Supplemental Content

Appendix Table 1. List of drugs and drug classes

Alprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, estazolam, flurazepam, halazepam, Benzodiazepenes lorazepam, midazolam, oxazepam, prazepam, quazepam, temazepam, triazolam Antidepressants SSRI Citalopram, escitalopram, paroxetine, fluoxetine, fluvoxamine, sertraline SNRI Desvenlafaxine, duloxetine, levomilnacipran, milnacipran, tofenacin, venlafaxine SMS Vilazodone, vortioxetine SARI Etoperidone, trazodone, nefazodone NRI Reboxetine, viloxazine Amitriptyline, butriptyline, clomipramine, desipramine, dosulepin, imipramine, iprindole, lofepramine, TCAs melitracen, nortriptyline, protriptyline, trimipramine, opipramol, tianeptine TeCAs Amoxapine, maprotiline, mianserin, mirtazapine, setiptiline MAOIs Isocarboxazid, phenelzine, tranylcypromine, selegiline, metralindole, moclobemide, pirlindole, toloxatone Antipsychotics Chlorpromazine, thioridazine, mesoridazine, levomepromazine, loxapine, molindone, perphenazine, typical thiothixene, trifluoperazine, haloperidol, fluphenazine, droperidol, zuclopenthixol, prochlorperazine Amisulpride, aripiprazole, asenapine, blonanserine, clotiapine, clozapine, iloperidone, lurasidone, atypical mosapramine, olanzapine, paliperidone, perospirone, quetiapine, remoxipride, risperidone, sertindole, sulpiride, ziprasidone, zotepine Antiasthma Medications bronchodilators Salmeterol, metaproterenol, terbutaline, albuterol, ipratropium, formoterol, levalbuterol ,pirbuterol, Fluticasone, flunisolide, ciclesonide, mometasone, triamcinolone, prednisone, budesonide, corticosteroids beclomethasone, leukotriene Zafirlukast, montelukast, zileuton inhibitors Other Theophylline, omalizumab Key: SSRI=selective serotonin reuptake inhibitor; SNRI=serotonin/norepinephrine reuptake inhibitor; SMS=serotonin modulator/stimulator; SARI=serotonin antagonist/reuptake inhibitor; NRI=norepinephrine reuptake inhibitor; TCA=tricyclic antidepressant; TeCA=tetracyclic antidepressant; MAOI=monamine oxidase inhibitor

Appendix Table 1. List of drugs and drug classes (cont.)

Antihypertensives Loop diuretics Bumetanide, ethacrynic acid, furosemide, torsemide Epitizide, hydrochlorothiazide, chlorothiazide, Thiazide Diuretics bendroflumethiazide, indapamide, chlorthalidone, metolazone, polythiazide Potassium sparing Diuretics Amiloride, triamterene, spironolactone Atenolol, metoprolol, nadolol, nebivolol, oxprenolol, pindolol, Beta Blockers propranolol, timolol Doxazosin, phentolamine, indoramin, phenoxybenzamine, Alpha Blockers prazosin, terazosin, tolazoline Mixed Alpha/Beta Blockers Bucindolol, carvedilol, labetalol Amlodipine, clinidipine, felodipine, isradipine, lercanidipine, Calcium Channel Blockers levamlodipine, nicardipine, nifedipine, nimodipine, nitrendipine, diltiazem, verapamil Captopril, enalapril, fosinopril, lisinopril, perindopril, quinapril, Ace inhibitors ramipril, trandolapril, benazepril, moexipril Candesartan, eprosartan, irbesartan, losartan, olmesartan, ARBs telmisartan, valsartan Aldosterone antagonists Eplenerone, spironolactone Alpha 2 agonists Clonidine, guanabenz, guanfacine, methyldopa, moxonidine Hydralazine, guanethidine, mecamyalamine, reserpine, Miscellaneous minoxidil, deserpidine, aliskiren Antidiabetes Medications insulin Glyburide, glimepiride, glipizide, tolbutamide, acetohexamide, sulfonylureas tolazamide, chlorpropamide, gliclazide, gliquidone biguanides metformin alpha-glucosidase Inhibitors Acarbose, miglitol, voglibose meglitinides Repaglinide, nateglinide thiazolidinediones Pioglitzone, rosiglitazone