Phytochemistry 176 (2020) 112402
Phytochemistry 176 (2020) 112402 Contents lists available at ScienceDirect Phytochemistry journal homepage: www.elsevier.com/locate/phytochem Metabolic variation in Cistus monspeliensis L. ecotypes correlated to their T plant-fungal interactions Luis Francisco Salomé-Abarcaa,1, Manuela Mandronea,b,1, Cinzia Sannac, Ferruccio Polib, ∗ Cees A.M.J.J. van der Hondeld, Peter G.L. Klinkhamere, Young Hae Choia,f, a Natural Products Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333, BE Leiden, the Netherlands b Department of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 42, 40126, Bologna, Italy c Department of Life and Environmental Sciences, University of Cagliari, Via Sant’Ignazio da Laconi 13, 09123, Cagliari, Italy d Department of Molecular Microbiology and Biotechnology, Leiden University, Institute of Biology Leiden, Leiden, the Netherlands e Plant Ecology and Phytochemistry, Institute of Biology, Leiden University, Sylviusweg 72, 2333, BE Leiden, the Netherlands f College of Pharmacy, Kyung Hee University, 02447 Seoul, Republic of Korea ARTICLE INFO ABSTRACT Keywords: The effect of environmental factors on the chemical composition of plants eventually resulting in plantgrowth Cistus monspeliensis regulation is an age-old issue in plant biology. Nowadays, the acceleration in changes in environmental con- Cistaceae ditions (e.g. global warming) can act as an incentive to investigate their correlation with metabolic changes. In Diterpenes this study, Cistus monspeliensis plants grown on the island of Sardinia (Italy) were used to explore the geo- Labdane graphical-mediated metabolic variation and its repercussion on plant-fungus interactions. Samples of different Clerodane ecotypes of C. monspeliensis were collected and chemically profiled by 1H NMR and HPTLC-based metabolomics Flavonoids Adaptation and the relationship between the variations of biological activity was examined by multivariate data analysis.
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