JOURNAL OF VIROLOGY Volume 48 Contents for October 1983 No. 1

Animal Viruses Closed Circular Viral DNA and Asymmetrical Heterogeneous Forms in Livers from Animals Infected with Ground Squirrel Hepatitis Virus. BARBARA WEISER, DON GANEM, CHiRISTOPH SEEGER, AND HAROLD E. VARMUS* ...... 1-9 In Vitro and In Vivo Studies of Bovine Parvovirus Proteins. MURIEL LEDERMAN,* ROBERT C. BATES, AND ERNEST R. STOUT ...... 10-17 Independent, Spontaneous Mutants of Adenovirus Type 2-Simian Virus 40 Hybrid Ad2+ND3 That Grow Efficiently in Monkey Cells Possess Identical Mutations in the Adenovirus Type 2 DNA-Binding Protein Gene. CARL W. ANDERSON,* MEDORA M. HARDY, JOHN J. DUNN, AND DANIEL F. KLESSIG ...... 31-39 Structural Analysis of Integrated Polyomavirus DNA in a Polyoma- virus-Induced Hamster Tumor Cell Line. KAMAL CHOWDHURY, CLAUDE F. GARON, AND MARK A. ISRAEL* ... 40-51 Antigenic Drift in Influenza Virus H3 Hemagglutinin from 1968 to 1980: Multiple Evolutionary Pathways and Sequential Amino Acid Changes at Key Antigenic Sites. GERALD W. BOTH,* MERILYN J. SLEIGH, NANCY J. COX, AND ALAN P. KENDAL 52-60 Avian Oncovirus MH2: Molecular Cloning of Proviral DNA and Structural Analysis of Viral RNA and Protein. HANS W. JANSEN, TILO PATSCHINSKY, AND KLAUS BISTER* ...... 61-73 Chromatin-Like Structure of Adeno-Associated Virus DNA in In- fected Cells. CAROL J. MARCUS-SEKURA AND BARRIE J. CARTER* ...... 79-87 Comparative Inhibition of Cellular Transcription by Vesicular Sto- matitis Virus Serotypes New Jersey and Indiana: Role of Each Viral Leader RNA. BRIAN W. GRINNELL* AND ROBERT R. WAGNER ...... 88-101 Evidence for a New Form of Retroviral env Transcript in Leukemic and Normal Mouse Lymphoid Cells. MARTINE BOCCARA, MICHELE SOUYRI, CLAUDETTE MAGARIAN, EDWARD STAVNEZER, AND ERWIN FLEISSNER* ...... 102-109 Reversal of Fv-1 Host Range by In Vitro Restriction Endonuclease Fragment Exchange Between Molecular Clones of N-Tropic and B-Tropic Murine Leukemia Virus Genomes. LAWRENCE R. BOONE,* FRED E. MYER, D. M. YANG, CHIN-YIH OU, CHONG K. KOH, LAURENCE E. ROBERSON, RAYMOND W. TENNANT, AND WEN K. YANG ...... 110-119 Inhibition of Retrovirus DNA Supercoiling in Interferon-Treated Cells. MAHMOUD HULEIHEL AND MORDECHAI ABOUD* .... 120-126 Polyadenylic Acid Addition Sites in the Adenovirus Type 2 Major Late Transcription Unit. J. M. LE MOULLEC, G. AKUSJARVI, P. STALHANDSKE, U. PETTERSSON,* B. CHAMBRAUD, P. GILARDI, M. NASRI, AND M. PERRICAUDET ...... 127-134

Continued on following page Continuedfrom preceding page Organization of the Epstein-Barr Virus DNA Molecule. 111. Loca- tion of the P3HR-1 Deletion Junction and Characterization of the Notl Repeat Units That Form Part of the Template for an Abundant 12-O-Tetradecanoylphorbol-13-A'cetate-Induced mRNA Transcript. KUAN-TEH JEANG AND S. DIANE HAYWARD* ...... 135-148 Chemical Cleavage of Polyomavirus Major Structural Protein VP1: Identification of Cleavage Products and Evidence That the Receptor Moiety Resides in the Carboxy-Terminal Region. DAVID G. ANDERS AND RICHARD A. CONSIGLI* ...... 197-205 Comparison of Nonphosphorylated and Phosphorylated Species of Polyomavirus Major Capsid Protein VP1 and Identification of the Major Phosphorylation Region. DAVID G. ANDERS AND RICHARD A. CONSIGLI* ...... 206-217 Quantitation of a Simian Virus 40 Nonhomologous Recombination Pathway. DALE L. DORSETT, ILANA KESHET, AND ERNEST WINOCOUR* ...... 218-228 Structure of Simian Virus 40-+X174 Recombinant Genomes Isolat- ed from Single Cells. ERNEST WINOCOUR,* VERED LAVIE, AND ILANA KESHET ...... 229-238 Monoclonal Anti-Hemagglutinin Antibodies Detect Irreversible Antigenic Alterations That Coincide with the Acid Activation of Influenza Virus A/PR/834-Mediated Hemolysis. JONATHAN W. YEWDELL,* WALTER GERHARD, AND THOMAS BACHI .... 239-248 Persistent Infection of Some Standard Cell Lines by Lymphocytic Choriomeningitis Virus: Transmission of Infection by an Intra- cellular Agent. BERNARD A: M. VAN DER ZEIJST, BARBARA E. NOYES, MARC-EDOUARD MIRAULT, BARBARA PARKER, ALBERT D. M. E. OSTERHAUS, ELIZABETH A. SWYRYD, NANCY BLEUMINK, MARIAN C. HORZINEK, AND GEORGE R. STARK* ...... 249-261 Viral Proteins and RNAs in BHK Cells Persistently Infected by Lymphocytic Choriomeningitis Virus. BERNARD A. M. VAN DER ZEIJST, NANCY BLEUMINK, LIONEL V. CRAWFORD, ELIZABETH A. SWYRYD, AND GEORGE R. STARK* ...... 262-270 Synthesis of Hepatitis B Surface Antigen in Mammalian Cells: Expression of the Entire Gene and the Coding Region. ORGAD LAUB, LESLIE B. RALL, MARTHA TRUETT, YOSEF SHAUL, DAVID N. STANDRING, PABLO VALENZUELA, AND WILLIAM J. RUTTER* ...... 271-280 Analysis of Simian Virus 40 Chromosome-T-Antigen Complexes: T-Antigen Is Preferentially Associated with Early Replicating DNA Intermediates. Lois C. TACK AND MELVIN L. DEPAMPHILIS* ...... 281-295 Microinjected Simian Virus 40 cRNA Is Spliced, as Evidenced by Electron Microscopy. M. GRAESSMANN, A. GRAESSMANN,* AND H. WESTPHAL ...... 296-299 Genetic Mapping of a Mouse Chromosomal Locus Required for Mink Cell Focus-Forming Virus Replication. CHRISTINE A. KOZAK ...... 300-303 In Vitro DNA Synthesis by an a-Like DNA Polymerase Bound to Replicating Simian Virus 40 Chromosomes. M. ANWAR WAQAR, MARY Jo EVANS, JULIAN F. BURKE, YORIAKI TSUBOTA, M. JOAN PLUMMER, AND JOEL A. HUBERMAN* .... 304-308

Continued on following page Continued from prec eding page Relationship Between Synthesis and Cleavage of Poliovirus-Specific Proteins. ADRi A. M. THOMAS,* HARRY 0. VOORMA, AND ALBERT BOEYE ...... 309-313 Terminal Amino Acid Sequences and Proteolytic Cleavage Sites of Mouse Mammary Tumor Virus env Gene Products. Louis E. HENDERSON,* RAYMOND SOWDER, GARY SMYTHERS, AND STEPHEN OROSZLAN ...... 314-319 Characterization of Virus-Specific RNA Synthesized in Bovine Cells Infected with Bovine Viral Diarrhea Virus. A. F. PURCHIO,* RUBY LARSON, AND MARC S. COLLETT ...... 320-324 N-Acetylgalactosaminyltransferase Activity Involved in O-Glyco- sylation of Herpes Simplex Virus Type 1 Glycoproteins. FRANCA SERAFINI-CESSI,* FABio DALL'OLIO, MAURIZIA SCANNAVINI, FRANCO COSTANZO, AND GABRIELLA CAMPADELLI-FIUME ...... 325-329 Completion of the Gene Coding Assignments of SAl Rotavirus: Gene Products of Segments 7, 8, and 9. PHILLIP KANTHARIDIS,* MICHAEL L. DYALL-SMITH, AND IAN H. HOLMES ...... 330-334 Bacterial Viruses In Vivo Cleavage of Cytosine-Containing Bacteriophage T4 DNA to Genetically Distinct, Discretely Sized Fragments. KARIN CARLSON* AND JOHN S. WIBERG ...... 18-30 Involvement of Escherichia coli K-12 DNA Polymerase I in the Growth of Bacteriophage Mu. DANI L. MCBETH AND AUSTIN L. TAYLOR* ...... 149-156 The Bacteriophage P4 ot Gene Is the Structural Gene for Bacterio- phage P4-Induced RNA Polymerase. KATHLEEN J. BARRETT,* ALEKSANDRA BLINKOVA, AND GEORG ARNOLD ... 157-169 Enzymatic Construction and Selection of Bacteriophage G4 Mu- tants with Modifications of a DNA Secondary Structure in the J-F Intercistronic Region. UWE R. MULLER ...... 170-179 Mutations in the J-F Intercistronic Region of Bacteriophages XX174 and G4 Affect the Regulation of Gene Expression. MARTIN L. ROMANTSCHUK AND UWE R. MULLER* ...... 180-185 Role for the J-F Intercistronic Region of Bacteriophages (X174 and G4 in Stability of mRNA. MARIE N. HAYASHI, MASAKI HAYASHI,* AND UWE R. MULLER ...... 186-196 Insect Viruses Expression of Campoletis sonorensis Virus in the Parasitized Host, Heliothis virescens. Jo-ANN G. W. FLEMING, GARY W. BLISSARD, MAX D. SUMMERS,* AND S. BRADLEIGH VINSON . 74-78

* Asterisk refers to person to whom inquiries regarding the paper should be addressed.