JOURNAL of VIROLOGY VOLUME 61 * DECEMBER 1987 * NUMBER 12 Arnold J
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JOURNAL OF VIROLOGY VOLUME 61 * DECEMBER 1987 * NUMBER 12 Arnold J. Levine, Editor in Chief Thomas E. Shenk, Editor (1989) (1989) Princeton University Princeton University Princeton, N.J. Princeton, N.J. Anna Marie Skalka, Editor (1989) Bernard N. Fields, Editor (1988) Fox Chase Cancer Center Harvard Medical School Philadelphia, Pa. Boston, Mass. George F. Vande Woude, Editor (1992) Robert A. Lamb, Editor (1992) NCI-Frederick Cancer Research Facility Northwestern University Frederick, Md. Evanston, Ill. Robert A. Weisberg, Editor (1988) Michael B. A. Oldstone, Editor (1988) National Institute of Child Health Scripps Clinic & Research Foundation and Human Development La Jolla, Calif. Bethesda, Md. EDITORIAL BOARD James Alwine (1988) Walter Gerhard (1989) Warren Masker (1987) Joseph Sambrook (1988) David Baltimore (1987) Joseph C. Glorioso (1989) Thomas Merigan (1989) Charles E. Samuel (1989) Tamar Ben-Porat (1987) Stephen P. Goff (1988) George Miller (1987) Priscilla A. Schaffer (1987) Kenneth I. Berns (1988) Larry M. Gold (1988) Lois K. Miller (1988) Sondra Schlesinger (1989) Michael Botchan (1989) Hidesaburo Hanafusa (1989) Peter Model (1989) Manfred Schubert (1988) Thomas J. Braciale (1988) John Hassell (1989) Bernard Moss (1989) Bart Sefton (1988) Joan Brugge (1988) William i. Hayward (1987) Opendra Narayan (1988) Bert L. Semler (1989) Michael J. Buchmeier (1989) Roger Hendrix (1987) Joseph R. Nevins (1988) Charles J. Sherr (1987) Barrie J. Carter (1987) John J. Holland (1987) Erling Norrby (1989) Saul J. Silverstein (1988) John M. Coffin (1989) Nancy Hopkins (1989) Nancy G. Nossal (1987) Patricia G. Spear (1987) Charles N. Cole (1989) Peter M. Howley (1987) Dennis O'Callaghan (1989) Bruce Stillman (1988) Geoffrey M. Cooper (1987) Alice S. Huang (1987) J. Thomas Parsons (1989) Mark F. Stinski (1989) Neal Copeland (1989) Steve Hughes (1988) Ulf G. Pettersson (1989) James Strauss (1987) Donald Court (1987) Tony Hunter (1989) Lennart Philipson (1987) F. William Studier (1987) Richard Courtney (1989) Richard Hyman (1989) Lewis I. Pizer (1987) Lawrence S. Sturman (1988) Clyde S. Crumpacker II Nancy Jenkins (1989) Carol Prives (1989) John M. Taylor (1987) (1988) Jack D. Keene (1988) R. Frank Ramig (1988) Howard M. Temin (1988) Thomas Curran (1988) Thomas J. Kelly, Jr. (1988) Fred Rapp (1987) Inder Verma (1989) Walter Doerfler (1989) Elliott Kieff (1987) Dan S. Ray (1989) Edward K. Wagner (1989) Elvera Ehrenfeld (1989) David Knipe (1988) Solon L. Rhode (1989) Raymond M. Welsh, Jr. (1988) Robert N. Eisenman (1988) Daniel Kolakofsky (1989) Gordon M. Ringold (1987) Gail Wertz (1988) Suzanne U. Emerson (1989) Michael Lai (1988) Harriet Robinson (1988) Reed B. Wickner (1988) Mary K. Estes (1989) Robert A. Lazzarini (1987) William S. Robinson (1989) Eckard Wimmer (1988) Ellen Fanning (1988) Myron Levine (1988) Bernard Roizman (1988) Owen Witte (1989) Emanuel Faust (1987) Maxine Linial (1988) John K. Rose (1988) Charles Hamish Young (1989) S. Jane Flint (1987) Douglas R. Lowy (1989) Naomi Rosenberg (1989) Harald zur Hausen (1989) Donald Ganem (1988) Malcolm Martin (1989) Roland R. Rueckert (1988) Costa Georgopolous (1989) Robert Martin (1987) Norman P. Salzman (1987) Helen R. Whiteley, Chairman, Publications Board Kirk Jensen, Director of Publications Linda M. Illig, Managing Editor, Journals Judith Nedrow, Production Editor The Journal of Virology (ISSN 0022-538X), a publication of the American Society for Microbiology, 1913 I St., NW, Washington, DC 20006, is devoted to the dissemination offundamental knowledge concerning viruses of bacteria, plants, and animals. Investigators are invited to submit reports of original research in all areas of basic virology, including biochemistry, biophysics, genetics, immunology, morphology, physiology, and pathogenesis and immunity. Instructions to authors are published in the January issue each year; reprints are available from the editors and the Publications Department. The Journal is issued monthly, one volume per year. The nonmember subscription price is $350 per year; single copies are $25. The member subscription price is $41 (foreign, $56 [air drop shipping]) per year; single copies are $8.00. Correspondence relating to subscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submitted manuscripts, and general editorial matters should be directed to the ASM Publications Department, 1913 I St., NW, Washington, DC 20006 (phone: 202 833-9680). Claims for missing issues from residents of the United States, Canada, and Mexico must be submitted within 3 months after publication of the issues; residents of all other countries must submit claims within 6 months of publication of the issues. Claims for issues missing because offailure to report an address change or for issues "missing from files" will not be allowed. Second-class postage paid at Washington, DC 20006, and at additional mailing offices. POSTMASTER: Send address changes to Journal of Virology, ASM, 1913 I St., NW, Washington, DC 20006. Made in the U.S.A. Copyright C) 1987, American Society for Microbiology. ftI 4fl'itA- L ±flhIU. (41t. All Rights Reserved. The code at the top of the first page of an article in this journal indicates the copyright owner's consent that copies of the arti- cle may be made for personal use or for personal use of specific clients. 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Author Index Ahmed, Rafi, 3920, 3930 Esteban, Mariano, 3910 Lairmore, Michael D., 4038 Roivainen, Merja, 3749 Akita, Geoffrey Y., 4038 Estes, Mary K., 3950 Lasky, Laurence A., 3804 Rosen, Anders, 3870 Aldrich, Carol E., 3832 Evans, Leonard H., 3783 Lawrence, William C., 4023 Rowe, Martin, 3870 Alter, Harvey J., 3804 Evinger-Hodges, Mary Jean, Lazaro, Josd M., 3983 Rubenstein, Richard, 3688 Anderson, Carl W., 3879 3774 Leonard, John, 3726 Russell, Helena 1., 4038 Anderson K., 3855 Leung, Kiu, 4033 Aoki, Naoto, 3848 Falgout, Barry, 3759 Levis, Robin, 3809 Sakai, Koji, 3774 Arquint, Monique, 3694 Fersko, Regina, 3688 Levy, Jay A., 3804 Salas, Margarita, 3983 Ashida, Kouichi, 4012 Feunteun, Jean, 3992 Lewis, James B., 3879 Salfeld, Jochen, 3701 Fichelson, Serge, 4043 Lewis, T. L., 3820 Sanwal, B. D., 3795 Baker, Susan C., 3968 Finke, Jurgen, 3870 Lien, Jau-Min, 3832 Schaller, Heinz, 3701 Ball, L. A., 3855 Flomenberg, Phyllis R., 3665 Lokensgard, J. R., 3820 Scheidtmann, Karl Heinz, Basilico, Claudio, 4055 Fraser, Nigel W., 3841 Lomniczi, Bela, 4030 3902 Beam, S. L., 3827 Freeman, J. Douglas, 4060 Love, Arthur, 3896 Scherneck, Siegfried, 3992 Bello, Leonard J., 4023 Fried, Mike, 3754 Schlicht, Hans J., 3701 Bellocq, Christine, 3960 Fujiwara, Kosaku T., 4012 Maa, Juehn-Shin, 3910 Seibl, Rudi, 3672 Benichou, Daniele, 3862 Fukushige, Shinichi, 3848 Mager, Dixie L., 4060 Sevoian, Martin, 3783 Ben-Porat, Tamar, 4030 Fultz, Patricia N., 4026 Marchioli, Carmine C., 3977 Shaw, James E., 4033 Berman, Phillip W., 3804 Mason, William S., 3832 Shen-Ong, Grace L. C., 3721 Bernad, Antonio, 3983 Gendelman, Howard E., 3726 Matsubara, Kenichi, 3848 Shieh, Chien-Kou, 3968 Beushausen, S., 3795 Ghiasi, Homayon, 3820 Mayfield, J. E., 3827 Shiga, Kiyoshi, 3848 Bhat, Bheem M., 3938 Girard, Marc, 3862 McClure, Harold M., 4026 Shinedling, Sidney, 3790 Blanco, Luis, 3983 Gisselbrecht, Sylvie, 4043 McClure, Jan, 3804 Smith, Marilyn S., 3769 Bordereaux, Didier, 4043 Gold, Larry, 3790 Merz, Patricia A., 3688 Soe, Lisa H., 3968 Bovi, Pasquale Delli, 4055 Gonda, Matthew A., 4046 Mettenleiter, Thomas C., 4030 Sola, Brigitte, 4043 Braun, Michael J., 4046 Goto, Naoaki, 3733 Miller, George, 3672 Spencer, John H., 3694 Bresser, Joel, 3774 Greene, Cornelia R., 4026 Miyajima, Nobuyuki, 4012 Spivack, Jordan G., 3841 Brian, E. Leigh, 3769 Gregory, Timothy, 3804 Moran, Patricia A., 3804 Srinivas, Ranga V., 4007 Butel, Janet S., 3950 Grussenmeyer, Thomas, 3902 Morein, Bror, 3896 Srinivasan, A., 4026 Butler, David, 4026 Gutierrez, Julio, 3983 Muller, Ulrich, 3710 Stevenson, Mario, 3741, 3774 Butler, Larry D., 3930 Murotsu, Tomoaki, 3848 Stott, E. J., 3855 Hermonat, Paul L., 3889 Strauss, James H., 3809 Carbone-Wiley, Arlene, 3902 Hermoso, Josd M., 3983 Nagaya, Tsutomu, 3848 Summers, Peter, 4019 Carp, Richard 1., 3688 Hirashima, Akikazu, 3946 Nagy, Eva, 3655 Swenson, R. Brent, 4026 Carpenter, Susan, 3783 Horswood, Robert, 4019 Nakamura, Takaaki, 3848 Chan, Wai-Kit, 3950 Horwitz, Marshall S., 3665 Narindrasorasak, S., 3795 Tambourin, Pierre E., 4043 Chang, Ming-Fu, 3968 Hovi, Tapani, 3749 Nesburn, Anthony B., 3820 Taylor, G., 3855 Chanh, Tran C., 3804 Howley, Peter M., 3889 Nishina, Hiroshi, 4012 Tegtmeyer, Peter, 3649 Chanock, Robert, 4019 Hu, Shiu-Lok, 3804 Nishizawa, Makoto, 3733, Timmins, James G., 3977 Chen, Mei, 3665 Huang, Henry V., 3809 4012 Tokino, Takashi, 3848 Chesebro, Bruce, 3783 Norbury, Christopher J., 3754 Tonna-DeMasi, Maria, 3688 Norrby, Erling, 3896 Chowdhury, Rukhsana, 3999 Iba, Hideo, 4012 Varsanyi, Tamas M., 3896 Clements, Janice E., 4046 Inokuchi, Yoshio, 3946 Vogel, Frank, 3992 Cobb, Kathy E., 3804 Ong, John, 3820 Volsky, David J., 3741, 3774 Compans, Richard W., 4007 Jamieson, Beth D., 3920, 3930 Ostrove, Jeffrey