The Pharmaceutical Industry in Germany
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INDUSTRY OVERVIEW The Pharmaceutical Industry in Germany ISSUE 2017/2018 THE PHARMACEUTICAL INDUSTRY IN GERMANY An Ideal Location for Research, Production and Sales Germany offers the perfect location for the de- global growth markets, with the pharmaceutical velopment, production and sale of world-class industry in Germany already a significant global pharmaceuticals. The country benefits from industry player. Germany is home to Europe’s larg- cutting-edge research, a long production tradition est – and the world’s fourth largest – pharma- and immediate market access to pharmaceuticals. ceuticals market. A highly attractive R&D location, Global demand for pharmaceuticals is growing the country ranks first and second in clinical trial continuously as the result of a growing world terms in Europe and the world respectively. Hav- population and demographic change. Together ing established itself as the “world’s pharmacy” as with significant research advances, especially in part of a tradition of medical innovation, Germany the field of medical biotechnology, these develop- is also the world’s leading medical biopharmaceu- ments are providing a spur to the pharmaceutical ticals producer – second only to the USA. industry worldwide. The healthcare industry has evolved to become one of the most important Sweden Finland Russia Germany’s pharma- h by plane ceutical industry – Norway 3 at the market Estonia crossroads of Europe Latvia 1.5 h Lithuania Denmark RU Belarus Ireland UK Netherlands Poland 15 h 30 h by train Belgium GERMANY Ukraine Luxembourg Czechia Slovak Moldova Republic France Austria Hungary Romania Switzerland 12 h Slovenia Croatia Serbia Bosnia- Herzegovina Bulgaria Kosovo Montenegro h by truck Italy 24 Macedonia Portugal Albania Turkey Greece Spain Malta 2 Industry Overview 2017/18 | gtai.com The Industry in Numbers In 2014, healthcare spending in Germany totaled In Germany the generic volume share is much EUR 328 billion (more than four percent increase higher, having reached 77 percent in 2015 with a compared to 2013). This equates to 11.2 percent value of more than EUR 2 billion. Beyond conven- of German GDP (EUR 4,050 per capita). Of this tional medicines, natural medicines have gained a sum, 14 percent is spent on pharmaceutical significant share of the German pharmaceuticals products. Increased demand for medicines and market. Herbals and homeopathic medicines play the introduction of new drugs onto the market an increasingly significant role, particularly in the are the main drivers of spending growth accor- self-medication market. ding to the OECD. With its domestic pharmaceutical industry consisting of companies such as Bayer, BASF and Revenue and Growth in Germany’s Hoechst, Germany has a historical reputation as Pharmaceutical Industry the world’s pharmacy. The sector enjoys market stability. In 2014, the pharmaceutical industry Revenue in EUR billion consisted of more than 640 companies, employing Growth in percent 5.7 5.6 a workforce of 112,500. Pharmaceutical companies 5.4 can be found in all parts of Germany, with higher concentrations around the cities of Hamburg, Berlin, Cologne, Frankfurt, and Munich. With rev- enue of EUR 38 billion in 2015, Germany is the 2.0 1.6 world’s fourth-largest pharmaceuticals market. 380 Germany’s share of the global pharmaceutical 362 342 market remained at around 13.5 percent. The 326 319 pharmaceutical industry in Germany imported pharmaceuticals to the value of almost EUR 41 2011 2012 2013 2014 2015 billion in 2015 and recorded an export rate of nearly 66 percent in 2014. Source: Federal Statistical Office 2015 Pharmaceutical spending in the statutory health insurance sector reached a new high of EUR 37 billion in 2015, recording an annual spending increase of 4.3 percent or more than EUR 1.5 Employment in the Pharmaceutical Industry by billion. The number of packages sold in the Ger- Country 2015 man pharmacy market increased three percent from 1.43 billion in 2014 to 1.47 billion in 2015. Germn 112,475 The annual increase in the German pharmacy market – both in euro and unit transaction vol- umes – was largely achieved through prescription Frnce 92,650 drugs and pharmacy medicine. Generic medicines considerably contribute to European drug supply. Germany aims to balance between rewarding U 64,000 innovations through attractive pricing while, at the same time, fostering generics. In most European countries, the market share of generic Itl 63,000 medicines in volume terms exceeds 40 percent of generics-eligible segments. Source: EFPIA 2016 3 MARKET OPPORTUNITIES Largest Health Economy Growing Market Healthcare Expenditure in Germany Catering to the largest population in Europe (81 in EUR billion million), Germany’s healthcare sector is a highly attractive market with significant growth oppor- tunities. A steady increase in life expectancy levels has led to a rise of chronic and age-related illnesses. Improved health awareness has further increased consumer demand for medicinal prod- ucts and therapies. In 2014, healthcare spending 328 315 in Germany exceeded EUR 328 billion, not in- 303 296 cluding out-of-pocket expenditure for health- care (equivalent to 11.2 percent of GDP). Health Insurance Opportunities Germany provides ready access to a stable mar- 2011 2012 2013 2014 ket of healthcare consumers with a clear and Source: Federal Statistical Office 2015 adequately distributed expenditure system. The German healthcare system is funded by govern- ment and private contributions. The public system is largely financed by members’ contributions total healthcare expenses in 2015. Private health as payroll taxes by the employer and employed, insurance companies reimbursed an additional with the rest coming from government subsidies. EUR 23.2 billion of medical expenses. The remain- With around 88 percent of the German popula- ing amount is covered by government budgets, tion enrolled in a public health insurance plan, the state-mandated long-term care insurers, the social public health insurance system plays the major role pension fund, state-mandated accident insurance in the allocation of healthcare funds. An additional providers, employers, and private households. eleven percent of the population opts for private More than 20 percent of the publicly insured pop- health insurance. Germany’s 123 public health ulation has an additional private health insurance insurance providers covered EUR 213.7 billion of policy to complement their basic healthcare provi- sion. A recent development has been the trend amongst private individuals to spend more money on out-of-pocket medicine and therapy purchases. Pharmaceutical Market Share Differentiation Most out-of-pocket payments are made to pur- share of revenue chase over-the-counter (OTC) drugs and in the form of co-payments for prescribed drugs. Hospital Demographic Change market (13%) Longer life expectancy levels and declining fertil- Pharmacy Over-the-counter 12% Homeopathics 1% ity rates mean that older people account for a market (87%) Herbal medicines 2% larger proportion of the population in Germany. At least one quarter of the population will be over 65 Prescription only 75% Biotech 19% years of age in 2050. The proportion of the popu- lation aged over 80 is expected to almost triple between 2010 and 2050 (rising from 5 percent to Chemical products 65% 15 percent). Accelerating urbanization and more sedentary lifestyles lead to higher obesity rates and chronic diseases such as diabetes. According to the World Health Organization, worldwide chronic disease prevalence is expected to rise by 57 percent by the year 2020. Increased demand Prescription Product made on healthcare systems due to noncommuni- status type cable disease has become a major concern. Source: IMS Health Report 2016 4 Industry Overview 2017/18 | gtai.com Production Location High Production Standards Chemical Industry Strength Germany is an ideal production location for Pharmaceutical companies also benefit from research-intensive, high-grade products. It places the strong international position of the German a high value on technology; this stemming from chemical industry. As a location for the production the country’s long history of developing and man- of chemicals, Germany places first in Europe and ufacturing high-quality pharmaceutical products. third globally – accounting for a quarter of Euro- The country’s particular strength lies in producing pean chemical production in 2015. A number of complex products where containment and sterile outstanding chemical parks in Germany offer environments are critical. Hundreds of thousands specific infrastructural benefits to potential of highly skilled employees in medical-technical, pharmaceutical industry investors. pharmaceutical-technical and engineering back- grounds enable companies to utilize efficient and complex production processes. EU Pharmaceutical Industry Production 2014 Major Production Location in EUR billion Germany counts among the world’s top five phar- maceutical production locations, with a production volume of EUR 30.4 billion in 2014 (equivalent to an almost five percent increase over 2013). Within 304 290 the European Union, no other country produces more drugs than Germany. Internationally, Ger- many also has the largest fermentation capaci- 210 193193 ties – second only to the USA – and is home to 175 the very latest facilities for biomanufacturing. 175 139 Pharmaceutical companies in Germany also ben- efit from close proximity to leading machinery 139 and equipment manufacturers,