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PDF Output of CLIC (Clustering by Inferred Co-Expression) PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 47 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 47. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Col6a2 Col6a1 Col6a3 Bgn Sspn Crispld2 Aimp1 Cav2 Bloc1s6 Stx2 Nrsn1 Ap1g2 Yipf2 Pcsk1 Gnas Nptx1 Ap3s1 Nts Prg2 1500015O10Rik Tmem168 Plekhf2 Yipf1 Ovgp1 Bloc1s3 Shh Pcsk2 Galnt15 Syt13 Rab11a Nrsn2 Aph1b Vgf Exoc3l Cnst Astl Cdk16 B230216G23Rik Yipf3 Ap1ar Cpa3 Bloc1s5 Rab3d Hck Pigr 0610007P14Rik Myrip Col6a2 Col6a1 Col6a3 CEM 1 (611 datasets) Bgn Sspn Crispld2 Aimp1 Cav2 Bloc1s6 Stx2 Nrsn1 Ap1g2 Yipf2 Pcsk1 Gnas Nptx1 Ap3s1 Nts Prg2 1500015O10Rik Tmem168 Plekhf2 Yipf1 Ovgp1 Bloc1s3 Shh Pcsk2 Singletons Galnt15 Syt13 Rab11a Nrsn2 Aph1b Vgf Exoc3l Cnst Astl Cdk16 B230216G23Rik Yipf3 Ap1ar Cpa3 Bloc1s5 Rab3d Hck Pigr 0610007P14Rik Myrip Symbol Num ofCEMGenes:6.Predicted183.SelectedDatasets:611.Strength:11.5 CEM 1,Geneset"[G]transportvesicle",Page1 Tmem119 Serpinh1 Adamts2 Serpinf1 Crispld2 Col12a1 Efemp2 Leprel2 Ccdc80 Fkbp10 Col3a1 Col5a1 Col1a1 Col5a2 Col1a2 Col6a3 Col6a1 Col6a2 Col4a1 Col4a2 Pcolce Pdgfrb Lama2 Lama4 Olfml3 Cdh11 Aebp1 Cd248 Igfbp7 Fkbp7 Thbs2 Mxra8 Mmp2 Sparc Postn Bicc1 Fbln5 Loxl2 Rcn3 Sspn Fstl1 Nid1 Lhfp Ppic Lum Mgp Bgn Lox Dpt Islr 0.0 1.0 GSE16925 [15] GSE35785 [10] GSE13106 [10] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE18907 [12] GSE44339 [14] GSE6383 [6] GSE14395 [24] GSE39391 [21] GSE51608 [6] GSE14354 [6] GSE40368 [10] GSE56542 [8] GSE19979 [6] GSE4193 [8] GSE53299 [6] GSE5038 [9] GSE12956 [10] GSE8044 [6] GSE12618 [6] GSE27848 [16] GSE41759 [14] GSE54349 [6] GSE40156 [42] GSE44101 [6] GSE41342 [26] GSE42601 [6] GSE26299 [108] GSE5671 [18] GSE7694 [12] GSE45820 [6] GSE23845 [15] GSE15267 [8] GSE7810 [9] GSE9013 [12] GSE13302 [30] GSE10556 [6] GSE13874 [14] GSE34618 [7] GSE11898 [9] GSE18281 [33] GSE11759 [6] GSE37191 [12] GSE48790 [8] GSE54207 [9] GSE25029 [56] GSE28277 [10] GSE18534 [15] GSE27987 [31] GSE34552 [10] GSE6210 [12] GSE16691 [12] GSE42008 [6] GSE6589 [11] GSE5037 [18] GSE35091 [11] GSE47772 [24] GSE36229 [14] GSE35396 [24] GSE9400 [8] GSE8025 [21] GSE31244 [6] GSE10813 [12] GSE35961 [12] GSE49346 [6] GSE42753 [6] GSE24625 [12] GSE26290 [12] GSE47777 [8] GSE28664 [17] GSE13044 [59] GSE13526 [6] GSE32334 [19] GSE53403 [16] GSE13408 [14] GSE39984 [18] GSE6881 [10] GSE18660 [10] GSE23408 [39] GSE27630 [8] GSE29485 [12] GSE27932 [14] GSE7069 [8] GSE32277 [33] GSE24793 [8] GSE20577 [12] GSE52550 [12] GSE22925 [14] GSE40856 [8] GSE27261 [8] GSE7342 [12] GSE27546 [51] GSE15580 [14] GSE50824 [19] GSE29813 [18] GSE15794 [6] GSE15772 [8] GSE28389 [20] GSE29766 [40] GSE17462 [8] GSE59672 [12] GSE20177 [14] GSE7020 [8] GSE13563 [6] GSE9098 [12] GSE52101 [17] GSE24295 [7] GSE8024 [8] GSE32966 [24] GSE11148 [6] GSE33134 [31] GSE30855 [6] GSE18135 [18] GSE27568 [16] GSE58307 [20] GSE11443 [6] GSE38257 [14] GSE32095 [24] GSE32937 [8] GSE29975 [6] GSE5011 [10] GSE22371 [6] GSE34091 [8] GSE31431 [34] GSE27713 [7] GSE23598 [8] GSE30852 [6] GSE43779 [6] GSE18586 [9] GSE53951 [10] GSE5245 [16] GSE10965 [8] GSE18587 [9] GSE7196 [6] GSE33471 [12] GSE12498 [12] GSE44175 [18] GSE8788 [6] GSE5333 [16] GSE4695 [6] GSE15401 [18] GSE51686 [9] GSE10113 [12] GSE16496 [102] GSE9123 [8] GSE33726 [48] GSE38224 [12] GSE45968 [6] GSE14481 [12] GSE9044 [6] GSE55162 [8] GSE24276 [6] GSE22989 [10] GSE9711 [6] GSE19793 [32] CEM+ CEM GSE15155 [12] GSE51213 [16] GSE51483 [45] GSE21576 [10] GSE52474 [154] GSE35322 [20] 0.0 GSE14088 [9] GSE22841 [12] GSE4230 [8] Scale ofaveragePearsoncorrelations GSE19194 [14] GSE18742 [13] GSE6540 [12] GSE31106 [18] GSE42049 [8] GSE51628 [15] 0.2 GSE6867 [6] GSE36415 [14] GSE51432 [15] GSE17373 [24] GSE50439 [15] GSE30561 [6] GSE51108 [6] GSE31013 [12] GSE27302 [16] 0.4 GSE9735 [9] GSE22251 [9] GSE56777 [8] GSE59437 [30] GSE17797 [19] GSE34279 [30] GSE9892 [12] GSE30863 [20] GSE20523 [17] 0.6 GSE31598 [12] GSE53986 [16] GSE22307 [23] GSE46211 [18] GSE13963 [15] GSE13148 [10] GSE16790 [18] GSE15729 [15] GSE17817 [6] 0.8 GSE18395 [8] GSE33860 [28] GSE33308 [10] GSE32598 [11] Score 59.90 59.93 60.05 60.47 60.73 62.20 63.21 63.80 66.16 67.96 69.43 69.75 71.99 73.39 74.07 76.41 77.08 77.93 78.02 78.03 79.22 79.75 81.29 82.82 87.62 88.06 89.67 90.12 91.69 99.88 100.50 101.60 102.94 104.83 110.87 116.01 118.66 123.72 125.23 147.40 158.25 166.57 168.73 187.35 1.0 Notes Symbol Num ofCEMGenes:6.Predicted183.SelectedDatasets:611.Strength:11.5 CEM 1,Geneset"[G]transportvesicle",Page2 Fam114a1 Adamts12 Tmem45a Prkcdbp Col15a1 Col16a1 Olfml2b Emilin1 Tgfb1i1 Fkbp14 Gpr153 Gpr124 Mmp23 B3gnt9 Scara3 Smoc2 Pmp22 Kdelr3 Lrrc17 Scarf2 Copz2 Svep1 Fkbp9 Pdgfrl Mfap4 Mfap5 Matn2 Ednra Srpx2 Ltbp3 Tgfb3 Tagln Loxl3 Crtap Htra3 Gpx7 Aspn Cd34 Pxdn Cav1 Reck Srpx Myl9 Rhoj Ctsk Slit3 Ogn Gsn Tnc Fn1 0.0 1.0 GSE16925 [15] GSE35785 [10] GSE13106 [10] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE18907 [12] GSE44339 [14] GSE6383 [6] GSE14395 [24] GSE39391 [21] GSE51608 [6] GSE14354 [6] GSE40368 [10] GSE56542 [8] GSE19979 [6] GSE4193 [8] GSE53299 [6] GSE5038 [9] GSE12956 [10] GSE8044 [6] GSE12618 [6] GSE27848 [16] GSE41759 [14] GSE54349 [6] GSE40156 [42] GSE44101 [6] GSE41342 [26] GSE42601 [6] GSE26299 [108] GSE5671 [18] GSE7694 [12] GSE45820 [6] GSE23845 [15] GSE15267 [8] GSE7810 [9] GSE9013 [12] GSE13302 [30] GSE10556 [6] GSE13874 [14] GSE34618 [7] GSE11898 [9] GSE18281 [33] GSE11759 [6] GSE37191 [12] GSE48790 [8] GSE54207 [9] GSE25029 [56] GSE28277 [10] GSE18534 [15] GSE27987 [31] GSE34552 [10] GSE6210 [12] GSE16691 [12] GSE42008 [6] GSE6589 [11] GSE5037 [18] GSE35091 [11] GSE47772 [24] GSE36229 [14] GSE35396 [24] GSE9400 [8] GSE8025 [21] GSE31244 [6] GSE10813 [12] GSE35961 [12] GSE49346 [6] GSE42753 [6] GSE24625 [12] GSE26290 [12] GSE47777 [8] GSE28664 [17] GSE13044 [59] GSE13526 [6] GSE32334 [19] GSE53403 [16] GSE13408 [14] GSE39984 [18] GSE6881 [10] GSE18660 [10] GSE23408 [39] GSE27630 [8] GSE29485 [12] GSE27932 [14] GSE7069 [8] GSE32277 [33] GSE24793 [8] GSE20577 [12] GSE52550 [12] GSE22925 [14] GSE40856 [8] GSE27261 [8] GSE7342 [12] GSE27546 [51] GSE15580 [14] GSE50824 [19] GSE29813 [18] GSE15794 [6] GSE15772 [8] GSE28389 [20] GSE29766 [40] GSE17462 [8] GSE59672 [12] GSE20177 [14] GSE7020 [8] GSE13563 [6] GSE9098 [12] GSE52101 [17] GSE24295 [7] GSE8024 [8] GSE32966 [24] GSE11148 [6] GSE33134 [31] GSE30855 [6] GSE18135 [18] GSE27568 [16] GSE58307 [20] GSE11443 [6] GSE38257 [14] GSE32095 [24] GSE32937 [8] GSE29975 [6] GSE5011 [10] GSE22371 [6] GSE34091 [8] GSE31431 [34] GSE27713 [7] GSE23598 [8] GSE30852 [6] GSE43779 [6] GSE18586 [9] GSE53951 [10] GSE5245 [16] GSE10965 [8] GSE18587 [9] GSE7196 [6] GSE33471 [12] GSE12498 [12] GSE44175 [18] GSE8788 [6] GSE5333 [16] GSE4695 [6] GSE15401 [18] GSE51686 [9] GSE10113 [12] GSE16496 [102] GSE9123 [8] GSE33726 [48] GSE38224 [12] GSE45968 [6] GSE14481 [12] GSE9044 [6] GSE55162 [8] GSE24276 [6] GSE22989 [10] GSE9711 [6] GSE19793 [32] CEM+ CEM GSE15155 [12] GSE51213 [16] GSE51483 [45] GSE21576 [10] GSE52474 [154] GSE35322 [20] 0.0 GSE14088 [9] GSE22841 [12] GSE4230 [8] Scale ofaveragePearsoncorrelations GSE19194 [14] GSE18742 [13] GSE6540 [12] GSE31106 [18] GSE42049 [8] GSE51628 [15] 0.2 GSE6867 [6] GSE36415 [14] GSE51432 [15] GSE17373 [24] GSE50439 [15] GSE30561 [6] GSE51108 [6] GSE31013 [12] GSE27302 [16] 0.4 GSE9735 [9] GSE22251 [9] GSE56777 [8] GSE59437 [30] GSE17797 [19] GSE34279 [30] GSE9892 [12] GSE30863 [20] GSE20523 [17] 0.6 GSE31598 [12] GSE53986 [16] GSE22307 [23] GSE46211 [18] GSE13963 [15] GSE13148 [10] GSE16790 [18] GSE15729 [15] GSE17817 [6] 0.8 GSE18395 [8] GSE33860 [28] GSE33308 [10] GSE32598 [11] Score 29.05 29.57 30.00 30.03 30.47 30.73 30.81 30.98 31.52 32.47 32.66 35.86 36.63 36.63 37.04 37.10 38.04 38.71 38.86 39.24 39.40 39.80 41.23 41.90 42.01 43.15 43.80 44.04 44.68 44.78 45.38 45.55 45.82 45.91 46.33 47.35 50.55 50.77 52.13 52.81 52.87 53.46 53.57 53.62 55.73 56.29 56.64 57.19 58.04 58.95 1.0 Notes Symbol Num ofCEMGenes:6.Predicted183.SelectedDatasets:611.Strength:11.5 CEM 1,Geneset"[G]transportvesicle",Page3 Fam198b Serping1 Adamts5 Colec12 Col14a1 C1qtnf2 Creb3l1 Sparcl1 Cyp1b1 Efemp1 Casp12 Fndc3b Myadm Cmtm3 Col5a3 Kdelc2 Lepre1 Lamb1 Lgals1 Lamc1 Cspg4 Abca9 Anxa5 Vstm4 Wwtr1 Igfbp6 Eva1b Wisp1 Mfap2 Actg2 Emp3 Ltbp2 Fmod Itm2a Loxl1 Htra1 Gpx8 Gas1 Ehd2 Ptgis Dkk3 Pkd2 Tns1 Nbl1 Calu Dsel Ctgf Vim Fap Axl 0.0 1.0 GSE16925 [15] GSE35785 [10] GSE13106 [10] Only showingfirst200datasets-Seetxtoutputforfulldetails.
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