DOCSLIB.ORG

Asbmb Goes to China

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Asbmb Goes to China ASBMB ANNOUNCES 2008 AWARD WINNERS September 2007 ASBMB GOES TO CHINA American Society for Biochemistry and Molecular Biology Scientists helping scientists… It costs no more to choose the very best for your custom peptides and antibodies… Ac-C T P R Q I pS F N F K-OH All peptides are made in our laboratories 1461.640 with the most rigorous QC in the industry – pSFNFK-H3PO4 -98 623.245 We sequence every purified -H PO peptide we manufacture! 3 4 PhD scientists with over 70 years of 623.0 626.5 combined experience in Chemistry, Mass 293.141 72 Cell Biology and Immunology 1218.599 1169.510 1347.658 536.784 740.405 809.426 1317.591 6 246.072 499.227 972.531 400 600 800 1000 1200 1400 Mass Complete antibody protocols and no hidden charges. Phosphospecific antibody experts! Custom peptides up to 100 AAs in length and at purities up to >98%. Peptides for epitope mapping as low as $4/AA. Modifications include phosphorylated amino acids, dye-labeling, cyclic peptides, and peptides with stable isotopes. Experience for yourself why research scientists around the world trust 21st Century Biochemicals for their custom peptides and antibodies! Come speak with our scientists at: Biomedical Research Equipment and Supplies Exhibit at Harvard Medical School Sept. 19 – 20 Society for Neuroscience, San Diego, CA Nov. 3 – 7 American Society for Cell Biology, Washington, DC Dec. 1 – 5 www.21stcenturybio.com 260 Cedar Hill Street, Marlboro, MA 01752 Made in the P: 508.303.8222 Toll-free: 877.217.8238 F: 508.303.8333 E: [email protected] U.S.A. contents SEPTEMBER 2007 ON THE COVER: A delegation of seven representa- tives from ASBMB recently visited society news Beijing, Guangzhou, and Shanghai 2 President’s Message where they met with Chinese sci- entists, students, and members of 6 Washington Update the Society’s counterpart in China. 7 New JBC Minireview 12 Compendium on Interferons 10 Retrospective: Daniel E. Koshland Jr. special interest 12 ASBMB Delegation Tours China 14 Early Medical Research Funding and the Evolution of Modern American Biochemistry 2008 meeting overview 16 Systems Biology: a shared goal with diverse views 18 The Diverse Aspects of Protein Synthesis and Degradation 20 A Renaissance for Metabolism Research compendium. 7 22 RNA: From Atom to Organism 23 ASBMB Taps 8 Scientists and 1 Politician for Top Awards science focus 27 Maurice Swanson: Finding New Cures for Muscular Dystrophy 30 Matthias Mann: Using Proteomics to Understand Protein Interactions departments 4 News from the Hill 8 Member Spotlight 24 Career Insights 26 Education and Training 32 BioBits resources 34 For Your Lab 35 Career Opportunities 36 Scientific Meeting Calendar e transcription cttor two-step. 32 September 2007 ASBMB Today 1 president’smessage A monthly publication of The American Society for Biochemistry and Molecular Biology Peer Review Front Officers Heidi E. Hamm President and Center Gregory A. Petsko President-Elect BY HEIDI HAMM Mark A. Lemmon Secretary Merle S. Olson Treasurer Council Members Alan Hall Kuan-Teh Jeang Suzanne R. Pfeffer Linda J. Pike John D. Scott Joan A. Steitz Kevin Struhl James A. Wells t’s great to be back from a very Groups (IRGs). (More information is Ex-Officio Members Iproductive and interesting trip to given at cms.csr.nih.gov/AboutCSR/ Ellis Bell China with our ASBMB delegation. We OpenHouses.htm.) The open house on Chair, Education and Professional met our goals of establishing a closer Biomolecular IRGs, which is particu- Development Committee Laurie S. Kaguni relationship with Chinese scientists in larly relevant to ASBMB, will be held on Chair, Meeting Committee biochemistry and molecular biology, December 18. George Hill and we were delighted with the warm The Panel on Scientific Boundaries Chair, Minority Affairs Committee Kendall J. Blumer and enthusiastic welcome we received. for Review, headed by Bruce Alberts, Anna Marie Pyle I am sure you have been hearing undertook the latest reorganization Co-chairs, 2008 Program Committee about the many calls for information of study sections. I have been work- Mary J. C. Hendrix Chair, Public Affairs Advisory Committee from the National Institutes of Health ing closely with Bruce for a couple of Robert E. Rhoads (NIH) on many topics. One which is years on the issue of how to influence Chair, Publications Committee dear to our hearts is peer review. It’s the CSR to have more ongoing input Herbert Tabor Editor, JBC good to see that the NIH is making a from extramural scientists on how study Ralph A. Bradshaw major effort to examine the peer review sections are functioning. This ongoing A. L. Burlingame process. This critical reexamination fo interaction has led to a proposal for the Co-editors, MCP Edward A. Dennis the peer review system has been a high two societies to work together to provide Editor, JLR priority of ASBMB, prompted by the our input to the CSR. Thus, the two ASBMB Today crisis in funding and resultant doubling societies will jointly analyze the makeup Editorial Advisory Board of NIH grant applications over recent and scope of the study sections that are Alex Toker years. A key reason for this reassessment of most interest to the two societies, Chair is to be sure the system is operating as it determine whether there is sufficient Mike Autry Greg P. Bertenshaw Craig E. Cameron A. Stephen Dahms was meant to after the last major over- breadth, expertise, and balance between Irwin Fridovich Richard W. Hanson haul instigated by the Panel on Scientific basic and clinical investigators, etc. Our Elizabeth A. Komives Bettie Sue Masters Luke A. O’Neill Boundaries for Review almost 7 years analysis will be provided to the CSR at Duanqing Pei Carol C. Shoulders ago. Of course, we hope that completely this open house. If you are willing to be Robert D. Wells new ideas will emerge from this reex- involved in this analysis, please let me ASBMB Today amination to help us overcome the real or Mary Hendrix, chair of the Public Nicole Kresge Editor crisis in peer review that has resulted Affairs Advisory Committee, know of [email protected] from the lack of investment in biomedi- your interest! In particular, we need Pat Pages Science Writer [email protected] cal research over the last 5 years. ASBMB members who have served on Nancy J. Rodnan Director of Publications A number of activities to assess these study sections recently, as they are [email protected] Barbara Gordon Executive Director peer review are underway. Toni Scarpa, the real experts on how well the study [email protected] director of the Center for Scientific sections are working. Magazine design & production: Amy Phifer Review (CSR), announced a series of Additionally, a Working Group of For information on advertising contact open houses to give the extramural the NIH Advisory Committee to the FASEB AdNet at 800-433-2732 ext. 7157 or community a chance to voice their views Director, focusing on a review of the 301-634-7157, or E-mail [email protected]. on the quality and expertise of various current peer review system at NIH, met study sections and Integrated Review in Washington, D.C. on July 30 to hear www.asbmb.org September 2007 comments from the scientific com- Working Group co-chairs Lawrence We hope all of you with an inter- munity. ASBMB President-Elect Greg Tabak, director of the National Institute est in the NIH peer review system will Petsko delivered ASBMB’s comments, of Dental and Craniofacial Research, bookmark this site and visit it regularly which covered 4 main points: and Keith Yamamoto, University of to keep abreast of what is going on. Oversight of study sections should California, San Francisco, noted in The Working Group will be accepting be ongoing. The Center for Scientific their July 12 letter to the commu- comments from concerned members Review must monitor the IRGs and nity about the group that “With the of the biomedical research community; study sections to ensure that they are increasing breadth and complexity of the NIH also currently has a request functioning as they should, and make science, along with the rising number for information on the NIH System to changes as appropriate based on feed- of research grant applications, we are Support Biomedical and Behavioral back from both members of the study Research and Peer Review (grants.nih. sections and those whose proposals are gov/grants/guide/notice-files/NOT- reviewed there. Critical OD-07-084.html). Senior researchers should continue reexamination In his opening remarks, Yama- to serve on study sections. ASBMB moto noted that there had been many also recommended that assistant of the peer review changes in peer review since he became professors not serve on study sections. involved in the mid-1980s. In 1987, Petsko recommended that senior system is a high there were only 1,800 people serving researchers be compelled to serve on priority of ASBMB on study sections. Now, that figure has study sections, similar to serving on grown by an order of magnitude— juries when called upon. As he noted, 18,000 scientists are currently serving. “holding a federal grant is a privilege, taking a comprehensive look at our Furthermore, the nature of science is not a right,” and thus those who hold review process to ensure its continued different; the scope of applications is them should be expected to pay back strength for applicants and reviewers much broader than 20 years ago. the system by study section service if alike. We would like you to participate Yamamoto went on to note that called upon. in this discussion.” NIH Director Elias the review process must evolve and Study section membership must fit Zerhouni was in attendance the entire adapt to these changes.
Load more

Recommended publications
  • AT BERKELEY MCB SPRING 1998 Newsletter for Members and Alumni of the Department of Molecular & Cell Biology at the University of California, Berkeley
    AT BERKELEY MCB SPRING 1998 Newsletter for Members and Alumni of the Department of Molecular & Cell Biology at the University of California, Berkeley Graduate Admissions Committee, under the We were all greatly saddened by the loss Message from academic and administrative leadership of of our dear friend and colleague, Marian David Drubin and Eileen Bell, has enrolled a Koshland (see page 4-5). Marian represented new class of 45 students, 10 of whom have the best of citizenship and scholarship here at the Chair independent fellowships (NSF, HHMI, Cal and in the larger academic arena. She DOD, and University). Congratulations to continued to teach, supervise research, and I hope you enjoy our inaugural edition of the the faculty and student members of the serve as Head of the Graduate Affairs Unit MCB at Berkeley Newsletter. MCB was born Graduate Admissions Committee and the even as she labored in declining health. I must almost ten years ago, and we have grown to Graduate Affairs Unit staff for another out- recount a personal anecdote concerning my such an extent that I felt it was necessary to standing year. Although it is premature to initial encounter with Marian. The Koshland’s create a vehicle of communication connecting make a public announcement, we have every invited me to a party at their home shortly the Divisions of our far-flung enterprise. In indication that our faculty recruitment for after I arrived in Berkeley in 1976. The addition, we have trained a generation of stu- 1998-99 will also be a smash- Biochemistry Department had dents and fellows who have gone on to their ing success.
    [Show full text]
  • Of Animals, Nature and People.[Student's Guide.] Preparing
    DOCUMENT RESUME ED-23'0 377 SE 041 574 i . AUTHOR Iozzi, Louis A.; And Others TITLE Of Animals,-Nature and People. (S:udent's Guide.] Preparing for Tomorrow's World. 4 IN5TITUTION . Rutgers, The State Univ., New Brunswick, N.J. Center . for Coastal and Environmental Studies. SPONS AGENCY New Jersey State Dept. of Education, Trenton. PUB DATE 80 - , NOTE 132p.; For related documents, see SE 61 564-585. A complete catalog of the multi-media packages making , up this program is contained in,SE 041 585. , AVAILABLE FROMSOPRIS WEST, Inc., 1120 Delaware Ave., Longmont, CO . 80501 (Complete multi-media module, including stddent materials, $95; replacement student worksheets, $2). PUB TYPE Guides- Classroom Use -,Materials (For Learner) (051) EDRS PRICE MF01 Plus Postage. PC Not Available froM'EDRS. DESCRIPTORS Animals; Critical ThinkingrDecision Making; *Environmental Education; *Futures (of Society); High Schools; Interdisciplinary Approach; Learning Activities;. Moral Development; *Moral Issues; *tatural Resources; Physical Environffient; *Problem Solving; Role Plaking; Science Education; Secondary SChool Science; Social Studies; Student'Attitudes; Technology; Wildlife IDENTIFIERS. Dilemma Discussion Approach; *Environmental Ethic; . Preparing for Tomorrows'World PrograM; *Science and Society ABSTRACT Developing an awareness of the need to evolim an environmental ethic is the intent of this module, designed for the . senior high school level (grades 10-11)% The module is divided into two sections. Section 1 contains a series of dilemma/discussion activities raising issues regarding hulnan behavior toward, animals and the natural environment. Dilemmas.are-brief stories posing a critical decision to be made by a mainscharacter: This decision.revolves aroUnd conflicts between two .or more moral/ethical'isstes (as .
    [Show full text]
  • And Ludwik Rajchman (1881-1965)
    Macfadyen, David (2014) The genealogy of WHO and UNICEF and the intersecting careers of Melville Mackenzie (1889-1972) and Ludwik Rajchman (1881-1965). MD thesis. http://theses.gla.ac.uk/5625/ Copyright and moral rights for this thesis are retained by the author A copy can be downloaded for personal non-commercial research or study, without prior permission or charge This thesis cannot be reproduced or quoted extensively from without first obtaining permission in writing from the Author The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the Author When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given Glasgow Theses Service http://theses.gla.ac.uk/ [email protected] The Genealogy of WHO and UNICEF and the Intersecting Careers of Melville Mackenzie (1889-1972) and Ludwik Rajchman (1881-1965) David Macfadyen MB ChB (Glasg), MSc (London), FRCP Edin. A thesis submitted to the University of Glasgow for the degree of Doctor of Medicine Centre for the History of Medicine College of Medical, Veterinary and Life Sciences University of Glasgow September 2014 Page 1 of 323 Summary This thesis traces the antecedents of the World Health Organization (WHO) back to 1920, when a new type of international health organization emerged following the establishment of the League of Nations, one that was based on collective action by nation-states. The 1946 Constitution of WHO specifies two prime functions for the Organization – technical assistance to countries and cooperation with governments to strengthen national health services.
    [Show full text]
  • 72 New Members Chosen by Academy Search
    72 New Members Chosen by Academy Search: Subscribe to our FREE e- newsletter! NATIONAL ACADEMY OF SCIENCES NATIONAL ACADEMY OF ENGINEERING INSTITUTE OF MEDICINE NATIONAL RESEARCH COUNCIL June 18, 2004 Current Operating Status About the National Academies Current Projects News Office Publications For Congress Members' Site Marian Koshland Science Museum Giving to the National Date: April 20, 2004 Academies Contact: Office of News and Public Information Directories 202-334-2138; e-mail <[email protected]> Contact Us Site Map FOR IMMEDIATE RELEASE Career Links 72 New Members Chosen by Academy Employment Internships WASHINGTON -- The National Academy of Sciences today announced the Fellowships & Postdoc election of 72 new members and 18 foreign associates from 13 countries in Career Guides recognition of their distinguished and continuing achievements in original research. News Links The election was held this morning during the business session of the 141st annual News Archive meeting of the Academy. Election to membership in the Academy is considered Reports & Events one of the highest honors that can be accorded a U.S. scientist or engineer. Those Top News elected today bring the total number of active members to 1,949. Science in the Headlines The National Academies Op- Foreign associates are nonvoting members of the Academy, with citizenship Ed Service outside the United States. Today's election brings the total number of foreign associates to 351. The National Academy of Sciences is a private organization of scientists and engineers dedicated to the furtherance of science and its use for the general welfare. It was established in 1863 by a congressional act of incorporation, signed by Abraham Lincoln, which calls on the Academy to act as an official adviser to the federal government, upon request, in any matter of science or technology.
    [Show full text]
  • Marian Elliot Koshland
    NATIONAL ACADEMY OF SCIENCES MARIAN ELLIOTT KOSHLAND 1 9 2 1 — 1 9 9 7 A Biographical Memoir by R UTH LEVY GUYER Any opinions expressed in this memoir are those of the author and do not necessarily reflect the views of the National Academy of Sciences. Biographical Memoir COPYRIGHT 2007 NATIONAL ACADEMY OF SCIENCES WASHINGTON, D.C. Photo Courtesy Marian Kosshland Science Museum MARIAN ELLIOTT KOSHLAND October 25, 1921–October 28, 1997 BY RUTH LEVY GUYER ARIAN ELLIOTT KOSHLAND WAS AN eminent immunologist. MShe was spirited, practical, insightful, and inventive, and she had tremendous integrity, energy, and smarts. She was also a caring and generous person. I was fortunate to be one of her graduate students at the University of California at Berkeley in the early 1970s. Marian had become a professor in the bacteriology and immunology department at Berkeley shortly before I joined her group. Her laboratory was in the old Life Sciences Build- ing near the (in)famous eucalyptus grove, a campus landmark redolent of medicinal oils and site of commonplace conversa- tions, licit and illicit trysts, and spurned lovers’ fist fights. Marian’s laboratory was large and classic: Rows of tall, stately black benches spanned much of the width of the room, and at the back near the windows that looked out onto the building’s courtyard was a hulking rectangular conference table. That table was where we—the four graduate students, the postdoc from Lausanne, the two technicians, and Mar- ian—gathered every day at lunchtime to eat and to talk about J chain—the joining protein of immunoglobulin molecules that Marian & Co.
    [Show full text]
  • Ion Gresser 1928–2019
    obituary Ion Gresser 1928–2019 on Gresser, a virologist who transformed of another interferon pathfinder, Charles understanding of the roles of interferons, Chany, at the Hôpital St. Vincent de Paul, Imay be best remembered for showing and soon thereafter establishing his own that in mice, interferon-α (IFN-α) can laboratory at the Institut de Recherches produce acute and chronic disease. At the Scientifiques sur le Cancer in Villejuif, time Gresser began these studies, interferon outside Paris. Eventually, Gresser ended up was considered to be a selective antiviral spending decades at the Villejuif laboratory, substance, harmless to uninfected cells and and it was there that he conducted all of organisms, and there was no indication that his many original studies for which he cytokines would play a role in pathogenesis. became known. Although he retired from That belief was shattered with the 1975 his position at Villejuif many years ago, Nature publication with the simple title he continued to publish reviews, as well “Lethality of interferon preparations for as original research in collaboration with newborn mice.” others. His very last paper, co-authored with Gresser subsequently demonstrated Pierre Lebon, Yanick Crow and Jean-Laurent that antibodies to IFN-α can protect young More surprising at the time was the first Casanova, appeared in March of this year, mice from death caused by infection with demonstration, by Gresser and colleagues only weeks before his passing. lymphocytic choriomeningitis virus. This in 1973, that IFN-α enhances the expression Arguably, the most important study can be considered a stepping-stone of histocompatibility antigens and modifies contribution of Gresser and his colleagues for the therapeutic application of antibodies the surface of uninfected cells, and that was the demonstration of harmful effects to cytokines in the treatment of human it has other immunomodulatory actions.
    [Show full text]
  • Human Genetic Basis of Interindividual Variability in the Course of Infection
    Human genetic basis of interindividual variability in the course of infection Jean-Laurent Casanovaa,b,c,d,e,1 aSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065; bHoward Hughes Medical Institute, New York, NY 10065; cLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Inserm U1163, Necker Hospital for Sick Children, 75015 Paris, France; dImagine Institute, Paris Descartes University, 75015 Paris, France; and ePediatric Hematology and Immunology Unit, Assistance Publique–Hôpitaux de Paris, Necker Hospital for Sick Children, 75015 Paris, France This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2015. Contributed by Jean-Laurent Casanova, November 2, 2015 (sent for review September 15, 2015; reviewed by Max D. Cooper and Richard A. Gatti) The key problem in human infectious diseases was posed at the immunity (cell-autonomous mechanisms), then of cell-extrinsic turn of the 20th century: their pathogenesis. For almost any given innate immunity (phagocytosis of pathogens by professional cells), virus, bacterium, fungus, or parasite, life-threatening clinical disease and, finally, of cell-extrinsic adaptive immunity (somatic di- develops in only a small minority of infected individuals. Solving this versification of antigen-specific cells). Understanding the patho- infection enigma is important clinically, for diagnosis, prognosis, genesis of infectious diseases, particularly
    [Show full text]
  • Oralhisttransretro00maririch.Pdf
    University of California Berkeley of Regional Oral History Office University California The Bancroft Library Berkeley, California MARIAN E. KOSHLAND (1921-1997): RETROSPECTIVES ON A LIFE IN ACADEMIC SCIENCE, FAMILY, AND COMMUNITY ACTIVITIES James P. Allison Anne H. Good Catherine P. Koshland Daniel E. Koshland, Jr. Douglas E. Koshland James M. Koshland Hugh O. McDevitt Gail Koshland Wachtel Introduction by Daniel E. Koshland, Jr. Interviews Conducted by Sally Smith Hughes in 1999 and 2000 Copyright 2003 by The Regents of the University of California Since 1954 the Regional Oral History Office has been interviewing leading participants in or well-placed witnesses to major events in the development of northern California, the West, and the nation. Oral history is a method of collecting historical information through tape-recorded interviews between a narrator with firsthand knowledge of historically significant events and a well-informed interviewer, with the goal of preserving substantive additions to the historical record. The tape recording is transcribed, lightly edited for continuity and clarity, and reviewed by the interviewee. The corrected manuscript is indexed, bound with photographs and illustrative materials, and placed in The Bancroft Library at the University of California, Berkeley, and in other research collections for scholarly use. Because it is primary material, oral history is not intended to present the final, verified, or complete narrative of events. It is a spoken account, offered by the interviewee in response to questioning, and as such it is reflective, partisan, deeply involved, and irreplaceable. * * * * * if * * * * * * * * ** ** * * * ** * ** * * * * ** * * * * All uses of this manuscript are covered by a legal agreement between The Regents of the University of California and Daniel Koshland, December 14, 1998; Hugh McDevitt dated November 23, 1999; James M.
    [Show full text]
  • In Memoriam Marian Koshland 1921
    In Memoriam Marian Koshland 1921−1997 Jim Allison J Immunol 1998; 161:545-546; ; This information is current as http://www.jimmunol.org/content/161/2/545 of September 25, 2021. Downloaded from Why The JI? Submit online. • Rapid Reviews! 30 days* from submission to initial decision • No Triage! Every submission reviewed by practicing scientists http://www.jimmunol.org/ • Fast Publication! 4 weeks from acceptance to publication *average Subscription Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription Permissions Submit copyright permission requests at: by guest on September 25, 2021 http://www.aai.org/About/Publications/JI/copyright.html Email Alerts Receive free email-alerts when new articles cite this article. Sign up at: http://jimmunol.org/alerts The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 Copyright © 1998 by The American Association of Immunologists All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. In Memoriam Marian Koshland 1921–1997 It would not be at all an exaggeration to say that Marian Koshland’s career was spectacular. She made very important con- tributions to our field in each and every decade for the past half century. As a graduate student at the University of Chicago in the 1940s Bunny, as she was known, worked on a vaccine for Asiatic cholera. This work not only demonstrated the importance of mu- cosal antibodies in immunity but also led to her lifelong interest in the structure and origin of antibodies.
    [Show full text]
  • In Memoriam Marian Koshland 1921
    In Memoriam Marian Koshland 1921−1997 Jim Allison J Immunol 1998; 161:545-546; ; This information is current as http://www.jimmunol.org/content/161/2/545 of September 27, 2021. Downloaded from Why The JI? Submit online. • Rapid Reviews! 30 days* from submission to initial decision • No Triage! Every submission reviewed by practicing scientists http://www.jimmunol.org/ • Fast Publication! 4 weeks from acceptance to publication *average Subscription Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription Permissions Submit copyright permission requests at: by guest on September 27, 2021 http://www.aai.org/About/Publications/JI/copyright.html Email Alerts Receive free email-alerts when new articles cite this article. Sign up at: http://jimmunol.org/alerts The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 Copyright © 1998 by The American Association of Immunologists All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. In Memoriam Marian Koshland 1921–1997 It would not be at all an exaggeration to say that Marian Koshland’s career was spectacular. She made very important con- tributions to our field in each and every decade for the past half century. As a graduate student at the University of Chicago in the 1940s Bunny, as she was known, worked on a vaccine for Asiatic cholera. This work not only demonstrated the importance of mu- cosal antibodies in immunity but also led to her lifelong interest in the structure and origin of antibodies.
    [Show full text]
  • Biological Activity and Therapeutic Applications of Intracellular Interferon Gamma and Interferon Gamma Mimetic Peptides
    BIOLOGICAL ACTIVITY AND THERAPEUTIC APPLICATIONS OF INTRACELLULAR INTERFERON GAMMA AND INTERFERON GAMMA MIMETIC PEPTIDES By MARGI ANNE BURKHART A THESIS PRESENTED TO THE GRADUATE SCHOOL OF THE UNIVERSITY OF FLORIDA IN PARTIAL FULLFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE UNIVERSITY OF FLORIDA 2003 As a granddaughter, that has been denied the privilege of celebrating the accomplishments of adulthood with my grandparents, I would like to dedicate this achievement to them as a small way of honoring their lasting influence on my life. My Mom has jokingly told me in the past that I have done some crazy things causing my grandparents to roll in their graves. I know that this accomplishment will put that rolling to rest and allow them to once more brag about their granddaughter among the heavens. To my Grandma, Grandpa, Granny, and Tabo I would like to say, “I miss each of you dearly, and thank you for watching over me.” ACKNOWLEDGMENTS While working to complete my master’s I have been privileged to have a strong support system. The success that I have had in my research and master’s education was implicitly dependent on the following individuals. First, I would like to thank the Department of Microbiology and Cell Science for giving me the opportunity to explore my interests in research and for providing a challenging and interesting curriculum. I would also like to thank my thesis committee including Dr. Howard Johnson, Dr. Edward Hoffmann, and Dr. Peter Kima for their kind words and guidance during the writing process. More specifically, I would like to thank Dr.
    [Show full text]
  • I Regional Oral History Office University of California the Bancroft
    i Regional Oral History Office University of California The Bancroft Library Berkeley, California DANIEL E. KOSHLAND, JR. SCIENCE, ACADEMIC SERVICE, PHILANTHROPY Supplementary interview with Robert Tjian Interviews conducted by Sally Smith Hughes in 1998 and 1999 Copyright © 2011 by The Regents of the University of California ii Since 1954 the Regional Oral History Office has been interviewing leading participants in or well-placed witnesses to major events in the development of Northern California, the West, and the nation. Oral History is a method of collecting historical information through tape-recorded interviews between a narrator with firsthand knowledge of historically significant events and a well-informed interviewer, with the goal of preserving substantive additions to the historical record. The tape recording is transcribed, lightly edited for continuity and clarity, and reviewed by the interviewee. The corrected manuscript is bound with photographs and illustrative materials and placed in The Bancroft Library at the University of California, Berkeley, and in other research collections for scholarly use. Because it is primary material, oral history is not intended to present the final, verified, or complete narrative of events. It is a spoken account, offered by the interviewee in response to questioning, and as such it is reflective, partisan, deeply involved, and irreplaceable. ********************************* All uses of this manuscript are covered by a legal agreement between The Regents of the University of California and Daniel E. Koshland, Jr., dated December 14, 1998. The manuscript is thereby made available for research purposes. All literary rights in the manuscript, including the right to publish, are reserved to The Bancroft Library of the University of California, Berkeley.
    [Show full text]