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Genotype - Reflex Phenotype Test Number: 3811200 Revision Date: 08/30/2015 LOINC Code: Not Specified

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Genotype - Reflex Phenotype Test Number: 3811200 Revision Date: 08/30/2015 LOINC Code: Not Specified Regional Medical Laboratory 4142 South Mingo Road Tulsa, OK. 74146-3632 Order Name: ALPH 1 GEN Alpha-1 Antitrypsin, Genotype - Reflex Phenotype Test Number: 3811200 Revision Date: 08/30/2015 LOINC Code: Not Specified TEST NAME METHODOLOGY LOINC CODE Alpha-1-Antitrypsin Immunoturbidimetry 1825-9 Alpha-1-Antitrypsin S Allele PCR/Fluorescence Monitoring 1829-1 Alpha-1-Antitrypsin Z Allele PCR/Fluorescence Monitoring 1831-7 Alpha-1-Antitrypsin Interpretation 1830-9 Alpha-1-Antitrypsin Phenotype Isolectric Focusing 49244-7 SPECIMEN REQUIREMENTS Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment Preferred See Instructions EDTA Whole Blood & EDTA (lavender top) and Clot Refrigerated Serum Activator SST (Red/Gray or Tiger Top) Instructions Collect BOTH Serum separator tube AND lavender (EDTA) Allow serum to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transport: 1.0 mL (0.5mL) Serum AND 3 mL(0.5mL) Whole blood Refrigerated. GENERAL INFORMATION Testing Schedule Varies Expected TAT 2-10 Days Notes Alpha-1-antitrypsin serum protein concentration determination and A1A genotyping are performed on all specimens. If two deficiency alleles (ZZ, SZ, or SS) are detected, then no further testing will be added. If the protein concentration is less than 90 mg/dL and only one or no deficiency allele is detected by A1A genotyping, then phenotyping will be added. Additional charges apply. CPT Code(s) 82103, 81332; If reflexed, add 82104 Lab Section Reference Lab Service provided by Regional Medical Laboratory - Visit us Online at: www.rmlonline.com All Rights Reserved. © 2013 - 2015 Regional Medical Laboratory 4142 South Mingo Road Tulsa, OK. 74146-3632 Order Name: AMIODARON Amiodarone Test Number: 3653300 Revision Date: 08/17/2015 LOINC Code: Not Specified LOINC TEST NAME METHODOLOGY CODE Amiodarone Quantitative Liquid 3330-8 Chromatography-Tandem Mass Spectrometry N-Desethyl-Amiodarone Quantitative Liquid 6774-4 Chromatography-Tandem Mass Spectrometry SPECIMEN REQUIREMENTS Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment Preferred 1mL (0.5mL) Serum Clot Activator (Red Top, No-Gel) Refrigerated Instructions Timing of specimen collection: Pre-dose (trough) draw - at steady state concentration. Separate serum or plasma from cells within 2 hours of collection. Unacceptable Conditions: Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution). Stability: After separation from cells: Ambient: 1 month; Refrigerated: 6 weeks; Frozen: 6 weeks. GENERAL INFORMATION Testing Schedule Mon-Fri Expected TAT 2-5 Days Clinical Use Amiodarone is an antiarrythmic drug. Therapeutic drug monitoring is useful to monitor compliance and avoid toxicity. Methodology: High Performance Liquid Chromatography (HPLC) or Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS). CPT Code(s) 80299 Lab Section Reference Lab Service provided by Regional Medical Laboratory - Visit us Online at: www.rmlonline.com All Rights Reserved. © 2013 - 2015 Regional Medical Laboratory 4142 South Mingo Road Tulsa, OK. 74146-3632 Order Name: BOR PR AB Bordetella pertussis Antibodies, IgA and IgG by Test Number: 5521005 ELISA with Reflex to Immunoblot Revision Date: 08/30/2015 LOINC Code: Not Specified LOINC TEST NAME METHODOLOGY CODE Bordetella pertussis Antibody IgA Enzyme-Linked Immunosorbent 42328-5 Assay Bordetella pertussis Antibody IgG Enzyme-Linked Immunosorbent 42330-1 Assay SPECIMEN REQUIREMENTS Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment Preferred 1 mL (0.3 mL) Serum Clot Activator SST (Red/Gray or Refrigerated Tiger Top) Instructions Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent." Separate serum from cells ASAP or within 2 hours of collection. Unacceptable Conditions: Contaminated, heat-inactivated, or severely lipemic specimens. Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) GENERAL INFORMATION Testing Schedule 2-6 Days Expected TAT Tue, Fri Notes If Bordetella pertussis Antibody, IgA by ELISA is 1.2 U/mL or greater, then Bordetella pertussis IgA Immunoblot testing will be added; if Bordetella pertussis Antibody, IgG by ELISA is 1.0 U/mL or greater, then Bordetella pertussis IgG Immunoblot testing will be added. Additional charges apply. CPT Code(s) 86615x2; if reflexed, add 86615 for each Immunoblot Lab Section Reference Lab Service provided by Regional Medical Laboratory - Visit us Online at: www.rmlonline.com All Rights Reserved. © 2013 - 2015 Regional Medical Laboratory 4142 South Mingo Road Tulsa, OK. 74146-3632 Order Name: BOR P IGA Bordetella pertussis Antibody, IgA by Immunoblot Test Number: 5521045 Revision Date: 08/30/2015 LOINC Code: Not Specified TEST NAME METHODOLOGY LOINC CODE B. pertussis, IgA Immunoblot FHA Qualitative Immunoblot 43880-4 B. pertussis, IgA Immunoblot PT Qualitative Immunoblot 23830-3 B. pertussis Ab, IgA Immunoblot Interpretation 29672-3 SPECIMEN REQUIREMENTS Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment Preferred 1 mL (0.15 mL) Serum Clot Activator SST (Red/Gray or Refrigerated Tiger Top) Instructions Separate serum from cells ASAP or within 2 hours of collection. Unacceptable Conditions: Contaminated or heat-inactivated specimens. Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year GENERAL INFORMATION Testing Schedule 2-6 Days Expected TAT Tue, Fri Clinical Use This assay tests for the presence of pertussis toxin (PT) and filamentous hemagglutinin antibody (FHA). CPT Code(s) 86615 Lab Section Reference Lab Service provided by Regional Medical Laboratory - Visit us Online at: www.rmlonline.com All Rights Reserved. © 2013 - 2015 Regional Medical Laboratory 4142 South Mingo Road Tulsa, OK. 74146-3632 Order Name: BOR P IGG Bordetella pertussis Antibody, IgG by Immunoblot Test Number: 5521020 Revision Date: 08/30/2015 LOINC Code: Not Specified TEST NAME METHODOLOGY LOINC CODE B. pertussis, IgG Immunoblot FHA Qualitative Immunoblot 29674-9 B. pertussis, IgG Immunoblot PT Qualitative Immunoblot 69367-1 B. pertussis, IgG Immunoblot PT100 Qualitative Immunoblot 20992-4 B. pertussis Ab, IgG Immunoblot Interpretation 29674-9 SPECIMEN REQUIREMENTS Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment Preferred 1 mL (0.15 mL) Serum EDTA (lavender top) and Clot Refrigerated Activator SST (Red/Gray or Tiger Top) Instructions Separate serum from cells ASAP or within 2 hours of collection. Unacceptable Conditions: Heat-inactivated specimens. Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year GENERAL INFORMATION Testing Schedule Tue, Fri, Sun Expected TAT 2-5 Days Clinical Use This assay tests for the presence of pertussis toxin (PT), pertussis toxin PT 100 (PT-100), and filamentous hemagglutinin antibody (FHA). CPT Code(s) 86615 Lab Section Reference Lab Service provided by Regional Medical Laboratory - Visit us Online at: www.rmlonline.com All Rights Reserved. © 2013 - 2015 Regional Medical Laboratory 4142 South Mingo Road Tulsa, OK. 74146-3632 Order Name: CAT FRAC U Catecholamines, Fractionated, 24-Hour or Random Test Number: 3808550 Urine Revision Date: 08/17/2015 LOINC Code: Not Specified LOINC TEST NAME METHODOLOGY CODE Epinephrine, Urine - per 24h Quantitative HPLC/Tandem Mass 2232-7 Spectrometry Epinephrine, Urine - ratio to Creatinine Quantitative HPLC/Tandem Mass 13734-9 Spectrometry Norepinephrine, Urine - per 24h Quantitative HPLC/Tandem Mass 2668-2 Spectrometry Norepinephrine, Urine - ratio to Creatinine Quantitative HPLC/Tandem Mass 13782-8 Spectrometry Dopamine, Urine - per 24h Quantitative HPLC/Tandem Mass 2218-6 Spectrometry Dopamine, Urine - ratio to Creatinine Quantitative HPLC/Tandem Mass 13733-1 Spectrometry Creatinine, Urine - per 24h Spectrophotometry 2162-6 Creatinine, Urine Spectrophotometry 20624-3 Catecholamines, Urine Interpretation 49256-1 SPECIMEN REQUIREMENTS Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment Preferred 4 mL (2.5) Urine, 24-hour 24 hour Urine Container Refrigerated Alternate 1 4 mL (2.5) Urine, Random Sterile Urine container Refrigerated Instructions Transfer a 4 mL aliquot from a well-mixed 24-hour or random collection to a standard transport tube. Mark collection duration and total volume on transport tube and test request form. Adequate refrigeration is the most important aspect of specimen preservation. Preservation can be enhanced by adjusting the pH to 2-4 by adding an acid such as 6 mol/L HCl. Catecholamines are not stable above pH 7. The pH of such specimens must be adjusted by the addition of acid prior to transport. A pH less than 2 can cause assay interference. Stability: Ambient= N/A; Refrigerated= 1 month; Frozen= 6 months. Dietary Instructions: Drugs and medications may affect results and should be discontinued for at least 72 hours prior to specimen collection, if possible. GENERAL INFORMATION Testing Schedule Sun-Sat Expected TAT 2-3 Days Clinical Use This test includes: Dopamine, Epinephrine and Norepinephrine. Notes It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers,
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