Program and Papers on New Research
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PROGRAM AND PAPERS ON NEW RESEARCH IN SUMMARY FORM THE ONE HUNDRED AND FORTY-FIFTH ANNUAL MEETING OF THE AMERICAN PSYCHIATRIC ASSOCIATION WASHINGTON, DC May 2-7, 1992 Papers presented at New Research Sessions are not automatically the property of the American Journal of Psychiatry. Authors are free to submit them to the American Journal of Psychiatry, the Journal of Hospital & Community Psychiatry, or another publication of their choice. SUBCOMMITTEE ON NEW RESEARCH OF THE SCIENTIFIC PROGRAM COMMITTEE Allan Tasman, M.D., Chairperson Craig N. Karson, M.D. Scientific Program Committee Little Rock, AR Louisville, KY Susan J. Fiester, M.D., Chairperson Jeffrey A. Lieberman, M.D. New Research Subcommittee Glen Oaks, NY Nashua, NH Raymond Cohen, M.D. Philip R. Muskin, M.D. Cincinnati,OH New York, NY Outside Reviewers for the New Research Program Nancy C. Andreasen, M.D. Robert M. Post, M.D. Wade H. Berrettini, M.D. William Z. Potter, M.D. Richard l. Borison, M.D. Frederic M. Quitkin, M.D. Gabrielle A. Carlson, M.D. Murray A. Raskind, M.D. Glen C. Davis, M.D. Stephen G. Rayport, M.D. Abby J. Fyer, M.D. Peter P. Roy-Byrne, M.D. Elliott S. Gershon, M.D. Charles A. Shamoian, M.D. Ira D. Glick, M.D. Larry J. Siever, M.D. Judith H. Gold, M.D. Andrew E. Skodol, M.D. Jack M. Gorman, M.D. Robert l. Spitzer, M.D. Katherine A. Halmi, M.D. Michael J. Stanley, M.D. Dilip V. Jeste, M.D. Marvin Stein, M.D. Donald F. Klein, M.D. James J. Strain, M.D. Joel E. Kleinman, M.D. Trey Sunderland, M.D. Donald S. Kornfeld, M.D. James W. Thompson, M.D. Michael R. Liebowitz, M.D. Thomas W. Uhde, M.D. Markku I. Linnoila, M.D. Fred R. Volkmar, M.D. Robert W. McCarley, M. D. B. Timothy Walsh, M.D. John M. Morihisa, M.D. Daniel R. Weinberger, M.D. Charles B. Nemeroff, M.D. George E. Woody, M.D. Charles P. O'Brien, M.D. Stuart C. Yudofsky, M.D. David Pickar, M. D. NEW~ RESEARCH Monday, May 4, 1992, 9:00 a.m.-10:30 a.m. New Research 1-Poster Session-Hall 0, Level 1, Convention Center YOUNG INVESTIGATORS' POSTER SESSION Moderator: Harold Alan Pincus, M.D. NR1 Information Processing Effect on Saccadic Reaction Time in Schizophrenia Douglas M. Berger, M.D., Shinnichi Nezu, M.D., Tomie Iga, B.S., Takashi Hosaka, M.D., Seiro Nakamura, M.D. NR2 Schizophrenia After Prenatal Exposure to Famine Ezra S. Susser, M.D., Lin P. Shang, Ph.D. NR3 Depression in First-Episode Schizophrenia Amy R. Koreen, M.D., Jeffrey A. Lieberman, M.D., Samuel C. Siris, M.D., Miranda Chakos, M.D., Jose Alvir, Dr. P.H., David I. Mayerhoff, M.D. NR4 Plasma HVA in First-Episode Schizophrenia Amy R. Koreen, M.D., Jeffrey A. Lieberman, M.D., Jose Alvir, Dr. P.H., David I. Mayerhoff, M.D., Antony Loebel, M.D., Miranda Chakos, M.D., Thomas Cooper, M.A. NR5 Schizophrenia: Correlated Onset of Comorbid Symptoms James M. Russell, M.D., Lee N. Robins, Ph.D., John P. Rice, Ph.D. NR6 Study of Relapse in Medication Compliant Schizophrenics Sandra Steingard, M.D., Krishna R. Khambampati, M.D., Maureen Allen, M.P.H. NR7 Delayed Effects of CRH and ACTH on Dopamine in Man Joel A. Posener, M.D., Joseph J. SChildkraut, M.D., Gordon H. Williams, M.D., Melinda S. Salomon, Ph.D., Nancy L. McHale, B.S., Alan F. Schatzberg, M.D. NRB Comorbidity in First-Episode Psychosis Stephen M. Strakowski, M.D., Mauricio Tohen, M.D., Andrew L. Stoll, M.D., Gianni L. Faedda, M.D., Pierre V. Mayer, M.D., Meridith L. Kolbrener, B.A., Daniel C. Goodwin NR9 Neuroimaging in Relatives of Schizophrenics Jeremy M. Silverman, Ph.D., Richard S.E. Keefe, Ph.D., Miklos F. Losonczy, M.D., Richard C. Mohs, Ph.D., Larry J. Siever, M.D., Kenneth L. Davis, M.D. NR10 In Vivo Proton Magnetic Resonance Spectroscopy in Never Treated Schizophrenics Jeff A. Stanley, M.Sc., Peter C. Williamson, M.D., Dick J. Drost, Ph.D., Tom Carr, M.D., Jane Rylett, Ph.D., Harold Merskey, D.M. NR11 Executive Impairment in Schizophrenia and Old Age Don R. Royall, M.D., Roderick Mahurin, Ph.D., Janet True, M.D., Brent Anderson, M.S., A. Miller, M.D. NR12 Adjuvant to Neuroleptics in Chronic Schizophrenia Pierre-Michel N Llorca, Marc A. Wolf, Thierry C. Bougerol, Christophe Lancon, Jean Claude Scotto NR13 Subgroups of Schizophrenics Responding to Adjuvant Treatment Pierre-Michel N Llorca, Thierry C. Bougerol, Marc A. Wolf, Christophe Lancon, Jean Claude Scotto NR14 Interleukin-1 and Interleukin-2 in the CSF of Schizophrenic Subjects Rifaat S. EI-Mallakh, M.D., Richard Jed Wyatt, M.D. 1 NR15 Medical Education: Computer Assisted Patient Education T. Bradley Tanner, M.D., Stuart Gitlow, M.D. NR16 The Longitudinal Importance of Expressed Emotion Suzanne King, Ph.D. NR17 Remoxipride in the Treatment of Schizophrenia Sanford Herman, M.D" Mark Weilgus, Ph.D., Carol Hermann, M.D., Andrea Berman, Ph.D., Kathleen O'Connor, B.A., John Herrera, Ph.D. NR18 Biological Analysis in Schizophrenic Patients Felicidad Rodriguez, M.D., Jesus Ezcurra, M.D. NR19 Cingulate Gyrus in Schizophrenia Versus Controls J. Thomas Noga, M.D., Elizabeth Aylward, Ph.D., Godfrey D. Pearlson, M.D. NR20 Prolactin Decrease and Response to Haloperidol Howard H.J. Chang, M.D., Alan I. Green, M.D., Roger A. Boshes, M.D., Mohammed Y. Alam, M.D., Joseph J. Schildkraut, M.D. NR21 Clozapine Versus Haldol in Schizophrenia: A PET Study Daniel Z. Press, B.A., Karen Faith Berman, M.D., Llewellyn B. Bigelow, M.D., Thomas Noga, M.D., Jill L. Ostrem, B.A., James Gold, Ph.D., Daniel R. Weinberger, M.D. NR22 Planum Temporal in Schizophrenia: A Magnetic Resonance Study Alessandro Rossi, Antonio Serio, M.D., Paolo Stratta, M.D., Concetta Petruzzi, M.D., Giovanni Schiazza, M.D., Massimo Casacchia, M.D. NR23 Integrating Psychosocial Treatment on an Inpatient Schizophrenia Research Unit: A Model for Multidisciplinary Psychoeducation Ellen Lukens, C.S.W., Kay D. Gimmestad, B.S., Helle Thorning, M.S.W., Ann Feinstein, OTR, Helen Deustch, R.N., Barbara Angell, R.N. NR24 Information Processing Deficits in Psychoses Esther F. Rabinowicz, Ph.D., Lewis A. Opler, M.D., David R. Owen, Ph.D., Raymond A. Knight, Ph.D. NR25 Factor Structure of the Neurological Evaluation Scale in Schizophrenia Laurence P. Karper, M.D., Morris Bell, Ph.D., Paul Lysaker, Ph.D., Joseph Goulet, M.S., John P. Seibyl, M.D., Joseph P. Erdos, M.D., Louise Brenner, M.S.N., John H. Krystal, M.D. NR26 Clozapine and Slow Wave Sleep in Schizophrenia Jon F. Chaffee, M.D., Steven G. Potkin, M.D., Joseph Wu, M.D. NR27 Heterogeneity in Serotonin Response in Chronic Schizophrenia Ad itayanjee , M.D., Jean-Pierre Lindenmayer, M.D., Sandra Grochowski, B.A., N. Bark, M.D., N. Moynihan, B.S.N. NR28 Comparison of Paranoid and Schizoid Personalities Mark Fulton, M.D., George Winokur, M.D. NR29 Abnormal Laterality in Parents and Schizophrenics Ellen M. Smith, M.D., Nancy Docherty, Ph.D., Bruce Wexler, M.D. NR30 PET in Frontal Head Injury and Striatal Metabolism Stephen Lottenberg, M.D., Nicole Theuvenet; Michelle Solano, Ronald M. Ruff, Ph.D., Jill Stanley, Monte S. Buchsbaum, M.D. NR31 Dopamine Effects on Hippocampal N-Methyl-D-Aspartate Responses Stephen J. Schertzer, M.D., Liang Zhang, M.D., Peter L. Carlen, M.D. 2 NR32 Hypoxia Improves Human Cognitive Function Thomas E. Schlaepfer, M.D. NR33 Effects of Adinazolam and N-Desmethyl Adinazolam Karon Dawkins, M.D., Robert P. Irwin, M.D., Richard L. Hauger, M.D., Joseph C. Fleishaker, Ph.D., William Z. Potter, M.D. NR34 Ictal EEG Effects of ECT Stimulus Intensity Andrew D. Krystal, M.D., Richard D. Weiner, M.D., Pamela K. Smith, Rebekka Arias, C. Edward Coffey, M.D. NR35 Schizotypy and Right Hemisphere Function in Mescaline-Induced Psychosis Godehard Oepen, M.D., Matthias Funfgeld, Anne Harrington, Ph.D., Gordon Claridge, Ph.D., Hanno Botsch, M.D. NR36 Fine Motor Performance in Schizophrenia Jay M. Griffith, M.D., Lawrence E. Adler, M.D., Robert Freedman, M.D. NR37 Pharmacodynamic Response to Intravenous Idazoxan Robert C. Risinger, M.D., Mark E. Schmidt, M.D., Ivan N. Mefford, Ph.D., William Z. Potter, M.D. NR38 Relationship of Low Baseline TSH to TRH Response Deborah Deas-Nesmith, M.D., William Carson, M.D., Shannon Little, M.D., Raymond Anton, M.D. NR39 Ratings of Aggression in Autistic Children Nilda M. Gonzalez, M.D., Monique Ernst, M.D., Jana Signe, BA, Magda Campbell, M.D., Joan Welkowitz, Ph.D. NR40 Malignant Catatonia: Sequelae and Treatment Kemuel L. Philbrick, M.D., Teresa A. Rummans, M.D. NR41 The Immunological Profile of Patient's with Alzheimer's Disease Jerzy W. Leszek, M.D., August Wasik, M.D., Barbara Siesak, Ph.D. NR42 MR Interuncal Distance in Alzheimer's and Parkinson's Disease Bridget Early, MA, Rodrigo Escalona, M.D., William M. McDonald, M.D., P. Murali Doraiswamy, M.D., David Axelson, B.A., K. Ranga Rama Krishnan, M.D. NR43 Noradrenergic System Changes Induced by Electroconvulsive Shock Stephen K. Brannan, M.D., David J. Jones, Ph.D., Alexander Miller, M.D. NR44 The Hawaii Experience with Water Intoxication Linda S. Godleski, M.D., Kenneth Luke, M.D., Barry Carlton, M.D. NR45 Differential Induction of Early Genes by Neuroleptics Patrick Rogue, M.D., Anant N. Malviya, Ph.D., Guy Vincendon, M.D. NR46 Transcription Block and Reduced Nuclear Protein Kinase C Activation During Aging Patrick Rogue, M.D., Guy Vincendon, M.D., Anant N.