WEEKLY EPIDEMIOLOGICAL RECORD, No. 18,1 MAY 1992 • RELEVE EPIDEMIOLOGIQUE HEBDOMADAIRE, N' 1 8 ,1‘ MAI 1992

Evaluation of Certain Veterinary Drug Evaluation des résidus de certains médicaments Residues in Food vétérinaires dans les aliments Thirty-eighth Report of the Joint FAO/WHO Expert Committee on Food Trente-huitième rapport du Comité mixte FAO/OMS d'experts des Additifs Additives1 alimentaires1

This report presents the conclusions of a Joint FAO/WHO Ce rapport présente les conclusions d'un Comité mixte FAO/OMS Expert Committee convened to evaluate the safety of resi­ d'experts chargé d'évaluer l'innocuité des résidus de certains médi­ dues of certain veterinary drugs in food and to recommend caments vétérinaires dans les aliments et de recommander des maximum levels for such residues in food. concentrations maximales admissibles pour ces résidus. The first part of the report considers the application of La première partie du rapport envisage l'application, dans les safety factors to no-observed-effect levels for veterinary études toxicologiques, de facteurs de sécurité aux concentrations drugs in toxicological studies and the implications of phar­ sans effet observé des médicaments vétérinaires, et examine les macologically active residues, residues at the injection site effets des résidus pharmacologiquement actifs, les résidus au point in animal tissue, and withdrawal times for the setting of d'injection dans un tissu animal et les délais d'attente à prendre en Maximum Residue lim its for foods. considération pour fixer les limites maximales des résidus dans les aliments. A summary follows of the Committee's evaluations of Vient ensuite un résumé des évaluations toxicologiques et des toxicological and residue data on a variety of veterinary drugs: observations sur les résidus faites par le Comité au sujet de certains a p-adrenoceptor-blocking agent (carazolol), 3 anthel- médicaments vétérinaires: un bêta-bloquant (carazolol), 3 anthel- minthics (febantel, fenbendazole, and oxfendazole), 3 anti­ minthiques (fébantel, fenbendazone et oxfendazole), 3 antimicro­ microbial agents (spiramycin, sulfadimidine, and tylosin), biens (spiramydne, sulfadimidine, et tylosine), et 3 tranquillisants and 3 tranquillizers (azaperone, chlorpromazine, and pro- (azapérone, chlorpromazine et propionylpromazine). pionylpromazine). Annexed to the report are a summary of the Committee's On trouvera en annexe un résumé des recommandations du recommendations on these compounds, including Accept­ Comité sur ces composés avec les doses journalières admissibles et able Daily Intakes and Maximum Residue limits, a list of les limites maximales de résidus, une liste des informations com­ further information required or desired, details of pro­ plémentaires qu'il serait nécessaire ou souhaitable d'obtenir, des cedures for assessing the microbiological safety of anti­ détails sur les méthodes d'évaluation de la sécurité microbiologique microbial drugs in food, and a discussion of matters arising des antimicrobiens dans les aliments et l'examen de questions from the Fifth Session of the Codex Committee on Residues soulevées lors de la cinquième session du Comité du Codex sur les of Veterinary Drugs in Foods. résidus de médicaments vétérinaires dans les aliments.

1 Technical Report Sews, No. 815,1991; vi + 64 pages (available in English; 1 Séné de Rapports techniques N" 815,1991; vi + 64 pages (disponible en anglais et en French and Spanish in preparation); ISBN 92 4 120815 5; Swfr. 9.-/ français; version espagnole en préparation); ISBN 92 4 220815 9; Fr.s 9 .-/US 88,10 US §8 10 (in developing countries. Sw fr. 6 30), Order No. 1100815. (dans les pays en développement: Fr.s. 6,30); N" de commande 2100815.

Note on geographical areas Note sur les unités géographiques The form of presentation in the Weekly Epidemiological Record does not imply Il ne faudrait pas conclure de la présentation adoptée dons le Relevé épidémiologique heb­ official endorsementor acceptance by the Worid Health Organization of the status domadaire que l'Organisation mondiale de lo Santé admet ou reconnaît officiellement le or boundaries of the territories as listed or described. It has been adopted solely statut ou les limites des territoires mentionnés. Ce mode de présentation n'a d'outre objet for the purpose of providing a convenient geographical basis for the information que de donner un cadre géographique aux renseignements publiés. Lo même réserve vaut herein. The same quaMcation applies to all notes and explanations concerning également pour toutes les notes et explications relatives aux pays et territoires qui figurent the geographical units for which data are prowled. dans les tableaux.

Health administrations are reminded that under the provisions of Article 3 Il est rappelé aux administrations sanitaires qu'aux termes de I'ortide 3 du Règlement of the International Health Regulations they should notify the Organization by sanitoire international elles doivent adresser une notification à l'Organisation par télé­ telegram, fox or telex wiÊin 24 hours of being infoimed that the nrst case of a gramme, fax ou p télex dans les 24 heures, dès au'elles sont informées qu'un premier disease subject to the Regulations has occurred in their territory. The infected area cas d'une maladie soumise au Règlement a été signalé dans une zone de leur ressort. Dans should be notified within the subsequent 24 hours if not already communicated. les 24 heures qui suivent, elles adressent notification de la zone infectée si elle n'a pas encore été communiquée. In addition, they should notify the Organization by telegram, fox or telex En outre, elles doivent adresser une notification à l'Organisation, p télégramme, fax within 24 hours of being informed of an imported or transfened case of such a ou por télex dons les 24 heures, dès qu'elles sont informées d'un cas importé ou trans­ disease into a non-infected area including nil information available on the origin féré dans une zone norriafectée, y compris tous les renseignements disponibles sur l'origine of infection. de l'infection.

Infected areas as at 30 April 1992 Zones infectées au 30 avril 1992 For criteria used in compiling dus list, see No 5, p. 32 Les cnteres appliqués pour la enmpfannn fa cede liste sont publies A»™ le N“ 5, p 32 X - Newly reported areas X - Nouvelles mi» signals

Plague. Peste Antsirabe I I S P rif Mtarwanvo £ Prif. Bevanotany District Talata-Vohimena District Ambodiala District Analavory District Snanilyi»fwiana DlSttlCt Tsarasaotra District Africa • Afrique Ambohitsunanova District Anosibc Ifanja District Ambohanahasaa £ P r i f Fandnana S Prif Madagascar Ampasaianety District Remvohcra £ P rif Manandroy Di strier Fiadanana District Antananarivo Province Manaadona District Soavmandnam S. Prif Ambasura S. Prif, Fumaramsoa J £ P rif Soaoindrariny District Amharnasuna Centre Amhqrnmarma DlSOlCt Ambohidraavrw £ Prif. Mahatsinjo District Tsarofar District Tstroanomandtdjy S. Prif Ambohiznahazo District Atuanananoo-Avaradrano S Pref Ftanarantsoa II S Prif Vmaninkareaa Dismet Anisvunana Province Ambovombe Centre Ambatolampy S. Prêt AnvonmataoS Prif Andapa S Prif Andinn District Andftharannmairtift District Aitfosorobe S P rif Betafo £ Prif. Doaay District Anjoma N'Ankona District Fianaraxusoa H District Antananarivo S Prif. Alakamisy-AnanvatP District Ftanarantsoa Province Anjoma Navona District Manadnana S. Prif Antananarivo District Fanandnana S Prif Ambatcfinandrahana S. Prif. Ankazoambo District Mahujanga Province Antamfotsy S. Prif. Faratsiho S. P rif Ambondroousotrs District Ivato District Toamasma Province Antsirabe IS Prif Manjakandmna S. Prif Andrdambobitra District Ivony District Muramanga £ P rif

1 3 4 WEEKLY EPIDEMIOLOGICAL RECORD, No. U , 1 MAY 1992 • RELEVE EPIDEMIOLOGIQUE HEBDOMADAIRE, IM IL 1" MAI 1992

Tanzania, United Rep. of Bujumbura Provmce Tahom Departement Boyaca Department Areqmpa Department Tanzanie, Rép.«Uok de Bujumbura ^pnnriiggwnenr Tillabéry Département Caldas Department Ayacucho Department Tanga Begum Bururt Provmce Z m d e r D é p a r te m e n t Caqueta Intendency Cajamarca Department Lushoio District Makamba ArTnTM^iBsem^"r Nigeria • Nigéria Cattca Department Callao Province Tanga Distria Bnmnnp» Anmriiwwni«nr C e s a r D e p a r tm e n t Cuzco Department Abnqa State Guega Promue Chaco Department Huancavehca Department Zaire * Zaire Akualbom State Gitega Arrondissement Cordoba Department Huanuco Department Haul Zone Province Anambra State Mabsgt Administrative fam u m iw • P ampiwiill BaUCkt Star* Cundmamarca Department lea Department Gwgrra Department Provmce de l'Extréme-Nord Baidel State Junm Department Huüa Department La Libertad Department Americo* Amérique Diamare Departement Benue State M agdalena Department Lambayeque Department Logone-et-Chan Département B o m o S ta te Bolivia - Bolivie Mesa Department Mayo-Danai Departement Gongala State Lana Department La Paz Department Nonna Department Loreto Department Mayo-Sava Département ‘ In to S ta te Fraaz Tamayo Province Norte de Santander Department Madré de D m Department Mayo-Tsanaga Dépamrment K a d u n a Sud Yungas Provmce Qumtho Department Moquegua Department Provmce Lmorol K a n o S ta te Valle Grande Province Rnaralda Department Pasco Department Moungo Départanem Katsma State San Andres Intendency tira-rfl m Bn ÔI Woun Département Kxoara State Ptura Department San José del Gutnnare Department Puno Department Bahia State Provmce du Nord Logos State Santa Fe de Bogota Department San M oran Department Binunga Mumapio Benoué Département Niger State Santander Department Tacna Department Candeal Mumapm Prom ue de l'Ouest Ogun State < Sucre Department Tumbes Department Central Mumapio Haul Nkam Département O n d o S ta te Tolsma Department Ucayah Department Conceiçâo Mumapio Provmce du Sud O y o S ta te Valle Department Fora de Mumapio Ocean Département P la te a u Suriname Iraquara Mumapio Costa Rica Chad • Tchad Revers State M arowtjne District Irccê Mumapio Sokoto State San José Provmce Itaberaba Muruapto Batha Préfecture Venezuela Rwanda Jussara Mumapio B et Préfecture Aragua State Renrolindia Mumcipio Bütm e Préfecture Cyangugu Préfecture Azuay Provmce Carabobo State Riachào do Jacuipe Mumapio Chars Bagium u Prefecture G uenyi Prefecture B obtar Province Federal D iana Senbor do Bonfim Mumapio Guera Préfecture Sao Tome and Principe Cahar Provmce Tachra State Semaha Mumapio Kanem Préfecture Sâo Tomc-ct-Principe Carchi Provmce Z u h a S ta te Teofilandia Mumapio Lac Préfecture I-gmha District Chimborazo Province Paraiba State Logone Occidental Préfecture Sâo Tomé Cotopaxi Provmce Asia «Asie Araba Mumapio Logent Orientai Prefecture Tanzania, United Rep. of E l Oro Provmce RHiitnw • Bhnutfln Bans de S. Rosa Mumapio Njam ena Préfecture Tanzanie, Rép.-Unie de Esmeraldas Province Mongar Distna Cuban Mumapio OuaddaS Préfecture Arusha Regum Galapagos Province Pexpagatsd Dtstnq Okvedos Mumapio Tandple Préfecture Kikmanjaxo Regum Guayas Provmce Phnntshohng Distna Queimadas Mumapio Côte d’ivoire M a r a R eg u m Imbabura Province Punakha Distna Remigio Mumapio Département de POuest Mauara Regum Loja Provmce ■SgmHmpjnnglchar DtttTKt Solânea Mumapio Man Sous Préfecture Rukvta Region Las Run Promue Tashigang Distna M anabi Provmce Peru • Pérou Ghana Tanga Regum Thimphu District Morona Provmce Cajamarca Department Accra Région Togo Pastaza Province India ■ Inde Chata Province Accra Dismet Golfe Distna Pichmcha Provmce Andhra Pradesh State L lam a District Greater Accra District Kioto Distna Suatmbtos Provmce Hyderabad Distna Miracosta Distna Central Région Kozah Distna Tungurahua Provmce Vjsafchgpamam DlSDlCt Tocmoche District Upper E au Région Lacs Distna Zamora-Chmcittpe Provmce Assam State San M iguel Provmce Volta Région Ogou Distna Delhi Territory Nanchoc Dismct Sotouboua D um a £1 Salvador Guinea • Guinée Central Region Gujarat State San Gregono District Conakry Province Vo Dismct Haryana State San Miguel District Yoto Distna M etropolitan Region Forécariab Préfecture Occidental Regum Karnataka (Mysore) State San Pablo Province Bangalore D istna Kenya Uganda * Ouganda Oriental Region San Louis District (Area not - Zone mm (Area not specified - Zone non Paracentral Region Btdar Distna Putra Deportment précisée) nhitraAirp Distna précisée) Guatemala Ayabaca Province Gulburga Distna Canales Dismct Liberia «Libéria Zaire • Zaire Alta Verapaz Department H aut Zaire Province Hassan Disma Lagunas Dismct Bong County Baja Verapaz Department Kolar Dum a Montera District Montsenado County Revu Provmce Chquanula Department Shaba Provmce Mandya Duma Paunas Dismct Malawi Chxmahenango Department Raichar Distna Sapülica District Central Region Zambia * E l Progreso Department Tumkur Distna Escumda Department Suyo District Lilongwe District Central Province Kerala State Guatemala Department Huancabamba Province Southern Region T malca M adhya Pradesh State Huehueienango Department G. de la Fromm Distna Copperbek Provmce M aharashtra State Izabal Department Canchaquc Distna Luapula Provmce Akola Duma Huancabamba Dismct Kayes Cerde Northern Provmce Junapa Department Amrawaa D um a Pesât Department Puara Province Kouhkom Begum Southern Provmce Nagpur Dum a Las Lomas Dismct Nara Cerde Quetzahenango Department Nan dad Dum a Amenai* Amérique Quiche Department Mniiwtania m Maiiijhml» Osmanabad D um a Asie «Asie Retaihuleu Department Nouakchott Dismct Àiy n fin a — Ai»gMiriara Parbham Dutria Viet Nam Formosa Province Sacasepéquez Department Pune D um a I r e R é g io n San M aras Department Gia-Loi-Càng Turn Province Hodh el Qhargrn X Jujuy Provmce Sangli D um a Lâm Dâng Provmce S a lta . P ro v m c e Santa Rosa Department Thane Dutria 2 e R eg u m Saida Department PkuKhan Province M ampur State Hodh el Ghntbi Belize Suckitepéquez Department Punjab State 3 e R é g io n Toledo D istrict Totomcapân Department Cholera • Choléra Tamil Nadu State Assaba et Gmdimakha Bolivia • Bolivie Zacapa Department 4 e R é g io n Anna District Africa • Afrique X Bern Department Gorgol Honduras Chingleput D uma Angola Chuqutsaca Department R é g io n Choluieca Department Madras Dutria Bengo Province Cochabamba Department B a k o u VaBe Department Madurai Dum a Benguela Provmce La Paz Department 6 e R é g io n North Aicot D um a Huambo Provmce Oruro Department Mexico «Mexique Trarza Campeche State Pudukkonai Duma Huda Provmce Pbtoa Department Thanjavur Duma Kuando-Kubango Provmce Mozambique Santa Cruz Department Chapas State Cabo Delgado Provmce Cohma State Timchirapalh Duma Kunene Province Tanja Department Tirundvdh Duma Kuanza-Norte Province Chiure District D istrito federal Pcxoba City Brazil • Brésil Guanajuato State Vellore Dum a Kxuanza-Sui Province Amapâ State Gaza Provmce Guerrero State Vilbpuram Duma Luanda Provmce Amazonas Slate U ttar Pradesh State Luanda, Cap. Chokwe Distna Hidalgo State Manmhda State West Bengal State M alanga Province Xai-Xai Dum a Mexico State M ato Grosso State Çalei^rra Natmbe Provmce M aputo Provmce Mtchoacan State P a ra S ta te Utge Provmce Boane Distna Morelos State lnH«nr«la • jfndnnéri* Paraiba State Zatre Province Manhira Distna Oaxaca State J a v a B a r a t P ro v m c e Maputo City Pernambuco Srntf Puebla State Tangcrang Regency Ri»nin • Rwiin R u Grande do Norte State Matuturae Distna Tabasco State Kalimantan Seiatan Provusce Département de l'Atlantique Moamba Distna Rondâma State Tamauhpas State Banjar Regency S. Prêt d'Allada Wamaarha DiKmrr fiwift • n>ai Veracruz State Baajannasia Muninpaluy Cire de Cotonou Sofala Provmce Antofagasta Provmce Yucatan State Hulu Sungai Seiatan Regency S Prêt de ToflEo Bora City Bernardo O'Htggms Province ytiratfrn Stsits Hulu Sungai Tengah Regency Département de lAiacora Zambezta Provmce Coquanbo Provmce Nicaragua Hulu Sungai Utara Regency Département de Borgou Mopaa Distna Los Lagos Provmce Léon Department Tabalong Regency Département de Mono Namacutra Distna Osomo Panama M aluku Province Département de Zou Nicoadala Distna Santiago Provmce Colon Province Maluku Tengah Regency Burkina Faso Qudimane Distna Tarapaca Provmce Danen Province Sumatera Barat Provmce Botdgou Provmce Niger fjilnmKj* • rolmw^ie Panama Province Solok Regency Burundi D iffa Département Amazonas Department Peru «Pérou Iraq Bubanza Provmce Dosso Département Anhoquia Department Amazonas Department Al-Basra Govemorate Bubanza Arrondissement M aradt Departement Adanuco Department Ancash Department Al-Anbar Govemorate Cibuoke Arrondissement Nutm ey Département Bohvttr Department Apunmac Department Al-Mathna Govemorate

135 WEEKLY EPIDEMIOLOGICAL RECORD, No. IS , 1 MAY 1992 • RELEVE EPIDEMIOLOGIQUE HEBDOMADAIRE, N118,1* MA11992

Al-Najef Govemorate Bauch State Damolândia Mumapio £1 Doncello Mumapio Monzon Distnct Al-Qadisiya Govemorate Bendel State Formosa M u m a p io San Vicente de Caguan P Luyando Dismct Arbü Govemorate Berne State Goias Velho Mumdpio Muniapio Rupa Rupa Distnct Babil Govemorate Cross River State Mara Rosa Mumapio Casanare Jntendenaa M arahon Province Baghdad Govemorate Kaàuna State Nova Cruras Mumapio Haro Corozal Mumapio CholonDistna Dohuk Govemorate Ktoara State Planalnna Mumapio Tamara Mumapio Jurtm Department Dyala Govemorate Lagos State Santa Cruz Mumapio Yopal Muniapio Chanchamayo Province Karbala Govemorate Niger State M aranhaS State Cesar Department Chanchamayo Distna Megan Govemorate O g u n S ta te Grajau Mumapio Valledupar Muniapio Perene Distna Nineveh Govemorate O n d e S m h » Chaco Department Lago da Pedra Municipio San Tjiis Sevaro Disma Salah El-Din Govemorate O y o S ta te Montes Altos M u m a p io Rio Sudo Muniapio Viloc Dismct Sulaimaxuyah Govemorate Plateau State M ato Grosso State Cundmamarca Department Maya Mumdpio Saapo Province Tamim Govemorate Sudan * Soudan Antômo Joào Muniapio Guaviare Iruendencia Covinali Disma Tikar Govemorate Temtory South of 12° N Diamannno Mumapio Jardim Mumapio Miraflores Mumapio Mazaman Disma Wasit Govemorate Territoire situé au sud San Juan del Guaviare Pangoa Disma M alaysia • Malaftele du 12° N Nova Marrnga Mumapio Mumapio Pichanali Disma S a b a h Piaado de Castro Mumapio Zaire • Zaïre Meta Intendenaa Tawau District SiHrolânHia M u m apio Rio Negro Disma Temtory North of 10° S. Cabuyaro Mumapio S a r a w a k Sinope Mumapio Rio Tambo Distna Territoire situe au nord La Pnmavera Mumapio Simunjan District Teranos Muruapio Saapo Distna du 10° S. M inas Gerais State San Carlo de Guaroa Loreto Department Nepal • Népal Bonfinopolis Mumapio Mumapio Ucayali Province Baitadi District Ameilco • Amérique Francisco Dumont Mumapio Villavicenao Mumapio Cantamana District Khatmandu Distnct Vista Hennosa Muniapio Bolivia • Bolivie Mirabels Mumapio Purus Distna N one de Santander Department Viet Nam Bera Department Paracatu Mumapio M adré de Dias Department Bmh Tn Then Province Unai Muniapio Cucuta Mumapio Balhvian Province Tibu Mumapio M anu Province Nghia Bmh Provence Itenez Province P a r a S ta te Madré de Dios Distna Cucuta Intendenaa Phu Khành Province Cochabamba Department Alenquer Mumapio Manu Disma Almeinm Mumdpio Toledo Muniapio Ayopayo Province Tambopata Province Europe Alramira M umapio Putumayo Intendenaa Carrasco Province Puerto Aias Muniapio lnamban Disma Ukraine Chapare Province Araguaia Muniapio S a n ta n d e r D e p a r tm e n t Las Piedras Distna Manupole La Pas Department Faro Muniapio ~Rnrflwur>anga M nmrapin Tambopata Distna Nicolaev Région Larecaja Province Monte Alegre Mumdpio Prainha Mumapio flim itarra M nmnpirr Puno Department Odssskaya Region Munllo Province Fi Carmen Mumapio Nor Yungas Province RendenySo Muniapio Sandta Province Vichada Department Ornnuni Province Sâo Domingos do Capim San Juan del Oro Disma Yellow fever • Fièvre jaune Puerto Trujillo Muniapio Sud Yungas Province Mumapio San Roman Distna Âfrico • Afrique Santa Crus Department Sen. José Porfino Mumapio Ecuador * Ftp»*»***»» Vikabamba Disma Andres Ibaiiez Province TaÜandia Mumapio Morona-SanUago Province San Alartm Department Angola Cordillera Province Tacurui Mumdpio Napo Province HuaSaga Province Bengo Province Xinguara Muniapio Huznayacu District Luanda Province Florida Province Bellavista Distna GuneiTez Province Rondama Saa» Pastaza Province Saposoa Distna Cameroon • Cameroun Ichüo Province Cacoal Mumapio Zamora-Ckmchpc Province Lamas Province Province de l'Extrême-Nord Rorcama Territory Brazil* Brésil Peru «Pérou Lamas Distna Mayo Sava Département R onfim Mumapio Ayacucho Department Tahalazos Disma Mayo Tsanaga Département Amapa Temtory flafimpft Milium Mumapio Macapâ Muniapio Huaraa Province M anscal Coterez Province Maloca Caju Mumapto Gambia • Gambie Amazonas State San Jose SannHana District Campanil la Disma Upper River Division Hanntflma MuUlClCpiO ftiiomhia • Colombie Cusco Department Sou M artin Province Guinea * Guinée Joào Figuoxedo Mumapio Annoqma Department La Convention Province Juan Guetta Disma Siguin Région Manaquui Mumdpao Anon Mumdpio Echarate Distnct Sauce Duma Manaus Miuuripin Taraza Municipio Kitam Disma Mali Tocache Provenu Maraâ Mumapio Yondo Muniapio Maranura Distnct La Polvora Distna Kayes Region Araucabuendenaa Sama Ana Distnct Nova Olinda do Norte Nuevo Progreso Distna Municipio Arauca Municipio Huaruico Department Tocache Distna Kauhkoro Région Novo Airaô Mumapio Saravena Muniapio HuamaHes Province Dioïla Cercle Uchiza Disma Tefe Mumapio Boyaca Department Monzou District Cercle Urucara Mumapio Chira Mumapio Leonaa Prado Province Ucayah Department Kaü Cercle Goias State Pucrta Boyaca Mumapio Aloma Robles District Coronet Panda Province Cercle Alio Paraiso Mumdpio Caqueta Imendencia Aucayacu District Callena Disma Nigeria • Nigéria Reia Vista Mumapio Belen de los Andaquies J.C Castelk) Disma Padre Abad Province Anambra Situe Czuapowa Mumcip» Municipio Leonao Prado District Padre Abad Dismct

*^1“ "• I* ■*- * 3-.SLS3 î u h z î j c T x m u u m

Notifications received from 24 to 30 April 1992 Notifications reçues du 24 au 30 avril 1992 C - cases, D - deaths,... - data not yet received, C - cas, D - décès,... - données non encore disponibles, î - imported, r - revised, s - suspect î - importe, r - révisé, s - suspect

Choiera • Choléra C D Africa • Afrique Brazil - Brésil 5-18JV C D Kenya 15 ÛI-16.IV ...... 680 13 Costa Bica 12-25.IV ...... 3{2i) 0 Americu • Amérique El Salvador 12-25 IV C D ...... 343 0 Bolivia - Bolivie 3-18 IV Peru - Pérou 22-28.IH ...... 951 15 ...... 10 827 66

Telex:415416 Fnx:78800 11 Telex: 415416 Fax: 788 00 11 (Attention EPIDNATI0NS for notifications of diseases subject to the regulations) [A l'attention d'EPIONATIONS concernant les notifications des maladies soumises au règlement) Automatic telex reply service: Service automatique de réponse par télex: Telex 415768 Geneva followed by ZCZC ENGL for reply in English Télex 415768 Genève suivi de ZCZC FRAN pour une réponse en fronçais Price of the Weekly Epidemiological Record Prix du Relevé épidémiologique hebdomadaire Annual subscription Sw. fr. 170- Abonnement annuel Fr. s. 170.- 8000 5 92 ISSN 0049-8114 Printed m Switzerland

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