Curriculum Vitae Dr Matthew Hartfield
Institute of Evolutionary Biology University of Edinburgh, Charlotte Auerbach Road Edinburgh EH9 3FL, UK [email protected] British Citizen
EMPLOYMENT
2018 – Present: NERC Independent Research Fellow Institute of Evolutionary Biology, University of Edinburgh, UK
2017 – 2018: Postdoctoral Researcher Bioinformatics Research Centre, Aarhus University, Denmark Supervisor: Dr Thomas Bataillon
2014 – 2017: Marie Curie International Outgoing Fellow Department of Ecology and Evolutionary Biology, University of Toronto, Canada (2014 – 2016): Bioinformatics Research Centre, Aarhus University, Denmark (2016– 2017) Outgoing Hosts: Profs Aneil Agrawal and Stephen Wright Return Host: Dr Thomas Bataillon
2012 – 2014: CNRS Research Fellow ('CDD Chercher') Team MIVEGEC, IRD Montpellier, France Supervisor: Dr Samuel Alizon
EDUCATION
2008 – 2012: PhD Evolutionary Biology Institute of Evolutionary Biology, University of Edinburgh, UK Supervisor: Prof. Peter D. Keightley
2007 – 2008: MSc Mathematical Biology University of Bath, UK Degree Class: Pass with Distinction Thesis supervisors: Dr Jane White and Dr Klaus Kurtenbach
2003 – 2007: MSci Mathematics Imperial College of Science, Technology and Medicine, London, UK. Degree Class: First Class (Honours)
Page 1 of 5 FUNDING AND SOCIETAL AWARDS
Major Awards:
1) NERC Independent Research Fellowship. 5 years (2018 – 2023); £518,440. 2) John Maynard Smith Prize, European Society for Evolutionary Biology. 3) Marie Curie International Outgoing Fellowship. 3 years (2014 – 2017); 271,642.50€.
Other Awards:
4) 2018: American Society of Naturalists, towards a visit to the II Joint Congress on Evolutionary Biology (Montpellier, France). $500. 5) 2011: University of Edinburgh’s James Rennie Bequest, towards a visit to ESEB in Tübingen, Germany. £200. 6) 2010: Genetics Society UK, towards a visit to Evolution in Portland OR, USA. £500. 7) 2009: University of British Columbia Graduate Student International Research Mobility Award, to visit Sally Otto. CAD $1,500.
PUBLICATIONS IN PEER-REVIEWED INTERNATIONAL JOURNALS
Preprints:
1) Hartfield M., Bataillon T. Selective sweeps under dominance and self-fertilisation. Preprint available on bioRxiv, doi: http://doi.org/10.1101/318410.
Accepted articles:
2) Hartfield M., Wright S. I. and Agrawal A. F. Coalescence and linkage disequilibrium in facultatively sexual diploids. Accepted for publication in Genetics.
3) Hartfield M. (2018) Digest: Effects of spatially–spreading adaptive mutations on genome–wide diversity. Evolution, 72(4); 1015–1016.
4) Hartfield M., Bataillon T. and Glémin S. (2017) The evolutionary interplay between adaptation and self-fertilization. Trends in Genetics, 33(6); 420—431.
5) Hartfield M. (2016) On the origin of asexual species by means of hybridisation and drift. Molecular Ecology, 25(14); 3264—3265. Invited commentary.
6) Hartfield M., Glémin S. (2016) Limits to adaptation in partially selfing species. Genetics, 203(2); 959–974.
7) Betancourt A.J., Hartfield M. (2016) Recombination and Molecular Evolution. Book chapter in Encyclopedia of Evolutionary Biology, 411–416.
8) Hartfield M. (2016) Evolutionary genetic consequences of low outcrossing rates. Journal of Evolutionary Biology, 29(1); 5–22. Invited review.
9) Hartfield M., Wright S. I. and Agrawal A. F. (2016) Coalescent times and patterns of genetic diversity in species with facultative sex: effects of gene conversion, population structure and heterogeneity. Genetics, 202(1); 297–312.
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10) Agrawal A. F., Hartfield M. (2016) Coalescence with background and balancing selection in systems with bi- and uniparental reproduction: contrasting partial asexuality and selfing. Genetics, 202(1); 313–326.
11) Hartfield M., Alizon S. (2015) Within-host stochastic emergence dynamics of immune escape mutants. PLoS Computational Biology, 11(3); e1004149.
12) Hartfield M., Murall C.L., Alizon S. (2014) Clinical Applications of Pathogen Phylogenies. Trends in Molecular Medicine, 20(7): 394–404.
13) Hartfield M., Bull R., White P.A., Lloyd A.R., Luciani F. and Alizon S. (2014) Evidence that HCV genome partly controls infection outcome. Evolutionary Applications, 7(5): 533–547.
14) Hartfield M., Alizon S. (2014) Epidemiological feedbacks affect evolutionary emergence of pathogens. The American Naturalist, 183(4): E105–E117.
15) Hartfield M., Glémin S. (2014) Hitchhiking of deleterious alleles and the cost of adaptation in partially selfing species. Genetics, 196(1): 281–293. Selected by Faculty of 1000. Cover Story for Issue.
16) Hartfield M., Alizon S. (2013) Introducing the Outbreak Threshold. PLoS Pathogens, 9(6); e1003277.
17) Hartfield M., Otto S.P. and Keightley P.D. (2012) The maintenance of obligate sex in finite, structured populations subject to recurrent beneficial and deleterious mutation. Evolution, 66(12): 3658—3669.
18) Hartfield M. (2012) A framework for estimating the fixation time of an advantageous allele in stepping-stone models. Journal of Evolutionary Biology, 25(9): 1751—1764.
19) Hartfield M., Keightley P.D. (2012) Current hypotheses regarding the evolution of sex and recombination. Integrative Zoology, 7(2): 192—209.
20) Hartfield M., Otto S.P. (2011) Recombination and Hitchhiking of Deleterious Alleles. Evolution, 65(9): 2421—2434. Selected by Faculty of 1000.
21) Hartfield M., White K.A.J. and Kurtenbach K. (2011) The role of deer in facilitating the spatial spread of the pathogen Borrelia burgdorferi. Theoretical Ecology, 4(1), 27—36.
22) Hartfield M., Otto S.P. and Keightley P.D. (2010) The Role of Advantageous Mutations in Enhancing the Evolution of a Recombination Modifier. Genetics, 184(4): 1153—1164.
REVIEWING EXPERIENCE
Reviewing undertaken for peer-reviewed journals: BMC Genetics; Ecology and Evolution; Evolution; Genetics; Heredity; Journal of Evolutionary Biology; Journal of the Royal Society, Interface; Journal of Theoretical Biology; Molecular Ecology; Nature Communications; New Phytologist; PLoS Genetics; PLoS ONE;
Page 3 of 5 Proceedings of the Royal Society B; Philosophical Transactions of the Royal Society B (both papers and themed issue proposals); Royal Society Open Science; Theoretical Population Biology; Trends in Ecology and Evolution.
Guest Editor: PLoS Computational Biology.
Grant proposals: Israel Science Foundation; National Science Foundation (USA).
Other: “Recommender” for Peer Community in Evolutionary Biology (seeks out reviewers to assess and recommend preprint articles).
SELECTED SEMINARS, CONFERENCE AND INVITED TALKS
Invited talks:
1) Jul 2018: Max Planck Institute for Plant Breeding Research, Cologne, Germany.
2) Apr 2018: Jacques Monod Conference (“Sex uncovered: the evolutionary biology of reproductive systems”), Roscoff, France.
3) Apr 2017: French National Institute for Agricultural Research (INRA), Montpellier, France.
4) Mar 2016: Department of Maths and Stats, Queen’s University, Kingston ON, Canada.
5) Dec 2015: Department of Ecology and Genetics, Uppsala University, Sweden.
6) Aug 2015: John Maynard Smith Prize talk, ESEB 15, Lausanne, Switzerland.
7) Oct 2014: Ecology and Evolution Seminar, Department of Biology, McMaster University, Hamilton ON, Canada.
8) Jun 2014: 9th European Conference on Mathematical and Theoretical Biology (ECMTB), Gothenburg, Sweden. Speaker for mini–symposium “Rapid adaptation to novel environments”.
9) Nov 2013: BiRC (Bioinformatics Research Centre) Seminar, Aarhus, Denmark.
10) Oct 2013: Ecology & Evolution Seminar, Université Pierre et Marie Curie/Ecole Normale Supérieure, Paris, France.
11) Nov 2011: Biomathematics Seminar, University of Vienna.
Contributed talks:
12) Aug 2018 (to be given): Joint ESEB/SSE Evolution Congress, Montpellier, France.
13) Jan 2018: Popgroup 51 Meeting, University of Bristol, UK. I have been a regular attendee at these meetings since 2010.
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14) Sept 2017: Probabilistic Modeling in Genomics, Aarhus, Denmark.
15) Jun 2016, 2010: Evolution Meetings in Austin TX, USA; Portland OR, USA.
16) Apr 2014: British Society for Parasitology (BSP) Spring Meeting, Cambridge, UK.
17) Aug 2013; 2011: ESEB Meetings in Lisbon, Portugal; Tübingen, Germany.
18) May 2013: Jacques Monod Conference: Recent advances on the evolution of sex and genetic systems, Roscoff, France (Poster).
19) Aug 2009: EMPSEB 15, Schoorl, Netherlands. Awarded conference prize.
TEACHING EXPERIENCE
1) 2017: Presented guest lecture on the structured coalescent at BIRC, Aarhus University. 2) 2012: Demonstrated on MSc Bioinformatics course; 1st year Biology, Ecology and the Environment course at University of Edinburgh. 3) 2009–2011: Tutored MSc course on Population and Quantitative Genetics, and 3rd year course on Evolutionary and Ecological Genetics at University of Edinburgh.
MENTORING EXPERIENCE
1) 2013: Co-Supervised master's project of Adelaïde Dubois, ISEM, University of Montpellier 2. 2) 2011: Co-Supervised fourth-year honours project, Leo Dunstan, undergraduate in Biology at University of Edinburgh.
SCIENTIFIC OUTREACH
1) Write and maintain own blog about evolutionary biology (http://matthartfield.wordpress.com/); contributor to online blogs about my research (for example, http://haldanessieve.org/2015/05/21/author-post-coalescent-times-and-patterns- of-genetic-diversity-in-species-with-facultative-sex/). 2) Extensively involved with EUSci magazine (http://www.eusci.org.uk/) during PhD at Edinburgh. Wrote feature articles and contributed to podcast. 3) EUSci society president 2009–10. During this time, I helped obtain funding to set up seminar series, where junior researchers informally discussed their work.
PROFESSIONAL SERVICE
1) 2016–2018: Co–Organiser of Genetics Journal Club, BIRC, Aarhus University. 2) 2015: Organiser of Plant Evolutionary Genetics lab meetings, EEB, University of Toronto. 3) 2015: Organiser of Evolutionary Genetics Journal Club, EEB, University of Toronto. 4) 2012–2014: Organiser of fortnightly journal club, IRD Montpellier.
PROFESSIONAL MEMBERSHIPS
Genetics Society UK; Society for the Study of Evolution (SSE); American Society of Naturalists (ASN); European Society for Evolutionary Biology (ESEB).
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