1 Reconstructing the Population History of Puerto Rico by means of mtDNA Phylogeographic Analysis Juan C. Martínez-Cruzado1, Gladys Toro-Labrador1, Jorge Viera-Vera1, Michelle Y. Rivera- Vega1,2, Jennifer Startek1, Magda Latorre-Esteves1,3, Alicia Román-Colón1,4, Rebecca Rivera- Torres1,5, Iris Y. Navarro-Millán1,2, Enid Gómez-Sánchez1, Héctor Y. Caro-González1,6, and Patricia Valencia-Rivera1,7 1Department of Biology, University of Puerto Rico at Mayagüez, Mayagüez, PR 00680; 2Escuela de Medicina, Universidad Autónoma de Guadalajara, Guadalajara, Jalisco, CP45110, MÉXICO; 3Department of Pathology, Harvard Medical School, Harvard University, Boston, MA 02115; 4Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936; 5Department of Comparative Pathology, University of California at Davis, Davis, CA 95616; 6Department of Biological Sciences, Stanford University, Stanford, CA 94305; 7Department of Cell Biology, Harvard Medical School, Harvard University, Boston, MA 02115 Total number of pages: 82 Abbreviated title: Puerto Rico mtDNA phylogeography Key words: mtDNA haplogroups; Taínos; principal component analysis 2 Address for correspondence: Dr. Juan C. Martínez-Cruzado, Department of Biology, University of Puerto Rico at Mayagüez, PO Box 9012, Mayagüez, Puerto Rico 00681-9012, USA. Tel: (787) 832-4040 X-3357, 3751, 2405. Fax: (787) 265-3837. E-mail:
[email protected] Grant sponsorship: NSF Physical Anthropology Program grant SBR-9904252 to JCMC. 3 ABSTRACT The haplogroup identities of 800 mtDNAs randomly and systematically selected to be representative of the population of Puerto Rico were determined by AFLP, revealing maternal ancestries in this highly mixed population of 61.3% Amerindian, 27.2% Sub-Saharan African, and 11.5% West Eurasian.