2Nd Faculty of Medicine - English Division

Medical University of Warsaw 2nd Faculty of Medicine - English Division 61 Żwirki i Wigury Street 02-091 Warsaw Phone: + 48 (22) 5720 502 Fax:+48 (22) 5720 562

e-mail: [email protected] http: www.wum.edu.pl

1st YEAR CURRICULUM 4-year program

Warsaw, 2010/2011 CLINICAL ANATOMY Department of Anatomy Centre of Biostructure Research Address: 5 Chałubińskiego St. 02-004 Warsaw, Poland tel./fax +48226295283 http://www.ib.amwaw.edu.pl/anatomy

Head: Prof. Bogdan Ciszek, MD, PhD.

Curricular affairs: Adam Koleśnik, M.D.

Number of teaching hours: lectures - 54 hrs seminar - 40 hrs practical classes - 160 hrs

Assessment of student performance: On completion of the course student are expected to take final examination, which consist of two parts: practical (PIN test) and theoretical (MCQ test).

The aim of the course: Is to teach students fundamental anatomical knowledge with strong emphasis on clinical aspects and radiological anatomy (eg. X-ray, CT, MRI).

Topics of lectures

OSTEOLOGY Introduction to the Gross and Clinical Anatomy. Anatomy for the vertebral collumn. Anatomy of the joints. Development and general structure of the skull. The spaces of the skull and their communication. Foramina, canales and fossae cranii. Temporal bone. Radiological anatomy of the bones and joints. MRI and CT anatomy of the bones and joints.

CENTRAL NERVOUS SYSTEM Classification of the central nervous system. Development of the central nervous system. Cerebro- spinal fluid and ventricular system of the brain. Cerebral hemisphere. Frontal, parietal, temporal, occipital, limbic lobes. Anatomy of gyri and sulci. Lateral and third ventricle, basal nuclei, diencephalon. Brain stem, cranial nerves, cerebellum. Sensory pathways and centers in the central nervous system. Motor pathways of the central nervous system. Anatomical base for MRI, CT and angiography of the brain and spinal cord. Vascularization of the central nervous system. Clinical microanatomy. HEAD AND NECK General topography of the neck. Cervical plexus. Triangles of the neck. Interfascial spaces. Arteries, veins, lymphatic system of the neck. Thyroid gland, parathyroid glands. Larynx - topography, structure, vascularization, innervation. Facial nerve. Trigeminal nerve, parasymphathetic ganglia of the head. Autonomic system of head and neck. Vagus nerve, glossopharyngeal nerve, symphathetic trunk. Nasal cavity, paranasal sinuses. Oral cavity, soft palate, pharynx. Visual system, optic pathway. Middle ear and vestibulo-cochlear system. Head and neck - X-ray, CT, MRI images.

THORAX The thoracic wall and the thoracic cavity. Congenital and acquired defects of the thoracic wall. Vessels and nerves of the thoracic wall. Mammary gland (breast) and lymphatic drainage. Development of the trachea, bronchi and lungs. The lungs and the pleura. The respiratory cycle. Mediastinum. Topography and subdivisions. The heart. Vessels and nerves of the heart. Development of the heart. Cardiac malformations. Applied anatomy. X-ray, CT and MR imaging of the thoracic cage.

ABDOMEN Abdomen, abdominal cavity, walls of the abdominal cavity, inguinal canal, inguinal hernia. Development of the peritoneal cavity and alimentary tract. Structure and topography of the liver, bile ducts and pancreas. Vascularization of the abdominal organs, vena portae. Lymphatic system of the abdominal cavity. Innervation of the abdominal cavity. Coeliac plexus. Radiological anatomy of the abdomen.

GENITOURINARY SYSTEM Retroperitoneal space and its contents. Urinary system. Male reproductive system. Female reproductive system. Floor of the pelvis (diaphragms, interfascial spaces, fossea and canales) Perineum - applied anatomy. Perineum - applied anatomy. Urogenital system in X-ray, CT, MR and USG.

BACK AND UPPER EXTREMITY The development of the locomotory apparatus. Topographical and practical anatomy of the back. Topography of the pectoral girdle. Topography of the arm and forearm. The hand - practical and topographical anatomy. Syndromes of the nerve and vascular injury to the hand. X-ray, MRI of the upper extremity.

LOWER EXTREMITY General topography of the pelvic girdle, thigh, leg and foot. Surgical spaces of the lower extremity. Vascularization and innervation of the lower extremity. X-ray, MRI, CT, arteriography of the lower extremity. Topics of practical classes and seminars OSTEOLOGY Lab session 1 Vertebral column, thorax. Lab session 2 Upper limb and its girdle. Lab session 3 Lower limb and its girdle. Lab session 4 Skull – part one. Lab session 5 Skull – part two.

Seminar 1 Radiologic anatomy of the skeleton. Seminar 2 Clinical examination of bones and joints.

CENTRAL NERVOUS SYSTEM Lab session 1 General anatomy of the central nervous system. Lab session 2 Encephalon. Lab session 3 Ventricular system of the brain, diencephalon. Lab session 4 Brain stem, cerebellum. Lab session 4 Motor and sensory pathways.

Seminar 1 CT and NMR imaging of central nervous system. Seminar 2 Clinical examination and functional anatomy of the central nervous system.

HEAD AND NECK Lab session 1 Muscles and vessels of the neck. Lab session 2 Viscera of the neck. Lab session 3 Muscles of facial expression (vascularization, innervation). Lab session 4 Viscera of the head. Lab session 5 Eyeball and orbit. Lab session 6 Ear and temporal bone.

Seminar 1 Anatomical basis for clinical examination of the eye. Seminar 2 Anatomical basis for clinical examination of the ear.

THORAX Lab session 1 Walls of thorax, axillary fossa, brachial plexus, mammary gland. Lab session 2 Mediastinum. Lab session 3 Esophagus, aorta and its branches, autonomic nervous system of the thorax. Lab session 4 Lungs, bronchial tree. Lab session 5 Heart.

Seminar 1 Anatomical basis for examination of the heart and circulatory system. Seminar 2 Radiological anatomy of the thorax.

REPETITIONS Lab session 1 Repetition – osteology. Lab session 2 Repetition - central nervous system. Lab session 3 Repetition - head and neck. Lab session 4 Repetition – thorax. ABDOMEN Lab session 1 Abdominal wall, inguinal canal. Lab session 2 Topography of peritoneal cavity. Lab session 3 Liver, spleen, pancreas. Lab session 4 Large intestine, small intestine. Lab session 5 Radiological anatomy of the abdomen.

Seminar 1 Ultrasound imaging of the abdomen. Seminar 2 Anatomical basis for examination of the abdomen.

GENITO-URINARY SYSTEM Lab session 1 Retroperitoneal space. Lab session 2 Female genital organs. Lab session 3 Male genital organs. Lab session 4 Floor of pelvis, perineum, diaphragm of pelvis, urogenital diaphragm. Lab session 5 Radiological anatomy of the retroperitoneal space and pelvis.

Seminar 1 Clinical anatomy in gynecology. Seminar 2 Clinical anatomy in urology.

BACK AND UPPER EXTREMITY Lab session 1 The back. Lab session 2 Upper extremity girdle, arm. Lab session 3 The forearm. Lab session 4 The hand. Lab session 5 Anatomical basis for arthroscopy of the shoulder joint.

Seminar 1 Anatomical basis for examination of the hand and surgical treatment of hand injures.

LOWER EXTREMITY Lab session 1 Pelvic girdle, hip joint. Lab session 2 Thigh, knee joint. Lab session 3 Leg, foot. Lab session 4 Anatomical basis for arthroscopy of the knee joint. Seminar 1 Anatomical basis for treatment of peripheral vascular disease of lower extremity.

Basic textbooks: 1. Grey’s Anatomy 2. Anatomy, A.W. Rogers 3. Synopsis of Gross Anatomy, Christensen

Complementary textbooks: 1. Sobbota Atlas of Anatomy 2. Atlas of Anatomy, Yokoshi/Rohen 3. Atlas of Anatomy, McMinn 4. Terminologia Anatomica, Thieme 1998 5. Latin-English Anatomical Dictionary, Aleksandrowicz, PZWL 1997 INTERNAL REGULATIONS OF THE DEPARTMENT OF ANATOMY

1. In order to complete a semester, a year and to pass Fianl Anatomy Examination student should participate actively in lectures and practical classes and obtain at least satisfactory grade after each practical classes and credits. CAUTION: During the course of anatomy, the student is supposed to have the knowledge acquired from all previous practical classes. 2. The course of anatomy is divided into eight following parts: (a) bones, joints and ligaments, (b) central nervous system, (c) neck, head and sensual organs, (d) thorax, (e) abdomen, (f) perineum and urogenital organs, (g) upper limb and back, (h) lower limb. Immediately after the last practical classes of each part credit will be administered (first term). Retake of the failed credit (second term) follows during next two practical classes and a teaching assistant organizes it. Third attempt of the credit (commissionary retake) is organized at the end of the second semester (second half of May) after the completing of the entire anatomy course. Two examiners without participation of teaching assistant administer the commissionary retake of the failed credit. 3. After each semester follows the practical intermediate (semestral PIN-test), which is not obligatory but highly, recommended as a preparation to the final practical exam. Only student who wants to receive early term (zero term) of Final Anatomy Exam have to complete each semestral PIN-test with the score of 100 points or more (max. possible -120 points). 4. Absence exceeding two practical classes of one part (caused by objective reasons) excludes receiving a credit. Absence exceeding two practical classes per one part or four practical classes per semester excludes receiving a credit and student has a chance of completing this credit on the commissionary retake only (second half of May). 5. If an absence was caused by objective reasons (i.e. health problems with medical evidence) student can move a term of credit to next practical class after scheduled one. 6. The Final Anatomy Examination is scheduled in summer examination period and consists of two parts: practical (PIN-test) and theoretical (Multiple Choice Questions test). In order to pass the exam, the student should pass two parts with at least satisfactory grades. The level to pass practical exam is 76/120. The level to pass MCQ is 76/120. Examination grades according to points: 152-169 – satisfactory, 170-187 – more than satisfactory, 188-205 – good, 206-223 – more than good, 224-240 – very good. 7. Retake of the Final Anatomy Examination is administered in September. Students who passed only the practical part of the Final Anatomy Examination during first term have to retake the failed theoretical component only. 8. Students who completed all 8 credits with the grade 4 and more and received more then 100 points from both semestral PIN-tests can be examined in special early term of exam by the head of department. 9. Practical anatomy involves students in the examination and dissection of human subjects. This privileged opportunity relies on the generosity of local people who recognise the value to medicine that the practical study of human anatomy can provide and generously make their bodies available for that purpose to medical and science students. It is important that, at all times, you respect that generosity and behave accordingly. 10. Much of the course work is carried out in the Dissection Room. To enter it students will need to provide themselves with clean white lab coats, white protective hat and photo ID badge. Changing of the clothes should be done outside the Dissection Rooms only. Students are allowed to enter the Dissection Room only in time of practical classes of his students‘ group if not otherwise specified. 11. Unauthorized persons may not enter the Dissection Rooms. 12. Students MUST care about hygiene. In particular:  have clean hands with short unpolished nails; no jewellery is allowed,  use protective gloves while examining of specimens,  in the case of minor injuries rinse the wound in tap water and manage it properly. 14. While examining the specimens, sufficient care should be applied to prevent the damage or loss of the specimen. 15. Leaders of the student’s groups are responsible for damage or loss of the specimen. 16. Smoking in the area of the Department of Anatomy, as in whole building of Collegium Anatomicum, is prohibited. 17. Eating and drinking in Dissection Rooms is not allowed. 18. The students can, and are encouraged, to bring the anatomical tweezers, lancets, books and atlases to the Dissection Rooms. 19. To gain from the practical classes as much as possible, the students should have sufficient theoretical knowledge about the current topic. 20. At the end of practical classes students should fix the specimens according to the teaching assistant suggestions. 21. Taking of any photo or movie in dissection room is strictly prohibited! 22. It is not allowed to use mobile phones in the area of the Department of Anatomy! BIOPHYSICS Department of Biophysics Address:5 Chałubińskiego Street., 02-004 Warsaw Phone/fax: 022 628 78 46, 022 628 63 34 Head: Prof. Jacek Przybylski MD, PhD. Lecturers: Prof. Zbigniew Dunajski, MD, PhD, Prof. Jacek Przybylski M.D., PhD.

Number of teaching hours 30

Aim of the course: To provide a foundation for the further pursuit of biophysical knowledge both in theory and in practice. The course aims to provide a foundation for the development of clinical research and learn more about Medical Physics and imaging science in general. The course aims to present the subject with physical science content whilst still being of great practical relevance.

Assessment of student performance: To impart knowledge and understanding of electrophysiological signal evolution, characteristics, propagation and imaging. To give students a basic understanding of what goes on inside the various pieces of diagnostic and therapy equipment. Understanding of electrodes, potential distribution, electrical stimulation and signal processing. To impart knowledge on the imaging techniques and the processes involved in the generation of useful images, understanding on the basic physical principles of Magnetic Resonance Imaging and Ultrasound Imaging. To impart knowledge and understanding of ionising radiation, detection and medical ionising radiation imaging.

Topics of lectures:

1. Electric potential, field, current, conductivity and impedance, magnetic field, basic laws of electromagnetism. Electric properties of living tissue. (4h) 2. The current, potentials and magnetic field distributions within the body. Dipolar models of the bioelectric sources and their imaging and localization. (4h) 3. Electromagnetic fields in the conducting tissue: electromagnetic spectrum, interaction of electromagnetic fields with living matter, thermal effects - SAR, electric and magnetic stimulation. (4h) 4. Nuclear magnetic resonance and their application in imaging of the tissue structure -MRI, functional MRI, spectroscopy. (2h) 5. Measurements of biological signals, signal processing and characterisation: sensors, amplifiers, A/D converters, filters and analysis. (2h) 6. Visible light and optics. Principles of light-guides. Lasers - principles, examples of applications. Ultraviolet light. Definition of ionizing radiation. (2 h) 7. X-rays. X-ray interactions with matter - absorption and scattering. Ionization of matter by secondary electrons. Sources of radiation - alpha and beta decay, gamma radiation. Radioactive decay law (2 h) 8. Radiation protection and dosimetry: Definition of absorbed dose. Biological effects of radiation. Risk factors. Equivalent dose in an organ or tissue. Effective dose. Ambient dose equivalent. Natural radiation background. Ionization chambers and Geiger-Müller counters (2 h) 9. Force and stress in rigid bodies and in liquids, vectors, moments, work. (2h) 10. Fundamental mechanical properties of biological tissues: Compressible and incompressible liquids and their main properties, perfect gas and real gases, dependence between density and pressure, dynamic and kinematic viscosity coefficient, rheological parameters of blood as a certain non-Newtonian liquid, viscosity of blood. (2 h) 11. Basic features and parameters of flow: Laminar and turbulent flows, velocity and pressure fields, hydrostatic pressure, Bernoulli equation, Hagen-Poiseuille’s law, volume flow rate, average velocity, Reynolds number, hydraulic resistance to flow of a vascular segment, concept of wall shear and normal stress, influence of vascular shape on resistance to flow, properties of a vascular tree – the principle of minimum work of biological system,. (4 h). 12. Sound, ultrasound, wave propagation in leaving tissue, Doppler’s phenomenon and its application to blood velocity measurements in arterial segments, (2h).

Literature: P. Davidovic Physics in Biology and Medicine Elsevier 2001 R.K. Hobbie Physics for medicine & biology Springer Verlag, 1997 B. H. Brow, et al., Medical Physics and Biomedical Engineering. IOP Publishing S.C. Bushong, Radiologic Science for Technologists, Physics, Biology and Protection, Mosby, 1997 Printed course lectures are foreseen.

Examination procedure: The assessment will consist of 1 oral check PHYSIOLOGY Chair and Department of Experimental and Clinical Physiology Address: 26/28 Krakowskie Przedmieście Street, 00-325 Warsaw, www.am.edu.pl/physiology phone: 022 826 07 78

Head: Prof. Ewa Szczepańska-Sadowska, MD, Ph.D.

Curricular affairs: Ewa Koźniewska, MSc., PhD. [email protected] phone:: 022 608 64 89 or through the Dean Office

Number of hours: 110 105.5 hrs of lectures 4.5 hrs of intermediate examinations (1.5 hr each)

The aim of the course: The objective of teaching is to acquaint the students with the mechanisms responsible for normal function of the human body and give them the physiological basis for prophylaxis, diagnosis, treatment and rehabilitation.

Assessment of student performance: Knowledge of physiology is assessed 3 times during the course in a form of intermediate MCQ examinations on completion of the respective part of physiology (neurophysiology; circulatory and respiratory physiology; kidney, gastrointestinal, hormones and applied physiology). On completion of the course students are expected to take a final MCQ examination. To become eligible for the final examination student has to obtain credit for each of the intermediates.

Basic textbooks: 1. Guyton AC, Hall JE. Textbook of Medical Physiology, 11th edition, 2005, W.B. Saunder’s Co., Philadelphia. 2. Berne M., Levy M.N., Koeppchen B.M., Stanton B.A. Physiology, 5th edition, 2004, Mosby Co.

Complementary textbooks: 1. Kandel E, Schwartz JH, Jessell TM. Principles of Neural Science. 4th edition, 2000, Elsevier, New York. 2. Willmore JH , Costill DL. Physiology of Sport and Exercise, 1999, Human Kinetics. MEDICAL PARASITOLOGY Department of Medical Biology, Address: 73 Nowogrodzka Street., 02-018 Warsaw Phone: 022 625 24 68

Head: Prof. Lidia Chomicz, MD, PhD

Curricular affairs: Prof. Lidia Chomicz, MD, PhD

Number of teaching hours: lectures - 10 hrs practical classes - 20 hrs

The course is offered at the beginning of the winter (I) semester (commencement and schedule- see the time-table of the study given by Dean of the English Division and presented on the board in the Department of Medical Biology, 73 Nowogrodzka Street). Lectures and laboratory classes will be held in the Department of Medical Biology, 73 Nowogrodzka Street.

Assessment of student performance: On completion of the course of the Medical Parasitology students are expected to take a final assessment test. Students are assessed on the ground of regular attendance, activity during the classes as well as at least satisfactory grade on the final test. Successful completion of the course should be assessed and final grade and credit certified with a signature by the supervisor.

The aim of the course The Medical Parasitology integrated course offers to students the basic knowledge on selected aspects of biology and morphophysiology of different developmental forms of the medically important species belonging to Protozoa, Trematoda, Cestoda, Nematoda, Acarina and Insecta, colonizing human, tissues, organs and systems as well as on pathogenesis of diseases they cause. On completion of the course students should possess suitable knowledge on: - the main sources, routes and modes by which the parasites enter the human organism, - environmental factors decisive for a spread of parasites between people and animal hosts in different regions of the World, - the main zoonoses, - interrelation between immunological status of the human organism and course of parasitic disease particularly caused by opportunistic species, - role which may play arthropods in the pathogenesis and epidemiology of human diseases as parasites and vectors of parasitic, bacterial and viral pathogens. The students are also expected to know the principles of the differential diagnosis important for correct treatment, as well as useful measures to prevent the parasitic infections.

Topics of lectures 1. General information: medically - important species of parasites, facultative parasites and commensals; important terms. Types of changes in parasitic infections. Protozoa infecting the human alimentary tract: sources of infection, infective stages, routes of infection. 2. Transmission of the protozoan parasites. Parasitic and free - living Protozoa - facultative human parasites - infecting the human systems and tissues in Poland and in the World. 3. The opportunistic species: foundation of pathogenesis. Prevention in protozoan infections. 4. The medically - important Trematoda and Cestoda. The intestinal forms of Cestoda parasitizing humans. The spread of trematodes in the World.. 5. The main zoonoses – the infective stages, the sources and routes of infection; the preventive measures. Tissue forms of Cestoda parasitizing humans. 6. The main medically important parasitic Nematoda in Poland and World. Larva migrans visceralis; larva migrans cutaneus. Microfilariae. Measures of prevention. 7. The main factors influencing the spread of parasites. Animal and environmental reservoirs of the parasites. 8. Medically - important Insects and Arachnids - temporary and permanent human parasites; infective stages, sources, routes and the symptoms of infections. Role other arthropods in transmission of pathogens. 9. The parasites and vectors parasitizing people in Poland and World and their significance in epidemics. Tropical parasitic species. 10. The basic principles and methods of the differential diagnosis and prevention of the parasitic diseases.

During laboratory classes students are expected to examine macroscopic and microscopic preparations of various developmental stages of parasites, and damaged tissues and organs, according to a list of preparations. The self-instructional study guide students is given in the “ Medical Parasitology Student’s Workbook” edited by The Medical University of Warsaw, 2009. Students have to keep the documentation of their laboratory work in this book (part 1, 2 and 3). During classes students are expected to follow specific safety precautions i.e. white coats exclusively worn for classes are not to be used in the hospital wards. Current events concerning student performance and work are displayed on the Departments' board, in the Department of Medical Biology, 73 Nowogrodzka St..

Topics of practical classes

Unit 1 Selected parasitic and commensalic Protozoa of the human alimentary tract i.e. Giardia intestinalis, Entamoeba histolytica/ dispar, E. coli, Iodamoeba bütschlii -trophozoites and cysts. Giardiosis, amoebosis. Prevention. Opportunistic species e.g. Toxoplasma gondii, Cryptosporidium parvum, Pneumocystis carinii and a role of immunological competence of the host for development of the opportunistic disease. Unit 2 Parasitic Protozoa of the human oral cavity: Entamoeba gingivalis, Trichomonas tenax. Facultative human parasites: Acanthamoeba sp., Naegleria - their frophozoites and cysts as etiological factors of serious human diseases. Protozoa of the urogenital tract e.g. Trichomonas vaginalis. Effect of different environmental factors on viability of Trichomonas vaginalis. Mixed infections with Trichomonas vaginalis and fungi; transmission and preventive measures. Unit 3 Tissue-dwelling Protozoa: Trypanosomatidae e.g. Trypanosoma gambiense, T. cruzi, Leishmania tropica, L.donovani; malarian sporozoans: Plasmodium vivax, P. falciparum; other sporozoans: Babesia sp.. Unit 4 Selected intestinal, liver and blood Trematodes: Fasciolopsis buski, Fasciola hepatica, Opisthorchis felineus, Paragonimus westermani, Schistosoma haematobium, S. mansoni, S. japonicum. Sources of infection, infective stages, routes of infection. Unit 5 Intestinal forms of Cestodes: Diphyllobothrium latum, Taenia saginata, T.solium, Hymenolepis (Vampiriolepis) nana parasitizing human organism. Unit 6 The tissue forms of Cestodes parasitizing in man: T. solium, Echinococcus granulosus, E. multilocularis; zoonoses they cause: cysticercosis, cystic and alveolar echinococcoses. Unit 7 Parasitic Nematodes: Ascaris lumbricoides, Toxocara sp., Enterobius vermicularis, Trichocephalus trichiuris, Trichinella spiralis, Ancylostoma duodenale, Necator americanus , Strongyloides stercoralis, Wuchereria bancrofti, Loa loa, Onchocerca volvulus, Anisakis sp.. Unit 8 Parasitic arthropods - Insects: Pediculus humanus, Phthirus pubis, Cimex lectularius, Pulex irritans, Culex pipiens, Anopheles macullipennis, Simulium sp., Triatoma sp.. Unit 9 Parasitic arthropods - Arachnids: Ixodes ricinus, Argas reflexus, Sarcoptes scabiei. Arthropod - transmitted diseases; a significance of Insects and Arachnids as hosts or vectors in transmission of etiological agents of serious human diseases e.g. onchocercosis, wuchereriosis (elephantiasis), Lyme arthritis, viral encephalitis, babesiosis. Unit 10 Detection and identification of the most important parasites in different human tissues, organs and systems. Difficulties, mistakes and advances in the differential diagnosis of parasitic infections.

Basic textbooks: 1. F. A. Neva, H. W. Brown : Basic Clinical Parasitology. Prentice - Hall International Inc. 1994. 2. Lidia Chomicz: Guide to Medical Parasitology. New compendium for the medical students. Medical University of Warsaw, 2006. Medical parasitology student’s workbooks: L. Chomicz, A. Naprawska, J. Chomicz. Medical parasitology student’s workbook part 1. Oficyna Wydawnicza WUM 2009 L. Chomicz, J. Chomicz, D. Młocicki. Medical parasitology student’s workbook part 2 Oficyna Wydawnicza WUM 2009 L. Chomicz, G. Olędzka, J. Chomicz, Medical parasitology student’s workbook part 3 Oficyna Wydawnicza WUM 2009

Complementary textbooks: 1. M. Katz, D. D. Despommier, R. Gwadz: Parasitic Diseases. Springer - Verlag 1994. 2. W. Peters, G. Pasvol: Tropical Medicine and Parasitology (5th ed.). Mosby 2002 3. L. S. Garcia: Diagnostic Medical Parasitology. ASM -Press 2001. 4. Z. Pawłowski, J. Stefaniak (red): Parazytologia Kliniczna w ujęciu wielodyscyplinarnym. PZWL Warszawa, 2004. BIOCHEMISTRY Chair and Department of Biochemistry Address: 1.Banacha Street, 02-091 Warsaw Phone:. (48-22) 572 06 93 Head: Prof. Anna Barańczyk-Kuźma, M.D, Ph.D.

Person responsible for teaching: Prof. Anna Barańczyk-Kuźma, M.D, Ph.D.

Web site of Department of Biochemistry: biochemia.wum.edu.pl

Number of teaching hours: 120 Winter semester: total: 78 h : lectures: 32 h, seminars: 15 h, lab. classes: 15 h Spring semester: total 42 h: lectures: 28 h, seminars: 15 h, lab. classes: 15 h

Assessment of student performance: On completion of the course students are expected to take the final examination (MCQ test). Aim of the course: knowledge of macromolecules structure, biosynthesis and degradation, regulation and integration of metabolic pathways.

Winter semester Topics of lectures: 1 – 2. Protein structures and functions 3 - 8. Enzymes, Tissue oxidation, Citric acid cycle, Generation of ATP from glucose and fatty acids 9 - 13. DNA & RNA structure, DNA replication & mutations, Transcription, Protein biosynthesis, Regulation of gene expression. 14 - 16. Lipids metabolism, lipidoses and atherosclerosis

Topics of laboratory classes 1. Proteins 2. Enzymes 3. Lipids

Topics of seminars 1. Proteins 2. Enzymes 3. Tissue oxidation, citric acid cycle 4. Nucleic acids, DNA replication 5. Transcription, translation 6. Metabolism of lipids Assessment test at the end of winter semester.

Spring semester Topics of lectures 17-19. Carbohydrates metabolism 20. Digestion 21 – 23. Protein turnover, ureogenesis, Amino acids degradation 24 – 25. Blood: functions and constituents, gas transport 26. Nucleotide metabolism 27. Vitamins 28. Hormones 29. Biotransformation. Metabolism of xenobiotics. 30. Ethanol metabolism.

Seminars: 1. Carbohydrates I 2. Carbohydrates II 3. Ureogenesis, amino acids metabolism 4. Catabolism of amino acids 5. Blood 6. Liver metabolism and biotransformation

Laboratory classes 1. Digestive enzymes 2. Constituents of blood 3. Constituents of urine

Assessment tests at the end of spring semester.

Basic textbooks: 1. R.K.Murray, D.K.Granner, P.A.Mayers, V.W.Rodwell, Harpers’ Biochemistry, last edition, Appleton & Lange. 2. L.Stryer, Biochemistry, last edition, W.H.Freeman & Company, New York. 3. P.C.Champe, R.A.Harvey, Lippincott’s Illustrated Reviews: Biochemistry, I.B.Lippincott, Company, Philadelphia. 4. G.Meisenberg, W.H. Simmons, Principles of Medical Biochemistry, Elsevier, 2nd Edition 2006 (online access + interactive extras, studentconsult.com). 5. J.W.Baynes, M.H.Dominiczak, Medical Biochemistry, Elsevier, 3rd Edition 2009, (online access + interactive extras, studentconsult.com).

Complementary textbooks: 1. T.M.Devlin, Textbook of Biochemistry with clinical correlations, last edition, Willey- Liss,Inc. HISTOLOGY Chair & Department of Histology and Embryology, Centre for Biostructure Research Address: 5 Chałubińskiego Street (Anatomicum) 02-004 Warsaw e-mail address: histologia.wum.edu.pl Phone/fax 022 629 52 82; Head: Prof. Jacek Malejczyk, Ph.D. Curricular affairs: Prof. Jacek Malejczyk, MD, PhD - phone 022 629 52 82, 022 622 00 29

Number of teaching hours: course covers 98 hours of instruction, divided as below:  lectures: 27 hrs  practical classes: 71 hours

Assessment of student performance: On completion of the course students are expected to take final examination consisting of practical and written part. Practical final examination tests students’ ability to recognize slides demonstrated during practical classes. Written final examination (MCQ test) includes general histology and microscopic anatomy. The aim of the course: Students will get acquainted with the structure of cells, their organization into tissues and microscopic structure of organs. In addition to that, function of particular cellular structures visible under light and electron microscope and the relationship between function and structure of cells and tissues will be presented. This course constitutes a basis for cytophysiology, physiology, biochemistry and histopathology. Objectives of Histology teaching are achieved when students: - get familiar with the structure and function of cells, tissues and organs on the level corresponding to the scope of internationally recognized textbooks, - are able to recognize under the microscope structures of cells and tissues as well as organs of human body.

General regulations The course including lectures and practical classes consists of 2 parts: • general histology • microscopic anatomy At the end of each section students have to pass a respective intermediate exam. Passing both intermediate exams is required to get a full credit and to be qualified to take the final examination. Students should read respective chapters in the textbook(s) before practical classes. Students have to participate in discussion during practical classes and follow instructions of their professors. These include inspection of histological slides and drawing them with colour pencils in students’ notebooks, indicating names of the histological structures on these drawings. Class is dismissed when professor checked and approved the notes of students. No more than 2 absences are allowed during each part of the course, irrespective of the cause (justified or unjustified absence). Students who missed more than 2 classes will not be allowed to take the intermediate exam and, consequently, will not get a credit. Students should be aware that coming late to the class can be considered as absence. There are 2 intermediate (mid-term) examinations during the course and one final examination at the end of the semester. Each exam consists of practical (slide recognition) and written part. Both parts need to be passed since there is one note given for both of them. Practical part of the examination will test the ability of the student to recognize histological slides demonstrated in the course. The minimal score required to pass this part of the exam is 60% i.e. 3 slides out of 5 must be recognized to pass the intermediate exam and 6 slides out to 10 to pass the final exam. If the practical and written tests are passed on the first date (and only then!), extra points awarded for the practical test are added to the score obtained in the written part, which can affect the grade (see below). It is therefore highly recommended to prepare to both parts of the test simultaneously. Written examinations, intermediate and final, will be given in the MCQ format. Topics covered by test questions include only issues discussed in the recommended textbook and in the lectures. Written intermediate examinations and their first retakes consist of 30 questions in MCQ format. Each question is scored 1 point. Up to 2 points can be added for the practical part of the exam (if both passed on the first date). The minimal score required to pass the intermediate exam is 18. The form of the second retake of the intermediate examination is to be decided by the Head of the Department. Each intermediate exam can be taken up to 3 times. The date of each attempt will be fixed in advance after consulting the Dean’s Office. Practical part of each intermediate exam must be passed not later, than by the day of the first retake of the written part. Otherwise, the entire intermediate examination is considered to be failed. Final examination in Histology consists of 100 MCQ questions. Up to 4 additional points can be added for the practical part of the exam. The minimal score required to pass the exam is 60 points. Final examination will be is scheduled in the examination session in January, the retake in February. The dates of these examinations are appointed by the Dean’s Office and are not subjects of change.

Exemption from the examination: Students who were performing exceptionally well during both semesters can be exempt from the final examination in Histology. To be eligible to apply for the exemption student must have an average score at least of 4,25 and each intermediate exam score must be at least “good” (4,0). In addition to that all intermediate examinations including their practical parts must be passed on the first date. The Chair will make the decision on the exemption based on the scores and a recommendation from the tutor of the applicant.

Department’s policy regarding cheating on examinations Cheating on examinations is unethical and violates University law. Individuals who actively or passively participate in this activity will be removed from the examination and fail the exam. Active cheating includes copying answers given by other students or using illegal notes or electronic devices that can be used for communication or data storage. In general no electronic devices are allowed during examination in our Department. Examples of passive cheating include giving answers to other students during test or facilitating the act of cheating by other means (such as unjustified displaying of the answers to others). Therefore Students should take all precautions to prevent an occurrence of such situation. Chair of the Department obliges examiners and examinees to exercise this policy rigorously. Lectures: Part I (General Histology) 1. General structure of cells. Cell membranes, transport across cell membranes; 1. Cytoskeleton, ER (rough and smooth), Golgi system, endosomes, lysosomes, proteasomes, intracellular traffic; 2. Endocytosis, phagocytosis, caveolae, potocytosis, peroxisomes, mitochondria; 3. Nucleus, nucleolus, general introduction to cell cycle, cell division; 4. Epithelial tissue, intercellular junctions: types and function; 5. Connective tissue proper I; 6. Connective tissue proper II, adipose tissue; 7. Cartilage and bone, bone formation; 8. Hormones derived from cell membranes, defensins; 9. Nerve tissue. 10. Muscle cells, the types and their function; 11. Blood and bone marrow; 12. Blood and lymphatic vessels and heart; 13. General characterization of growth factors and cytokines Part II (Microscopic Anatomy) 1. Structure of female reproductive system and its hormonal regulation; 2. Structure of male reproductive system and its hormonal regulation. 3. Structure of the immune system, types of lymphocytes. Lymphokines. 4. Hormones produced by the hypophysis, regulation by the hypothalamus. Endocrine glands. 5. Gastrointestinal system, part 1. Structure of the oral cavity. 6. Gastrointestinal system, part 2. Stomach and intestines, structure and function. 7. Gastrointestinal system, part 3. Relationship between structure and function of the liver. 8. Respiratory system. Exchange of O2 – CO2 in pulmonary alveoli. 9. Urinary system. Relationship between nephrons and blood vessels. 10. Structure and function of skin, development of the mammary gland. 11. Nervous system. Structure of eye, function of the retina. 12. Sensory organs: ear 13. Concluding remarks.

Seminars & practical classes: Part I (General Histology) 1. Various cell types, histological technique. 1. Compartments of cells and their function. 2. Cell cycle and its regulation. Cell division. 3. Structure and function of epithelial tissue, glands. 4. Structure and function of connective tissue proper and adipose tissue. 5. Structure of cartilage and bone. 6. Development of various types of bones, rebuilding of bones. 7. Structure, organization and function of peripheral nervous system. 8. Structure, organization and function of muscular tissue. 9. Blood and bone marrow. Formation of particular types of blood cells. 10. Structure of heart and vessels with particular emphasis on function of endothelial cells. Circulatory system. 11. Demonstration of histological slides before first intermediate examination. 12. First intermediate examination - slides. 13. First intermediate examination - MCQ test. 14. First intermediate examination - retake. Part II (Microscopic Anatomy) 1. Female reproductive system. 1. Male reproductive system. 2. Lymphatic (immune) system. 3. Endocrine glands. 4. Gastrointestinal system - part 1. 5. Gastrointestinal system - part 2. 6. Gastrointestinal system - part 3. 7. Respiratory system. 8. Urinary system. 9. Skin and its appendages, mammary gland. 10. Nervous system and sensory organs: eye. 11. Demonstration of histological slides before second intermediate examination. 12. Second intermediate examination slides. 13. Second intermediate examination, MCQ test. 14. Second intermediate examination - retake. Demonstration of histological slides before final examination. Discusion on topics of part I & II. Textbooks 1. Gartner L. P., Hiatt J. L., “ Color Textbook of Histology”, Saunders Elsevier, third edition 2. T.W. Sadler Medical embryology, Williams & Wilkins, Baltimore, last edition. Additional 1. L. C. Junqueira, J. Carueiro, R. O. Kelley Basic Histology, Appleton & Langue, Stamford, last edit. 2. Kierszenbaum A: Histology and Cell Biology: An Introduction to Pathology, Elsevier, second edition 3. B. Alberts, D. Bray, K. Hopkin, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter Essential Cell Biology, Garland Publishing, New York, third edition. 4. Sobotta/Hammersen Histology – Color Atlas of Microscopic Anatomy, Urban & Schwarzenberg, Baltimore-Munich, last edition 5. Gartner L. P., Hiatt J. L. Color Atlas of Histology Lippincott Williams & Wilkins, Baltimore, Philadelphia, last edition CELL PHYSIOLOGY Chair & Department of Histology and Embryology, Centre for Biostructure Research Address: 5 Chałubińskiego Street (Anatomicum) 02-004 Warsaw e-mail address: histologia.wum.edu.pl Phone/fax 022 629 52 82; Head: Prof. Jacek Malejczyk, Ph.D.

Curricular affairs: Prof. Jacek Malejczyk, MD, PhD - phone 022 629 52 82, 022 622 00 29

Number of teaching hours:  seminars: 10 hrs  practical classes: 24 hours

Assessment of student performance: On completion of the course students are expected to take written final examination (MCQ).

Aim of the course: In the course of lectures, seminars and classes of Histology students had obtained basic information concerning structure and function of cells, tissues and organs. During seminars and classes of cytophysiology we shall present complex processes involved in regulation of function of particular cells and their populations. We shall particularly stress those processes occurring in cells and tissues, which have direct relation to clinical problems and which are involved in pathogenesis of most important diseases occurring in contemporary societies. Students will get acquainted with mechanisms governing cell cycle and controlling cell proliferation as well as with results of their disturbances, frequently leading to neoplasm formation. We shall also present molecular mechanisms of apoptosis and importance of its monitoring in therapy. Students will be taught how signals from the environment reach the cells and how cells respond to them. Moreover, we shall present contemporary views concerning cell ageing, its relation to senescence of the whole organism and hypotheses explaining why neoplastic cells are immortal. To facilitate understanding of methods used in recent years in research and in diagnostics we will demonstrate basic histochemical and immunocytochemical procedures. Finally, owing to the participation of the Department of Transplantology and Central Tissue Bank students will be able to learn about techniques used for tissue preservation for transplantation and fate of such transplants in an organism. Recent years witness fast development of molecular medicine and thus, the purpose of cytophysiology teaching is to ensure that students are informed about its most important trends. To fulfil this goal compendium containing latest data is provided. The educational aim of the Department will be achieved when students comprehend discussed processes and understand their importance for the wellbeing of the patient. They should be able to link acquired knowledge to pathogenesis of diseases and understand the principles of molecular tests used for their diagnostics. General regulations of the department 1. Students should read respective chapters in the textbook(s) before practical classes. Students have to participate in discussion during practical classes and follow instructions of their professors. These include inspection of histological slides or other materials provided as illustrations to given topic. Class is dismissed when professor checked and approved the notes of students. 2. No more than 2 absences are allowed during the course, irrespective of the cause (justified or unjustified absence). Students who miss more than 2 classes will not get a credit and will not qualify for the final examination. 3. Students should be aware that coming more than 15 minutes late to the class is considered an absence 4. Final examination consists of 50 questions in MCQ format. Each question is scored 1 point. The minimal score required to pass the exam is 30. 5. Final examination will be scheduled in June, the retake in September. The dates of these examinations are appointed by the Dean’s Office and are not subjects of change. Department’s policy regarding cheating on examinations Cheating on examinations is unethical and violates University law. Individuals who actively or passively participate in this activity will be removed from the examination and fail the exam. Active cheating includes copying answers given by other students or using illegal notes or electronic devices that can be used for of communication or data storage. In general no electronic devices are allowed during examination in our Department. Examples of passive cheating include giving answers to other students during test or facilitating the act of cheating by other means (such as unjustified displaying of the answers to others). Therefore Students should take all precautions to prevent an occurrence of such situation. Chair of the Department obliges examiners and examinees to exercise this policy rigorously.

Seminars and practical classes: 1. DNA and chromosomes. DNA replication, repair and recombination. 2. From DNA to protein. Control of gene expression. 3. Membrane structure. Membrane transport. 4. Intracellular compartments and transport. 5. Cytoskeleton and cell movement. 6. Cell communication. 7. Cell cycle control and cell death. Cell division. 8. Cell aging. 9. Tissues and cancer. 10. How cells are studied. 11. Cell therapy. 12. Tissue banking. 13. Concluding remarks. 14. Final Examination. 15. Final Examination - retake.

Textbooks 1. B. Alberts, D. Bray, K. Hopkin, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter Essential Cell Biology, Garland Publishing, New York, third edition. 2. Kierszenbaum A: Histology and Cell Biology: An Introduction to Pathology, Elsevier, second edition HUMAN EMBRYOLOGY Chair & Department of Histology and Embryology, Centre for Biostructure Research Address: 5 Chałubińskiego Street (Anatomicum) 02-004 Warsaw e-mail address: histologia.wum.edu.pl Phone/fax 022 629 52 82; Head: Prof. Jacek Malejczyk, Ph.D.

Curricular affairs: Prof. Jacek Malejczyk, MD, PhD - phone 022 629 52 82, 022 622 00 29

Number of teaching hours: seminars: 3 hours practical classes: 6 hours

Assessment of student performance: On completion of the course students are expected to take final examination. Written final examination (MCQ test) will include early stages of embryonic and fetal development.

The aim of the course: During embryology course students will be acquainted with early stages of human embryo and fetus development.

General regulations of the department  Students should read respective chapters in the textbook(s) before practical classes. Students have to participate in discussion during practical classes and follow instructions of their professors. These include inspection of histological slides or other materials provided as illustrations to given topic. Class is dismissed when professor checked and approved the notes of students.  No more than 1 absence is allowed during the course, irrespective of the cause (justified or unjustified absence). Students who miss more than 1 class will not get a credit and will not qualify for the final examination.  Students should be aware that coming more than 15 minutes late to the class is considered an absence  Final examination consists of 30 questions in MCQ format. Each question is scored 1 point. The minimal score required to pass the exam is 18.  Final examination will be scheduled in February, the retake in March. The dates of these examinations are appointed by the Dean’s Office and are not subjects of change.

Department’s policy regarding cheating on examinations Cheating on examinations is unethical and violates University law. Individuals who actively or passively participate in this activity will be removed from the examination and fail the exam. Active cheating includes copying answers given by other students or using illegal notes or electronic devices that can be used for of communication or data storage. In general no electronic devices are allowed during examination in our Department. Examples of passive cheating include giving answers to other students during test or facilitating the act of cheating by other means (such as unjustified displaying of the answers to others). Therefore Students should take all precautions to prevent an occurrence of such situation. Chair of the Department obliges examiners and examinees to exercise this policy rigorously. Topics of seminars: 1. Capacitation, acrosomal reaction, fertilization. In vitro fertilization (IVF). 2. The embryonic period. The fetal period. 3. Fetal membranes and placenta.

Topics of practical classes: 1. Fertilization and cleavage of mouse ova: slides:  oocyte at II metaphase stage: meiotic division spindle, I polar body and zona pellucida are expected to be identified (no.1),  fertilized eggs: sperm head, II polar body and zona pellucida are expected to be identified. Note difference in structure of egg and sperm chromatin (no. 2),  zygote at the pronuclear stage: female and male pronuclei, II polar body and zona pellucida are expected to be identified (no. 3),  4- and 8-blastomere embryos (no. 4),  8-blastomere embryos before and after compaction (no. 5),  blastocyst. Note inner cell mass, trophectoderm, zona pellucida (no.6),  haploid oocyte after parthenogenetic activation with II polar body (no.7). 2. Determination of menstrual cycle phases: slides:  vagina (no. 96), fragments of endometrium obtained from biopsy: no. 105 - proliferative phase, no. 105a - secretory phase,  smears of vaginal epithelium (no. 235): a - early estrogenic phase, b - late estrogenic phase, c - luteal phase, d – pregnancy.  Normal desquamated cells from the surface of vaginal part of the uterus (period of full sexual maturity). Vaginal epithelium superficial layer cells with pyknotic or vesicular nucleus, intermediate layer cells, single and grouped leukocytes (no. 230).  Menopause, desquamated epithelial cells (no. 231). 3. Human fetal membranes and placenta. Demonstration of the in vitro fertilization laboratory; I Chair and Department of Obstetrics and Gynecology: slides:  placenta (no. 107),  umbilical cord (no. 6).

Basic textbook: 1. Langman’s Medical Embryology, T. W. Sadler, last edition MEDICAL BIOLOGY Department of General Biology and Parasitology Address: 5 Chałubińskiego Street., 02-004 Warsaw Phone: 022 621 26 07; fax: 022 628 53 50, e-mail: [email protected] Head: Prof. Barbara Grytner-Zięcina, MD, Ph.D.

Curricular affairs: Monika Dybicz, MD, Ph.D.

Number of teaching hours: lectures - 10 hours seminars - 30 hours

Assessment of student performance: On completion of the course students are expected to take the test of 30 multiple choice questions.

The aim of course: The aim is to acquaint the students with the principles of heredity, background of genetic diseases and molecular methods used in diagnosis of human disorders.

Topics of lectures: 1. Organization of the human genome. Model organisms. 2. Principles and methods of DNA cloning. Reproductive and therapeutic cloning. 3. Plant transformation, its role in agriculture and safety of GMO. 4. Transgenic animals and their benefits to human health. 5. Gene therapy: therapeutic mechanisms and strategies.

Topics of seminars: 1. Classical genetics; Mendel’s laws and variations in Mendelian inheritance. 2. Unifactorial inheritance of autosomal traits (dominant and recessive normal traits and diseases). 3. Chromosome sex determination (normal sex determination and its disorders). Sex-linked inheritance of dominant and recessive traits. 4. Multifactorial inheritance (continuous and discontinuous traits). Inheritance of blood group systems. Hemoglobinopathies. Genetics of tissue compatibility systems. 5. Mechanisms of gene mutations. Somatic vs. germline mutations. Spontaneous and environmental damage to DNA. Disorders of metabolism. 6. Chromosomal aberrations (numerical and structural abnormalities. Syndromes induced by chromosomal aberrations. 7. Cytogenetics. Banding techniques, normal and abnormal karyotype study. Molecular techniques (FISH, chromosome painting etc.). 8. Molecular biology techniques as a tool for gene mutations identification. Southern blotting, PCR, RFLP, sequencing. Forensic medicine and DNA fingerprinting. 9. Population genetics. Hardy-Weinberg equation. Principles of pedigree analysis. 10. Final assessment test.

Basic textbook: Thompson & Thompson Genetics in Medicine Revised Reprint, 6th Edition. R. L. Nussbaum, R. R. McInnes, H. F. Willard. W. B. Saunders Company, 2004; or Medical Genetics 3rd Edition. L.B. Jorde, J.C. Carey, M.J. Bamshad, R.L. White. Mosby, 2003. ETHICS IN MEDICINE Department of Bioethics Address: 81 Zwirki and Wigury Street, 02-091 Warsaw phone/fax: 022 827 0307 Head: Alicja Domańska, MD, Ph.D. Curricular Affairs: Paweł Łuków, MD, PhD.

Number of teaching hours: 14 hours of lecture 16 hours of seminar

Assessment of student performance: Activity in class. Final test.

Aim of the course: To acquaint students with the theoretical foundations of ethics and moral problems encountered in medicine. Attention is paid to development of student ability to approach moral dilemmas of medical practice. Lectures are accompanied by seminars in which students discuss real-life cases. The leading theme of seminars is patient informed consent to medical treatment.

Topics of lectures: 1. Basic concepts of theoretical ethics; types of ethics; the need for professional ethics. 2. Moral reasoning. Types of ethical theories. 3. The ethical theories of J. S. Mill, Aristotle, and I. Kant. 4. The right to health care. Models and systems of health care provision.

Topics of seminars: 1. Informed consent. The physician-patient relationship. 2. Truth telling, its moral significance and limitations. 3. Confidentiality. 4. The ethics of clinical trials. 5. Classical arguments in medical ethics.

Basic textbook: T. L. Beauchamp, J. F. Childress, Principles of Biomedical Ethics, Oxford University Press 1994 (fourth edition), chapters 3-7. BEHAVIORAL SCIENCES II Department of Psychiatry Address: 8 Kondratowicza Street, 03-242 Warsaw Phone/fax: 022 326 58 92 Head: Prof. Andrzej Kokoszka, MD, PhD

Curricular affairs: Prof. Andrzej Kokoszka, MD, PhD

Course location Lectures/seminars - the main building of the Medical University of Warsaw, 61 Żwirki i Wigury Street Classes - Bródno Hospital – 8 Kondratowicza Street and Psychotherapy Center at 112 .Sobieskiego Street. The detailed time-table will be presented during the first lecture at the beginning of each semester.

The course will be conducted on each Thursday 8.00 – 11.15 (4 academic hours with one 15 minutes break)

Number of teaching hours: Lectures 32 Seminars: 32 Classes: 36

Assessment of student performance: Active participation in seminars is needed, including essays and case preparation, and is a basis for credit. There is the final written exam at the end of the course.

The aim of the course: As a component of two years course in behavioral sciences and mental disorders (psychiatry) offered the students are introduced to the essentials of medical psychology. The main areas covered include individual behavior, mental functioning, personality development and assessment, basic psychological and psychopathological theories, family approach and physician patient relation including techniques of interviewing.

Topics of lectures and seminars 1. Introduction – biopsychosocial approach 2. Psychosomatic medicine 3. Psychoanalytic theory 4. Learning theory 5. Individual development 6. Aging, death and bereavement 7. Genetics, psychophysiology of behavior 8. Biological Assessment

Classess 1. Physician patient interview 2. Clinical interview 3. Clinical assessment 4. Ethical and legal issues 5. Lectures and seminars 6. Psychopathology 7. Family, culture 8. Sleep and sleep disorders 9. Sexuality 10. Child psychiatry 11. Aggression and abuse 12. Epidemiology 13. Statistical analyses 14. Schizophrenia and other psychotic disorders 15. Mood disorders 16. Anxiety and other neurotic disorders 17. Personality disorders 18. Substance abuse 19. Psychotherapy

Basic textbook:

Fadem B.:Behavioral Science. 4th Ed., Lippincott Williams7 Wilkins, Philadelphia, 2004 Additional Textbook: Wiener M J. Breslin N.A. Behavioral science. 3rd Edition. Williams & Wilkins, Baltimore, 1995. IMMUNOLOGY Department of Immunopathology of Infectious and Parasitic Diseases Address: 3C Pawińskiego Str, 02-106 Warsaw Phone: 22 57 20 709; Fax: 22 88 313 60; e-mail: [email protected] Head: Prof Marek Radkowski, MD, PhD

Curricular affair: Prof Marek Radkowski MD, PhD, Marta Polanska. MD, Ph.D Lectures and seminars will be held at the Didactic Centre, 2a, Trojdena St., 02-109 Warsaw.

Number of teaching hours: lectures 10hrs, seminars 20 hrs

Assessment of student performance: colloquium, test exam

The aim of course: Human immunology – basic knowledge

Topics of lectures: 1. Function of the immune system. 2. Development, maturation and function of T-cells. 3. Development, maturation and function of B-cells. 4. Mucosa associated lymphoid system. 5. Immunity to infections. 6. Advances in transplantation immunology. 7. Hypersensitivity reactions. 8. Mechanisms of type I hypersensitivity. 9. Tumor immunology. 10. AIDS.

Topics of classes: 1. Structure and functions of lymphoid organs. Structure of antibodies and T cell receptors. 2. The source of immunoglobulin and TCR diversity. Monoclonal antibodies. 3. Part I: Lymphocyte subpopulations. Antigen presentation. The role of cytokines and surface molecules in proliferation and differentiation of lymphocytes. Part II: major histocompatibility complex. Types of the immune response. Regulation of humoral and cell-mediated immunity. 4. Innate immunity. The role of complement in the immune response. Antibody dependent cell-mediated cytotoxicity. Mechanisms of lymphocyte cytotoxicity. 5. Colloquium. 6. Part I: Transplantation immunology. The mechanisms of allograft rejection. Transplantation tolerance. Part II: Stimulation of the immune system. 7. Immune system as a place of microbes invasion. The ways of avoiding the immunity. 8. Part I: Immune tolerance and autotolerance. Part II: Autoimmune diseases. 9. Tumor immunology. Immunological enhancement. Tumor evasion strategies. 10. Primary and secondary immunodeficiences. AIDS.

Basic textbooks: Immunology 6e, Kindt, Goldsby, Osborne POLISH LANGUAGE Foreign Language Center Address: The Didactic Center, 2a, Trojdena Street, 02-109 Warsaw phone: 022 572 08 63, fax: 022 572 08 64 ; e-mail: [email protected]

Head: Joanna Ciecierska MA

Curricular affairs: Maria Janowska MA, Świetlana Sikorska MA, Małgorzata Kierepka MA

Number of teaching hours: The course covers 80 hours of classes:45 hours in autumn semester and 35 hours in spring semester.

Assessment of student performance: To obtain a credit after each term a student has to attend classes regularly and pass all the assigned written tests successfully (minimum score is 55% correct answers). Please be informed, that according to the academic rules students are obliged to take part in all the classes. Classes start punctually according to the timetable. Students coming late (more than 10 minutes after the time) will not be allowed into the classroom and this will be treated as unexplained absence. No absence will be accepted except the one for which a student has a valid medical note. The note must be submitted to the teacher within three days from the visit to the doctor. A student’s absence on the assigned day of the test will result in not obtaining a credit. Students who fail the test can be given a chance to sit a retake test twice, provided they took part in classes regularly. The days of the retake tests are set by the teacher in agreement with the Dean’s Office. The first retake can be not earlier than a week from the day of the test. The second retake can be not earlier than two weeks from the day of the first retake and not later than the last day before the retake examination session. The result of the second retake is the final mark the student receives. There are no more possibilities of any other retakes. The student who fails the second retake must repeat the part of the program he/she has failed.

Those students who are independent users*of the Polish language may be exempted from attending the compulsory course in General Polish with a Polish for Medical Purposes component(80 h in Year I and 80 h in Year II, a total of 160 h) if they pass an examination at the beginning of Year I. The examination at Level B2 as described in the Common European Framework will test four skills: reading, writing, listening and speaking. At the introductory meeting in the first week of the academic year, the students will be given detailed information about the examination requirements, including sample tasks, grading system and suggested course books. The examination itself will be held within four weeks of the introductory meeting. Those who pass the examination will be exempted from attending the Polish course and this exemption together with the examination result will be documented in their student’s record book. Those who do not take the examination at the date given or fail the examination will have to attend the 160-h course as stipulated in the curriculum. Students may not resit this particular examination since its purpose is confirm the declared proficiency in the Polish language. All students, irrespective of their declared baseline proficiency in the Polish language are required to take in Year 3 a 60-h course of Polish for Medicine” Communication Skills in Medicine ” followed by the final written and oral examination. *Independent users can understand the main ideas of complex text on both concrete and abstract topics, including technical discussions in his/her field of specialization. Can interact with a degree of fluency that makes regular interaction with native speakers quite possible without strain for either party. Can produce a clear, detailed text on a wide range of subjects and explain a viewpoint on a topical issue giving the advantages and disadvantages of various options. From ‘The Common European Framework’.

The aim of the course: The aim of the Ist year Polish Language course is to introduce basic language structures, which will enable the students to communicate in everyday situations.

Topics of classes: 1. Polish phonetics and spelling rules. Polish alphabet. 2. Formal introductions and greetings. The verb: to be. Polish verb system-conjugations. 3. Informal introductions and greetings 4. Getting registered at the student’s hostel-basic conversations. Numbers in Polish. 5 Describing people. Adjectives. Grammatical gender of Polish nouns. Verbs-Present Tense 6. Countries and nationalities. Instrumental case. 7. Describing members of the family. Instrumental case to express professions. Direct object- Accusative case. 8. Likes and dislikes. Situations and sentence patterns. Accusative case vs. Genitive case.. 9. First telephone conversations. Cardinal vs. ordinal numbers. Telling the time. Verbs- Future Tense. 10.Locating places. Locative expressions. 11.Asking the way. 12. Locating means of transportation. 13. Shopping. Accusative case: nouns + adjectives . Partitive Genitive. 14. Eating out: at a restaurant, café, pub. Instrumental case after preposition ”z” Instrumental case: nouns + adjectives. 15. Describing places: a) a room in a student’s hostel b) a private apartment c) a hospital Locative expressions. Possessive Genitive. 16. Everyday activities. Days of the week. Names of the months. Present Tense. Verb Conjugations I,II,III,IV Verbs followed by Instrumental: opiekować się, zajmować się, interesować się. 17. Future Tense. 18. Past Tense. 19. Aspect of the past tense verbs.

Basic textbook: Maria Janowska, Świetlana Sikorska:”Ja też chcę mówić po polsku”

Complementary materials: Handouts prepared by the teachers. LATIN LANGUAGE Foreign Language Center Address: The Didactic Center, 2a, Trojdena Street, 02-109 Warsaw phone: 022 572 08 63, fax: 022 572 08 64 ; e-mail: [email protected]

Head: Joanna Ciecierska MA

Curricular affairs: Beata Olędzka MA; Jadwiga Niklewicz MA

Number of teaching hours: The course covers 60hours of classes: 30 hours in autumn semester and 30 hours in spring semester.

Assessment of student performance: To obtain a credit after each term a student has to attend classes regularly and pass all the assigned written tests successfully (minimum score is 55% correct answers). Please be informed, that according to the academic rules students are obliged to take part in all the classes. Classes start punctually according to the timetable. Students coming late (more than 10 minutes after the time) will not be allowed into the classroom and this will be treated as unexplained absence. No absence will be accepted except the one for which a student has a valid medical note. The note must be submitted to the teacher within three days from the visit to the doctor. A student’s absence on the assigned day of the test will result in not obtaining a credit. Students who fail the test can be given a chance to sit a retake test twice, provided they took part in classes regularly. The days of the retake tests are set by the teacher in agreement with the Dean’s Office. The first retake can be not earlier than a week from the day of the test. The second retake can be not earlier than two weeks from the day of the first retake and not later than the last day before the retake examination session. The result of the second retake is the final mark the student receives. There are no more possibilities of any other retakes. The student who fails the second retake must repeat the part of the program he/she has failed. The course ends with the written examination two weeks before the end of the classes or in the last week of the spring semester. Students who do not pass the examination with a positive grade are given a chance to retake the examination in the first week of the examination session.

The aim of the course: The course of Latin for medical purposes includes, in addition to medical terminology, basic grammar knowledge such as nouns, adjectives, adverbs and prepositions necessary to write medical diagnoses.

Topics of practical classes: 1. A brief history of Latin and an introduction to the language 2. Verbs 3. Nouns and adjectives of the 1st, 2nd and 3rd decl. 4. Nouns of the 4th and 5th decl. 5. Prepositions 6. Adverbs 7. Comparison of adjectives 8. Selected pronouns 9. Numerals 10. Latin prescription

Basic textbooks: Beata Olędzka: Latin in Medicine. Course for medical students, Oficyna Wydawnicza WUM 2008.

Complementary textbooks: 1. Latin Course for Students of Medicine by J.Niklewicz, Oficyna Wydawnicza WUM. 2. Ryszard Aleksandrowicz, Jerzy Gielecki, Witold Gacek: Dictionaty of Anatomical Terms Latin - Polish - English, Wydawnictwo Medyczne PZWL Warsaw 1997. 3. Handouts prepared by tutors. PHYSICAL EDUCATION AND SPORTS Department of Physical Education and Sports Address: 2 Trojdena Street, 02-109 Warsaw Phone: 022 57 20 528; fax: 022 57 20 541. e-mail: [email protected] Classes will be held at 27,Ciołka St.

Head: Jerzy Chrzanowski, M.Sc.

Curricular affairs: Jerzy Chrzanowski M.Sc

Number of teaching hours: The course covers 60 hours of practical training

Assessment of students performance: For completion of the course students are expected to regularly attend classes and improve their results or skills.

GOALS AND OBJECTIVES: It is the aim of the Physical Education & Sports program to enhance the physical, motor, mental and social development of all students. It is the purpose of the Physical Education & Sports Department to offer programs which are designed to meet the varying skill and ability levels of the student population. Specific objectives of the Physical Education & Sports program are: 1. To develop basic motor skills through a wide variety of activities. 2. To promote physical fitness through activities which condition the organic systems of the body. 3. To understand the rules, techniques and strategies involved in physical activities and sports. 4. To encourage social efficiency and good human relations through physical activities. 5. To acquire an appreciation of and respect for good health and well being which is promoted through participation in lifetime physical activities. Program of education: The program offers a Basic Physical Education and a wide variety of courses by academic clubs which include skills in individual sports, team sports, fitness activities and recreational activities. Students are encouraged to participate in courses which are new, different and challenging!

Evaluation of the Physical Education and Sport training participation: Physical fitness testing (Cooper’s test; Modified Harvard’s test; etc.) Evaluation of technical skills (for team sports games) The course promotion is granted to the students who attended 15 trainings during each semestr.

The basic skills courses may include Therapeutic Exercise on individual requirements. Basic Skills Courses cover Regular Physical Education.

The higher skills courses correspond to the intercollegiate sports offered (Academic Sports Association clubs). Medical University of Warsaw clubs of the Academic Sports Association of Poland (AZS): Aerobics and Pilates Soccer Basketball Swimming Volleyball Horse Riding Self Defense (Judo, Karate, Capoeira) Weight Training Snow Skiing/Snowboarding Bicycling Climbing Table tenis Additionally, students may attend Water Life Saving training as a utilitary sport

REGISTRATION FOR PE & S Physical Education & Sport registration is a part of the Web Registration process.

MEDICAL POLICIES All students are expected to meet all of the PE&S requirements. Any student who has a medical circumstance which they feel precludes them from completing any or all of the requirement must see the University physician. The University physician will then work with the department to determine a course of action, with options including Therapeutic Exercise program, an appropriate selection of courses or an exemption from the General Education requirement. A student who is already enrolled in a course and who suffers a short term illness or injury should work with the instructor to make-up the missed class time.

The Department of Physical Education and Sports welcomes students to its web page. www.studiumwfis-am.waw.pl This page is designed to answer the most commonly asked questions regarding the Physical Education & Sports (PE&S) requirement at Medical University of Warsaw.

LIBRARY TRAINING The Main Library Address: ul. W.Oczki 1, 02-007 Warszawa Phone/fax: 022 628 22 37 Head: Irmina Utrata, MSc

2 hours of instruction

The library training for the students of the first year. The aim of this training is to make students familiar with the work of the library and the rules of using its collections by means of various catalogues. This training covers also the ways of accessing and using the Internet in the Multimedia Reading Room.

SUMMER MEDICAL TRAINING PROGRAM

First year students undergo a one-month (total 160 hours) nursing training being attached to the nursing personnel as nursing assistants (auxiliaries at teaching hospitals of medical academies) universities either in Poland or selected foreign countries. At a teaching hospital in Poland the head of the ward/department or an appointed instructor in charge provides a detailed program as well as scheduled duties and maintains both supervision and assessment of student’s performance. The instructor in charge of first year students should be a fully qualified nurse who will supervise all nursing duties performed by students also those carried out with regard to patients in severe condition requiring intensive care.

The main goals of the training are: 1. acquire skills in performing ward routines e.g., taking temps and BP, making beds and changing bedclothes, maintaining patients’ personal hygiene, offering bedpans and urinals, feeding patients, preparing drugs ordered for administration 2. learn the techniques of giving subcutaneous and intramuscular injections and assisting during instituting intravenous infusions. 3. to acquaint students with procedures concerning patients’ registration, types of records and filing system used in the outpatients’ departments, 4. to provide information on rules of referring patients on sick leaves, releasing sickness certificates, referrals to specialists, filling in particular forms and letters, 5. to teach the techniques of preparing surgical dressing materials and surgical instruments for sterilization, 6. to acquaint students with the functioning of the treatment room, to teach them to give subcutaneous, intracutaneous and intramuscular injections, to perform diagnostic tests and to interpret the results, 7. to teach the technique of immobilization, 8. to teach the theory and, if possible, the practical application of the first aid in emergencies, 9. to prepare students to assist the physician in minor procedures, 10. to prepare students to assist the physician in examining outpatients and participating in home rounds.

Throughout the course of the training students are expected to make records of their activities and procedures performed. They are also assessed by the instructor in charge and are finally granted their passing mark by the head of the department. Certificates written in English or translated should be submitted to the Dean’s Office of the Medical University of Warsaw by October 5th of the subsequent academic year.