and Russian realities Ekaterina Yudina, Evidence Based Medicine Center «Cochrane Russia», Kazan, Republic of Tatarstan 10.45–11.05 Problems of incorporation Russian clinical studies results in Cochrane systematic reviews Elena Artamonova, Pavlov First St.Petersburg State Medical University, St. Petersburg 11.05–11.30 Discussion

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program) 14.00–16.05 Session 2. An ideal sponsor of a clinical trial VS an ideal clinical center Chairs: Yekaterina Dokukina, BIOCAD, St. Petersburg Dmitry Chagin, Association of Pharmaceutical Manufacturers of the Eurasian Economic Union, St. Petersburg Alexey Malikov, Almazov National Medical Research Centre, St. Petersburg Moderators: Artem Poltoratskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Kseina Teplova-Bareisha, Bayer, Moscow

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14.05–14.25 Criteria for an ideal clinical center selections as viewed by a Sponsor Alla Bloschinskaya, Novartis Pharma LLC, St. Petersburg 14.25–14.50 Selection of common interests Subject discussion 14.50–15.10 Roszdravnadzor recommendations for clinical trials performance in a study center Maria Vrubel, Roszdravnadzor agency for medical products state quality control organization, Moscow 15.10–15.35 Clinical Research Quality Issues Subject discussion 15.35–15.50 Top clinical studies trends and what it means for Russia Konstantin Gudkov, Astra Zeneca Russia, Moscow 15.50–16.05 Drivers of change in Russian clinical studies Subject discussion 16.05–16.20 Break 16.20–18.30 Session 3. Worldwide experience interchange Chairs: Igor Nikitin, «Treatment and rehabilitation center» of the Ministry of Health of Russia, Moscow Lyudmila Zhukova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Evgeny Rogov, Independent GCP/GLP-auditor, Moscow Sergey Simeniv, X7 Company, St. Petersburg 16.20–16.25 Moderator: Artem Poltoratskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.25–16.55 Global modernization of clinical studies after introduction of supplements to the High-quality Clinical Practice Guide 2017 Natalia Buchneva, UCB BioSciences GmbH, Düsseldorf, Germany 16.55–17.25 Clinical trials in Russia: External vision Vladimir Bogin, St. John Medical Center, Cromos Pharma, Batu Biologics, Portland, USA 17.25–17.40 Clinical trials - the territory of common interests Vladimir Andrianov, Institute of Interdisciplinary Medicine, Moscow

17.40–18.00 Clinical studies in the EEU - will anything change for doctors and patients? Dmitry Rozhdestvenskiy, Eurasian Economic Commission, Moscow 18.00–18.15 The tumor samples quality issues in oncological studies Yulia Nezametdinova, Astra Zeneca company, Moscow

18.15–18.30 Discussion

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09.00–18.40 Tumors of bones and soft tissues

09.00–11.30 Session 1. Soft tissue sarcomas Chairs: Georgy Gafton, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Aleksander Fedenko, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Mamed Aliev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.00–09.05 Opening 09.10–09.25 Role of a multidisciplinary team in diagnosis and treatment of bone and soft tissue tumors Grigory Zinoviev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 09.25–09.45 Current approach to soft tissue sarcomas chemotherapy Aleksander Fedenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.45–10.05 Soft tissue tumors: what`s new? Renato Covello, National Cancer Institute «Regina Elena» of Rome, Rome, Italy 10.05–10.25 Cryosurgery for soft tissue sarcoma interventions Mukhail Khanevich, Russian Hematology and Transfusion Medicine Research Institute, St. Petersburg 10.25–10.45 Reconstructive plastic surgeries for desmoid fibromas of body and extremities Anna Yadrina, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 10.45–11.00 Adjuvant treatment. Pros and cons Dilorom Latipova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.00–11.15 Perspective areas of soft tissue sarcomas radiotherapy Sergey Novikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 11.15–11.30 Discussion

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program)

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14.00–18.40 Session 2. Bone tumours Chairs: Valery Teplyakov, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Moscow Aleksander Zheravin, FSBI «E.N. Meshalkin National medical research center» of the Ministry of Healthcare of the Russian Federation, Novosibirsk Sergey Zaretskiy , N.N. Alexandrov National Cancer Centre of Belarus, Minsk, Republic of Belarus 14.00–14.15 Organisation of sarcoma treatment in Italy Francesco Nicolosi, Presidio Ospedaliero Garibaldi-Nesima, Catania, Italy 14.15–14.30 Giant cell bone tumours Dina Chuglova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.30–14.45 Peculiarities of surgical treatment of GCBT on the background of denosumab targeted therapy Anna Bogutdinova, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk 14.45–15.00 Strategy and tactics of onco-orthopedic supports for a flat bones lesion Valery Teplyakov, Moscow 15.00–15.15 Experience of reconstructive chest wall tumors surgeries Aleksander Zheravin, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Novosibirsk 15.15–15.30 Discussion 15.30–15.40 Break 15.40–15.55 Ewing sarcoma: what’s new in molecular aspects? Yong-Koo Park, Kyung Hee University Hospital, Seoul, South Korea 15.55–16.10 Errors in diagnosis and treatment of bones illustrated by clinical cases Aleksander Kurilchik, A. Tsyb Medical Radiological Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 16.10–16.25 Innovative technologies in treating patients with pelvic bone tumors Evgeny Sushentsov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.25–16.40 Hip arthroplasty in patients with proximal femur tumor lesions Ilkin Mikhailov, FSBI RSRI of TO n.a. R.R. Vreden under the Ministry of Health of Russia, St. Petersburg

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16.40–16.55 Complications of surgical treatment in pediatric patients with bone tumors Nikolai Bolshakov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow 16.55–17.05 Discussion 17.05–17.15 Break 17.15–17.30 Sacral bone chordoma. Histological variants of structure Surgical treatment Irina Bulycheva, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.30–17.45 Circular decompression of spinal chord in patients with metastatic thoracic spine lesions Aleksander Kasyuk, N.N. Alexandrov National Cancer Centre of Belarus, Minsk, Republic of Belarus 17.45–18.00 Endoprosthetics in onco-verbology Sergey Zaretskiy, N.N. Alexandrov National Cancer Centre of Belarus, Minsk, Republic of Belarus 18.00–18.15 Combined treatment of renal cell carcinoma bone metastases Anna Bogutdinova, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk 18.15–18.30 Discussion 18.30–18.40 Closing remarks

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The Fifth M. L. Gershanovich Conference «Head and Neck 09.00–11.25 tumours- Personalized Cancer Therapy: from science to practice» with interactive voting

09.00–11.20 Session 1. Evolution of drug therapy in the treatment of squamous cell head and neck cancer: innovations and breakthroughs! Chairs: Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Svetlana Kutukova, St. Petersburg City clinical oncology center, St. Petersburg Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Natalia Zhukova, St. Petersburg City clinical oncology center, St. Petersburg 09.00–09.05 Opening 09.05–09.25 Modern approaches to squamous cell head and neck cancer chemotherapy: the goal is to preserve not only an organ, but its function, too Natalia Zhukova, St. Petersburg City clinical oncology center, St. Petersburg 09.25–09.30 Discussion 09.30–09.55 Position of targeted therapy in squamous cell head and neck cancer treatment: yesterday, today, tomorrow Svetlana Kutukova, St. Petersburg City clinical oncology center, St. Petersburg 09.55–10.00 Discussion 10.00–10.15 Immunotherapy: a breakthrough in squamous cell head and neck cancer treatment Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg 10.15–10.20 Discussion 10.20–11.25 Session 2. Meeting of School of oncologists «A difficult case in oncology» Chairs: Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg Svetlana Kutukova, St. Petersburg City clinical oncology center, St. Petersburg Natalia Zhukova St. Petersburg City clinical oncology center, St. Petersburg 10.20–10.25 Opening

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10.25–10.40 Inefficacy of targeted and immunotherapy: what’s next? Svetlana Kutukova, St. Petersburg City clinical oncology center, St. Petersburg 10.40–10.45 Discussion 10.45–11.00 CUP syndrome: are there any prospects for treatment? Natalia Zhukova, St. Petersburg City clinical oncology center, St. Petersburg 11.00–11.05 Discussion 11.05–11.20 Radiation-resistant thyroid cancer: how can we help a patient today? Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg 11.20–11.25 Discussion

Official opening of the V St. Petersburg International 11.30–12.30 Oncological Forum «White Nights 2019» in the «Blue 4+5» hall

12.30–14.00 Sponsor symposium lunch** **(Not included in the CME program) 14.00–16.30 RUSSCO session Molecular imaging in oncology Chairs: Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Daniil Stroyakovskiy, SBHI Moscow city oncology hospital № 62 of the Moscow Healthcare Department, Moscow 14.00–14.25 From morphological diagnostics to molecular imaging Alexander Ivantsov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 14.25–14.30 Discussion 14.30–14.55 Immunohistochemical markers for treatment choice Grigoriy Raskin, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St. Petersburg 14.55–15.00 Discussion 15.00–15.25 Molecular markers for treatment choice Daniil Stroyakovskiy, SBHI Moscow city oncology hospital № 62 of the Moscow Healthcare Department, Moscow 15.25–15.30 Discussion 15.30–15.55 Hereditary tumor syndromes diagnosis Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 15.55–16.00 Discussion

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16.00–16.25 Prospects for molecular imaging in oncology Yevgeniy Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.25–16.30 Discussion 16.40–18.40 The Fifth M. L. Gershanovich Conference «Non-small cells lung cancer - Personalized Cancer Therapy: from science to practice» with interactive voting

16.40–18.40 Recent achievements in non-small cells lung cancer systemic treatment Expert panel: Vladimir Moiseenko, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St. Petersburg Gilberto de Lima Lopes Junior, «Sylvester Comprehensive Cancer Center at the University of Miami and the Miller School of Medicine», Miami, USA Sergey Orlov, FSBSI Research Institute of Medical Primatology, St. Petersburg Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 16.40–16.45 Introductory word Vladimir Moiseenko, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St. Petersburg 16.45–17.05 The best materials of conferences of 2019 in systemic treatment of non- small cells lung cancer Gilberto de Lima Lopes Junior, «Sylvester Comprehensive Cancer Center at the University of Miami and the Miller School of Medicine», Miami, USA

17.05–17.25 Latest achievements in non-small cells lung cancer immunotherapy Vladimir Moiseenko, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St. Petersburg 17.25–17.35 Clinical experience of immunotherapy in the Russian Federation Mikhail Kramchaninov, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St. Petersburg 17.35–17.40 Interactive voting and discussion 17.40–18.00 Recent achievements in targeted therapy of non-small cells lung cancer with activating mutations (Sponsored by a company*. Not included in the program for NMOs) Sergey Orlov, FSBSI Research Institute of Medical Primatology, St. Petersburg 18.00–18.10 Clinical experience of targeted therapy in the Russian Federation Elena Karabina, Tula Cancer Center, Tula 18.10–18.15 Interactive voting and discussion 18.15–18.25 Clinical experience of combined treatment of non-small cells lung cancer in the Russian Federation Nikolai Vorobiev, Treatment and diagnostic center of Medical Institute named after Berezin Sergey, St. Petersburg 18.25–18.30 Interactive voting and discussion 18.30–18.40 Closing remarks

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JUNE, 22, SATURDAY

09.00–17.00 Conference on palliative care for cancer patients Diana Nevzorova, SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow Guzel Abuzarova, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Alla Ryazankina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Elena Polevichenko, FSBEI Pirogov Russian National Research Medical University under the MoH of Russia, Moscow 09.00–09.25 Palliative medical care for cancer patients Diana Nevzorova, SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow 09.25–09.30 Discussion 09.30–09.55 Ways of interaction between adult and children departments of pediatric palliative care services Elena Polevichenko, FSBEI Pirogov Russian National Research Medical University under the MoH of Russia, Moscow 09.55–10.00 Discussion 10.00–10.30 Palliative care integration in work FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Alla Ryazankina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.30–10.35 Discussion 10.35–10.55 On opioid analgesics pharmacology Alexander Sidorov, FSBEI Yaroslavl State Medical University, Yaroslavl 10.55–11.00 Discussion 11.00–11.20 Safe use of opioids in cancer patients Guzel Abuzarova ,P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 11.20–11.25 Discussion 11.25–11.50 Management of intensive pain in children under palliative care Gleb Ulrikh, FSBEI HE Saint-Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation, St.Petersburg

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11.50–12.00 Discussion 12.00–12.25 Nutritional support for cancer patients in need of palliative care Valeriy Luft, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine, St.Petersburg 12.25–12.30 Discussion 12.30–12.55 Interaction with relatives of a seriously ill patient. Conflict resolution Elena Shimanskaya, St. Petersburg State Budgetary Healthcare Institution «Hospitage № 1», St.Petersburg 12.55–13.00 Discussion 13.00–13.30 Break 13.30–15.00 «Sponsor symposium lunch** **(Not included in the CME program)» 15.00–17.00 Panel meeting of the Ministry of Healthcare of the Russian Federation specializing in palliative medical care

Chairs: Diana Nevzorova, SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow Elena Polevichenko, FSBEI Pirogov Russian National Research Medical University of the Ministry of Healthcare of the Russian Federation, Moscow 15.00–16.30 Panel meeting 16.30–17.00 Discussion

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Circulating nano-vesicles: their role in oncological diseases 08.30–12.30 pathogenesis and prospects for application in oncology practice Chairs: Anastasia Malek, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Dmitry Gorin, Skolkovo Institute of Science and Technology, Moscow Svetlana Tamkovich, Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences, Novosibirsk 08.30–08.45 Exosomal miRNA in the regulation of tumor cells hormonal sensitivity Mikhail Krasilnikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.45–09.00 Exosome proteins associated with blood cells as a new source of biomaterial for non-invasive diagnosis of breast cancer» Oleg Tutanov, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 09.00–09.05 Discussion 09.05–09.20 Metalloproteinases of exosomes in colorectal cancer: association with metabolic disorders Anastasia Dimcha, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk 09.20–09.25 Discussion 09.25–09.40 Influence of cerebrospinal fluid exosomeson proliferative and migratory activity of malignant gliomas cells Tatiana Shtam, Petersburg Nuclear Physics Institute named by B.P.Konstantinov of NRC «Kurchatov Institute», St.Petersburg 09.40–09.45 Discussion 09.45–10.00 Exosomes associated with the blood elements of cancer patients stimulate angiogenesis in the in vitro system Svetlana Tamkovich, Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences, Novosibirsk 10.00–10.05 Discussion 10.05–10.20 Biodistribution of exosomes in various types of administration in vivo in mice Nikolay Verlov, Petersburg Nuclear Physics Institute named by B.P.Konstantinov of NRC «Kurchatov Institute», St.Petersburg 10.20–10.25 Discussion 10.25–10.40 Extracellular nano-vesicle extractions: basic technologies and new trends Pavel Laktionov, Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences, Novosibirsk

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10.40–10.45 Discussion 10.45–11.00 Isolation of specific exosomes populations using aptamers Nadezhda Nikiforova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.00–11.05 Discussion 11.05–11.20 New methods of photonics for exosomes visualization and detection Dmitry Gorin, Skolkovo Institute of Science and Technology, Moscow 11.20–11.25 Discussion 11.25–11.40 Visualization of single nanoparticles using light sheet microscopy Yuri Vainer, Institute for Spectroscopy RAS, Moscow 11.40–11.45 Discussion 11.45–12.00 Opportunities and prospects of microfluidics for membrane nano- vesicles analysis Vasily Chernyshev, Skolkovo Institute of Science and Technology, Moscow 12.00–12.05 Discussion 12.05–12.20 Method of giant Raman scattering for exosomes detection and analysis Aleksey Yashenyuk, Skolkovo Institute of Science and Technology, Moscow 12.20–12.30 Discussion 12.30–14.00 Break 14.00–18.00 Current issues of anesthesiology and intensive care

Chairs: Yury Polushin, Pavlov First Saint Petersburg State Medical University, St.Petersburg Fidel Bayshev, Portsmouth Hospitals NHS trust Southwick Hill road Portsmouth, Portsmouth, UK Vladimir Glushchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Sergey Rozengard, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.00–14.30 Anesthesia and Infection risk Fidel Bayshev, Portsmouth Hospitals NHS trust Southwick Hill road Portsmouth, Portsmouth, UK

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14.30–14.50 Current view on the functional operability problem in lung reduction Mikhail Kovalev, Pavlov First Saint Petersburg State Medical University, St.Petersburg 14.50–15.05 ALV mode selection for laparoscopic onco-gynecological operations in patients with obesity Sergey Rozengard, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.05–15.20 Practice of dexmedetomidine use in cancer patients Mikhail Gurin, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.20–15.35 Discussion 15.35–15.45 Break 15.45–16.00 Levobupivacaine and ropivacaine compared in transurethral resection of bladder under spinal anesthesia in elderly patients Kirill Tsygankov, S.M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation, St.Petersburg 16.00–16.10 Presentation of a clinical case with single-lung ventilation in a patient with skull front part deformation Ksenia Golubeva FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.10–16.25 Practice of extracorporeal detoxification methods use in an oncological hospital intensive care unit Dmitry Morikov, SBHI «Regional cancer center», Irkutsk 16.25–16.40 Extracorporeal detoxification in intensive care for acute renal damage in patients with cervical cancer Victoria Mikhailova, SBHI «Regional cancer center», Irkutsk 16.40–16.50 Discussion 16.50–17.00 Break 17.00–17.15 Prevalence of resistant pathogens in surgical oncological patients at a hospital (local data): Problems and lines of approach Anna Seliuta, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.15–17.30 Clinical and neurological features of hospital-acquired stroke in patients with oncology Vladislav Andreev, Pavlov First Saint Petersburg State Medical University, St.Petersburg 17.30–17.45 Rehabilitation in anesthesiology, reanimation and intensive treatment department When to start and how to control efficacy? Irina Ruslyakova, North-western State Medical University named after I.I. Mechnikov, St. Petersburg 17.45–18.00 Discussion

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08.30–12.30 «Discussion in cervical cancer treatment State-of-the-art Clinical case studies» 08.30–09.00 Key-note lecture: «The problem of cervical cancer: key-note stages» Lev Ashrafyan, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.00–10.05 Cervical cancer IB2 Chairs: Elena Novikova, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Elena Bakhidze, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.00–09.10 Clinical case presentation Konstantin Guseynov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–09.25 Radiologist’s opinion Chemoradiotherapy Lyudmila Krikunova, A. Tsyb Medical Radiological Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 09.25–09.40 Surgeon’s opinion: Combined treatment Olga Smirnova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.40–09.55 Surgeon’s opinion: Primary debulking Valentina Nechushkina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation St.Petersburg 09.55–10.05 Discussion 10.05–11.10 Cervical cancer REC Chairs: Svetlana Khokhlova, FBSI «V.I. Kulakov Science center for obstetrics, gynecology and perinatology» of the Ministry of Healthcare of the Russian Federation, Moscow Svetlana Mukhtarulina, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Kirill Zhordaniya, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.05–10.15 Clinical case presentation Yuriy Trifanov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.15–10.30 Radiologist’s opinion Lyudmila Krikunova, A. Tsyb Medical Radiological Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 10.30–10.45 Surgeon’s opinion Kirill Shostka, SBHI oncology center for Leningrad region, St.Petersburg 10.45–11.00 Chemotherapist’s opinion Aleksandra Tyulyandina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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11.00–11.10 Discussion 11.10–12.15 Cervical cancer and pregnancy Chairs: Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Sergey Krasilnikov, SBHI of the Novosibirsk Region «Novosibirsk Regional Oncologic Center», Novosibirsk 11.10–11.20 Clinical case presentation Khristina Kotiv, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.20–11.35 Surgeon’s opinion Igor Berlev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.35–11.50 Chemotherapist’s opinion Svetlana Hohlova, «FBSI «V.I. Kulakov Science center for obstetrics, gynecology and perinatology» of the Ministry of Healthcare of the Russian Federation», Moscow 11.50–12.05 Reproductive outcomes after cervical cancer treatment Anna Sidoruk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.05–12.15 Discussion 12.15–12.30 Conclusion 12.30–14.00 Sponsor symposium lunch** ** (Not included in the CME program) 14.00–16.00 Prevention and risk management in an oncology clinic. How to protect yourself and a clinic Chairs: Yulia Pavlova, National Institute of Medical Law, Moscow Yulia Meshcheryakova, Scientific Medical Society «Medical Practice», Moscow 14.00–14.10 Opening 14.10–14.40 Recommendation of the federal patient care center: an opportunity or a threat? Yulia Pavlova, National Institute of Medical Law, Moscow 14.40–15.10 What is more important: documents or a patient? Yulia Pavlova, National Institute of Medical Law, Moscow 15.10–15.40 A doctor and investigative actions: what to do? Nail Idrisov, Saint Petersburg Academy of the Investigative Committee of the Russian Federation, St.Petersburg 15.40–16.00 Discussion

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09.00–12.30 Debatable issues of colorectal cancer

09.00–10.00 Session 1. T1-T2 rectal cancer: Neoadjuvant treatment, expectant management and total mesorectal excision Chair: Yury Shelygin, FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow Moderators: Alexey Karachun, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Evgeny Rybakov, FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow Marina Chernykh, PET Technology Podolsk ,Podolsk 09.00–09.20 Neoadjuvant treatment and expectant management Geerard Beets, Maastricht University, Amsterdam, Netherlands 09.20–09.40 Total mesorectal excision Pawel Mrochkovski, Otto-von-Guericke Universität Magdeburg, Kassel, Germany 09.40–10.00 Case study analysis and discussion 10.15–11.15 Session 2. Transanal endoscopic microsurgery and endoscopic submucosal dissectionransanal Chair: Yury Shelygin , FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow Moderators: Sergey Vasiliev, St. Petersburg scientific and practical center for coloproctology, St.Petersburg Evgeny Fedorov, State clinical hospital № 31 , Moscow Igor Pravosudov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.15–10.35 Transanal endomicrosurgery Evgeny Rybakov, FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow 10.35–10.55 Endoscopic submucosal dissection Oleg Tkachenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.55–11.15 Case study analysis and discussion

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11.30–12.30 Session 3. Chemotherapy and surgery for colorectal cancer with peritoneal carcinomatosis Chair: Yury Shelygin, FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow Moderators: Sergey Achkasov, FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow Andrey Domansky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Gulfiya Teletaeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.30–11.50 Surgery Oleg Sushkov, FSBI «State scientific coloproctology center named after A.N. Ryzhikh» of the Ministry of Health of Russia, Moscow 11.50–12.10 Chemotherapy Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.10–12.30 Discussion 12.30–14.00 Break

Meeting of the European Society of Surgical Oncology (ESSO) 14.00–16.50 during the White Nights Forum 2019

14.00–14.45 Lecture of the President of the European Society of Surgical Oncology (ESSO) Chairs: Domenico D’Ugo, Catholic University of Rome, Rome, Italy Aisha Isaeva, Moscow Oncology Research Institute n.a. P.Hertsen, Moscow Nikita Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.00–14.30 New approaches to mesocolic excision and total mesorectal excision Domenico D’Ugo, Catholic University of Rome, Rome, Italy 14.30–14.45 Discussion 14.50–16.50 Joint session of young surgeons with the European Society of Surgical Oncology (ESSO) Chairs: Domenico D’Ugo, Catholic University of Rome, Rome, Italy Aisha Isaeva, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Nikita Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg

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14.50–15.05 What divides an oncologist from a general surgeon? Domenico D’Ugo, Catholic University of Rome, Rome, Italy 15.05–15.20 How did I become an oncologist? Andreas Brandl, Champalimaud Centre for the Unknown Av. De Brasília, Doca de Pedrouços, Lisbon, Portugal 15.20–15.45 Expectations/realia of a young oncology surgeon Aisha Isaeva, P.A. Hertsen Moscow Oncology Research Center - branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 15.45–16.00 Practical advice to young surgeons moving to manual skills improvement Nikita Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.00–16.15 Clinical research in surgery: from idea to implementation Aleksey Petrov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.15–16.30 ESSO opportunities on the way to a career success Andreas Brandl, Champalimaud Centre for the Unknown Av. De Brasília, Doca de Pedrouços, Lisbon, Portugal 16.30–16.50 Discussion

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09.00–18.40 Fundamental aspects of cancer immunology

09.00–11.10 Session 1. Fundamental issues of cancer immunology Chairs: Irina Baldueva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Zaira Kadagidze, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.00–09.10 Opening 09.10–09.25 Problems of personalized immune therapy with immunity checkpoints inhibitors: PD-1/PD-L1 Zaira Kadagidze, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.25–09.30 Discussion 09.30–09.45 Non-viral gene surgery of recombinant T-cells in vivo Vitaly Alexeev , Thomas Jefferson University, Philadelphia, USA 09.45–09.50 Discussion 09.50–10.05 Tumor growth cytokine regulation Andrey Simbirtsev, FSUE State Research Institute of high pure biopreparations under Federal medical-biological agency, St.Petersburg 10.05–10.10 Discussion 10.10–10.25 Tumor-associated macrophages and chitinase like proteins: prospects for tumor therapy Julia Kzyshkovska, Tomsk state university, Institute for trasfusion medicine and immunology Mannheim Faculty of Medicine, Tomsk 10.25–10.30 Discussion 10.30–10.45 Paraneoplastic disease as a tumor progression manifestation: systemic phenomena and mechanisms Viktor Kozlov, FSBSI «Institute of Toxicology» of the Federal Medical- Biological Agency, St.Petersburg 10.45–10.50 Discussion 10.50–11.05 Tumor stem cells in tumors growth and metastasis at various localization Alexander Sagakyants, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don 11.05–11.10 Discussion

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11.10–16.40 Session 2. Domestic research in cancer immunology Chairs: Viktor Kozlov, FSBSI «Institute of Toxicology» of the Federal Medical- Biological Agency, St.Petersburg Petr Nazarov, FSBSI «Institute of experimental medicine» of the North-West Branch of the Russian Academy of Medical Sciences, St.Petersburg Andrey Simbirtsev, FSUE State Research Institute of high pure biopreparations under Federal medical-biological agency, St.Petersburg 11.10–11.25 New therapy opportunities for PRAME-expressing cancer Vsevolod Misyurin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 11.25–11.30 Discussion 11.30–11.45 Prognostic role of immunosuppressive factors production by tumor cells in assessing the gene therapy efficacy for disseminated solid tumors Anna Danilova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.45–11.50 Discussion 11.50–12.05 Factors of monocyte involvement in breast cancer pathogenesis Marina Staheeva, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk 12.05–12.10 Discussion 12.10–12.25 Genetically modified lymphocytes with chimeric T-cell receptor for the solid tumors treatment Mikhail Kiselevsky, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.25–12.30 Discussion 12.30–14.00 Sponsor symposium lunch** ** (Not included in the CME program) 14.00–14.15 Topical diagnosis of immune disorders with flow cytometry in oncology Alexander Borisov, Federal Research Center «Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences», Krasnoyarsk 14.15–14.20 Discussion 14.20–14.35 Systemic and local immunity in cancer patients Tatiana Zabvotina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.35–14.40 Discussion

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14.40–14.55 Clinical and immunological aspects of disseminated melanoma anti- CTLA-4 treatment Ekaterina Anokhina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.55–15.00 Discussion 15.00–15.15 Regulatory mechanisms of phenotype formation and of dendritic cells functional activity Andrey Savchenko, Federal Research Center «Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences», Krasnoyarsk 15.15–15.20 Discussion 15.20–15.35 Peripheral blood T-helper subpopulation changes in skin melanoma Igor Kudryavtsev,FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.35–15.40 Discussion 15.40–15.45 Chronic inflammation and cancer: Myeloid suppressor cells as the most important link Nikolay Belyaev, FSSI Saint-Petersburg Pasteur Institute, St.Petersburg 15.45–16.00 Discussion 16.00–16.15 Role of plasmapheresis and non-specific immunotherapy in comprehensive treatment of patients with locally advanced cervical cancer Anna Menshenina, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don 16.15–16.40 Discussion 16.40–18.20 Session 3. Perspective trends in the development of cancer immunology. Immunotherapy in pediatric oncology Chairs: Nadezhda Cherdyntseva, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk Svetlana Kuleva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Aleksander Druy, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 16.40–16.45 Genomic instability of a tumor as a predictor of immunotherapy efficacy Aleksander Druy, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 16.45–17.00 Discussion

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17.00–17.15 Production of autologous biomedical cell products using automated closed systems – Quantum Cell Expansion System and CliniMACS Prodigy Vladislav Sergeev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.15–17.20 Discussion 17.20–17.35 Immuno-targeting hepatic metastasis Takami Sato, Thomas Jefferson University, Philadelphia, USA 17.35–17.40 Discussion 17.40–17.55 Immune system modulation ways in pediatric oncology: practice of FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Svetlana Kuleva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.55–18.00 Discussion 18.00–18.15 Review of immune pathogenetic mechanisms of adverse events during treatment with checkpoints inhibitors Irina Baldueva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 18.15–18.20 Discussion 18.20–18.40 Theses review Aleksey Novik, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg

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08.00–18.00 Organization of medical care for children with oncological diseases 08.00–12.00 Session 1. Organization of medical care for children with oncological diseases Chairs: Maxim Rykov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Ivan Turabov, FSBEI «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk Svetlana Kuleva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Olga Manerova, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow 08.00–08.30 Medical care for children with cancer diseases in the Russian Federation: main indicators, trends, development strategy Maxim Rykov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.30–08.45 Main trends of pediatric morbidity and mortality due to malignant diseases in the North-West Federal District Ivan Turabov, FSBEI «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk 08.45–09.00 Medical care for children with cancer in Arkhangelsk region Ivan Turabov, FSBEI «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk 09.00–09.15 The role of pediatric oncology department of the third B level medical organization in the organization of medical care for children in a federal district Svetlana Kuleva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.15–09.30 Organization of oncological care for children in a regional multi- disciplinary pediatric hospital Andrey Karmanov, Republican children’s clinical hospital, Syktyvkar 09.30–09.45 Informatization in pediatric oncology Maxim Rykov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.45–10.00 Discussion 10.00–10.30 Break

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10.30–11.00 Clinical Management essentials Olga Manerova, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow 11.00–11.45 What is management and who are the managers? Maxim Rykov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 11.45–12.00 Discussion 12.00–14.30 Break 14.30–18.00 Session 2. Some aspects of treating patients with hemoblastosis and solid tumors Chairs: Maxim Rykov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Ivan Turabov, FSBEI «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk Olga Zheludkova, FSBI «Russian Scientific Center of radiology and nuclear medicine» of the Ministry of Health of Russia, Moscow 14.30–14.45 Prognostic value of clinical, morphological and molecular characteristics of medulloblastoma in children undergoing multicenter treatment under the HIT protocol Olga Zheludkova, FSBI «Russian Scientific Center of radiology and nuclear medicine» of the Ministry of Health of Russia, Moscow 14.45–15.00 Results of 72 ATRT patients treatment Lyudmila Olhova, FSBI «Russian Scientific Center of radiology and nuclear medicine» of the Ministry of Health of Russia, Moscow 15.00–15.15 A patient with a brain tumor: a clinical case Valeria Bondarenko, FSBI «Russian Scientific Center of radiology and nuclear medicine» of the Ministry of Health of Russia, Moscow 15.15–15.30 Differentiated therapy for patients with a diffuse brain stem tumor Olga Regentova, FSBI «Russian Scientific Center of radiology and nuclear medicine» of the Ministry of Health of Russia, Moscow 15.30–14.45 Endocrine disorders in patients with CNS tumors post-treatment: correction possibilities Nadezhda Mazerkina, FSAI N. N. Burdenko Institute of Neurosurgery of the ministry of Health of Russia, Moscow 15.45–16.00 Discussion 16.00–16.15 Break 16.15–16.30 Acute child leukemia in the Arkhangelsk region Anna Ulanova, P.G. Vyzhletsov Arkhangelsk Regional Pediatric Clinical Hospital, Arkhangelsk

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16.30–16.45 Nivolumab in the treatment of children with Hodgkin’s lymphoma Andrey Kozlov, Pavlov First Saint Petersburg State Medical University, St.Petersburg 16.45–17.00 Efficacy of tandem high-dose polychemotherapy with auto-HSCT in treatment of children with embryonic CNS tumors Hasmik Gevorgyan, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg 17.00–17.15 Efficacy of high-dose polychemotherapy with auto-HSCT in treatment of children with tumors of the Ewing sarcoma family Tatiana Yukhta, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg 17.15–17.30 Organization of transfusiology support for patients in the bone marrow transplantation clinic: features of a transplant preparation and substitution transfusion in pediatric patients Polina Kuga, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg 17.30–17.45 Features of nutrition and nutritional support in children under chemoradiation therapy and HSCT Maksim Kucher, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg 17.45–18.00 Discussion

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Roundtable discussion. Multidisciplinary discussion of microbiome 08.45–12.30 role in oncology «Microcosm in a body’s macrocosmos» 08.45–10.20 Session 1. Multidisciplinary discussion of the microbiome role in oncology Expert panel: Elena Ilina, FSBEI Federal Research And Clinical Center of Physical- Chemical MedicineFederal Medical Biological Agency of Russia, Moscow Maria Ardatskaya, FSBI CPE «Central State Medical Academy», Moscow Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Elena Poluektova, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.45–08.55 Opinion of a clinical oncologist. Multidisciplinary approach to malignant tumors prevention and treatment Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.55–09.00 Discussion 09.00–09.10 Opinion of a molecular geneticist. Microorganisms and cancer Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–09.15 Discussion 09.15–09.30 Intestinal microbiota action in human health Elena Ilina, FSBEI Federal Research And Clinical Center of Physical- Chemical MedicineFederal Medical Biological Agency of Russia, Moscow 09.30–09.35 Discussion 09.35–09.45 A body microbiom from a microbiologist’s viewpoint Viktor Tets, Pavlov First St.Petersburg State Medical University, St.Petersburg 09.45–09.50 Discussion 09.50–10.00 Opinion of a gastroenterologist. GI microbiota – priority study areas Elena Poluektova, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow 10.00–10.05 Discussion 10.05–10.15 Opinion of a gastroenterologist. Metabolomics of intestinal metabolites – a mechanism to realize negative effects of microbiome damage Maria Ardatskaya, FSBI CPE «Central State Medical Academy», Moscow 10.15–10.20 Discussion

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10.20–10.25 Break 10.25–12.30 Section 2. Multidisciplinary discussion of the microbiome role in oncology Expert panel: Elena Ilina, FSBEI Federal Research And Clinical Center of Physical- Chemical MedicineFederal Medical Biological Agency of Russia, Moscow Alexander Zakharchenko, Pavlov First St.Petersburg State Medical University St.Petersburg Tatiana Kalanchnyuk , FSBEI Federal Research And Clinical Center of Physical-Chemical MedicineFederal Medical Biological Agency of Russia, Moscow Evgeny Olekhnovich, FSBEI Federal Research And Clinical Center of Physical-Chemical MedicineFederal Medical Biological Agency of Russia, Moscow Roman Ivanov, Biocad, St.Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Igor Stoma, EI Belarusian State Medical University, Minsk, Republic of Belarus Oleg Goloshchapov, Raisa Gorbacheva Memorial Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg Alexander Suvorov, FSBSI «Institute of experimental medicine», St. Petersburg 10.25–10.40 Opinion of a molecular biologist. Mechanisms of human microbiota recovery in dysbiosis. Probiotics Alexander Suvorov, FSBSI «Institute of experimental medicine», St.Petersburg 10.40–10.45 Discussion 10.45–10.55 Opinion of an infectious disease physician. Composition of intestinal microbiota as a predictor of outcomes in oncohematology patients Igor Stoma, EI Belarusian State Medical University, Minsk, Republic of Belarus 10.55–11.00 Discussion 11.00–11.15 Opinion of a resuscitator. Fecal microbiota transplantation in patients following hematopoietic stem cell transplantation. Fecal microbiota transplantation results in 2015–2019 Oleg Goloshchapov, Raisa Gorbacheva Memorial Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg 11.15–11.20 Discussion 11.20–11.30 Opinion of an oncology coloproctologist. Perioperative changes in intestinal microbiocenosis in colorectal cancer patients Alexander Zakharenko, Pavlov First St.Petersburg State Medical University, St.Petersburg 11.30–11.35 Discussion

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11.35–11.45 Opinion of a gastroenterologist. Therapeutic effect following fecal microbiota transplantation Tatiana Kalanchnyuk, FSBEI Federal Research And Clinical Center of Physical-Chemical MedicineFederal Medical Biological Agency of Russia, Moscow 11.45–11.50 Discussion 11.50–12.00 Analytical models after fecal microbiota transplantation Evgeny Olekhnovich, FSBEI Federal Research And Clinical Center of Physical-Chemical MedicineFederal Medical Biological Agency of Russia, Moscow 12.00–12.05 Discussion 12.05–12.20 Intestinal microbiome: diagnostic and therapeutic potential in immuno- oncology Roman Ivanov, Biocad, St.Petersburg 12.20–12.25 Discussion 12.25–12.30 Discussion. Prospects of further study of the microbiome in oncology 12.30–14.00 Break 14.00–18.45 Conference «Automated Information Systems in Medicine 2019» 14.00–15.25 Session 1. International experience in healthcare digital transformation Chairs: Elena Boyko, Ministry of Health of the Russian Federation, Moscow Artem Panin, Federal service on supervision in sphere of public health services, Moscow Leonid Konstantinov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Moderator: Artem Poltoratskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.00–14.10 Opening 14.10–14.25 How to implement the prospects of e-healthcare in a changing world. Way of Hirv Piret, Science Park Tehnopol, Tallinn, Estonia 14.25–14.40 Digital medicine in Estonia. Advantages of a small country Sergey Saadi, Minudoc.ee medical video consultation platform, Tallinn, Estonia 14.40–14.55 Possibility of digital technology use in medicine Gayane Arutyunyan, IBM, Moscow

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14.55–15.10 Digital transformation and artificial intelligence in healthcare. Trends, strategies, technologies and examples of use Alexander Khudyakov, Microsoft, St.Petersburg 15.10–15.25 Discussion 15.25–15.40 Break 15.40–17.05 Session 2. Russian experience in healthcare digital transformation Chairs: Irina Ganus, Committee for science and higher school of administration of Saint-Petersburg, St.Petersburg Alexander Shcherbakov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.40–15.50 Requirements of Roszdravnadzor to medical information systems (MIS) Artem Panin, Federal service on supervision in sphere of public health services, Moscow 15.50–16.00 Development of preventive medicine using artificial intelligence Alexander Gusev, National medical knowledge base, Petrozavodsk 16.00–16.05 Discussion 16.05–16.15 Strategy of medical artificial intelligence in Russia and the first examples of implementation Sergey Morozov, SBHI Scientific and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Healthcare Department of the City of Moscow, Moscow 16.15–16.20 Discussion 16.20–16.30 Practical experience in implementing cancer diseases screening projects using artificial intelligence technologies Sergey Sorokin, Botkin.ai, Moscow 16.30–16.35 Discussion 16.35–16.45 Advanced efficiency medicine of – convergence of the human and artificial intelligence Alexander Oksanenko, Skychain Global Moscow 16.45–16.50 Discussion 16.50–17.00 Neural networks use in the medicine of the future Alexey Dobrusin, Start-up center of Samara state medical university, Samara

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17.00–17.05 Discussion 17.05–17.20 Break 17.20–18.45 Session 3. Applied solutions for digital oncology Chairs: Georgiy Lebedev, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, St.Petersburg Irina Kargalskaya, Onconet platform, Moscow Kirill Vasilyev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.20–17.30 Telemedicine and capabilities of remote monitoring of cancer patients at different stages of diagnosis, treatment and rehabilitation Boris Zingerman, «TelePat» LLC, Kazan, Republic of Tatarstan 17.30–17.35 Discussion 17.35–17.45 Integration of full cycle of television technologies in the oncological service work of Lipetsk region: from teleconsultation and tele-education to remote monitoring and rehabilitation of cancer patients Sergey Shinkarev, SHI «Lipetsk regional cancer center», Lipetsk 17.45–17.50 Discussion 17.50–18.00 Telemedicine in modern healthcare Alexey Karpinsky, iCore, Moscow 18.00–18.05 Discussion 18.05–18.15 Possibilities of using telemedicine technologies in surgery Vladimir Krivenko, Medical Visual Systems, St.Petersburg 18.15–18.20 Discussion 18.20–18.30 Full cycle automated histological service system Oleg Nikitin, «CMO» LLC, Moscow 18.30–18.35 Discussion 18.35–18.45 Сlosing remarks

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09.00–12.00 Training course on radical prostatectomy Chairs: Sergey Petrov , Pavlov First St.Petersburg State Medical University, St.Petersburg Evgeny Veliev, S.P. Botkin Clinical infectious diseases hospital, Moscow Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.00–09.05 Opening 09.05–09.25 Anatomy and physiology of pelvis Sergey Reva, Pavlov First St.Petersburg State Medical University, St.Petersburg 09.25–09.30 Discussion 09.30–09.50 History of prostate cancer surgical treatment development Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.50–10.00 Discussion 10.00–10.25 Provision of functional results when performing radical prostatectomy. Part 1. Urine continence Evgeny Valiev, S.P. Botkin Clinical infectious diseases hospital, Moscow 10.25–10.30 Discussion 10.30–10.55 Technical features of radical prostatectomy Sergey Petrov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.55–11.00 Discussion 11.00–11.25 Provision of functional results when performing radical prostatectomy. Part 2. Sexual function Evgeny Veliev, S.P. Botkin Clinical infectious diseases hospital, Moscow 11.25–11.30 Discussion 11.30–11.50 Possible complications during radical prostatectomy and their correction Renat Guspanov, 1st City Hospital named after N.I. Pirogov, Moscow 11.50–11.55 Discussion 11.55–12.00 Closing 12.00–14.00 Break

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14.00–15.15 Applied bioethics in medical communication and journalism * (Not included in the CME program)

Moderator: Dmitry Malkov , «Saint-Petersburg National Research University Information Technologies, Mechanics and Optics», St.Petersburg 14.00–14.20 Applied bioethics: how to assess the social impact of new biomedical developments and medicinal products Daniela Ovadia, Agency Zoe, Milan, Italy 14.20–14.40 Translation problems: science and pharmaceutical business, country features and valuable precious life Anton Gopka, «Saint-Petersburg National Research University Information Technologies, Mechanics and Optics», St.Petersburg 14.40–15.00 The problem of assessing medical expert level of speakers in media and Internet communications Ilya Fomintsev, Cancer Prevention Foundation, St.Petersburg 15.00–15.15 Discussion

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08.50–19.20 Head and neck tumors

08.50–11.15 Session 1. Thyroid cancer and parathyroid glands cancer Chairs: Evgeny Choynzonov, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk Igor Reshetov, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow Sergey Podvyaznikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.50–09.00 Opening 09.00–09.10 Thyroid cancer. Evolution of treatment. Modern vision of the treatment problem Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–09.15 Discussion 09.15–09.30 Preparation for treatment with radioactive iodine of patients with highly differentiated thyroid cancer Pavel Rumyantsev, FSBI «National Medical Research Center of Endocrinology», Moscow 09.30–09.35 Discussion 09.35–09.50 Clinical indications for radioiodine therapy. 5 years experience of FSBHI N.A. Semashko Northern Medical Clinical Center of Federal Bio-Medical Agency of Russia Larisa Arapova, FSBHI N.A. Semashko Northern Medical Clinical Center of Federal Bio-Medical Agency of Russia, Arkhangelsk 09.50–09.55 Discussion 09.55–10.10 Modern capabilities of medicinal treatment of radioiodine refractory differentiated thyroid cancer Sergey Podvyaznikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.10–10.15 Discussion 10.15–10.30 Repeated surgery in patients with differentiated thyroid cancer Artem Garev, SBHI «Chelyabinsk regional clinical center for oncology and nuclear medicine», Chelyabinsk 10.30–10.35 Discussion

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10.35–10.50 Drug treatment of medullary thyroid cancer Ilya Romanov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.50–10.55 Discussion 10.55–11.10 Practice of diagnosis and treatment of parathyroid gands cancer in the Republic of Tatarstan Zinaida Afanasyeva, SAHI Republican clinical cancer center of Ministry of health of the Republic of Tatarstan, Kazan, Republic of Tatarstan 11.10–11.15 Discussion 11.15-12.30 Break 12.30–14.00 Sponsor symposium lunch** **( Not included in the CME program) 14.00–16.00 Session 2. Innovative technologies in head and neck tumors combined treatment Chairs: Ali Mudunov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Roberto Puxeddu, University of Cagliari, Cagliari, Italy Paul-Stefan Mauz, University of Tubingen, Tubingen, Germany Andrey Polyakov, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 14.00–14.15 Transoral Laser Microsurgery of Laryngeal and Pharyngeal Cancer vs Primary Radiation Paul-Stefan Mauz, University of Tubingen, Tubingen, Germany 14.15–14.20 Discussion 14.20–14.35 CO2 laser resections of oropharyngeal pharyngeal tumors Roberto Puxeddu, University of Cagliari, Cagliari, Italy 14.35–14.40 Discussion 14.40–14.55 Resections of Tumors of the Midface and Paranasal Sinus and Reconstruction with Resorbable Polylactide Paul-Stefan Mauz, University of Tubingen, Tubingen, Germany 14.55–15.00 Discussion 15.00–15.15 Reparative plastic surgery of the maxillofacilal area in cancer patients Evgeny Choynzonov, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk 15.15–15.20 Discussion 15.20–15.35 Reparative surgery in patients after upper and lower jaws resection Andrey Polyakov, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia , Moscow

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15.35–15.40 Discussion 15.40–15.55 Microsurgical reconstruction of oral cavity tissues in cancer patients Alexander Boyko, SBHI oncology center for Leningrad region, St.Petersburg 15.55–16.00 Discussion 16.00–16.10 Break 16.10–18.10 Session 3. Salivary glands tumours. Diagnosis and treatment Chairs: Khurshid Khrwatany, Hawler Medical University, Erbil, Iraq Mikhail Kropotov, Moscow clinical scientific center, Moscow Ilya Romanov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.10–16.25 Salivary glands, morphological characteristics Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.25–16.30 Discussion 16.30–16.45 Differential diagnosis. Salivary glands tumor. MRI criteria for assessing a potential malignant process Olga Ponomareva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.45–16.50 Discussion 16.50–17.05 Perineural feature of the minor salivary glands and assessment of treatment radicality Ekaterina Dronova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.05–17.10 Discussion 17.10–17.25 Multiparameter ultrasound examination in differential diagnosis of large salivary glands masses Ekaterina Kostromina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.25–17.30 Discussion 17.30–17.45 Salivary gland surgery Khurshid Khrwatany, Hawler Medical University, Erbil, Iraq 17.45–17.50 Discussion 17.50–18.05 Modern aspects of the salivary glands acinoscellular carcinomas diagnosis and treatment Oksana Saprina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 18.05–18.10 Discussion

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18.10–18.20 Break 18.20–19.45 Session 4. Drug therapy in patients with head and neck tumors Chairs: Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Alexander Guz, SBHI «Chelyabinsk regional clinical center for oncology and nuclear medicine», Chelyabinsk Gregori Margolin, Karolinska University Hospital, Stockholm, Sweden Pavel Svetitsky, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don 18.20–18.35 Antibiotic prophylaxis and antibiotic therapy in patients with head and neck tumors Alexander Guz, SBHI «Chelyabinsk regional clinical center for oncology and nuclear medicine», Chelyabinsk 18.35–18.40 Discussion 18.40–18.55 Evolution of head and neck squamous cell carcinoma drug treatment Svetlana Kutukova, St.Petersburg SBHI «City Clinical Oncology Center», St.Petersburg 18.55–19.00 Discussion 19.00–19.15 Interdisciplinary approach to the treatment of dermatological adverse events following targeted antitumor therapy Evgenia Shatokhina, FSBI CPE «Central State Medical Academy», Moscow 19.15–19.20 Discussion

19.20–19.40 Capabilities of narrow-spectrum and contact endoscopy in the early diagnosis of laryngeal cancer Natalia Dmitrievna, FSBI «Medical Rehabilitation Center «Barviha», Moscow 19.40–19.45 Discussion

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08.45–12.30 Problems of oncological care for population

08.45–10.45 Session 1 Chairs: Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Andrey Kaprin , FSBI NMRRC of the Ministry of Health of Russia, Moscow Vakhtang Merabishvili, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.45–08.50 Open sections. Opening Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.50–09.10 International experience in organizing cancer care Andrey Kaprin , FSBI NMRRC of the Ministry of Health of Russia, Moscow 09.10–09.30 Dynamics of morbidity, mortality and index of reliability of accounting for malignant neoplasms in the North-West Federal District of the Russian Federation Vakhtang Merabishvili, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.30–09.35 Discussion 09.35–09.50 Population cancer register of the Republic of Belarus Alesya Evmenenko, N.N. Aleksandrov Republican Scientific And Practical Center of Oncology and Medical Radiology, Minsk, Belarus 09.50–09.55 Discussion 09.55–10.10 International comparison of survival value in case of major malignant neoplasms in the «Concord» program: assessment of data quality and its impact on the results Mikhail Valkov, FSBEI of Higher Education «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk 10.10–10.15 Discussion 10.15–10.30 National cancer registry and registration of cancer diseases in the Republic of Moldova Vadim Gervas, Moldova oncological institute, Kishinev, Moldova 10.30–10.35 Discussion 10.35–10.40 Break 10.40–12.30 Session 2 Chairs: Rema Gvamichava, Georgia Screening Center, Tbilisi, Georgia Mikhail Valkov, FSBEI of Higher Education «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk

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10.40–10.55 Information system «Electronic register of cancer patients» – a tool to monitor the oncological care activities in the Republic of Kazakhstan Svetlana Ponomareva, Republican state enterprise of economic management «Republican e-health center» of the Ministry of Health of the Republic of Kazakhstan, Nur-Sultan, Kazakhstan 10.55–11.00 Discussion 11.00–11.15 Cancer screening in Georgia. Achievements and challenges Rema Gvamichava, Georgia Screening Center, Tbilisi, Georgia 11.15–11.20 Discussion 11.20–11.35 Capabilities of a regional information system for solving the issue of cancer patients registration and monitoring quality Lidiya Pikalova, RSBHI «Tomsk Regional cancer center», Tomsk 11.35–11.40 Discussion 11.40–11.55 Cancer diseases issue in Armenia. Cervical cancer screening assays Diana Andreasyan, National Institute of Health named after Academician S. Avdalbekyan, National Information Analytical Center for Healthcare (NIACH), Yerevan, Armenia 11.55–12.00 Discussion 12.00–12.10 Effective follow-up mechanisms as a tool for the successful implementation of the national oncology program and the reduction of mortality at the regional level Alla Domozhirova, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.10–12.15 Discussion 12.15–12.25 Epidemiological assessment of the National Oncology Program effucacy according to territorial cancer registries data Lyudmila Valkova, FSBEI of Higher Education «Northern State Medical University» of the Ministry of Healthcare of the Russian Federation, Arkhangelsk 12.25–12.30 Discussion 12.30–14.00 Break 14.00–16.20 Session of young cancer psychology scientists Chairs: Valentina Chulkova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Margarita Vagaytseva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Kristina Kondratieva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.00–14.10 Opening

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14.10–14.20 Psychological characteristics of adolescent patients undergoing treatment in a bone marrow transplantation department Violetta Moteva, Pavlov First St.Petersburg State Medical University, St.Petersburg 14.20–14.25 Discussion 14.25–14.35 Study of fears associated with medical manipulations in children aged 3 to 6 years Olesya Morozova, Pavlov First St.Petersburg State Medical University, St.Petersburg 14.35–14.40 Discussion 14.40–14.50 Psychogenic reactions of cancer patients associated with pain syndrome Anna Mikhalovskaya, Herzen State Pedagogical University of Russia, St.Petersburg 14.50–14.55 Discussion 14.55–15.05 Depressive psychogenic reactions in women undergoing mastectomy Valeria Mokhnina, Herzen State Pedagogical University of Russia, St.Petersburg 15.05–15.10 Discussion 15.10–15.20 Psychoemotional welfare of mothers raising children with cancer diseases Olga Alexandrova, Herzen State Pedagogical University of Russia, St.Petersburg 15.20–15.25 Discussion 15.25–15.35 Attitude to the disease and treatment in patients with prostate cancer Irina Kotovshchikova, St. Petersburg University, St.Petersburg 15.35–15.40 Discussion 15.40–15.50 Modern aspects of psychological aid in oncology. ONCOpsy project Svetlana Malysheva, «Palliative Medicine Center – Devita» LLC, St.Petersburg 15.50–15.55 Discussion 15.55–16.05 Self-informing of a cancer patient: web resources Uliana Shkatova, St. Petersburg University, St.Petersburg 16.05–16.10 Discussion 16.10–16.20 Closing remarks

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08.00–12.00 Neuroradiology

08.00–10.00 Session 1. Modern radiotherapy in neurooncology Chairs: Andrey Golanov, FSAI N.N. Burdenko Institute of Neurosurgery of the Ministry of Health of Russia, Moscow Sergey Banov, FSAI N.N. Burdenko Institute of Neurosurgery of the Ministry of Health of Russia, Moscow Sergey Novikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.00–08.15 Different fractionation modes during radiotherapy in patients with intracerebral metastases Timur Izmailov, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Moscow 08.15–08.30 Radiosurgical treatment of local recurrences in patients with brain metastases Amayak Durgaryan, FSAI N.N. Burdenko Institute of Neurosurgery of the Ministry of Health of Russia, Moscow 08.30–08.45 Possibilities of stereotactic radiation therapy in large inoperable brain metastases treatment Elena Vetlova, FSAI N.N. Burdenko Institute of Neurosurgery of the Ministry of Health of Russia, Moscow 08.45–09.00 Preoperative irradiation in the setting of metastatic brain lesion Andrey Golanov, FSAI N.N. Burdenko Institute of Neurosurgery of the Ministry of Health of Russia, Moscow 09.00–09.15 Radiation exposure of the entire brain at current state in metastatic lesions: indications and technique Sergey Banov, FSAI N.N. Burdenko Institute of Neurosurgery of the Ministry of Health of Russia Gamma Knife Center, Moscow 09.15–09.30 Radiation therapy for melanoma brain metastasis Sergey Medvedev, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 09.30–10.00 Discussion 10.00–10.45 Session 2. Is there a place for brachytherapy in the era of stereotactic radiation therapy? Chairs: Sergey Kanaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Evgeny Khmelevsky, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Yuri Mardinsky, A. Tsyb MRRC, Obninsk

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10.00–10.30 Which is the place of brachytherapy in the era of SBRT? Jose Luis Guinot, Instituto Valenciano de Oncología (I.V.O.), Valencia, Spain 10.30–10.45 Discussion 10.45–12.00 Session 3. Radiation therapy of head and neck malignant tumours Chairs: Gregori Margolin, Clinic Karolinska University Clinic, Stockholm, Sweden Anna Boyko, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Igor Gulidov, A. Tsyb MRRC, Obninsk 10.45–11.00 Sentinel lymph node guided radiation therapy of the neck: A paradigm shift Gregori Margolin, Clinic Karolinska University Clinic, Stockholm, Sweden 11.00–11.15 Capabilities of SPECT-CT imaging of signaling lymph nodes for planning radiotherapy in patients with head and neck malignant tumours Sergey Novikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.15–11.30 Efficacy and tolerane of alternative dose fractionation regimes in head and neck tumors treatment Artem Gevorkov, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia , Moscow 11.30–11.45 Radiotherapy of localized forms of head and neck squamous cell carcinoma Alexey Semenov, A. Tsyb MRRC, Obninsk 11.45–12.00 Discussion 12.00–14.30 Break

Radiation therapy of malignant tumours of various 14.30–17.45 localizations

14.30–16.15 Session 1 Chairs: Evgeny Khmelevsky, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Maia Dzhugashivili, Madrid Oncology Institute, University of Murcia, Madrid, Spain 14.30–14.45 Dose escalation justification cases under bone metastases radiation exposure Evgeny Khmelevsky, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow

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14.45–15.00 Radiation chemotherapy of patients with esophageal cancer Stanislav Ivanov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.00–15.15 Radical conservative treatment of inoperable non-small cell lung cancer. Current state of the issue Fagim Mufazalov, Republican clinical oncology center of Bashkortostan, Ufa 15.15–15.30 Repeated radiation exposure for recurrent lung cancer Danil Gogolin, A. Tsyb MRRC, Obninsk 15.30–15.45 Modern approaches of radiotherapy in lymphomas treatment Maia Dzhugashivili, Madrid Oncology Institute, University of Murcia, Madrid, Spain 15.45–16.00 Comparative analysis of the results of chemical radiation treatment of mediastinal and retroperitoneal diffuse large B-cell lymphoma Vladimir Sotnikov, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.00–16.15 Discussion 16.15–18.20 Session 2 Chairs: Sergey Tkachev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Georgiy Panshin, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Moscow Yulia Kreinina, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Obninsk 16.15–16.30 Effect of electrothermotherapy (oncothermia) on apoptosis in patients with advanced cervical cancer Yulia Kreinina, FSBI «Russian scientific center of X-radiology» of the Ministry of Healthcare of the Russian Federation, Obninsk 16.30–16.45 Modern radiotherapy technologies in the National Center of Surgery inTbilisi Besik Sokurashvil, K. Eristavi National Centre of Surgery, Tbilisi, Georgia 16.45–17.00 Modern technologies of chemoradiation therapy for colorectal cancer – new challenges: late complications Valeria Glebovskaya, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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17.00–17.15 Dose fractionation in combination radiotherapy in prostate cancer patients Ksenia Makarova, A. Tsyb Medical Radiological Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 17.15–17.30 Thermoradiotherapy in the combined treatment of patients with malignant tumours Zhanna Startseva, Cancer Research Institute of Tomsk NRMC, Tomsk 17.30–17.45 Role of positron emission tomography in the modern radiotherapy of esophageal cancer Oleg Morov, SAHI «Republican Clinical Oncology Center» of the Ministry of Health of the Republic of Tatarstan», Kazan 17.45–18.00 Project «Federal high-tech center of medical radiology in Dimitrovgrad» Elizaveta Maslukova, FSBI Federal High Technology Center of Medical Radiology FBMA Russia, Dimitrovgrad 18.00–18.20 Discussion

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08.30–12.30 Current immunotherapy. What has changed? Chairs: Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Lev Demidov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Rashida Orlova, St. Petersburg City clinical oncology center, St.Petersburg 08.30–08.50 Place of immunotherapy in malignant tumors treatment. Achievements and realia Aleksey Novik, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.50–08.55 Discussion 08.55–09.15 Lung cancer immunotherapy Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.15–09.20 Discussion 09.20–09.40 Renal cancer immunotherapy Galina Kharkevich, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.40–09.45 Discussion 09.45–10.05 Urothelial cancer immunotherapy Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.05–10.10 Discussion 10.10–10.35 Gastrointestinal tumors immunotherapy Rashida Orlova, St. Petersburg City clinical oncology center, St.Petersburg 10.35–10.40 Discussion 10.40–11.00 Immunotherapy for melanoma with rare localizations Kristina Orlova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 11.00–11.05 Discussion 11.05–11.30 Head and neck tumors immunotherapy Svetlana Kutukova, St. Petersburg City clinical oncology center, St.Petersburg 11.30–11.35 Discussion 11.35–12.00 Prognostic and predictive factors in clinical practice Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.00–12.05 Discussion

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12.05–12.25 Practical aspects of solid tumors immunotherapy (Sponsored by a company*. Not included in the program for NMOs) Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.25–12.30 Discussion 12.30–14.00 Sponsor symposium lunch* *(Not included in the CME program) 14.00–17.30 Germ cell tumors in men Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.00–14.40 Why do patients with germ cell tumors live a short life in Russia? Discussion with clinical cases analysis Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.40–14.50 Discussion 14.50–15.10 Analysis of treatment for patients with testicle germ cell tumors in the North-West region Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.10–15.15 Discussion 15.15–15.35 What is the real way out? Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.35–15.40 Discussion 15.40–16.00 Importance of germ cell tumors drug treatment Anna Semenova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.00–16.05 Discussion 16.05–16.25 Importance of germ cell tumors surgical treatment steps Vsevolod Matveev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.25–16.30 Discussion 16.30–17.30 Clinical case studies

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Session of European School of Oncology: Current issues of 09.00–12.20 gastrointestinal tumors treatment

Chairs: Sara De Dosso, Oncology Institute of Southern Switzeralnd, Bellinzona, Switzeralnd Lyubov Vladimirova, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don Alexey Karachun, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.00–09.10 Opening 09.10–09.35 Adjuvant treatment for colon cancer Sara De Dosso, Oncology Institute of Southern Switzeralnd, Bellinzona, Switzeralnd 09.35–09.40 Discussion 09.40–10.05 Fluid biopsy for gastrointestinal tumors: the present and the future Federica Di Nicolantonio, Unverisity of Turin, Turin, Italy 10.05–10.10 Discussion 10.10–10.30 Rectal cancer after neoadjuvant chemotherapy with a full clinical response: surgical treatment or dynamic surveillance? Alberto Vanelli, Valduce Hospital, Como,Italy 10.30–10.35 Discussion 10.35–10.45 Break 10.50–11.15 Classification and molecular markers for determination of GI tract neuroendocrine tumors treatment strategies Nicola Fazio, European Institute of Oncology, Milan, Italy 11.15–11.45 Immunotherapy in upper gastrointestinal cancers Sara De Dosso, Oncology Institute of Southern Switzeralnd, Bellinzona, Switzeralnd 11.45–12.10 Targeted therapy for first and second line hepatobiliary cancer Valery Breder, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.10–12.25 Discussion 12.30–14.00 Sponsor symposium lunch* *(Not included in the CME program)

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14.00–18.10 The Fifth M. L. Gershanovich Conference «GI tumours treatment individualization: from science to practice» with interactive voting

14.00–16.15 Individualization of gastrointestinal tumors systemic treatment Expert panel: Lyubov Vladimirova, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don Vera Gorbunova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Stephen Fenwick, Aintree University Hospital, Liverpool, UK Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Ilya Pokataev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.00–14.25 The role of neoadjuvant treatment of potentially resectable colorectal cancer liver metastases Stephen Fenwick, Aintree University Hospital, Liverpool, UK 14.25–14.30 Discussion 14.30–14.55 Role of antiangiogenic therapy in gastrointestinal tumors treatment (Sponsored by a company*. Not included in the CME program) Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.55–15.00 Discussion 15.00–15.20 New treatment strategies for metastatic pancreatic cancer (Sponsored by a company*. Not included in the CME program) Ilya Pokataev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.20–15.25 Discussion 15.25–15.45 Personalized treatment of metastatic esophagus and stomach cancer: capabilities of targeted therapy and immunotherapy Lyubov Vladimirova, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don 15.45–15.50 Discussion 15.50–16.10 The present and the future of drug therapy for gastrointestinal tract neuroendocrine tumors (Sponsored by a company*. Not included in the CME program) Vera Gorbunova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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16.10–16.15 Discussion 16.15–16.25 Break 16.25–18.00 Multidisciplinary session on the individualization of gastrointestinal tumors treatment Expert panel: Lyubov Vladimirova, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Larisa Bolotina, P. A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Andrey Damansky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Alexey Polikarpov, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Maxim Filipenko, FSBSI Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences, Novosibirsk 16.25–16.45 Microsatellite instability and CRC: a way to treatment personalization? Pathologist’s vision Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Opinion of a clinical oncologist Nina Tyukavina, St. Petersburg SBHI City hospital №40, St.Petersburg 16.45–16. 50 Discussion 16.50–17.10 CTC – a new biomarker in CRC treatment? Practical significance (opinion of a fundamentalist) Maxim Filipenko, FSBSI Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences, Novosibirsk Surrogate and predictive treatment response marker (opinion of a clinician) Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.10–17.15 Discussion 17.15–17.35 HIPEC for gastrointestinal tumors A surgeon’s vision Andrey Damansky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg

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Opinion of a clinical oncologist Gulfiya Teletaeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 17.35–17.40 Discussion 17.40–18.00 Hepatocellular cancer: what and to whom? Local methods: Trans-arterial chemoembolization and more A surgeon’s vision Alexey Polikarpov, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg Treatment with tyrosine kinase inhibitors. Opinion of a clinical oncologist Larisa Bolotina, P. A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia , Moscow 18.00–18.05 Discussion 18.05–18.10 Closing remarks

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JUNE, 23, SUNDAY

Symposium «Evolutionary oncology and evolutionary 09.00–18.45 virology»

09.00–15.15 Session 1. Evolutionary oncology Chairs: Andrei Kozlov, The Biomedical Center, St.Petersburg David Wheeler , Human Genome Sequencing Center, Houston, TX, USA 09.00–09.40 Stromal reserve of cancer therapy Evgeny Sverdlov, Institute of Molecular Genetics Russian Academy of Sciences, Moscow 09.40–09.45 Discussion 09.45–10.05 Cancer genomics post TCGA David Wheeler , Human Genome Sequencing Center, Houston, TX, USA 10.05–10.10 Discussion 10.10–10.35 Telomerase expression profiles in cancer progression: from functional to genetic activation Franco Maria Buonaguro, Istituto Nazionale Tumori «Fond. G. Pascale», Napoli, Italy 10.35–10.40 Discussion 10.40–11.05 Confirmation of nontrivial predictions of the hypothesis of the evolutionary role of tumors: Detection of evolutionary new genes expressed in many tumors» Andrei Kozlov, The Biomedical Center, St.Petersburg 11.05–11.10 Discussion 11.10–11.20 The study of the expression of human endogenous retroviruses as related to their evolutionary novelty Andrey Makashov, State Research Institute of Ultrapure Biologicals, St.Petersburg 11.20–11.25 Discussion 11.25–11.45 Tumors in evolution and evolution in tumors Alexei Golubev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.45–11.50 Discussion 11.50–12.05 Autoreactive T-cells in autoimmune and neoplastic diseases Evgeny Shilov , Lomonosov Moscow State University,Moscow

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12.05–12.10 Discussion 12.10–12.25 Trophoblastic glycoprotein: immunosuppressive function during trophoblast implantation and oncogenesis Alexei Shevelev, Vavilov Institute of General Genetics, Moscow 12.25–12.30 Discussion 12.30–14.00 Break 14.00–14.30 Danio rerio – development of an organism model for metastasis processes genetic regulation study and search for anti-metastatic genes Sergey Kostrov, Institute of Molecular Genetics Russian Academy of Sciences, Moscow 14.30–14.35 Discussion 14.35–14.55 Inducible zebrafish cancer model: new technologies and prospects Alexander Emelyanov, Institute For Research on Cancer and Aging, Nice, France 14.55–15.00 Discussion 15.00–15.10 The study of Tumor Specifically Expressed, Evolutionarily New genes (TSEEN genes) on the model of transgenic fish tumors (XMRK). Ekaterina Matyunina, State Research Institute of Ultrapure Biologicals, St.Petersburg 15.10–15.15 Discussion 15.15–18.50 Session 2. Evolutionary virology Chairs: Vladimir Eremin, Republican Scientific and Practical Center of Transfusiology and Medical Biotechnologies, Minsk, Belarus Andrey Komissarov, FSBI «A.A. Smorodintsev research institute of influenza» of the Ministry of Health of Russia, St.Petersburg 15.15–15.45 Ancient variants of Epstein-Barr virus: a fantasy or reality? Vladimir Gurtsevich, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.45–15.50 Discussion 15.50–16.10 Molecular epidemiology and HIV-1, HBV and HCV evolution in different risk groups in the Republic of Belarus Vladimir Eremin, Republican Scientific and Practical Center of Transfusiology and Medical Biotechnologies, Minsk, Belarus

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16.10–16.15 Discussion 16.15–16.35 The Oncological Potential of HIV-1 Maria Isaguliants , FSBI «N.F. Gamaley Research Center of Epidemiology and Microbiology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.35–16.40 Discussion 16.40–17.00 Problems and prospects of vaccine prevention of influenza in the context of evolutionary virology Yuri Vasiliev, State Research Institute of Ultrapure Biologicals, St.Petersburg 17.00–17.05 Discussion 17.05–17.15 Low genetic diversity of transmitted virus in different routes of HIV-1 infection Alexei Masharsky, State Research Institute of Ultrapure Biologicals, St.Petersburg 17.15–17.20 Discussion 17.20–17.40 Evolution of human influenza A viruses (H3N2): 50 years together Andrey Komissarov, Smorodintsev Research Institute of Influenza, St.Petersburg 17.40–17.45 Discussion 17.45–18.05 Increase genetic diversity of circulating viruses– the trend of the modern process for spread of HIV infection in Russia Natalya Gashnikova, State Research Center of Virology and Biotechnology Vectoror, Koltsovo, Novosibirsk 18.05–18.10 Discussion 18.10–18.25 Features of HPV-associated cervical cancer in immunocompromised patients Maxim Vonsky, Institute of Cytology of the Russian Academy of Science, St.Petersburg 18.25–18.50 Discussion

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08.55–12.20 A school for young oncourology doctors: Prostate cancer diagnosis

Chairs: Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Sergey Petrov , Pavlov First St. Petersburg State Medical University, St.Petersburg Iskander Abdullin, European Medical Center, Moscow 08.55–09.00 Opening 09.00–09.05 In support of prostate cancer screening and early diagnosis Maria Berkut, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.05–09.15 Negative sides of prostate cancer screening Anton Barchuk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.15–09.25 Biomarkers for early diagnosis: PSA and its derivatives Sergey Reva, Pavlov First St. Petersburg State Medical University, St.Petersburg 09.25–09.40 Biomarkers for early diagnosis: genetic tests Sergey Petrov, Pavlov First St. Petersburg State Medical University, St.Petersburg 09.40–09.55 Methods of radiodiagnosis. Role of small pelvis MRI with PSA 2 to 10 ng/ml Alexander Vasilyev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.55–10.10 Fusion biopsy. But targeted Iskander Abdullin, European Medical Center, Moscow 10.10–10.20 Fusion biopsy. Only the systemic one Marat Urmantsev, Clinic of Bashkir State Medical University, Ufa 10.20–10.30 Fusion biopsy. But combined Rustam Eloev, St. Petersburg SBHI City hospital № 40, St.Petersburg 10.30–10.40 Morphological diagnosis of prostate cancer. Criteria for trepan biopsy analysis Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.40–10.55 Early prescription of taxanes in metastatic prostate cancer (Sponsored by a company*. Not included in the program for NMOs) Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.55–11.55 Presentation of clinical cases 11.55–12.15 Discussion 12.15–12.20 Closing remarks

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Geriatrics in oncology: diagnosis, treatment, and accompanying 08.30–18.00 therapy

08.30–10.05 Session 1. Skin toxicity in the malignant neoplasms treatment Chairs: Anna Maksimova, Pavlov First St. Petersburg State Medical University, St.Petersburg Elena Lisukova, R.M. Gorbacheva Research Institute of Pediatric Oncology, Hematology and Transplantology, St.Petersburg 08.30–08.50 Skin toxicity as a side effect cytostatics and targeted drugs use. Preventive and corrective measures Olga Kunina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.55–09.05 Skin toxicity as a chemotherapy adverse event. What to do next? Katrina Katrechko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–09.30 Skin tumors prevention: the role of sunscreeners Anna Maksimova, Pavlov First St. Petersburg State Medical University, St.Petersburg 09.35–09.55 Skin manifestations of GVHD: differential diagnosis and treatment Elena Lisukova, R.M. Gorbacheva Research Institute of Pediatric Oncology, Hematology and Transplantology, St.Petersburg 09.55–10.05 Discussion 10.05–12.30 Session 2. Features of treatng elderly patient groups with various malignant neoplasms Chairs: Sergey Abashin, Federal Network of Nuclear Medicine Centers «PET Technology», Moscow Elena Tkachenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.05–10.25 Features of the course and complications in treatment of elderly patients with lymphomas Larisa Filatova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.30–10.50 Difficulties in treating patients of elderly and senile age with head and neck malignant neoplasms Alexander Mitrofanov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg

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10.55–11.05 Root of the tongue cancer in an elderly patient. Clinical case presentation Dunya Jamil Gasimly Kyzy, Krasnoyarsk Regional «A.I. Kryzhanovsky Clinical Oncologic Center», Krasnoyarsk 11.10–11.30 Practical use of cryodestruction in elderly and senile patients with malignant tumours bone metastases with various locations Dmitry Levin, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.35–11.55 Laparoscopic surgery in treatment of endometrial cancer in elderly and senile patients Yury Trifanov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.00–12.20 Appropriate volumes of oncological alertness for elderly patients Sergey Abashin, Federal Network of Nuclear Medicine Centers «PET Technology», Moscow 12.20–12.30 Discussion 12.30–14.00 Break 14.00–16.25 Session 3. Dementia in oncology Chairs: Andrey Ilnitsky, Academy of Postgraduate Education FSBI FSCC of FMBA of Russia, Moscow Svetlana Gorelik, Academy of Postgraduate Education FSBI FSCC of FMBA of Russia, Moscow 14.00–14.15 Problems of elderly cancer patients suffering from dementia. Clinical cases analysis Julia Alekseeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Nadezhda Brish, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Petimat Khabibulaeva, SBI Republican clinical oncology center, Grozny 14.20–14.40 Patient-oriented approach in dementia: position of the World Health Organization Andrey Ilnitsky, Academy of Postgraduate Education FSBI FSCC of FMBA of Russia, Moscow 14.40–14.45 Discussion 14.45–15.05 A cancer patient with and without dementia. Are there any differences in management tactics? Opinion of a geriatrician Svetlana Gorelik, Academy of Postgraduate Education FSBI FSCC of FMBA of Russia, Moscow 15.05–15.10 Discussion

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15.10–15.25 A cancer patient with and without dementia. Are there any differences in management tactics? Oncologist’s opinion Elena Tkachenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.25–15.30 Discussion 15.30–15.50 Secondary dementias in cancer patients Elvira Fesenko, Academy of Postgraduate Education FSBI FSCC of FMBA of Russia, Moscow 15.50–15.55 Discussion 15.55–16.15 Legal aspects of cancer care for patients with dementia: status and prospects Marat Filimonov, Research Medical Center «Gerontology», Moscow 16.15–16.25 Discussion 16.25–18.00 Session 4. Oncology in case of HIV infection. International solution for the problem Chairs: Vadim Rassokhin, Pavlov First St. Petersburg State Medical University, St.Petersburg Evgeny Voronin, Republican Clinical Infectious Hospital of the Ministry of Health of Russia, St.Petersburg 16.25–16.45 Cancer in case of HIV infection Vadim Rassokhin, Pavlov First St. Petersburg State Medical University, St.Petersburg 16.45–16.50 Discussion 16.50–17.10 Clinical aspects of cervical cancer in HIV-infected women Alexander Arakelyan, Pavlov First St. Petersburg State Medical University, St.Petersburg 17.10–17.15 Discussion 17.15–17.35 Head and neck tumors in HIV-infected patients Svetlana Kutukova, St. Petersburg City clinical oncology center, St.Petersburg 17.35–17.40 Discussion 17.40–17.55 Practice of lymphoproliferative diseases treatment in HIV-infected patients in St. Petersburg Anastasia Nekrasova , Pavlov First St. Petersburg State Medical University, St.Petersburg 17.55–18.00 Discussion

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09.00–19.20 Actual issues of cancer patients rehabilitation

09.00–11.40 Session 1. Practical recommendations Expert panel: Galina Ivanova, FSBEI Pirogov Russian National Research Medical University, Moscow Alexey Butenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Alexandra Stepanova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Elena Melnikova, Pavlov First St. Petersburg State Medical University, St.Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Boris Kasparov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Elena Filonenko, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Stanislav Makarenko, St.Petersburg University, St.Petersburg 09.00–09.25 Changes in the medical rehabilitation system of the Russian Federation Galina Ivanova, North-western State Medical University named after I.I. Mechnikov, St.Petersburg 09.25–09.40 International classification of functioning in cancer rehabilitation Elena Melnikova, Pavlov First St. Petersburg State Medical University, St.Petersburg 09.40–09.50 Capabilities of remote group online controlled oncological rehabilitation – Oncorehab digital platform (interim report on ROA grant) Alexey Butenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.50–10.00 Practical recommendations for rehabilitation of patients with breast cancer Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.00–10.10 Practical recommendations for rehabilitation of orthopedic cancer patients Alexandra Stepanova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.10–10.20 Practical recommendations for rehabilitation of patients with lung malignant neoplasms Boris Kasparov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.20–10.30 Practical recommendations for rehabilitation of urology cancer patients Tatiana Sivokhina, Samara Regional Clinical Cancer center, Samara

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10.30–10.40 Practical recommendations for rehabilitation of gynecology cancer patients Violetta Rodionova, Samara Regional Clinical Cancer center, Samara 10.40–10.50 Voice and speech rehabilitation for patients with head and neck tumors Elena Krasavina, Tomsk National Research Medical Center, Tomsk 10.50–11.00 Practical recommendations for rehabilitation of coloproctological cancer patients Oksana Fomenko, FSBI «A.N. Ryzhikh State scientific coloproctology center» of the Ministry of Health of Russia, Moscow 11.00–11.10 Rehabilitation of ostomy patients Elena Korolkova, St. Petersburg City clinical oncology center, St.Petersburg 11.10–11.20 Role of osteomodifying agents in rehabilitation of cancer patients Albina Zhabina, St. Petersburg City clinical oncology center, 11.20–11.30 Successful integration of oncological rehabilitation into a sanatorium- resort system Rashida Orlova, St. Petersburg City clinical oncology center, St.Petersburg 11.30–11.40 Discussion 11.40–13.00 Session 2. Telemedicine and rehabilitation Chairs: Galina Ivanova, Research Institute of Institute of Cerebrovascular Pathology and Stroke Pirogov Russian National Research Medical University, Moscow Alexey Butenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Irina Kargalskaya, «Hello» – Cancer patients association, Moscow Anna Malkova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.40–11.55 Tele-rehabilitation as a tool to ensure continuity, phasing, succession and personalized treatment Irina Kargalskaya, «Hello» – Cancer patients association, Moscow 11.55–12.10 Onkonet platform is a set of assistance measures for post-hospital remote monitoring of patients during chemotherapy and video training content for individual outpatient rehabilitation of a cancer patient Sergey Shinkarev, SHI «Lipetsk regional cancer center», Lipetsk

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12.10–12.20 Role of telemedicine center in advising patients on rehabilitation issues; tele-education of sanatorium-resort staff on effective cancer rehabilitation strategies Ilmira Gilmutdinova, FSBI «National Medical Research Center for Rehabilitation and Balneology» of the Ministry of Health of Russia, Moscow 12.20–12.30 Role of remote methods in the voice rehabilitation of patients after larynx removal. Possibility of voice communication establishing Ekaterina Osipenko, Scientific and Clinical Center of Otorhinolaryngology of the Federal Medico-Biological Agency of the Russian Federation, Moscow 12.30–12.40 Surgery, chemotherapy, radiation exposure. Nutritional support as an essential part of oncology rehabilitation. Keeping of an electronic diary by a patient for nutrition control Olga Obukhova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.40–12.50 Experience of a multidisciplinary experts team in the domestic individualized online controlled rehabilitation of patients living in remote areas of the Ivanovo region Julia Kulikova, Ivanovo Regional Rehabilitation Center FSBHI MC RESHMA, Ivanovo

12.50–13.00 Discussion 13.00–14.00 Break 14.00–16.00 Session 3. Oncopsychology Chairs: Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Valentina Chulkova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Tatiana Karavaeva, V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology, St.Petersburg 14.00–14.05 Opening Valentina Chulkova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.05–14.15 Mental trauma in cancer patients Elena Pestereva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.15–14.25 Targets of psychotherapy for comorbid PTSD in cancer patients Tatiana Karavaeva, V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology, St.Petersburg 14.25–14.35 Differentiated approach in the model of psychological and social cancer patients support Ilmira Khusainova, Kazakh Research Institute of Oncology and Radiology, Almaty, Kazakhstan

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14.35–14.45 Features of psychological rehabilitation of cancer patients during inpatient treatment Margarita Vagaytseva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.45–14.55 Art therapy in the complex cancer patients rehabilitation Galina Tkachenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.55–15.05 A doctor and an excessively informed patient. How to build an effective interaction? Marina Ivashkina, RSMU, Institute of Psychotherapy and Clinical Psychology, «Clear morning» service, Moscow 15.05–15.15 Hypochondriacal reactions of cancer patients Kristina Kondratieva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.15–15.25 Parental attitudes during rehabilitation of children who have undergone a cancer disease Olga Alexandrova, FSBEI HE Herzen State Pedagogical University of Russia, St.Petersburg 15.25–15.35 Results of doctor-patient communication efficacy study in the St. Petersburg clinical scientific and practical center for specialized medical care Anton Karpov, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St.Petersburg 15.35–15.45 Comparative analysis of the life quality of patients with metastatic spinal lesions before and after surgical treatment Ekaterina Usmanova, International Preschool, Moscow 15.45–16.00 Discussion 16.00–19.20 Session 4. Patient session

Chairs: Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Irina Borovova, Transregional non-commercial institution «Hello» – Cancer patients association, Moscow Nikolai Dronov, Transregional social movement «Movement Against Cancer, Moscow 16.00–16.05 Opening Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg

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16.05–16.20 Feedback as a tool to increase the efficacy of the Federal project «Fight against cancer» Nikolai Dronov, Transregional social movement «Movement Against Cancer, Moscow 16.20–16.35 Rehabilitation opportunities for cancer patients Irina Borovova, Transregional non-commercial institution «Hello» – Cancer patients association, Moscow 16.35–16.50 Patients sense of security – how it impacts on health results, how we raise it? Magdalena Elżbieta Krząścik-Sulikowska, Alivia – Fundacja Onkologiczna, Warsaw, Poland 16.50–17.05 Dance with Cancer as the Patient Association Ar Fatma Figen, Dance with Cancer, Ankara, Turkey 17.05–17.20 Post Traumatic Stress Disorder in oncological patient and Innovative Confrontation Program by K.E.F.I Association Vasiliki Koumantaki, K.E.F.I of Athens Assosiation of Cancer Patient, Athens, Greece 17.20–17.30 Rehabilitation of female cancer patients. Project «You are special» Olga Vostrikova, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 17.30–17.40 Public group «Cancer can be cured» Olga Chernyak, «Cancer can be cured», Moscow 17.40–17.50 Hot line as a tool to support the patient at all the treatment stages Olga Goldman , «Clear morning», Moscow 17.50–18.00 «Movement Against Cancer» – actual care for cancer patients Marina Rumyantseva , Transregional social movement «Movement Against Cancer», St.Petersburg 18.00–18.10 Ability to live in the period of disease and rehabilitation Veronika Sevostyanova, «Cancer can be cured», St.Petersburg 18.10–18.25 Online training and maintenance of peer educators in oncology through an online learning platform Tatiana Zolotoreva, Transregional social movement «Together Against Cancer», Krasnoyarsk 18.25–18.35 Innovative program of support for people with malignant neoplasms in the Center for social and psychological support «Cancer can be defeated» for cancer patients and their families, living in the Zakamsky region of the Republic of Tatarstan Rumiya Taymasova, Regional public organization of the Republic of Tatarstan «Cancer can be defeated», Naberezhnye Chelny, Republic of Tatarstan

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18.35–18.45 Introduction of peer education practice in oncology into specialized medical institutions. First year results and future plans Tatiana Golovanova, Women support foundation «Aleksandra», Moscow 18.45–18.55 Triangle of fate and anticancer fight – about socially supported life strategies for cancer patients Olga Yuskevich, Autonomous non-commercial organization «We are together – Bez Berghe», Kazan, Republic of Tatarstan 18.55–19.00 Creativity as a social rehabilitation tool Julia Ivashkevich, Autonomous non-commercial organization «We are together – Bez Berghe», Kazan, Republic of Tatarstan 19.00–19.10 Discussion 19.10–19.20 Closing remarks

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Hall Green 5

Business etiquette 10.00–12.00 (Not included in the CME program) Chair: Luiza Gatova, «Comme il faut» etiquette school, Krasnodar 10.00–10.45 Basics of business etiquette, effective communication, doctor’s behavior at work, when travelling, at a conference in Russia and abroad/Business cards and business correspondence Luiza Gatova, «Comme il faut» etiquette school, Krasnodar 10.45–11.00 Break 11.00–11.45 Communication with colleagues: taboo conversation topics and small talk. Cocktail, coffee break, business lunch in a restaurant – how to behave oneself. Business presents Luiza Gatova, «Comme il faut» etiquette school, Krasnodar 11.45–12.00 Discussion 12.00–14.00 Role of medical insurance organizations in protection of the cancer patients rights *(Not included in the CME program) Chairs: Nikolai Dronov, Interregional social movement «Movement against cancer», Moscow Dmitry Kuznetsov, All-Russia Insurers Association, Moscow 12.00–12.30 The fight against cancer. Formation of a system for the protection of patients’ rights on the basis of control and expert measures in order to ensure the quality of cancer care in accordance with the ROA clinical guidelines Aleksey Starchenko, Capital MC, LLC, Moscow 12.30–12.50 Expert control of cancer cases: introduction of new technological tools Yuri Brudastov, «Insurance Company Sogaz-Med» JSC, Moscow 12.50–13.10 Issues of late cancer detection in the regions of the Russian Federation Alexey Bereznikov, AlfaStrakhovanie OMS, LLC, Moscow 13.25–13.50 Control of volumes, conditions and quality of medical care for patients with cancer of the North-West Federal District and St. Petersburg Alexandra Repina, St. Petersburg CMS Regional Fund, St.Petersburg 13.50–14.00 Discussion

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Hall Green 6+7

Current issues of morphological diagnosis in oncology 09.00–18.00 practice

09.00–12.30 Section 1. Informatization in anatomic pathology *(Not included in the CME program) Chairs: Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Asel Kudaibergenova , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Ekaterina Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.00–09.20 Place and modern capabilities of information systems in anatomic pathology Mikhail Kaufman, «TehLAB», LLC, St.Petersburg 09.20–09.25 Discussion 09.25–09.45 LAN in PAD: theory and practice Andrey Vasilenko, «BioVitrum», OOO», St.Petersburg 09.45–09.50 Discussion 09.50–10.10 Macrophotography systems: expectations and reality Elizaveta Razvarina, «BioVitrum», OOO», St.Petersburg 10.10–10.15 Discussion 10.15–10.45 Break 10.45–11.05 Digital pathologicoanatomic case: features and requirements Elizaveta Razvarina, «BioVitrum», OOO», St.Petersburg 11.05–11.10 Discussion 11.10–11.30 SMART – Pathoanatomical department automation. Practice of Vivantes GmbH, Berlin Hermann Herbst, Vivantes, Berlin, Germany 11.30–11.35 Discussion 11.35–11.55 Tracking inf PAD Pavel Kislov, «BioLine», LLC, St.Petersburg 11.55–12.00 Discussion 12.00–12.20 MIS – LIS integration: personal experience Ekaterina Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.20–12.25 Discussion

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Hall Green 6+7

12.30–14.00 Break 14.00–14.25 Section 2. Current classifications in oncomorphology: trends, approaches, changes Chairs: Vadim Baykov, R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg Andrey Mihetko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation,St.Petersburg 14.00–14.20 Modern systems for cytomorphological assessment of tumors Alina Nefedova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.20–14.25 Discussion 14.25–15.50 Session 3. Tumors of hematolymphoid system 14.25–14.45 Aggressive B-cell lymphomas Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.45–14.50 Discussion 14.50–15.10 Indolent B-cell lymphomas Ilya Polyatskiy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.10–15.15 Discussion 15.15–15.45 Modern classification of myeloproliferative diseases and myelodysplastic syndromes Vadim Baykov , R.M. Gorbacheva Scientific Research Institute of Children Oncology, Hematology and Transplantation, St.Petersburg 15.45–15.50 Discussion 15.50–16.30 Break 16.30–18.00 Section 4. Thyroid tumors Chairs: Alexander Abrosimov, FSBI «National Medical Research Center of Endocrinology», St.Petersburg Sergey Vorobyov, National center for clinical morphological diagnosis, St.Petersburg Asel Kudaibergenova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.30–17.00 Histological classification of thyroid tumors (2017): new about the previously known or a reflection of the uncertainty of diagnostic entities Sergey Vorobyov, National center for clinical morphological diagnosis, St.Petersburg

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Hall Green 6+7

17.00–17.05 Discussion 17.05–17.35 Clinical and morphological features of recurrent papillary thyroid cancer and BRAF status Alexander Abrosimov, FSBI «National Medical Research Center of Endocrinology», St.Petersburg 17.35–17.40 Discussion 17.40–18.00 Closing

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Hall Green 8

Nuclear medicine in malignant tumors diagnosis and 08.30–12.30 treatment

08.30–10.30 Session 1 Chairs: Pavel Krzhivitsky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Daria Ryzhkova, FSBI Almazov National Medical research Center of the Ministry of Healthcare of the Russian Federation, St.Petersburg Vyacheslav Sukhov, FSBI «A.M. Nikiforov All-Russia center of emergency and radiation medicine» of Ministry of Emergency Situations of Russia, St.Petersburg 08.30–08.45 Diagnosis of prevalence of the process in patients with breast cancer using SPECT-CT. Experience of FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation Pavel Krzhivitsky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 08.45–09.00 Theranostics of malignant neoplasms. Current state and development prospects Andrey Stanzhevsky, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg 09.00–09.15 PET-CT with 18F-DOPA in the neuroendcrine tumors diagnosis Daria Ryzhkova, FSBI Almazov National Medical research Center of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.15–09.30 SPECT with 99mTc-1-thio-D-glucose in the evaluation of the malignant tumors metabolism Roman Zelchan, Tomsk National Research Medical Center, Tomsk 09.30–09.45 SPECT/CT in differential diagnosis of skeleton focal lesions Alexey Ryzhkov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 09.45–10.00 Current applications of gallium-68 labelled radiopharmaceuticals for PET Jan-Noël Talbot, Hopitaux Universitaires Est Parisien, Paris, France 10.00–10.15 Discussion 10.15–10.30 Break 10.30–12.30 Session 2 Chairs: Valery Krylov, A. Tsyb Medical Radiological Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk Andrey Stanzhevsky, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg

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Hall Green 8

10.30–10.45 Radioiodine therapy for thyroid cancer. Current issues of treatment and observation of patients Tamara Geliashvili, A. Tsyb Medical Radiological Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 10.45–10.50 Discussion 10.50–11.05 Prostate cancer Theranostics with PSMA compounds Kalevi Kairemo, MD Anderson Cancer Center, Helsinki, Finland 11.05–11.10 Discussion 11.10–11.25 Radionuclide therapy for bone metastases. Current approaches Valery Krylov, A. Tsyb Medical Radiological Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Obninsk 11.25–11.30 Discussion 11.30–11.45 Theranostic in prostate cancer: comparison of theranostical pairs PSMA- 68Ga/177Lu and PSMA-18F/177Lu Vyacheslav Sukhov, FSBI «A.M. Nikiforov All-Russia center of emergency and radiation medicine» of Ministry of Emergency Situations of Russia, St.Petersburg 11.45–11.50 Discussion 11.50–12.05 PSMA PRLT-Augmented Treatment by Individualized Protocol Tandem Alpha-Beta PRLT and Co-Medications Samer Ezziddin, Saarland University Hospital, Germany 12.05–12.10 Discussion 12.10–12.25 Clinical use of Digital PET: Future of molecular imaging (Sponsored by a company*. Not included in the program for NMOs) Ignasio Carrio, University of Barcelona, Barcelona, Spain 12.25–12.30 Discussion and conclusion 12.30–14.00 Break 14.30–18.00 Interventional radiology in oncology: correction of complications at various stages of cancer patients treatment 14.30–16.25 Session 1. Endovascular interventions for bleeding and cardiovascular complications in cancer patients Chairs: Boris Dolgushin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Julia Suvorova, St. Petersburg Clinical Hospital of the Russian Academy of Sciences, St.Petersburg Kirill Kozlov, St. Petersburg Institute of Bioregulation and Gerontology, St.Petersburg

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14.30–14.50 X-ray endovascular interventions for tumor bleeding Julia Suvorova, St. Petersburg Clinical Hospital of the Russian Academy of Sciences, St.Petersburg 14.50–14.55 Discussion 14.55–15.15 Role of interventional radiology methods for diagnosis and treatment of upper and lower gastrointestinal bleeding in cancer patients Pavel Balakhnin, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St.Petersburg 15.15–15.20 Discussion 15.20–15.40 Correction of venous thromboembolic complications in cancer patients. Prevention of pulmonary embolism using cava filters implantation Valery Cherkasov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.40–15.45 Discussion 15.45–16.00 Endovascular treatment of abdominal aortic aneurysms in cancer patients Mikhail Generalov, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg 16.00–16.05 Discussion 16.05–16.20 Cardiotoxic coronary disease on the background of chemotherapy in cancer patients Andrey Smolnikov, FSHI «Velikolukskaya interdistrict hospital», Vylikie Luki 16.20–16.25 Discussion 16.25–18.00 Session 2. Extravascular interventions for correction of stenoses and strictures in cancer patients Chairs: Boris Dolgushin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Pavel Balakhnin, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St.Petersburg 16.25–16.45 Photodynamic therapy in Klatskin tumors treatment Olga Sergeeva, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.45–16.50 Discussion 16.50–17.10 Interventional radiological maneuvers in oncourology Igor Pogrebnyakov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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Hall Green 8

17.10–17.15 Discussion 17.15–17.30 Use of magnetic anastomoses and stenting in case of bile duct strictures Valery Cherkasov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 17.30–17.35 Discussion 17.35–17.55 Hollow organs stenting in oncology: Role of X-ray surgery technologies Pavel Balakhnin, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St.Petersburg 17.55–18.00 Discussion

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Hall Green 9

09.00–18.00 Scientific practical conference of the Problem Commission «Head and neck tumors» of the Scientific Council on malignant neoplasms of the Russian Academy of Sciences and the Ministry of Health of Russia «Modern methods of diagnosis and treatment of recurrences and distant head and neck malignant neoplasms metastases» *(Not included in the CME program) 09.00–12.30 Session 1

Chairs: Ali Mudunov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Evgeny Choynzonov, Tomsk National Research Medical Center», Tomsk Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.00–09.10 Opening Ali Mudunov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation,Moscow 09.10–09.25 Capabilities of neutron therapy in treatment of recurrent head and neck tumors Olga Gribova, Evgeny Choynzonov, Zhanna Startseva, Tomsk National Research Medical Center», Tomsk 09.25–09.30 Discussion 09.30–09.45 Rare and recurrent head and neck tumors. Diagnosis and treatment Valery Novikov. Evgeny Choynzonov, Anastasia Ryabova, Tomsk National Research Medical Center, Tomsk 09.45–09.50 Discussion 09.50–10.05 Treatment of children with head and neck soft tissues recurrent sarcomas Vladimir Polyakov, Tatiana Gorbunova, Marina Osipova, Oleg Merkulov, Dmitry Buletov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.05–10.10 Discussion 10.10–10.25 Causes and frequency of thyroid cancer recurrence in children Vladimir Polyakov, Ruslan Shishkov, Natalia Ivanova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 10.25–10.30 Discussion 10.30–10.45 Combined treatment of recurrent head and neck cancer Igor Reshetov, Natalia Sukortseva, Dmitry Svyatoslavov, Aleksander Shevalgin, Igor Bykov, Julia Agakina, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow

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Hall Green 9

10.45–10.50 Discussion 10.50–11.10 Break 11.10–11.25 Multidisciplinary approach to treatment of recurrent head and neck squamous cell carcinoma in a clinical oncology hospital Sergey Kravtsov, FSHI City Clinical Oncological Hospital № 1, Moscow 11.25–11.30 Discussion 11.30–11.45 Current capabilities of CT and MRI in diagnosis of head and neck malignant tumors recurrence Ekaterina Dronova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 11.45–11.50 Discussion 11.50–12.05 Features of reparative interventions in patients with recurrent malignant tumors in the midface and upper jaw areas Ali Mudunov, Mikhail Bolotin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.05–12.10 Discussion 12.10–12.25 Treatment of recurrent tumors of the adnexa Marina Engibaryan, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don 12.25–12.30 Discussion 12.30–14.00 Break 14.00–16.00 Session 2 Chairs: Igor Reshetov, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow Andrey Polyakov, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Marina Engibaryan, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don 14.00–14.15 Controversial issues of metastatic squamous cell head and neck cancer treatment Andrey Polyakov, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 14.15–14.20 Discussion

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14.20–14.35 Therapeutic decision for patients with head and neck recurrent basal cell and squamous cell carcinoma Ilya Pustynsky, Ekaterina Kiva, Anton Dvornikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 14.35–14.40 Discussion 14.40–14.55 Echosonography in diagnosis of laryngeal cancer recurrence Leonid Kozhanov, Marina Mularets, FSHI City Clinical Oncological Hospital № 1, Moscow 14.55–15.00 Discussion 15.00–15.15 Problems and solutions in precision radiation therapy planning for recurrent head and neck tumors Denis Larinov, Rafael Faysullin, «OncoStop» clinic, Moscow 15.15–15.20 Discussion 15.20–15.40 Drug therapy for recurrent and metastatic basal cell skin cancer. Treatment tactics selection Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.40–16.00 Break 16.00–18.00 Session 3 Modern methods of diagnosis and treatment of recurrences and distant metastases of head and neck malignant neoplasms Chairs: Pavel Svetitsky, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federation, Rostov-on-Don Aleksander Minkin, FBI AO Arkhangelsk Clinical Cancer Center, Arkhangelsk Elena Novozhilova, State Budget healthcare institution Moscow State Oncology Hospital № 62 of the Moscow City Healthcare Department, Moscow 16.00–16.15 Analysis of frequency of malignant head and neck tumors distant metastasis and recurrence in the Arkhangelsk region from 2008 to 2018; SBI JSC «Arkhangelsk Clinical Oncology Center», FSBEI of Higher Education «Northern State Medical University» Mikhail Vereshchagin, Aleksander Minkin, Dmitry Staritsyn, FBI AO Arkhangelsk Clinical Cancer Center, Arkhangelsk 16.15–16.20 Discussion 16.20–16.35 Justification of surgical approach to the treatment of recurrence of oral cavity malignant tumors Irina Rebrikova, Andrey Polyakov, Mikhail Ratushny, Oleg Matorin, Aleksander Mordovskiy, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 16.35–16.40 Discussion

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16.40–16.55 Treatment outcomes improvement in patients with recurrent advanced oral and oropharyngeal cancer Pavel Svetitsky, Rostov Research Institute of Oncology of the Ministry of Healthcare of the Russian Federationб Rostov-on-Don 16.55–17.00 Discussion 17.00–17.15 TLM-surgery in laryngeal cancer recurrence conservative treatment Elena Novozhilova, Aleksander Fedotov, Ivan Chumakov, Andrey Khoteev, Sergey Sokolov, Konstantin Chudakov, SBHI Moscow city oncology hospital № 62 of the Moscow Healthcare Department, Moscow 17.15–17.20 Discussion 17.20–17.35 Relapse and continued growth of midface, oral cavity, larynx cancer. Therapeutic decision, solutions to organizational problems Viktor Pismenny, Ivan Pismenny, NHI «Road Clinical Hospital at Samara station of Russian Railways», Samara 17.35–18.00 Discussion, closing remarks

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09.00–17.00 КриогеCryogenic technologies in oncology

09.00–12.30 Session 1 Chairs: Franco Lugnani, Casa di Cura SALUS, Trieste, Italy Georgiy Prokhorov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Alexey Zhao, FSBI «A.V. Vishnevskiy NMRC of surgery» of the Ministry of Defense of the Russian Federation, Moscow 09.00–09.10 Opening Georgiy Prokhorov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.10–09.30 Modern Cryotechnology for Cancer. World Experience Franco Lugnani, Casa di Cura SALUS, Trieste, Italy 09.30–09.35 Discussion 09.35–09.50 Scientific and technical domestic developments in cryosurgery Georgiy Prokhorov FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.50–09.55 Discussion 09.55–10.10 Unsolved cryosurgery issues Denis Prokhorov, FSBI «A.M. Granov Russian Scientific Center of Radiology and Surgical Technologies» of the Ministry of Health of the Russian Federation, St.Petersburg 10.10–10.15 Discussion 10.15–10.30 Features of pathomorphosis and regeneration after cryotherapy Anna Artemyeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.30–10.35 Discussion 10.35–10.50 Bone strength changes after exposure to cold. Experimental data Anna Arhitskaya, Chuvash State University named after I.N. Ulyanov, Cheboksary 10.50–10.55 Discussion 10.55–11.10 CT navigation methods for stereotactic paracentetic cryoablation of bone tumors Ilya Burovik, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.10–11.15 Discussion

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Hall Green 10

11.15–11.30 Ultrasonic navigation during paracentetic access to soft tissue tumors Alexander Vasilyev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.30–11.35 Discussion 11.35–11.50 Renal function after paracentetic cryoablation of a tumor Polina Lushina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.50–11.55 Discussion 11.55–12.10 Flat detector CT controlled percutaneous cryoablation in treatment of pain in metastatic bone lesions Pavel Balakhnin, SBHI «St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological)», St.Petersburg 12.10–12.15 Discussion 12.15–12.25 Cryoablation of metastatic bone tumors in palliative therapy Dmitry Levin, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.25–12.30 Discussion 12.30–14.00 Break 14.00–17.00 Session 2 Chairs: Franco Lugnani, Casa di Cura SALUS, Trieste, Italy Mukhail Khanevich, Russian Hematology and Transfusion Medicine Research Institute, St.Petersburg Alexey Zhao, FSBI «A.V. Vishnevskiy NMRC of surgery» of the Ministry of Defense of the Russian Federation, Moscow 14.00–14.15 Cryo exposure for liver wound surface in borderline resectable colorectal cancer metastases Yuri Gulyaev, St. Petersburg City clinical oncology center, St.Petersburg 14.15–14.20 Discussion 14.20–14.35 Cryodestruction of pancreatic metastases Dmitry Ionkin, FSBI «A.V. Vishnevskiy NMRC of surgery» of the Ministry of Defense of the Russian Federation, Moscow 14.35–14.40 Discussion 14.40–14.55 Combination of resection with local thermal destruction methods in treatment of primary liver cancer and colorectal cancer metastases Dmitry Ionkin, FSBI «A.V. Vishnevskiy NMRC of surgery» of the Ministry of Defense of the Russian Federation, Moscow

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14.55–15.00 Discussion 15.00–15.15 Cryodestruction of hepatic malignant tumors: preliminary results of MRI monitoring at treatment stages Valeria Vdovenko, FSBI «A.V. Vishnevskiy NMRC of surgery» of the Ministry of Defense of the Russian Federation, Moscow 15.15–15.20 Discussion 15.20–15.35 Cryosurgical treatment methods in patients with head and neck skin tumors Rustam Nazhmudinov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.35–15.40 Discussion 15.40–15.55 Possibilities of paracentetic cryoablation in patients with tongue squamous cell carcinoma Semen Artemyev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.55–16.00 Discussion 16.00–16.05 Cryogenic therapy for squamous cell skin cancer Olga Baykalova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.05–16.10 Discussion 16.10–16.25 Long-term results of cryogenic treatment for patients with recurrent head skin cancer Ilya Pustynsky, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 16.25–16.30 Discussion 16.30–16.45 Discussion of a plan for future conferences and workshops Georgiy Prokhorov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.45–16.50 Discussion 16.50–17.00 Closing

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Hall Red 8

09.00–15.30 Perspectives of geroprotectors as anti-cancer agents

Chairs: Vladimir Anisimov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Claudio Franceschi, Bologna University, Bologna, Italy 09.00–09.30 Inflamaging as an aging and carcinogenesis factor Claudio Franceschi, Bologna University, Bologna, Italy 09.30–10.00 Perspectives of geroprotectors as anti-cancer agents Vladimir Anisimov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.00–10.30 Intersection of molecular mechanisms of carcinogenesis and aging Alexey Golubev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.30–10.50 Discussion 10.50–11.10 Metformin in prevention of cancer and aging Irina Popovich, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.10–11.30 Break 11.30–11.50 Repamycin in prevention of cancer and aging Maria Yurova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 11.50–12.20 Melatonin and epitalon in prevention of cancer and aging in case of light desynchronosis Irina Vinogradova, Petrozavodsk State University, Petrozavodsk 12.20–12.40 Metformin and melatonin in complex therapy of breast cancer Mikhail Osipov , FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 12.40–14.00 Break 14.00–14.20 Natural and nutritional drugs in prevention of cancer and aging Vladimir Bespalov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.20–14.40 Anticarcinogenic and geroprotective properties of polyphenolic plant compounds Andrey Panchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.40–15.00 Phytodrugs in prevention of cancer and aging Grigory Tochilnikov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.00–15.30 Discussion

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Hall Red 9

09.30–17.15 Conference on Fundamental Oncology «Petrovskie chtenia» (School of Young Scientists) Supported by the RSF (Grant №17–75–30027)

09.30–10.45 Session 1 Chairs: Lev Bershteyn, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Sergey Moshkovsky, FSBEI Pirogov Russian National Research Medical University of the Ministry of Healthcare of the Russian Federation, Moscow 09.30–10.10 Proteomics in the search for biomarkers of malignant tumors Sergey Moshkovsky, FSBEI Pirogov Russian National Research Medical University of the Ministry of Healthcare of the Russian Federation, Moscow 10.10–10.15 Discussion 10.15–10.25 Endogenous fluorescence based metabolic imaging for monitoring antitumor therapy efficacy Marina Shirmanova, FSBEI Privolzhskiy Research Medical University of the Ministry of Health of Russia Nizhny, Novgorod 10.25–10.30 Discussion 10.30–10.40 Blood exosomes of cancer patients stimulate angiogenesis in vitro Svetlana Tamkovich, Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences, Novosibirsk 10.40–10.45 Discussion 10.45–11.00 Break 11.00–12.30 Session 2 Chairs: Mikhail Krasilnikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Nikolay Litvyakov, Tomsk National Research Medical Center, Tomsk 11.00–11.25 Rearrangement of intracellular signaling pathways as a tumor progression factor Mikhail Krasilnikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 11.25–11.30 Discussion 11.30–11.40 Expression of the mammary gland stem proteins in non-stem tumor cells as a new in situ marker of tumor metastasis Nikolay Litvyakov, Tomsk National Research Medical Center, Tomsk

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Hall Red 9

11.40–11.45 Discussion 11.45–11.55 Expression of tryptophan -2, 3-dioxygense (TDO) in metastasis tumor Mizue Terai, Thomas Jefferson University, Philadelphia, USA 11.55–12.00 Discussion 12.00–12.25 Introduction to experimental primatology Sergey Orlov, Research institute of medical primatology, 12.25–12.30 Discussion 12.30–14.00 Break 14.00–15.30 Session 3 Chairs: Nadezhda Cherdyntseva, Tomsk National Research Medical Center, Tomsk Sergey Orlov, Research institute of medical primatology, Sochi 14.00–14.40 Interaction of a tumor and its microenvironment: on the way to antitumor therapy optimization Nadezhda Cherdyntseva, Tomsk National Research Medical Center, Tomsk 14.40–14.45 Discussion 14.45–14.55 Search for missing genetic determinants of hereditary breast cancer with the help of whole-exome sequencing Ekaterina Kuligina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 14.55–15.00 Discussion 15.00–15.10 Allelic imbalance of expressed clinically significant germline single nucleotide variants in hepatocellular carcinoma Olga Krivtsova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.10–15.15 Discussion 15.15–15.25 Chemical carcinogenesis models in mice Andrey Panchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 15.25–15.30 Discussion 15.30–16.00 Break

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16.00–17.15 Session 4

Chairs: Alexander Ivantsov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Jamila Polatova, Republican specialized scientific and practical medical center of oncology and medical radiology, Tashkent, Uzbekistan 16.00–16.10 Expression of von Hippel-Lindau protein in the tissue of renal cancer patients, connection with transcriptional, growth factors and components of the AKT/m-TOR signaling pathway Lyudmila Spirina, Tomsk National Research Medical Center, Tomsk 16.10–16.15 Discussion 16.15–16.25 Clinical and morphological features of BRCA1-associated tumors Alexander Ivantsov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 16.25–16.30 Discussion 16.30–16.40 Osteosarcoma in children and its molecular genetic characteristics Jamila Polatova, Republican specialized scientific and practical medical center of oncology and medical radiology, Tashkent, Uzbekistan 16.40–16.45 Discussion 16.45-16.55 Rational approach to diagnostics of BRCA1-associated ovarian cancer Elena Savonevich, Grodno Medical University, Grodno, Belarus 16.55-17.00 Discussion 17.00-17.10 Complex detection of EGFR, KRAS, BRAF and HER2 mutations in non- small cell lung cancer patients Vladimir Nazarov, Pavlov First St. Petersburg State Medical University, St.Petersburg 17.10-17.15 Discussion

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Hall Red 10

09.00–12.10 Pharmacoeconomics in oncology

Chairs: Andrey Pavlysh, North-western State Medical University named after I.I. Mechnikov, St.Petersburg Aleksey Kolbin, Pavlov First St. Petersburg State Medical University, St.Petersburg 09.00–09.30 Targeted therapies and immunotherapies in oncology – how is HTA assessing these interventions in order to inform decisions Finn Boerlum Kristensen, University of Southern Denmark, Copenhagen, Denmark 09.30–09.50 Assessment of possibility of meeting the need for modern anticancer drugs, taking into account the expected patent protection expiration dates Maria Avksenteva, FSBI «Center for Healthcare Quality Assessment and Control» of Healthcare Ministry of Russia, Moscow 09.50–10.10 Results of cancer care performance indicators modeling in implementation of innovative technologies for metastatic lung cancer treatment Olga Zelenova , FSBI «Central R&D institute for healthcare organization and informatization» of the Ministry of Health of Russia, Moscow 10.10–10.30 Clinical and economic assessment of modern medicinal technologies in haemato-oncology Sergey Zyryanov, FSAEI RUDN University of Ministry of Education and Science of Russia, Moscow 10.30–10.50 «Efficacy-effectiveness gap» concept (EEG). Location at Healthcare technology assessment Aleksey Kolbin, Pavlov First St. Petersburg State Medical University, St.Petersburg 10.50–11.10 Hospitals-based Healthcare Technology Assessment. Prospects for implementation in the university Andrey Pavlysh, North-western State Medical University named after I.I. Mechnikov, St.Petersburg 11.10–11.30 Decision-taking theory in pharmacoeconomics Svyatoslav Plavinsky, North-western State Medical University named after I.I. Mechnikov, St.Petersburg 11.30–11.50 Pharmacoeconomics of HPV-associated cancer: prevention or therapy? Alla Rudakova , FSBEI Saint Petersburg State Chemical Pharmaceutical Academy of the Ministry of Healthcare of Russia, St.Petersburg 11.50–12.10 Discussion 12.30–14.00 Break

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14.00–15.20 Why do patients resort to pseudoscientific cancer treatments? Opinion based on scientific communication, sociology and neuropsychology *(Not included in the CME program)

Moderator: Elizaveta Dubovik, «Severgroup Medicine», LLC, St.Petersburg 14.05–14.20 Pseudo-science in medical communication and journalism Daniela Ovadia, Agency Zoe, Milan, Italy 14.20–14.35 A physician, a patient, and the Internet: search for understanding with a patient committed to pseudoscientific treatment Andrey Pavlenko, St. Petersburg State University «N.I. Pirogov Clinic of High Medical Technologies», St.Petersburg 14.35–14.50 Research of doctor and patient relationships in the context of parascientific ideas about cancer Sergey Startsev, National Research University «Higher School of Economics», Moscow 14.50–15.05 Pseudoscientific treatment methods and irrational decisions in medicine from the neuropsychology viewpoint Gabriella Bottini, University of Pavia, Pavia, Italy 15.05–15.20 Discussion

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Hall Red 11

09.00–14.00 Session with European Organization for Trophoblastic Dis- ease (EOTTD)

09.00–09.30 Key-note lecture: Medical treatment of Germ Cell Tumors in women Michael J Seckl, EOTTD, London, UK 09.30–14.00 Teaching Lesson in Gestational Trophoblastic Disease (GTD) Chairs: Michael J Seckl, EOTTD, London, UK Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Adilia Urmanceeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Elena Ulrikh FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.30–09.50 Etiology of GTD. The role of pathology/genetics in diagnosis Elena Bakhidze, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 09.50–10.10 HcG assays Evgeniya Cyrlina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.10–10.30 Management of Low risk disease Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 10.30–10.50 Management of High and ultra-high risk disease Matt Winter, EOTTD, London, UK 10.50–11.10 Surgery in treatment of GTD Leon Massuger, EOTTD, London, UK 11.10–11.30 Rare forms of GTD Michael J Seckl, EOTTD, London, UK 11.30–12.30 Clinical cases discussion 12.30–13.30 Final Remarks Michael J Seckl, EOTTD, London, UK Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Adilia Urmanceeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Elena Bakhidze, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg Evgeniya Cyrlina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St.Petersburg 13.30–14.00 Discussion

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June, 20, Thursday | Hall Red 8+9 15.40–15.55 Androgen dependent signaling pathway and prostate cancer Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

June, 22, Saturday | Hall Red 10 12.05–12.25 Practical aspects of solid tumors immunotherapy Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

June, 22, Saturday | Hall Red 11 15.50–16.10 The present and the future of drug therapy for gastrointestinal tract neuroendocrine tumors Vera Gorbunova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

June, 20, Thursday | Hall Green 10 08.00–08.15 Cancer induced economic damage in Russia Anton Barchuk, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.20–08.35 Challenges for fight against cancer in Russia Aleksey Belyaev, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 08.40–08.55 Human papillomavirus spread in Russia Elena Ulrikh, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

June, 21, Friday | Hall Red 11 17.40–18.00 Recent achievements in targeted therapy of non-small cells lung cancer with activating mutations Sergey Orlov, ФГБНУ «НИИ МП», St. Petersburg

June, 23, Sunday | Hall Green 8 12.10–12.25 Clinical use of Digital PET: the future of molecular imaging Ignasio Carrio, University of Barcelona, Barcelona, Spain

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June, 21, Friday | Hall Blue 4+5 14.50–15.15 Selection of adjuvant systemic therapy of HER2+ breast cancer Irina Kolyadina

June, 21, Friday | Hall Blue 4+5 16.25–16.45 Prospects in metastatic triple negative breast cancer treatment Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

June, 22, Saturday | Hall Green 9 09.00–09.10 Thyroid cancer. Evolution of treatment. Modern vision of the treatment problem Zamira Radjabova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

09.15–09.30 Preparation for treatment with radioactive iodine of patients with highly differentiated thyroid cancer Pavel Rumyantsev, ФГБУ «Эндокринологический научный центр» Министерства здравоохранения Российской Федерации, Moscow

10.35–10.50 Drug treatment of medullary thyroid cancer Ilya Romanov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

June, 22, Saturday | Hall Red 11 14.30–14.55 Role of antiangiogenic therapy in gastrointestinal tumors treatment Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 15.00–15.20 New treatment strategies for metastatic pancreatic cancer Ilya Pokatayev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

June, 23, Sunday | Hall Blue 2 10.40–10.55 Early prescription of taxanes in metastatic prostate cancer in the section «A school for young oncourology doctors»: Prostate cancer diagnosi Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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Hall Blue 1

20, june, Symposium lunch thursday Launch of new opportunities in treatment 12.30–14.00 of patients with stage III NSCLC Chair: Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.30–12.35 Opening Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.35–12.55 Precise staging – the cornerstone in the treatment policy choice for Stage III NSCLC Evgeny Levchenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.55–13.15 Stage III unresectable NSCLC. How to maximum chemoradiotherapy efficacy? Natalia Dengina, State healthcare clinical oncology center, Ulyanovsk 13.15–13.35 Immunochemical radiation therapy for Stage III NSCLC. Start of new opportunities Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.35–13.55 Immunochemical radiation therapy introduction into clinical practice Dina Sakaeva, SBHI Republican clinical oncology center of Bashkortostan Ministry of Health, Ufa 13.55–14.00 Questions. Closing remarks

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Hall Blue 1

20, june, International event of the oncology thursday scientific scientific (OSE) 18.45–20.15 Prospects for recent achievements in HR + HER2 – advanced breast cancer treatment Moderator: «Prof. Fabrice André, Prof. Tatiana Semiglazova, Institut Gustave Roussy, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, France, Russia Medical judgment extend: What do the new possibilities of HR +, HER2-early breast cancer therapy open to us? Prof. Dr. Sybille Loibl, Johann Wolfgang Goethe University, Germany Introduction of biomarkers in the mandatory concept of treatment: current state Prof. Fabrice André, Institut Gustave Roussy, France Optimal treatment opportunities and life quality Prof. Dr. Sybille Loibl, Johann Wolfgang Goethe University, Germany Optimal treatment opportunities – A clinical event and discussion M.D., Prof Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Q&A session Moderator: Moderator: Prof. Fabrice André, Institut Gustave Roussy, France

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Hall Blue 2

20, june, Symposium lunch thursday «Residual tumor in HER2-positive breast 12.30–14.00 cancer: any chances for a cure?» (Not included in the CME program) Chairs: Alexander Petrovsky, Moscow Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Principles of neoadjuvant breast cancer therapy Mona Frolova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Clinical and prognostic value of residual tumor after neoadjuvant therapy Irina Kolyadina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow A pathologist’s opinion on a residual tumor Julia Andreeva, FSBEI for Additional Professional Education of Russian Medical Academy Continuous Professional Education under Ministry of Health of the Russian Federation, Moscow The changing paradigm of treatment for early HER2-positive breast cancer Lyudmila Zhukova, A.S. Loginov Moscow clinical scientific center, Moscow

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Hall Green 8

20, june, Symposium lunch thursday Melanoma 360°: an interdisciplinary ap- 12.30–14.00 proach to diagnosis and treatment (Not included in the CME program) Moderator: Nikolay Zhukov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunologyа, Moscow 12.30–12.45 About melanoma in a new light – urgency of the problem today Nikolay Zhukov, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunologyа, Moscow 360° – role of a multidisciplinary team 12.45–13.05 Interaction between a geneticist and a clinician Igor Samoylenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.05–13.25 Interaction between a surgeon and a chemotherapist Kirill Baryshnikov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Kristina Orlova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Drug therapy for melanoma from A to M 13.25–13.45 Adjuvant therapy for melanoma Kristina Orlova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.45–14.00 Unresectable melanoma Igor Samoylenko, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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Hall Red 8+9

20, june, Symposium lunch thursday Issues of hemostatic agents and suture ma- 12.30–14.00 terial use in urology (Not included in the CME program) Chairs: Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Sergey Petrov, Pavlov First St.Petersburg State Medical University First St.Petersburg State Medical University, St. Petersburg 12.30–13.15 Role of modern suture materials in endoscopic surgery Alexander Nosov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.15–14.00 Hemostatic agents and their use in endourology Sergey Petrov, Pavlov First St.Petersburg State Medical University First St.Petersburg State Medical University, St. Petersburg

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Hall Red 10

20, june, Symposium thursday Outpatient oncology 12.30–14.00 (Not included in the CME program) Chair: Boris Kasparov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.30–12.50 «Clinical guidelines for vascular access systems: European, Russian, American ones» Leonid Tsepenshchikov, CHVR Hopital de Sion, Sion, Switzerland 12.50–13.10 «Is a port system just a vascular access or something more?» Leonid Karev, «MEDSI» Clinical hospital, Moscow 13.10–13.25 «Prevention of complications of implantable venous access port systems» Mikhail Sherstnov, FSBHI Clinical Hospital №122 named after L.G. Sokolov, St. Petersburg 13.25–13.40 «Implantable port systems for peritoneal access. Application in outpatient oncology» Azam Khalikov, City clinical cancer center, St. Petersburg 13.40–13.55 «Treatment of pain syndromes in inoperable cancer patients» Sergey Koptsov, St. Petersburg City Hospital №40 under MoH RF, St. Petersburg 13.55–14.00 Discussion

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Hall Blue 2

21, june, Symposium lunch Friday HR + HER2 of advanced breast cancer 12.30–14.00 targeted therapy: whom, when and how (Not included in the CME program)

Moderator: Daniil Stroyakovskiy, Moscow city oncology hospital № 62, Moscow PI3K-Akt-mTOR in pathogenesis of breast cancer: an α-oncogenic driver Boris Zhivotovsky, Karolinska Institutet (Sweden), Lomonosov Moscow State University (Russia), Sweden, Russia SOLAR-1: Alpelisib + Fulvestrant during HR + HER2-early breast cancer therapy Dr Monica Arnedos, Institut Gustave Roussy, France Panel discussion of experts: «A patient comes to me...» When I will prescribe CDK4/6 inhibitors Daniil Stroyakovskiy, Moscow city oncology hospital № 62, Moscow When I will prescribe mTOR inhibitors Lyudmila Zhukova, A.S. Loginov Moscow clinical scientific center, Moscow Who are the patients with PIK3CA gene mutation? Mario Campone, Institut de Cancérologie de l’Ouest (ICO)

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Hall Blue 4+5

21, june, Symposium lunch Friday «Evolution of triple negative breast can- 12.30–14.00 cer therapy» (Not included in the CME program) Chairs: Alexander Petrovsky, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Peter Krivorotko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg ТCurrent clinical practice for metastatic triple negative breast cancer treatment Lyudmila Zhukova, A.S. Loginov Moscow clinical scientific center, Moscow Features of metastatic triple negative breast cancer clinical course Irina Kolyadina, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Background for immunotherapy in case of triple negative breast cancer Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Role of PD-L1 as a biomarker in breast cancer. What does a clinician need to know? Larisa Zavalishina, FSBEI for Additional Professional Education of Russian Medical Academy Continuous Professional Education under Ministry of Health of the Russian Federation, Moscow Place of immunotherapy in 1st line of treatment for patients with metastatic triple negative breast cancer Mona Frolova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

21, june, Friday 18.00–19.30

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Hall Green 8

21, june, Symposium Friday From clinical studies to practice: the 12.30–14.00 choice of optimal treatment for patients with luminous HER2-mRMZH

Chair: Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg 12.30–12.35 Opening Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg 12.35–12.50 We determine the algorithm for the treatment of patients with HR + HER2- mRMZH Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg 12.50–13.05 We evaluate the safety of treatment of patients with HR + HER2-mRMZH Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.05–13.45 Clinical Case Studies with Interactive Voting Moderators: Elena Slonimskaya, St. Petersburg City clinical oncology center, St. Petersburg Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.05–13.25 The choice of treatment in a patient with HR + HER2-mRMZH with concomitant cardiovascular pathology - analysis of a clinical case with interactive voting

Discussion: Elena Slonimskaya Mikhail Kurzhupov, SBHI « Clinical Diagnostic Center №4 of Moscow Health Department», Moscow 13.25–13.45 Selection of sequential treatment in a patient with HR + HER2-mRMG - analysis of a clinical case with interactive voting

Discussion: Rashida Orlova Elena Chernyakova, Republican Oncological Dispensary of the Ministry of Health of the Republic of Karelia, Petrozavodsk 13.45–14.00 Closing remarks Rashida Orlova, St. Petersburg City clinical oncology center, St. Petersburg

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Hall Red 9

21, june, Symposium Friday Immuno-oncology: modern capabilities of 12.30–14.00 therapy personalization (Not included in the CME program)

Chair: Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.30–12.50 Immuno-oncology: modern capabilities of therapy personalization Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.50–13.10 Value of the PD-L1 expression when choosing immunotherapy for NSCLC Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.10–13.40 Prognostic and predictive role of PD-L1 expression in urothelial carcinoma Sergey Petrov, Pavlov First St.Petersburg State Medical University First St.Petersburg State Medical University, St. Petersburg 13.40–14.00 Immunotherapy personalization for head and neck squamous cell carcinoma Svetlana Kutukova, St. Petersburg city cancer center, St. Petersburg

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Hall Red 10

21, june, Symposium lunch Friday General concept of adaptive therapy 12.30–14.00 development (Not included in the CME program)

Speaker: Yvette Wilbur Varian Medical Systems

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Hall Red 11

21, june, Symposium lunch Friday Drug therapy for breast cancer. From 12.30–14.00 generality to individuality (Not included in the CME program) Chair: Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.30–12.35 Opening Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.35–12.50 History of the breast cancer drug therapy development Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.50–13.15 Individualization of hormone-sensitive breast cancer therapy Maria Konstantinova, M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow 13.15–13.40 Is there room for new approaches to hormone-resistant breast cancer? Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.40–13.55 Breast cancer associated with BRCA mutations – a new subtype? A clinical event Nikita Volkov, St. Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological), St. Petersburg 13.55–14.00 Discussion. Closing remarks Vladimir Semiglazov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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Hall Blue 1

22, june, Symposium Saturday Breakthrough pain in cancer patients: 13.30–15.00 enchained by old paradigms or a new look into the future (Not included in the CME program) Chairs: Diana Nevzorova, SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow Sebastiano Mercadante, Pain management and palliative care center at the La Maddalena Cancer Center, Palermo, Italy 13.30–13.35 Opening Diana Nevzorova, Sebastiano Mercadante 13.35–13.55 Therapeutic approaches to breakthrough pains management in cancer patients: research data and skills of a physician in solution finding Sebastiano Mercadante, Pain management and palliative care center at the La Maddalena Cancer Center, Palermo, Italy 13.55–14.15 The state of the problem of breakthrough pain treatment for cancer patients in Russia Diana Nevzorova, SBHI «Palliative Care Center of Moscow Healthcare Department», Moscow 14.15–14.35 Breakthrough pain treatment algorithms in the framework of Russian clinical guidelines and the prospects for their development Gyuzel Abuzarova, Palliative care center for cancer patients in P.A. Hertsen – branch of FSBI NMRRC of the Ministry of Health of the Russian Federation, Moscow 14.35–14.55 Pharmacological points of the breakthrough pain therapy safety Alexander Sidorov, Department of Pharmacognosy and Pharmaceutical Technology, FSBEI HE Yaroslavl State Medical University of the Ministry of Health of Russia, Yaroslavl 14.55–15.00 Discussion

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Hall Blue 3

22, june, Symposium lunch Saturday Expected and possible changes in ad- 12.30–14.00 vanced ovarian cancer treatmen (Not included in the CME program) Chairs: Elena Ulrich, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Alexander Fedenko, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow Svetlana Khokhlova, FSBI Science center obstetrics, gynecology and perinatology named after academician V.I. Kulakov, Moscow 12.30–12.40 Opening. Ovarian cancer therapy historical points and current stage of development Alexander Fedenko, P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia, Moscow 12.40–13.00 Ovarian cancer with BRCA genes mutations: new therapeutic opportunities in the first stage of treatment Svetlana Khokhlova, FSBI Science center obstetrics, gynecology and perinatology named after academician V.I. Kulakov, Moscow 13.00–13.15 BRCA-associated ovarian cancer in the Russian population. Urgency of the issue Alexandra Tyulyandina, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.15–13.35 Issues of testing and genetic counselling for ovarian cancer patients Evgeny Imyanitov, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.35–13.50 Alternative approach to recurrent ovarian cancer treatment Ilya Pokatayev , FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.50–14.00 Discussion. Closing remarks. How ovarian cancer patients treatment algorithm may change in the nearest future Elena Ulrich, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg

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Hall Blue 5

22, june, Symposium lunch Saturday REACHING GOALS WE CHANGE LIFE of 12.30–14.00 a patient WITH HR + HER2-advanced breast cancer (Not included in the CME program) Breast cancer: the bare truth (opening motion picture) Please meet Alexandra and her story (a clinical event presentation) Olga Gordeeva, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow What type of therapy would you choose? (auditory voting) One life – three therapy options (speakers debates) Lyudmila Zhukova, SBHI A.S. Loginov Moscow clinical scientific center of Moscow Healthcare department, Moscow Irina Kolyadina, Russian Medical Academy of Continuous Professional Development, Moscow Dr. Michele De Laurentiis, UOC Oncologia Medica SenologicaI, RCCS Fondazione Pascale, Napoli, Italy Choice of an attending physician. Therapy results. Olga Gordeeva FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow New perspectives from the first person: New indications for the use of Ribociclib (Risarg), capability enhancement. Dr. Michele De Laurentiis, UOC Oncologia Medica SenologicaI, RCCS Fondazione Pascale, Napoli, Italy The first is EFFICIENCY with high quality of life. Results and conclusions.

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Hall Green 9

22, june, Symposium Saturday Sequential therapy for non-small cell lung 12.30–14.00 cancer (Not included in the CME program)

Chair: Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.30–12.40 Opening Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.40–13.15 The optimal sequence of EGFR-positive NSCLC targeted therapy Nir Peled, The Legacy Heritage Oncology Center & Dr. Larry Norton Institute, Soroka Medical Center & Ben-Gurion University, Beer-Sheva, Israel 13.15–13.35 Afatinib use features in real clinical experience Dina Sakaeva, «Republican Clinical Oncology Center of the Ministry of Health of the Republic of Bashkortostan», Ufa 13.35–13.55 New features of NSCLC treatment sequence without driver mutations Alexey Smolin, FSBI «Main military clinical hospital named after academician N.N. Burdenko» unde the Ministry of defense of the Russian Federation, Moscow 13.55–14.00 Closing address Konstantin Laktionov, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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Hall Red 10

22, june, Symposium lunch Saturday «FROM THEORY TO PRACTICE WAS A 12.30–14.00 SUCCESS...» (Not included in the CME program)

Chairs: Rashida Orlova, St. Petersburg city clinical cancer center, St. Petersburg State University, St. Petersburg Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg Svetlana Protsenko, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.30–12.50 Expansion of therapy opportunities for disseminated gastric cancer Tatiana Semiglazova, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 12.50–13.20 «Achievements in the disseminated gastric cancer treatment in real clinical experience Results of the ramucirumab use expanded access program of in St. Petersburg» Rashida Orlova, St. Petersburg city clinical cancer center, St. Petersburg State University, St. Petersburg 13.20–13.40 Is it possible to achieve a complete and prolonged tumor regression in a disseminated gastric cancer patient? Gulfiya Teletaeva, FSBI «N.N. Petrov NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, St. Petersburg 13.40–14.00 Q&A session

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Hall Red 11

22, june, Symposium lunch Saturday Role of a multidisciplinary approach in 12.30–14.00 metastatic colorectal cancer treatment (Not included in the CME program) Chairs: Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Rashida Orlova, St. Petersburg University, St. Petersburg State Budgetary Healthcare Institution «CIty clinical cancer center», St. Petersburg 12.30–12.50 Role of a multidisciplinary team in treating patients with mCRC Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 12.50–13.10 Experience of cetuximab use in the mCRC frontline of as part of a clinical study Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow 13.10–14.00 A case conference: interactive analysis of clinical events with mCRC patients treatment Vyacheslav Aliev, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Elena Artamonova, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow Konstantin Mamontov, RSHI Altai Regional Oncology Center, Barnaul Mikhail Fedyanin, FSBI «N.N. Blokhin NMRC of oncology» of the Ministry of Healthcare of the Russian Federation, Moscow

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